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Fusion gene ID: 31499 |
FusionGeneSummary for RNF19A_F10 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: RNF19A_F10 | Fusion gene ID: 31499 | Hgene | Tgene | Gene symbol | RNF19A | F10 | Gene ID | 25897 | 83541 |
| Gene name | ring finger protein 19A, RBR E3 ubiquitin protein ligase | family with sequence similarity 110 member A | |
| Synonyms | RNF19 | C20orf55|F10|bA371L19.3 | |
| Cytomap | 8q22.2 | 20p13 | |
| Type of gene | protein-coding | protein-coding | |
| Description | E3 ubiquitin-protein ligase RNF19Adouble ring-finger proteinprotein p38 interacting with transcription factor Sp1ring finger protein 19ring finger protein 19A, E3 ubiquitin protein ligasering-IBR-ring domain containing protein Dorfin | protein FAM110A | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q9NV58 | P00742 | |
| Ensembl transtripts involved in fusion gene | ENST00000341084, ENST00000519449, ENST00000523255, | ENST00000409306, ENST00000375551, ENST00000375559, ENST00000483537, | |
| Fusion gene scores | * DoF score | 15 X 11 X 8=1320 | 5 X 4 X 4=80 |
| # samples | 19 | 4 | |
| ** MAII score | log2(19/1320*10)=-2.79646660591487 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(4/80*10)=-1 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: RNF19A [Title/Abstract] AND F10 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | ESCA | TCGA-VR-A8EX-01A | RNF19A | chr8 | 101299729 | - | F10 | chr13 | 113792771 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000341084 | ENST00000409306 | RNF19A | chr8 | 101299729 | - | F10 | chr13 | 113792771 | + |
| In-frame | ENST00000341084 | ENST00000375551 | RNF19A | chr8 | 101299729 | - | F10 | chr13 | 113792771 | + |
| In-frame | ENST00000341084 | ENST00000375559 | RNF19A | chr8 | 101299729 | - | F10 | chr13 | 113792771 | + |
| 5CDS-intron | ENST00000341084 | ENST00000483537 | RNF19A | chr8 | 101299729 | - | F10 | chr13 | 113792771 | + |
| In-frame | ENST00000519449 | ENST00000409306 | RNF19A | chr8 | 101299729 | - | F10 | chr13 | 113792771 | + |
| In-frame | ENST00000519449 | ENST00000375551 | RNF19A | chr8 | 101299729 | - | F10 | chr13 | 113792771 | + |
| In-frame | ENST00000519449 | ENST00000375559 | RNF19A | chr8 | 101299729 | - | F10 | chr13 | 113792771 | + |
| 5CDS-intron | ENST00000519449 | ENST00000483537 | RNF19A | chr8 | 101299729 | - | F10 | chr13 | 113792771 | + |
| intron-3CDS | ENST00000523255 | ENST00000409306 | RNF19A | chr8 | 101299729 | - | F10 | chr13 | 113792771 | + |
| intron-3CDS | ENST00000523255 | ENST00000375551 | RNF19A | chr8 | 101299729 | - | F10 | chr13 | 113792771 | + |
| intron-3CDS | ENST00000523255 | ENST00000375559 | RNF19A | chr8 | 101299729 | - | F10 | chr13 | 113792771 | + |
| intron-intron | ENST00000523255 | ENST00000483537 | RNF19A | chr8 | 101299729 | - | F10 | chr13 | 113792771 | + |
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FusionProtFeatures for RNF19A_F10 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| RNF19A | F10 |
| E3 ubiquitin-protein ligase which accepts ubiquitin fromE2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form ofa thioester and then directly transfers the ubiquitin to targetedsubstrates, such as SNCAIP or CASR. Specifically ubiquitinatespathogenic SOD1 variants, which leads to their proteasomaldegradation and to neuronal protection.{ECO:0000269|PubMed:11237715, ECO:0000269|PubMed:12145308,ECO:0000269|PubMed:12750386, ECO:0000269|PubMed:15456787,ECO:0000269|PubMed:16513638}. | Factor Xa is a vitamin K-dependent glycoprotein thatconverts prothrombin to thrombin in the presence of factor Va,calcium and phospholipid during blood clotting. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | RNF19A | chr8:101299729 | chr13:113792771 | ENST00000341084 | - | 2 | 10 | 132_179 | 224 | 839 | Zinc finger | RING-type 1 |
| Hgene | RNF19A | chr8:101299729 | chr13:113792771 | ENST00000519449 | - | 3 | 11 | 132_179 | 224 | 839 | Zinc finger | RING-type 1 |
| Tgene | >F10 | chr8:101299729 | chr13:113792771 | ENST00000375559 | + | 1 | 8 | 125_165 | 77 | 489 | Domain | EGF-like 2 |
| Tgene | >F10 | chr8:101299729 | chr13:113792771 | ENST00000375559 | + | 1 | 8 | 235_467 | 77 | 489 | Domain | Peptidase S1 |
| Tgene | >F10 | chr8:101299729 | chr13:113792771 | ENST00000375559 | + | 1 | 8 | 86_122 | 77 | 489 | Domain | EGF-like 1%3B calcium-binding |
| Tgene | >F10 | chr8:101299729 | chr13:113792771 | ENST00000375559 | + | 1 | 8 | 183_203 | 77 | 489 | Region | Note=O-glycosylated at one site |
| Tgene | >F10 | chr8:101299729 | chr13:113792771 | ENST00000375559 | + | 1 | 8 | 476_485 | 77 | 489 | Region | Note=O-glycosylated at one site |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >RNF19A | chr8:101299729 | chr13:113792771 | ENST00000341084 | - | 2 | 10 | 368_388 | 224 | 839 | Transmembrane | Helical |
| Hgene | >RNF19A | chr8:101299729 | chr13:113792771 | ENST00000341084 | - | 2 | 10 | 424_444 | 224 | 839 | Transmembrane | Helical |
| Hgene | >RNF19A | chr8:101299729 | chr13:113792771 | ENST00000519449 | - | 3 | 11 | 368_388 | 224 | 839 | Transmembrane | Helical |
| Hgene | >RNF19A | chr8:101299729 | chr13:113792771 | ENST00000519449 | - | 3 | 11 | 424_444 | 224 | 839 | Transmembrane | Helical |
| Hgene | >RNF19A | chr8:101299729 | chr13:113792771 | ENST00000341084 | - | 2 | 10 | 199_264 | 224 | 839 | Zinc finger | Note=IBR-type |
| Hgene | >RNF19A | chr8:101299729 | chr13:113792771 | ENST00000341084 | - | 2 | 10 | 301_332 | 224 | 839 | Zinc finger | RING-type 2 |
| Hgene | >RNF19A | chr8:101299729 | chr13:113792771 | ENST00000519449 | - | 3 | 11 | 199_264 | 224 | 839 | Zinc finger | Note=IBR-type |
| Hgene | >RNF19A | chr8:101299729 | chr13:113792771 | ENST00000519449 | - | 3 | 11 | 301_332 | 224 | 839 | Zinc finger | RING-type 2 |
| Tgene | F10 | chr8:101299729 | chr13:113792771 | ENST00000375559 | + | 1 | 8 | 41_85 | 77 | 489 | Domain | Gla |
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FusionGeneSequence for RNF19A_F10 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_RNF19A_ENST00000341084_chr8_101299729_-_F10_ENST00000409306_chr13_113792771_+_482aa MQEQEIGFISKYNEGLCVNTDPVSILTSILDMSLHRQMGSDRDLQSSASSVSLPSVKKAPKKRRISIGSLFRRKKDNKRKSRELNGGVDG IASIESIHSEMCTDKNSIFSTNTSSDNGLTSISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECT ERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGMNSGINTKMATSVRPVLARTRANVKTASGNTPAPVXKDSKAKTVN YSHGSSAAWTTGTVTSSATRNRTLWCAPAPAGTPWLTTARPAFPQGPTPVGNRPWNAGRGQWPRPPAAAGRPLTASHGSHMMQPTWTPPR TPSTCLTSTRRSLRGATTTSPGSWEARNARTGSVPGRPCSSMRKTRVSVVEPFXASSTSXRQPTVSTKPRDSRXGGPEHGAGGGRXGGAR >In-frame_RNF19A_ENST00000341084_chr8_101299729_-_F10_ENST00000375551_chr13_113792771_+_480aa MQEQEIGFISKYNEGLCVNTDPVSILTSILDMSLHRQMGSDRDLQSSASSVSLPSVKKAPKKRRISIGSLFRRKKDNKRKSRELNGGVDG IASIESIHSEMCTDKNSIFSTNTSSDNGLTSISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECT ERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGMNSGINTKMATSVRPVLARTRANVKTASGNTPAPVXKDSKAKTVN YSHGSSAAWTTGTVTSSATRNRTLWCAPAPAGTPWLTTARPAFPQGPTPVGNRPWNAGRGQWPRPPAAAGRPLTASHGSHMMQPTWTPPR TPSTCLTSTRRSLRGATTTSPGSWEARNARTGSVPGRPCSSMRKTRVSVVEPFXASSTSXRQPTVSTKPRDSRGPEHGAGGGRXGGARGG >In-frame_RNF19A_ENST00000341084_chr8_101299729_-_F10_ENST00000375559_chr13_113792771_+_636aa MQEQEIGFISKYNEGLCVNTDPVSILTSILDMSLHRQMGSDRDLQSSASSVSLPSVKKAPKKRRISIGSLFRRKKDNKRKSRELNGGVDG IASIESIHSEMCTDKNSIFSTNTSSDNGLTSISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECT ERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGMNSGINTKMATSVRPVLARTRANVKTASGNTPAPVXKDSKAKTVN YSHGSSAAWTTGTVTSSATRNRTLWCAPAPAGTPWLTTARPAFPQGPTPVGNRPWNAGRGQWPRPPAAAGRPLTASHGSHMMQPTWTPPR TPSTCLTSTRRSLRGATTTSPGSWEARNARTGSVPGRPCSSMRKTRVSVVEPFXASSTSXRQPTVSTKPRDSRXGXGTGTRSRRRAVRRC TRWRWSSSTTGSQRRPMTSTSPCSGSRPPSPSAXTWRLPASPSVTGPSPRXXRRRRGLXAASGAPTRRAGSPPGSRCWRCPTWTATAASC PAASSSPRTCSVPATTPSRRMPARGTAGARTSPASRTPTSXQASSAGERAVPVRGSTGSTPRSPPSSSGSTGPXKPGACPRPRAMPRRSX >In-frame_RNF19A_ENST00000519449_chr8_101299729_-_F10_ENST00000409306_chr13_113792771_+_482aa MQEQEIGFISKYNEGLCVNTDPVSILTSILDMSLHRQMGSDRDLQSSASSVSLPSVKKAPKKRRISIGSLFRRKKDNKRKSRELNGGVDG IASIESIHSEMCTDKNSIFSTNTSSDNGLTSISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECT ERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGMNSGINTKMATSVRPVLARTRANVKTASGNTPAPVXKDSKAKTVN YSHGSSAAWTTGTVTSSATRNRTLWCAPAPAGTPWLTTARPAFPQGPTPVGNRPWNAGRGQWPRPPAAAGRPLTASHGSHMMQPTWTPPR TPSTCLTSTRRSLRGATTTSPGSWEARNARTGSVPGRPCSSMRKTRVSVVEPFXASSTSXRQPTVSTKPRDSRXGGPEHGAGGGRXGGAR >In-frame_RNF19A_ENST00000519449_chr8_101299729_-_F10_ENST00000375551_chr13_113792771_+_480aa MQEQEIGFISKYNEGLCVNTDPVSILTSILDMSLHRQMGSDRDLQSSASSVSLPSVKKAPKKRRISIGSLFRRKKDNKRKSRELNGGVDG IASIESIHSEMCTDKNSIFSTNTSSDNGLTSISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECT ERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGMNSGINTKMATSVRPVLARTRANVKTASGNTPAPVXKDSKAKTVN YSHGSSAAWTTGTVTSSATRNRTLWCAPAPAGTPWLTTARPAFPQGPTPVGNRPWNAGRGQWPRPPAAAGRPLTASHGSHMMQPTWTPPR TPSTCLTSTRRSLRGATTTSPGSWEARNARTGSVPGRPCSSMRKTRVSVVEPFXASSTSXRQPTVSTKPRDSRGPEHGAGGGRXGGARGG >In-frame_RNF19A_ENST00000519449_chr8_101299729_-_F10_ENST00000375559_chr13_113792771_+_636aa MQEQEIGFISKYNEGLCVNTDPVSILTSILDMSLHRQMGSDRDLQSSASSVSLPSVKKAPKKRRISIGSLFRRKKDNKRKSRELNGGVDG IASIESIHSEMCTDKNSIFSTNTSSDNGLTSISKQIGDFIECPLCLLRHSKDRFPDIMTCHHRSCVDCLRQYLRIEISESRVNISCPECT ERFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGMNSGINTKMATSVRPVLARTRANVKTASGNTPAPVXKDSKAKTVN YSHGSSAAWTTGTVTSSATRNRTLWCAPAPAGTPWLTTARPAFPQGPTPVGNRPWNAGRGQWPRPPAAAGRPLTASHGSHMMQPTWTPPR TPSTCLTSTRRSLRGATTTSPGSWEARNARTGSVPGRPCSSMRKTRVSVVEPFXASSTSXRQPTVSTKPRDSRXGXGTGTRSRRRAVRRC TRWRWSSSTTGSQRRPMTSTSPCSGSRPPSPSAXTWRLPASPSVTGPSPRXXRRRRGLXAASGAPTRRAGSPPGSRCWRCPTWTATAASC PAASSSPRTCSVPATTPSRRMPARGTAGARTSPASRTPTSXQASSAGERAVPVRGSTGSTPRSPPSSSGSTGPXKPGACPRPRAMPRRSX |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_RNF19A_ENST00000341084_chr8_101299729_-_F10_ENST00000409306_chr13_113792771_+_1448nt ATGCAAGAACAAGAAATAGGTTTTATCTCTAAATATAATGAAGGGCTGTGTGTAAACACTGACCCTGTCTCAATTCTAACAAGCATTTTA GACATGAGTTTACATCGGCAAATGGGTTCAGATCGAGATCTTCAGTCCTCTGCTTCATCTGTGAGCTTGCCTTCAGTCAAAAAGGCACCC AAAAAAAGAAGAATTTCAATAGGCTCCCTGTTTCGGAGGAAAAAAGATAACAAACGTAAATCAAGGGAGCTAAATGGCGGGGTGGATGGA ATTGCAAGTATTGAAAGTATACATTCTGAAATGTGTACTGATAAGAACTCCATTTTCTCTACAAATACCTCTTCTGACAATGGATTAACT TCCATCAGCAAACAAATTGGAGACTTCATAGAGTGCCCTTTGTGCCTTTTGCGGCATTCTAAAGACAGATTTCCTGATATAATGACTTGT CATCACAGATCTTGTGTGGATTGCTTACGACAATATTTAAGGATAGAAATCTCTGAAAGCAGAGTTAATATTAGTTGCCCAGAATGTACT GAACGGTTTAATCCCCATGATATTCGCTTGATATTAAGTGATGATGTCTTGATGGAAAAATACGAAGAATTTATGCTTAGACGGTGGCTT GTTGCAGATCCTGATTGTAGGTGGTGTCCAGCTCCAGACTGTGGAATGAATTCTGGAATAAATACAAAGATGGCGACCAGTGTGAGACCA GTCCTTGCCAGAACCAGGGCAAATGTAAAGACGGCCTCGGGGAATACACCTGCACCTGTTTAGAAGGATTCGAAGGCAAAAACTGTGAAT TATTCACACGGAAGCTCTGCAGCCTGGACAACGGGGACTGTGACCAGTTCTGCCACGAGGAACAGAACTCTGTGGTGTGCTCCTGCGCCC GCGGGTACACCCTGGCTGACAACGGCAAGGCCTGCATTCCCACAGGGCCCTACCCCTGTGGGAAACAGACCCTGGAACGCAGGAAGAGGT CAGTGGCCCAGGCCACCAGCAGCAGCGGGGAGGCCCCTGACAGCATCACATGGAAGCCATATGATGCAGCCGACCTGGACCCCACCGAGA ACCCCTTCGACCTGCTTGACTTCAACCAGACGCAGCCTGAGAGGGGCGACAACAACCTCACCAGGATCGTGGGAGGCCAGGAATGCAAGG ACGGGGAGTGTCCCTGGCAGGCCCTGCTCATCAATGAGGAAAACGAGGGTTTCTGTGGTGGAACCATTCTGAGCGAGTTCTACATCCTAA CGGCAGCCCACTGTCTCTACCAAGCCAAGAGATTCAAGGTGAGGGGGACCGGAACACGGAGCAGGAGGAGGGCGGTGAGGCGGTGCACGA GGTGGAGGTGGTCATCAAGCACAACCGGTTCACAAAGGAGACCTATGACTTCGACATCGCCGTGCTCCGGCTCAAGACCCCCATCACCTT >In-frame_RNF19A_ENST00000341084_chr8_101299729_-_F10_ENST00000375551_chr13_113792771_+_1442nt ATGCAAGAACAAGAAATAGGTTTTATCTCTAAATATAATGAAGGGCTGTGTGTAAACACTGACCCTGTCTCAATTCTAACAAGCATTTTA GACATGAGTTTACATCGGCAAATGGGTTCAGATCGAGATCTTCAGTCCTCTGCTTCATCTGTGAGCTTGCCTTCAGTCAAAAAGGCACCC AAAAAAAGAAGAATTTCAATAGGCTCCCTGTTTCGGAGGAAAAAAGATAACAAACGTAAATCAAGGGAGCTAAATGGCGGGGTGGATGGA ATTGCAAGTATTGAAAGTATACATTCTGAAATGTGTACTGATAAGAACTCCATTTTCTCTACAAATACCTCTTCTGACAATGGATTAACT TCCATCAGCAAACAAATTGGAGACTTCATAGAGTGCCCTTTGTGCCTTTTGCGGCATTCTAAAGACAGATTTCCTGATATAATGACTTGT CATCACAGATCTTGTGTGGATTGCTTACGACAATATTTAAGGATAGAAATCTCTGAAAGCAGAGTTAATATTAGTTGCCCAGAATGTACT GAACGGTTTAATCCCCATGATATTCGCTTGATATTAAGTGATGATGTCTTGATGGAAAAATACGAAGAATTTATGCTTAGACGGTGGCTT GTTGCAGATCCTGATTGTAGGTGGTGTCCAGCTCCAGACTGTGGAATGAATTCTGGAATAAATACAAAGATGGCGACCAGTGTGAGACCA GTCCTTGCCAGAACCAGGGCAAATGTAAAGACGGCCTCGGGGAATACACCTGCACCTGTTTAGAAGGATTCGAAGGCAAAAACTGTGAAT TATTCACACGGAAGCTCTGCAGCCTGGACAACGGGGACTGTGACCAGTTCTGCCACGAGGAACAGAACTCTGTGGTGTGCTCCTGCGCCC GCGGGTACACCCTGGCTGACAACGGCAAGGCCTGCATTCCCACAGGGCCCTACCCCTGTGGGAAACAGACCCTGGAACGCAGGAAGAGGT CAGTGGCCCAGGCCACCAGCAGCAGCGGGGAGGCCCCTGACAGCATCACATGGAAGCCATATGATGCAGCCGACCTGGACCCCACCGAGA ACCCCTTCGACCTGCTTGACTTCAACCAGACGCAGCCTGAGAGGGGCGACAACAACCTCACCAGGATCGTGGGAGGCCAGGAATGCAAGG ACGGGGAGTGTCCCTGGCAGGCCCTGCTCATCAATGAGGAAAACGAGGGTTTCTGTGGTGGAACCATTCTGAGCGAGTTCTACATCCTAA CGGCAGCCCACTGTCTCTACCAAGCCAAGAGATTCAAGGGGACCGGAACACGGAGCAGGAGGAGGGCGGTGAGGCGGTGCACGAGGTGGA GGTGGTCATCAAGCACAACCGGTTCACAAAGGAGACCTATGACTTCGACATCGCCGTGCTCCGGCTCAAGACCCCCATCACCTTCCGCAT >In-frame_RNF19A_ENST00000341084_chr8_101299729_-_F10_ENST00000375559_chr13_113792771_+_1910nt ATGCAAGAACAAGAAATAGGTTTTATCTCTAAATATAATGAAGGGCTGTGTGTAAACACTGACCCTGTCTCAATTCTAACAAGCATTTTA GACATGAGTTTACATCGGCAAATGGGTTCAGATCGAGATCTTCAGTCCTCTGCTTCATCTGTGAGCTTGCCTTCAGTCAAAAAGGCACCC AAAAAAAGAAGAATTTCAATAGGCTCCCTGTTTCGGAGGAAAAAAGATAACAAACGTAAATCAAGGGAGCTAAATGGCGGGGTGGATGGA ATTGCAAGTATTGAAAGTATACATTCTGAAATGTGTACTGATAAGAACTCCATTTTCTCTACAAATACCTCTTCTGACAATGGATTAACT TCCATCAGCAAACAAATTGGAGACTTCATAGAGTGCCCTTTGTGCCTTTTGCGGCATTCTAAAGACAGATTTCCTGATATAATGACTTGT CATCACAGATCTTGTGTGGATTGCTTACGACAATATTTAAGGATAGAAATCTCTGAAAGCAGAGTTAATATTAGTTGCCCAGAATGTACT GAACGGTTTAATCCCCATGATATTCGCTTGATATTAAGTGATGATGTCTTGATGGAAAAATACGAAGAATTTATGCTTAGACGGTGGCTT GTTGCAGATCCTGATTGTAGGTGGTGTCCAGCTCCAGACTGTGGAATGAATTCTGGAATAAATACAAAGATGGCGACCAGTGTGAGACCA GTCCTTGCCAGAACCAGGGCAAATGTAAAGACGGCCTCGGGGAATACACCTGCACCTGTTTAGAAGGATTCGAAGGCAAAAACTGTGAAT TATTCACACGGAAGCTCTGCAGCCTGGACAACGGGGACTGTGACCAGTTCTGCCACGAGGAACAGAACTCTGTGGTGTGCTCCTGCGCCC GCGGGTACACCCTGGCTGACAACGGCAAGGCCTGCATTCCCACAGGGCCCTACCCCTGTGGGAAACAGACCCTGGAACGCAGGAAGAGGT CAGTGGCCCAGGCCACCAGCAGCAGCGGGGAGGCCCCTGACAGCATCACATGGAAGCCATATGATGCAGCCGACCTGGACCCCACCGAGA ACCCCTTCGACCTGCTTGACTTCAACCAGACGCAGCCTGAGAGGGGCGACAACAACCTCACCAGGATCGTGGGAGGCCAGGAATGCAAGG ACGGGGAGTGTCCCTGGCAGGCCCTGCTCATCAATGAGGAAAACGAGGGTTTCTGTGGTGGAACCATTCTGAGCGAGTTCTACATCCTAA CGGCAGCCCACTGTCTCTACCAAGCCAAGAGATTCAAGGTGAGGGTAGGGGACCGGAACACGGAGCAGGAGGAGGGCGGTGAGGCGGTGC ACGAGGTGGAGGTGGTCATCAAGCACAACCGGTTCACAAAGGAGACCTATGACTTCGACATCGCCGTGCTCCGGCTCAAGACCCCCATCA CCTTCCGCATGAACGTGGCGCCTGCCTGCCTCCCCGAGCGTGACTGGGCCGAGTCCACGCTGATGACGCAGAAGACGGGGATTGTGAGCG GCTTCGGGCGCACCCACGAGAAGGGCCGGCAGTCCACCAGGCTCAAGATGCTGGAGGTGCCCTACGTGGACCGCAACAGCTGCAAGCTGT CCAGCAGCTTCATCATCACCCAGAACATGTTCTGTGCCGGCTACGACACCAAGCAGGAGGATGCCTGCCAGGGGGACAGCGGGGGCCCGC ACGTCACCCGCTTCAAGGACACCTACTTCGTGACAGGCATCGTCAGCTGGGGAGAGGGCTGTGCCCGTAAGGGGAAGTACGGGATCTACA CCAAGGTCACCGCCTTCCTCAAGTGGATCGACAGGTCCATGAAAACCAGGGGCTTGCCCAAGGCCAAGAGCCATGCCCCGGAGGTCATAA >In-frame_RNF19A_ENST00000519449_chr8_101299729_-_F10_ENST00000409306_chr13_113792771_+_1448nt ATGCAAGAACAAGAAATAGGTTTTATCTCTAAATATAATGAAGGGCTGTGTGTAAACACTGACCCTGTCTCAATTCTAACAAGCATTTTA GACATGAGTTTACATCGGCAAATGGGTTCAGATCGAGATCTTCAGTCCTCTGCTTCATCTGTGAGCTTGCCTTCAGTCAAAAAGGCACCC AAAAAAAGAAGAATTTCAATAGGCTCCCTGTTTCGGAGGAAAAAAGATAACAAACGTAAATCAAGGGAGCTAAATGGCGGGGTGGATGGA ATTGCAAGTATTGAAAGTATACATTCTGAAATGTGTACTGATAAGAACTCCATTTTCTCTACAAATACCTCTTCTGACAATGGATTAACT TCCATCAGCAAACAAATTGGAGACTTCATAGAGTGCCCTTTGTGCCTTTTGCGGCATTCTAAAGACAGATTTCCTGATATAATGACTTGT CATCACAGATCTTGTGTGGATTGCTTACGACAATATTTAAGGATAGAAATCTCTGAAAGCAGAGTTAATATTAGTTGCCCAGAATGTACT GAACGGTTTAATCCCCATGATATTCGCTTGATATTAAGTGATGATGTCTTGATGGAAAAATACGAAGAATTTATGCTTAGACGGTGGCTT GTTGCAGATCCTGATTGTAGGTGGTGTCCAGCTCCAGACTGTGGAATGAATTCTGGAATAAATACAAAGATGGCGACCAGTGTGAGACCA GTCCTTGCCAGAACCAGGGCAAATGTAAAGACGGCCTCGGGGAATACACCTGCACCTGTTTAGAAGGATTCGAAGGCAAAAACTGTGAAT TATTCACACGGAAGCTCTGCAGCCTGGACAACGGGGACTGTGACCAGTTCTGCCACGAGGAACAGAACTCTGTGGTGTGCTCCTGCGCCC GCGGGTACACCCTGGCTGACAACGGCAAGGCCTGCATTCCCACAGGGCCCTACCCCTGTGGGAAACAGACCCTGGAACGCAGGAAGAGGT CAGTGGCCCAGGCCACCAGCAGCAGCGGGGAGGCCCCTGACAGCATCACATGGAAGCCATATGATGCAGCCGACCTGGACCCCACCGAGA ACCCCTTCGACCTGCTTGACTTCAACCAGACGCAGCCTGAGAGGGGCGACAACAACCTCACCAGGATCGTGGGAGGCCAGGAATGCAAGG ACGGGGAGTGTCCCTGGCAGGCCCTGCTCATCAATGAGGAAAACGAGGGTTTCTGTGGTGGAACCATTCTGAGCGAGTTCTACATCCTAA CGGCAGCCCACTGTCTCTACCAAGCCAAGAGATTCAAGGTGAGGGGGACCGGAACACGGAGCAGGAGGAGGGCGGTGAGGCGGTGCACGA GGTGGAGGTGGTCATCAAGCACAACCGGTTCACAAAGGAGACCTATGACTTCGACATCGCCGTGCTCCGGCTCAAGACCCCCATCACCTT >In-frame_RNF19A_ENST00000519449_chr8_101299729_-_F10_ENST00000375551_chr13_113792771_+_1442nt ATGCAAGAACAAGAAATAGGTTTTATCTCTAAATATAATGAAGGGCTGTGTGTAAACACTGACCCTGTCTCAATTCTAACAAGCATTTTA GACATGAGTTTACATCGGCAAATGGGTTCAGATCGAGATCTTCAGTCCTCTGCTTCATCTGTGAGCTTGCCTTCAGTCAAAAAGGCACCC AAAAAAAGAAGAATTTCAATAGGCTCCCTGTTTCGGAGGAAAAAAGATAACAAACGTAAATCAAGGGAGCTAAATGGCGGGGTGGATGGA ATTGCAAGTATTGAAAGTATACATTCTGAAATGTGTACTGATAAGAACTCCATTTTCTCTACAAATACCTCTTCTGACAATGGATTAACT TCCATCAGCAAACAAATTGGAGACTTCATAGAGTGCCCTTTGTGCCTTTTGCGGCATTCTAAAGACAGATTTCCTGATATAATGACTTGT CATCACAGATCTTGTGTGGATTGCTTACGACAATATTTAAGGATAGAAATCTCTGAAAGCAGAGTTAATATTAGTTGCCCAGAATGTACT GAACGGTTTAATCCCCATGATATTCGCTTGATATTAAGTGATGATGTCTTGATGGAAAAATACGAAGAATTTATGCTTAGACGGTGGCTT GTTGCAGATCCTGATTGTAGGTGGTGTCCAGCTCCAGACTGTGGAATGAATTCTGGAATAAATACAAAGATGGCGACCAGTGTGAGACCA GTCCTTGCCAGAACCAGGGCAAATGTAAAGACGGCCTCGGGGAATACACCTGCACCTGTTTAGAAGGATTCGAAGGCAAAAACTGTGAAT TATTCACACGGAAGCTCTGCAGCCTGGACAACGGGGACTGTGACCAGTTCTGCCACGAGGAACAGAACTCTGTGGTGTGCTCCTGCGCCC GCGGGTACACCCTGGCTGACAACGGCAAGGCCTGCATTCCCACAGGGCCCTACCCCTGTGGGAAACAGACCCTGGAACGCAGGAAGAGGT CAGTGGCCCAGGCCACCAGCAGCAGCGGGGAGGCCCCTGACAGCATCACATGGAAGCCATATGATGCAGCCGACCTGGACCCCACCGAGA ACCCCTTCGACCTGCTTGACTTCAACCAGACGCAGCCTGAGAGGGGCGACAACAACCTCACCAGGATCGTGGGAGGCCAGGAATGCAAGG ACGGGGAGTGTCCCTGGCAGGCCCTGCTCATCAATGAGGAAAACGAGGGTTTCTGTGGTGGAACCATTCTGAGCGAGTTCTACATCCTAA CGGCAGCCCACTGTCTCTACCAAGCCAAGAGATTCAAGGGGACCGGAACACGGAGCAGGAGGAGGGCGGTGAGGCGGTGCACGAGGTGGA GGTGGTCATCAAGCACAACCGGTTCACAAAGGAGACCTATGACTTCGACATCGCCGTGCTCCGGCTCAAGACCCCCATCACCTTCCGCAT >In-frame_RNF19A_ENST00000519449_chr8_101299729_-_F10_ENST00000375559_chr13_113792771_+_1910nt ATGCAAGAACAAGAAATAGGTTTTATCTCTAAATATAATGAAGGGCTGTGTGTAAACACTGACCCTGTCTCAATTCTAACAAGCATTTTA GACATGAGTTTACATCGGCAAATGGGTTCAGATCGAGATCTTCAGTCCTCTGCTTCATCTGTGAGCTTGCCTTCAGTCAAAAAGGCACCC AAAAAAAGAAGAATTTCAATAGGCTCCCTGTTTCGGAGGAAAAAAGATAACAAACGTAAATCAAGGGAGCTAAATGGCGGGGTGGATGGA ATTGCAAGTATTGAAAGTATACATTCTGAAATGTGTACTGATAAGAACTCCATTTTCTCTACAAATACCTCTTCTGACAATGGATTAACT TCCATCAGCAAACAAATTGGAGACTTCATAGAGTGCCCTTTGTGCCTTTTGCGGCATTCTAAAGACAGATTTCCTGATATAATGACTTGT CATCACAGATCTTGTGTGGATTGCTTACGACAATATTTAAGGATAGAAATCTCTGAAAGCAGAGTTAATATTAGTTGCCCAGAATGTACT GAACGGTTTAATCCCCATGATATTCGCTTGATATTAAGTGATGATGTCTTGATGGAAAAATACGAAGAATTTATGCTTAGACGGTGGCTT GTTGCAGATCCTGATTGTAGGTGGTGTCCAGCTCCAGACTGTGGAATGAATTCTGGAATAAATACAAAGATGGCGACCAGTGTGAGACCA GTCCTTGCCAGAACCAGGGCAAATGTAAAGACGGCCTCGGGGAATACACCTGCACCTGTTTAGAAGGATTCGAAGGCAAAAACTGTGAAT TATTCACACGGAAGCTCTGCAGCCTGGACAACGGGGACTGTGACCAGTTCTGCCACGAGGAACAGAACTCTGTGGTGTGCTCCTGCGCCC GCGGGTACACCCTGGCTGACAACGGCAAGGCCTGCATTCCCACAGGGCCCTACCCCTGTGGGAAACAGACCCTGGAACGCAGGAAGAGGT CAGTGGCCCAGGCCACCAGCAGCAGCGGGGAGGCCCCTGACAGCATCACATGGAAGCCATATGATGCAGCCGACCTGGACCCCACCGAGA ACCCCTTCGACCTGCTTGACTTCAACCAGACGCAGCCTGAGAGGGGCGACAACAACCTCACCAGGATCGTGGGAGGCCAGGAATGCAAGG ACGGGGAGTGTCCCTGGCAGGCCCTGCTCATCAATGAGGAAAACGAGGGTTTCTGTGGTGGAACCATTCTGAGCGAGTTCTACATCCTAA CGGCAGCCCACTGTCTCTACCAAGCCAAGAGATTCAAGGTGAGGGTAGGGGACCGGAACACGGAGCAGGAGGAGGGCGGTGAGGCGGTGC ACGAGGTGGAGGTGGTCATCAAGCACAACCGGTTCACAAAGGAGACCTATGACTTCGACATCGCCGTGCTCCGGCTCAAGACCCCCATCA CCTTCCGCATGAACGTGGCGCCTGCCTGCCTCCCCGAGCGTGACTGGGCCGAGTCCACGCTGATGACGCAGAAGACGGGGATTGTGAGCG GCTTCGGGCGCACCCACGAGAAGGGCCGGCAGTCCACCAGGCTCAAGATGCTGGAGGTGCCCTACGTGGACCGCAACAGCTGCAAGCTGT CCAGCAGCTTCATCATCACCCAGAACATGTTCTGTGCCGGCTACGACACCAAGCAGGAGGATGCCTGCCAGGGGGACAGCGGGGGCCCGC ACGTCACCCGCTTCAAGGACACCTACTTCGTGACAGGCATCGTCAGCTGGGGAGAGGGCTGTGCCCGTAAGGGGAAGTACGGGATCTACA CCAAGGTCACCGCCTTCCTCAAGTGGATCGACAGGTCCATGAAAACCAGGGGCTTGCCCAAGGCCAAGAGCCATGCCCCGGAGGTCATAA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_RNF19A_ENST00000341084_chr8_101299729_-_F10_ENST00000409306_chr13_113792771_+_2405nt GGGGGCCGCAGTCGGGGCCACCCGGGTGCAGCGGGGCGGCTCCTGCGCGGGCGCGGAACGAACGTGCGCAAGGGAACAGCCGCGTCCAGA GCCGCCCGCAGCGGGCCCGGTGGGCGTGACGCCATGACGCACAGCACGCGGGCGGCGCGCTGGGGCGGGGCGGCCGGGGGCGGGAGGAAG AAGTGGGAGGAGGAGGAGGGGAAAGCGGGGGCTGCGGGAGGGGGAGGTGGTAGTTGCGGCGCTGGTTCCCGGGAGCAGCCGTCGAGCCAC AACTGCGGAGGAGGAGTTCGGGAAAGCGGCCGTCGGGACTCCTCCCCTCCGTCGTCTCCGCCCCGGTTGAGAGGCGCCTCGGCGCATCGG AGGGACCCTCCCCCGCGCTTCCTCAGGCTGCTGTCGCCGCTGCTGGGAGATGGGCCTACTCGCCCGCCACCCTGCGCTGCCGCCGCTCTG AGGAGTTAAAGAACATCCATGATAGCAGTCTTCTGTAAATCGAACTTTTCAAGAATTCTCTGAAGGAACCAAGTAGGATATTCTTACATC ATGACTTAATGTGAATGCAAGAACAAGAAATAGGTTTTATCTCTAAATATAATGAAGGGCTGTGTGTAAACACTGACCCTGTCTCAATTC TAACAAGCATTTTAGACATGAGTTTACATCGGCAAATGGGTTCAGATCGAGATCTTCAGTCCTCTGCTTCATCTGTGAGCTTGCCTTCAG TCAAAAAGGCACCCAAAAAAAGAAGAATTTCAATAGGCTCCCTGTTTCGGAGGAAAAAAGATAACAAACGTAAATCAAGGGAGCTAAATG GCGGGGTGGATGGAATTGCAAGTATTGAAAGTATACATTCTGAAATGTGTACTGATAAGAACTCCATTTTCTCTACAAATACCTCTTCTG ACAATGGATTAACTTCCATCAGCAAACAAATTGGAGACTTCATAGAGTGCCCTTTGTGCCTTTTGCGGCATTCTAAAGACAGATTTCCTG ATATAATGACTTGTCATCACAGATCTTGTGTGGATTGCTTACGACAATATTTAAGGATAGAAATCTCTGAAAGCAGAGTTAATATTAGTT GCCCAGAATGTACTGAACGGTTTAATCCCCATGATATTCGCTTGATATTAAGTGATGATGTCTTGATGGAAAAATACGAAGAATTTATGC TTAGACGGTGGCTTGTTGCAGATCCTGATTGTAGGTGGTGTCCAGCTCCAGACTGTGGAATGAATTCTGGAATAAATACAAAGATGGCGA CCAGTGTGAGACCAGTCCTTGCCAGAACCAGGGCAAATGTAAAGACGGCCTCGGGGAATACACCTGCACCTGTTTAGAAGGATTCGAAGG CAAAAACTGTGAATTATTCACACGGAAGCTCTGCAGCCTGGACAACGGGGACTGTGACCAGTTCTGCCACGAGGAACAGAACTCTGTGGT GTGCTCCTGCGCCCGCGGGTACACCCTGGCTGACAACGGCAAGGCCTGCATTCCCACAGGGCCCTACCCCTGTGGGAAACAGACCCTGGA ACGCAGGAAGAGGTCAGTGGCCCAGGCCACCAGCAGCAGCGGGGAGGCCCCTGACAGCATCACATGGAAGCCATATGATGCAGCCGACCT GGACCCCACCGAGAACCCCTTCGACCTGCTTGACTTCAACCAGACGCAGCCTGAGAGGGGCGACAACAACCTCACCAGGATCGTGGGAGG CCAGGAATGCAAGGACGGGGAGTGTCCCTGGCAGGCCCTGCTCATCAATGAGGAAAACGAGGGTTTCTGTGGTGGAACCATTCTGAGCGA GTTCTACATCCTAACGGCAGCCCACTGTCTCTACCAAGCCAAGAGATTCAAGGTGAGGGGGACCGGAACACGGAGCAGGAGGAGGGCGGT GAGGCGGTGCACGAGGTGGAGGTGGTCATCAAGCACAACCGGTTCACAAAGGAGACCTATGACTTCGACATCGCCGTGCTCCGGCTCAAG ACCCCCATCACCTTCCGCATGAACGTGGCGCCTGCCTGCCTCCCCGAGCGTGACTGGGCCGAGTCCACGCTGATGACGCAGAAGACGGGG ATTGTGAGCGGCTTCGGGCGCACCCACGAGAAGGGCCGGCAGTCCACCAGGCTCAAGATGCTGGAGGTGCCCTACGTGGACCGCAACAGC TGCAAGCTGTCCAGCAGCTTCATCATCACCCAGAACATGTTCTGTGCCGGCTACGACACCAAGCAGGAGGATGCCTGCCAGGGGGACAGC GGGGGCCCGCACGTCACCCGCTTCAAGGACACCTACTTCGTGACAGGCATCGTCAGCTGGGGAGAGGGCTGTGCCCGTAAGGGGAAGTAC >In-frame_RNF19A_ENST00000341084_chr8_101299729_-_F10_ENST00000375551_chr13_113792771_+_2464nt GGGGGCCGCAGTCGGGGCCACCCGGGTGCAGCGGGGCGGCTCCTGCGCGGGCGCGGAACGAACGTGCGCAAGGGAACAGCCGCGTCCAGA GCCGCCCGCAGCGGGCCCGGTGGGCGTGACGCCATGACGCACAGCACGCGGGCGGCGCGCTGGGGCGGGGCGGCCGGGGGCGGGAGGAAG AAGTGGGAGGAGGAGGAGGGGAAAGCGGGGGCTGCGGGAGGGGGAGGTGGTAGTTGCGGCGCTGGTTCCCGGGAGCAGCCGTCGAGCCAC AACTGCGGAGGAGGAGTTCGGGAAAGCGGCCGTCGGGACTCCTCCCCTCCGTCGTCTCCGCCCCGGTTGAGAGGCGCCTCGGCGCATCGG AGGGACCCTCCCCCGCGCTTCCTCAGGCTGCTGTCGCCGCTGCTGGGAGATGGGCCTACTCGCCCGCCACCCTGCGCTGCCGCCGCTCTG AGGAGTTAAAGAACATCCATGATAGCAGTCTTCTGTAAATCGAACTTTTCAAGAATTCTCTGAAGGAACCAAGTAGGATATTCTTACATC ATGACTTAATGTGAATGCAAGAACAAGAAATAGGTTTTATCTCTAAATATAATGAAGGGCTGTGTGTAAACACTGACCCTGTCTCAATTC TAACAAGCATTTTAGACATGAGTTTACATCGGCAAATGGGTTCAGATCGAGATCTTCAGTCCTCTGCTTCATCTGTGAGCTTGCCTTCAG TCAAAAAGGCACCCAAAAAAAGAAGAATTTCAATAGGCTCCCTGTTTCGGAGGAAAAAAGATAACAAACGTAAATCAAGGGAGCTAAATG GCGGGGTGGATGGAATTGCAAGTATTGAAAGTATACATTCTGAAATGTGTACTGATAAGAACTCCATTTTCTCTACAAATACCTCTTCTG ACAATGGATTAACTTCCATCAGCAAACAAATTGGAGACTTCATAGAGTGCCCTTTGTGCCTTTTGCGGCATTCTAAAGACAGATTTCCTG ATATAATGACTTGTCATCACAGATCTTGTGTGGATTGCTTACGACAATATTTAAGGATAGAAATCTCTGAAAGCAGAGTTAATATTAGTT GCCCAGAATGTACTGAACGGTTTAATCCCCATGATATTCGCTTGATATTAAGTGATGATGTCTTGATGGAAAAATACGAAGAATTTATGC TTAGACGGTGGCTTGTTGCAGATCCTGATTGTAGGTGGTGTCCAGCTCCAGACTGTGGAATGAATTCTGGAATAAATACAAAGATGGCGA CCAGTGTGAGACCAGTCCTTGCCAGAACCAGGGCAAATGTAAAGACGGCCTCGGGGAATACACCTGCACCTGTTTAGAAGGATTCGAAGG CAAAAACTGTGAATTATTCACACGGAAGCTCTGCAGCCTGGACAACGGGGACTGTGACCAGTTCTGCCACGAGGAACAGAACTCTGTGGT GTGCTCCTGCGCCCGCGGGTACACCCTGGCTGACAACGGCAAGGCCTGCATTCCCACAGGGCCCTACCCCTGTGGGAAACAGACCCTGGA ACGCAGGAAGAGGTCAGTGGCCCAGGCCACCAGCAGCAGCGGGGAGGCCCCTGACAGCATCACATGGAAGCCATATGATGCAGCCGACCT GGACCCCACCGAGAACCCCTTCGACCTGCTTGACTTCAACCAGACGCAGCCTGAGAGGGGCGACAACAACCTCACCAGGATCGTGGGAGG CCAGGAATGCAAGGACGGGGAGTGTCCCTGGCAGGCCCTGCTCATCAATGAGGAAAACGAGGGTTTCTGTGGTGGAACCATTCTGAGCGA GTTCTACATCCTAACGGCAGCCCACTGTCTCTACCAAGCCAAGAGATTCAAGGGGACCGGAACACGGAGCAGGAGGAGGGCGGTGAGGCG GTGCACGAGGTGGAGGTGGTCATCAAGCACAACCGGTTCACAAAGGAGACCTATGACTTCGACATCGCCGTGCTCCGGCTCAAGACCCCC ATCACCTTCCGCATGAACGTGGCGCCTGCCTGCCTCCCCGAGCGTGACTGGGCCGAGTCCACGCTGATGACGCAGAAGACGGGGATTGTG AGCGGCTTCGGGCGCACCCACGAGAAGGGCCGGCAGTCCACCAGGCTCAAGATGCTGGAGGTGCCCTACGTGGACCGCAACAGCTGCAAG CTGTCCAGCAGCTTCATCATCACCCAGAACATGTTCTGTGCCGGCTACGACACCAAGCAGGAGGATGCCTGCCAGGGGGACAGCGGGGGC CCGCACGTCACCCGCTTCAAGGACACCTACTTCGTGACAGGCATCGTCAGCTGGGGAGAGGGCTGTGCCCGTAAGGGGAAGTACGGGATC TACACCAAGGTCACCGCCTTCCTCAAGTGGATCGACAGGTCCATGAAAACCAGGGGCTTGCCCAAGGCCAAGAGCCATGCCCCGGAGGTC >In-frame_RNF19A_ENST00000341084_chr8_101299729_-_F10_ENST00000375559_chr13_113792771_+_2476nt GGGGGCCGCAGTCGGGGCCACCCGGGTGCAGCGGGGCGGCTCCTGCGCGGGCGCGGAACGAACGTGCGCAAGGGAACAGCCGCGTCCAGA GCCGCCCGCAGCGGGCCCGGTGGGCGTGACGCCATGACGCACAGCACGCGGGCGGCGCGCTGGGGCGGGGCGGCCGGGGGCGGGAGGAAG AAGTGGGAGGAGGAGGAGGGGAAAGCGGGGGCTGCGGGAGGGGGAGGTGGTAGTTGCGGCGCTGGTTCCCGGGAGCAGCCGTCGAGCCAC AACTGCGGAGGAGGAGTTCGGGAAAGCGGCCGTCGGGACTCCTCCCCTCCGTCGTCTCCGCCCCGGTTGAGAGGCGCCTCGGCGCATCGG AGGGACCCTCCCCCGCGCTTCCTCAGGCTGCTGTCGCCGCTGCTGGGAGATGGGCCTACTCGCCCGCCACCCTGCGCTGCCGCCGCTCTG AGGAGTTAAAGAACATCCATGATAGCAGTCTTCTGTAAATCGAACTTTTCAAGAATTCTCTGAAGGAACCAAGTAGGATATTCTTACATC ATGACTTAATGTGAATGCAAGAACAAGAAATAGGTTTTATCTCTAAATATAATGAAGGGCTGTGTGTAAACACTGACCCTGTCTCAATTC TAACAAGCATTTTAGACATGAGTTTACATCGGCAAATGGGTTCAGATCGAGATCTTCAGTCCTCTGCTTCATCTGTGAGCTTGCCTTCAG TCAAAAAGGCACCCAAAAAAAGAAGAATTTCAATAGGCTCCCTGTTTCGGAGGAAAAAAGATAACAAACGTAAATCAAGGGAGCTAAATG GCGGGGTGGATGGAATTGCAAGTATTGAAAGTATACATTCTGAAATGTGTACTGATAAGAACTCCATTTTCTCTACAAATACCTCTTCTG ACAATGGATTAACTTCCATCAGCAAACAAATTGGAGACTTCATAGAGTGCCCTTTGTGCCTTTTGCGGCATTCTAAAGACAGATTTCCTG ATATAATGACTTGTCATCACAGATCTTGTGTGGATTGCTTACGACAATATTTAAGGATAGAAATCTCTGAAAGCAGAGTTAATATTAGTT GCCCAGAATGTACTGAACGGTTTAATCCCCATGATATTCGCTTGATATTAAGTGATGATGTCTTGATGGAAAAATACGAAGAATTTATGC TTAGACGGTGGCTTGTTGCAGATCCTGATTGTAGGTGGTGTCCAGCTCCAGACTGTGGAATGAATTCTGGAATAAATACAAAGATGGCGA CCAGTGTGAGACCAGTCCTTGCCAGAACCAGGGCAAATGTAAAGACGGCCTCGGGGAATACACCTGCACCTGTTTAGAAGGATTCGAAGG CAAAAACTGTGAATTATTCACACGGAAGCTCTGCAGCCTGGACAACGGGGACTGTGACCAGTTCTGCCACGAGGAACAGAACTCTGTGGT GTGCTCCTGCGCCCGCGGGTACACCCTGGCTGACAACGGCAAGGCCTGCATTCCCACAGGGCCCTACCCCTGTGGGAAACAGACCCTGGA ACGCAGGAAGAGGTCAGTGGCCCAGGCCACCAGCAGCAGCGGGGAGGCCCCTGACAGCATCACATGGAAGCCATATGATGCAGCCGACCT GGACCCCACCGAGAACCCCTTCGACCTGCTTGACTTCAACCAGACGCAGCCTGAGAGGGGCGACAACAACCTCACCAGGATCGTGGGAGG CCAGGAATGCAAGGACGGGGAGTGTCCCTGGCAGGCCCTGCTCATCAATGAGGAAAACGAGGGTTTCTGTGGTGGAACCATTCTGAGCGA GTTCTACATCCTAACGGCAGCCCACTGTCTCTACCAAGCCAAGAGATTCAAGGTGAGGGTAGGGGACCGGAACACGGAGCAGGAGGAGGG CGGTGAGGCGGTGCACGAGGTGGAGGTGGTCATCAAGCACAACCGGTTCACAAAGGAGACCTATGACTTCGACATCGCCGTGCTCCGGCT CAAGACCCCCATCACCTTCCGCATGAACGTGGCGCCTGCCTGCCTCCCCGAGCGTGACTGGGCCGAGTCCACGCTGATGACGCAGAAGAC GGGGATTGTGAGCGGCTTCGGGCGCACCCACGAGAAGGGCCGGCAGTCCACCAGGCTCAAGATGCTGGAGGTGCCCTACGTGGACCGCAA CAGCTGCAAGCTGTCCAGCAGCTTCATCATCACCCAGAACATGTTCTGTGCCGGCTACGACACCAAGCAGGAGGATGCCTGCCAGGGGGA CAGCGGGGGCCCGCACGTCACCCGCTTCAAGGACACCTACTTCGTGACAGGCATCGTCAGCTGGGGAGAGGGCTGTGCCCGTAAGGGGAA GTACGGGATCTACACCAAGGTCACCGCCTTCCTCAAGTGGATCGACAGGTCCATGAAAACCAGGGGCTTGCCCAAGGCCAAGAGCCATGC >In-frame_RNF19A_ENST00000519449_chr8_101299729_-_F10_ENST00000409306_chr13_113792771_+_2168nt ATAGTCACCAGAAGCTGGAAGAGTCAAAGGACACATTCTCCCCTCAAGCCCCAGTGGGAGCACGGCCCAGCTGGATTTTGGACTTCTGGC CTCCAGAACTAGACAGGGCCTCACTGTGTCACCCAGGGTGGAATACAGTGGTGTGATCATAGCTCACTGCAGCCTGGAATTCCTGGGCTC AAGCAACCCTGCCACCTCAGCCTTCCAAGTAGCTAGGACTACAGAACATCCATGATAGCAGTCTTCTGTAAATCGAACTTTTCAAGAATT CTCTGAAGGAACCAAGTAGGATATTCTTACATCATGACTTAATGTGAATGCAAGAACAAGAAATAGGTTTTATCTCTAAATATAATGAAG GGCTGTGTGTAAACACTGACCCTGTCTCAATTCTAACAAGCATTTTAGACATGAGTTTACATCGGCAAATGGGTTCAGATCGAGATCTTC AGTCCTCTGCTTCATCTGTGAGCTTGCCTTCAGTCAAAAAGGCACCCAAAAAAAGAAGAATTTCAATAGGCTCCCTGTTTCGGAGGAAAA AAGATAACAAACGTAAATCAAGGGAGCTAAATGGCGGGGTGGATGGAATTGCAAGTATTGAAAGTATACATTCTGAAATGTGTACTGATA AGAACTCCATTTTCTCTACAAATACCTCTTCTGACAATGGATTAACTTCCATCAGCAAACAAATTGGAGACTTCATAGAGTGCCCTTTGT GCCTTTTGCGGCATTCTAAAGACAGATTTCCTGATATAATGACTTGTCATCACAGATCTTGTGTGGATTGCTTACGACAATATTTAAGGA TAGAAATCTCTGAAAGCAGAGTTAATATTAGTTGCCCAGAATGTACTGAACGGTTTAATCCCCATGATATTCGCTTGATATTAAGTGATG ATGTCTTGATGGAAAAATACGAAGAATTTATGCTTAGACGGTGGCTTGTTGCAGATCCTGATTGTAGGTGGTGTCCAGCTCCAGACTGTG GAATGAATTCTGGAATAAATACAAAGATGGCGACCAGTGTGAGACCAGTCCTTGCCAGAACCAGGGCAAATGTAAAGACGGCCTCGGGGA ATACACCTGCACCTGTTTAGAAGGATTCGAAGGCAAAAACTGTGAATTATTCACACGGAAGCTCTGCAGCCTGGACAACGGGGACTGTGA CCAGTTCTGCCACGAGGAACAGAACTCTGTGGTGTGCTCCTGCGCCCGCGGGTACACCCTGGCTGACAACGGCAAGGCCTGCATTCCCAC AGGGCCCTACCCCTGTGGGAAACAGACCCTGGAACGCAGGAAGAGGTCAGTGGCCCAGGCCACCAGCAGCAGCGGGGAGGCCCCTGACAG CATCACATGGAAGCCATATGATGCAGCCGACCTGGACCCCACCGAGAACCCCTTCGACCTGCTTGACTTCAACCAGACGCAGCCTGAGAG GGGCGACAACAACCTCACCAGGATCGTGGGAGGCCAGGAATGCAAGGACGGGGAGTGTCCCTGGCAGGCCCTGCTCATCAATGAGGAAAA CGAGGGTTTCTGTGGTGGAACCATTCTGAGCGAGTTCTACATCCTAACGGCAGCCCACTGTCTCTACCAAGCCAAGAGATTCAAGGTGAG GGGGACCGGAACACGGAGCAGGAGGAGGGCGGTGAGGCGGTGCACGAGGTGGAGGTGGTCATCAAGCACAACCGGTTCACAAAGGAGACC TATGACTTCGACATCGCCGTGCTCCGGCTCAAGACCCCCATCACCTTCCGCATGAACGTGGCGCCTGCCTGCCTCCCCGAGCGTGACTGG GCCGAGTCCACGCTGATGACGCAGAAGACGGGGATTGTGAGCGGCTTCGGGCGCACCCACGAGAAGGGCCGGCAGTCCACCAGGCTCAAG ATGCTGGAGGTGCCCTACGTGGACCGCAACAGCTGCAAGCTGTCCAGCAGCTTCATCATCACCCAGAACATGTTCTGTGCCGGCTACGAC ACCAAGCAGGAGGATGCCTGCCAGGGGGACAGCGGGGGCCCGCACGTCACCCGCTTCAAGGACACCTACTTCGTGACAGGCATCGTCAGC TGGGGAGAGGGCTGTGCCCGTAAGGGGAAGTACGGGATCTACACCAAGGTCACCGCCTTCCTCAAGTGGATCGACAGGTCCATGAAAACC >In-frame_RNF19A_ENST00000519449_chr8_101299729_-_F10_ENST00000375551_chr13_113792771_+_2227nt ATAGTCACCAGAAGCTGGAAGAGTCAAAGGACACATTCTCCCCTCAAGCCCCAGTGGGAGCACGGCCCAGCTGGATTTTGGACTTCTGGC CTCCAGAACTAGACAGGGCCTCACTGTGTCACCCAGGGTGGAATACAGTGGTGTGATCATAGCTCACTGCAGCCTGGAATTCCTGGGCTC AAGCAACCCTGCCACCTCAGCCTTCCAAGTAGCTAGGACTACAGAACATCCATGATAGCAGTCTTCTGTAAATCGAACTTTTCAAGAATT CTCTGAAGGAACCAAGTAGGATATTCTTACATCATGACTTAATGTGAATGCAAGAACAAGAAATAGGTTTTATCTCTAAATATAATGAAG GGCTGTGTGTAAACACTGACCCTGTCTCAATTCTAACAAGCATTTTAGACATGAGTTTACATCGGCAAATGGGTTCAGATCGAGATCTTC AGTCCTCTGCTTCATCTGTGAGCTTGCCTTCAGTCAAAAAGGCACCCAAAAAAAGAAGAATTTCAATAGGCTCCCTGTTTCGGAGGAAAA AAGATAACAAACGTAAATCAAGGGAGCTAAATGGCGGGGTGGATGGAATTGCAAGTATTGAAAGTATACATTCTGAAATGTGTACTGATA AGAACTCCATTTTCTCTACAAATACCTCTTCTGACAATGGATTAACTTCCATCAGCAAACAAATTGGAGACTTCATAGAGTGCCCTTTGT GCCTTTTGCGGCATTCTAAAGACAGATTTCCTGATATAATGACTTGTCATCACAGATCTTGTGTGGATTGCTTACGACAATATTTAAGGA TAGAAATCTCTGAAAGCAGAGTTAATATTAGTTGCCCAGAATGTACTGAACGGTTTAATCCCCATGATATTCGCTTGATATTAAGTGATG ATGTCTTGATGGAAAAATACGAAGAATTTATGCTTAGACGGTGGCTTGTTGCAGATCCTGATTGTAGGTGGTGTCCAGCTCCAGACTGTG GAATGAATTCTGGAATAAATACAAAGATGGCGACCAGTGTGAGACCAGTCCTTGCCAGAACCAGGGCAAATGTAAAGACGGCCTCGGGGA ATACACCTGCACCTGTTTAGAAGGATTCGAAGGCAAAAACTGTGAATTATTCACACGGAAGCTCTGCAGCCTGGACAACGGGGACTGTGA CCAGTTCTGCCACGAGGAACAGAACTCTGTGGTGTGCTCCTGCGCCCGCGGGTACACCCTGGCTGACAACGGCAAGGCCTGCATTCCCAC AGGGCCCTACCCCTGTGGGAAACAGACCCTGGAACGCAGGAAGAGGTCAGTGGCCCAGGCCACCAGCAGCAGCGGGGAGGCCCCTGACAG CATCACATGGAAGCCATATGATGCAGCCGACCTGGACCCCACCGAGAACCCCTTCGACCTGCTTGACTTCAACCAGACGCAGCCTGAGAG GGGCGACAACAACCTCACCAGGATCGTGGGAGGCCAGGAATGCAAGGACGGGGAGTGTCCCTGGCAGGCCCTGCTCATCAATGAGGAAAA CGAGGGTTTCTGTGGTGGAACCATTCTGAGCGAGTTCTACATCCTAACGGCAGCCCACTGTCTCTACCAAGCCAAGAGATTCAAGGGGAC CGGAACACGGAGCAGGAGGAGGGCGGTGAGGCGGTGCACGAGGTGGAGGTGGTCATCAAGCACAACCGGTTCACAAAGGAGACCTATGAC TTCGACATCGCCGTGCTCCGGCTCAAGACCCCCATCACCTTCCGCATGAACGTGGCGCCTGCCTGCCTCCCCGAGCGTGACTGGGCCGAG TCCACGCTGATGACGCAGAAGACGGGGATTGTGAGCGGCTTCGGGCGCACCCACGAGAAGGGCCGGCAGTCCACCAGGCTCAAGATGCTG GAGGTGCCCTACGTGGACCGCAACAGCTGCAAGCTGTCCAGCAGCTTCATCATCACCCAGAACATGTTCTGTGCCGGCTACGACACCAAG CAGGAGGATGCCTGCCAGGGGGACAGCGGGGGCCCGCACGTCACCCGCTTCAAGGACACCTACTTCGTGACAGGCATCGTCAGCTGGGGA GAGGGCTGTGCCCGTAAGGGGAAGTACGGGATCTACACCAAGGTCACCGCCTTCCTCAAGTGGATCGACAGGTCCATGAAAACCAGGGGC >In-frame_RNF19A_ENST00000519449_chr8_101299729_-_F10_ENST00000375559_chr13_113792771_+_2239nt ATAGTCACCAGAAGCTGGAAGAGTCAAAGGACACATTCTCCCCTCAAGCCCCAGTGGGAGCACGGCCCAGCTGGATTTTGGACTTCTGGC CTCCAGAACTAGACAGGGCCTCACTGTGTCACCCAGGGTGGAATACAGTGGTGTGATCATAGCTCACTGCAGCCTGGAATTCCTGGGCTC AAGCAACCCTGCCACCTCAGCCTTCCAAGTAGCTAGGACTACAGAACATCCATGATAGCAGTCTTCTGTAAATCGAACTTTTCAAGAATT CTCTGAAGGAACCAAGTAGGATATTCTTACATCATGACTTAATGTGAATGCAAGAACAAGAAATAGGTTTTATCTCTAAATATAATGAAG GGCTGTGTGTAAACACTGACCCTGTCTCAATTCTAACAAGCATTTTAGACATGAGTTTACATCGGCAAATGGGTTCAGATCGAGATCTTC AGTCCTCTGCTTCATCTGTGAGCTTGCCTTCAGTCAAAAAGGCACCCAAAAAAAGAAGAATTTCAATAGGCTCCCTGTTTCGGAGGAAAA AAGATAACAAACGTAAATCAAGGGAGCTAAATGGCGGGGTGGATGGAATTGCAAGTATTGAAAGTATACATTCTGAAATGTGTACTGATA AGAACTCCATTTTCTCTACAAATACCTCTTCTGACAATGGATTAACTTCCATCAGCAAACAAATTGGAGACTTCATAGAGTGCCCTTTGT GCCTTTTGCGGCATTCTAAAGACAGATTTCCTGATATAATGACTTGTCATCACAGATCTTGTGTGGATTGCTTACGACAATATTTAAGGA TAGAAATCTCTGAAAGCAGAGTTAATATTAGTTGCCCAGAATGTACTGAACGGTTTAATCCCCATGATATTCGCTTGATATTAAGTGATG ATGTCTTGATGGAAAAATACGAAGAATTTATGCTTAGACGGTGGCTTGTTGCAGATCCTGATTGTAGGTGGTGTCCAGCTCCAGACTGTG GAATGAATTCTGGAATAAATACAAAGATGGCGACCAGTGTGAGACCAGTCCTTGCCAGAACCAGGGCAAATGTAAAGACGGCCTCGGGGA ATACACCTGCACCTGTTTAGAAGGATTCGAAGGCAAAAACTGTGAATTATTCACACGGAAGCTCTGCAGCCTGGACAACGGGGACTGTGA CCAGTTCTGCCACGAGGAACAGAACTCTGTGGTGTGCTCCTGCGCCCGCGGGTACACCCTGGCTGACAACGGCAAGGCCTGCATTCCCAC AGGGCCCTACCCCTGTGGGAAACAGACCCTGGAACGCAGGAAGAGGTCAGTGGCCCAGGCCACCAGCAGCAGCGGGGAGGCCCCTGACAG CATCACATGGAAGCCATATGATGCAGCCGACCTGGACCCCACCGAGAACCCCTTCGACCTGCTTGACTTCAACCAGACGCAGCCTGAGAG GGGCGACAACAACCTCACCAGGATCGTGGGAGGCCAGGAATGCAAGGACGGGGAGTGTCCCTGGCAGGCCCTGCTCATCAATGAGGAAAA CGAGGGTTTCTGTGGTGGAACCATTCTGAGCGAGTTCTACATCCTAACGGCAGCCCACTGTCTCTACCAAGCCAAGAGATTCAAGGTGAG GGTAGGGGACCGGAACACGGAGCAGGAGGAGGGCGGTGAGGCGGTGCACGAGGTGGAGGTGGTCATCAAGCACAACCGGTTCACAAAGGA GACCTATGACTTCGACATCGCCGTGCTCCGGCTCAAGACCCCCATCACCTTCCGCATGAACGTGGCGCCTGCCTGCCTCCCCGAGCGTGA CTGGGCCGAGTCCACGCTGATGACGCAGAAGACGGGGATTGTGAGCGGCTTCGGGCGCACCCACGAGAAGGGCCGGCAGTCCACCAGGCT CAAGATGCTGGAGGTGCCCTACGTGGACCGCAACAGCTGCAAGCTGTCCAGCAGCTTCATCATCACCCAGAACATGTTCTGTGCCGGCTA CGACACCAAGCAGGAGGATGCCTGCCAGGGGGACAGCGGGGGCCCGCACGTCACCCGCTTCAAGGACACCTACTTCGTGACAGGCATCGT CAGCTGGGGAGAGGGCTGTGCCCGTAAGGGGAAGTACGGGATCTACACCAAGGTCACCGCCTTCCTCAAGTGGATCGACAGGTCCATGAA |
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FusionGenePPI for RNF19A_F10 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| RNF19A | UBE2L3, UBE2L6, SOD1, CASR, VCP, SNCAIP, NUDT21, ILK, RPS6KA5, MAP3K7, C11orf58, ZAK | F10 | PRKAB1, SERPINB8, F7, F5, F8, PLAT, PLG, TFPI |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | RNF19A | chr8:101299729 | chr13:113792771 | ENST00000341084 | - | 2 | 10 | 660_838 | 224 | 839 | CASR |
| Hgene | RNF19A | chr8:101299729 | chr13:113792771 | ENST00000519449 | - | 3 | 11 | 660_838 | 224 | 839 | CASR |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for RNF19A_F10 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Tgene | F10 | P00742 | DB00036 | Coagulation factor VIIa Recombinant Human | Coagulation factor X | biotech | approved |
| Tgene | F10 | P00742 | DB01225 | Enoxaparin | Coagulation factor X | small molecule | approved |
| Tgene | F10 | P00742 | DB06228 | Rivaroxaban | Coagulation factor X | small molecule | approved |
| Tgene | F10 | P00742 | DB06605 | Apixaban | Coagulation factor X | small molecule | approved |
| Tgene | F10 | P00742 | DB13192 | Antihemophilic factor human | Coagulation factor X | biotech | approved |
| Tgene | F10 | P00742 | DB00025 | Antihemophilic factor, human recombinant | Coagulation factor X | biotech | approved|investigational |
| Tgene | F10 | P00742 | DB00100 | Coagulation Factor IX (Recombinant) | Coagulation factor X | biotech | approved|investigational |
| Tgene | F10 | P00742 | DB01109 | Heparin | Coagulation factor X | small molecule | approved|investigational |
| Tgene | F10 | P00742 | DB09258 | Bemiparin | Coagulation factor X | small molecule | approved|investigational |
| Tgene | F10 | P00742 | DB13151 | Anti-inhibitor coagulant complex | Coagulation factor X | biotech | approved|investigational |
| Tgene | F10 | P00742 | DB00170 | Menadione | Coagulation factor X | small molecule | approved|nutraceutical |
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RelatedDiseases for RNF19A_F10 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | F10 | C0015519 | Factor X Deficiency | 12 | CTD_human;HPO;ORPHANET;UNIPROT |
| Tgene | F10 | C0005779 | Blood Coagulation Disorders | 1 | CTD_human |
| Tgene | F10 | C0040053 | Thrombosis | 1 | CTD_human |
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