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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDrugs

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RelatedDiseases

Fusion gene ID: 31381

FusionGeneSummary for RNF114_PTPN1

check button Fusion gene summary
Fusion gene informationFusion gene name: RNF114_PTPN1
Fusion gene ID: 31381
HgeneTgene
Gene symbol

RNF114

PTPN1

Gene ID

55905

5770

Gene namering finger protein 114protein tyrosine phosphatase, non-receptor type 1
SynonymsPSORS12|ZNF313PTP1B
Cytomap

20q13.13

20q13.13

Type of geneprotein-codingprotein-coding
DescriptionE3 ubiquitin-protein ligase RNF114RING-type E3 ubiquitin transferase RNF114zinc finger protein 228zinc finger protein 313tyrosine-protein phosphatase non-receptor type 1protein tyrosine phosphatase, placentalprotein-tyrosine phosphatase 1B
Modification date2018051920180522
UniProtAcc

Q9Y508

P18031

Ensembl transtripts involved in fusion geneENST00000244061, ENST00000371621, 
ENST00000541713, 
Fusion gene scores* DoF score4 X 4 X 2=327 X 5 X 5=175
# samples 410
** MAII scorelog2(4/32*10)=0.321928094887362
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
log2(10/175*10)=-0.807354922057604
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: RNF114 [Title/Abstract] AND PTPN1 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationTumor suppressor gene involved fusion gene, in-frame but not retained their domain.
Tumor suppressor gene involved fusion gene, retained protein feature but frameshift.
DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgenePTPN1

GO:0030100

regulation of endocytosis

21135139

TgenePTPN1

GO:0030968

endoplasmic reticulum unfolded protein response

22169477

TgenePTPN1

GO:0035335

peptidyl-tyrosine dephosphorylation

21135139

TgenePTPN1

GO:0061098

positive regulation of protein tyrosine kinase activity

21216966

TgenePTPN1

GO:1903898

negative regulation of PERK-mediated unfolded protein response

21216966


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDBRCATCGA-AR-A0TQ-01ARNF114chr20

48565892

+PTPN1chr20

49177900

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000244061ENST00000371621RNF114chr20

48565892

+PTPN1chr20

49177900

+
5CDS-intronENST00000244061ENST00000541713RNF114chr20

48565892

+PTPN1chr20

49177900

+

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FusionProtFeatures for RNF114_PTPN1


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
RNF114

Q9Y508

PTPN1

P18031

E3 ubiquitin-protein ligase promoting the ubiquitinationand degradation of the CDK inhibitor CDKN1A and probably alsoCDKN1B and CDKN1C. These activities stimulate cell cycle's G1-to-Sphase transition and suppress cellular senescence. May play a rolein spermatogenesis. {ECO:0000269|PubMed:23645206}. Tyrosine-protein phosphatase which acts as a regulatorof endoplasmic reticulum unfolded protein response. Mediatesdephosphorylation of EIF2AK3/PERK; inactivating the protein kinaseactivity of EIF2AK3/PERK. May play an important role in CKII- andp60c-src-induced signal transduction cascades. May regulate theEFNA5-EPHA3 signaling pathway which modulates cell reorganizationand cell-cell repulsion. May also regulate the hepatocyte growthfactor receptor signaling pathway through dephosphorylation ofMET. {ECO:0000269|PubMed:18819921, ECO:0000269|PubMed:21135139,ECO:0000269|PubMed:22169477}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRNF114chr20:48565892chr20:49177900ENST00000244061+5629_68207229Zinc fingerRING-type
HgeneRNF114chr20:48565892chr20:49177900ENST00000244061+5691_110207229Zinc fingerC2HC RNF-type
TgenePTPN1chr20:48565892chr20:49177900ENST00000371621+010215_22121436RegionSubstrate binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgenePTPN1chr20:48565892chr20:49177900ENST00000371621+0103_27721436DomainTyrosine-protein phosphatase


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FusionGeneSequence for RNF114_PTPN1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_RNF114_ENST00000244061_chr20_48565892_+_PTPN1_ENST00000371621_chr20_49177900_+_622aa
MAAQQRDCGGAAQLAGPAAEADPLGRFTCPVCLEVYEKPVQVPCGHVFCSACLQECLKPKKPVCGVCRSALAPGVRAVELERQIESTETS
CHGCRKNFFLSKIRSHVATCSKYQNYIMEGVKATIKDASLQPRNVPNRYTFPCPYCPEKNFDQEGLVEHCKLFHSTDTKSVVCPICASMP
WGDPNYRSANFREHIQRRHRFSTDTFVDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDTINASLIKMEEAQRSYILT
QGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSTTTVRQLELENLTTQETREILHF
HTTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQTA
DQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHEDLEPPPEHIPPPPRPPKRILEPHNGKCREFFPNHQWVKEETQEDKDCPIKEEKGSPL


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_RNF114_ENST00000244061_chr20_48565892_+_PTPN1_ENST00000371621_chr20_49177900_+_1866nt
ATGGCGGCGCAACAGCGGGACTGCGGGGGTGCTGCGCAGCTGGCGGGGCCGGCGGCGGAGGCTGACCCCCTAGGACGCTTCACGTGTCCC
GTGTGCTTAGAGGTGTACGAGAAGCCGGTACAGGTGCCCTGCGGACACGTCTTTTGCTCTGCATGCCTGCAGGAATGTCTGAAGCCGAAG
AAGCCTGTCTGTGGGGTGTGTCGCAGCGCTCTGGCACCTGGCGTCCGAGCCGTGGAGCTCGAGCGGCAGATCGAGAGCACAGAGACTTCT
TGCCATGGCTGCCGTAAGAATTTCTTCCTGTCCAAGATCCGGTCCCACGTGGCTACTTGTTCCAAATACCAGAATTACATCATGGAAGGT
GTGAAGGCCACCATTAAGGATGCATCTCTTCAGCCAAGGAATGTTCCAAACCGTTACACCTTTCCTTGTCCTTACTGTCCTGAGAAGAAC
TTTGATCAGGAAGGACTTGTGGAACACTGCAAATTATTCCATAGCACGGATACCAAATCTGTGGTTTGTCCGATATGTGCCTCGATGCCC
TGGGGAGACCCCAACTACCGCAGCGCCAACTTCAGAGAGCACATCCAGCGCCGGCACCGGTTTTCTTATGACACTTTTGTGGATATCCGA
CATGAAGCCAGTGACTTCCCATGTAGAGTGGCCAAGCTTCCTAAGAACAAAAACCGAAATAGGTACAGAGACGTCAGTCCCTTTGACCAT
AGTCGGATTAAACTACATCAAGAAGATAATGACTATATCAACGCTAGTTTGATAAAAATGGAAGAAGCCCAAAGGAGTTACATTCTTACC
CAGGGCCCTTTGCCTAACACATGCGGTCACTTTTGGGAGATGGTGTGGGAGCAGAAAAGCAGGGGTGTCGTCATGCTCAACAGAGTGATG
GAGAAAGGTTCGTTAAAATGCGCACAATACTGGCCACAAAAAGAAGAAAAAGAGATGATCTTTGAAGACACAAATTTGAAATTAACATTG
ATCTCTGAAGATATCAAGTCATATTATACAGTGCGACAGCTAGAATTGGAAAACCTTACAACCCAAGAAACTCGAGAGATCTTACATTTC
CACTATACCACATGGCCTGACTTTGGAGTCCCTGAATCACCAGCCTCATTCTTGAACTTTCTTTTCAAAGTCCGAGAGTCAGGGTCACTC
AGCCCGGAGCACGGGCCCGTTGTGGTGCACTGCAGTGCAGGCATCGGCAGGTCTGGAACCTTCTGTCTGGCTGATACCTGCCTCTTGCTG
ATGGACAAGAGGAAAGACCCTTCTTCCGTTGATATCAAGAAAGTGCTGTTAGAAATGAGGAAGTTTCGGATGGGGCTGATCCAGACAGCC
GACCAGCTGCGCTTCTCCTACCTGGCTGTGATCGAAGGTGCCAAATTCATCATGGGGGACTCTTCCGTGCAGGATCAGTGGAAGGAGCTT
TCCCACGAGGACCTGGAGCCCCCACCCGAGCATATCCCCCCACCTCCCCGGCCACCCAAACGAATCCTGGAGCCACACAATGGGAAATGC
AGGGAGTTCTTCCCAAATCACCAGTGGGTGAAGGAAGAGACCCAGGAGGATAAAGACTGCCCCATCAAGGAAGAAAAAGGAAGCCCCTTA
AATGCCGCACCCTACGGCATCGAAAGCATGAGTCAAGACACTGAAGTTAGAAGTCGGGTCGTGGGGGGAAGTCTTCGAGGTGCCCAGGCT
GCCTCCCCAGCCAAAGGGGAGCCGTCACTGCCCGAGAAGGACGAGGACCATGCACTGAGTTACTGGAAGCCCTTCCTGGTCAACATGTGC


* Fusion transcript sequences (Full-length transcript).
>In-frame_RNF114_ENST00000244061_chr20_48565892_+_PTPN1_ENST00000371621_chr20_49177900_+_3915nt
AGATGGCGGCGCAACAGCGGGACTGCGGGGGTGCTGCGCAGCTGGCGGGGCCGGCGGCGGAGGCTGACCCCCTAGGACGCTTCACGTGTC
CCGTGTGCTTAGAGGTGTACGAGAAGCCGGTACAGGTGCCCTGCGGACACGTCTTTTGCTCTGCATGCCTGCAGGAATGTCTGAAGCCGA
AGAAGCCTGTCTGTGGGGTGTGTCGCAGCGCTCTGGCACCTGGCGTCCGAGCCGTGGAGCTCGAGCGGCAGATCGAGAGCACAGAGACTT
CTTGCCATGGCTGCCGTAAGAATTTCTTCCTGTCCAAGATCCGGTCCCACGTGGCTACTTGTTCCAAATACCAGAATTACATCATGGAAG
GTGTGAAGGCCACCATTAAGGATGCATCTCTTCAGCCAAGGAATGTTCCAAACCGTTACACCTTTCCTTGTCCTTACTGTCCTGAGAAGA
ACTTTGATCAGGAAGGACTTGTGGAACACTGCAAATTATTCCATAGCACGGATACCAAATCTGTGGTTTGTCCGATATGTGCCTCGATGC
CCTGGGGAGACCCCAACTACCGCAGCGCCAACTTCAGAGAGCACATCCAGCGCCGGCACCGGTTTTCTTATGACACTTTTGTGGATATCC
GACATGAAGCCAGTGACTTCCCATGTAGAGTGGCCAAGCTTCCTAAGAACAAAAACCGAAATAGGTACAGAGACGTCAGTCCCTTTGACC
ATAGTCGGATTAAACTACATCAAGAAGATAATGACTATATCAACGCTAGTTTGATAAAAATGGAAGAAGCCCAAAGGAGTTACATTCTTA
CCCAGGGCCCTTTGCCTAACACATGCGGTCACTTTTGGGAGATGGTGTGGGAGCAGAAAAGCAGGGGTGTCGTCATGCTCAACAGAGTGA
TGGAGAAAGGTTCGTTAAAATGCGCACAATACTGGCCACAAAAAGAAGAAAAAGAGATGATCTTTGAAGACACAAATTTGAAATTAACAT
TGATCTCTGAAGATATCAAGTCATATTATACAGTGCGACAGCTAGAATTGGAAAACCTTACAACCCAAGAAACTCGAGAGATCTTACATT
TCCACTATACCACATGGCCTGACTTTGGAGTCCCTGAATCACCAGCCTCATTCTTGAACTTTCTTTTCAAAGTCCGAGAGTCAGGGTCAC
TCAGCCCGGAGCACGGGCCCGTTGTGGTGCACTGCAGTGCAGGCATCGGCAGGTCTGGAACCTTCTGTCTGGCTGATACCTGCCTCTTGC
TGATGGACAAGAGGAAAGACCCTTCTTCCGTTGATATCAAGAAAGTGCTGTTAGAAATGAGGAAGTTTCGGATGGGGCTGATCCAGACAG
CCGACCAGCTGCGCTTCTCCTACCTGGCTGTGATCGAAGGTGCCAAATTCATCATGGGGGACTCTTCCGTGCAGGATCAGTGGAAGGAGC
TTTCCCACGAGGACCTGGAGCCCCCACCCGAGCATATCCCCCCACCTCCCCGGCCACCCAAACGAATCCTGGAGCCACACAATGGGAAAT
GCAGGGAGTTCTTCCCAAATCACCAGTGGGTGAAGGAAGAGACCCAGGAGGATAAAGACTGCCCCATCAAGGAAGAAAAAGGAAGCCCCT
TAAATGCCGCACCCTACGGCATCGAAAGCATGAGTCAAGACACTGAAGTTAGAAGTCGGGTCGTGGGGGGAAGTCTTCGAGGTGCCCAGG
CTGCCTCCCCAGCCAAAGGGGAGCCGTCACTGCCCGAGAAGGACGAGGACCATGCACTGAGTTACTGGAAGCCCTTCCTGGTCAACATGT
GCGTGGCTACGGTCCTCACGGCCGGCGCTTACCTCTGCTACAGGTTCCTGTTCAACAGCAACACATAGCCTGACCCTCCTCCACTCCACC
TCCACCCACTGTCCGCCTCTGCCCGCAGAGCCCACGCCCGACTAGCAGGCATGCCGCGGTAGGTAAGGGCCGCCGGACCGCGTAGAGAGC
CGGGCCCCGGACGGACGTTGGTTCTGCACTAAAACCCATCTTCCCCGGATGTGTGTCTCACCCCTCATCCTTTTACTTTTTGCCCCTTCC
ACTTTGAGTACCAAATCCACAAGCCATTTTTTGAGGAGAGTGAAAGAGAGTACCATGCTGGCGGCGCAGAGGGAAGGGGCCTACACCCGT
CTTGGGGCTCGCCCCACCCAGGGCTCCCTCCTGGAGCATCCCAGGCGGGCGGCACGCCAACAGCCCCCCCCTTGAATCTGCAGGGAGCAA
CTCTCCACTCCATATTTATTTAAACAATTTTTTCCCCAAAGGCATCCATAGTGCACTAGCATTTTCTTGAACCAATAATGTATTAAAATT
TTTTGATGTCAGCCTTGCATCAAGGGCTTTATCAAAAAGTACAATAATAAATCCTCAGGTAGTACTGGGAATGGAAGGCTTTGCCATGGG
CCTGCTGCGTCAGACCAGTACTGGGAAGGAGGACGGTTGTAAGCAGTTGTTATTTAGTGATATTGTGGGTAACGTGAGAAGATAGAACAA
TGCTATAATATATAATGAACACGTGGGTATTTAATAAGAAACATGATGTGAGATTACTTTGTCCCGCTTATTCTCCTCCCTGTTATCTGC
TAGATCTAGTTCTCAATCACTGCTCCCCCGTGTGTATTAGAATGCATGTAAGGTCTTCTTGTGTCCTGATGAAAAATATGTGCTTGAAAT
GAGAAACTTTGATCTCTGCTTACTAATGTGCCCCATGTCCAAGTCCAACCTGCCTGTGCATGACCTGATCATTACATGGCTGTGGTTCCT
AAGCCTGTTGCTGAAGTCATTGTCGCTCAGCAATAGGGTGCAGTTTTCCAGGAATAGGCATTTGCCTAATTCCTGGCATGACACTCTAGT
GACTTCCTGGTGAGGCCCAGCCTGTCCTGGTACAGCAGGGTCTTGCTGTAACTCAGACATTCCAAGGGTATGGGAAGCCATATTCACACC
TCACGCTCTGGACATGATTTAGGGAAGCAGGGACACCCCCCGCCCCCCACCTTTGGGATCAGCCTCCGCCATTCCAAGTCAACACTCTTC
TTGAGCAGACCGTGATTTGGAAGAGAGGCACCTGCTGGAAACCACACTTCTTGAAACAGCCTGGGTGACGGTCCTTTAGGCAGCCTGCCG
CCGTCTCTGTCCCGGTTCACCTTGCCGAGAGAGGCGCGTCTGCCCCACCCTCAAACCCTGTGGGGCCTGATGGTGCTCACGACTCTTCCT
GCAAAGGGAACTGAAGACCTCCACATTAAGTGGCTTTTTAACATGAAAAACACGGCAGCTGTAGCTCCCGAGCTACTCTCTTGCCAGCAT
TTTCACATTTTGCCTTTCTCGTGGTAGAAGCCAGTACAGAGAAATTCTGTGGTGGGAACATTCGAGGTGTCACCCTGCAGAGCTATGGTG
AGGTGTGGATAAGGCTTAGGTGCCAGGCTGTAAGCATTCTGAGCTGGGCTTGTTGTTTTTAAGTCCTGTATATGTATGTAGTAGTTTGGG
TGTGTATATATAGTAGCATTTCAAAATGGACGTACTGGTTTAACCTCCTATCCTTGGAGAGCAGCTGGCTCTCCACCTTGTTACACATTA
TGTTAGAGAGGTAGCGAGCTGCTCTGCTATATGCCTTAAGCCAATATTTACTCATCAGGTCATTATTTTTTACAATGGCCATGGAATAAA
CCATTTTTACAAAAATAAAAACAAAAAAAGCAAGGTGTTTTGGTATAATACCTTTTCAGGTGTGTGTGGATACGTGGCTGCATGACCGGG
TGGGTGGGGGGGAGTGTCTCAGGGTCTTCTGTGACCTCACAGAACTGTCAGACTGTACAGTTTTCCAACTTGCCATATTCATGATGGGTT


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FusionGenePPI for RNF114_PTPN1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
RNF114AK5, PARP11, UBE2U, UBE2D1, UBE2D2, UBE2D3, UBE2D4, UBE2E3, UBE2E2, UEVLD, UBE2DNL, UBE2E1, UBE2H, UBE2K, UBE2W, UBC, MAPK3, HSP90AA1, CPLX1, LAGE3, NUDCD2, DSTN, HSPB1, XAF1, CDKN1A, RNF114, TRIM52, RNF38, BMI1, TRIM55, TRAF6, TRAF4, TRAIP, EVI2A, RPSA, TNFAIP3, SUZ12, RNF2, MAP3K1, USO1, IDI2, AUP1, DTX3, EWSR1, SMURF1, PARP12, CD93, LTBR, PLP1, LACRT, RNF166, APC, MAVSPTPN1GSK3B, GRB2, IRS1, CAV1, EGFR, CRK, BCAR1, CTNNB1, STAT5A, STAT5B, NTRK1, NTRK2, NTRK3, LTK, TYK2, JAK2, INSR, IGF1R, GHR, STAM2, ILF3, SLC25A3, MCAT, MARCKSL1, LAMTOR3, HNRNPU, ZMPSTE24, STAT3, ATF2, CSNK2A1, SRC, ATP4A, ASS1, RFWD2, IL1B, ASGR2, HMOX2, SLC39A4, LYPD3, ENPP6, ZACN, PLTP, LYPD6, KRAS, AGR3, BCAS3, CASC3, CASZ1, CCL5, CDH13, DIRAS3, FAM84B, KLK7, MRC2, RHOBTB2, SNAI1, THRSP, VPS45, HERC2, TCTN2, TCTN3, EVC2, TMEM17, TMEM216, ATP6V1B2, ATP6V0A1, COL5A1, STOM, FLOT2, GALNT2, MSN, PHB, ABCD3, SMARCD2, ATP6V0D1, GOSR1, MVP, FLOT1, PHB2, LTN1, GOLIM4, BCOR, WRAP53, MREG, PCNP, KIDINS220, RNF213, ARHGAP39, PTRF, CDH1, ACTB, APLP2, CASC4, SNRPD2, TOMM70A, CTDNEP1, C5AR2, TMEM63A, C3AR1, GPR21, GHITM, SLCO6A1, TMPRSS3, AMTN, MRAP2, GPR114, KIAA1467, SLC39A12, APLNR, DUSP1, DCUN1D5, PISD, COX11, NDUFAF4, NARS, PTRH2, TBC1D15, NPPC, PFN2, ARL1, DHCR24, AIP, RAB5C, PGRMC1, SEC61A1, CDIPT, SLC27A4, ILVBL, DHCR7, TRIP13, ARF4, HEATR3, PCMT1, ARF1, CCDC47, CDK4, FLAD1, RMDN3, CLK2, LAT


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for RNF114_PTPN1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
TgenePTPN1P18031DB01133Tiludronic acidTyrosine-protein phosphatase non-receptor type 1small moleculeapproved|investigational|vet_approved

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RelatedDiseases for RNF114_PTPN1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneRNF114C0033860Psoriasis1CTD_human
TgenePTPN1C0019829Hodgkin Disease1CTD_human
TgenePTPN1C0021655Insulin Resistance1CTD_human
TgenePTPN1C0023893Liver Cirrhosis, Experimental1CTD_human
TgenePTPN1C0025063Mediastinal Neoplasms1CTD_human
TgenePTPN1C0028754Obesity1CTD_human
TgenePTPN1C0035372Rett Syndrome1CTD_human
TgenePTPN1C0036341Schizophrenia1PSYGENET
TgenePTPN1C0079731B-Cell Lymphomas1CTD_human