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Fusion gene ID: 31042 |
FusionGeneSummary for RFWD2_DDR2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: RFWD2_DDR2 | Fusion gene ID: 31042 | Hgene | Tgene | Gene symbol | RFWD2 | DDR2 | Gene ID | 4921 |
| Gene name | discoidin domain receptor tyrosine kinase 2 | ||
| Synonyms | MIG20a|NTRKR3|TKT|TYRO10 | ||
| Cytomap | 1q23.3 | ||
| Type of gene | protein-coding | ||
| Description | discoidin domain-containing receptor 2CD167 antigen-like family member Bcell migration-inducing protein 20discoidin domain receptor 2discoidin domain receptor family, member 2discoidin domain-containing receptor tyrosine kinase 2hydroxyaryl-protein | ||
| Modification date | 20180523 | ||
| UniProtAcc | Q16832 | ||
| Ensembl transtripts involved in fusion gene | ENST00000367669, ENST00000308769, | ENST00000367922, ENST00000367921, | |
| Fusion gene scores | * DoF score | 8 X 6 X 6=288 | 7 X 5 X 5=175 |
| # samples | 8 | 7 | |
| ** MAII score | log2(8/288*10)=-1.84799690655495 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(7/175*10)=-1.32192809488736 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: RFWD2 [Title/Abstract] AND DDR2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Oncogene involved fusion gene, in-frame and retained their domain. Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. Tumor suppressor gene involved fusion gene, retained protein feature but frameshift. DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain. Kinase involved fusion gene, inframe and retained kinase domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | DDR2 | GO:0018108 | peptidyl-tyrosine phosphorylation | 20004161 |
| Tgene | DDR2 | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway | 16186108 |
| Tgene | DDR2 | GO:0046777 | protein autophosphorylation | 16186108 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | SKCM | TCGA-BF-AAP4-01A | RFWD2 | chr1 | 175996708 | - | DDR2 | chr1 | 162722885 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000367669 | ENST00000367922 | RFWD2 | chr1 | 175996708 | - | DDR2 | chr1 | 162722885 | + |
| In-frame | ENST00000367669 | ENST00000367921 | RFWD2 | chr1 | 175996708 | - | DDR2 | chr1 | 162722885 | + |
| In-frame | ENST00000308769 | ENST00000367922 | RFWD2 | chr1 | 175996708 | - | DDR2 | chr1 | 162722885 | + |
| In-frame | ENST00000308769 | ENST00000367921 | RFWD2 | chr1 | 175996708 | - | DDR2 | chr1 | 162722885 | + |
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FusionProtFeatures for RFWD2_DDR2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| RFWD2 | DDR2 |
| Lectin that binds to various sugars: galactose > mannose= fucose > N-acetylglucosamine > N-acetylgalactosamine(PubMed:10224141). Acts as a chemoattractant, probably involved inthe regulation of cell migration (PubMed:28301481).{ECO:0000269|PubMed:10224141, ECO:0000269|PubMed:28301481}. | Tyrosine kinase that functions as cell surface receptorfor fibrillar collagen and regulates cell differentiation,remodeling of the extracellular matrix, cell migration and cellproliferation. Required for normal bone development. Regulatesosteoblast differentiation and chondrocyte maturation via asignaling pathway that involves MAP kinases and leads to theactivation of the transcription factor RUNX2. Regulates remodelingof the extracellular matrix by up-regulation of the collagenasesMMP1, MMP2 and MMP13, and thereby facilitates cell migration andtumor cell invasion. Promotes fibroblast migration andproliferation, and thereby contributes to cutaneous wound healing.{ECO:0000269|PubMed:16186104, ECO:0000269|PubMed:16186108,ECO:0000269|PubMed:17665456, ECO:0000269|PubMed:18201965,ECO:0000269|PubMed:20004161, ECO:0000269|PubMed:20564243,ECO:0000269|PubMed:20734453, ECO:0000269|PubMed:9659899}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | RFWD2 | chr1:175996708 | chr1:162722885 | ENST00000308769 | - | 14 | 19 | 233_301 | 552 | 708 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | RFWD2 | chr1:175996708 | chr1:162722885 | ENST00000367669 | - | 15 | 20 | 233_301 | 576 | 732 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | RFWD2 | chr1:175996708 | chr1:162722885 | ENST00000308769 | - | 14 | 19 | 2_110 | 552 | 708 | Compositional bias | Note=Ser-rich |
| Hgene | RFWD2 | chr1:175996708 | chr1:162722885 | ENST00000367669 | - | 15 | 20 | 2_110 | 576 | 732 | Compositional bias | Note=Ser-rich |
| Hgene | RFWD2 | chr1:175996708 | chr1:162722885 | ENST00000308769 | - | 14 | 19 | 109_113 | 552 | 708 | Motif | Note=Nuclear localization signal 1 |
| Hgene | RFWD2 | chr1:175996708 | chr1:162722885 | ENST00000308769 | - | 14 | 19 | 195_206 | 552 | 708 | Motif | Note=Nuclear localization signal 2 |
| Hgene | RFWD2 | chr1:175996708 | chr1:162722885 | ENST00000308769 | - | 14 | 19 | 235_245 | 552 | 708 | Motif | Nuclear export signal |
| Hgene | RFWD2 | chr1:175996708 | chr1:162722885 | ENST00000367669 | - | 15 | 20 | 109_113 | 576 | 732 | Motif | Note=Nuclear localization signal 1 |
| Hgene | RFWD2 | chr1:175996708 | chr1:162722885 | ENST00000367669 | - | 15 | 20 | 195_206 | 576 | 732 | Motif | Note=Nuclear localization signal 2 |
| Hgene | RFWD2 | chr1:175996708 | chr1:162722885 | ENST00000367669 | - | 15 | 20 | 235_245 | 576 | 732 | Motif | Nuclear export signal |
| Hgene | RFWD2 | chr1:175996708 | chr1:162722885 | ENST00000308769 | - | 14 | 19 | 419_458 | 552 | 708 | Repeat | Note=WD 1 |
| Hgene | RFWD2 | chr1:175996708 | chr1:162722885 | ENST00000308769 | - | 14 | 19 | 468_508 | 552 | 708 | Repeat | Note=WD 2 |
| Hgene | RFWD2 | chr1:175996708 | chr1:162722885 | ENST00000308769 | - | 14 | 19 | 511_551 | 552 | 708 | Repeat | Note=WD 3 |
| Hgene | RFWD2 | chr1:175996708 | chr1:162722885 | ENST00000367669 | - | 15 | 20 | 419_458 | 576 | 732 | Repeat | Note=WD 1 |
| Hgene | RFWD2 | chr1:175996708 | chr1:162722885 | ENST00000367669 | - | 15 | 20 | 468_508 | 576 | 732 | Repeat | Note=WD 2 |
| Hgene | RFWD2 | chr1:175996708 | chr1:162722885 | ENST00000367669 | - | 15 | 20 | 511_551 | 576 | 732 | Repeat | Note=WD 3 |
| Hgene | RFWD2 | chr1:175996708 | chr1:162722885 | ENST00000308769 | - | 14 | 19 | 136_174 | 552 | 708 | Zinc finger | RING-type |
| Hgene | RFWD2 | chr1:175996708 | chr1:162722885 | ENST00000367669 | - | 15 | 20 | 136_174 | 576 | 732 | Zinc finger | RING-type |
| Tgene | >DDR2 | chr1:175996708 | chr1:162722885 | ENST00000367921 | + | 2 | 18 | 563_849 | 27 | 856 | Domain | Protein kinase |
| Tgene | >DDR2 | chr1:175996708 | chr1:162722885 | ENST00000367922 | + | 3 | 19 | 563_849 | 27 | 856 | Domain | Protein kinase |
| Tgene | >DDR2 | chr1:175996708 | chr1:162722885 | ENST00000367921 | + | 2 | 18 | 569_577 | 27 | 856 | Nucleotide binding | ATP |
| Tgene | >DDR2 | chr1:175996708 | chr1:162722885 | ENST00000367922 | + | 3 | 19 | 569_577 | 27 | 856 | Nucleotide binding | ATP |
| Tgene | >DDR2 | chr1:175996708 | chr1:162722885 | ENST00000367921 | + | 2 | 18 | 422_855 | 27 | 856 | Topological domain | Cytoplasmic |
| Tgene | >DDR2 | chr1:175996708 | chr1:162722885 | ENST00000367922 | + | 3 | 19 | 422_855 | 27 | 856 | Topological domain | Cytoplasmic |
| Tgene | >DDR2 | chr1:175996708 | chr1:162722885 | ENST00000367921 | + | 2 | 18 | 400_421 | 27 | 856 | Transmembrane | Helical |
| Tgene | >DDR2 | chr1:175996708 | chr1:162722885 | ENST00000367922 | + | 3 | 19 | 400_421 | 27 | 856 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >RFWD2 | chr1:175996708 | chr1:162722885 | ENST00000308769 | - | 14 | 19 | 553_593 | 552 | 708 | Repeat | Note=WD 4 |
| Hgene | >RFWD2 | chr1:175996708 | chr1:162722885 | ENST00000308769 | - | 14 | 19 | 597_635 | 552 | 708 | Repeat | Note=WD 5 |
| Hgene | >RFWD2 | chr1:175996708 | chr1:162722885 | ENST00000308769 | - | 14 | 19 | 638_677 | 552 | 708 | Repeat | Note=WD 6 |
| Hgene | >RFWD2 | chr1:175996708 | chr1:162722885 | ENST00000308769 | - | 14 | 19 | 691_729 | 552 | 708 | Repeat | Note=WD 7 |
| Hgene | >RFWD2 | chr1:175996708 | chr1:162722885 | ENST00000367669 | - | 15 | 20 | 553_593 | 576 | 732 | Repeat | Note=WD 4 |
| Hgene | >RFWD2 | chr1:175996708 | chr1:162722885 | ENST00000367669 | - | 15 | 20 | 597_635 | 576 | 732 | Repeat | Note=WD 5 |
| Hgene | >RFWD2 | chr1:175996708 | chr1:162722885 | ENST00000367669 | - | 15 | 20 | 638_677 | 576 | 732 | Repeat | Note=WD 6 |
| Hgene | >RFWD2 | chr1:175996708 | chr1:162722885 | ENST00000367669 | - | 15 | 20 | 691_729 | 576 | 732 | Repeat | Note=WD 7 |
| Tgene | DDR2 | chr1:175996708 | chr1:162722885 | ENST00000367921 | + | 2 | 18 | 22_399 | 27 | 856 | Topological domain | Extracellular |
| Tgene | DDR2 | chr1:175996708 | chr1:162722885 | ENST00000367922 | + | 3 | 19 | 22_399 | 27 | 856 | Topological domain | Extracellular |
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FusionGeneSequence for RFWD2_DDR2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_RFWD2_ENST00000367669_chr1_175996708_-_DDR2_ENST00000367922_chr1_162722885_+_1405aa MSGSRQAGSGSAGTSPGSSAASSVTSASSSLSSSPSPPSVAVSAAALVSGGVAQAAGSGGLGGPVRPVLVAPAVSGSGGGAVSTGLSRHS CAARPSAGVGGSSSSLGSGSRKRPLLAPLCNGLINSYEDKSNDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKCNYVVDNI DHLYPNFLVNELILKQKQRFEEKRFKLDHSVSSTNGHRWQIFQDWLGTDQDNLDLANVNLMLELLVQKKKQLEAESHAAQLQILMEFLKV ARRNKREQLEQIQKELSVLEEDIKRVEEMSGLYSPVSEDSTVPQFEAPSPSHSSIIDSTEYSQPPGFSGSSQTKKQPWYNSTLASRRKRL TAHFEDLEQCYFSTRMSRISDDSRTASQLDEFQECLSKFTRYNSVRPLATLSYASDLYNGSSIVSSIEFDRDCDYFAIAGVTKKIKVYEY DTVIQDAVDIHYPENEMTCNSKISCISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKL WSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCAAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPD DLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTD HSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRN ESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYH FADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEM TVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQG VTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARND FLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDL ATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENT >In-frame_RFWD2_ENST00000367669_chr1_175996708_-_DDR2_ENST00000367921_chr1_162722885_+_1405aa MSGSRQAGSGSAGTSPGSSAASSVTSASSSLSSSPSPPSVAVSAAALVSGGVAQAAGSGGLGGPVRPVLVAPAVSGSGGGAVSTGLSRHS CAARPSAGVGGSSSSLGSGSRKRPLLAPLCNGLINSYEDKSNDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKCNYVVDNI DHLYPNFLVNELILKQKQRFEEKRFKLDHSVSSTNGHRWQIFQDWLGTDQDNLDLANVNLMLELLVQKKKQLEAESHAAQLQILMEFLKV ARRNKREQLEQIQKELSVLEEDIKRVEEMSGLYSPVSEDSTVPQFEAPSPSHSSIIDSTEYSQPPGFSGSSQTKKQPWYNSTLASRRKRL TAHFEDLEQCYFSTRMSRISDDSRTASQLDEFQECLSKFTRYNSVRPLATLSYASDLYNGSSIVSSIEFDRDCDYFAIAGVTKKIKVYEY DTVIQDAVDIHYPENEMTCNSKISCISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKL WSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCAAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPD DLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTD HSMNVCMRVELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRN ESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYH FADTWMMFSEITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEM TVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQG VTGGNTYSVPAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARND FLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDL ATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENT >In-frame_RFWD2_ENST00000308769_chr1_175996708_-_DDR2_ENST00000367922_chr1_162722885_+_1381aa MSGSRQAGSGSAGTSPGSSAASSVTSASSSLSSSPSPPSVAVSAAALVSGGVAQAAGSGGLGGPVRPVLVAPAVSGSGGGAVSTGLSRHS CAARPSAGVGGSSSSLGSGSRKRPLLAPLCNGLINSYEDKSNDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKCNYVVDNI DHLYPNFLVNELILKQKQRFEEKRFKLDHSNGHRWQIFQDWLGTDQDNLDLANVNLMLELLVQKKKQLEAESHAAQLQILMEFLKVARRN KREEMSGLYSPVSEDSTVPQFEAPSPSHSSIIDSTEYSQPPGFSGSSQTKKQPWYNSTLASRRKRLTAHFEDLEQCYFSTRMSRISDDSR TASQLDEFQECLSKFTRYNSVRPLATLSYASDLYNGSSIVSSIEFDRDCDYFAIAGVTKKIKVYEYDTVIQDAVDIHYPENEMTCNSKIS CISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKLWSTNLDNSVASIEAKANVCCVKFS PSSRYHLAFGCAAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGR HAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYN APAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMK VHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSE ALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQ GSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAV EEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCI TDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNL YSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVY >In-frame_RFWD2_ENST00000308769_chr1_175996708_-_DDR2_ENST00000367921_chr1_162722885_+_1381aa MSGSRQAGSGSAGTSPGSSAASSVTSASSSLSSSPSPPSVAVSAAALVSGGVAQAAGSGGLGGPVRPVLVAPAVSGSGGGAVSTGLSRHS CAARPSAGVGGSSSSLGSGSRKRPLLAPLCNGLINSYEDKSNDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKCNYVVDNI DHLYPNFLVNELILKQKQRFEEKRFKLDHSNGHRWQIFQDWLGTDQDNLDLANVNLMLELLVQKKKQLEAESHAAQLQILMEFLKVARRN KREEMSGLYSPVSEDSTVPQFEAPSPSHSSIIDSTEYSQPPGFSGSSQTKKQPWYNSTLASRRKRLTAHFEDLEQCYFSTRMSRISDDSR TASQLDEFQECLSKFTRYNSVRPLATLSYASDLYNGSSIVSSIEFDRDCDYFAIAGVTKKIKVYEYDTVIQDAVDIHYPENEMTCNSKIS CISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEHEKRCWSVDFNLMDPKLLASGSDDAKVKLWSTNLDNSVASIEAKANVCCVKFS PSSRYHLAFGCAAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGR HAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGCVWLDGLVSYN APAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLDDFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMK VHCNNMFAKGVKIFKEVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFSEITFQSDAAMYNNSE ALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIILWRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQ GSNSTYDRIFPLRPDYQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSVPAVTMDLLSGKDVAV EEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSANQPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCI TDDPLCMITEYMENGDLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNL YSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWETFTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVY |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_RFWD2_ENST00000367669_chr1_175996708_-_DDR2_ENST00000367922_chr1_162722885_+_4215nt ATGTCTGGTAGCCGCCAGGCCGGGTCGGGCTCCGCTGGGACAAGCCCCGGGTCCTCGGCGGCCTCCTCGGTGACTTCCGCCTCCTCGTCT TTATCCTCTTCCCCGTCGCCGCCTTCCGTGGCGGTTTCGGCGGCAGCGCTGGTGTCCGGCGGGGTGGCCCAGGCCGCCGGCTCGGGCGGC CTCGGGGGCCCGGTGCGGCCTGTGTTGGTGGCGCCCGCCGTATCGGGTAGCGGCGGCGGGGCGGTGTCCACGGGCCTGTCCCGGCACAGC TGCGCGGCCAGGCCCAGCGCCGGCGTAGGAGGCAGCAGCTCCAGCCTAGGCAGCGGCAGCAGGAAGCGACCTCTCCTCGCCCCCCTCTGC AACGGGCTCATCAACTCCTACGAGGACAAAAGCAACGACTTCGTATGCCCCATCTGCTTTGATATGATTGAAGAAGCATACATGACAAAA TGTGGCCACAGCTTTTGCTACAAGTGTATTCATCAGAGTTTGGAGGACAATAATAGATGTCCCAAGTGTAACTATGTTGTGGACAATATT GACCATCTGTATCCTAATTTCTTGGTGAATGAACTCATTCTTAAACAGAAGCAAAGATTTGAGGAAAAGAGGTTCAAATTGGACCACTCA GTGAGTAGCACCAATGGCCACAGGTGGCAGATATTTCAAGATTGGTTGGGAACTGACCAAGATAACCTTGATTTGGCCAATGTCAATCTT ATGTTGGAGTTACTAGTGCAGAAGAAGAAACAACTGGAAGCAGAATCACATGCAGCCCAACTACAGATTCTTATGGAATTCCTCAAGGTT GCAAGAAGAAATAAGAGAGAGCAACTGGAACAGATCCAGAAGGAGCTAAGTGTTTTGGAAGAGGATATTAAGAGAGTGGAAGAAATGAGT GGCTTATACTCTCCTGTCAGTGAGGATAGCACAGTGCCTCAATTTGAAGCTCCTTCTCCATCACACAGTAGTATTATTGATTCCACAGAA TACAGCCAACCTCCAGGTTTCAGTGGCAGTTCTCAGACAAAGAAACAGCCTTGGTATAATAGCACGTTAGCATCAAGACGAAAACGACTT ACTGCTCATTTTGAAGACTTGGAGCAGTGTTACTTTTCTACAAGGATGTCTCGTATCTCAGATGACAGTCGAACTGCAAGCCAGTTGGAT GAATTTCAGGAATGCTTGTCCAAGTTTACTCGATATAATTCAGTACGACCTTTAGCCACATTGTCATATGCTAGTGATCTCTATAATGGT TCCAGTATAGTCTCTAGTATTGAATTTGACCGGGATTGTGACTATTTTGCGATTGCTGGAGTTACAAAGAAGATTAAAGTCTATGAATAT GACACTGTCATCCAGGATGCAGTGGATATTCATTACCCTGAGAATGAAATGACCTGCAATTCGAAAATCAGCTGTATCAGTTGGAGTAGT TACCATAAGAACCTGTTAGCTAGCAGTGATTATGAAGGCACTGTTATTTTATGGGATGGATTCACAGGACAGAGGTCAAAGGTCTATCAG GAGCATGAGAAGAGGTGTTGGAGTGTTGACTTTAATTTGATGGATCCTAAACTCTTGGCTTCAGGTTCTGATGATGCAAAAGTGAAGCTG TGGTCTACCAATCTAGACAACTCAGTGGCAAGCATTGAGGCAAAGGCTAATGTGTGCTGTGTTAAATTCAGCCCCTCTTCCAGATACCAT TTGGCTTTCGGCTGTGCAGCTATATGCCGCTATCCTCTGGGCATGTCAGGAGGCCAGATTCCAGATGAGGACATCACAGCTTCCAGTCAG TGGTCAGAGTCCACAGCTGCCAAATATGGAAGGCTGGACTCAGAAGAAGGGGATGGAGCCTGGTGCCCTGAGATTCCAGTGGAACCTGAT GACCTGAAGGAGTTTCTGCAGATTGACTTGCACACCCTCCATTTTATCACTCTGGTGGGGACCCAGGGGCGCCATGCAGGAGGTCATGGC ATCGAGTTTGCCCCCATGTACAAGATCAATTACAGTCGGGATGGCACTCGCTGGATCTCTTGGCGGAACCGTCATGGGAAACAGGTGCTG GATGGAAATAGTAACCCCTATGACATTTTCCTAAAGGACTTGGAGCCGCCCATTGTAGCCAGATTTGTCCGGTTCATTCCAGTCACCGAC CACTCCATGAATGTGTGTATGAGAGTGGAGCTTTACGGCTGTGTCTGGCTAGATGGCTTGGTGTCTTACAATGCTCCAGCTGGGCAGCAG TTTGTACTCCCTGGAGGTTCCATCATTTATCTGAATGATTCTGTCTATGATGGAGCTGTTGGATACAGCATGACAGAAGGGCTAGGCCAA TTGACCGATGGTGTGTCTGGCCTGGACGATTTCACCCAGACCCATGAATACCACGTGTGGCCCGGCTATGACTATGTGGGCTGGCGGAAC GAGAGTGCCACCAATGGCTACATTGAGATCATGTTTGAATTTGACCGCATCAGGAATTTCACTACCATGAAGGTCCACTGCAACAACATG TTTGCTAAAGGTGTGAAGATCTTTAAGGAGGTACAGTGCTACTTCCGCTCTGAAGCCAGTGAGTGGGAACCTAATGCCATTTCCTTCCCC CTTGTCCTGGATGACGTCAACCCCAGTGCTCGGTTTGTCACGGTGCCTCTCCACCACCGAATGGCCAGTGCCATCAAGTGTCAATACCAT TTTGCAGATACCTGGATGATGTTCAGTGAGATCACCTTCCAATCAGATGCTGCAATGTACAACAACTCTGAAGCCCTGCCCACCTCTCCT ATGGCACCCACAACCTATGATCCAATGCTTAAAGTTGATGACAGCAACACTCGGATCCTGATTGGCTGCTTGGTGGCCATCATCTTTATC CTCCTGGCCATCATTGTCATCATCCTCTGGAGGCAGTTCTGGCAGAAAATGCTGGAGAAGGCTTCTCGGAGGATGCTGGATGATGAAATG ACAGTCAGCCTTTCCCTGCCAAGTGATTCTAGCATGTTCAACAATAACCGCTCCTCATCACCTAGTGAACAAGGGTCCAACTCGACTTAC GATCGCATCTTTCCCCTTCGCCCTGACTACCAGGAGCCATCCAGGCTGATACGAAAACTCCCAGAATTTGCTCCAGGGGAGGAGGAGTCA GGCTGCAGCGGTGTTGTGAAGCCAGTCCAGCCCAGTGGCCCTGAGGGGGTGCCCCACTATGCAGAGGCTGACATAGTGAACCTCCAAGGA GTGACAGGAGGCAACACATACTCAGTGCCTGCCGTCACCATGGACCTGCTCTCAGGAAAAGATGTGGCTGTGGAGGAGTTCCCCAGGAAA CTCCTAACTTTCAAAGAGAAGCTGGGAGAAGGACAGTTTGGGGAGGTTCATCTCTGTGAAGTGGAGGGAATGGAAAAATTCAAAGACAAA GATTTTGCCCTAGATGTCAGTGCCAACCAGCCTGTCCTGGTGGCTGTGAAAATGCTCCGAGCAGATGCCAACAAGAATGCCAGGAATGAT TTTCTTAAGGAGATAAAGATCATGTCTCGGCTCAAGGACCCAAACATCATCCATCTATTAGCTGTGTGTATCACTGATGACCCTCTCTGT ATGATCACTGAATACATGGAGAATGGAGATCTCAATCAGTTTCTTTCCCGCCACGAGCCCCCTAATTCTTCCTCCAGCGATGTACGCACT GTCAGTTACACCAATCTGAAGTTTATGGCTACCCAAATTGCCTCTGGCATGAAGTACCTTTCCTCTCTTAATTTTGTTCACCGAGATCTG GCCACACGAAACTGTTTAGTGGGTAAGAACTACACAATCAAGATAGCTGACTTTGGAATGAGCAGGAACCTGTACAGTGGTGACTATTAC CGGATCCAGGGCCGGGCAGTGCTCCCTATCCGCTGGATGTCTTGGGAGAGTATCTTGCTGGGCAAGTTCACTACAGCAAGTGATGTGTGG GCCTTTGGGGTTACTTTGTGGGAGACTTTCACCTTTTGTCAAGAACAGCCCTATTCCCAGCTGTCAGATGAACAGGTTATTGAGAATACT GGAGAGTTCTTCCGAGACCAAGGGAGGCAGACTTACCTCCCTCAACCAGCCATTTGTCCTGACTCTGTGTATAAGCTGATGCTCAGCTGC >In-frame_RFWD2_ENST00000367669_chr1_175996708_-_DDR2_ENST00000367921_chr1_162722885_+_4215nt ATGTCTGGTAGCCGCCAGGCCGGGTCGGGCTCCGCTGGGACAAGCCCCGGGTCCTCGGCGGCCTCCTCGGTGACTTCCGCCTCCTCGTCT TTATCCTCTTCCCCGTCGCCGCCTTCCGTGGCGGTTTCGGCGGCAGCGCTGGTGTCCGGCGGGGTGGCCCAGGCCGCCGGCTCGGGCGGC CTCGGGGGCCCGGTGCGGCCTGTGTTGGTGGCGCCCGCCGTATCGGGTAGCGGCGGCGGGGCGGTGTCCACGGGCCTGTCCCGGCACAGC TGCGCGGCCAGGCCCAGCGCCGGCGTAGGAGGCAGCAGCTCCAGCCTAGGCAGCGGCAGCAGGAAGCGACCTCTCCTCGCCCCCCTCTGC AACGGGCTCATCAACTCCTACGAGGACAAAAGCAACGACTTCGTATGCCCCATCTGCTTTGATATGATTGAAGAAGCATACATGACAAAA TGTGGCCACAGCTTTTGCTACAAGTGTATTCATCAGAGTTTGGAGGACAATAATAGATGTCCCAAGTGTAACTATGTTGTGGACAATATT GACCATCTGTATCCTAATTTCTTGGTGAATGAACTCATTCTTAAACAGAAGCAAAGATTTGAGGAAAAGAGGTTCAAATTGGACCACTCA GTGAGTAGCACCAATGGCCACAGGTGGCAGATATTTCAAGATTGGTTGGGAACTGACCAAGATAACCTTGATTTGGCCAATGTCAATCTT ATGTTGGAGTTACTAGTGCAGAAGAAGAAACAACTGGAAGCAGAATCACATGCAGCCCAACTACAGATTCTTATGGAATTCCTCAAGGTT GCAAGAAGAAATAAGAGAGAGCAACTGGAACAGATCCAGAAGGAGCTAAGTGTTTTGGAAGAGGATATTAAGAGAGTGGAAGAAATGAGT GGCTTATACTCTCCTGTCAGTGAGGATAGCACAGTGCCTCAATTTGAAGCTCCTTCTCCATCACACAGTAGTATTATTGATTCCACAGAA TACAGCCAACCTCCAGGTTTCAGTGGCAGTTCTCAGACAAAGAAACAGCCTTGGTATAATAGCACGTTAGCATCAAGACGAAAACGACTT ACTGCTCATTTTGAAGACTTGGAGCAGTGTTACTTTTCTACAAGGATGTCTCGTATCTCAGATGACAGTCGAACTGCAAGCCAGTTGGAT GAATTTCAGGAATGCTTGTCCAAGTTTACTCGATATAATTCAGTACGACCTTTAGCCACATTGTCATATGCTAGTGATCTCTATAATGGT TCCAGTATAGTCTCTAGTATTGAATTTGACCGGGATTGTGACTATTTTGCGATTGCTGGAGTTACAAAGAAGATTAAAGTCTATGAATAT GACACTGTCATCCAGGATGCAGTGGATATTCATTACCCTGAGAATGAAATGACCTGCAATTCGAAAATCAGCTGTATCAGTTGGAGTAGT TACCATAAGAACCTGTTAGCTAGCAGTGATTATGAAGGCACTGTTATTTTATGGGATGGATTCACAGGACAGAGGTCAAAGGTCTATCAG GAGCATGAGAAGAGGTGTTGGAGTGTTGACTTTAATTTGATGGATCCTAAACTCTTGGCTTCAGGTTCTGATGATGCAAAAGTGAAGCTG TGGTCTACCAATCTAGACAACTCAGTGGCAAGCATTGAGGCAAAGGCTAATGTGTGCTGTGTTAAATTCAGCCCCTCTTCCAGATACCAT TTGGCTTTCGGCTGTGCAGCTATATGCCGCTATCCTCTGGGCATGTCAGGAGGCCAGATTCCAGATGAGGACATCACAGCTTCCAGTCAG TGGTCAGAGTCCACAGCTGCCAAATATGGAAGGCTGGACTCAGAAGAAGGGGATGGAGCCTGGTGCCCTGAGATTCCAGTGGAACCTGAT GACCTGAAGGAGTTTCTGCAGATTGACTTGCACACCCTCCATTTTATCACTCTGGTGGGGACCCAGGGGCGCCATGCAGGAGGTCATGGC ATCGAGTTTGCCCCCATGTACAAGATCAATTACAGTCGGGATGGCACTCGCTGGATCTCTTGGCGGAACCGTCATGGGAAACAGGTGCTG GATGGAAATAGTAACCCCTATGACATTTTCCTAAAGGACTTGGAGCCGCCCATTGTAGCCAGATTTGTCCGGTTCATTCCAGTCACCGAC CACTCCATGAATGTGTGTATGAGAGTGGAGCTTTACGGCTGTGTCTGGCTAGATGGCTTGGTGTCTTACAATGCTCCAGCTGGGCAGCAG TTTGTACTCCCTGGAGGTTCCATCATTTATCTGAATGATTCTGTCTATGATGGAGCTGTTGGATACAGCATGACAGAAGGGCTAGGCCAA TTGACCGATGGTGTGTCTGGCCTGGACGATTTCACCCAGACCCATGAATACCACGTGTGGCCCGGCTATGACTATGTGGGCTGGCGGAAC GAGAGTGCCACCAATGGCTACATTGAGATCATGTTTGAATTTGACCGCATCAGGAATTTCACTACCATGAAGGTCCACTGCAACAACATG TTTGCTAAAGGTGTGAAGATCTTTAAGGAGGTACAGTGCTACTTCCGCTCTGAAGCCAGTGAGTGGGAACCTAATGCCATTTCCTTCCCC CTTGTCCTGGATGACGTCAACCCCAGTGCTCGGTTTGTCACGGTGCCTCTCCACCACCGAATGGCCAGTGCCATCAAGTGTCAATACCAT TTTGCAGATACCTGGATGATGTTCAGTGAGATCACCTTCCAATCAGATGCTGCAATGTACAACAACTCTGAAGCCCTGCCCACCTCTCCT ATGGCACCCACAACCTATGATCCAATGCTTAAAGTTGATGACAGCAACACTCGGATCCTGATTGGCTGCTTGGTGGCCATCATCTTTATC CTCCTGGCCATCATTGTCATCATCCTCTGGAGGCAGTTCTGGCAGAAAATGCTGGAGAAGGCTTCTCGGAGGATGCTGGATGATGAAATG ACAGTCAGCCTTTCCCTGCCAAGTGATTCTAGCATGTTCAACAATAACCGCTCCTCATCACCTAGTGAACAAGGGTCCAACTCGACTTAC GATCGCATCTTTCCCCTTCGCCCTGACTACCAGGAGCCATCCAGGCTGATACGAAAACTCCCAGAATTTGCTCCAGGGGAGGAGGAGTCA GGCTGCAGCGGTGTTGTGAAGCCAGTCCAGCCCAGTGGCCCTGAGGGGGTGCCCCACTATGCAGAGGCTGACATAGTGAACCTCCAAGGA GTGACAGGAGGCAACACATACTCAGTGCCTGCCGTCACCATGGACCTGCTCTCAGGAAAAGATGTGGCTGTGGAGGAGTTCCCCAGGAAA CTCCTAACTTTCAAAGAGAAGCTGGGAGAAGGACAGTTTGGGGAGGTTCATCTCTGTGAAGTGGAGGGAATGGAAAAATTCAAAGACAAA GATTTTGCCCTAGATGTCAGTGCCAACCAGCCTGTCCTGGTGGCTGTGAAAATGCTCCGAGCAGATGCCAACAAGAATGCCAGGAATGAT TTTCTTAAGGAGATAAAGATCATGTCTCGGCTCAAGGACCCAAACATCATCCATCTATTAGCTGTGTGTATCACTGATGACCCTCTCTGT ATGATCACTGAATACATGGAGAATGGAGATCTCAATCAGTTTCTTTCCCGCCACGAGCCCCCTAATTCTTCCTCCAGCGATGTACGCACT GTCAGTTACACCAATCTGAAGTTTATGGCTACCCAAATTGCCTCTGGCATGAAGTACCTTTCCTCTCTTAATTTTGTTCACCGAGATCTG GCCACACGAAACTGTTTAGTGGGTAAGAACTACACAATCAAGATAGCTGACTTTGGAATGAGCAGGAACCTGTACAGTGGTGACTATTAC CGGATCCAGGGCCGGGCAGTGCTCCCTATCCGCTGGATGTCTTGGGAGAGTATCTTGCTGGGCAAGTTCACTACAGCAAGTGATGTGTGG GCCTTTGGGGTTACTTTGTGGGAGACTTTCACCTTTTGTCAAGAACAGCCCTATTCCCAGCTGTCAGATGAACAGGTTATTGAGAATACT GGAGAGTTCTTCCGAGACCAAGGGAGGCAGACTTACCTCCCTCAACCAGCCATTTGTCCTGACTCTGTGTATAAGCTGATGCTCAGCTGC >In-frame_RFWD2_ENST00000308769_chr1_175996708_-_DDR2_ENST00000367922_chr1_162722885_+_4143nt ATGTCTGGTAGCCGCCAGGCCGGGTCGGGCTCCGCTGGGACAAGCCCCGGGTCCTCGGCGGCCTCCTCGGTGACTTCCGCCTCCTCGTCT TTATCCTCTTCCCCGTCGCCGCCTTCCGTGGCGGTTTCGGCGGCAGCGCTGGTGTCCGGCGGGGTGGCCCAGGCCGCCGGCTCGGGCGGC CTCGGGGGCCCGGTGCGGCCTGTGTTGGTGGCGCCCGCCGTATCGGGTAGCGGCGGCGGGGCGGTGTCCACGGGCCTGTCCCGGCACAGC TGCGCGGCCAGGCCCAGCGCCGGCGTAGGAGGCAGCAGCTCCAGCCTAGGCAGCGGCAGCAGGAAGCGACCTCTCCTCGCCCCCCTCTGC AACGGGCTCATCAACTCCTACGAGGACAAAAGCAACGACTTCGTATGCCCCATCTGCTTTGATATGATTGAAGAAGCATACATGACAAAA TGTGGCCACAGCTTTTGCTACAAGTGTATTCATCAGAGTTTGGAGGACAATAATAGATGTCCCAAGTGTAACTATGTTGTGGACAATATT GACCATCTGTATCCTAATTTCTTGGTGAATGAACTCATTCTTAAACAGAAGCAAAGATTTGAGGAAAAGAGGTTCAAATTGGACCACTCA AATGGCCACAGGTGGCAGATATTTCAAGATTGGTTGGGAACTGACCAAGATAACCTTGATTTGGCCAATGTCAATCTTATGTTGGAGTTA CTAGTGCAGAAGAAGAAACAACTGGAAGCAGAATCACATGCAGCCCAACTACAGATTCTTATGGAATTCCTCAAGGTTGCAAGAAGAAAT AAGAGAGAGGAAATGAGTGGCTTATACTCTCCTGTCAGTGAGGATAGCACAGTGCCTCAATTTGAAGCTCCTTCTCCATCACACAGTAGT ATTATTGATTCCACAGAATACAGCCAACCTCCAGGTTTCAGTGGCAGTTCTCAGACAAAGAAACAGCCTTGGTATAATAGCACGTTAGCA TCAAGACGAAAACGACTTACTGCTCATTTTGAAGACTTGGAGCAGTGTTACTTTTCTACAAGGATGTCTCGTATCTCAGATGACAGTCGA ACTGCAAGCCAGTTGGATGAATTTCAGGAATGCTTGTCCAAGTTTACTCGATATAATTCAGTACGACCTTTAGCCACATTGTCATATGCT AGTGATCTCTATAATGGTTCCAGTATAGTCTCTAGTATTGAATTTGACCGGGATTGTGACTATTTTGCGATTGCTGGAGTTACAAAGAAG ATTAAAGTCTATGAATATGACACTGTCATCCAGGATGCAGTGGATATTCATTACCCTGAGAATGAAATGACCTGCAATTCGAAAATCAGC TGTATCAGTTGGAGTAGTTACCATAAGAACCTGTTAGCTAGCAGTGATTATGAAGGCACTGTTATTTTATGGGATGGATTCACAGGACAG AGGTCAAAGGTCTATCAGGAGCATGAGAAGAGGTGTTGGAGTGTTGACTTTAATTTGATGGATCCTAAACTCTTGGCTTCAGGTTCTGAT GATGCAAAAGTGAAGCTGTGGTCTACCAATCTAGACAACTCAGTGGCAAGCATTGAGGCAAAGGCTAATGTGTGCTGTGTTAAATTCAGC CCCTCTTCCAGATACCATTTGGCTTTCGGCTGTGCAGCTATATGCCGCTATCCTCTGGGCATGTCAGGAGGCCAGATTCCAGATGAGGAC ATCACAGCTTCCAGTCAGTGGTCAGAGTCCACAGCTGCCAAATATGGAAGGCTGGACTCAGAAGAAGGGGATGGAGCCTGGTGCCCTGAG ATTCCAGTGGAACCTGATGACCTGAAGGAGTTTCTGCAGATTGACTTGCACACCCTCCATTTTATCACTCTGGTGGGGACCCAGGGGCGC CATGCAGGAGGTCATGGCATCGAGTTTGCCCCCATGTACAAGATCAATTACAGTCGGGATGGCACTCGCTGGATCTCTTGGCGGAACCGT CATGGGAAACAGGTGCTGGATGGAAATAGTAACCCCTATGACATTTTCCTAAAGGACTTGGAGCCGCCCATTGTAGCCAGATTTGTCCGG TTCATTCCAGTCACCGACCACTCCATGAATGTGTGTATGAGAGTGGAGCTTTACGGCTGTGTCTGGCTAGATGGCTTGGTGTCTTACAAT GCTCCAGCTGGGCAGCAGTTTGTACTCCCTGGAGGTTCCATCATTTATCTGAATGATTCTGTCTATGATGGAGCTGTTGGATACAGCATG ACAGAAGGGCTAGGCCAATTGACCGATGGTGTGTCTGGCCTGGACGATTTCACCCAGACCCATGAATACCACGTGTGGCCCGGCTATGAC TATGTGGGCTGGCGGAACGAGAGTGCCACCAATGGCTACATTGAGATCATGTTTGAATTTGACCGCATCAGGAATTTCACTACCATGAAG GTCCACTGCAACAACATGTTTGCTAAAGGTGTGAAGATCTTTAAGGAGGTACAGTGCTACTTCCGCTCTGAAGCCAGTGAGTGGGAACCT AATGCCATTTCCTTCCCCCTTGTCCTGGATGACGTCAACCCCAGTGCTCGGTTTGTCACGGTGCCTCTCCACCACCGAATGGCCAGTGCC ATCAAGTGTCAATACCATTTTGCAGATACCTGGATGATGTTCAGTGAGATCACCTTCCAATCAGATGCTGCAATGTACAACAACTCTGAA GCCCTGCCCACCTCTCCTATGGCACCCACAACCTATGATCCAATGCTTAAAGTTGATGACAGCAACACTCGGATCCTGATTGGCTGCTTG GTGGCCATCATCTTTATCCTCCTGGCCATCATTGTCATCATCCTCTGGAGGCAGTTCTGGCAGAAAATGCTGGAGAAGGCTTCTCGGAGG ATGCTGGATGATGAAATGACAGTCAGCCTTTCCCTGCCAAGTGATTCTAGCATGTTCAACAATAACCGCTCCTCATCACCTAGTGAACAA GGGTCCAACTCGACTTACGATCGCATCTTTCCCCTTCGCCCTGACTACCAGGAGCCATCCAGGCTGATACGAAAACTCCCAGAATTTGCT CCAGGGGAGGAGGAGTCAGGCTGCAGCGGTGTTGTGAAGCCAGTCCAGCCCAGTGGCCCTGAGGGGGTGCCCCACTATGCAGAGGCTGAC ATAGTGAACCTCCAAGGAGTGACAGGAGGCAACACATACTCAGTGCCTGCCGTCACCATGGACCTGCTCTCAGGAAAAGATGTGGCTGTG GAGGAGTTCCCCAGGAAACTCCTAACTTTCAAAGAGAAGCTGGGAGAAGGACAGTTTGGGGAGGTTCATCTCTGTGAAGTGGAGGGAATG GAAAAATTCAAAGACAAAGATTTTGCCCTAGATGTCAGTGCCAACCAGCCTGTCCTGGTGGCTGTGAAAATGCTCCGAGCAGATGCCAAC AAGAATGCCAGGAATGATTTTCTTAAGGAGATAAAGATCATGTCTCGGCTCAAGGACCCAAACATCATCCATCTATTAGCTGTGTGTATC ACTGATGACCCTCTCTGTATGATCACTGAATACATGGAGAATGGAGATCTCAATCAGTTTCTTTCCCGCCACGAGCCCCCTAATTCTTCC TCCAGCGATGTACGCACTGTCAGTTACACCAATCTGAAGTTTATGGCTACCCAAATTGCCTCTGGCATGAAGTACCTTTCCTCTCTTAAT TTTGTTCACCGAGATCTGGCCACACGAAACTGTTTAGTGGGTAAGAACTACACAATCAAGATAGCTGACTTTGGAATGAGCAGGAACCTG TACAGTGGTGACTATTACCGGATCCAGGGCCGGGCAGTGCTCCCTATCCGCTGGATGTCTTGGGAGAGTATCTTGCTGGGCAAGTTCACT ACAGCAAGTGATGTGTGGGCCTTTGGGGTTACTTTGTGGGAGACTTTCACCTTTTGTCAAGAACAGCCCTATTCCCAGCTGTCAGATGAA CAGGTTATTGAGAATACTGGAGAGTTCTTCCGAGACCAAGGGAGGCAGACTTACCTCCCTCAACCAGCCATTTGTCCTGACTCTGTGTAT AAGCTGATGCTCAGCTGCTGGAGAAGAGATACGAAGAACCGTCCCTCATTCCAAGAAATCCACCTTCTGCTCCTTCAACAAGGCGACGAG >In-frame_RFWD2_ENST00000308769_chr1_175996708_-_DDR2_ENST00000367921_chr1_162722885_+_4143nt ATGTCTGGTAGCCGCCAGGCCGGGTCGGGCTCCGCTGGGACAAGCCCCGGGTCCTCGGCGGCCTCCTCGGTGACTTCCGCCTCCTCGTCT TTATCCTCTTCCCCGTCGCCGCCTTCCGTGGCGGTTTCGGCGGCAGCGCTGGTGTCCGGCGGGGTGGCCCAGGCCGCCGGCTCGGGCGGC CTCGGGGGCCCGGTGCGGCCTGTGTTGGTGGCGCCCGCCGTATCGGGTAGCGGCGGCGGGGCGGTGTCCACGGGCCTGTCCCGGCACAGC TGCGCGGCCAGGCCCAGCGCCGGCGTAGGAGGCAGCAGCTCCAGCCTAGGCAGCGGCAGCAGGAAGCGACCTCTCCTCGCCCCCCTCTGC AACGGGCTCATCAACTCCTACGAGGACAAAAGCAACGACTTCGTATGCCCCATCTGCTTTGATATGATTGAAGAAGCATACATGACAAAA TGTGGCCACAGCTTTTGCTACAAGTGTATTCATCAGAGTTTGGAGGACAATAATAGATGTCCCAAGTGTAACTATGTTGTGGACAATATT GACCATCTGTATCCTAATTTCTTGGTGAATGAACTCATTCTTAAACAGAAGCAAAGATTTGAGGAAAAGAGGTTCAAATTGGACCACTCA AATGGCCACAGGTGGCAGATATTTCAAGATTGGTTGGGAACTGACCAAGATAACCTTGATTTGGCCAATGTCAATCTTATGTTGGAGTTA CTAGTGCAGAAGAAGAAACAACTGGAAGCAGAATCACATGCAGCCCAACTACAGATTCTTATGGAATTCCTCAAGGTTGCAAGAAGAAAT AAGAGAGAGGAAATGAGTGGCTTATACTCTCCTGTCAGTGAGGATAGCACAGTGCCTCAATTTGAAGCTCCTTCTCCATCACACAGTAGT ATTATTGATTCCACAGAATACAGCCAACCTCCAGGTTTCAGTGGCAGTTCTCAGACAAAGAAACAGCCTTGGTATAATAGCACGTTAGCA TCAAGACGAAAACGACTTACTGCTCATTTTGAAGACTTGGAGCAGTGTTACTTTTCTACAAGGATGTCTCGTATCTCAGATGACAGTCGA ACTGCAAGCCAGTTGGATGAATTTCAGGAATGCTTGTCCAAGTTTACTCGATATAATTCAGTACGACCTTTAGCCACATTGTCATATGCT AGTGATCTCTATAATGGTTCCAGTATAGTCTCTAGTATTGAATTTGACCGGGATTGTGACTATTTTGCGATTGCTGGAGTTACAAAGAAG ATTAAAGTCTATGAATATGACACTGTCATCCAGGATGCAGTGGATATTCATTACCCTGAGAATGAAATGACCTGCAATTCGAAAATCAGC TGTATCAGTTGGAGTAGTTACCATAAGAACCTGTTAGCTAGCAGTGATTATGAAGGCACTGTTATTTTATGGGATGGATTCACAGGACAG AGGTCAAAGGTCTATCAGGAGCATGAGAAGAGGTGTTGGAGTGTTGACTTTAATTTGATGGATCCTAAACTCTTGGCTTCAGGTTCTGAT GATGCAAAAGTGAAGCTGTGGTCTACCAATCTAGACAACTCAGTGGCAAGCATTGAGGCAAAGGCTAATGTGTGCTGTGTTAAATTCAGC CCCTCTTCCAGATACCATTTGGCTTTCGGCTGTGCAGCTATATGCCGCTATCCTCTGGGCATGTCAGGAGGCCAGATTCCAGATGAGGAC ATCACAGCTTCCAGTCAGTGGTCAGAGTCCACAGCTGCCAAATATGGAAGGCTGGACTCAGAAGAAGGGGATGGAGCCTGGTGCCCTGAG ATTCCAGTGGAACCTGATGACCTGAAGGAGTTTCTGCAGATTGACTTGCACACCCTCCATTTTATCACTCTGGTGGGGACCCAGGGGCGC CATGCAGGAGGTCATGGCATCGAGTTTGCCCCCATGTACAAGATCAATTACAGTCGGGATGGCACTCGCTGGATCTCTTGGCGGAACCGT CATGGGAAACAGGTGCTGGATGGAAATAGTAACCCCTATGACATTTTCCTAAAGGACTTGGAGCCGCCCATTGTAGCCAGATTTGTCCGG TTCATTCCAGTCACCGACCACTCCATGAATGTGTGTATGAGAGTGGAGCTTTACGGCTGTGTCTGGCTAGATGGCTTGGTGTCTTACAAT GCTCCAGCTGGGCAGCAGTTTGTACTCCCTGGAGGTTCCATCATTTATCTGAATGATTCTGTCTATGATGGAGCTGTTGGATACAGCATG ACAGAAGGGCTAGGCCAATTGACCGATGGTGTGTCTGGCCTGGACGATTTCACCCAGACCCATGAATACCACGTGTGGCCCGGCTATGAC TATGTGGGCTGGCGGAACGAGAGTGCCACCAATGGCTACATTGAGATCATGTTTGAATTTGACCGCATCAGGAATTTCACTACCATGAAG GTCCACTGCAACAACATGTTTGCTAAAGGTGTGAAGATCTTTAAGGAGGTACAGTGCTACTTCCGCTCTGAAGCCAGTGAGTGGGAACCT AATGCCATTTCCTTCCCCCTTGTCCTGGATGACGTCAACCCCAGTGCTCGGTTTGTCACGGTGCCTCTCCACCACCGAATGGCCAGTGCC ATCAAGTGTCAATACCATTTTGCAGATACCTGGATGATGTTCAGTGAGATCACCTTCCAATCAGATGCTGCAATGTACAACAACTCTGAA GCCCTGCCCACCTCTCCTATGGCACCCACAACCTATGATCCAATGCTTAAAGTTGATGACAGCAACACTCGGATCCTGATTGGCTGCTTG GTGGCCATCATCTTTATCCTCCTGGCCATCATTGTCATCATCCTCTGGAGGCAGTTCTGGCAGAAAATGCTGGAGAAGGCTTCTCGGAGG ATGCTGGATGATGAAATGACAGTCAGCCTTTCCCTGCCAAGTGATTCTAGCATGTTCAACAATAACCGCTCCTCATCACCTAGTGAACAA GGGTCCAACTCGACTTACGATCGCATCTTTCCCCTTCGCCCTGACTACCAGGAGCCATCCAGGCTGATACGAAAACTCCCAGAATTTGCT CCAGGGGAGGAGGAGTCAGGCTGCAGCGGTGTTGTGAAGCCAGTCCAGCCCAGTGGCCCTGAGGGGGTGCCCCACTATGCAGAGGCTGAC ATAGTGAACCTCCAAGGAGTGACAGGAGGCAACACATACTCAGTGCCTGCCGTCACCATGGACCTGCTCTCAGGAAAAGATGTGGCTGTG GAGGAGTTCCCCAGGAAACTCCTAACTTTCAAAGAGAAGCTGGGAGAAGGACAGTTTGGGGAGGTTCATCTCTGTGAAGTGGAGGGAATG GAAAAATTCAAAGACAAAGATTTTGCCCTAGATGTCAGTGCCAACCAGCCTGTCCTGGTGGCTGTGAAAATGCTCCGAGCAGATGCCAAC AAGAATGCCAGGAATGATTTTCTTAAGGAGATAAAGATCATGTCTCGGCTCAAGGACCCAAACATCATCCATCTATTAGCTGTGTGTATC ACTGATGACCCTCTCTGTATGATCACTGAATACATGGAGAATGGAGATCTCAATCAGTTTCTTTCCCGCCACGAGCCCCCTAATTCTTCC TCCAGCGATGTACGCACTGTCAGTTACACCAATCTGAAGTTTATGGCTACCCAAATTGCCTCTGGCATGAAGTACCTTTCCTCTCTTAAT TTTGTTCACCGAGATCTGGCCACACGAAACTGTTTAGTGGGTAAGAACTACACAATCAAGATAGCTGACTTTGGAATGAGCAGGAACCTG TACAGTGGTGACTATTACCGGATCCAGGGCCGGGCAGTGCTCCCTATCCGCTGGATGTCTTGGGAGAGTATCTTGCTGGGCAAGTTCACT ACAGCAAGTGATGTGTGGGCCTTTGGGGTTACTTTGTGGGAGACTTTCACCTTTTGTCAAGAACAGCCCTATTCCCAGCTGTCAGATGAA CAGGTTATTGAGAATACTGGAGAGTTCTTCCGAGACCAAGGGAGGCAGACTTACCTCCCTCAACCAGCCATTTGTCCTGACTCTGTGTAT AAGCTGATGCTCAGCTGCTGGAGAAGAGATACGAAGAACCGTCCCTCATTCCAAGAAATCCACCTTCTGCTCCTTCAACAAGGCGACGAG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_RFWD2_ENST00000367669_chr1_175996708_-_DDR2_ENST00000367922_chr1_162722885_+_11884nt CACCTATACCATTCATTCCAGTCTCCTCAATTCTTTCACTGTATTAAGACGGCCTGCCCTCTGGCACGTTTTCTGGAACGAAAGCGGCTT GGGACAGACAGACTCCCTTCGCCAGGGAGCCCCGACCCCGAGGGCGCGCCCTGAGCGTCTGAGCGCAGCCCCGCTGCGTCCCCAGTTGTA TCCCCCGCCACGCCCGCCTCTTCCGCCGCTCGCGCGCGCGCGCACGGCCGGCCACGGCGCGCCGGGGTTGGCTGCTACAGGGACCGCGGT GGCGGCGGCGGCCTCGACAGCGGTAGTGCCTTCTACTCCGCTTTTTTAGTTTCCTCCGCCCCCTCCCGTGGGACGCTGTTGTGTGGCTGC CTTAAAAAAAAACGCAACTTTATTGTTCCTCAGCCCCACCTCCGGCTCGGCGGGCGTCCTCAGGATGCACTGAGGCTGAGGGGAGGGGAG GCGGCGGAGGGTCGAGGTCGCGGTCCCTCTCCTCCGAGCGCCCGGCTGGAGGGGAGGGAGTCACGATGTCTGGTAGCCGCCAGGCCGGGT CGGGCTCCGCTGGGACAAGCCCCGGGTCCTCGGCGGCCTCCTCGGTGACTTCCGCCTCCTCGTCTTTATCCTCTTCCCCGTCGCCGCCTT CCGTGGCGGTTTCGGCGGCAGCGCTGGTGTCCGGCGGGGTGGCCCAGGCCGCCGGCTCGGGCGGCCTCGGGGGCCCGGTGCGGCCTGTGT TGGTGGCGCCCGCCGTATCGGGTAGCGGCGGCGGGGCGGTGTCCACGGGCCTGTCCCGGCACAGCTGCGCGGCCAGGCCCAGCGCCGGCG TAGGAGGCAGCAGCTCCAGCCTAGGCAGCGGCAGCAGGAAGCGACCTCTCCTCGCCCCCCTCTGCAACGGGCTCATCAACTCCTACGAGG ACAAAAGCAACGACTTCGTATGCCCCATCTGCTTTGATATGATTGAAGAAGCATACATGACAAAATGTGGCCACAGCTTTTGCTACAAGT GTATTCATCAGAGTTTGGAGGACAATAATAGATGTCCCAAGTGTAACTATGTTGTGGACAATATTGACCATCTGTATCCTAATTTCTTGG TGAATGAACTCATTCTTAAACAGAAGCAAAGATTTGAGGAAAAGAGGTTCAAATTGGACCACTCAGTGAGTAGCACCAATGGCCACAGGT GGCAGATATTTCAAGATTGGTTGGGAACTGACCAAGATAACCTTGATTTGGCCAATGTCAATCTTATGTTGGAGTTACTAGTGCAGAAGA AGAAACAACTGGAAGCAGAATCACATGCAGCCCAACTACAGATTCTTATGGAATTCCTCAAGGTTGCAAGAAGAAATAAGAGAGAGCAAC TGGAACAGATCCAGAAGGAGCTAAGTGTTTTGGAAGAGGATATTAAGAGAGTGGAAGAAATGAGTGGCTTATACTCTCCTGTCAGTGAGG ATAGCACAGTGCCTCAATTTGAAGCTCCTTCTCCATCACACAGTAGTATTATTGATTCCACAGAATACAGCCAACCTCCAGGTTTCAGTG GCAGTTCTCAGACAAAGAAACAGCCTTGGTATAATAGCACGTTAGCATCAAGACGAAAACGACTTACTGCTCATTTTGAAGACTTGGAGC AGTGTTACTTTTCTACAAGGATGTCTCGTATCTCAGATGACAGTCGAACTGCAAGCCAGTTGGATGAATTTCAGGAATGCTTGTCCAAGT TTACTCGATATAATTCAGTACGACCTTTAGCCACATTGTCATATGCTAGTGATCTCTATAATGGTTCCAGTATAGTCTCTAGTATTGAAT TTGACCGGGATTGTGACTATTTTGCGATTGCTGGAGTTACAAAGAAGATTAAAGTCTATGAATATGACACTGTCATCCAGGATGCAGTGG ATATTCATTACCCTGAGAATGAAATGACCTGCAATTCGAAAATCAGCTGTATCAGTTGGAGTAGTTACCATAAGAACCTGTTAGCTAGCA GTGATTATGAAGGCACTGTTATTTTATGGGATGGATTCACAGGACAGAGGTCAAAGGTCTATCAGGAGCATGAGAAGAGGTGTTGGAGTG TTGACTTTAATTTGATGGATCCTAAACTCTTGGCTTCAGGTTCTGATGATGCAAAAGTGAAGCTGTGGTCTACCAATCTAGACAACTCAG TGGCAAGCATTGAGGCAAAGGCTAATGTGTGCTGTGTTAAATTCAGCCCCTCTTCCAGATACCATTTGGCTTTCGGCTGTGCAGCTATAT GCCGCTATCCTCTGGGCATGTCAGGAGGCCAGATTCCAGATGAGGACATCACAGCTTCCAGTCAGTGGTCAGAGTCCACAGCTGCCAAAT ATGGAAGGCTGGACTCAGAAGAAGGGGATGGAGCCTGGTGCCCTGAGATTCCAGTGGAACCTGATGACCTGAAGGAGTTTCTGCAGATTG ACTTGCACACCCTCCATTTTATCACTCTGGTGGGGACCCAGGGGCGCCATGCAGGAGGTCATGGCATCGAGTTTGCCCCCATGTACAAGA TCAATTACAGTCGGGATGGCACTCGCTGGATCTCTTGGCGGAACCGTCATGGGAAACAGGTGCTGGATGGAAATAGTAACCCCTATGACA TTTTCCTAAAGGACTTGGAGCCGCCCATTGTAGCCAGATTTGTCCGGTTCATTCCAGTCACCGACCACTCCATGAATGTGTGTATGAGAG TGGAGCTTTACGGCTGTGTCTGGCTAGATGGCTTGGTGTCTTACAATGCTCCAGCTGGGCAGCAGTTTGTACTCCCTGGAGGTTCCATCA TTTATCTGAATGATTCTGTCTATGATGGAGCTGTTGGATACAGCATGACAGAAGGGCTAGGCCAATTGACCGATGGTGTGTCTGGCCTGG ACGATTTCACCCAGACCCATGAATACCACGTGTGGCCCGGCTATGACTATGTGGGCTGGCGGAACGAGAGTGCCACCAATGGCTACATTG AGATCATGTTTGAATTTGACCGCATCAGGAATTTCACTACCATGAAGGTCCACTGCAACAACATGTTTGCTAAAGGTGTGAAGATCTTTA AGGAGGTACAGTGCTACTTCCGCTCTGAAGCCAGTGAGTGGGAACCTAATGCCATTTCCTTCCCCCTTGTCCTGGATGACGTCAACCCCA GTGCTCGGTTTGTCACGGTGCCTCTCCACCACCGAATGGCCAGTGCCATCAAGTGTCAATACCATTTTGCAGATACCTGGATGATGTTCA GTGAGATCACCTTCCAATCAGATGCTGCAATGTACAACAACTCTGAAGCCCTGCCCACCTCTCCTATGGCACCCACAACCTATGATCCAA TGCTTAAAGTTGATGACAGCAACACTCGGATCCTGATTGGCTGCTTGGTGGCCATCATCTTTATCCTCCTGGCCATCATTGTCATCATCC TCTGGAGGCAGTTCTGGCAGAAAATGCTGGAGAAGGCTTCTCGGAGGATGCTGGATGATGAAATGACAGTCAGCCTTTCCCTGCCAAGTG ATTCTAGCATGTTCAACAATAACCGCTCCTCATCACCTAGTGAACAAGGGTCCAACTCGACTTACGATCGCATCTTTCCCCTTCGCCCTG ACTACCAGGAGCCATCCAGGCTGATACGAAAACTCCCAGAATTTGCTCCAGGGGAGGAGGAGTCAGGCTGCAGCGGTGTTGTGAAGCCAG TCCAGCCCAGTGGCCCTGAGGGGGTGCCCCACTATGCAGAGGCTGACATAGTGAACCTCCAAGGAGTGACAGGAGGCAACACATACTCAG TGCCTGCCGTCACCATGGACCTGCTCTCAGGAAAAGATGTGGCTGTGGAGGAGTTCCCCAGGAAACTCCTAACTTTCAAAGAGAAGCTGG GAGAAGGACAGTTTGGGGAGGTTCATCTCTGTGAAGTGGAGGGAATGGAAAAATTCAAAGACAAAGATTTTGCCCTAGATGTCAGTGCCA ACCAGCCTGTCCTGGTGGCTGTGAAAATGCTCCGAGCAGATGCCAACAAGAATGCCAGGAATGATTTTCTTAAGGAGATAAAGATCATGT CTCGGCTCAAGGACCCAAACATCATCCATCTATTAGCTGTGTGTATCACTGATGACCCTCTCTGTATGATCACTGAATACATGGAGAATG GAGATCTCAATCAGTTTCTTTCCCGCCACGAGCCCCCTAATTCTTCCTCCAGCGATGTACGCACTGTCAGTTACACCAATCTGAAGTTTA TGGCTACCCAAATTGCCTCTGGCATGAAGTACCTTTCCTCTCTTAATTTTGTTCACCGAGATCTGGCCACACGAAACTGTTTAGTGGGTA AGAACTACACAATCAAGATAGCTGACTTTGGAATGAGCAGGAACCTGTACAGTGGTGACTATTACCGGATCCAGGGCCGGGCAGTGCTCC CTATCCGCTGGATGTCTTGGGAGAGTATCTTGCTGGGCAAGTTCACTACAGCAAGTGATGTGTGGGCCTTTGGGGTTACTTTGTGGGAGA CTTTCACCTTTTGTCAAGAACAGCCCTATTCCCAGCTGTCAGATGAACAGGTTATTGAGAATACTGGAGAGTTCTTCCGAGACCAAGGGA GGCAGACTTACCTCCCTCAACCAGCCATTTGTCCTGACTCTGTGTATAAGCTGATGCTCAGCTGCTGGAGAAGAGATACGAAGAACCGTC CCTCATTCCAAGAAATCCACCTTCTGCTCCTTCAACAAGGCGACGAGTGATGCTGTCAGTGCCTGGCCATGTTCCTACGGCTCAGGTCCT CCCTACAAGACCTACCACTCACCCATGCCTATGCCACTCCATCTGGACATTTAATGAAACTGAGAGACAGAGGCTTGTTTGCTTTGCCCT CTTTTCCTGGTCACCCCCACTCCCTACCCCTGACTCATATACACTTTTTTTTTTTTTTACATTAAAGAACTAAAAAAGGAAAAAAAAAAG CCTAGGGCAGATACAATCTAGTAAAAGAAAATCTTTGATATACCAAAGTGTTGGATAACAAAGGCTAGAAAATTCAGATAATTTATAAAG GTTAACTATACTTGTGCTTATAAATGTGCAGATTCTACAATATTTTTCCATGTCATTCTAAAAGAATCTTCAGAAAGAAAAACTTGAAGA ATACTAATGTCTTGGGAAACATGAGATTAAGTTTAGGGAAAACACTTGATAGATGTGGAGAATCTGAGGACTCAGAATTCAGCAACTAAT CACAGGTGGTTTTCTAATTTGGCCTCTGGACATGTCTCACTGTTTGTATTTCTCTCTCCTGTCAAAGTGAATGATATATTCTTGAAAACC CCCAATTTCTTGAAATGGGTGTTCTGTTCATTCATGGGCAGGGGTCAGGATTGAAGTTCATATATGAAACAACTGGGGATGTAGATAGGA AAGAATGTCTGCTGCAAGAGTGTATGAAGGGGGATTGTCATTTACAAAAAAAAAGTACCTCATGGATGGAAGGATTCATGAATAGATAAT GGACATAGGAAAGGAGGTCAATGGAGGACACATAACAGACATGCTATCCACCATTTATTTGTGATTTTGTAAGAGGGTTCTCTTCTTTGT CTTGTTCAGATATTTTCATGTGTGTGTTTTAGTGAGAATCTGAGTTTTTAATCAGTAAAGTCTGATGTTTTGATATCTTGATGTTTTGAT GGTAGACTCTTGAGTTCATCTTGTCCAAATCTTCTAGCATTTTCAAGGATGAAGCCTCTGTGGGATCTTTGGGCTTGGGGCTGAATTTCT CAGGCATAAATACCTAATGGCCTTGTCTAAGAGGGAATAGATCTGTTCTGAGTGTCCCCAAAAAAGTTGTCCTAGGAACTGATGTGGAGA AGTTACAGGGAGACTGATTTCCATTCCTTATTGGGGAAAACGAAGCACTCAGAACATACAAGGATAAATGGGCTGCCACCAGAGGTGAGG AGTCTCTTGTCACTGGAGAGGTTAAGATAGAGGCTCAAGAACAATGCAAGGAAAATGGAGGTTTTCAAACACAAAGTGGATGGTGGTATG AGACAATGTTTAATGTCCTTCTAACTCCGAGAGTCCTTGATTCTGGAGAGGCACAGGATGAACATCTGTTGCTACTGCTGAGTATACACA CTCTTGCCTCTGAGATGGCGTGACCAGCAGAAAAGAAAGCTCAGGGCTGTGGCTTCAGAATTCATGGAAACAGAGCCACTGTCAAGAAGG AATCTGCTCAGAGCAGATTCTGAGTTTTCACACTCCACAAATCCTCAGATTTAGTGGGAAGCTGGAAAAAGGAACTCTTAATTCCAATTG AGGAGAAACAAGAAAACATTACAAATCAGTTTCCCAAGCTGAGAAGGATTAGCCTTGACCCCTTGGGTCTGCCTCTGTTGCCCTCACCAG TTTACCTTCTACAACAGTTTCTCAGGAACATGTGTATTTCCCCATTCAGCTTTCAGCATTGCTCCACGCCACAGCATAAGCATAGATCCC AAGTCCACAGGCTCCATTTTGCAGGTCATCTTCTGATCCTAGCAAATGTCCTTTCCCCATAGTTGTCCTATGCCTTTGGGCTTTAGTCTA TCCCAGGACTAACTGTGGAGAAATCATTGGTTTGAGAGTCAAGAGAGCATTGGTTTGGGAGCTTTAATCCTCTTTCTGCTTCACACTAAG TGTGTCATCTTGGCTAAATCACTTGGTCTTTCTGCATTTTGTTTTCTTATTTATAGGATGAGGAAATTAGATTAAATGGTTTTGAGGTCC TTTCTTGTTCTGATATGTCCAGTACTCACTGGAAAATTGGATCTATAACTGATGGGTTTAGTAATCTGGTCATTTCTTGCTCTGAAAATT GTAGTCAGCAAAAGAGATCATGGAAGAAATCACTGTAATGGTAGTAATAGTAACACATGCCATTTGTATTGTGCCTTAGGTTTACCAGGT GTTTCCAAATACATTAGCATATTTGATATGTGCAGGACTAGATACCTTGGGACCTGCCACACTCCACTTTCAAGATATGTATTAGCTTCA TTAGAATTAAAGGGACTTGAACTCAGGACCTGCAGCCTATTCTTCTTTATCCACATGTCTCTGGTAGGGCTACATCCAGATCACACCATG ACTTCTTATAGAGCAAGAGAAAATAATATTATTATATCTTCCTTTGCCTAAAATCTCTCCACTTATTCTTTTTTATGATTCTGCACCAGT TCACTGGGTTATTCTATGATTCCATATTTTTTTTAAAAAAAATCATATTTAAAATGAACTTACAATGTCTGAATTTTCCTGGCCTTGAGT CACAGAAGTAATATGTTTCAGATGGCTGCCCAATATGTATTATCATGTAATACATATCTGTGTCCTTTTCTGGGATGAGGAAGGCTTCAA CTTCTGGCACTGAGAACTTTGTATTACAGACACAGGTTTAGTTTCTAGCTTAGTCATGCCTTTAGAGTTTAGTAGCACAAATCCATGCAA CCCAACAGAATACATGGTGAGGGCCTAGTATGTAGAATTTGAAAGTAGTTCAAATTTGAATTAGAAGAATGAAGCTAGGACTTATTTGGA AAAGGAGATAGAAAAAAAATGATCAGAAACTGTGGGGCCTTATTACCTTTGCAGTAAGTTATCTTCTTCATGATATATGTGAATTATTTT ATGTGCAGATTGTGTTTTGGGATTGTCAGATCTAAACTTATATTCTTGCTGGCTAATGTGCTGATAGCCAGGTCTGAAACTTGATGTGCT ATCCAGACACATATGATCAGAAAAGATCTAGAGTGCAAAGAGGTGCCTGAGGAGCAAAATGTGGTTTTAATGTTGTGGAAAGATCACTTG CAAGTATATAAGACTGTATAAAGAAGAGGACTGTGTGCAAGTGGGGTGAAAAAAAAGGATACGTGAATGTGCATATGACTGAATAGGGAG GAAGGTCAGGGCTAGAAAGGAGGCTACATAAAAAGGGGCAATGGAGAATGCACAGGAAAGACACAGGGGAAGGTCAAGTCGAGCAAGGTA GAAACAGGAGTAGCTAGAGCCATTGGGAATCCATTTTGAAACAAGAAGGAGTTTTGAAAGGGAATAGGAAAGTAAGTGTCTTGAAGTAAA AGATAAATATGGATGGAGAAAGAAGAAATTCTGGATGATAGAGATGATAAAAATATTTATTAAGAAATGAAGTCAGGTTCAGTGTATGAA ATGGAAAGGAATTTTTCAGAATTTTAAGAAAGGGGAAGTTCCTCTTGGAAAAGATATAGCAACCATCGGGGAATGACCTTTTCATTTCAG AAGTGGATGAGGAAGGTGGTGTGAGCATCAGGTATATTCTGGACCATTTCAAGTGCTGGTGAGAAGAAAGGAACTCTTTGCCTGAACTGG GCTTGGTTTTCCAAGTGCTGCTTTGGAAATGAAGACCCAGAGATGCAGAGCTTATGGTAGTTCATAAATCTTCATGTTCTATTATCTTTC ATCTGCCAATAAAGTTCATTTTCAATAATGTCCACCATTGCTGTGCCCAGAATAACCACAGGCAAACATCAAAACAATACGCATAAGTTA GACAAGATTAAATCTTGTCTGATATCTGCACAAACAGATATGCACCATGTTGGAAACATGTGTTTTCCTAGTCCCATCCAGGCTTCCCAC AAGAAAGCCATGATGTGGGTCTAAACCATATGTTTTGAGTAAAGGAGAATAGAAGAAGGGGAGTGTCCGCAAAATGGAAAGAGATGAAGA TGTTCCAAGGAAGTATGCTGAAACAGAACAGTGAATGTTTTGCCCAAAACTACAAAAATAAAAGAAAAAAAGAAAATTGCAATACATGGC TACTAAGTCTTTGATCATAAGTCGAATTTATAGACCTGGAATTTGCCATCCTAGTCTTTCCTTTTTAGTAAGACTTCTGTCCTCTGGCAG TGCATATGGTAGGTCTCTAATGTTTCTTCATCTCCAGGAAGATGCAGATCCTTATTTTTGCTGGGAAATCCTTCTAAATAGAAATGTAAC ATTTTTATAAAAACAGATTAATGTGTTTTTCACTTAGTAAATGTTTTCAAGAGCTGAATTGAGAAGGAAAGAGACTGGAGTGGTTAATGG TGATTTGATTTCTGGCATTCTGAGTTTTCTGCTACAATTAGCTGCATTACTTGGTGCCAAAGAGCAGTGGGGAATTGTTGAGTTGCTGTA TCCTTTAAAAAAAAACAAAAAACTTGTTATTTTGAAAGAACTTAAGGCTCACAAGATGTTACAAAAATAGTAGAGTGGCCTTACCCTAGA TCCAGTTTTCCCCATTTATAACATTTCACTTAGTCCATTTTCGGAACCAGAAAATTAACATTGGCATAATGCTATTAACTAAACTACAGA CCTTTTTTCAATTTCGCCAGTTTTTCCACACATATTCATTTAGTTGCTGGATACTTTTAATTCTTGCTGATTTGTAAACTGGCCTTGCTT GGATACAACAGGAAAGATACTATCTGGATAAAGTTCTACAGTTTTAGAGAGACTATTAACACATTAATGTGTTCCTTTGTCATGAGCAAT ACCCTGCCTACACTGCTTCTAAATTTTCTGATTTGTTTGGCTGTTTGGCATCTGAAACAATCCAAGACAAACTTAGAAAGATTAGGCAAC ACAAAACACAGTAAGACCTGTTCATAGCTTGTTGTCTAGAAAACCAGGTAGCAGGATATTCTAGATGCTTCCTGCTGCTTCTACGTGAGT AGGATTAGCACTGGGGACAAAATAAGGAGTTTAGAGTAAACCAGTATTTCAGTCAAGAGTTAGTTGGCACTTAGTTAATGGCACTGGAAA TAGCTTGTGGAGAGAATAGAATACAATGGTATAGACTCCTAATGTTTGATAAAATACTATTTTCAGAGTGGTAGAGAGGTTTTATTTGCC TAAATAGCCGTTATTAAATGGAATAACAACCACATTAGACCAAATTAATTGCAAACACAGCGGCAACCTGGGGAGAAGTTGAAACTCCAG TTTTGTGGATTACAGTTTTGAGTTTTATGATTGACATTTTTAAGTCCCCTATTTAAGGGGTCAAGATTATAACAATGTGTGTCTTACTAA GTTTCTAGGTCATTGTGAGCACTTGATAAATATTTGCTGAATGTTGTTTTTTTGAATGAACATAAGATAGAAACAAAAACTTCTCATCCA GTTAACTAGAGTGAATGTAGGGAGAATTGTTTTGCTTGTAACATGGAGAGTTTATTTTCAAGTGAGGAAAGAGAAAAAAATTACTCAGAC TTGTTCCTGGTGAAGTGCATTCTCTGTTTGTATACTTTTTGATGGAGAAATTGATCTATAGAACTGCTTAATTTTTTGAGGCATTTAGAC AGCAATGAAAGGTAGTTCTCCACAGGACACCGAATCAAAAGGAGAGACCAGACTCTGGCCTCATACCCAGCCTATTTGAAACAAGCTATC TAGTTTCTCCTGCAGACACCTTGTCAACAACATGCAACAGTGTCAGGTGCCTTGCAGGAAAATAATCTGAGTCCCAAGCTAGCCTGTGCT CATCCACAATCACAATGAACATGTCAAGGAAGAATTTGCAGAGACTCAAGGGAAGCACAATGGGATAAGGTAATCACTTTCAGTGAAAAA CTGTTTTCTTGAAAACAGGCTTGGACACAATTGAAAGCTGGCTTCCTGCAAACACACCAAGAGTCTGTAATCTAGCCTATCCATTATATG TCCTTTATTATTCATGATATCCTATTCTTCTACCTTGTTGCCTGGTAACTTTTTCTGAGGACTGAGTTTCTGCAGCGATGTGGTGCACTC TTCCTGTGATGAGGAAACATCTGGGCCCCCTTCTGCAGGCTTTGGAAGATGATGTGTCTTGTCAAGGGGTAAAGGGCAAATGGATTTAAT TTCTGCTTAAAACTATCATAGACGTTCCAAATAGAATATGTAAAATTTCTCTGTATTAGAAAAAGAAACGTGATACCAATTGTATATTTT CTTTTCTTTATTTATTCTCTGTAAGTCTGTCAGATGATAAATTGTAAATAACAATGATTAAAGAGTCATGCTACTGATGGATCTCCCTTT CTGTATAAACAGTGCCAGTTCTGGGCTTTGTAACCTTTGCTCTTTATAGTCTTTCATTCCTGGGGAAGTGATGGGGCATGGGCCCAGAGC TGGGGTGTATGTGGTATGGACACCTGTTTGTGGGGCTTTCCAGCAAAGGATTATTTAAATAGACCTCTAACATATGAGTTGACTGTTTAT TGGGAAGAAAGCATCTTGGTCTCTGACATATCCAAACATACGAGACACTGGGATTTTACGTCCTCACATTAATTAGTCCAGTTCTGGGGA ATCCAGTCTAGAATTAACTGGTGATCCCTTATCGTTATGGTTACAGACTTGTCTTGTTTGATACACAGAAATCCTTTTTAAATCCAAATA TAGTCTGTCTCAGACTACCTGCACATGCACAAACCAAAAAAAACTATGAAAACCAGAATTTAGACTCAGTCATTATACTAGAGATTAGAA TGAAACGACCCCAAACAACCCATTTCTTACCTGGTCTCTGAGAATAAGTTTATACTTTTAGTTTTCTGAGAATATTTCTCAGAATATGTG AGTTTTCTGAGCACATTTTTCAGCATGGGGTATGGTAGATAAATCACAGGGCCAAGGTTTGGCAGGGATAGATGGGATCATTGTGTACCC TATTGTTCTTCTGATTTCCAGGAGAACAGAATGAGCCCATGCAAAACATAAACTTATGATGATTAAAAAAAACACACCTATCCATTCACT CATCAATAAAAACATATTATGATGGTTATCAAGCTGTGTCCTATGAGTGATAAAATATTTGTAAAATATAAAATTAAATGGCATCTATTT >In-frame_RFWD2_ENST00000367669_chr1_175996708_-_DDR2_ENST00000367921_chr1_162722885_+_4905nt CACCTATACCATTCATTCCAGTCTCCTCAATTCTTTCACTGTATTAAGACGGCCTGCCCTCTGGCACGTTTTCTGGAACGAAAGCGGCTT GGGACAGACAGACTCCCTTCGCCAGGGAGCCCCGACCCCGAGGGCGCGCCCTGAGCGTCTGAGCGCAGCCCCGCTGCGTCCCCAGTTGTA TCCCCCGCCACGCCCGCCTCTTCCGCCGCTCGCGCGCGCGCGCACGGCCGGCCACGGCGCGCCGGGGTTGGCTGCTACAGGGACCGCGGT GGCGGCGGCGGCCTCGACAGCGGTAGTGCCTTCTACTCCGCTTTTTTAGTTTCCTCCGCCCCCTCCCGTGGGACGCTGTTGTGTGGCTGC CTTAAAAAAAAACGCAACTTTATTGTTCCTCAGCCCCACCTCCGGCTCGGCGGGCGTCCTCAGGATGCACTGAGGCTGAGGGGAGGGGAG GCGGCGGAGGGTCGAGGTCGCGGTCCCTCTCCTCCGAGCGCCCGGCTGGAGGGGAGGGAGTCACGATGTCTGGTAGCCGCCAGGCCGGGT CGGGCTCCGCTGGGACAAGCCCCGGGTCCTCGGCGGCCTCCTCGGTGACTTCCGCCTCCTCGTCTTTATCCTCTTCCCCGTCGCCGCCTT CCGTGGCGGTTTCGGCGGCAGCGCTGGTGTCCGGCGGGGTGGCCCAGGCCGCCGGCTCGGGCGGCCTCGGGGGCCCGGTGCGGCCTGTGT TGGTGGCGCCCGCCGTATCGGGTAGCGGCGGCGGGGCGGTGTCCACGGGCCTGTCCCGGCACAGCTGCGCGGCCAGGCCCAGCGCCGGCG TAGGAGGCAGCAGCTCCAGCCTAGGCAGCGGCAGCAGGAAGCGACCTCTCCTCGCCCCCCTCTGCAACGGGCTCATCAACTCCTACGAGG ACAAAAGCAACGACTTCGTATGCCCCATCTGCTTTGATATGATTGAAGAAGCATACATGACAAAATGTGGCCACAGCTTTTGCTACAAGT GTATTCATCAGAGTTTGGAGGACAATAATAGATGTCCCAAGTGTAACTATGTTGTGGACAATATTGACCATCTGTATCCTAATTTCTTGG TGAATGAACTCATTCTTAAACAGAAGCAAAGATTTGAGGAAAAGAGGTTCAAATTGGACCACTCAGTGAGTAGCACCAATGGCCACAGGT GGCAGATATTTCAAGATTGGTTGGGAACTGACCAAGATAACCTTGATTTGGCCAATGTCAATCTTATGTTGGAGTTACTAGTGCAGAAGA AGAAACAACTGGAAGCAGAATCACATGCAGCCCAACTACAGATTCTTATGGAATTCCTCAAGGTTGCAAGAAGAAATAAGAGAGAGCAAC TGGAACAGATCCAGAAGGAGCTAAGTGTTTTGGAAGAGGATATTAAGAGAGTGGAAGAAATGAGTGGCTTATACTCTCCTGTCAGTGAGG ATAGCACAGTGCCTCAATTTGAAGCTCCTTCTCCATCACACAGTAGTATTATTGATTCCACAGAATACAGCCAACCTCCAGGTTTCAGTG GCAGTTCTCAGACAAAGAAACAGCCTTGGTATAATAGCACGTTAGCATCAAGACGAAAACGACTTACTGCTCATTTTGAAGACTTGGAGC AGTGTTACTTTTCTACAAGGATGTCTCGTATCTCAGATGACAGTCGAACTGCAAGCCAGTTGGATGAATTTCAGGAATGCTTGTCCAAGT TTACTCGATATAATTCAGTACGACCTTTAGCCACATTGTCATATGCTAGTGATCTCTATAATGGTTCCAGTATAGTCTCTAGTATTGAAT TTGACCGGGATTGTGACTATTTTGCGATTGCTGGAGTTACAAAGAAGATTAAAGTCTATGAATATGACACTGTCATCCAGGATGCAGTGG ATATTCATTACCCTGAGAATGAAATGACCTGCAATTCGAAAATCAGCTGTATCAGTTGGAGTAGTTACCATAAGAACCTGTTAGCTAGCA GTGATTATGAAGGCACTGTTATTTTATGGGATGGATTCACAGGACAGAGGTCAAAGGTCTATCAGGAGCATGAGAAGAGGTGTTGGAGTG TTGACTTTAATTTGATGGATCCTAAACTCTTGGCTTCAGGTTCTGATGATGCAAAAGTGAAGCTGTGGTCTACCAATCTAGACAACTCAG TGGCAAGCATTGAGGCAAAGGCTAATGTGTGCTGTGTTAAATTCAGCCCCTCTTCCAGATACCATTTGGCTTTCGGCTGTGCAGCTATAT GCCGCTATCCTCTGGGCATGTCAGGAGGCCAGATTCCAGATGAGGACATCACAGCTTCCAGTCAGTGGTCAGAGTCCACAGCTGCCAAAT ATGGAAGGCTGGACTCAGAAGAAGGGGATGGAGCCTGGTGCCCTGAGATTCCAGTGGAACCTGATGACCTGAAGGAGTTTCTGCAGATTG ACTTGCACACCCTCCATTTTATCACTCTGGTGGGGACCCAGGGGCGCCATGCAGGAGGTCATGGCATCGAGTTTGCCCCCATGTACAAGA TCAATTACAGTCGGGATGGCACTCGCTGGATCTCTTGGCGGAACCGTCATGGGAAACAGGTGCTGGATGGAAATAGTAACCCCTATGACA TTTTCCTAAAGGACTTGGAGCCGCCCATTGTAGCCAGATTTGTCCGGTTCATTCCAGTCACCGACCACTCCATGAATGTGTGTATGAGAG TGGAGCTTTACGGCTGTGTCTGGCTAGATGGCTTGGTGTCTTACAATGCTCCAGCTGGGCAGCAGTTTGTACTCCCTGGAGGTTCCATCA TTTATCTGAATGATTCTGTCTATGATGGAGCTGTTGGATACAGCATGACAGAAGGGCTAGGCCAATTGACCGATGGTGTGTCTGGCCTGG ACGATTTCACCCAGACCCATGAATACCACGTGTGGCCCGGCTATGACTATGTGGGCTGGCGGAACGAGAGTGCCACCAATGGCTACATTG AGATCATGTTTGAATTTGACCGCATCAGGAATTTCACTACCATGAAGGTCCACTGCAACAACATGTTTGCTAAAGGTGTGAAGATCTTTA AGGAGGTACAGTGCTACTTCCGCTCTGAAGCCAGTGAGTGGGAACCTAATGCCATTTCCTTCCCCCTTGTCCTGGATGACGTCAACCCCA GTGCTCGGTTTGTCACGGTGCCTCTCCACCACCGAATGGCCAGTGCCATCAAGTGTCAATACCATTTTGCAGATACCTGGATGATGTTCA GTGAGATCACCTTCCAATCAGATGCTGCAATGTACAACAACTCTGAAGCCCTGCCCACCTCTCCTATGGCACCCACAACCTATGATCCAA TGCTTAAAGTTGATGACAGCAACACTCGGATCCTGATTGGCTGCTTGGTGGCCATCATCTTTATCCTCCTGGCCATCATTGTCATCATCC TCTGGAGGCAGTTCTGGCAGAAAATGCTGGAGAAGGCTTCTCGGAGGATGCTGGATGATGAAATGACAGTCAGCCTTTCCCTGCCAAGTG ATTCTAGCATGTTCAACAATAACCGCTCCTCATCACCTAGTGAACAAGGGTCCAACTCGACTTACGATCGCATCTTTCCCCTTCGCCCTG ACTACCAGGAGCCATCCAGGCTGATACGAAAACTCCCAGAATTTGCTCCAGGGGAGGAGGAGTCAGGCTGCAGCGGTGTTGTGAAGCCAG TCCAGCCCAGTGGCCCTGAGGGGGTGCCCCACTATGCAGAGGCTGACATAGTGAACCTCCAAGGAGTGACAGGAGGCAACACATACTCAG TGCCTGCCGTCACCATGGACCTGCTCTCAGGAAAAGATGTGGCTGTGGAGGAGTTCCCCAGGAAACTCCTAACTTTCAAAGAGAAGCTGG GAGAAGGACAGTTTGGGGAGGTTCATCTCTGTGAAGTGGAGGGAATGGAAAAATTCAAAGACAAAGATTTTGCCCTAGATGTCAGTGCCA ACCAGCCTGTCCTGGTGGCTGTGAAAATGCTCCGAGCAGATGCCAACAAGAATGCCAGGAATGATTTTCTTAAGGAGATAAAGATCATGT CTCGGCTCAAGGACCCAAACATCATCCATCTATTAGCTGTGTGTATCACTGATGACCCTCTCTGTATGATCACTGAATACATGGAGAATG GAGATCTCAATCAGTTTCTTTCCCGCCACGAGCCCCCTAATTCTTCCTCCAGCGATGTACGCACTGTCAGTTACACCAATCTGAAGTTTA TGGCTACCCAAATTGCCTCTGGCATGAAGTACCTTTCCTCTCTTAATTTTGTTCACCGAGATCTGGCCACACGAAACTGTTTAGTGGGTA AGAACTACACAATCAAGATAGCTGACTTTGGAATGAGCAGGAACCTGTACAGTGGTGACTATTACCGGATCCAGGGCCGGGCAGTGCTCC CTATCCGCTGGATGTCTTGGGAGAGTATCTTGCTGGGCAAGTTCACTACAGCAAGTGATGTGTGGGCCTTTGGGGTTACTTTGTGGGAGA CTTTCACCTTTTGTCAAGAACAGCCCTATTCCCAGCTGTCAGATGAACAGGTTATTGAGAATACTGGAGAGTTCTTCCGAGACCAAGGGA GGCAGACTTACCTCCCTCAACCAGCCATTTGTCCTGACTCTGTGTATAAGCTGATGCTCAGCTGCTGGAGAAGAGATACGAAGAACCGTC CCTCATTCCAAGAAATCCACCTTCTGCTCCTTCAACAAGGCGACGAGTGATGCTGTCAGTGCCTGGCCATGTTCCTACGGCTCAGGTCCT CCCTACAAGACCTACCACTCACCCATGCCTATGCCACTCCATCTGGACATTTAATGAAACTGAGAGACAGAGGCTTGTTTGCTTTGCCCT >In-frame_RFWD2_ENST00000308769_chr1_175996708_-_DDR2_ENST00000367922_chr1_162722885_+_11297nt ATGTCTGGTAGCCGCCAGGCCGGGTCGGGCTCCGCTGGGACAAGCCCCGGGTCCTCGGCGGCCTCCTCGGTGACTTCCGCCTCCTCGTCT TTATCCTCTTCCCCGTCGCCGCCTTCCGTGGCGGTTTCGGCGGCAGCGCTGGTGTCCGGCGGGGTGGCCCAGGCCGCCGGCTCGGGCGGC CTCGGGGGCCCGGTGCGGCCTGTGTTGGTGGCGCCCGCCGTATCGGGTAGCGGCGGCGGGGCGGTGTCCACGGGCCTGTCCCGGCACAGC TGCGCGGCCAGGCCCAGCGCCGGCGTAGGAGGCAGCAGCTCCAGCCTAGGCAGCGGCAGCAGGAAGCGACCTCTCCTCGCCCCCCTCTGC AACGGGCTCATCAACTCCTACGAGGACAAAAGCAACGACTTCGTATGCCCCATCTGCTTTGATATGATTGAAGAAGCATACATGACAAAA TGTGGCCACAGCTTTTGCTACAAGTGTATTCATCAGAGTTTGGAGGACAATAATAGATGTCCCAAGTGTAACTATGTTGTGGACAATATT GACCATCTGTATCCTAATTTCTTGGTGAATGAACTCATTCTTAAACAGAAGCAAAGATTTGAGGAAAAGAGGTTCAAATTGGACCACTCA AATGGCCACAGGTGGCAGATATTTCAAGATTGGTTGGGAACTGACCAAGATAACCTTGATTTGGCCAATGTCAATCTTATGTTGGAGTTA CTAGTGCAGAAGAAGAAACAACTGGAAGCAGAATCACATGCAGCCCAACTACAGATTCTTATGGAATTCCTCAAGGTTGCAAGAAGAAAT AAGAGAGAGGAAATGAGTGGCTTATACTCTCCTGTCAGTGAGGATAGCACAGTGCCTCAATTTGAAGCTCCTTCTCCATCACACAGTAGT ATTATTGATTCCACAGAATACAGCCAACCTCCAGGTTTCAGTGGCAGTTCTCAGACAAAGAAACAGCCTTGGTATAATAGCACGTTAGCA TCAAGACGAAAACGACTTACTGCTCATTTTGAAGACTTGGAGCAGTGTTACTTTTCTACAAGGATGTCTCGTATCTCAGATGACAGTCGA ACTGCAAGCCAGTTGGATGAATTTCAGGAATGCTTGTCCAAGTTTACTCGATATAATTCAGTACGACCTTTAGCCACATTGTCATATGCT AGTGATCTCTATAATGGTTCCAGTATAGTCTCTAGTATTGAATTTGACCGGGATTGTGACTATTTTGCGATTGCTGGAGTTACAAAGAAG ATTAAAGTCTATGAATATGACACTGTCATCCAGGATGCAGTGGATATTCATTACCCTGAGAATGAAATGACCTGCAATTCGAAAATCAGC TGTATCAGTTGGAGTAGTTACCATAAGAACCTGTTAGCTAGCAGTGATTATGAAGGCACTGTTATTTTATGGGATGGATTCACAGGACAG AGGTCAAAGGTCTATCAGGAGCATGAGAAGAGGTGTTGGAGTGTTGACTTTAATTTGATGGATCCTAAACTCTTGGCTTCAGGTTCTGAT GATGCAAAAGTGAAGCTGTGGTCTACCAATCTAGACAACTCAGTGGCAAGCATTGAGGCAAAGGCTAATGTGTGCTGTGTTAAATTCAGC CCCTCTTCCAGATACCATTTGGCTTTCGGCTGTGCAGCTATATGCCGCTATCCTCTGGGCATGTCAGGAGGCCAGATTCCAGATGAGGAC ATCACAGCTTCCAGTCAGTGGTCAGAGTCCACAGCTGCCAAATATGGAAGGCTGGACTCAGAAGAAGGGGATGGAGCCTGGTGCCCTGAG ATTCCAGTGGAACCTGATGACCTGAAGGAGTTTCTGCAGATTGACTTGCACACCCTCCATTTTATCACTCTGGTGGGGACCCAGGGGCGC CATGCAGGAGGTCATGGCATCGAGTTTGCCCCCATGTACAAGATCAATTACAGTCGGGATGGCACTCGCTGGATCTCTTGGCGGAACCGT CATGGGAAACAGGTGCTGGATGGAAATAGTAACCCCTATGACATTTTCCTAAAGGACTTGGAGCCGCCCATTGTAGCCAGATTTGTCCGG TTCATTCCAGTCACCGACCACTCCATGAATGTGTGTATGAGAGTGGAGCTTTACGGCTGTGTCTGGCTAGATGGCTTGGTGTCTTACAAT GCTCCAGCTGGGCAGCAGTTTGTACTCCCTGGAGGTTCCATCATTTATCTGAATGATTCTGTCTATGATGGAGCTGTTGGATACAGCATG ACAGAAGGGCTAGGCCAATTGACCGATGGTGTGTCTGGCCTGGACGATTTCACCCAGACCCATGAATACCACGTGTGGCCCGGCTATGAC TATGTGGGCTGGCGGAACGAGAGTGCCACCAATGGCTACATTGAGATCATGTTTGAATTTGACCGCATCAGGAATTTCACTACCATGAAG GTCCACTGCAACAACATGTTTGCTAAAGGTGTGAAGATCTTTAAGGAGGTACAGTGCTACTTCCGCTCTGAAGCCAGTGAGTGGGAACCT AATGCCATTTCCTTCCCCCTTGTCCTGGATGACGTCAACCCCAGTGCTCGGTTTGTCACGGTGCCTCTCCACCACCGAATGGCCAGTGCC ATCAAGTGTCAATACCATTTTGCAGATACCTGGATGATGTTCAGTGAGATCACCTTCCAATCAGATGCTGCAATGTACAACAACTCTGAA GCCCTGCCCACCTCTCCTATGGCACCCACAACCTATGATCCAATGCTTAAAGTTGATGACAGCAACACTCGGATCCTGATTGGCTGCTTG GTGGCCATCATCTTTATCCTCCTGGCCATCATTGTCATCATCCTCTGGAGGCAGTTCTGGCAGAAAATGCTGGAGAAGGCTTCTCGGAGG ATGCTGGATGATGAAATGACAGTCAGCCTTTCCCTGCCAAGTGATTCTAGCATGTTCAACAATAACCGCTCCTCATCACCTAGTGAACAA GGGTCCAACTCGACTTACGATCGCATCTTTCCCCTTCGCCCTGACTACCAGGAGCCATCCAGGCTGATACGAAAACTCCCAGAATTTGCT CCAGGGGAGGAGGAGTCAGGCTGCAGCGGTGTTGTGAAGCCAGTCCAGCCCAGTGGCCCTGAGGGGGTGCCCCACTATGCAGAGGCTGAC ATAGTGAACCTCCAAGGAGTGACAGGAGGCAACACATACTCAGTGCCTGCCGTCACCATGGACCTGCTCTCAGGAAAAGATGTGGCTGTG GAGGAGTTCCCCAGGAAACTCCTAACTTTCAAAGAGAAGCTGGGAGAAGGACAGTTTGGGGAGGTTCATCTCTGTGAAGTGGAGGGAATG GAAAAATTCAAAGACAAAGATTTTGCCCTAGATGTCAGTGCCAACCAGCCTGTCCTGGTGGCTGTGAAAATGCTCCGAGCAGATGCCAAC AAGAATGCCAGGAATGATTTTCTTAAGGAGATAAAGATCATGTCTCGGCTCAAGGACCCAAACATCATCCATCTATTAGCTGTGTGTATC ACTGATGACCCTCTCTGTATGATCACTGAATACATGGAGAATGGAGATCTCAATCAGTTTCTTTCCCGCCACGAGCCCCCTAATTCTTCC TCCAGCGATGTACGCACTGTCAGTTACACCAATCTGAAGTTTATGGCTACCCAAATTGCCTCTGGCATGAAGTACCTTTCCTCTCTTAAT TTTGTTCACCGAGATCTGGCCACACGAAACTGTTTAGTGGGTAAGAACTACACAATCAAGATAGCTGACTTTGGAATGAGCAGGAACCTG TACAGTGGTGACTATTACCGGATCCAGGGCCGGGCAGTGCTCCCTATCCGCTGGATGTCTTGGGAGAGTATCTTGCTGGGCAAGTTCACT ACAGCAAGTGATGTGTGGGCCTTTGGGGTTACTTTGTGGGAGACTTTCACCTTTTGTCAAGAACAGCCCTATTCCCAGCTGTCAGATGAA CAGGTTATTGAGAATACTGGAGAGTTCTTCCGAGACCAAGGGAGGCAGACTTACCTCCCTCAACCAGCCATTTGTCCTGACTCTGTGTAT AAGCTGATGCTCAGCTGCTGGAGAAGAGATACGAAGAACCGTCCCTCATTCCAAGAAATCCACCTTCTGCTCCTTCAACAAGGCGACGAG TGATGCTGTCAGTGCCTGGCCATGTTCCTACGGCTCAGGTCCTCCCTACAAGACCTACCACTCACCCATGCCTATGCCACTCCATCTGGA CATTTAATGAAACTGAGAGACAGAGGCTTGTTTGCTTTGCCCTCTTTTCCTGGTCACCCCCACTCCCTACCCCTGACTCATATACACTTT TTTTTTTTTTTACATTAAAGAACTAAAAAAGGAAAAAAAAAAGCCTAGGGCAGATACAATCTAGTAAAAGAAAATCTTTGATATACCAAA GTGTTGGATAACAAAGGCTAGAAAATTCAGATAATTTATAAAGGTTAACTATACTTGTGCTTATAAATGTGCAGATTCTACAATATTTTT CCATGTCATTCTAAAAGAATCTTCAGAAAGAAAAACTTGAAGAATACTAATGTCTTGGGAAACATGAGATTAAGTTTAGGGAAAACACTT GATAGATGTGGAGAATCTGAGGACTCAGAATTCAGCAACTAATCACAGGTGGTTTTCTAATTTGGCCTCTGGACATGTCTCACTGTTTGT ATTTCTCTCTCCTGTCAAAGTGAATGATATATTCTTGAAAACCCCCAATTTCTTGAAATGGGTGTTCTGTTCATTCATGGGCAGGGGTCA GGATTGAAGTTCATATATGAAACAACTGGGGATGTAGATAGGAAAGAATGTCTGCTGCAAGAGTGTATGAAGGGGGATTGTCATTTACAA AAAAAAAGTACCTCATGGATGGAAGGATTCATGAATAGATAATGGACATAGGAAAGGAGGTCAATGGAGGACACATAACAGACATGCTAT CCACCATTTATTTGTGATTTTGTAAGAGGGTTCTCTTCTTTGTCTTGTTCAGATATTTTCATGTGTGTGTTTTAGTGAGAATCTGAGTTT TTAATCAGTAAAGTCTGATGTTTTGATATCTTGATGTTTTGATGGTAGACTCTTGAGTTCATCTTGTCCAAATCTTCTAGCATTTTCAAG GATGAAGCCTCTGTGGGATCTTTGGGCTTGGGGCTGAATTTCTCAGGCATAAATACCTAATGGCCTTGTCTAAGAGGGAATAGATCTGTT CTGAGTGTCCCCAAAAAAGTTGTCCTAGGAACTGATGTGGAGAAGTTACAGGGAGACTGATTTCCATTCCTTATTGGGGAAAACGAAGCA CTCAGAACATACAAGGATAAATGGGCTGCCACCAGAGGTGAGGAGTCTCTTGTCACTGGAGAGGTTAAGATAGAGGCTCAAGAACAATGC AAGGAAAATGGAGGTTTTCAAACACAAAGTGGATGGTGGTATGAGACAATGTTTAATGTCCTTCTAACTCCGAGAGTCCTTGATTCTGGA GAGGCACAGGATGAACATCTGTTGCTACTGCTGAGTATACACACTCTTGCCTCTGAGATGGCGTGACCAGCAGAAAAGAAAGCTCAGGGC TGTGGCTTCAGAATTCATGGAAACAGAGCCACTGTCAAGAAGGAATCTGCTCAGAGCAGATTCTGAGTTTTCACACTCCACAAATCCTCA GATTTAGTGGGAAGCTGGAAAAAGGAACTCTTAATTCCAATTGAGGAGAAACAAGAAAACATTACAAATCAGTTTCCCAAGCTGAGAAGG ATTAGCCTTGACCCCTTGGGTCTGCCTCTGTTGCCCTCACCAGTTTACCTTCTACAACAGTTTCTCAGGAACATGTGTATTTCCCCATTC AGCTTTCAGCATTGCTCCACGCCACAGCATAAGCATAGATCCCAAGTCCACAGGCTCCATTTTGCAGGTCATCTTCTGATCCTAGCAAAT GTCCTTTCCCCATAGTTGTCCTATGCCTTTGGGCTTTAGTCTATCCCAGGACTAACTGTGGAGAAATCATTGGTTTGAGAGTCAAGAGAG CATTGGTTTGGGAGCTTTAATCCTCTTTCTGCTTCACACTAAGTGTGTCATCTTGGCTAAATCACTTGGTCTTTCTGCATTTTGTTTTCT TATTTATAGGATGAGGAAATTAGATTAAATGGTTTTGAGGTCCTTTCTTGTTCTGATATGTCCAGTACTCACTGGAAAATTGGATCTATA ACTGATGGGTTTAGTAATCTGGTCATTTCTTGCTCTGAAAATTGTAGTCAGCAAAAGAGATCATGGAAGAAATCACTGTAATGGTAGTAA TAGTAACACATGCCATTTGTATTGTGCCTTAGGTTTACCAGGTGTTTCCAAATACATTAGCATATTTGATATGTGCAGGACTAGATACCT TGGGACCTGCCACACTCCACTTTCAAGATATGTATTAGCTTCATTAGAATTAAAGGGACTTGAACTCAGGACCTGCAGCCTATTCTTCTT TATCCACATGTCTCTGGTAGGGCTACATCCAGATCACACCATGACTTCTTATAGAGCAAGAGAAAATAATATTATTATATCTTCCTTTGC CTAAAATCTCTCCACTTATTCTTTTTTATGATTCTGCACCAGTTCACTGGGTTATTCTATGATTCCATATTTTTTTTAAAAAAAATCATA TTTAAAATGAACTTACAATGTCTGAATTTTCCTGGCCTTGAGTCACAGAAGTAATATGTTTCAGATGGCTGCCCAATATGTATTATCATG TAATACATATCTGTGTCCTTTTCTGGGATGAGGAAGGCTTCAACTTCTGGCACTGAGAACTTTGTATTACAGACACAGGTTTAGTTTCTA GCTTAGTCATGCCTTTAGAGTTTAGTAGCACAAATCCATGCAACCCAACAGAATACATGGTGAGGGCCTAGTATGTAGAATTTGAAAGTA GTTCAAATTTGAATTAGAAGAATGAAGCTAGGACTTATTTGGAAAAGGAGATAGAAAAAAAATGATCAGAAACTGTGGGGCCTTATTACC TTTGCAGTAAGTTATCTTCTTCATGATATATGTGAATTATTTTATGTGCAGATTGTGTTTTGGGATTGTCAGATCTAAACTTATATTCTT GCTGGCTAATGTGCTGATAGCCAGGTCTGAAACTTGATGTGCTATCCAGACACATATGATCAGAAAAGATCTAGAGTGCAAAGAGGTGCC TGAGGAGCAAAATGTGGTTTTAATGTTGTGGAAAGATCACTTGCAAGTATATAAGACTGTATAAAGAAGAGGACTGTGTGCAAGTGGGGT GAAAAAAAAGGATACGTGAATGTGCATATGACTGAATAGGGAGGAAGGTCAGGGCTAGAAAGGAGGCTACATAAAAAGGGGCAATGGAGA ATGCACAGGAAAGACACAGGGGAAGGTCAAGTCGAGCAAGGTAGAAACAGGAGTAGCTAGAGCCATTGGGAATCCATTTTGAAACAAGAA GGAGTTTTGAAAGGGAATAGGAAAGTAAGTGTCTTGAAGTAAAAGATAAATATGGATGGAGAAAGAAGAAATTCTGGATGATAGAGATGA TAAAAATATTTATTAAGAAATGAAGTCAGGTTCAGTGTATGAAATGGAAAGGAATTTTTCAGAATTTTAAGAAAGGGGAAGTTCCTCTTG GAAAAGATATAGCAACCATCGGGGAATGACCTTTTCATTTCAGAAGTGGATGAGGAAGGTGGTGTGAGCATCAGGTATATTCTGGACCAT TTCAAGTGCTGGTGAGAAGAAAGGAACTCTTTGCCTGAACTGGGCTTGGTTTTCCAAGTGCTGCTTTGGAAATGAAGACCCAGAGATGCA GAGCTTATGGTAGTTCATAAATCTTCATGTTCTATTATCTTTCATCTGCCAATAAAGTTCATTTTCAATAATGTCCACCATTGCTGTGCC CAGAATAACCACAGGCAAACATCAAAACAATACGCATAAGTTAGACAAGATTAAATCTTGTCTGATATCTGCACAAACAGATATGCACCA TGTTGGAAACATGTGTTTTCCTAGTCCCATCCAGGCTTCCCACAAGAAAGCCATGATGTGGGTCTAAACCATATGTTTTGAGTAAAGGAG AATAGAAGAAGGGGAGTGTCCGCAAAATGGAAAGAGATGAAGATGTTCCAAGGAAGTATGCTGAAACAGAACAGTGAATGTTTTGCCCAA AACTACAAAAATAAAAGAAAAAAAGAAAATTGCAATACATGGCTACTAAGTCTTTGATCATAAGTCGAATTTATAGACCTGGAATTTGCC ATCCTAGTCTTTCCTTTTTAGTAAGACTTCTGTCCTCTGGCAGTGCATATGGTAGGTCTCTAATGTTTCTTCATCTCCAGGAAGATGCAG ATCCTTATTTTTGCTGGGAAATCCTTCTAAATAGAAATGTAACATTTTTATAAAAACAGATTAATGTGTTTTTCACTTAGTAAATGTTTT CAAGAGCTGAATTGAGAAGGAAAGAGACTGGAGTGGTTAATGGTGATTTGATTTCTGGCATTCTGAGTTTTCTGCTACAATTAGCTGCAT TACTTGGTGCCAAAGAGCAGTGGGGAATTGTTGAGTTGCTGTATCCTTTAAAAAAAAACAAAAAACTTGTTATTTTGAAAGAACTTAAGG CTCACAAGATGTTACAAAAATAGTAGAGTGGCCTTACCCTAGATCCAGTTTTCCCCATTTATAACATTTCACTTAGTCCATTTTCGGAAC CAGAAAATTAACATTGGCATAATGCTATTAACTAAACTACAGACCTTTTTTCAATTTCGCCAGTTTTTCCACACATATTCATTTAGTTGC TGGATACTTTTAATTCTTGCTGATTTGTAAACTGGCCTTGCTTGGATACAACAGGAAAGATACTATCTGGATAAAGTTCTACAGTTTTAG AGAGACTATTAACACATTAATGTGTTCCTTTGTCATGAGCAATACCCTGCCTACACTGCTTCTAAATTTTCTGATTTGTTTGGCTGTTTG GCATCTGAAACAATCCAAGACAAACTTAGAAAGATTAGGCAACACAAAACACAGTAAGACCTGTTCATAGCTTGTTGTCTAGAAAACCAG GTAGCAGGATATTCTAGATGCTTCCTGCTGCTTCTACGTGAGTAGGATTAGCACTGGGGACAAAATAAGGAGTTTAGAGTAAACCAGTAT TTCAGTCAAGAGTTAGTTGGCACTTAGTTAATGGCACTGGAAATAGCTTGTGGAGAGAATAGAATACAATGGTATAGACTCCTAATGTTT GATAAAATACTATTTTCAGAGTGGTAGAGAGGTTTTATTTGCCTAAATAGCCGTTATTAAATGGAATAACAACCACATTAGACCAAATTA ATTGCAAACACAGCGGCAACCTGGGGAGAAGTTGAAACTCCAGTTTTGTGGATTACAGTTTTGAGTTTTATGATTGACATTTTTAAGTCC CCTATTTAAGGGGTCAAGATTATAACAATGTGTGTCTTACTAAGTTTCTAGGTCATTGTGAGCACTTGATAAATATTTGCTGAATGTTGT TTTTTTGAATGAACATAAGATAGAAACAAAAACTTCTCATCCAGTTAACTAGAGTGAATGTAGGGAGAATTGTTTTGCTTGTAACATGGA GAGTTTATTTTCAAGTGAGGAAAGAGAAAAAAATTACTCAGACTTGTTCCTGGTGAAGTGCATTCTCTGTTTGTATACTTTTTGATGGAG AAATTGATCTATAGAACTGCTTAATTTTTTGAGGCATTTAGACAGCAATGAAAGGTAGTTCTCCACAGGACACCGAATCAAAAGGAGAGA CCAGACTCTGGCCTCATACCCAGCCTATTTGAAACAAGCTATCTAGTTTCTCCTGCAGACACCTTGTCAACAACATGCAACAGTGTCAGG TGCCTTGCAGGAAAATAATCTGAGTCCCAAGCTAGCCTGTGCTCATCCACAATCACAATGAACATGTCAAGGAAGAATTTGCAGAGACTC AAGGGAAGCACAATGGGATAAGGTAATCACTTTCAGTGAAAAACTGTTTTCTTGAAAACAGGCTTGGACACAATTGAAAGCTGGCTTCCT GCAAACACACCAAGAGTCTGTAATCTAGCCTATCCATTATATGTCCTTTATTATTCATGATATCCTATTCTTCTACCTTGTTGCCTGGTA ACTTTTTCTGAGGACTGAGTTTCTGCAGCGATGTGGTGCACTCTTCCTGTGATGAGGAAACATCTGGGCCCCCTTCTGCAGGCTTTGGAA GATGATGTGTCTTGTCAAGGGGTAAAGGGCAAATGGATTTAATTTCTGCTTAAAACTATCATAGACGTTCCAAATAGAATATGTAAAATT TCTCTGTATTAGAAAAAGAAACGTGATACCAATTGTATATTTTCTTTTCTTTATTTATTCTCTGTAAGTCTGTCAGATGATAAATTGTAA ATAACAATGATTAAAGAGTCATGCTACTGATGGATCTCCCTTTCTGTATAAACAGTGCCAGTTCTGGGCTTTGTAACCTTTGCTCTTTAT AGTCTTTCATTCCTGGGGAAGTGATGGGGCATGGGCCCAGAGCTGGGGTGTATGTGGTATGGACACCTGTTTGTGGGGCTTTCCAGCAAA GGATTATTTAAATAGACCTCTAACATATGAGTTGACTGTTTATTGGGAAGAAAGCATCTTGGTCTCTGACATATCCAAACATACGAGACA CTGGGATTTTACGTCCTCACATTAATTAGTCCAGTTCTGGGGAATCCAGTCTAGAATTAACTGGTGATCCCTTATCGTTATGGTTACAGA CTTGTCTTGTTTGATACACAGAAATCCTTTTTAAATCCAAATATAGTCTGTCTCAGACTACCTGCACATGCACAAACCAAAAAAAACTAT GAAAACCAGAATTTAGACTCAGTCATTATACTAGAGATTAGAATGAAACGACCCCAAACAACCCATTTCTTACCTGGTCTCTGAGAATAA GTTTATACTTTTAGTTTTCTGAGAATATTTCTCAGAATATGTGAGTTTTCTGAGCACATTTTTCAGCATGGGGTATGGTAGATAAATCAC AGGGCCAAGGTTTGGCAGGGATAGATGGGATCATTGTGTACCCTATTGTTCTTCTGATTTCCAGGAGAACAGAATGAGCCCATGCAAAAC ATAAACTTATGATGATTAAAAAAAACACACCTATCCATTCACTCATCAATAAAAACATATTATGATGGTTATCAAGCTGTGTCCTATGAG >In-frame_RFWD2_ENST00000308769_chr1_175996708_-_DDR2_ENST00000367921_chr1_162722885_+_4318nt ATGTCTGGTAGCCGCCAGGCCGGGTCGGGCTCCGCTGGGACAAGCCCCGGGTCCTCGGCGGCCTCCTCGGTGACTTCCGCCTCCTCGTCT TTATCCTCTTCCCCGTCGCCGCCTTCCGTGGCGGTTTCGGCGGCAGCGCTGGTGTCCGGCGGGGTGGCCCAGGCCGCCGGCTCGGGCGGC CTCGGGGGCCCGGTGCGGCCTGTGTTGGTGGCGCCCGCCGTATCGGGTAGCGGCGGCGGGGCGGTGTCCACGGGCCTGTCCCGGCACAGC TGCGCGGCCAGGCCCAGCGCCGGCGTAGGAGGCAGCAGCTCCAGCCTAGGCAGCGGCAGCAGGAAGCGACCTCTCCTCGCCCCCCTCTGC AACGGGCTCATCAACTCCTACGAGGACAAAAGCAACGACTTCGTATGCCCCATCTGCTTTGATATGATTGAAGAAGCATACATGACAAAA TGTGGCCACAGCTTTTGCTACAAGTGTATTCATCAGAGTTTGGAGGACAATAATAGATGTCCCAAGTGTAACTATGTTGTGGACAATATT GACCATCTGTATCCTAATTTCTTGGTGAATGAACTCATTCTTAAACAGAAGCAAAGATTTGAGGAAAAGAGGTTCAAATTGGACCACTCA AATGGCCACAGGTGGCAGATATTTCAAGATTGGTTGGGAACTGACCAAGATAACCTTGATTTGGCCAATGTCAATCTTATGTTGGAGTTA CTAGTGCAGAAGAAGAAACAACTGGAAGCAGAATCACATGCAGCCCAACTACAGATTCTTATGGAATTCCTCAAGGTTGCAAGAAGAAAT AAGAGAGAGGAAATGAGTGGCTTATACTCTCCTGTCAGTGAGGATAGCACAGTGCCTCAATTTGAAGCTCCTTCTCCATCACACAGTAGT ATTATTGATTCCACAGAATACAGCCAACCTCCAGGTTTCAGTGGCAGTTCTCAGACAAAGAAACAGCCTTGGTATAATAGCACGTTAGCA TCAAGACGAAAACGACTTACTGCTCATTTTGAAGACTTGGAGCAGTGTTACTTTTCTACAAGGATGTCTCGTATCTCAGATGACAGTCGA ACTGCAAGCCAGTTGGATGAATTTCAGGAATGCTTGTCCAAGTTTACTCGATATAATTCAGTACGACCTTTAGCCACATTGTCATATGCT AGTGATCTCTATAATGGTTCCAGTATAGTCTCTAGTATTGAATTTGACCGGGATTGTGACTATTTTGCGATTGCTGGAGTTACAAAGAAG ATTAAAGTCTATGAATATGACACTGTCATCCAGGATGCAGTGGATATTCATTACCCTGAGAATGAAATGACCTGCAATTCGAAAATCAGC TGTATCAGTTGGAGTAGTTACCATAAGAACCTGTTAGCTAGCAGTGATTATGAAGGCACTGTTATTTTATGGGATGGATTCACAGGACAG AGGTCAAAGGTCTATCAGGAGCATGAGAAGAGGTGTTGGAGTGTTGACTTTAATTTGATGGATCCTAAACTCTTGGCTTCAGGTTCTGAT GATGCAAAAGTGAAGCTGTGGTCTACCAATCTAGACAACTCAGTGGCAAGCATTGAGGCAAAGGCTAATGTGTGCTGTGTTAAATTCAGC CCCTCTTCCAGATACCATTTGGCTTTCGGCTGTGCAGCTATATGCCGCTATCCTCTGGGCATGTCAGGAGGCCAGATTCCAGATGAGGAC ATCACAGCTTCCAGTCAGTGGTCAGAGTCCACAGCTGCCAAATATGGAAGGCTGGACTCAGAAGAAGGGGATGGAGCCTGGTGCCCTGAG ATTCCAGTGGAACCTGATGACCTGAAGGAGTTTCTGCAGATTGACTTGCACACCCTCCATTTTATCACTCTGGTGGGGACCCAGGGGCGC CATGCAGGAGGTCATGGCATCGAGTTTGCCCCCATGTACAAGATCAATTACAGTCGGGATGGCACTCGCTGGATCTCTTGGCGGAACCGT CATGGGAAACAGGTGCTGGATGGAAATAGTAACCCCTATGACATTTTCCTAAAGGACTTGGAGCCGCCCATTGTAGCCAGATTTGTCCGG TTCATTCCAGTCACCGACCACTCCATGAATGTGTGTATGAGAGTGGAGCTTTACGGCTGTGTCTGGCTAGATGGCTTGGTGTCTTACAAT GCTCCAGCTGGGCAGCAGTTTGTACTCCCTGGAGGTTCCATCATTTATCTGAATGATTCTGTCTATGATGGAGCTGTTGGATACAGCATG ACAGAAGGGCTAGGCCAATTGACCGATGGTGTGTCTGGCCTGGACGATTTCACCCAGACCCATGAATACCACGTGTGGCCCGGCTATGAC TATGTGGGCTGGCGGAACGAGAGTGCCACCAATGGCTACATTGAGATCATGTTTGAATTTGACCGCATCAGGAATTTCACTACCATGAAG GTCCACTGCAACAACATGTTTGCTAAAGGTGTGAAGATCTTTAAGGAGGTACAGTGCTACTTCCGCTCTGAAGCCAGTGAGTGGGAACCT AATGCCATTTCCTTCCCCCTTGTCCTGGATGACGTCAACCCCAGTGCTCGGTTTGTCACGGTGCCTCTCCACCACCGAATGGCCAGTGCC ATCAAGTGTCAATACCATTTTGCAGATACCTGGATGATGTTCAGTGAGATCACCTTCCAATCAGATGCTGCAATGTACAACAACTCTGAA GCCCTGCCCACCTCTCCTATGGCACCCACAACCTATGATCCAATGCTTAAAGTTGATGACAGCAACACTCGGATCCTGATTGGCTGCTTG GTGGCCATCATCTTTATCCTCCTGGCCATCATTGTCATCATCCTCTGGAGGCAGTTCTGGCAGAAAATGCTGGAGAAGGCTTCTCGGAGG ATGCTGGATGATGAAATGACAGTCAGCCTTTCCCTGCCAAGTGATTCTAGCATGTTCAACAATAACCGCTCCTCATCACCTAGTGAACAA GGGTCCAACTCGACTTACGATCGCATCTTTCCCCTTCGCCCTGACTACCAGGAGCCATCCAGGCTGATACGAAAACTCCCAGAATTTGCT CCAGGGGAGGAGGAGTCAGGCTGCAGCGGTGTTGTGAAGCCAGTCCAGCCCAGTGGCCCTGAGGGGGTGCCCCACTATGCAGAGGCTGAC ATAGTGAACCTCCAAGGAGTGACAGGAGGCAACACATACTCAGTGCCTGCCGTCACCATGGACCTGCTCTCAGGAAAAGATGTGGCTGTG GAGGAGTTCCCCAGGAAACTCCTAACTTTCAAAGAGAAGCTGGGAGAAGGACAGTTTGGGGAGGTTCATCTCTGTGAAGTGGAGGGAATG GAAAAATTCAAAGACAAAGATTTTGCCCTAGATGTCAGTGCCAACCAGCCTGTCCTGGTGGCTGTGAAAATGCTCCGAGCAGATGCCAAC AAGAATGCCAGGAATGATTTTCTTAAGGAGATAAAGATCATGTCTCGGCTCAAGGACCCAAACATCATCCATCTATTAGCTGTGTGTATC ACTGATGACCCTCTCTGTATGATCACTGAATACATGGAGAATGGAGATCTCAATCAGTTTCTTTCCCGCCACGAGCCCCCTAATTCTTCC TCCAGCGATGTACGCACTGTCAGTTACACCAATCTGAAGTTTATGGCTACCCAAATTGCCTCTGGCATGAAGTACCTTTCCTCTCTTAAT TTTGTTCACCGAGATCTGGCCACACGAAACTGTTTAGTGGGTAAGAACTACACAATCAAGATAGCTGACTTTGGAATGAGCAGGAACCTG TACAGTGGTGACTATTACCGGATCCAGGGCCGGGCAGTGCTCCCTATCCGCTGGATGTCTTGGGAGAGTATCTTGCTGGGCAAGTTCACT ACAGCAAGTGATGTGTGGGCCTTTGGGGTTACTTTGTGGGAGACTTTCACCTTTTGTCAAGAACAGCCCTATTCCCAGCTGTCAGATGAA CAGGTTATTGAGAATACTGGAGAGTTCTTCCGAGACCAAGGGAGGCAGACTTACCTCCCTCAACCAGCCATTTGTCCTGACTCTGTGTAT AAGCTGATGCTCAGCTGCTGGAGAAGAGATACGAAGAACCGTCCCTCATTCCAAGAAATCCACCTTCTGCTCCTTCAACAAGGCGACGAG TGATGCTGTCAGTGCCTGGCCATGTTCCTACGGCTCAGGTCCTCCCTACAAGACCTACCACTCACCCATGCCTATGCCACTCCATCTGGA |
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FusionGenePPI for RFWD2_DDR2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| RFWD2 | DET1, DDB1, CUL4A, RBX1, JUN, RFWD2, JUND, FOXO1, CRTC2, TP53, HSPA8, HSPA6, HSPA2, CCT3, TCP1, CCT6A, CCT5, CCT8, CCT7, CCT4, CCT2, CUL4B, WDR5, COPS2, COPS8, ETV5, ETV1, ETV4, MDM2, MDM4, RCHY1, YWHAZ, YWHAB, TRIB3, ELAVL1, MVP, CUL3, LRR1, DDA1, COPS3, COPS4, COPS5, COPS6, COPS7A, COPS7B, CUL1, SKP1, CUL2, TCEB2, BTBD2, KLHL42, DDB2, ERCC8, VPRBP, DCAF11, UBE2D2, PTPN11, REG1A, RB1CC1, SFN, UBE2D1, PTPN1, PARP4, TRIB1, JUNB, ETS2, ETS1, TRIB2, ZNF397, DMC1, FOSL2, FOS, STK40, CDKN1B, ATF6, STAT3, SEPSECS, SPOP, FAM120B, PPP2R2D, AGGF1, TAX1BP1, JPH1, TSKS, NFIL3, PPP2CA, CEP164, KHDRBS2, TINAG, CCT6B, ZNF263, PNPLA2, TRIM25 | DDR2 | SHC1, SRC, ELAVL1, HSP90AA1, CBLB, CDH1, CDH2, NTRK1, CHORDC1, GOLT1B |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | RFWD2 | chr1:175996708 | chr1:162722885 | ENST00000308769 | - | 14 | 19 | 643_645 | 552 | 708 | TRIB1 |
| Hgene | RFWD2 | chr1:175996708 | chr1:162722885 | ENST00000367669 | - | 15 | 20 | 643_645 | 576 | 732 | TRIB1 |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for RFWD2_DDR2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Tgene | DDR2 | Q16832 | DB08896 | Regorafenib | Discoidin domain-containing receptor 2 | small molecule | approved |
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RelatedDiseases for RFWD2_DDR2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | DDR2 | C1849011 | SPONDYLOMETAEPIPHYSEAL DYSPLASIA, SHORT LIMB-HAND TYPE | 2 | CTD_human;ORPHANET;UNIPROT |
| Tgene | DDR2 | C0152013 | Adenocarcinoma of lung (disorder) | 1 | CTD_human |
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