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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDrugs

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RelatedDiseases

Fusion gene ID: 30994

FusionGeneSummary for REV1_AFF3

check button Fusion gene summary
Fusion gene informationFusion gene name: REV1_AFF3
Fusion gene ID: 30994
HgeneTgene
Gene symbol

REV1

AFF3

Gene ID

51455

3899

Gene nameREV1, DNA directed polymeraseAF4/FMR2 family member 3
SynonymsAIBP80|REV1LLAF4|MLLT2-like
Cytomap

2q11.2

2q11.2

Type of geneprotein-codingprotein-coding
DescriptionDNA repair protein REV1REV1 homologREV1, polymerase (DNA directed)REV1- likealpha integrin-binding protein 80rev1-like terminal deoxycytidyl transferaseAF4/FMR2 family member 3MLLT2-related proteinlymphoid nuclear protein 4lymphoid nuclear protein related to AF4protein LAF-4
Modification date2018052220180523
UniProtAcc

Q9UBZ9

P51826

Ensembl transtripts involved in fusion geneENST00000393445, ENST00000258428, 
ENST00000465835, 
ENST00000409236, 
ENST00000356421, ENST00000317233, 
ENST00000409579, ENST00000483600, 
Fusion gene scores* DoF score8 X 7 X 4=2247 X 7 X 4=196
# samples 77
** MAII scorelog2(7/224*10)=-1.67807190511264
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(7/196*10)=-1.48542682717024
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: REV1 [Title/Abstract] AND AFF3 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationOncogene involved fusion gene, in-frame and retained their domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneREV1

GO:0009411

response to UV

11485998


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVPAADTCGA-HZ-8637-01AREV1chr2

100065798

-AFF3chr2

100185377

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000393445ENST00000409236REV1chr2

100065798

-AFF3chr2

100185377

-
In-frameENST00000393445ENST00000356421REV1chr2

100065798

-AFF3chr2

100185377

-
In-frameENST00000393445ENST00000317233REV1chr2

100065798

-AFF3chr2

100185377

-
In-frameENST00000393445ENST00000409579REV1chr2

100065798

-AFF3chr2

100185377

-
5CDS-intronENST00000393445ENST00000483600REV1chr2

100065798

-AFF3chr2

100185377

-
In-frameENST00000258428ENST00000409236REV1chr2

100065798

-AFF3chr2

100185377

-
In-frameENST00000258428ENST00000356421REV1chr2

100065798

-AFF3chr2

100185377

-
In-frameENST00000258428ENST00000317233REV1chr2

100065798

-AFF3chr2

100185377

-
In-frameENST00000258428ENST00000409579REV1chr2

100065798

-AFF3chr2

100185377

-
5CDS-intronENST00000258428ENST00000483600REV1chr2

100065798

-AFF3chr2

100185377

-
5UTR-3CDSENST00000465835ENST00000409236REV1chr2

100065798

-AFF3chr2

100185377

-
5UTR-3CDSENST00000465835ENST00000356421REV1chr2

100065798

-AFF3chr2

100185377

-
5UTR-3CDSENST00000465835ENST00000317233REV1chr2

100065798

-AFF3chr2

100185377

-
5UTR-3CDSENST00000465835ENST00000409579REV1chr2

100065798

-AFF3chr2

100185377

-
5UTR-intronENST00000465835ENST00000483600REV1chr2

100065798

-AFF3chr2

100185377

-

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FusionProtFeatures for REV1_AFF3


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
REV1

Q9UBZ9

AFF3

P51826

Deoxycytidyl transferase involved in DNA repair.Transfers a dCMP residue from dCTP to the 3'-end of a DNA primerin a template-dependent reaction. May assist in the first step inthe bypass of abasic lesions by the insertion of a nucleotideopposite the lesion. Required for normal induction of mutations byphysical and chemical agents. {ECO:0000269|PubMed:10536157,ECO:0000269|PubMed:10760286, ECO:0000269|PubMed:11278384,ECO:0000269|PubMed:11485998, ECO:0000269|PubMed:22266823}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneREV1chr2:100065798chr2:100185377ENST00000258428-423419_6531161252DomainUmuC
HgeneREV1chr2:100065798chr2:100185377ENST00000258428-42344_1311161252DomainBRCT
HgeneREV1chr2:100065798chr2:100185377ENST00000393445-423419_6531161251DomainUmuC
HgeneREV1chr2:100065798chr2:100185377ENST00000393445-42344_1311161251DomainBRCT
HgeneREV1chr2:100065798chr2:100185377ENST00000258428-4231071_10781161252MotifNuclear localization signal
HgeneREV1chr2:100065798chr2:100185377ENST00000393445-4231071_10781161251MotifNuclear localization signal
HgeneREV1chr2:100065798chr2:100185377ENST00000258428-423423_4271161252Nucleotide bindingdCTP binding
HgeneREV1chr2:100065798chr2:100185377ENST00000258428-423510_5161161252Nucleotide bindingdCTP binding
HgeneREV1chr2:100065798chr2:100185377ENST00000393445-423423_4271161251Nucleotide bindingdCTP binding
HgeneREV1chr2:100065798chr2:100185377ENST00000393445-423510_5161161251Nucleotide bindingdCTP binding
TgeneAFF3chr2:100065798chr2:100185377ENST00000317233-1624413_4199721227Compositional biasNote=Poly-Ser
TgeneAFF3chr2:100065798chr2:100185377ENST00000317233-1624422_4329721227Compositional biasNote=Poly-Ser
TgeneAFF3chr2:100065798chr2:100185377ENST00000317233-1624440_4459721227Compositional biasNote=Poly-Ser
TgeneAFF3chr2:100065798chr2:100185377ENST00000317233-1624670_6799721227Compositional biasNote=Poly-Ser
TgeneAFF3chr2:100065798chr2:100185377ENST00000356421-1624413_4199971252Compositional biasNote=Poly-Ser
TgeneAFF3chr2:100065798chr2:100185377ENST00000356421-1624422_4329971252Compositional biasNote=Poly-Ser
TgeneAFF3chr2:100065798chr2:100185377ENST00000356421-1624440_4459971252Compositional biasNote=Poly-Ser
TgeneAFF3chr2:100065798chr2:100185377ENST00000356421-1624670_6799971252Compositional biasNote=Poly-Ser
TgeneAFF3chr2:100065798chr2:100185377ENST00000409236-1523413_4199721227Compositional biasNote=Poly-Ser
TgeneAFF3chr2:100065798chr2:100185377ENST00000409236-1523422_4329721227Compositional biasNote=Poly-Ser
TgeneAFF3chr2:100065798chr2:100185377ENST00000409236-1523440_4459721227Compositional biasNote=Poly-Ser
TgeneAFF3chr2:100065798chr2:100185377ENST00000409236-1523670_6799721227Compositional biasNote=Poly-Ser
TgeneAFF3chr2:100065798chr2:100185377ENST00000409579-1725413_4199971252Compositional biasNote=Poly-Ser
TgeneAFF3chr2:100065798chr2:100185377ENST00000409579-1725422_4329971252Compositional biasNote=Poly-Ser
TgeneAFF3chr2:100065798chr2:100185377ENST00000409579-1725440_4459971252Compositional biasNote=Poly-Ser
TgeneAFF3chr2:100065798chr2:100185377ENST00000409579-1725670_6799971252Compositional biasNote=Poly-Ser


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FusionGeneSequence for REV1_AFF3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_REV1_ENST00000393445_chr2_100065798_-_AFF3_ENST00000409236_chr2_100185377_-_371aa
MRRGGWRKRAENDGWETWGGTMAAKVQKLEEQFRSDAAMQKDGTSSTIFSGVAITVNGYTDPSAEELRKLMMLHGGQYHVTTSRSKTTHI
IATNLPNAKIKELKGEKVIRPEWIVERPRSADTFMQEAKRMKHKADAMVEKFGKALNTAEAALSFIECGNAMEQGPMESKSPTTMTSETV
ELIRTAMRLKTHSGPNATPEDKQLAALCYRCLALLYWRMFRLKRDHAVKTSKALIDTFKNSSKAAQAPSPWGASGKSTGTPSPMSPNPSP
ASSVGSQGSLSNASALSPSTIVSIPQRIHQMAANHVSITNSILHSYDYWEMADNLAKENREFFNDLDLLMGPVTLHSSMEHLVQYSQQGL

>In-frame_REV1_ENST00000393445_chr2_100065798_-_AFF3_ENST00000356421_chr2_100185377_-_371aa
MRRGGWRKRAENDGWETWGGTMAAKVQKLEEQFRSDAAMQKDGTSSTIFSGVAITVNGYTDPSAEELRKLMMLHGGQYHVTTSRSKTTHI
IATNLPNAKIKELKGEKVIRPEWIVERPRSADTFMQEAKRMKHKADAMVEKFGKALNTAEAALSFIECGNAMEQGPMESKSPTTMTSETV
ELIRTAMRLKTHSGPNATPEDKQLAALCYRCLALLYWRMFRLKRDHAVKTSKALIDTFKNSSKAAQAPSPWGASGKSTGTPSPMSPNPSP
ASSVGSQGSLSNASALSPSTIVSIPQRIHQMAANHVSITNSILHSYDYWEMADNLAKENREFFNDLDLLMGPVTLHSSMEHLVQYSQQGL

>In-frame_REV1_ENST00000393445_chr2_100065798_-_AFF3_ENST00000317233_chr2_100185377_-_371aa
MRRGGWRKRAENDGWETWGGTMAAKVQKLEEQFRSDAAMQKDGTSSTIFSGVAITVNGYTDPSAEELRKLMMLHGGQYHVTTSRSKTTHI
IATNLPNAKIKELKGEKVIRPEWIVERPRSADTFMQEAKRMKHKADAMVEKFGKALNTAEAALSFIECGNAMEQGPMESKSPTTMTSETV
ELIRTAMRLKTHSGPNATPEDKQLAALCYRCLALLYWRMFRLKRDHAVKTSKALIDTFKNSSKAAQAPSPWGASGKSTGTPSPMSPNPSP
ASSVGSQGSLSNASALSPSTIVSIPQRIHQMAANHVSITNSILHSYDYWEMADNLAKENREFFNDLDLLMGPVTLHSSMEHLVQYSQQGL

>In-frame_REV1_ENST00000393445_chr2_100065798_-_AFF3_ENST00000409579_chr2_100185377_-_371aa
MRRGGWRKRAENDGWETWGGTMAAKVQKLEEQFRSDAAMQKDGTSSTIFSGVAITVNGYTDPSAEELRKLMMLHGGQYHVTTSRSKTTHI
IATNLPNAKIKELKGEKVIRPEWIVERPRSADTFMQEAKRMKHKADAMVEKFGKALNTAEAALSFIECGNAMEQGPMESKSPTTMTSETV
ELIRTAMRLKTHSGPNATPEDKQLAALCYRCLALLYWRMFRLKRDHAVKTSKALIDTFKNSSKAAQAPSPWGASGKSTGTPSPMSPNPSP
ASSVGSQGSLSNASALSPSTIVSIPQRIHQMAANHVSITNSILHSYDYWEMADNLAKENREFFNDLDLLMGPVTLHSSMEHLVQYSQQGL

>In-frame_REV1_ENST00000258428_chr2_100065798_-_AFF3_ENST00000409236_chr2_100185377_-_371aa
MRRGGWRKRAENDGWETWGGTMAAKVQKLEEQFRSDAAMQKDGTSSTIFSGVAITVNGYTDPSAEELRKLMMLHGGQYHVTTSRSKTTHI
IATNLPNAKIKELKGEKVIRPEWIVERPRSADTFMQEAKRMKHKADAMVEKFGKALNTAEAALSFIECGNAMEQGPMESKSPTTMTSETV
ELIRTAMRLKTHSGPNATPEDKQLAALCYRCLALLYWRMFRLKRDHAVKTSKALIDTFKNSSKAAQAPSPWGASGKSTGTPSPMSPNPSP
ASSVGSQGSLSNASALSPSTIVSIPQRIHQMAANHVSITNSILHSYDYWEMADNLAKENREFFNDLDLLMGPVTLHSSMEHLVQYSQQGL

>In-frame_REV1_ENST00000258428_chr2_100065798_-_AFF3_ENST00000356421_chr2_100185377_-_371aa
MRRGGWRKRAENDGWETWGGTMAAKVQKLEEQFRSDAAMQKDGTSSTIFSGVAITVNGYTDPSAEELRKLMMLHGGQYHVTTSRSKTTHI
IATNLPNAKIKELKGEKVIRPEWIVERPRSADTFMQEAKRMKHKADAMVEKFGKALNTAEAALSFIECGNAMEQGPMESKSPTTMTSETV
ELIRTAMRLKTHSGPNATPEDKQLAALCYRCLALLYWRMFRLKRDHAVKTSKALIDTFKNSSKAAQAPSPWGASGKSTGTPSPMSPNPSP
ASSVGSQGSLSNASALSPSTIVSIPQRIHQMAANHVSITNSILHSYDYWEMADNLAKENREFFNDLDLLMGPVTLHSSMEHLVQYSQQGL

>In-frame_REV1_ENST00000258428_chr2_100065798_-_AFF3_ENST00000317233_chr2_100185377_-_371aa
MRRGGWRKRAENDGWETWGGTMAAKVQKLEEQFRSDAAMQKDGTSSTIFSGVAITVNGYTDPSAEELRKLMMLHGGQYHVTTSRSKTTHI
IATNLPNAKIKELKGEKVIRPEWIVERPRSADTFMQEAKRMKHKADAMVEKFGKALNTAEAALSFIECGNAMEQGPMESKSPTTMTSETV
ELIRTAMRLKTHSGPNATPEDKQLAALCYRCLALLYWRMFRLKRDHAVKTSKALIDTFKNSSKAAQAPSPWGASGKSTGTPSPMSPNPSP
ASSVGSQGSLSNASALSPSTIVSIPQRIHQMAANHVSITNSILHSYDYWEMADNLAKENREFFNDLDLLMGPVTLHSSMEHLVQYSQQGL

>In-frame_REV1_ENST00000258428_chr2_100065798_-_AFF3_ENST00000409579_chr2_100185377_-_371aa
MRRGGWRKRAENDGWETWGGTMAAKVQKLEEQFRSDAAMQKDGTSSTIFSGVAITVNGYTDPSAEELRKLMMLHGGQYHVTTSRSKTTHI
IATNLPNAKIKELKGEKVIRPEWIVERPRSADTFMQEAKRMKHKADAMVEKFGKALNTAEAALSFIECGNAMEQGPMESKSPTTMTSETV
ELIRTAMRLKTHSGPNATPEDKQLAALCYRCLALLYWRMFRLKRDHAVKTSKALIDTFKNSSKAAQAPSPWGASGKSTGTPSPMSPNPSP
ASSVGSQGSLSNASALSPSTIVSIPQRIHQMAANHVSITNSILHSYDYWEMADNLAKENREFFNDLDLLMGPVTLHSSMEHLVQYSQQGL


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_REV1_ENST00000393445_chr2_100065798_-_AFF3_ENST00000409236_chr2_100185377_-_1113nt
ATGAGGCGAGGTGGATGGAGGAAGCGAGCTGAAAATGATGGCTGGGAAACATGGGGTGGGTATATGGCTGCCAAGGTCCAGAAATTGGAG
GAACAGTTTCGATCAGATGCTGCTATGCAGAAGGATGGGACTTCATCTACAATTTTTAGTGGAGTTGCCATCTATGTTAATGGATACACA
GATCCTTCCGCTGAGGAATTGAGAAAACTAATGATGTTGCATGGAGGTCAATACCATGTATATTATTCCAGATCTAAAACAACACATATT
ATTGCCACAAATCTTCCCAATGCCAAAATTAAAGAATTAAAGGGGGAAAAAGTAATTCGACCAGAATGGATTGTGGAAAGGCCTCGCAGT
GCCGATTATTTTATGCAAGAAGCTAAACGAATGAAGCATAAAGCAGATGCAATGGTGGAAAAGTTTGGAAAGGCTTTGAACTATGCTGAA
GCAGCATTGTCGTTTATCGAGTGTGGAAATGCAATGGAACAAGGCCCCATGGAATCCAAATCTCCTTATACGATGTATTCAGAAACAGTA
GAGCTCATCAGGTATGCTATGAGACTAAAAACCCACTCAGGCCCCAATGCCACACCAGAAGACAAACAACTGGCTGCATTATGTTACCGA
TGCCTGGCCCTCCTGTACTGGCGGATGTTTCGACTCAAAAGGGACCACGCTGTAAAGTATTCAAAAGCACTAATCGACTATTTCAAGAAC
TCATCTAAAGCCGCCCAAGCCCCATCTCCGTGGGGGGCCAGTGGAAAGAGCACTGGAACCCCATCCCCCATGTCTCCCAACCCCTCTCCC
GCCAGCTCCGTGGGGTCTCAGGGCAGCCTCTCCAACGCCAGCGCCCTGTCCCCGTCGACCATCGTCAGCATCCCACAGCGCATCCACCAG
ATGGCGGCCAACCACGTCAGCATCACCAACAGCATCCTGCACAGCTACGACTACTGGGAGATGGCCGACAACCTGGCCAAGGAAAACCGA
GAATTCTTCAACGACCTGGATCTGCTCATGGGGCCGGTCACCCTGCACAGCAGCATGGAGCACCTGGTCCAGTACTCCCAACAGGGCCTG

>In-frame_REV1_ENST00000393445_chr2_100065798_-_AFF3_ENST00000356421_chr2_100185377_-_1113nt
ATGAGGCGAGGTGGATGGAGGAAGCGAGCTGAAAATGATGGCTGGGAAACATGGGGTGGGTATATGGCTGCCAAGGTCCAGAAATTGGAG
GAACAGTTTCGATCAGATGCTGCTATGCAGAAGGATGGGACTTCATCTACAATTTTTAGTGGAGTTGCCATCTATGTTAATGGATACACA
GATCCTTCCGCTGAGGAATTGAGAAAACTAATGATGTTGCATGGAGGTCAATACCATGTATATTATTCCAGATCTAAAACAACACATATT
ATTGCCACAAATCTTCCCAATGCCAAAATTAAAGAATTAAAGGGGGAAAAAGTAATTCGACCAGAATGGATTGTGGAAAGGCCTCGCAGT
GCCGATTATTTTATGCAAGAAGCTAAACGAATGAAGCATAAAGCAGATGCAATGGTGGAAAAGTTTGGAAAGGCTTTGAACTATGCTGAA
GCAGCATTGTCGTTTATCGAGTGTGGAAATGCAATGGAACAAGGCCCCATGGAATCCAAATCTCCTTATACGATGTATTCAGAAACAGTA
GAGCTCATCAGGTATGCTATGAGACTAAAAACCCACTCAGGCCCCAATGCCACACCAGAAGACAAACAACTGGCTGCATTATGTTACCGA
TGCCTGGCCCTCCTGTACTGGCGGATGTTTCGACTCAAAAGGGACCACGCTGTAAAGTATTCAAAAGCACTAATCGACTATTTCAAGAAC
TCATCTAAAGCCGCCCAAGCCCCATCTCCGTGGGGGGCCAGTGGAAAGAGCACTGGAACCCCATCCCCCATGTCTCCCAACCCCTCTCCC
GCCAGCTCCGTGGGGTCTCAGGGCAGCCTCTCCAACGCCAGCGCCCTGTCCCCGTCGACCATCGTCAGCATCCCACAGCGCATCCACCAG
ATGGCGGCCAACCACGTCAGCATCACCAACAGCATCCTGCACAGCTACGACTACTGGGAGATGGCCGACAACCTGGCCAAGGAAAACCGA
GAATTCTTCAACGACCTGGATCTGCTCATGGGGCCGGTCACCCTGCACAGCAGCATGGAGCACCTGGTCCAGTACTCCCAACAGGGCCTG

>In-frame_REV1_ENST00000393445_chr2_100065798_-_AFF3_ENST00000317233_chr2_100185377_-_1113nt
ATGAGGCGAGGTGGATGGAGGAAGCGAGCTGAAAATGATGGCTGGGAAACATGGGGTGGGTATATGGCTGCCAAGGTCCAGAAATTGGAG
GAACAGTTTCGATCAGATGCTGCTATGCAGAAGGATGGGACTTCATCTACAATTTTTAGTGGAGTTGCCATCTATGTTAATGGATACACA
GATCCTTCCGCTGAGGAATTGAGAAAACTAATGATGTTGCATGGAGGTCAATACCATGTATATTATTCCAGATCTAAAACAACACATATT
ATTGCCACAAATCTTCCCAATGCCAAAATTAAAGAATTAAAGGGGGAAAAAGTAATTCGACCAGAATGGATTGTGGAAAGGCCTCGCAGT
GCCGATTATTTTATGCAAGAAGCTAAACGAATGAAGCATAAAGCAGATGCAATGGTGGAAAAGTTTGGAAAGGCTTTGAACTATGCTGAA
GCAGCATTGTCGTTTATCGAGTGTGGAAATGCAATGGAACAAGGCCCCATGGAATCCAAATCTCCTTATACGATGTATTCAGAAACAGTA
GAGCTCATCAGGTATGCTATGAGACTAAAAACCCACTCAGGCCCCAATGCCACACCAGAAGACAAACAACTGGCTGCATTATGTTACCGA
TGCCTGGCCCTCCTGTACTGGCGGATGTTTCGACTCAAAAGGGACCACGCTGTAAAGTATTCAAAAGCACTAATCGACTATTTCAAGAAC
TCATCTAAAGCCGCCCAAGCCCCATCTCCGTGGGGGGCCAGTGGAAAGAGCACTGGAACCCCATCCCCCATGTCTCCCAACCCCTCTCCC
GCCAGCTCCGTGGGGTCTCAGGGCAGCCTCTCCAACGCCAGCGCCCTGTCCCCGTCGACCATCGTCAGCATCCCACAGCGCATCCACCAG
ATGGCGGCCAACCACGTCAGCATCACCAACAGCATCCTGCACAGCTACGACTACTGGGAGATGGCCGACAACCTGGCCAAGGAAAACCGA
GAATTCTTCAACGACCTGGATCTGCTCATGGGGCCGGTCACCCTGCACAGCAGCATGGAGCACCTGGTCCAGTACTCCCAACAGGGCCTG

>In-frame_REV1_ENST00000393445_chr2_100065798_-_AFF3_ENST00000409579_chr2_100185377_-_1113nt
ATGAGGCGAGGTGGATGGAGGAAGCGAGCTGAAAATGATGGCTGGGAAACATGGGGTGGGTATATGGCTGCCAAGGTCCAGAAATTGGAG
GAACAGTTTCGATCAGATGCTGCTATGCAGAAGGATGGGACTTCATCTACAATTTTTAGTGGAGTTGCCATCTATGTTAATGGATACACA
GATCCTTCCGCTGAGGAATTGAGAAAACTAATGATGTTGCATGGAGGTCAATACCATGTATATTATTCCAGATCTAAAACAACACATATT
ATTGCCACAAATCTTCCCAATGCCAAAATTAAAGAATTAAAGGGGGAAAAAGTAATTCGACCAGAATGGATTGTGGAAAGGCCTCGCAGT
GCCGATTATTTTATGCAAGAAGCTAAACGAATGAAGCATAAAGCAGATGCAATGGTGGAAAAGTTTGGAAAGGCTTTGAACTATGCTGAA
GCAGCATTGTCGTTTATCGAGTGTGGAAATGCAATGGAACAAGGCCCCATGGAATCCAAATCTCCTTATACGATGTATTCAGAAACAGTA
GAGCTCATCAGGTATGCTATGAGACTAAAAACCCACTCAGGCCCCAATGCCACACCAGAAGACAAACAACTGGCTGCATTATGTTACCGA
TGCCTGGCCCTCCTGTACTGGCGGATGTTTCGACTCAAAAGGGACCACGCTGTAAAGTATTCAAAAGCACTAATCGACTATTTCAAGAAC
TCATCTAAAGCCGCCCAAGCCCCATCTCCGTGGGGGGCCAGTGGAAAGAGCACTGGAACCCCATCCCCCATGTCTCCCAACCCCTCTCCC
GCCAGCTCCGTGGGGTCTCAGGGCAGCCTCTCCAACGCCAGCGCCCTGTCCCCGTCGACCATCGTCAGCATCCCACAGCGCATCCACCAG
ATGGCGGCCAACCACGTCAGCATCACCAACAGCATCCTGCACAGCTACGACTACTGGGAGATGGCCGACAACCTGGCCAAGGAAAACCGA
GAATTCTTCAACGACCTGGATCTGCTCATGGGGCCGGTCACCCTGCACAGCAGCATGGAGCACCTGGTCCAGTACTCCCAACAGGGCCTG

>In-frame_REV1_ENST00000258428_chr2_100065798_-_AFF3_ENST00000409236_chr2_100185377_-_1113nt
ATGAGGCGAGGTGGATGGAGGAAGCGAGCTGAAAATGATGGCTGGGAAACATGGGGTGGGTATATGGCTGCCAAGGTCCAGAAATTGGAG
GAACAGTTTCGATCAGATGCTGCTATGCAGAAGGATGGGACTTCATCTACAATTTTTAGTGGAGTTGCCATCTATGTTAATGGATACACA
GATCCTTCCGCTGAGGAATTGAGAAAACTAATGATGTTGCATGGAGGTCAATACCATGTATATTATTCCAGATCTAAAACAACACATATT
ATTGCCACAAATCTTCCCAATGCCAAAATTAAAGAATTAAAGGGGGAAAAAGTAATTCGACCAGAATGGATTGTGGAAAGGCCTCGCAGT
GCCGATTATTTTATGCAAGAAGCTAAACGAATGAAGCATAAAGCAGATGCAATGGTGGAAAAGTTTGGAAAGGCTTTGAACTATGCTGAA
GCAGCATTGTCGTTTATCGAGTGTGGAAATGCAATGGAACAAGGCCCCATGGAATCCAAATCTCCTTATACGATGTATTCAGAAACAGTA
GAGCTCATCAGGTATGCTATGAGACTAAAAACCCACTCAGGCCCCAATGCCACACCAGAAGACAAACAACTGGCTGCATTATGTTACCGA
TGCCTGGCCCTCCTGTACTGGCGGATGTTTCGACTCAAAAGGGACCACGCTGTAAAGTATTCAAAAGCACTAATCGACTATTTCAAGAAC
TCATCTAAAGCCGCCCAAGCCCCATCTCCGTGGGGGGCCAGTGGAAAGAGCACTGGAACCCCATCCCCCATGTCTCCCAACCCCTCTCCC
GCCAGCTCCGTGGGGTCTCAGGGCAGCCTCTCCAACGCCAGCGCCCTGTCCCCGTCGACCATCGTCAGCATCCCACAGCGCATCCACCAG
ATGGCGGCCAACCACGTCAGCATCACCAACAGCATCCTGCACAGCTACGACTACTGGGAGATGGCCGACAACCTGGCCAAGGAAAACCGA
GAATTCTTCAACGACCTGGATCTGCTCATGGGGCCGGTCACCCTGCACAGCAGCATGGAGCACCTGGTCCAGTACTCCCAACAGGGCCTG

>In-frame_REV1_ENST00000258428_chr2_100065798_-_AFF3_ENST00000356421_chr2_100185377_-_1113nt
ATGAGGCGAGGTGGATGGAGGAAGCGAGCTGAAAATGATGGCTGGGAAACATGGGGTGGGTATATGGCTGCCAAGGTCCAGAAATTGGAG
GAACAGTTTCGATCAGATGCTGCTATGCAGAAGGATGGGACTTCATCTACAATTTTTAGTGGAGTTGCCATCTATGTTAATGGATACACA
GATCCTTCCGCTGAGGAATTGAGAAAACTAATGATGTTGCATGGAGGTCAATACCATGTATATTATTCCAGATCTAAAACAACACATATT
ATTGCCACAAATCTTCCCAATGCCAAAATTAAAGAATTAAAGGGGGAAAAAGTAATTCGACCAGAATGGATTGTGGAAAGGCCTCGCAGT
GCCGATTATTTTATGCAAGAAGCTAAACGAATGAAGCATAAAGCAGATGCAATGGTGGAAAAGTTTGGAAAGGCTTTGAACTATGCTGAA
GCAGCATTGTCGTTTATCGAGTGTGGAAATGCAATGGAACAAGGCCCCATGGAATCCAAATCTCCTTATACGATGTATTCAGAAACAGTA
GAGCTCATCAGGTATGCTATGAGACTAAAAACCCACTCAGGCCCCAATGCCACACCAGAAGACAAACAACTGGCTGCATTATGTTACCGA
TGCCTGGCCCTCCTGTACTGGCGGATGTTTCGACTCAAAAGGGACCACGCTGTAAAGTATTCAAAAGCACTAATCGACTATTTCAAGAAC
TCATCTAAAGCCGCCCAAGCCCCATCTCCGTGGGGGGCCAGTGGAAAGAGCACTGGAACCCCATCCCCCATGTCTCCCAACCCCTCTCCC
GCCAGCTCCGTGGGGTCTCAGGGCAGCCTCTCCAACGCCAGCGCCCTGTCCCCGTCGACCATCGTCAGCATCCCACAGCGCATCCACCAG
ATGGCGGCCAACCACGTCAGCATCACCAACAGCATCCTGCACAGCTACGACTACTGGGAGATGGCCGACAACCTGGCCAAGGAAAACCGA
GAATTCTTCAACGACCTGGATCTGCTCATGGGGCCGGTCACCCTGCACAGCAGCATGGAGCACCTGGTCCAGTACTCCCAACAGGGCCTG

>In-frame_REV1_ENST00000258428_chr2_100065798_-_AFF3_ENST00000317233_chr2_100185377_-_1113nt
ATGAGGCGAGGTGGATGGAGGAAGCGAGCTGAAAATGATGGCTGGGAAACATGGGGTGGGTATATGGCTGCCAAGGTCCAGAAATTGGAG
GAACAGTTTCGATCAGATGCTGCTATGCAGAAGGATGGGACTTCATCTACAATTTTTAGTGGAGTTGCCATCTATGTTAATGGATACACA
GATCCTTCCGCTGAGGAATTGAGAAAACTAATGATGTTGCATGGAGGTCAATACCATGTATATTATTCCAGATCTAAAACAACACATATT
ATTGCCACAAATCTTCCCAATGCCAAAATTAAAGAATTAAAGGGGGAAAAAGTAATTCGACCAGAATGGATTGTGGAAAGGCCTCGCAGT
GCCGATTATTTTATGCAAGAAGCTAAACGAATGAAGCATAAAGCAGATGCAATGGTGGAAAAGTTTGGAAAGGCTTTGAACTATGCTGAA
GCAGCATTGTCGTTTATCGAGTGTGGAAATGCAATGGAACAAGGCCCCATGGAATCCAAATCTCCTTATACGATGTATTCAGAAACAGTA
GAGCTCATCAGGTATGCTATGAGACTAAAAACCCACTCAGGCCCCAATGCCACACCAGAAGACAAACAACTGGCTGCATTATGTTACCGA
TGCCTGGCCCTCCTGTACTGGCGGATGTTTCGACTCAAAAGGGACCACGCTGTAAAGTATTCAAAAGCACTAATCGACTATTTCAAGAAC
TCATCTAAAGCCGCCCAAGCCCCATCTCCGTGGGGGGCCAGTGGAAAGAGCACTGGAACCCCATCCCCCATGTCTCCCAACCCCTCTCCC
GCCAGCTCCGTGGGGTCTCAGGGCAGCCTCTCCAACGCCAGCGCCCTGTCCCCGTCGACCATCGTCAGCATCCCACAGCGCATCCACCAG
ATGGCGGCCAACCACGTCAGCATCACCAACAGCATCCTGCACAGCTACGACTACTGGGAGATGGCCGACAACCTGGCCAAGGAAAACCGA
GAATTCTTCAACGACCTGGATCTGCTCATGGGGCCGGTCACCCTGCACAGCAGCATGGAGCACCTGGTCCAGTACTCCCAACAGGGCCTG

>In-frame_REV1_ENST00000258428_chr2_100065798_-_AFF3_ENST00000409579_chr2_100185377_-_1113nt
ATGAGGCGAGGTGGATGGAGGAAGCGAGCTGAAAATGATGGCTGGGAAACATGGGGTGGGTATATGGCTGCCAAGGTCCAGAAATTGGAG
GAACAGTTTCGATCAGATGCTGCTATGCAGAAGGATGGGACTTCATCTACAATTTTTAGTGGAGTTGCCATCTATGTTAATGGATACACA
GATCCTTCCGCTGAGGAATTGAGAAAACTAATGATGTTGCATGGAGGTCAATACCATGTATATTATTCCAGATCTAAAACAACACATATT
ATTGCCACAAATCTTCCCAATGCCAAAATTAAAGAATTAAAGGGGGAAAAAGTAATTCGACCAGAATGGATTGTGGAAAGGCCTCGCAGT
GCCGATTATTTTATGCAAGAAGCTAAACGAATGAAGCATAAAGCAGATGCAATGGTGGAAAAGTTTGGAAAGGCTTTGAACTATGCTGAA
GCAGCATTGTCGTTTATCGAGTGTGGAAATGCAATGGAACAAGGCCCCATGGAATCCAAATCTCCTTATACGATGTATTCAGAAACAGTA
GAGCTCATCAGGTATGCTATGAGACTAAAAACCCACTCAGGCCCCAATGCCACACCAGAAGACAAACAACTGGCTGCATTATGTTACCGA
TGCCTGGCCCTCCTGTACTGGCGGATGTTTCGACTCAAAAGGGACCACGCTGTAAAGTATTCAAAAGCACTAATCGACTATTTCAAGAAC
TCATCTAAAGCCGCCCAAGCCCCATCTCCGTGGGGGGCCAGTGGAAAGAGCACTGGAACCCCATCCCCCATGTCTCCCAACCCCTCTCCC
GCCAGCTCCGTGGGGTCTCAGGGCAGCCTCTCCAACGCCAGCGCCCTGTCCCCGTCGACCATCGTCAGCATCCCACAGCGCATCCACCAG
ATGGCGGCCAACCACGTCAGCATCACCAACAGCATCCTGCACAGCTACGACTACTGGGAGATGGCCGACAACCTGGCCAAGGAAAACCGA
GAATTCTTCAACGACCTGGATCTGCTCATGGGGCCGGTCACCCTGCACAGCAGCATGGAGCACCTGGTCCAGTACTCCCAACAGGGCCTG


* Fusion transcript sequences (Full-length transcript).
>In-frame_REV1_ENST00000393445_chr2_100065798_-_AFF3_ENST00000409236_chr2_100185377_-_6893nt
GGGAGCGTGGACCGCGGCGCTGCTCAGCGGTGGGGCTGCCTTCCCCCGGCCCTCCTCCCTGGTCCCTGGCGAGGGCACTGGCGGCGGCGG
GGCCGGGGTCCGCAAGGCCGGAGAAGGCCGCCGGGCCCGGGCATGGTGGTCTGGGGCAACGCGGAAGAAGCTCCACCATGAGGCGAGGTG
GATGGAGGAAGCGAGCTGAAAATGATGGCTGGGAAACATGGGGTGGGTATATGGCTGCCAAGGTCCAGAAATTGGAGGAACAGTTTCGAT
CAGATGCTGCTATGCAGAAGGATGGGACTTCATCTACAATTTTTAGTGGAGTTGCCATCTATGTTAATGGATACACAGATCCTTCCGCTG
AGGAATTGAGAAAACTAATGATGTTGCATGGAGGTCAATACCATGTATATTATTCCAGATCTAAAACAACACATATTATTGCCACAAATC
TTCCCAATGCCAAAATTAAAGAATTAAAGGGGGAAAAAGTAATTCGACCAGAATGGATTGTGGAAAGGCCTCGCAGTGCCGATTATTTTA
TGCAAGAAGCTAAACGAATGAAGCATAAAGCAGATGCAATGGTGGAAAAGTTTGGAAAGGCTTTGAACTATGCTGAAGCAGCATTGTCGT
TTATCGAGTGTGGAAATGCAATGGAACAAGGCCCCATGGAATCCAAATCTCCTTATACGATGTATTCAGAAACAGTAGAGCTCATCAGGT
ATGCTATGAGACTAAAAACCCACTCAGGCCCCAATGCCACACCAGAAGACAAACAACTGGCTGCATTATGTTACCGATGCCTGGCCCTCC
TGTACTGGCGGATGTTTCGACTCAAAAGGGACCACGCTGTAAAGTATTCAAAAGCACTAATCGACTATTTCAAGAACTCATCTAAAGCCG
CCCAAGCCCCATCTCCGTGGGGGGCCAGTGGAAAGAGCACTGGAACCCCATCCCCCATGTCTCCCAACCCCTCTCCCGCCAGCTCCGTGG
GGTCTCAGGGCAGCCTCTCCAACGCCAGCGCCCTGTCCCCGTCGACCATCGTCAGCATCCCACAGCGCATCCACCAGATGGCGGCCAACC
ACGTCAGCATCACCAACAGCATCCTGCACAGCTACGACTACTGGGAGATGGCCGACAACCTGGCCAAGGAAAACCGAGAATTCTTCAACG
ACCTGGATCTGCTCATGGGGCCGGTCACCCTGCACAGCAGCATGGAGCACCTGGTCCAGTACTCCCAACAGGGCCTGCACTGGCTGCGGA
ACAGCGCCCACCTGTCATAGGGACCTCACCCTGGGGCCAGAGTGGGCTCTGGTCTCCACAGATGGCTCAACGTTTTTGGACACTGTGCTA
CTGAAACTCCCAGCCACAGCATTTATCAGACTGCGGTGAACATTTCCTCAGCATTGAACAATGATCTTTTGCAGGGCATGTGTGTTTGTA
TGTGTGGGTATATAAGAAGCCGCCTGTGTATGTGTGTAAGATACACAGCTCTTCAGAACACACCTTCTTTGTCTAGTTTCCATAATCCCA
GGCTAGACAAAGTGATCAGAGGTTTCTGACTAGAGGAAGTACACACACACACACACACACACACACACACCGTACACTCACACACAATCA
CAGACACACACTTTCTATTCCATTCCAGTGCTAAACCGTGACTTCTTAGAAAATTCAACCAAAATCTCATGGGTTAGTTAACCAGGTGCA
ATACAGCACACCAAAAGCTTGACTGCCAGTGAAGATGGACCTGCTCTTATACTGTTGATTACTTTCAGTATTAATATACTATTCCCCAAT
TATTTTTTGATTGGTATGTATTAATGGGTAATTGAATAATGAAAATAAGCCAGGTATTTTTGTGCCGGAAGTTTACTAGATTGCATGTTA
CCAAATACCCTGCTCTTCCTCTAATTCCCTTCCCCCATCTGACTCTATTATCAACTAAATGCATTCCAGGCAAACAGATGGACACTCACA
GCCCTTCCCAGCCCCACCTCCAAGTAGTATGCAAATGGCACTGAGATTTAGCAAAAACGCGGCGTCTTTGAAAGTTAACAGACACTAAGG
TAGCAGTGCCTGTGTGTTGGAGCTCAGTTAGGAGTTGAAGTTTTCTGCACCTGTGATAACAAGCCCACCAGCCACATGCATTTCTTCTTC
CTGCCACTGTGACTCGGTGGCTGTAGAGCCACATGGCATTTGTCAGCCAATCTGTTTCAAGTCTTTTCTTTCCACCAATAGCTTTCTTAC
AGATTTTCTTGGCTAAATGAGGCCATTACCTAGATTGTCCCTTCAGTAGGAGCCTGAATCCTTCGCTTACCAGGCTGAGAGCTATTTGCC
ATGATAATGCTGATTCTCTCACTCCTCATGCAGAATGTGCACCTGCAGCCCTTTGATGCGTTTTGATTTGGGGGCGATTTTTCAGGCTTT
GATTAGCAGGCTGCTTGCAATGCAGAAGATCACAGTTCCTTTCTGGGGCAGCAGCAACCAGAGCCTCTTCCTGTGTCCTGTGTGTCTGGT
ATGTTTACACCTTGCTCTGAGTTTTTCTCTTGTTTTCTTTTTTTAATTAAGTTTACATTTTAGTTTCTTTGACATCTTGTTTACAGTTTT
TGTCTGATGTTTTTTCTTTTGTAGTGTCTTATGCCCTAGATTTAGTCATCTTGTTAAATATATTTGGATATGAAATCTTGACGAAAAGAA
AATAACTCCTGAAAAAGAGGGTCTATCTTGCCACACGTTAAAAACAAAAATAATGTCCTTGTGGCCTCTTACTTGATAAAGTTGCACCAG
GACGGTCTGAGAAAGGCAGGCGGTGTAATATGTGGTGCAATCCATTTTTTCAAGGTGATGACGGCACAAAATACTTAGACTAGATGCTGA
TCCATAAACATTCACTGATATTCTTACAGGTTGGTTTGCAGTGTTAACATTTTTGTTAGCCTGATCTGTAGGTGGGAAGTAAGATCATCA
TAATTCCTTAGCTCTGAGCACTGATTCAAAATTGTATAAATGACTGAACAACTTAGATGATTTGAAATTAATTGAAAATAAGAAGGGCTT
GTGGAATTTGCATTTGGCTTTGGCCTTCAAGCATTTGGAAATATTAAGAGAATTTCCATTTTACATGTCTCCAACTGGGGTGCTTCTTAC
AACCCTTTCACTTTTTTTTTGAGACGAGTTTCGCTCTGTTGCCCAGGCTGGAGTGCAGTGGCACGATCTCGGCTCACTGCATCCTCTGCC
TCCTGGGTTCAAGTGATTGTCCCGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGTGTGCACTACCATGCCCAGCTAATTTTTGTGTTTT
TAGTAGAGACTGGGTTTCACCATGTTGGCCAGGCTCGTCTCAAACTCCTGACCTCAGGTGATCTACCCGCCTCCACCTCCCAAAGTGTTG
TGATTACAGGCGTGAGCCACCACACCCAGCCCTTTCACTAATTTTTGGCAGAGTTCACAATCCCATCCTATGTCAGAAACTTGAACCTAA
CTTAAGAAATTTTGAGTCATTTTTTTGGAGGACTGAGGCTTTGTTCTACCTACTCTTGAAGAATCCTGATGAAATATTCAAACACATAAA
GGGATGGCCCTGGAGGTCTATCCTGCATACCTGGAGAGCTTCTCTGGTCCTGCCCACCTTGAAAGTTGCAGACTTTGTTGTAACATCTAT
GTGATGAGCTTCCCTGTGAAGCCCCATTTGACAGGTGGGCCAGCAGTGTTTTATCAGCACTCTGATGGCCCACATTTCCCAGGAAAACTT
CTTGAAACTTACCGTTGTGGGCAGTGGTCAGAGCGTGTAGTTCTTATGACTGTCTTGTTTCATCTGTGGAGCACGTGTGGAGCACGTTGG
TACAGCAGTTTCTGTGGGGTTTGGCATGGGTGATTTTGGTTAGTAACCATCCTCCAATTGTTGCTTGTGAAAGTCATTCATAACTTGTTC
CTTTTACTTAGTTTTGTTGTTACTGCTGTTGTTGTTGGTTTGGTTGGTTTTGAGACCGGGTCTGGCTCTGTAGCCCAAGCTGGAATGCGG
TGGCGCGATCATGGCTCCCTGCAGCCTCAAACTCCTGGGCTCAAGCAATCCTCCTGCCTCAGCCTCCCAAGCAGCTGGGAAGATAGGCAC
GTGCCACCACACCCGGCTAATTTTTTCTTTATTTTTTTTGTAGAGATGGGGGTCTCACTATGTTGCCCAGGCTGGTCTCAAACTCCTGGG
CTCAAGCGATCCTTTGGCCTCGGCCTCCCAAAGTGCATGAGCCACCATGCCTGGCCTGTTTAGTTTTGTTTCAAGTTGAAATACCTTTCT
TGTGTTTTCTAATTAGAAAAGTAATATCTACTCATTGTAAAAACTCAAACAGTGCAGAAATGTAGAAAGTAGAAAGTGTAAGTCCCTGGT
TGTCCCTTCTGCCTGAGACAACCACTGCTCACAGTTTGATGTATATCCTTCCAGAGACTCTCAAATTTAAGCAAATAATTTTTATTACCA
TGTCTTTTTATTTGAAGACGTACATTTGCCTCCAAAGTTCAACACAAGTTCAACTGACCATATCCTTCCATGACCTGAATAGATGCTATC
CTTTATCACGATGTTCAATTGCCTTTGAAAGAGAGTAGTCCAGGTATATTCCTGATCAAAATTTGGCATTTTTGATGATACTACTCTACA
CAGATCAGACTCATGTGCAGAATCGTGCCTGGAGAGAGAGGTTTGGTTAAGACAGAGATTTCTGGAAACATTCAAATTGCAAATGGAAAC
TTGAAACCCACAATCTAATGAGGAATGTACTGGAAAAATAATCTGAAGAGTTGACAAATTGTGTACTAGATTGAACACATGGAATGCAAT
GCAATGAGACTTTCTGCACTAAAACTTATCCTCATATGTACAACAATGATGTGTGTATTATATAACAGTGATGTGTACATTTCTGACACC
CCATACATAATATACACAGTTTGTATAAATGCATACATTTAAAAATATATATGTACAATACAGCTAACATAAAACTGTAGTACGCCTGAA
GGATATTACTAGTGCCTAATATTGAGTATGAGTCACTGCGTGTTCGCATCAACTTGGAAGTGCAGTAATTGTTATAAAATTAATCAGTGC
AGCCAACATTATTTATGAATCACATCTTTGAAACTGTGCAGTAGCATATACATATATATTTTTAAATAACATTTTTCACAGTTTTCCAGA
GTTACTGTTGAAATCTGCATCACCAAAAAAAAAAAAAAGCAAGATTTTTTTAACAATGTAGACACTCTTCAGACCCAGTAATCTGCGTGT
GATTTCCTATTTGTAGATTCCCAAGAGACTTTAGCAGTCACCAGCCTTAATGCATGTACAGGATATTATTGTGACTTAATTTATCTGCAG
TTTTTAATCCATGTGAAATTGGAATTTATAAACGGACTTGGATTAAACATGTCTGCCTTTCTAAGGTTGCAAATGTTACATTAAATGATT
TATGTTGTAAATGAGAGAAGTTGAGTTGTACGTAAAAGACATCCACCAATTTCTGTGAATATTTTTACACGGAAACTTGAGAATCAAAAT
ACGTTCAAGTCAGTTGTTCTGGCTCCCAGTTTATAATCTCGAAAAGCAATCTTTTTGTTTCATAAATGGCTTAAATGTAGCTCCCACAGA
TTATCAGTATGAAGTCTGACATTTTTCATGGAAAAGAAGTATGTTTTTCTTCATTATAACTATAGTTTACTATTTGTCTTTGCTATTTCC
TGATACATACACATACGCACACACGCGCGCACATGCATGCACGTATGCACATGCACGCTCCCAGTGTCCCAGTGAAGGCTCAACAGGAAG
CTTGAGAAGGTCATCTCAATGGCCACAGGGTTCCTGTTCAACCAGTAGCCCTGGGATGCCGCTTTGCTTGTCATTCTTTAGTGTCACAAG
TTAGTTCCCTGACTTGTGTGCAGTCAGGGAACTGCACACAACTGAAACCAACATGGTGGAATCATGTTTGCAATATTTGGTTGAGTAAAA
TAAGATAATTTTGAACTAAAGAAGACGGAGGCATTAGACCAGTGGCTTGACATGAAGCATCCCCTATGTGGGAGGGTAAGTTTGTTAACT
TCATTTTTAGTCTTATCTCCAACCCTTTTCCTTATCCTCCTCCCCAAACTAAAGAAGCAGAAACAGCAACAAAAGCAAAACCATCCCTTC
ACCTGATCCAGCCCATGTCCTTAGATTCAAATATCCTTTGTCTTTTTCCCATTATACCATCTGACATAACTCACTCGTGTCTAGAGAGAA
AAATGCAGAAAGGGTTTGTTTGCAGATGGGCAGTTCAGTTGAGTCCTCATTAACCAGGCAGAGGGGTGCAGAAGAAGCCTGACTCAGGGT
CACCATGGAGAACTCCTCATCCCAGAGATGGGTGGGACAGGAACTTGGCTTTGCTTCACCAACCACTGAGCTTGATACTCTTTCAGAGGT
GGTTTGTGCTAAGAAACACCCAGCAGTCTTTCAAGAACGTTCTCTTCTGTAGCTTTGCCTGCTACACAGCTGAAGTCTGTCCCTATAAGA
ATTATATTTGTAAAAAGTAATACATTTTCGAAGAAACCCGGATCAAGTGGAATCTTGAAAGTTTTTTTAATGAAAGGGGAAAAACAACCT
GACCACATAAACTGCACTTCCAACCATTTGGAACCAGAGTTTATGTCCTCATTTTCCCATTCTCAGAAGAGCACAGTTTTTCAATATTAC
AACTTCCTGGCAAATAGCACAAGAAATGTTCAGACTTGAGATTTGTGTTCCCTTTGTCCAGATTATTCTGTATATGTCACCAAAGGGGTT

>In-frame_REV1_ENST00000393445_chr2_100065798_-_AFF3_ENST00000356421_chr2_100185377_-_5498nt
GGGAGCGTGGACCGCGGCGCTGCTCAGCGGTGGGGCTGCCTTCCCCCGGCCCTCCTCCCTGGTCCCTGGCGAGGGCACTGGCGGCGGCGG
GGCCGGGGTCCGCAAGGCCGGAGAAGGCCGCCGGGCCCGGGCATGGTGGTCTGGGGCAACGCGGAAGAAGCTCCACCATGAGGCGAGGTG
GATGGAGGAAGCGAGCTGAAAATGATGGCTGGGAAACATGGGGTGGGTATATGGCTGCCAAGGTCCAGAAATTGGAGGAACAGTTTCGAT
CAGATGCTGCTATGCAGAAGGATGGGACTTCATCTACAATTTTTAGTGGAGTTGCCATCTATGTTAATGGATACACAGATCCTTCCGCTG
AGGAATTGAGAAAACTAATGATGTTGCATGGAGGTCAATACCATGTATATTATTCCAGATCTAAAACAACACATATTATTGCCACAAATC
TTCCCAATGCCAAAATTAAAGAATTAAAGGGGGAAAAAGTAATTCGACCAGAATGGATTGTGGAAAGGCCTCGCAGTGCCGATTATTTTA
TGCAAGAAGCTAAACGAATGAAGCATAAAGCAGATGCAATGGTGGAAAAGTTTGGAAAGGCTTTGAACTATGCTGAAGCAGCATTGTCGT
TTATCGAGTGTGGAAATGCAATGGAACAAGGCCCCATGGAATCCAAATCTCCTTATACGATGTATTCAGAAACAGTAGAGCTCATCAGGT
ATGCTATGAGACTAAAAACCCACTCAGGCCCCAATGCCACACCAGAAGACAAACAACTGGCTGCATTATGTTACCGATGCCTGGCCCTCC
TGTACTGGCGGATGTTTCGACTCAAAAGGGACCACGCTGTAAAGTATTCAAAAGCACTAATCGACTATTTCAAGAACTCATCTAAAGCCG
CCCAAGCCCCATCTCCGTGGGGGGCCAGTGGAAAGAGCACTGGAACCCCATCCCCCATGTCTCCCAACCCCTCTCCCGCCAGCTCCGTGG
GGTCTCAGGGCAGCCTCTCCAACGCCAGCGCCCTGTCCCCGTCGACCATCGTCAGCATCCCACAGCGCATCCACCAGATGGCGGCCAACC
ACGTCAGCATCACCAACAGCATCCTGCACAGCTACGACTACTGGGAGATGGCCGACAACCTGGCCAAGGAAAACCGAGAATTCTTCAACG
ACCTGGATCTGCTCATGGGGCCGGTCACCCTGCACAGCAGCATGGAGCACCTGGTCCAGTACTCCCAACAGGGCCTGCACTGGCTGCGGA
ACAGCGCCCACCTGTCATAGGGACCTCACCCTGGGGCCAGAGTGGGCTCTGGTCTCCACAGATGGCTCAACGTTTTTGGACACTGTGCTA
CTGAAACTCCCAGCCACAGCATTTATCAGACTGCGGTGAACATTTCCTCAGCATTGAACAATGATCTTTTGCAGGGCATGTGTGTTTGTA
TGTGTGGGTATATAAGAAGCCGCCTGTGTATGTGTGTAAGATACACAGCTCTTCAGAACACACCTTCTTTGTCTAGTTTCCATAATCCCA
GGCTAGACAAAGTGATCAGAGGTTTCTGACTAGAGGAAGTACACACACACACACACACACACACACACACCGTACACTCACACACAATCA
CAGACACACACTTTCTATTCCATTCCAGTGCTAAACCGTGACTTCTTAGAAAATTCAACCAAAATCTCATGGGTTAGTTAACCAGGTGCA
ATACAGCACACCAAAAGCTTGACTGCCAGTGAAGATGGACCTGCTCTTATACTGTTGATTACTTTCAGTATTAATATACTATTCCCCAAT
TATTTTTTGATTGGTATGTATTAATGGGTAATTGAATAATGAAAATAAGCCAGGTATTTTTGTGCCGGAAGTTTACTAGATTGCATGTTA
CCAAATACCCTGCTCTTCCTCTAATTCCCTTCCCCCATCTGACTCTATTATCAACTAAATGCATTCCAGGCAAACAGATGGACACTCACA
GCCCTTCCCAGCCCCACCTCCAAGTAGTATGCAAATGGCACTGAGATTTAGCAAAAACGCGGCGTCTTTGAAAGTTAACAGACACTAAGG
TAGCAGTGCCTGTGTGTTGGAGCTCAGTTAGGAGTTGAAGTTTTCTGCACCTGTGATAACAAGCCCACCAGCCACATGCATTTCTTCTTC
CTGCCACTGTGACTCGGTGGCTGTAGAGCCACATGGCATTTGTCAGCCAATCTGTTTCAAGTCTTTTCTTTCCACCAATAGCTTTCTTAC
AGATTTTCTTGGCTAAATGAGGCCATTACCTAGATTGTCCCTTCAGTAGGAGCCTGAATCCTTCGCTTACCAGGCTGAGAGCTATTTGCC
ATGATAATGCTGATTCTCTCACTCCTCATGCAGAATGTGCACCTGCAGCCCTTTGATGCGTTTTGATTTGGGGGCGATTTTTCAGGCTTT
GATTAGCAGGCTGCTTGCAATGCAGAAGATCACAGTTCCTTTCTGGGGCAGCAGCAACCAGAGCCTCTTCCTGTGTCCTGTGTGTCTGGT
ATGTTTACACCTTGCTCTGAGTTTTTCTCTTGTTTTCTTTTTTTAATTAAGTTTACATTTTAGTTTCTTTGACATCTTGTTTACAGTTTT
TGTCTGATGTTTTTTCTTTTGTAGTGTCTTATGCCCTAGATTTAGTCATCTTGTTAAATATATTTGGATATGAAATCTTGACGAAAAGAA
AATAACTCCTGAAAAAGAGGGTCTATCTTGCCACACGTTAAAAACAAAAATAATGTCCTTGTGGCCTCTTACTTGATAAAGTTGCACCAG
GACGGTCTGAGAAAGGCAGGCGGTGTAATATGTGGTGCAATCCATTTTTTCAAGGTGATGACGGCACAAAATACTTAGACTAGATGCTGA
TCCATAAACATTCACTGATATTCTTACAGGTTGGTTTGCAGTGTTAACATTTTTGTTAGCCTGATCTGTAGGTGGGAAGTAAGATCATCA
TAATTCCTTAGCTCTGAGCACTGATTCAAAATTGTATAAATGACTGAACAACTTAGATGATTTGAAATTAATTGAAAATAAGAAGGGCTT
GTGGAATTTGCATTTGGCTTTGGCCTTCAAGCATTTGGAAATATTAAGAGAATTTCCATTTTACATGTCTCCAACTGGGGTGCTTCTTAC
AACCCTTTCACTTTTTTTTTGAGACGAGTTTCGCTCTGTTGCCCAGGCTGGAGTGCAGTGGCACGATCTCGGCTCACTGCATCCTCTGCC
TCCTGGGTTCAAGTGATTGTCCCGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGTGTGCACTACCATGCCCAGCTAATTTTTGTGTTTT
TAGTAGAGACTGGGTTTCACCATGTTGGCCAGGCTCGTCTCAAACTCCTGACCTCAGGTGATCTACCCGCCTCCACCTCCCAAAGTGTTG
TGATTACAGGCGTGAGCCACCACACCCAGCCCTTTCACTAATTTTTGGCAGAGTTCACAATCCCATCCTATGTCAGAAACTTGAACCTAA
CTTAAGAAATTTTGAGTCATTTTTTTGGAGGACTGAGGCTTTGTTCTACCTACTCTTGAAGAATCCTGATGAAATATTCAAACACATAAA
GGGATGGCCCTGGAGGTCTATCCTGCATACCTGGAGAGCTTCTCTGGTCCTGCCCACCTTGAAAGTTGCAGACTTTGTTGTAACATCTAT
GTGATGAGCTTCCCTGTGAAGCCCCATTTGACAGGTGGGCCAGCAGTGTTTTATCAGCACTCTGATGGCCCACATTTCCCAGGAAAACTT
CTTGAAACTTACCGTTGTGGGCAGTGGTCAGAGCGTGTAGTTCTTATGACTGTCTTGTTTCATCTGTGGAGCACGTGTGGAGCACGTTGG
TACAGCAGTTTCTGTGGGGTTTGGCATGGGTGATTTTGGTTAGTAACCATCCTCCAATTGTTGCTTGTGAAAGTCATTCATAACTTGTTC
CTTTTACTTAGTTTTGTTGTTACTGCTGTTGTTGTTGGTTTGGTTGGTTTTGAGACCGGGTCTGGCTCTGTAGCCCAAGCTGGAATGCGG
TGGCGCGATCATGGCTCCCTGCAGCCTCAAACTCCTGGGCTCAAGCAATCCTCCTGCCTCAGCCTCCCAAGCAGCTGGGAAGATAGGCAC
GTGCCACCACACCCGGCTAATTTTTTCTTTATTTTTTTTGTAGAGATGGGGGTCTCACTATGTTGCCCAGGCTGGTCTCAAACTCCTGGG
CTCAAGCGATCCTTTGGCCTCGGCCTCCCAAAGTGCATGAGCCACCATGCCTGGCCTGTTTAGTTTTGTTTCAAGTTGAAATACCTTTCT
TGTGTTTTCTAATTAGAAAAGTAATATCTACTCATTGTAAAAACTCAAACAGTGCAGAAATGTAGAAAGTAGAAAGTGTAAGTCCCTGGT
TGTCCCTTCTGCCTGAGACAACCACTGCTCACAGTTTGATGTATATCCTTCCAGAGACTCTCAAATTTAAGCAAATAATTTTTATTACCA
TGTCTTTTTATTTGAAGACGTACATTTGCCTCCAAAGTTCAACACAAGTTCAACTGACCATATCCTTCCATGACCTGAATAGATGCTATC
CTTTATCACGATGTTCAATTGCCTTTGAAAGAGAGTAGTCCAGGTATATTCCTGATCAAAATTTGGCATTTTTGATGATACTACTCTACA
CAGATCAGACTCATGTGCAGAATCGTGCCTGGAGAGAGAGGTTTGGTTAAGACAGAGATTTCTGGAAACATTCAAATTGCAAATGGAAAC
TTGAAACCCACAATCTAATGAGGAATGTACTGGAAAAATAATCTGAAGAGTTGACAAATTGTGTACTAGATTGAACACATGGAATGCAAT
GCAATGAGACTTTCTGCACTAAAACTTATCCTCATATGTACAACAATGATGTGTGTATTATATAACAGTGATGTGTACATTTCTGACACC
CCATACATAATATACACAGTTTGTATAAATGCATACATTTAAAAATATATATGTACAATACAGCTAACATAAAACTGTAGTACGCCTGAA
GGATATTACTAGTGCCTAATATTGAGTATGAGTCACTGCGTGTTCGCATCAACTTGGAAGTGCAGTAATTGTTATAAAATTAATCAGTGC
AGCCAACATTATTTATGAATCACATCTTTGAAACTGTGCAGTAGCATATACATATATATTTTTAAATAACATTTTTCACAGTTTTCCAGA
GTTACTGTTGAAATCTGCATCACCAAAAAAAAAAAAAAGCAAGATTTTTTTAACAATGTAGACACTCTTCAGACCCAGTAATCTGCGTGT
GATTTCCTATTTGTAGATTCCCAAGAGACTTTAGCAGTCACCAGCCTTAATGCATGTACAGGATATTATTGTGACTTAATTTATCTGCAG
TTTTTAATCCATGTGAAATTGGAATTTATAAACGGACTTGGATTAAACATGTCTGCCTTTCTAAGGTTGCAAATGTTACATTAAATGATT

>In-frame_REV1_ENST00000393445_chr2_100065798_-_AFF3_ENST00000317233_chr2_100185377_-_5498nt
GGGAGCGTGGACCGCGGCGCTGCTCAGCGGTGGGGCTGCCTTCCCCCGGCCCTCCTCCCTGGTCCCTGGCGAGGGCACTGGCGGCGGCGG
GGCCGGGGTCCGCAAGGCCGGAGAAGGCCGCCGGGCCCGGGCATGGTGGTCTGGGGCAACGCGGAAGAAGCTCCACCATGAGGCGAGGTG
GATGGAGGAAGCGAGCTGAAAATGATGGCTGGGAAACATGGGGTGGGTATATGGCTGCCAAGGTCCAGAAATTGGAGGAACAGTTTCGAT
CAGATGCTGCTATGCAGAAGGATGGGACTTCATCTACAATTTTTAGTGGAGTTGCCATCTATGTTAATGGATACACAGATCCTTCCGCTG
AGGAATTGAGAAAACTAATGATGTTGCATGGAGGTCAATACCATGTATATTATTCCAGATCTAAAACAACACATATTATTGCCACAAATC
TTCCCAATGCCAAAATTAAAGAATTAAAGGGGGAAAAAGTAATTCGACCAGAATGGATTGTGGAAAGGCCTCGCAGTGCCGATTATTTTA
TGCAAGAAGCTAAACGAATGAAGCATAAAGCAGATGCAATGGTGGAAAAGTTTGGAAAGGCTTTGAACTATGCTGAAGCAGCATTGTCGT
TTATCGAGTGTGGAAATGCAATGGAACAAGGCCCCATGGAATCCAAATCTCCTTATACGATGTATTCAGAAACAGTAGAGCTCATCAGGT
ATGCTATGAGACTAAAAACCCACTCAGGCCCCAATGCCACACCAGAAGACAAACAACTGGCTGCATTATGTTACCGATGCCTGGCCCTCC
TGTACTGGCGGATGTTTCGACTCAAAAGGGACCACGCTGTAAAGTATTCAAAAGCACTAATCGACTATTTCAAGAACTCATCTAAAGCCG
CCCAAGCCCCATCTCCGTGGGGGGCCAGTGGAAAGAGCACTGGAACCCCATCCCCCATGTCTCCCAACCCCTCTCCCGCCAGCTCCGTGG
GGTCTCAGGGCAGCCTCTCCAACGCCAGCGCCCTGTCCCCGTCGACCATCGTCAGCATCCCACAGCGCATCCACCAGATGGCGGCCAACC
ACGTCAGCATCACCAACAGCATCCTGCACAGCTACGACTACTGGGAGATGGCCGACAACCTGGCCAAGGAAAACCGAGAATTCTTCAACG
ACCTGGATCTGCTCATGGGGCCGGTCACCCTGCACAGCAGCATGGAGCACCTGGTCCAGTACTCCCAACAGGGCCTGCACTGGCTGCGGA
ACAGCGCCCACCTGTCATAGGGACCTCACCCTGGGGCCAGAGTGGGCTCTGGTCTCCACAGATGGCTCAACGTTTTTGGACACTGTGCTA
CTGAAACTCCCAGCCACAGCATTTATCAGACTGCGGTGAACATTTCCTCAGCATTGAACAATGATCTTTTGCAGGGCATGTGTGTTTGTA
TGTGTGGGTATATAAGAAGCCGCCTGTGTATGTGTGTAAGATACACAGCTCTTCAGAACACACCTTCTTTGTCTAGTTTCCATAATCCCA
GGCTAGACAAAGTGATCAGAGGTTTCTGACTAGAGGAAGTACACACACACACACACACACACACACACACCGTACACTCACACACAATCA
CAGACACACACTTTCTATTCCATTCCAGTGCTAAACCGTGACTTCTTAGAAAATTCAACCAAAATCTCATGGGTTAGTTAACCAGGTGCA
ATACAGCACACCAAAAGCTTGACTGCCAGTGAAGATGGACCTGCTCTTATACTGTTGATTACTTTCAGTATTAATATACTATTCCCCAAT
TATTTTTTGATTGGTATGTATTAATGGGTAATTGAATAATGAAAATAAGCCAGGTATTTTTGTGCCGGAAGTTTACTAGATTGCATGTTA
CCAAATACCCTGCTCTTCCTCTAATTCCCTTCCCCCATCTGACTCTATTATCAACTAAATGCATTCCAGGCAAACAGATGGACACTCACA
GCCCTTCCCAGCCCCACCTCCAAGTAGTATGCAAATGGCACTGAGATTTAGCAAAAACGCGGCGTCTTTGAAAGTTAACAGACACTAAGG
TAGCAGTGCCTGTGTGTTGGAGCTCAGTTAGGAGTTGAAGTTTTCTGCACCTGTGATAACAAGCCCACCAGCCACATGCATTTCTTCTTC
CTGCCACTGTGACTCGGTGGCTGTAGAGCCACATGGCATTTGTCAGCCAATCTGTTTCAAGTCTTTTCTTTCCACCAATAGCTTTCTTAC
AGATTTTCTTGGCTAAATGAGGCCATTACCTAGATTGTCCCTTCAGTAGGAGCCTGAATCCTTCGCTTACCAGGCTGAGAGCTATTTGCC
ATGATAATGCTGATTCTCTCACTCCTCATGCAGAATGTGCACCTGCAGCCCTTTGATGCGTTTTGATTTGGGGGCGATTTTTCAGGCTTT
GATTAGCAGGCTGCTTGCAATGCAGAAGATCACAGTTCCTTTCTGGGGCAGCAGCAACCAGAGCCTCTTCCTGTGTCCTGTGTGTCTGGT
ATGTTTACACCTTGCTCTGAGTTTTTCTCTTGTTTTCTTTTTTTAATTAAGTTTACATTTTAGTTTCTTTGACATCTTGTTTACAGTTTT
TGTCTGATGTTTTTTCTTTTGTAGTGTCTTATGCCCTAGATTTAGTCATCTTGTTAAATATATTTGGATATGAAATCTTGACGAAAAGAA
AATAACTCCTGAAAAAGAGGGTCTATCTTGCCACACGTTAAAAACAAAAATAATGTCCTTGTGGCCTCTTACTTGATAAAGTTGCACCAG
GACGGTCTGAGAAAGGCAGGCGGTGTAATATGTGGTGCAATCCATTTTTTCAAGGTGATGACGGCACAAAATACTTAGACTAGATGCTGA
TCCATAAACATTCACTGATATTCTTACAGGTTGGTTTGCAGTGTTAACATTTTTGTTAGCCTGATCTGTAGGTGGGAAGTAAGATCATCA
TAATTCCTTAGCTCTGAGCACTGATTCAAAATTGTATAAATGACTGAACAACTTAGATGATTTGAAATTAATTGAAAATAAGAAGGGCTT
GTGGAATTTGCATTTGGCTTTGGCCTTCAAGCATTTGGAAATATTAAGAGAATTTCCATTTTACATGTCTCCAACTGGGGTGCTTCTTAC
AACCCTTTCACTTTTTTTTTGAGACGAGTTTCGCTCTGTTGCCCAGGCTGGAGTGCAGTGGCACGATCTCGGCTCACTGCATCCTCTGCC
TCCTGGGTTCAAGTGATTGTCCCGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGTGTGCACTACCATGCCCAGCTAATTTTTGTGTTTT
TAGTAGAGACTGGGTTTCACCATGTTGGCCAGGCTCGTCTCAAACTCCTGACCTCAGGTGATCTACCCGCCTCCACCTCCCAAAGTGTTG
TGATTACAGGCGTGAGCCACCACACCCAGCCCTTTCACTAATTTTTGGCAGAGTTCACAATCCCATCCTATGTCAGAAACTTGAACCTAA
CTTAAGAAATTTTGAGTCATTTTTTTGGAGGACTGAGGCTTTGTTCTACCTACTCTTGAAGAATCCTGATGAAATATTCAAACACATAAA
GGGATGGCCCTGGAGGTCTATCCTGCATACCTGGAGAGCTTCTCTGGTCCTGCCCACCTTGAAAGTTGCAGACTTTGTTGTAACATCTAT
GTGATGAGCTTCCCTGTGAAGCCCCATTTGACAGGTGGGCCAGCAGTGTTTTATCAGCACTCTGATGGCCCACATTTCCCAGGAAAACTT
CTTGAAACTTACCGTTGTGGGCAGTGGTCAGAGCGTGTAGTTCTTATGACTGTCTTGTTTCATCTGTGGAGCACGTGTGGAGCACGTTGG
TACAGCAGTTTCTGTGGGGTTTGGCATGGGTGATTTTGGTTAGTAACCATCCTCCAATTGTTGCTTGTGAAAGTCATTCATAACTTGTTC
CTTTTACTTAGTTTTGTTGTTACTGCTGTTGTTGTTGGTTTGGTTGGTTTTGAGACCGGGTCTGGCTCTGTAGCCCAAGCTGGAATGCGG
TGGCGCGATCATGGCTCCCTGCAGCCTCAAACTCCTGGGCTCAAGCAATCCTCCTGCCTCAGCCTCCCAAGCAGCTGGGAAGATAGGCAC
GTGCCACCACACCCGGCTAATTTTTTCTTTATTTTTTTTGTAGAGATGGGGGTCTCACTATGTTGCCCAGGCTGGTCTCAAACTCCTGGG
CTCAAGCGATCCTTTGGCCTCGGCCTCCCAAAGTGCATGAGCCACCATGCCTGGCCTGTTTAGTTTTGTTTCAAGTTGAAATACCTTTCT
TGTGTTTTCTAATTAGAAAAGTAATATCTACTCATTGTAAAAACTCAAACAGTGCAGAAATGTAGAAAGTAGAAAGTGTAAGTCCCTGGT
TGTCCCTTCTGCCTGAGACAACCACTGCTCACAGTTTGATGTATATCCTTCCAGAGACTCTCAAATTTAAGCAAATAATTTTTATTACCA
TGTCTTTTTATTTGAAGACGTACATTTGCCTCCAAAGTTCAACACAAGTTCAACTGACCATATCCTTCCATGACCTGAATAGATGCTATC
CTTTATCACGATGTTCAATTGCCTTTGAAAGAGAGTAGTCCAGGTATATTCCTGATCAAAATTTGGCATTTTTGATGATACTACTCTACA
CAGATCAGACTCATGTGCAGAATCGTGCCTGGAGAGAGAGGTTTGGTTAAGACAGAGATTTCTGGAAACATTCAAATTGCAAATGGAAAC
TTGAAACCCACAATCTAATGAGGAATGTACTGGAAAAATAATCTGAAGAGTTGACAAATTGTGTACTAGATTGAACACATGGAATGCAAT
GCAATGAGACTTTCTGCACTAAAACTTATCCTCATATGTACAACAATGATGTGTGTATTATATAACAGTGATGTGTACATTTCTGACACC
CCATACATAATATACACAGTTTGTATAAATGCATACATTTAAAAATATATATGTACAATACAGCTAACATAAAACTGTAGTACGCCTGAA
GGATATTACTAGTGCCTAATATTGAGTATGAGTCACTGCGTGTTCGCATCAACTTGGAAGTGCAGTAATTGTTATAAAATTAATCAGTGC
AGCCAACATTATTTATGAATCACATCTTTGAAACTGTGCAGTAGCATATACATATATATTTTTAAATAACATTTTTCACAGTTTTCCAGA
GTTACTGTTGAAATCTGCATCACCAAAAAAAAAAAAAAGCAAGATTTTTTTAACAATGTAGACACTCTTCAGACCCAGTAATCTGCGTGT
GATTTCCTATTTGTAGATTCCCAAGAGACTTTAGCAGTCACCAGCCTTAATGCATGTACAGGATATTATTGTGACTTAATTTATCTGCAG
TTTTTAATCCATGTGAAATTGGAATTTATAAACGGACTTGGATTAAACATGTCTGCCTTTCTAAGGTTGCAAATGTTACATTAAATGATT

>In-frame_REV1_ENST00000393445_chr2_100065798_-_AFF3_ENST00000409579_chr2_100185377_-_1633nt
GGGAGCGTGGACCGCGGCGCTGCTCAGCGGTGGGGCTGCCTTCCCCCGGCCCTCCTCCCTGGTCCCTGGCGAGGGCACTGGCGGCGGCGG
GGCCGGGGTCCGCAAGGCCGGAGAAGGCCGCCGGGCCCGGGCATGGTGGTCTGGGGCAACGCGGAAGAAGCTCCACCATGAGGCGAGGTG
GATGGAGGAAGCGAGCTGAAAATGATGGCTGGGAAACATGGGGTGGGTATATGGCTGCCAAGGTCCAGAAATTGGAGGAACAGTTTCGAT
CAGATGCTGCTATGCAGAAGGATGGGACTTCATCTACAATTTTTAGTGGAGTTGCCATCTATGTTAATGGATACACAGATCCTTCCGCTG
AGGAATTGAGAAAACTAATGATGTTGCATGGAGGTCAATACCATGTATATTATTCCAGATCTAAAACAACACATATTATTGCCACAAATC
TTCCCAATGCCAAAATTAAAGAATTAAAGGGGGAAAAAGTAATTCGACCAGAATGGATTGTGGAAAGGCCTCGCAGTGCCGATTATTTTA
TGCAAGAAGCTAAACGAATGAAGCATAAAGCAGATGCAATGGTGGAAAAGTTTGGAAAGGCTTTGAACTATGCTGAAGCAGCATTGTCGT
TTATCGAGTGTGGAAATGCAATGGAACAAGGCCCCATGGAATCCAAATCTCCTTATACGATGTATTCAGAAACAGTAGAGCTCATCAGGT
ATGCTATGAGACTAAAAACCCACTCAGGCCCCAATGCCACACCAGAAGACAAACAACTGGCTGCATTATGTTACCGATGCCTGGCCCTCC
TGTACTGGCGGATGTTTCGACTCAAAAGGGACCACGCTGTAAAGTATTCAAAAGCACTAATCGACTATTTCAAGAACTCATCTAAAGCCG
CCCAAGCCCCATCTCCGTGGGGGGCCAGTGGAAAGAGCACTGGAACCCCATCCCCCATGTCTCCCAACCCCTCTCCCGCCAGCTCCGTGG
GGTCTCAGGGCAGCCTCTCCAACGCCAGCGCCCTGTCCCCGTCGACCATCGTCAGCATCCCACAGCGCATCCACCAGATGGCGGCCAACC
ACGTCAGCATCACCAACAGCATCCTGCACAGCTACGACTACTGGGAGATGGCCGACAACCTGGCCAAGGAAAACCGAGAATTCTTCAACG
ACCTGGATCTGCTCATGGGGCCGGTCACCCTGCACAGCAGCATGGAGCACCTGGTCCAGTACTCCCAACAGGGCCTGCACTGGCTGCGGA
ACAGCGCCCACCTGTCATAGGGACCTCACCCTGGGGCCAGAGTGGGCTCTGGTCTCCACAGATGGCTCAACGTTTTTGGACACTGTGCTA
CTGAAACTCCCAGCCACAGCATTTATCAGACTGCGGTGAACATTTCCTCAGCATTGAACAATGATCTTTTGCAGGGCATGTGTGTTTGTA
TGTGTGGGTATATAAGAAGCCGCCTGTGTATGTGTGTAAGATACACAGCTCTTCAGAACACACCTTCTTTGTCTAGTTTCCATAATCCCA
GGCTAGACAAAGTGATCAGAGGTTTCTGACTAGAGGAAGTACACACACACACACACACACACACACACACCGTACACTCACACACAATCA

>In-frame_REV1_ENST00000258428_chr2_100065798_-_AFF3_ENST00000409236_chr2_100185377_-_6955nt
CGGAGGGGGAGGGGCGGAGAGCCACCGCGGAGCGCGCGCGGGGTTGGTTGCCGCGAGCGTGGGGGAGCGTGGACCGCGGCGCTGCTCAGC
GGTGGGGCTGCCTTCCCCCGGCCCTCCTCCCTGGTCCCTGGCGAGGGCACTGGCGGCGGCGGGGCCGGGGTCCGCAAGGCCGGAGAAGGC
CGCCGGGCCCGGGCATGGTGGTCTGGGGCAACGCGGAAGAAGCTCCACCATGAGGCGAGGTGGATGGAGGAAGCGAGCTGAAAATGATGG
CTGGGAAACATGGGGTGGGTATATGGCTGCCAAGGTCCAGAAATTGGAGGAACAGTTTCGATCAGATGCTGCTATGCAGAAGGATGGGAC
TTCATCTACAATTTTTAGTGGAGTTGCCATCTATGTTAATGGATACACAGATCCTTCCGCTGAGGAATTGAGAAAACTAATGATGTTGCA
TGGAGGTCAATACCATGTATATTATTCCAGATCTAAAACAACACATATTATTGCCACAAATCTTCCCAATGCCAAAATTAAAGAATTAAA
GGGGGAAAAAGTAATTCGACCAGAATGGATTGTGGAAAGGCCTCGCAGTGCCGATTATTTTATGCAAGAAGCTAAACGAATGAAGCATAA
AGCAGATGCAATGGTGGAAAAGTTTGGAAAGGCTTTGAACTATGCTGAAGCAGCATTGTCGTTTATCGAGTGTGGAAATGCAATGGAACA
AGGCCCCATGGAATCCAAATCTCCTTATACGATGTATTCAGAAACAGTAGAGCTCATCAGGTATGCTATGAGACTAAAAACCCACTCAGG
CCCCAATGCCACACCAGAAGACAAACAACTGGCTGCATTATGTTACCGATGCCTGGCCCTCCTGTACTGGCGGATGTTTCGACTCAAAAG
GGACCACGCTGTAAAGTATTCAAAAGCACTAATCGACTATTTCAAGAACTCATCTAAAGCCGCCCAAGCCCCATCTCCGTGGGGGGCCAG
TGGAAAGAGCACTGGAACCCCATCCCCCATGTCTCCCAACCCCTCTCCCGCCAGCTCCGTGGGGTCTCAGGGCAGCCTCTCCAACGCCAG
CGCCCTGTCCCCGTCGACCATCGTCAGCATCCCACAGCGCATCCACCAGATGGCGGCCAACCACGTCAGCATCACCAACAGCATCCTGCA
CAGCTACGACTACTGGGAGATGGCCGACAACCTGGCCAAGGAAAACCGAGAATTCTTCAACGACCTGGATCTGCTCATGGGGCCGGTCAC
CCTGCACAGCAGCATGGAGCACCTGGTCCAGTACTCCCAACAGGGCCTGCACTGGCTGCGGAACAGCGCCCACCTGTCATAGGGACCTCA
CCCTGGGGCCAGAGTGGGCTCTGGTCTCCACAGATGGCTCAACGTTTTTGGACACTGTGCTACTGAAACTCCCAGCCACAGCATTTATCA
GACTGCGGTGAACATTTCCTCAGCATTGAACAATGATCTTTTGCAGGGCATGTGTGTTTGTATGTGTGGGTATATAAGAAGCCGCCTGTG
TATGTGTGTAAGATACACAGCTCTTCAGAACACACCTTCTTTGTCTAGTTTCCATAATCCCAGGCTAGACAAAGTGATCAGAGGTTTCTG
ACTAGAGGAAGTACACACACACACACACACACACACACACACCGTACACTCACACACAATCACAGACACACACTTTCTATTCCATTCCAG
TGCTAAACCGTGACTTCTTAGAAAATTCAACCAAAATCTCATGGGTTAGTTAACCAGGTGCAATACAGCACACCAAAAGCTTGACTGCCA
GTGAAGATGGACCTGCTCTTATACTGTTGATTACTTTCAGTATTAATATACTATTCCCCAATTATTTTTTGATTGGTATGTATTAATGGG
TAATTGAATAATGAAAATAAGCCAGGTATTTTTGTGCCGGAAGTTTACTAGATTGCATGTTACCAAATACCCTGCTCTTCCTCTAATTCC
CTTCCCCCATCTGACTCTATTATCAACTAAATGCATTCCAGGCAAACAGATGGACACTCACAGCCCTTCCCAGCCCCACCTCCAAGTAGT
ATGCAAATGGCACTGAGATTTAGCAAAAACGCGGCGTCTTTGAAAGTTAACAGACACTAAGGTAGCAGTGCCTGTGTGTTGGAGCTCAGT
TAGGAGTTGAAGTTTTCTGCACCTGTGATAACAAGCCCACCAGCCACATGCATTTCTTCTTCCTGCCACTGTGACTCGGTGGCTGTAGAG
CCACATGGCATTTGTCAGCCAATCTGTTTCAAGTCTTTTCTTTCCACCAATAGCTTTCTTACAGATTTTCTTGGCTAAATGAGGCCATTA
CCTAGATTGTCCCTTCAGTAGGAGCCTGAATCCTTCGCTTACCAGGCTGAGAGCTATTTGCCATGATAATGCTGATTCTCTCACTCCTCA
TGCAGAATGTGCACCTGCAGCCCTTTGATGCGTTTTGATTTGGGGGCGATTTTTCAGGCTTTGATTAGCAGGCTGCTTGCAATGCAGAAG
ATCACAGTTCCTTTCTGGGGCAGCAGCAACCAGAGCCTCTTCCTGTGTCCTGTGTGTCTGGTATGTTTACACCTTGCTCTGAGTTTTTCT
CTTGTTTTCTTTTTTTAATTAAGTTTACATTTTAGTTTCTTTGACATCTTGTTTACAGTTTTTGTCTGATGTTTTTTCTTTTGTAGTGTC
TTATGCCCTAGATTTAGTCATCTTGTTAAATATATTTGGATATGAAATCTTGACGAAAAGAAAATAACTCCTGAAAAAGAGGGTCTATCT
TGCCACACGTTAAAAACAAAAATAATGTCCTTGTGGCCTCTTACTTGATAAAGTTGCACCAGGACGGTCTGAGAAAGGCAGGCGGTGTAA
TATGTGGTGCAATCCATTTTTTCAAGGTGATGACGGCACAAAATACTTAGACTAGATGCTGATCCATAAACATTCACTGATATTCTTACA
GGTTGGTTTGCAGTGTTAACATTTTTGTTAGCCTGATCTGTAGGTGGGAAGTAAGATCATCATAATTCCTTAGCTCTGAGCACTGATTCA
AAATTGTATAAATGACTGAACAACTTAGATGATTTGAAATTAATTGAAAATAAGAAGGGCTTGTGGAATTTGCATTTGGCTTTGGCCTTC
AAGCATTTGGAAATATTAAGAGAATTTCCATTTTACATGTCTCCAACTGGGGTGCTTCTTACAACCCTTTCACTTTTTTTTTGAGACGAG
TTTCGCTCTGTTGCCCAGGCTGGAGTGCAGTGGCACGATCTCGGCTCACTGCATCCTCTGCCTCCTGGGTTCAAGTGATTGTCCCGCCTC
AGCCTCCCAAGTAGCTGGGATTACAGGTGTGCACTACCATGCCCAGCTAATTTTTGTGTTTTTAGTAGAGACTGGGTTTCACCATGTTGG
CCAGGCTCGTCTCAAACTCCTGACCTCAGGTGATCTACCCGCCTCCACCTCCCAAAGTGTTGTGATTACAGGCGTGAGCCACCACACCCA
GCCCTTTCACTAATTTTTGGCAGAGTTCACAATCCCATCCTATGTCAGAAACTTGAACCTAACTTAAGAAATTTTGAGTCATTTTTTTGG
AGGACTGAGGCTTTGTTCTACCTACTCTTGAAGAATCCTGATGAAATATTCAAACACATAAAGGGATGGCCCTGGAGGTCTATCCTGCAT
ACCTGGAGAGCTTCTCTGGTCCTGCCCACCTTGAAAGTTGCAGACTTTGTTGTAACATCTATGTGATGAGCTTCCCTGTGAAGCCCCATT
TGACAGGTGGGCCAGCAGTGTTTTATCAGCACTCTGATGGCCCACATTTCCCAGGAAAACTTCTTGAAACTTACCGTTGTGGGCAGTGGT
CAGAGCGTGTAGTTCTTATGACTGTCTTGTTTCATCTGTGGAGCACGTGTGGAGCACGTTGGTACAGCAGTTTCTGTGGGGTTTGGCATG
GGTGATTTTGGTTAGTAACCATCCTCCAATTGTTGCTTGTGAAAGTCATTCATAACTTGTTCCTTTTACTTAGTTTTGTTGTTACTGCTG
TTGTTGTTGGTTTGGTTGGTTTTGAGACCGGGTCTGGCTCTGTAGCCCAAGCTGGAATGCGGTGGCGCGATCATGGCTCCCTGCAGCCTC
AAACTCCTGGGCTCAAGCAATCCTCCTGCCTCAGCCTCCCAAGCAGCTGGGAAGATAGGCACGTGCCACCACACCCGGCTAATTTTTTCT
TTATTTTTTTTGTAGAGATGGGGGTCTCACTATGTTGCCCAGGCTGGTCTCAAACTCCTGGGCTCAAGCGATCCTTTGGCCTCGGCCTCC
CAAAGTGCATGAGCCACCATGCCTGGCCTGTTTAGTTTTGTTTCAAGTTGAAATACCTTTCTTGTGTTTTCTAATTAGAAAAGTAATATC
TACTCATTGTAAAAACTCAAACAGTGCAGAAATGTAGAAAGTAGAAAGTGTAAGTCCCTGGTTGTCCCTTCTGCCTGAGACAACCACTGC
TCACAGTTTGATGTATATCCTTCCAGAGACTCTCAAATTTAAGCAAATAATTTTTATTACCATGTCTTTTTATTTGAAGACGTACATTTG
CCTCCAAAGTTCAACACAAGTTCAACTGACCATATCCTTCCATGACCTGAATAGATGCTATCCTTTATCACGATGTTCAATTGCCTTTGA
AAGAGAGTAGTCCAGGTATATTCCTGATCAAAATTTGGCATTTTTGATGATACTACTCTACACAGATCAGACTCATGTGCAGAATCGTGC
CTGGAGAGAGAGGTTTGGTTAAGACAGAGATTTCTGGAAACATTCAAATTGCAAATGGAAACTTGAAACCCACAATCTAATGAGGAATGT
ACTGGAAAAATAATCTGAAGAGTTGACAAATTGTGTACTAGATTGAACACATGGAATGCAATGCAATGAGACTTTCTGCACTAAAACTTA
TCCTCATATGTACAACAATGATGTGTGTATTATATAACAGTGATGTGTACATTTCTGACACCCCATACATAATATACACAGTTTGTATAA
ATGCATACATTTAAAAATATATATGTACAATACAGCTAACATAAAACTGTAGTACGCCTGAAGGATATTACTAGTGCCTAATATTGAGTA
TGAGTCACTGCGTGTTCGCATCAACTTGGAAGTGCAGTAATTGTTATAAAATTAATCAGTGCAGCCAACATTATTTATGAATCACATCTT
TGAAACTGTGCAGTAGCATATACATATATATTTTTAAATAACATTTTTCACAGTTTTCCAGAGTTACTGTTGAAATCTGCATCACCAAAA
AAAAAAAAAAGCAAGATTTTTTTAACAATGTAGACACTCTTCAGACCCAGTAATCTGCGTGTGATTTCCTATTTGTAGATTCCCAAGAGA
CTTTAGCAGTCACCAGCCTTAATGCATGTACAGGATATTATTGTGACTTAATTTATCTGCAGTTTTTAATCCATGTGAAATTGGAATTTA
TAAACGGACTTGGATTAAACATGTCTGCCTTTCTAAGGTTGCAAATGTTACATTAAATGATTTATGTTGTAAATGAGAGAAGTTGAGTTG
TACGTAAAAGACATCCACCAATTTCTGTGAATATTTTTACACGGAAACTTGAGAATCAAAATACGTTCAAGTCAGTTGTTCTGGCTCCCA
GTTTATAATCTCGAAAAGCAATCTTTTTGTTTCATAAATGGCTTAAATGTAGCTCCCACAGATTATCAGTATGAAGTCTGACATTTTTCA
TGGAAAAGAAGTATGTTTTTCTTCATTATAACTATAGTTTACTATTTGTCTTTGCTATTTCCTGATACATACACATACGCACACACGCGC
GCACATGCATGCACGTATGCACATGCACGCTCCCAGTGTCCCAGTGAAGGCTCAACAGGAAGCTTGAGAAGGTCATCTCAATGGCCACAG
GGTTCCTGTTCAACCAGTAGCCCTGGGATGCCGCTTTGCTTGTCATTCTTTAGTGTCACAAGTTAGTTCCCTGACTTGTGTGCAGTCAGG
GAACTGCACACAACTGAAACCAACATGGTGGAATCATGTTTGCAATATTTGGTTGAGTAAAATAAGATAATTTTGAACTAAAGAAGACGG
AGGCATTAGACCAGTGGCTTGACATGAAGCATCCCCTATGTGGGAGGGTAAGTTTGTTAACTTCATTTTTAGTCTTATCTCCAACCCTTT
TCCTTATCCTCCTCCCCAAACTAAAGAAGCAGAAACAGCAACAAAAGCAAAACCATCCCTTCACCTGATCCAGCCCATGTCCTTAGATTC
AAATATCCTTTGTCTTTTTCCCATTATACCATCTGACATAACTCACTCGTGTCTAGAGAGAAAAATGCAGAAAGGGTTTGTTTGCAGATG
GGCAGTTCAGTTGAGTCCTCATTAACCAGGCAGAGGGGTGCAGAAGAAGCCTGACTCAGGGTCACCATGGAGAACTCCTCATCCCAGAGA
TGGGTGGGACAGGAACTTGGCTTTGCTTCACCAACCACTGAGCTTGATACTCTTTCAGAGGTGGTTTGTGCTAAGAAACACCCAGCAGTC
TTTCAAGAACGTTCTCTTCTGTAGCTTTGCCTGCTACACAGCTGAAGTCTGTCCCTATAAGAATTATATTTGTAAAAAGTAATACATTTT
CGAAGAAACCCGGATCAAGTGGAATCTTGAAAGTTTTTTTAATGAAAGGGGAAAAACAACCTGACCACATAAACTGCACTTCCAACCATT
TGGAACCAGAGTTTATGTCCTCATTTTCCCATTCTCAGAAGAGCACAGTTTTTCAATATTACAACTTCCTGGCAAATAGCACAAGAAATG
TTCAGACTTGAGATTTGTGTTCCCTTTGTCCAGATTATTCTGTATATGTCACCAAAGGGGTTAACTTGTTTGCTTGGCATGAGGAAAATT

>In-frame_REV1_ENST00000258428_chr2_100065798_-_AFF3_ENST00000356421_chr2_100185377_-_5560nt
CGGAGGGGGAGGGGCGGAGAGCCACCGCGGAGCGCGCGCGGGGTTGGTTGCCGCGAGCGTGGGGGAGCGTGGACCGCGGCGCTGCTCAGC
GGTGGGGCTGCCTTCCCCCGGCCCTCCTCCCTGGTCCCTGGCGAGGGCACTGGCGGCGGCGGGGCCGGGGTCCGCAAGGCCGGAGAAGGC
CGCCGGGCCCGGGCATGGTGGTCTGGGGCAACGCGGAAGAAGCTCCACCATGAGGCGAGGTGGATGGAGGAAGCGAGCTGAAAATGATGG
CTGGGAAACATGGGGTGGGTATATGGCTGCCAAGGTCCAGAAATTGGAGGAACAGTTTCGATCAGATGCTGCTATGCAGAAGGATGGGAC
TTCATCTACAATTTTTAGTGGAGTTGCCATCTATGTTAATGGATACACAGATCCTTCCGCTGAGGAATTGAGAAAACTAATGATGTTGCA
TGGAGGTCAATACCATGTATATTATTCCAGATCTAAAACAACACATATTATTGCCACAAATCTTCCCAATGCCAAAATTAAAGAATTAAA
GGGGGAAAAAGTAATTCGACCAGAATGGATTGTGGAAAGGCCTCGCAGTGCCGATTATTTTATGCAAGAAGCTAAACGAATGAAGCATAA
AGCAGATGCAATGGTGGAAAAGTTTGGAAAGGCTTTGAACTATGCTGAAGCAGCATTGTCGTTTATCGAGTGTGGAAATGCAATGGAACA
AGGCCCCATGGAATCCAAATCTCCTTATACGATGTATTCAGAAACAGTAGAGCTCATCAGGTATGCTATGAGACTAAAAACCCACTCAGG
CCCCAATGCCACACCAGAAGACAAACAACTGGCTGCATTATGTTACCGATGCCTGGCCCTCCTGTACTGGCGGATGTTTCGACTCAAAAG
GGACCACGCTGTAAAGTATTCAAAAGCACTAATCGACTATTTCAAGAACTCATCTAAAGCCGCCCAAGCCCCATCTCCGTGGGGGGCCAG
TGGAAAGAGCACTGGAACCCCATCCCCCATGTCTCCCAACCCCTCTCCCGCCAGCTCCGTGGGGTCTCAGGGCAGCCTCTCCAACGCCAG
CGCCCTGTCCCCGTCGACCATCGTCAGCATCCCACAGCGCATCCACCAGATGGCGGCCAACCACGTCAGCATCACCAACAGCATCCTGCA
CAGCTACGACTACTGGGAGATGGCCGACAACCTGGCCAAGGAAAACCGAGAATTCTTCAACGACCTGGATCTGCTCATGGGGCCGGTCAC
CCTGCACAGCAGCATGGAGCACCTGGTCCAGTACTCCCAACAGGGCCTGCACTGGCTGCGGAACAGCGCCCACCTGTCATAGGGACCTCA
CCCTGGGGCCAGAGTGGGCTCTGGTCTCCACAGATGGCTCAACGTTTTTGGACACTGTGCTACTGAAACTCCCAGCCACAGCATTTATCA
GACTGCGGTGAACATTTCCTCAGCATTGAACAATGATCTTTTGCAGGGCATGTGTGTTTGTATGTGTGGGTATATAAGAAGCCGCCTGTG
TATGTGTGTAAGATACACAGCTCTTCAGAACACACCTTCTTTGTCTAGTTTCCATAATCCCAGGCTAGACAAAGTGATCAGAGGTTTCTG
ACTAGAGGAAGTACACACACACACACACACACACACACACACCGTACACTCACACACAATCACAGACACACACTTTCTATTCCATTCCAG
TGCTAAACCGTGACTTCTTAGAAAATTCAACCAAAATCTCATGGGTTAGTTAACCAGGTGCAATACAGCACACCAAAAGCTTGACTGCCA
GTGAAGATGGACCTGCTCTTATACTGTTGATTACTTTCAGTATTAATATACTATTCCCCAATTATTTTTTGATTGGTATGTATTAATGGG
TAATTGAATAATGAAAATAAGCCAGGTATTTTTGTGCCGGAAGTTTACTAGATTGCATGTTACCAAATACCCTGCTCTTCCTCTAATTCC
CTTCCCCCATCTGACTCTATTATCAACTAAATGCATTCCAGGCAAACAGATGGACACTCACAGCCCTTCCCAGCCCCACCTCCAAGTAGT
ATGCAAATGGCACTGAGATTTAGCAAAAACGCGGCGTCTTTGAAAGTTAACAGACACTAAGGTAGCAGTGCCTGTGTGTTGGAGCTCAGT
TAGGAGTTGAAGTTTTCTGCACCTGTGATAACAAGCCCACCAGCCACATGCATTTCTTCTTCCTGCCACTGTGACTCGGTGGCTGTAGAG
CCACATGGCATTTGTCAGCCAATCTGTTTCAAGTCTTTTCTTTCCACCAATAGCTTTCTTACAGATTTTCTTGGCTAAATGAGGCCATTA
CCTAGATTGTCCCTTCAGTAGGAGCCTGAATCCTTCGCTTACCAGGCTGAGAGCTATTTGCCATGATAATGCTGATTCTCTCACTCCTCA
TGCAGAATGTGCACCTGCAGCCCTTTGATGCGTTTTGATTTGGGGGCGATTTTTCAGGCTTTGATTAGCAGGCTGCTTGCAATGCAGAAG
ATCACAGTTCCTTTCTGGGGCAGCAGCAACCAGAGCCTCTTCCTGTGTCCTGTGTGTCTGGTATGTTTACACCTTGCTCTGAGTTTTTCT
CTTGTTTTCTTTTTTTAATTAAGTTTACATTTTAGTTTCTTTGACATCTTGTTTACAGTTTTTGTCTGATGTTTTTTCTTTTGTAGTGTC
TTATGCCCTAGATTTAGTCATCTTGTTAAATATATTTGGATATGAAATCTTGACGAAAAGAAAATAACTCCTGAAAAAGAGGGTCTATCT
TGCCACACGTTAAAAACAAAAATAATGTCCTTGTGGCCTCTTACTTGATAAAGTTGCACCAGGACGGTCTGAGAAAGGCAGGCGGTGTAA
TATGTGGTGCAATCCATTTTTTCAAGGTGATGACGGCACAAAATACTTAGACTAGATGCTGATCCATAAACATTCACTGATATTCTTACA
GGTTGGTTTGCAGTGTTAACATTTTTGTTAGCCTGATCTGTAGGTGGGAAGTAAGATCATCATAATTCCTTAGCTCTGAGCACTGATTCA
AAATTGTATAAATGACTGAACAACTTAGATGATTTGAAATTAATTGAAAATAAGAAGGGCTTGTGGAATTTGCATTTGGCTTTGGCCTTC
AAGCATTTGGAAATATTAAGAGAATTTCCATTTTACATGTCTCCAACTGGGGTGCTTCTTACAACCCTTTCACTTTTTTTTTGAGACGAG
TTTCGCTCTGTTGCCCAGGCTGGAGTGCAGTGGCACGATCTCGGCTCACTGCATCCTCTGCCTCCTGGGTTCAAGTGATTGTCCCGCCTC
AGCCTCCCAAGTAGCTGGGATTACAGGTGTGCACTACCATGCCCAGCTAATTTTTGTGTTTTTAGTAGAGACTGGGTTTCACCATGTTGG
CCAGGCTCGTCTCAAACTCCTGACCTCAGGTGATCTACCCGCCTCCACCTCCCAAAGTGTTGTGATTACAGGCGTGAGCCACCACACCCA
GCCCTTTCACTAATTTTTGGCAGAGTTCACAATCCCATCCTATGTCAGAAACTTGAACCTAACTTAAGAAATTTTGAGTCATTTTTTTGG
AGGACTGAGGCTTTGTTCTACCTACTCTTGAAGAATCCTGATGAAATATTCAAACACATAAAGGGATGGCCCTGGAGGTCTATCCTGCAT
ACCTGGAGAGCTTCTCTGGTCCTGCCCACCTTGAAAGTTGCAGACTTTGTTGTAACATCTATGTGATGAGCTTCCCTGTGAAGCCCCATT
TGACAGGTGGGCCAGCAGTGTTTTATCAGCACTCTGATGGCCCACATTTCCCAGGAAAACTTCTTGAAACTTACCGTTGTGGGCAGTGGT
CAGAGCGTGTAGTTCTTATGACTGTCTTGTTTCATCTGTGGAGCACGTGTGGAGCACGTTGGTACAGCAGTTTCTGTGGGGTTTGGCATG
GGTGATTTTGGTTAGTAACCATCCTCCAATTGTTGCTTGTGAAAGTCATTCATAACTTGTTCCTTTTACTTAGTTTTGTTGTTACTGCTG
TTGTTGTTGGTTTGGTTGGTTTTGAGACCGGGTCTGGCTCTGTAGCCCAAGCTGGAATGCGGTGGCGCGATCATGGCTCCCTGCAGCCTC
AAACTCCTGGGCTCAAGCAATCCTCCTGCCTCAGCCTCCCAAGCAGCTGGGAAGATAGGCACGTGCCACCACACCCGGCTAATTTTTTCT
TTATTTTTTTTGTAGAGATGGGGGTCTCACTATGTTGCCCAGGCTGGTCTCAAACTCCTGGGCTCAAGCGATCCTTTGGCCTCGGCCTCC
CAAAGTGCATGAGCCACCATGCCTGGCCTGTTTAGTTTTGTTTCAAGTTGAAATACCTTTCTTGTGTTTTCTAATTAGAAAAGTAATATC
TACTCATTGTAAAAACTCAAACAGTGCAGAAATGTAGAAAGTAGAAAGTGTAAGTCCCTGGTTGTCCCTTCTGCCTGAGACAACCACTGC
TCACAGTTTGATGTATATCCTTCCAGAGACTCTCAAATTTAAGCAAATAATTTTTATTACCATGTCTTTTTATTTGAAGACGTACATTTG
CCTCCAAAGTTCAACACAAGTTCAACTGACCATATCCTTCCATGACCTGAATAGATGCTATCCTTTATCACGATGTTCAATTGCCTTTGA
AAGAGAGTAGTCCAGGTATATTCCTGATCAAAATTTGGCATTTTTGATGATACTACTCTACACAGATCAGACTCATGTGCAGAATCGTGC
CTGGAGAGAGAGGTTTGGTTAAGACAGAGATTTCTGGAAACATTCAAATTGCAAATGGAAACTTGAAACCCACAATCTAATGAGGAATGT
ACTGGAAAAATAATCTGAAGAGTTGACAAATTGTGTACTAGATTGAACACATGGAATGCAATGCAATGAGACTTTCTGCACTAAAACTTA
TCCTCATATGTACAACAATGATGTGTGTATTATATAACAGTGATGTGTACATTTCTGACACCCCATACATAATATACACAGTTTGTATAA
ATGCATACATTTAAAAATATATATGTACAATACAGCTAACATAAAACTGTAGTACGCCTGAAGGATATTACTAGTGCCTAATATTGAGTA
TGAGTCACTGCGTGTTCGCATCAACTTGGAAGTGCAGTAATTGTTATAAAATTAATCAGTGCAGCCAACATTATTTATGAATCACATCTT
TGAAACTGTGCAGTAGCATATACATATATATTTTTAAATAACATTTTTCACAGTTTTCCAGAGTTACTGTTGAAATCTGCATCACCAAAA
AAAAAAAAAAGCAAGATTTTTTTAACAATGTAGACACTCTTCAGACCCAGTAATCTGCGTGTGATTTCCTATTTGTAGATTCCCAAGAGA
CTTTAGCAGTCACCAGCCTTAATGCATGTACAGGATATTATTGTGACTTAATTTATCTGCAGTTTTTAATCCATGTGAAATTGGAATTTA

>In-frame_REV1_ENST00000258428_chr2_100065798_-_AFF3_ENST00000317233_chr2_100185377_-_5560nt
CGGAGGGGGAGGGGCGGAGAGCCACCGCGGAGCGCGCGCGGGGTTGGTTGCCGCGAGCGTGGGGGAGCGTGGACCGCGGCGCTGCTCAGC
GGTGGGGCTGCCTTCCCCCGGCCCTCCTCCCTGGTCCCTGGCGAGGGCACTGGCGGCGGCGGGGCCGGGGTCCGCAAGGCCGGAGAAGGC
CGCCGGGCCCGGGCATGGTGGTCTGGGGCAACGCGGAAGAAGCTCCACCATGAGGCGAGGTGGATGGAGGAAGCGAGCTGAAAATGATGG
CTGGGAAACATGGGGTGGGTATATGGCTGCCAAGGTCCAGAAATTGGAGGAACAGTTTCGATCAGATGCTGCTATGCAGAAGGATGGGAC
TTCATCTACAATTTTTAGTGGAGTTGCCATCTATGTTAATGGATACACAGATCCTTCCGCTGAGGAATTGAGAAAACTAATGATGTTGCA
TGGAGGTCAATACCATGTATATTATTCCAGATCTAAAACAACACATATTATTGCCACAAATCTTCCCAATGCCAAAATTAAAGAATTAAA
GGGGGAAAAAGTAATTCGACCAGAATGGATTGTGGAAAGGCCTCGCAGTGCCGATTATTTTATGCAAGAAGCTAAACGAATGAAGCATAA
AGCAGATGCAATGGTGGAAAAGTTTGGAAAGGCTTTGAACTATGCTGAAGCAGCATTGTCGTTTATCGAGTGTGGAAATGCAATGGAACA
AGGCCCCATGGAATCCAAATCTCCTTATACGATGTATTCAGAAACAGTAGAGCTCATCAGGTATGCTATGAGACTAAAAACCCACTCAGG
CCCCAATGCCACACCAGAAGACAAACAACTGGCTGCATTATGTTACCGATGCCTGGCCCTCCTGTACTGGCGGATGTTTCGACTCAAAAG
GGACCACGCTGTAAAGTATTCAAAAGCACTAATCGACTATTTCAAGAACTCATCTAAAGCCGCCCAAGCCCCATCTCCGTGGGGGGCCAG
TGGAAAGAGCACTGGAACCCCATCCCCCATGTCTCCCAACCCCTCTCCCGCCAGCTCCGTGGGGTCTCAGGGCAGCCTCTCCAACGCCAG
CGCCCTGTCCCCGTCGACCATCGTCAGCATCCCACAGCGCATCCACCAGATGGCGGCCAACCACGTCAGCATCACCAACAGCATCCTGCA
CAGCTACGACTACTGGGAGATGGCCGACAACCTGGCCAAGGAAAACCGAGAATTCTTCAACGACCTGGATCTGCTCATGGGGCCGGTCAC
CCTGCACAGCAGCATGGAGCACCTGGTCCAGTACTCCCAACAGGGCCTGCACTGGCTGCGGAACAGCGCCCACCTGTCATAGGGACCTCA
CCCTGGGGCCAGAGTGGGCTCTGGTCTCCACAGATGGCTCAACGTTTTTGGACACTGTGCTACTGAAACTCCCAGCCACAGCATTTATCA
GACTGCGGTGAACATTTCCTCAGCATTGAACAATGATCTTTTGCAGGGCATGTGTGTTTGTATGTGTGGGTATATAAGAAGCCGCCTGTG
TATGTGTGTAAGATACACAGCTCTTCAGAACACACCTTCTTTGTCTAGTTTCCATAATCCCAGGCTAGACAAAGTGATCAGAGGTTTCTG
ACTAGAGGAAGTACACACACACACACACACACACACACACACCGTACACTCACACACAATCACAGACACACACTTTCTATTCCATTCCAG
TGCTAAACCGTGACTTCTTAGAAAATTCAACCAAAATCTCATGGGTTAGTTAACCAGGTGCAATACAGCACACCAAAAGCTTGACTGCCA
GTGAAGATGGACCTGCTCTTATACTGTTGATTACTTTCAGTATTAATATACTATTCCCCAATTATTTTTTGATTGGTATGTATTAATGGG
TAATTGAATAATGAAAATAAGCCAGGTATTTTTGTGCCGGAAGTTTACTAGATTGCATGTTACCAAATACCCTGCTCTTCCTCTAATTCC
CTTCCCCCATCTGACTCTATTATCAACTAAATGCATTCCAGGCAAACAGATGGACACTCACAGCCCTTCCCAGCCCCACCTCCAAGTAGT
ATGCAAATGGCACTGAGATTTAGCAAAAACGCGGCGTCTTTGAAAGTTAACAGACACTAAGGTAGCAGTGCCTGTGTGTTGGAGCTCAGT
TAGGAGTTGAAGTTTTCTGCACCTGTGATAACAAGCCCACCAGCCACATGCATTTCTTCTTCCTGCCACTGTGACTCGGTGGCTGTAGAG
CCACATGGCATTTGTCAGCCAATCTGTTTCAAGTCTTTTCTTTCCACCAATAGCTTTCTTACAGATTTTCTTGGCTAAATGAGGCCATTA
CCTAGATTGTCCCTTCAGTAGGAGCCTGAATCCTTCGCTTACCAGGCTGAGAGCTATTTGCCATGATAATGCTGATTCTCTCACTCCTCA
TGCAGAATGTGCACCTGCAGCCCTTTGATGCGTTTTGATTTGGGGGCGATTTTTCAGGCTTTGATTAGCAGGCTGCTTGCAATGCAGAAG
ATCACAGTTCCTTTCTGGGGCAGCAGCAACCAGAGCCTCTTCCTGTGTCCTGTGTGTCTGGTATGTTTACACCTTGCTCTGAGTTTTTCT
CTTGTTTTCTTTTTTTAATTAAGTTTACATTTTAGTTTCTTTGACATCTTGTTTACAGTTTTTGTCTGATGTTTTTTCTTTTGTAGTGTC
TTATGCCCTAGATTTAGTCATCTTGTTAAATATATTTGGATATGAAATCTTGACGAAAAGAAAATAACTCCTGAAAAAGAGGGTCTATCT
TGCCACACGTTAAAAACAAAAATAATGTCCTTGTGGCCTCTTACTTGATAAAGTTGCACCAGGACGGTCTGAGAAAGGCAGGCGGTGTAA
TATGTGGTGCAATCCATTTTTTCAAGGTGATGACGGCACAAAATACTTAGACTAGATGCTGATCCATAAACATTCACTGATATTCTTACA
GGTTGGTTTGCAGTGTTAACATTTTTGTTAGCCTGATCTGTAGGTGGGAAGTAAGATCATCATAATTCCTTAGCTCTGAGCACTGATTCA
AAATTGTATAAATGACTGAACAACTTAGATGATTTGAAATTAATTGAAAATAAGAAGGGCTTGTGGAATTTGCATTTGGCTTTGGCCTTC
AAGCATTTGGAAATATTAAGAGAATTTCCATTTTACATGTCTCCAACTGGGGTGCTTCTTACAACCCTTTCACTTTTTTTTTGAGACGAG
TTTCGCTCTGTTGCCCAGGCTGGAGTGCAGTGGCACGATCTCGGCTCACTGCATCCTCTGCCTCCTGGGTTCAAGTGATTGTCCCGCCTC
AGCCTCCCAAGTAGCTGGGATTACAGGTGTGCACTACCATGCCCAGCTAATTTTTGTGTTTTTAGTAGAGACTGGGTTTCACCATGTTGG
CCAGGCTCGTCTCAAACTCCTGACCTCAGGTGATCTACCCGCCTCCACCTCCCAAAGTGTTGTGATTACAGGCGTGAGCCACCACACCCA
GCCCTTTCACTAATTTTTGGCAGAGTTCACAATCCCATCCTATGTCAGAAACTTGAACCTAACTTAAGAAATTTTGAGTCATTTTTTTGG
AGGACTGAGGCTTTGTTCTACCTACTCTTGAAGAATCCTGATGAAATATTCAAACACATAAAGGGATGGCCCTGGAGGTCTATCCTGCAT
ACCTGGAGAGCTTCTCTGGTCCTGCCCACCTTGAAAGTTGCAGACTTTGTTGTAACATCTATGTGATGAGCTTCCCTGTGAAGCCCCATT
TGACAGGTGGGCCAGCAGTGTTTTATCAGCACTCTGATGGCCCACATTTCCCAGGAAAACTTCTTGAAACTTACCGTTGTGGGCAGTGGT
CAGAGCGTGTAGTTCTTATGACTGTCTTGTTTCATCTGTGGAGCACGTGTGGAGCACGTTGGTACAGCAGTTTCTGTGGGGTTTGGCATG
GGTGATTTTGGTTAGTAACCATCCTCCAATTGTTGCTTGTGAAAGTCATTCATAACTTGTTCCTTTTACTTAGTTTTGTTGTTACTGCTG
TTGTTGTTGGTTTGGTTGGTTTTGAGACCGGGTCTGGCTCTGTAGCCCAAGCTGGAATGCGGTGGCGCGATCATGGCTCCCTGCAGCCTC
AAACTCCTGGGCTCAAGCAATCCTCCTGCCTCAGCCTCCCAAGCAGCTGGGAAGATAGGCACGTGCCACCACACCCGGCTAATTTTTTCT
TTATTTTTTTTGTAGAGATGGGGGTCTCACTATGTTGCCCAGGCTGGTCTCAAACTCCTGGGCTCAAGCGATCCTTTGGCCTCGGCCTCC
CAAAGTGCATGAGCCACCATGCCTGGCCTGTTTAGTTTTGTTTCAAGTTGAAATACCTTTCTTGTGTTTTCTAATTAGAAAAGTAATATC
TACTCATTGTAAAAACTCAAACAGTGCAGAAATGTAGAAAGTAGAAAGTGTAAGTCCCTGGTTGTCCCTTCTGCCTGAGACAACCACTGC
TCACAGTTTGATGTATATCCTTCCAGAGACTCTCAAATTTAAGCAAATAATTTTTATTACCATGTCTTTTTATTTGAAGACGTACATTTG
CCTCCAAAGTTCAACACAAGTTCAACTGACCATATCCTTCCATGACCTGAATAGATGCTATCCTTTATCACGATGTTCAATTGCCTTTGA
AAGAGAGTAGTCCAGGTATATTCCTGATCAAAATTTGGCATTTTTGATGATACTACTCTACACAGATCAGACTCATGTGCAGAATCGTGC
CTGGAGAGAGAGGTTTGGTTAAGACAGAGATTTCTGGAAACATTCAAATTGCAAATGGAAACTTGAAACCCACAATCTAATGAGGAATGT
ACTGGAAAAATAATCTGAAGAGTTGACAAATTGTGTACTAGATTGAACACATGGAATGCAATGCAATGAGACTTTCTGCACTAAAACTTA
TCCTCATATGTACAACAATGATGTGTGTATTATATAACAGTGATGTGTACATTTCTGACACCCCATACATAATATACACAGTTTGTATAA
ATGCATACATTTAAAAATATATATGTACAATACAGCTAACATAAAACTGTAGTACGCCTGAAGGATATTACTAGTGCCTAATATTGAGTA
TGAGTCACTGCGTGTTCGCATCAACTTGGAAGTGCAGTAATTGTTATAAAATTAATCAGTGCAGCCAACATTATTTATGAATCACATCTT
TGAAACTGTGCAGTAGCATATACATATATATTTTTAAATAACATTTTTCACAGTTTTCCAGAGTTACTGTTGAAATCTGCATCACCAAAA
AAAAAAAAAAGCAAGATTTTTTTAACAATGTAGACACTCTTCAGACCCAGTAATCTGCGTGTGATTTCCTATTTGTAGATTCCCAAGAGA
CTTTAGCAGTCACCAGCCTTAATGCATGTACAGGATATTATTGTGACTTAATTTATCTGCAGTTTTTAATCCATGTGAAATTGGAATTTA

>In-frame_REV1_ENST00000258428_chr2_100065798_-_AFF3_ENST00000409579_chr2_100185377_-_1695nt
CGGAGGGGGAGGGGCGGAGAGCCACCGCGGAGCGCGCGCGGGGTTGGTTGCCGCGAGCGTGGGGGAGCGTGGACCGCGGCGCTGCTCAGC
GGTGGGGCTGCCTTCCCCCGGCCCTCCTCCCTGGTCCCTGGCGAGGGCACTGGCGGCGGCGGGGCCGGGGTCCGCAAGGCCGGAGAAGGC
CGCCGGGCCCGGGCATGGTGGTCTGGGGCAACGCGGAAGAAGCTCCACCATGAGGCGAGGTGGATGGAGGAAGCGAGCTGAAAATGATGG
CTGGGAAACATGGGGTGGGTATATGGCTGCCAAGGTCCAGAAATTGGAGGAACAGTTTCGATCAGATGCTGCTATGCAGAAGGATGGGAC
TTCATCTACAATTTTTAGTGGAGTTGCCATCTATGTTAATGGATACACAGATCCTTCCGCTGAGGAATTGAGAAAACTAATGATGTTGCA
TGGAGGTCAATACCATGTATATTATTCCAGATCTAAAACAACACATATTATTGCCACAAATCTTCCCAATGCCAAAATTAAAGAATTAAA
GGGGGAAAAAGTAATTCGACCAGAATGGATTGTGGAAAGGCCTCGCAGTGCCGATTATTTTATGCAAGAAGCTAAACGAATGAAGCATAA
AGCAGATGCAATGGTGGAAAAGTTTGGAAAGGCTTTGAACTATGCTGAAGCAGCATTGTCGTTTATCGAGTGTGGAAATGCAATGGAACA
AGGCCCCATGGAATCCAAATCTCCTTATACGATGTATTCAGAAACAGTAGAGCTCATCAGGTATGCTATGAGACTAAAAACCCACTCAGG
CCCCAATGCCACACCAGAAGACAAACAACTGGCTGCATTATGTTACCGATGCCTGGCCCTCCTGTACTGGCGGATGTTTCGACTCAAAAG
GGACCACGCTGTAAAGTATTCAAAAGCACTAATCGACTATTTCAAGAACTCATCTAAAGCCGCCCAAGCCCCATCTCCGTGGGGGGCCAG
TGGAAAGAGCACTGGAACCCCATCCCCCATGTCTCCCAACCCCTCTCCCGCCAGCTCCGTGGGGTCTCAGGGCAGCCTCTCCAACGCCAG
CGCCCTGTCCCCGTCGACCATCGTCAGCATCCCACAGCGCATCCACCAGATGGCGGCCAACCACGTCAGCATCACCAACAGCATCCTGCA
CAGCTACGACTACTGGGAGATGGCCGACAACCTGGCCAAGGAAAACCGAGAATTCTTCAACGACCTGGATCTGCTCATGGGGCCGGTCAC
CCTGCACAGCAGCATGGAGCACCTGGTCCAGTACTCCCAACAGGGCCTGCACTGGCTGCGGAACAGCGCCCACCTGTCATAGGGACCTCA
CCCTGGGGCCAGAGTGGGCTCTGGTCTCCACAGATGGCTCAACGTTTTTGGACACTGTGCTACTGAAACTCCCAGCCACAGCATTTATCA
GACTGCGGTGAACATTTCCTCAGCATTGAACAATGATCTTTTGCAGGGCATGTGTGTTTGTATGTGTGGGTATATAAGAAGCCGCCTGTG
TATGTGTGTAAGATACACAGCTCTTCAGAACACACCTTCTTTGTCTAGTTTCCATAATCCCAGGCTAGACAAAGTGATCAGAGGTTTCTG


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FusionGenePPI for REV1_AFF3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
REV1MAD2L2, POLH, POLDIP2, HSP90AA1, HSP90AB1, PCNA, UBC, MYC, POLK, POLI, REV3L, C1orf86, REV1, CDC27, BRCA1, MSH2, POLD3, RELA, CLK1, PIAS4, TP53, FANCD2, FANCI, FHL2, TSC22D2AFF3MLLT3, CDK9, PIP4K2A


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneREV1chr2:100065798chr2:100185377ENST00000258428-423352_3621161252target DNA
HgeneREV1chr2:100065798chr2:100185377ENST00000258428-423653_6561161252target DNA
HgeneREV1chr2:100065798chr2:100185377ENST00000258428-423709_7171161252target DNA
HgeneREV1chr2:100065798chr2:100185377ENST00000393445-423352_3621161251target DNA
HgeneREV1chr2:100065798chr2:100185377ENST00000393445-423653_6561161251target DNA
HgeneREV1chr2:100065798chr2:100185377ENST00000393445-423709_7171161251target DNA


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for REV1_AFF3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for REV1_AFF3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneAFF3C0003873Rheumatoid Arthritis2CTD_human
TgeneAFF3C0236969Substance-Related Disorders1CTD_human