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Fusion gene ID: 30935 |
FusionGeneSummary for RELL1_SLC43A2 |
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Fusion gene information | Fusion gene name: RELL1_SLC43A2 | Fusion gene ID: 30935 | Hgene | Tgene | Gene symbol | RELL1 | SLC43A2 | Gene ID | 768211 | 124935 |
Gene name | RELT like 1 | solute carrier family 43 member 2 | |
Synonyms | - | LAT4 | |
Cytomap | 4p14 | 17p13.3 | |
Type of gene | protein-coding | protein-coding | |
Description | RELT-like protein 1receptor expressed in lymphoid tissues like 1tmp_locus_29 | large neutral amino acids transporter small subunit 4L-type amino acid transporter 4solute carrier family 43 (amino acid system L transporter), member 2 | |
Modification date | 20180519 | 20180523 | |
UniProtAcc | Q8IUW5 | Q8N370 | |
Ensembl transtripts involved in fusion gene | ENST00000314117, ENST00000454158, | ENST00000301335, ENST00000571650, ENST00000382147, ENST00000412517, ENST00000574274, | |
Fusion gene scores | * DoF score | 3 X 3 X 1=9 | 9 X 9 X 5=405 |
# samples | 3 | 9 | |
** MAII score | log2(3/9*10)=1.73696559416621 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(9/405*10)=-2.16992500144231 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
Context | PubMed: RELL1 [Title/Abstract] AND SLC43A2 [Title/Abstract] AND fusion [Title/Abstract] | ||
Functional or gene categories assigned by FusionGDB annotation |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
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Partner | Gene | GO ID | GO term | PubMed ID |
![]() (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChiTaRS3.1 | BG002707 | RELL1 | chr4 | 37640069 | - | SLC43A2 | chr17 | 1505674 | - |
* LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
5CDS-intron | ENST00000314117 | ENST00000301335 | RELL1 | chr4 | 37640069 | - | SLC43A2 | chr17 | 1505674 | - |
5CDS-intron | ENST00000314117 | ENST00000571650 | RELL1 | chr4 | 37640069 | - | SLC43A2 | chr17 | 1505674 | - |
5CDS-intron | ENST00000314117 | ENST00000382147 | RELL1 | chr4 | 37640069 | - | SLC43A2 | chr17 | 1505674 | - |
5CDS-intron | ENST00000314117 | ENST00000412517 | RELL1 | chr4 | 37640069 | - | SLC43A2 | chr17 | 1505674 | - |
5CDS-intron | ENST00000314117 | ENST00000574274 | RELL1 | chr4 | 37640069 | - | SLC43A2 | chr17 | 1505674 | - |
5CDS-intron | ENST00000454158 | ENST00000301335 | RELL1 | chr4 | 37640069 | - | SLC43A2 | chr17 | 1505674 | - |
5CDS-intron | ENST00000454158 | ENST00000571650 | RELL1 | chr4 | 37640069 | - | SLC43A2 | chr17 | 1505674 | - |
5CDS-intron | ENST00000454158 | ENST00000382147 | RELL1 | chr4 | 37640069 | - | SLC43A2 | chr17 | 1505674 | - |
5CDS-intron | ENST00000454158 | ENST00000412517 | RELL1 | chr4 | 37640069 | - | SLC43A2 | chr17 | 1505674 | - |
5CDS-intron | ENST00000454158 | ENST00000574274 | RELL1 | chr4 | 37640069 | - | SLC43A2 | chr17 | 1505674 | - |
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FusionProtFeatures for RELL1_SLC43A2 |
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Hgene | Tgene |
RELL1 | SLC43A2 |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for RELL1_SLC43A2 |
![]() (nt: nucleotides, aa: amino acids) |
* Fusion amino acid sequences. |
* Fusion transcript sequences (only coding sequence (CDS) region). |
* Fusion transcript sequences (Full-length transcript). |
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FusionGenePPI for RELL1_SLC43A2 |
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Hgene | Hgene's interactors | Tgene | Tgene's interactors |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for RELL1_SLC43A2 |
![]() (DrugBank Version 5.1.0 2018-04-02) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for RELL1_SLC43A2 |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Hgene | RELL1 | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |
Tgene | SLC43A2 | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |