FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact

Center for Computational Systems Medicine
leaf

FusionGeneSummary

leaf

FusionProtFeature

leaf

FusionGeneSequence

leaf

FusionGenePPI

leaf

RelatedDrugs

leaf

RelatedDiseases

Fusion gene ID: 30770

FusionGeneSummary for RBM47_RBM47

check button Fusion gene summary
Fusion gene informationFusion gene name: RBM47_RBM47
Fusion gene ID: 30770
HgeneTgene
Gene symbol

RBM47

RBM47

Gene ID

54502

54502

Gene nameRNA binding motif protein 47RNA binding motif protein 47
SynonymsNET18NET18
Cytomap

4p14

4p14

Type of geneprotein-codingprotein-coding
DescriptionRNA-binding protein 47RNA-binding protein 47
Modification date2018051920180519
UniProtAcc

A0AV96

A0AV96

Ensembl transtripts involved in fusion geneENST00000319592, ENST00000381793, 
ENST00000381795, ENST00000295971, 
ENST00000514014, ENST00000515809, 
ENST00000319592, ENST00000381793, 
ENST00000381795, ENST00000295971, 
ENST00000514014, ENST00000515809, 
Fusion gene scores* DoF score9 X 9 X 7=5676 X 7 X 3=126
# samples 137
** MAII scorelog2(13/567*10)=-2.12483711191377
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(7/126*10)=-0.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: RBM47 [Title/Abstract] AND RBM47 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS3.1BE833842RBM47chr4

40462058

-RBM47chr4

40462687

-
ChiTaRS3.1BF741816RBM47chr4

40543305

-RBM47chr4

40544649

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
intron-intronENST00000319592ENST00000319592RBM47chr4

40462058

-RBM47chr4

40462687

-
intron-intronENST00000319592ENST00000381793RBM47chr4

40462058

-RBM47chr4

40462687

-
intron-intronENST00000319592ENST00000381795RBM47chr4

40462058

-RBM47chr4

40462687

-
intron-intronENST00000319592ENST00000295971RBM47chr4

40462058

-RBM47chr4

40462687

-
intron-intronENST00000319592ENST00000514014RBM47chr4

40462058

-RBM47chr4

40462687

-
intron-intronENST00000319592ENST00000515809RBM47chr4

40462058

-RBM47chr4

40462687

-
intron-intronENST00000381793ENST00000319592RBM47chr4

40462058

-RBM47chr4

40462687

-
intron-intronENST00000381793ENST00000381793RBM47chr4

40462058

-RBM47chr4

40462687

-
intron-intronENST00000381793ENST00000381795RBM47chr4

40462058

-RBM47chr4

40462687

-
intron-intronENST00000381793ENST00000295971RBM47chr4

40462058

-RBM47chr4

40462687

-
intron-intronENST00000381793ENST00000514014RBM47chr4

40462058

-RBM47chr4

40462687

-
intron-intronENST00000381793ENST00000515809RBM47chr4

40462058

-RBM47chr4

40462687

-
intron-intronENST00000381795ENST00000319592RBM47chr4

40462058

-RBM47chr4

40462687

-
intron-intronENST00000381795ENST00000381793RBM47chr4

40462058

-RBM47chr4

40462687

-
intron-intronENST00000381795ENST00000381795RBM47chr4

40462058

-RBM47chr4

40462687

-
intron-intronENST00000381795ENST00000295971RBM47chr4

40462058

-RBM47chr4

40462687

-
intron-intronENST00000381795ENST00000514014RBM47chr4

40462058

-RBM47chr4

40462687

-
intron-intronENST00000381795ENST00000515809RBM47chr4

40462058

-RBM47chr4

40462687

-
intron-intronENST00000295971ENST00000319592RBM47chr4

40462058

-RBM47chr4

40462687

-
intron-intronENST00000295971ENST00000381793RBM47chr4

40462058

-RBM47chr4

40462687

-
intron-intronENST00000295971ENST00000381795RBM47chr4

40462058

-RBM47chr4

40462687

-
intron-intronENST00000295971ENST00000295971RBM47chr4

40462058

-RBM47chr4

40462687

-
intron-intronENST00000295971ENST00000514014RBM47chr4

40462058

-RBM47chr4

40462687

-
intron-intronENST00000295971ENST00000515809RBM47chr4

40462058

-RBM47chr4

40462687

-
intron-intronENST00000514014ENST00000319592RBM47chr4

40462058

-RBM47chr4

40462687

-
intron-intronENST00000514014ENST00000381793RBM47chr4

40462058

-RBM47chr4

40462687

-
intron-intronENST00000514014ENST00000381795RBM47chr4

40462058

-RBM47chr4

40462687

-
intron-intronENST00000514014ENST00000295971RBM47chr4

40462058

-RBM47chr4

40462687

-
intron-intronENST00000514014ENST00000514014RBM47chr4

40462058

-RBM47chr4

40462687

-
intron-intronENST00000514014ENST00000515809RBM47chr4

40462058

-RBM47chr4

40462687

-
intron-intronENST00000515809ENST00000319592RBM47chr4

40462058

-RBM47chr4

40462687

-
intron-intronENST00000515809ENST00000381793RBM47chr4

40462058

-RBM47chr4

40462687

-
intron-intronENST00000515809ENST00000381795RBM47chr4

40462058

-RBM47chr4

40462687

-
intron-intronENST00000515809ENST00000295971RBM47chr4

40462058

-RBM47chr4

40462687

-
intron-intronENST00000515809ENST00000514014RBM47chr4

40462058

-RBM47chr4

40462687

-
intron-intronENST00000515809ENST00000515809RBM47chr4

40462058

-RBM47chr4

40462687

-
intron-intronENST00000319592ENST00000319592RBM47chr4

40543305

-RBM47chr4

40544649

-
intron-intronENST00000319592ENST00000381793RBM47chr4

40543305

-RBM47chr4

40544649

-
intron-intronENST00000319592ENST00000381795RBM47chr4

40543305

-RBM47chr4

40544649

-
intron-intronENST00000319592ENST00000295971RBM47chr4

40543305

-RBM47chr4

40544649

-
intron-intronENST00000319592ENST00000514014RBM47chr4

40543305

-RBM47chr4

40544649

-
intron-intronENST00000319592ENST00000515809RBM47chr4

40543305

-RBM47chr4

40544649

-
intron-intronENST00000381793ENST00000319592RBM47chr4

40543305

-RBM47chr4

40544649

-
intron-intronENST00000381793ENST00000381793RBM47chr4

40543305

-RBM47chr4

40544649

-
intron-intronENST00000381793ENST00000381795RBM47chr4

40543305

-RBM47chr4

40544649

-
intron-intronENST00000381793ENST00000295971RBM47chr4

40543305

-RBM47chr4

40544649

-
intron-intronENST00000381793ENST00000514014RBM47chr4

40543305

-RBM47chr4

40544649

-
intron-intronENST00000381793ENST00000515809RBM47chr4

40543305

-RBM47chr4

40544649

-
intron-intronENST00000381795ENST00000319592RBM47chr4

40543305

-RBM47chr4

40544649

-
intron-intronENST00000381795ENST00000381793RBM47chr4

40543305

-RBM47chr4

40544649

-
intron-intronENST00000381795ENST00000381795RBM47chr4

40543305

-RBM47chr4

40544649

-
intron-intronENST00000381795ENST00000295971RBM47chr4

40543305

-RBM47chr4

40544649

-
intron-intronENST00000381795ENST00000514014RBM47chr4

40543305

-RBM47chr4

40544649

-
intron-intronENST00000381795ENST00000515809RBM47chr4

40543305

-RBM47chr4

40544649

-
intron-intronENST00000295971ENST00000319592RBM47chr4

40543305

-RBM47chr4

40544649

-
intron-intronENST00000295971ENST00000381793RBM47chr4

40543305

-RBM47chr4

40544649

-
intron-intronENST00000295971ENST00000381795RBM47chr4

40543305

-RBM47chr4

40544649

-
intron-intronENST00000295971ENST00000295971RBM47chr4

40543305

-RBM47chr4

40544649

-
intron-intronENST00000295971ENST00000514014RBM47chr4

40543305

-RBM47chr4

40544649

-
intron-intronENST00000295971ENST00000515809RBM47chr4

40543305

-RBM47chr4

40544649

-
intron-intronENST00000514014ENST00000319592RBM47chr4

40543305

-RBM47chr4

40544649

-
intron-intronENST00000514014ENST00000381793RBM47chr4

40543305

-RBM47chr4

40544649

-
intron-intronENST00000514014ENST00000381795RBM47chr4

40543305

-RBM47chr4

40544649

-
intron-intronENST00000514014ENST00000295971RBM47chr4

40543305

-RBM47chr4

40544649

-
intron-intronENST00000514014ENST00000514014RBM47chr4

40543305

-RBM47chr4

40544649

-
intron-intronENST00000514014ENST00000515809RBM47chr4

40543305

-RBM47chr4

40544649

-
intron-intronENST00000515809ENST00000319592RBM47chr4

40543305

-RBM47chr4

40544649

-
intron-intronENST00000515809ENST00000381793RBM47chr4

40543305

-RBM47chr4

40544649

-
intron-intronENST00000515809ENST00000381795RBM47chr4

40543305

-RBM47chr4

40544649

-
intron-intronENST00000515809ENST00000295971RBM47chr4

40543305

-RBM47chr4

40544649

-
intron-intronENST00000515809ENST00000514014RBM47chr4

40543305

-RBM47chr4

40544649

-
intron-intronENST00000515809ENST00000515809RBM47chr4

40543305

-RBM47chr4

40544649

-

Top

FusionProtFeatures for RBM47_RBM47


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
RBM47

A0AV96

RBM47

A0AV96


check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


Top

FusionGeneSequence for RBM47_RBM47


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.

* Fusion transcript sequences (only coding sequence (CDS) region).

* Fusion transcript sequences (Full-length transcript).

Top

FusionGenePPI for RBM47_RBM47


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

RelatedDrugs for RBM47_RBM47


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

RelatedDiseases for RBM47_RBM47


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneRBM47C3495559Juvenile arthritis1CTD_human
TgeneRBM47C3495559Juvenile arthritis1CTD_human