|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 30676 |
FusionGeneSummary for RBL1_NDRG3 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: RBL1_NDRG3 | Fusion gene ID: 30676 | Hgene | Tgene | Gene symbol | RBL1 | NDRG3 | Gene ID | 5933 | 57446 |
| Gene name | RB transcriptional corepressor like 1 | NDRG family member 3 | |
| Synonyms | CP107|PRB1|p107 | - | |
| Cytomap | 20q11.23 | 20q11.23 | |
| Type of gene | protein-coding | protein-coding | |
| Description | retinoblastoma-like protein 1107 kDa retinoblastoma-associated proteinretinoblastoma-like 1 | protein NDRG3N-myc downstream-regulated gene 3 protein | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | P28749 | Q9UGV2 | |
| Ensembl transtripts involved in fusion gene | ENST00000373664, ENST00000344359, ENST00000598590, | ENST00000373803, ENST00000359675, ENST00000349004, ENST00000373773, ENST00000540765, | |
| Fusion gene scores | * DoF score | 7 X 3 X 5=105 | 5 X 6 X 4=120 |
| # samples | 7 | 6 | |
| ** MAII score | log2(7/105*10)=-0.584962500721156 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(6/120*10)=-1 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: RBL1 [Title/Abstract] AND NDRG3 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | RBL1 | GO:0043550 | regulation of lipid kinase activity | 16286473 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-C8-A12T-01A | RBL1 | chr20 | 35651053 | - | NDRG3 | chr20 | 35335410 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000373664 | ENST00000373803 | RBL1 | chr20 | 35651053 | - | NDRG3 | chr20 | 35335410 | - |
| 5CDS-intron | ENST00000373664 | ENST00000359675 | RBL1 | chr20 | 35651053 | - | NDRG3 | chr20 | 35335410 | - |
| 5CDS-intron | ENST00000373664 | ENST00000349004 | RBL1 | chr20 | 35651053 | - | NDRG3 | chr20 | 35335410 | - |
| 5CDS-5UTR | ENST00000373664 | ENST00000373773 | RBL1 | chr20 | 35651053 | - | NDRG3 | chr20 | 35335410 | - |
| 5CDS-intron | ENST00000373664 | ENST00000540765 | RBL1 | chr20 | 35651053 | - | NDRG3 | chr20 | 35335410 | - |
| In-frame | ENST00000344359 | ENST00000373803 | RBL1 | chr20 | 35651053 | - | NDRG3 | chr20 | 35335410 | - |
| 5CDS-intron | ENST00000344359 | ENST00000359675 | RBL1 | chr20 | 35651053 | - | NDRG3 | chr20 | 35335410 | - |
| 5CDS-intron | ENST00000344359 | ENST00000349004 | RBL1 | chr20 | 35651053 | - | NDRG3 | chr20 | 35335410 | - |
| 5CDS-5UTR | ENST00000344359 | ENST00000373773 | RBL1 | chr20 | 35651053 | - | NDRG3 | chr20 | 35335410 | - |
| 5CDS-intron | ENST00000344359 | ENST00000540765 | RBL1 | chr20 | 35651053 | - | NDRG3 | chr20 | 35335410 | - |
| intron-3CDS | ENST00000598590 | ENST00000373803 | RBL1 | chr20 | 35651053 | - | NDRG3 | chr20 | 35335410 | - |
| intron-intron | ENST00000598590 | ENST00000359675 | RBL1 | chr20 | 35651053 | - | NDRG3 | chr20 | 35335410 | - |
| intron-intron | ENST00000598590 | ENST00000349004 | RBL1 | chr20 | 35651053 | - | NDRG3 | chr20 | 35335410 | - |
| intron-5UTR | ENST00000598590 | ENST00000373773 | RBL1 | chr20 | 35651053 | - | NDRG3 | chr20 | 35335410 | - |
| intron-intron | ENST00000598590 | ENST00000540765 | RBL1 | chr20 | 35651053 | - | NDRG3 | chr20 | 35335410 | - |
Top |
FusionProtFeatures for RBL1_NDRG3 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| RBL1 | NDRG3 |
| Key regulator of entry into cell division. Directlyinvolved in heterochromatin formation by maintaining overallchromatin structure and, in particular, that of constitutiveheterochromatin by stabilizing histone methylation. Recruits andtargets histone methyltransferases KMT5B and KMT5C, leading toepigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor byrecruiting chromatin-modifying enzymes to promoters. Potentinhibitor of E2F-mediated trans-activation. Forms a complex withadenovirus E1A and with SV40 large T antigen. May bind andmodulate functionally certain cellular proteins with which T andE1A compete for pocket binding. May act as a tumor suppressor. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | RBL1 | chr20:35651053 | chr20:35335410 | ENST00000344359 | - | 17 | 21 | 385_584 | 853 | 1015 | Region | Note=Domain A |
| Hgene | RBL1 | chr20:35651053 | chr20:35335410 | ENST00000344359 | - | 17 | 21 | 585_780 | 853 | 1015 | Region | Note=Spacer |
| Hgene | RBL1 | chr20:35651053 | chr20:35335410 | ENST00000373664 | - | 17 | 22 | 385_584 | 853 | 1069 | Region | Note=Domain A |
| Hgene | RBL1 | chr20:35651053 | chr20:35335410 | ENST00000373664 | - | 17 | 22 | 585_780 | 853 | 1069 | Region | Note=Spacer |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >RBL1 | chr20:35651053 | chr20:35335410 | ENST00000344359 | - | 17 | 21 | 385_949 | 853 | 1015 | Region | Note=Pocket%3B binds T and E1A |
| Hgene | >RBL1 | chr20:35651053 | chr20:35335410 | ENST00000344359 | - | 17 | 21 | 781_949 | 853 | 1015 | Region | Note=Domain B |
| Hgene | >RBL1 | chr20:35651053 | chr20:35335410 | ENST00000373664 | - | 17 | 22 | 385_949 | 853 | 1069 | Region | Note=Pocket%3B binds T and E1A |
| Hgene | >RBL1 | chr20:35651053 | chr20:35335410 | ENST00000373664 | - | 17 | 22 | 781_949 | 853 | 1069 | Region | Note=Domain B |
Top |
FusionGeneSequence for RBL1_NDRG3 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_RBL1_ENST00000373664_chr20_35651053_-_NDRG3_ENST00000373803_chr20_35335410_-_1223aa MFEDKPHAEGAAVVAAAGEALQALCQELNLDEGSAAEALDDFTAIRGNYSLEGEVTHWLACSLYVACRKSIIPTVGKGIMEGNCVSLTRI LRSAKLSLIQFFSKMKKWMDMSNLPQEFRERIERLERNFEVSTVIFKKYEPIFLDIFQNPYEEPPKLPRSRKQRRIPCSVKDLFNFCWTL FVYTKGNFRMIGDDLVNSYHLLLCCLDLIFANAIMCPNRQDLLNPSFKGLPSDFHTADFTASEEPPCIIAVLCELHDGLLVEAKGIKEHY FKPYISKLFDRKILKGECLLDLSSFTDNSKAVNKEYEEYVLTVGDFDERIFLGADAEEEIGTPRKFTRDTPLGKLTAQANVEYNLQQHFE KKRSFAPSTPLTGRRYLREKEAVITPVASATQSVSRLQSIVAGLKNAPSDQLINIFESCVRNPVENIMKILKGIGETFCQHYTQSTDEQP GSHIDFAVNRLKLAEILYYKILETVMVQETRRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYSSPRTFPWIIEVLNLQPFYFYKVIEVV IRSEEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQVSANKVPTCEEVIFPNNFETGNGGNVQGHLPLMPMSPLMHPRVKEVRTDSG SLRRDMQPLSPISVHERYSSPTAGSAKRRLFGEDPPKEMLMDKIITEGTKLKIAPSSSITAENVSILPGQTLLTMATAPVTGTTGHKVTI PLHGVANDAGEITLIPLSMNTNQESKVKSPVSLTAHSLIGASPKQTNLTKAQEVHSTGINRPKRTGSLALFYRKVYHLASVRLRDLCLKL DVSNELRRKIWTCFEFTLVHCPDLMKDRHLDQLLLCAFYIMAKNGTRNFQDFDCQEHDIETTHGVVHVTIRGLPKGNRPVILTYHDIGLN HKSCFNAFFNFEDMQEITQHFAVCHVDAPGQQEGAPSFPTGYQYPTMDELAEMLPPVLTHLSLKSIIGIGVGAGAYILSRFALNHPELVE GLVLINVDPCAKGWIDWAASKLSGLTTNVVDIILAHHFGQEELQANLDLIQTYRMHIAQDINQDNLQLFLNSYNGRRDLEIERPILGQND NKSKTLKCSTLLVVGDNSPAVEAVVECNSRLNPINTTLLKMADCGGLPQVVQPGKLTEAFKYFLQGMGYIPYVQLSHLSTESVPSASMTR >In-frame_RBL1_ENST00000344359_chr20_35651053_-_NDRG3_ENST00000373803_chr20_35335410_-_1223aa MFEDKPHAEGAAVVAAAGEALQALCQELNLDEGSAAEALDDFTAIRGNYSLEGEVTHWLACSLYVACRKSIIPTVGKGIMEGNCVSLTRI LRSAKLSLIQFFSKMKKWMDMSNLPQEFRERIERLERNFEVSTVIFKKYEPIFLDIFQNPYEEPPKLPRSRKQRRIPCSVKDLFNFCWTL FVYTKGNFRMIGDDLVNSYHLLLCCLDLIFANAIMCPNRQDLLNPSFKGLPSDFHTADFTASEEPPCIIAVLCELHDGLLVEAKGIKEHY FKPYISKLFDRKILKGECLLDLSSFTDNSKAVNKEYEEYVLTVGDFDERIFLGADAEEEIGTPRKFTRDTPLGKLTAQANVEYNLQQHFE KKRSFAPSTPLTGRRYLREKEAVITPVASATQSVSRLQSIVAGLKNAPSDQLINIFESCVRNPVENIMKILKGIGETFCQHYTQSTDEQP GSHIDFAVNRLKLAEILYYKILETVMVQETRRLHGMDMSVLLEQDIFHRSLMACCLEIVLFAYSSPRTFPWIIEVLNLQPFYFYKVIEVV IRSEEGLSRDMVKHLNSIEEQILESLAWSHDSALWEALQVSANKVPTCEEVIFPNNFETGNGGNVQGHLPLMPMSPLMHPRVKEVRTDSG SLRRDMQPLSPISVHERYSSPTAGSAKRRLFGEDPPKEMLMDKIITEGTKLKIAPSSSITAENVSILPGQTLLTMATAPVTGTTGHKVTI PLHGVANDAGEITLIPLSMNTNQESKVKSPVSLTAHSLIGASPKQTNLTKAQEVHSTGINRPKRTGSLALFYRKVYHLASVRLRDLCLKL DVSNELRRKIWTCFEFTLVHCPDLMKDRHLDQLLLCAFYIMAKNGTRNFQDFDCQEHDIETTHGVVHVTIRGLPKGNRPVILTYHDIGLN HKSCFNAFFNFEDMQEITQHFAVCHVDAPGQQEGAPSFPTGYQYPTMDELAEMLPPVLTHLSLKSIIGIGVGAGAYILSRFALNHPELVE GLVLINVDPCAKGWIDWAASKLSGLTTNVVDIILAHHFGQEELQANLDLIQTYRMHIAQDINQDNLQLFLNSYNGRRDLEIERPILGQND NKSKTLKCSTLLVVGDNSPAVEAVVECNSRLNPINTTLLKMADCGGLPQVVQPGKLTEAFKYFLQGMGYIPYVQLSHLSTESVPSASMTR |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_RBL1_ENST00000373664_chr20_35651053_-_NDRG3_ENST00000373803_chr20_35335410_-_3669nt ATGTTCGAGGACAAGCCCCACGCTGAGGGGGCGGCGGTGGTCGCCGCAGCCGGGGAGGCGCTACAGGCCCTGTGCCAGGAGCTGAACCTG GACGAGGGGAGCGCGGCCGAAGCCCTGGACGACTTTACTGCCATCCGAGGCAACTACAGCCTAGAGGGAGAAGTTACACACTGGTTGGCA TGTTCATTATATGTTGCATGCCGCAAAAGCATTATTCCCACGGTTGGAAAGGGTATCATGGAAGGCAACTGTGTTTCACTTACCAGAATA CTACGTTCAGCTAAATTAAGTTTAATACAATTTTTTAGTAAAATGAAGAAATGGATGGACATGTCAAATCTACCACAAGAATTTCGTGAA CGTATAGAAAGGCTAGAGAGAAATTTTGAGGTGTCTACTGTAATATTCAAAAAATATGAGCCAATTTTTTTAGATATATTTCAAAATCCA TATGAAGAACCACCAAAGTTACCACGAAGCCGGAAGCAGAGGAGGATTCCTTGCAGTGTTAAGGATCTGTTTAATTTCTGTTGGACACTT TTTGTTTATACTAAGGGTAATTTTCGGATGATTGGGGATGACTTAGTAAACTCTTATCATTTACTTCTATGCTGCTTGGATCTGATTTTT GCCAATGCGATTATGTGCCCAAATAGACAAGACTTGCTAAATCCATCATTTAAAGGTTTACCATCTGATTTTCATACTGCTGACTTTACG GCTTCTGAAGAGCCACCCTGCATCATTGCTGTACTGTGTGAACTGCATGATGGACTTCTCGTAGAAGCAAAAGGAATAAAGGAGCACTAC TTTAAGCCATATATTTCAAAACTCTTTGACAGGAAGATATTAAAAGGAGAATGCCTCCTGGACCTTTCAAGTTTTACTGATAATAGCAAA GCAGTGAATAAGGAGTATGAAGAGTATGTTCTAACTGTTGGTGATTTTGATGAGAGGATCTTTTTGGGAGCAGACGCAGAAGAGGAAATT GGAACACCTCGAAAGTTCACTCGTGACACCCCATTAGGGAAACTGACAGCACAGGCTAATGTGGAGTATAACCTTCAACAGCACTTTGAA AAAAAAAGGTCATTTGCACCTTCTACCCCACTGACCGGACGGAGATATTTACGAGAAAAAGAAGCAGTCATTACTCCTGTTGCATCAGCC ACCCAAAGTGTGAGCCGGTTACAGAGTATTGTGGCTGGTCTGAAAAATGCACCAAGTGACCAACTTATAAATATTTTTGAATCTTGTGTG CGTAATCCTGTGGAAAACATTATGAAAATACTAAAAGGAATAGGAGAGACTTTCTGTCAACACTATACTCAATCAACAGATGAACAGCCA GGATCTCACATAGACTTTGCTGTAAACAGACTAAAGCTGGCAGAAATTTTGTATTATAAAATACTAGAGACTGTAATGGTTCAGGAAACA CGAAGACTTCATGGAATGGACATGTCAGTTCTTTTAGAGCAAGATATATTTCATCGTTCCTTGATGGCTTGTTGTTTGGAAATTGTGCTC TTTGCCTATAGCTCACCTCGTACTTTTCCTTGGATTATTGAAGTTCTCAACTTGCAACCATTTTACTTTTATAAGGTTATTGAGGTGGTG ATCCGCTCAGAAGAGGGGCTCTCAAGGGACATGGTGAAACACCTAAACAGCATTGAAGAACAGATTTTGGAGAGTTTAGCATGGAGTCAC GATTCTGCACTGTGGGAGGCTCTCCAGGTTTCTGCAAACAAAGTTCCTACCTGTGAAGAAGTTATATTCCCAAATAACTTTGAAACAGGA AATGGAGGAAATGTGCAGGGACATCTTCCCCTGATGCCAATGTCTCCTCTAATGCACCCAAGAGTCAAGGAAGTTCGAACTGACAGTGGG AGTCTTCGAAGAGATATGCAACCATTGTCTCCAATTTCTGTCCATGAACGCTACAGTTCTCCTACCGCAGGGAGTGCTAAGAGAAGACTC TTTGGAGAGGACCCCCCAAAGGAAATGCTTATGGACAAGATCATAACAGAAGGAACAAAATTGAAAATCGCTCCTTCTTCAAGCATTACT GCTGAAAATGTATCAATTTTACCTGGTCAAACTCTTCTAACAATGGCCACAGCCCCAGTAACAGGAACAACAGGACATAAAGTTACAATT CCATTACATGGTGTCGCAAATGATGCTGGAGAGATCACACTGATACCTCTTTCCATGAATACAAATCAGGAGTCCAAAGTCAAGAGTCCT GTATCACTTACTGCTCATTCATTAATTGGTGCTTCTCCAAAACAGACCAATCTGACTAAAGCACAAGAGGTACATTCAACTGGAATAAAC AGGCCAAAGAGAACTGGGTCCTTAGCACTATTTTACAGAAAGGTCTATCATTTGGCAAGTGTACGCTTACGTGATCTATGTCTAAAACTG GATGTTTCAAATGAGTTACGAAGGAAGATATGGACGTGTTTTGAATTCACTTTAGTTCACTGTCCTGATCTAATGAAAGACAGGCATTTG GATCAGCTCCTCCTTTGTGCCTTTTATATCATGGCAAAGAATGGTACAAGAAACTTCCAGGACTTTGACTGTCAGGAACATGATATAGAA ACAACTCATGGTGTGGTCCACGTCACTATAAGAGGCTTACCCAAAGGAAACAGACCAGTTATACTAACATATCATGACATTGGCCTCAAC CATAAATCCTGTTTCAATGCATTCTTTAACTTTGAGGATATGCAAGAGATCACCCAGCACTTTGCTGTCTGTCATGTGGATGCCCCAGGC CAGCAGGAAGGTGCACCCTCTTTCCCAACAGGGTATCAGTACCCCACAATGGATGAGCTGGCTGAAATGCTGCCTCCTGTTCTTACCCAC CTAAGCCTGAAAAGCATCATTGGAATTGGAGTTGGAGCTGGAGCTTACATCCTCAGCAGATTTGCACTCAACCATCCAGAGCTTGTGGAA GGCCTTGTGCTCATTAATGTTGACCCTTGCGCTAAAGGCTGGATTGACTGGGCAGCTTCCAAACTCTCTGGCCTGACAACCAATGTTGTG GACATTATTTTGGCTCATCACTTTGGGCAGGAAGAGTTACAGGCCAACCTGGACCTGATCCAAACCTACAGAATGCATATTGCCCAAGAC ATCAACCAAGACAACCTGCAGCTCTTCTTGAATTCCTACAATGGACGCAGAGACCTGGAGATCGAAAGACCCATACTGGGCCAAAATGAT AACAAATCAAAAACATTAAAGTGTTCTACTTTACTGGTGGTAGGGGACAATTCGCCTGCAGTTGAGGCTGTGGTCGAATGCAATTCCCGC CTGAACCCTATAAATACAACTTTGCTAAAGATGGCGGACTGTGGGGGACTGCCCCAGGTAGTTCAGCCTGGGAAGCTCACCGAGGCCTTC AAGTACTTTTTGCAGGGAATGGGCTACATCCCGTATGTGCAGCTCAGTCACCTGAGCACCGAGTCAGTACCATCTGCCAGCATGACTCGG CTCGCCCGATCACGAACCCACTCAACCTCGAGTAGCCTCGGCTCTGGAGAAAGTCCCTTCAGCCGGTCTGTCACCAGCAATCAGTCAGAT >In-frame_RBL1_ENST00000344359_chr20_35651053_-_NDRG3_ENST00000373803_chr20_35335410_-_3669nt ATGTTCGAGGACAAGCCCCACGCTGAGGGGGCGGCGGTGGTCGCCGCAGCCGGGGAGGCGCTACAGGCCCTGTGCCAGGAGCTGAACCTG GACGAGGGGAGCGCGGCCGAAGCCCTGGACGACTTTACTGCCATCCGAGGCAACTACAGCCTAGAGGGAGAAGTTACACACTGGTTGGCA TGTTCATTATATGTTGCATGCCGCAAAAGCATTATTCCCACGGTTGGAAAGGGTATCATGGAAGGCAACTGTGTTTCACTTACCAGAATA CTACGTTCAGCTAAATTAAGTTTAATACAATTTTTTAGTAAAATGAAGAAATGGATGGACATGTCAAATCTACCACAAGAATTTCGTGAA CGTATAGAAAGGCTAGAGAGAAATTTTGAGGTGTCTACTGTAATATTCAAAAAATATGAGCCAATTTTTTTAGATATATTTCAAAATCCA TATGAAGAACCACCAAAGTTACCACGAAGCCGGAAGCAGAGGAGGATTCCTTGCAGTGTTAAGGATCTGTTTAATTTCTGTTGGACACTT TTTGTTTATACTAAGGGTAATTTTCGGATGATTGGGGATGACTTAGTAAACTCTTATCATTTACTTCTATGCTGCTTGGATCTGATTTTT GCCAATGCGATTATGTGCCCAAATAGACAAGACTTGCTAAATCCATCATTTAAAGGTTTACCATCTGATTTTCATACTGCTGACTTTACG GCTTCTGAAGAGCCACCCTGCATCATTGCTGTACTGTGTGAACTGCATGATGGACTTCTCGTAGAAGCAAAAGGAATAAAGGAGCACTAC TTTAAGCCATATATTTCAAAACTCTTTGACAGGAAGATATTAAAAGGAGAATGCCTCCTGGACCTTTCAAGTTTTACTGATAATAGCAAA GCAGTGAATAAGGAGTATGAAGAGTATGTTCTAACTGTTGGTGATTTTGATGAGAGGATCTTTTTGGGAGCAGACGCAGAAGAGGAAATT GGAACACCTCGAAAGTTCACTCGTGACACCCCATTAGGGAAACTGACAGCACAGGCTAATGTGGAGTATAACCTTCAACAGCACTTTGAA AAAAAAAGGTCATTTGCACCTTCTACCCCACTGACCGGACGGAGATATTTACGAGAAAAAGAAGCAGTCATTACTCCTGTTGCATCAGCC ACCCAAAGTGTGAGCCGGTTACAGAGTATTGTGGCTGGTCTGAAAAATGCACCAAGTGACCAACTTATAAATATTTTTGAATCTTGTGTG CGTAATCCTGTGGAAAACATTATGAAAATACTAAAAGGAATAGGAGAGACTTTCTGTCAACACTATACTCAATCAACAGATGAACAGCCA GGATCTCACATAGACTTTGCTGTAAACAGACTAAAGCTGGCAGAAATTTTGTATTATAAAATACTAGAGACTGTAATGGTTCAGGAAACA CGAAGACTTCATGGAATGGACATGTCAGTTCTTTTAGAGCAAGATATATTTCATCGTTCCTTGATGGCTTGTTGTTTGGAAATTGTGCTC TTTGCCTATAGCTCACCTCGTACTTTTCCTTGGATTATTGAAGTTCTCAACTTGCAACCATTTTACTTTTATAAGGTTATTGAGGTGGTG ATCCGCTCAGAAGAGGGGCTCTCAAGGGACATGGTGAAACACCTAAACAGCATTGAAGAACAGATTTTGGAGAGTTTAGCATGGAGTCAC GATTCTGCACTGTGGGAGGCTCTCCAGGTTTCTGCAAACAAAGTTCCTACCTGTGAAGAAGTTATATTCCCAAATAACTTTGAAACAGGA AATGGAGGAAATGTGCAGGGACATCTTCCCCTGATGCCAATGTCTCCTCTAATGCACCCAAGAGTCAAGGAAGTTCGAACTGACAGTGGG AGTCTTCGAAGAGATATGCAACCATTGTCTCCAATTTCTGTCCATGAACGCTACAGTTCTCCTACCGCAGGGAGTGCTAAGAGAAGACTC TTTGGAGAGGACCCCCCAAAGGAAATGCTTATGGACAAGATCATAACAGAAGGAACAAAATTGAAAATCGCTCCTTCTTCAAGCATTACT GCTGAAAATGTATCAATTTTACCTGGTCAAACTCTTCTAACAATGGCCACAGCCCCAGTAACAGGAACAACAGGACATAAAGTTACAATT CCATTACATGGTGTCGCAAATGATGCTGGAGAGATCACACTGATACCTCTTTCCATGAATACAAATCAGGAGTCCAAAGTCAAGAGTCCT GTATCACTTACTGCTCATTCATTAATTGGTGCTTCTCCAAAACAGACCAATCTGACTAAAGCACAAGAGGTACATTCAACTGGAATAAAC AGGCCAAAGAGAACTGGGTCCTTAGCACTATTTTACAGAAAGGTCTATCATTTGGCAAGTGTACGCTTACGTGATCTATGTCTAAAACTG GATGTTTCAAATGAGTTACGAAGGAAGATATGGACGTGTTTTGAATTCACTTTAGTTCACTGTCCTGATCTAATGAAAGACAGGCATTTG GATCAGCTCCTCCTTTGTGCCTTTTATATCATGGCAAAGAATGGTACAAGAAACTTCCAGGACTTTGACTGTCAGGAACATGATATAGAA ACAACTCATGGTGTGGTCCACGTCACTATAAGAGGCTTACCCAAAGGAAACAGACCAGTTATACTAACATATCATGACATTGGCCTCAAC CATAAATCCTGTTTCAATGCATTCTTTAACTTTGAGGATATGCAAGAGATCACCCAGCACTTTGCTGTCTGTCATGTGGATGCCCCAGGC CAGCAGGAAGGTGCACCCTCTTTCCCAACAGGGTATCAGTACCCCACAATGGATGAGCTGGCTGAAATGCTGCCTCCTGTTCTTACCCAC CTAAGCCTGAAAAGCATCATTGGAATTGGAGTTGGAGCTGGAGCTTACATCCTCAGCAGATTTGCACTCAACCATCCAGAGCTTGTGGAA GGCCTTGTGCTCATTAATGTTGACCCTTGCGCTAAAGGCTGGATTGACTGGGCAGCTTCCAAACTCTCTGGCCTGACAACCAATGTTGTG GACATTATTTTGGCTCATCACTTTGGGCAGGAAGAGTTACAGGCCAACCTGGACCTGATCCAAACCTACAGAATGCATATTGCCCAAGAC ATCAACCAAGACAACCTGCAGCTCTTCTTGAATTCCTACAATGGACGCAGAGACCTGGAGATCGAAAGACCCATACTGGGCCAAAATGAT AACAAATCAAAAACATTAAAGTGTTCTACTTTACTGGTGGTAGGGGACAATTCGCCTGCAGTTGAGGCTGTGGTCGAATGCAATTCCCGC CTGAACCCTATAAATACAACTTTGCTAAAGATGGCGGACTGTGGGGGACTGCCCCAGGTAGTTCAGCCTGGGAAGCTCACCGAGGCCTTC AAGTACTTTTTGCAGGGAATGGGCTACATCCCGTATGTGCAGCTCAGTCACCTGAGCACCGAGTCAGTACCATCTGCCAGCATGACTCGG CTCGCCCGATCACGAACCCACTCAACCTCGAGTAGCCTCGGCTCTGGAGAAAGTCCCTTCAGCCGGTCTGTCACCAGCAATCAGTCAGAT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_RBL1_ENST00000373664_chr20_35651053_-_NDRG3_ENST00000373803_chr20_35335410_-_5490nt GGGTAGCGCGCCTGGGAGGGAGAAAGAAGTCGGGGGCCGTGGCGCGCAGCCCGCGGGGCCTGAAGGGATGTTCGAGGACAAGCCCCACGC TGAGGGGGCGGCGGTGGTCGCCGCAGCCGGGGAGGCGCTACAGGCCCTGTGCCAGGAGCTGAACCTGGACGAGGGGAGCGCGGCCGAAGC CCTGGACGACTTTACTGCCATCCGAGGCAACTACAGCCTAGAGGGAGAAGTTACACACTGGTTGGCATGTTCATTATATGTTGCATGCCG CAAAAGCATTATTCCCACGGTTGGAAAGGGTATCATGGAAGGCAACTGTGTTTCACTTACCAGAATACTACGTTCAGCTAAATTAAGTTT AATACAATTTTTTAGTAAAATGAAGAAATGGATGGACATGTCAAATCTACCACAAGAATTTCGTGAACGTATAGAAAGGCTAGAGAGAAA TTTTGAGGTGTCTACTGTAATATTCAAAAAATATGAGCCAATTTTTTTAGATATATTTCAAAATCCATATGAAGAACCACCAAAGTTACC ACGAAGCCGGAAGCAGAGGAGGATTCCTTGCAGTGTTAAGGATCTGTTTAATTTCTGTTGGACACTTTTTGTTTATACTAAGGGTAATTT TCGGATGATTGGGGATGACTTAGTAAACTCTTATCATTTACTTCTATGCTGCTTGGATCTGATTTTTGCCAATGCGATTATGTGCCCAAA TAGACAAGACTTGCTAAATCCATCATTTAAAGGTTTACCATCTGATTTTCATACTGCTGACTTTACGGCTTCTGAAGAGCCACCCTGCAT CATTGCTGTACTGTGTGAACTGCATGATGGACTTCTCGTAGAAGCAAAAGGAATAAAGGAGCACTACTTTAAGCCATATATTTCAAAACT CTTTGACAGGAAGATATTAAAAGGAGAATGCCTCCTGGACCTTTCAAGTTTTACTGATAATAGCAAAGCAGTGAATAAGGAGTATGAAGA GTATGTTCTAACTGTTGGTGATTTTGATGAGAGGATCTTTTTGGGAGCAGACGCAGAAGAGGAAATTGGAACACCTCGAAAGTTCACTCG TGACACCCCATTAGGGAAACTGACAGCACAGGCTAATGTGGAGTATAACCTTCAACAGCACTTTGAAAAAAAAAGGTCATTTGCACCTTC TACCCCACTGACCGGACGGAGATATTTACGAGAAAAAGAAGCAGTCATTACTCCTGTTGCATCAGCCACCCAAAGTGTGAGCCGGTTACA GAGTATTGTGGCTGGTCTGAAAAATGCACCAAGTGACCAACTTATAAATATTTTTGAATCTTGTGTGCGTAATCCTGTGGAAAACATTAT GAAAATACTAAAAGGAATAGGAGAGACTTTCTGTCAACACTATACTCAATCAACAGATGAACAGCCAGGATCTCACATAGACTTTGCTGT AAACAGACTAAAGCTGGCAGAAATTTTGTATTATAAAATACTAGAGACTGTAATGGTTCAGGAAACACGAAGACTTCATGGAATGGACAT GTCAGTTCTTTTAGAGCAAGATATATTTCATCGTTCCTTGATGGCTTGTTGTTTGGAAATTGTGCTCTTTGCCTATAGCTCACCTCGTAC TTTTCCTTGGATTATTGAAGTTCTCAACTTGCAACCATTTTACTTTTATAAGGTTATTGAGGTGGTGATCCGCTCAGAAGAGGGGCTCTC AAGGGACATGGTGAAACACCTAAACAGCATTGAAGAACAGATTTTGGAGAGTTTAGCATGGAGTCACGATTCTGCACTGTGGGAGGCTCT CCAGGTTTCTGCAAACAAAGTTCCTACCTGTGAAGAAGTTATATTCCCAAATAACTTTGAAACAGGAAATGGAGGAAATGTGCAGGGACA TCTTCCCCTGATGCCAATGTCTCCTCTAATGCACCCAAGAGTCAAGGAAGTTCGAACTGACAGTGGGAGTCTTCGAAGAGATATGCAACC ATTGTCTCCAATTTCTGTCCATGAACGCTACAGTTCTCCTACCGCAGGGAGTGCTAAGAGAAGACTCTTTGGAGAGGACCCCCCAAAGGA AATGCTTATGGACAAGATCATAACAGAAGGAACAAAATTGAAAATCGCTCCTTCTTCAAGCATTACTGCTGAAAATGTATCAATTTTACC TGGTCAAACTCTTCTAACAATGGCCACAGCCCCAGTAACAGGAACAACAGGACATAAAGTTACAATTCCATTACATGGTGTCGCAAATGA TGCTGGAGAGATCACACTGATACCTCTTTCCATGAATACAAATCAGGAGTCCAAAGTCAAGAGTCCTGTATCACTTACTGCTCATTCATT AATTGGTGCTTCTCCAAAACAGACCAATCTGACTAAAGCACAAGAGGTACATTCAACTGGAATAAACAGGCCAAAGAGAACTGGGTCCTT AGCACTATTTTACAGAAAGGTCTATCATTTGGCAAGTGTACGCTTACGTGATCTATGTCTAAAACTGGATGTTTCAAATGAGTTACGAAG GAAGATATGGACGTGTTTTGAATTCACTTTAGTTCACTGTCCTGATCTAATGAAAGACAGGCATTTGGATCAGCTCCTCCTTTGTGCCTT TTATATCATGGCAAAGAATGGTACAAGAAACTTCCAGGACTTTGACTGTCAGGAACATGATATAGAAACAACTCATGGTGTGGTCCACGT CACTATAAGAGGCTTACCCAAAGGAAACAGACCAGTTATACTAACATATCATGACATTGGCCTCAACCATAAATCCTGTTTCAATGCATT CTTTAACTTTGAGGATATGCAAGAGATCACCCAGCACTTTGCTGTCTGTCATGTGGATGCCCCAGGCCAGCAGGAAGGTGCACCCTCTTT CCCAACAGGGTATCAGTACCCCACAATGGATGAGCTGGCTGAAATGCTGCCTCCTGTTCTTACCCACCTAAGCCTGAAAAGCATCATTGG AATTGGAGTTGGAGCTGGAGCTTACATCCTCAGCAGATTTGCACTCAACCATCCAGAGCTTGTGGAAGGCCTTGTGCTCATTAATGTTGA CCCTTGCGCTAAAGGCTGGATTGACTGGGCAGCTTCCAAACTCTCTGGCCTGACAACCAATGTTGTGGACATTATTTTGGCTCATCACTT TGGGCAGGAAGAGTTACAGGCCAACCTGGACCTGATCCAAACCTACAGAATGCATATTGCCCAAGACATCAACCAAGACAACCTGCAGCT CTTCTTGAATTCCTACAATGGACGCAGAGACCTGGAGATCGAAAGACCCATACTGGGCCAAAATGATAACAAATCAAAAACATTAAAGTG TTCTACTTTACTGGTGGTAGGGGACAATTCGCCTGCAGTTGAGGCTGTGGTCGAATGCAATTCCCGCCTGAACCCTATAAATACAACTTT GCTAAAGATGGCGGACTGTGGGGGACTGCCCCAGGTAGTTCAGCCTGGGAAGCTCACCGAGGCCTTCAAGTACTTTTTGCAGGGAATGGG CTACATCCCGTATGTGCAGCTCAGTCACCTGAGCACCGAGTCAGTACCATCTGCCAGCATGACTCGGCTCGCCCGATCACGAACCCACTC AACCTCGAGTAGCCTCGGCTCTGGAGAAAGTCCCTTCAGCCGGTCTGTCACCAGCAATCAGTCAGATGGAACTCAAGAATCCTGTGAGTC CCCTGATGTCCTGGACAGACACCAGACCATGGAGGTGTCCTGCTAAGCAGATGCTCCTCCCCTGGACCATTGCAAGTCCATCCTTCAAAT GACCACTCCATAATATAACATTTCATCCAGTAAACTGGCCTCTACTATCTTTAACTCATGCATGGCCACTGAACCTCTCTCTAGTAGCCT GGATTTATCATTCTCTCTGCCTGCCCACCCCCTTTTTTGTATAGCCCAAGAACCACTTCCATGCCATACTGTAACATTCCAACATCTTTA GCTGATCAGATCTCTCCATATCCTCTCTTGCCAGCTTTTTCCCGTGCTCCCCCAACTATGTATCAGATAAGATTCTTTGATCCCGACTCT GTGTGTGCGAGCACGCGTGTCTGTGTTTGTGTGTGCATAGTTCTGTGGTTTTAGACACGCTTTCTTGTAGTGCTTCTGCAAAAAACAAAA AAGGGACTTATTTTGCATTCTCAATGGTGTTTTTAAGGGAATTAGGCAGAACAGATTTCTAGGTTGGGTAGGCCACTGCATTCTCTTTTG TTTGCAAATTGGTCAACAAAATTTGCAAAGTGATTTCAGGAGAGAGCAGCTTTGAGGAATGTGGAAAATCATAATTGCCGTCTGGACCAT TGATTGATTGTGACCAGTAGCAGAAGGGTGCCTGTTACATAGAGAGGCTCCTTCTGTCCAAATGAATTTCTGTATACTCTTCTATAAATA AAAGGGAGGAATATATTCTGCTGGAAGCCCATGAACCATCGCTGAGGTTCTGATACAACATAGAGTTTTTTCCAAGGAGTGAATGTGGTT TAATTACTGGACTCTCTTAGCACAGGAAGGTGGAAACAAAATGCCAGGCCTCTGCTCTGAAGAGCAAAACTGCTGTCGCTGCAGTATCTG ATACCAGACATCCACATATCCACAAGAAGTGCCTCTTAGGTCTGTGACAGAGAGTGTGTCTCCATTCCTCAGTTCCCAGAAAGGGGAGAG GTTTGGCCTAAAAAGCATGTAGATGGGGGAGAAATGGGTGGGGGGAGAGGAACAGCCATTAACACAGTATCATGTTTAACAAGTATAGCC TTGATTTCAGTAGATGTAATGGAAGCCAAATTAAATTGATACAGAACCCATTTCTCAGAGTCTTTTTTTTTTTTTGAGACAGAGTCTCGC TGTTACCCAGGCTGGAGTGCAATGGCGCAAACTTGGCTCACTGCAACCTCTGCCCCCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCC GAGTAGCTGAGACTACAGGCACCTGCCACCATACCCAGCTAAGTTATGTATTTTTAGTAGAGATGGAGTTTCACCATGTTGGCCAGGCTG GTCTCAAACTCCTGACCTCAGGTGATCCACCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGTCATTGCTCCCAGCCATTAG AAAGATTGTTAATCCTATGAACTCCCTTTTGTAGGAGAGAAAGGGCCAATCTGTAGGGGTAGCCCTGTCCAGGTAAAGTTGTTTTCAGCC TCATGTCTACTGTTAGGTGAGGGAGTCACAGCCAGACAGAGAGTATTGCTGGAGGGTGAGAGAATTGTGGAGACCAACTACCACATAGCA AGAGCCCAGCTCTTGGGAGCATTGAGATGTAAGCTCAGGGTTACACAGTTCCAAATCTTGGGAAGGGGCTTTTCAGACAGACTGTTTGCT TTCTGCTGAGATAAGGAATGCATCACTCTGCCAGAGTATGACTTTTTACAGATTATTAAATAAAGCTGCATATGTCTCATTGTTACCTGA >In-frame_RBL1_ENST00000344359_chr20_35651053_-_NDRG3_ENST00000373803_chr20_35335410_-_5484nt CGCGCCTGGGAGGGAGAAAGAAGTCGGGGGCCGTGGCGCGCAGCCCGCGGGGCCTGAAGGGATGTTCGAGGACAAGCCCCACGCTGAGGG GGCGGCGGTGGTCGCCGCAGCCGGGGAGGCGCTACAGGCCCTGTGCCAGGAGCTGAACCTGGACGAGGGGAGCGCGGCCGAAGCCCTGGA CGACTTTACTGCCATCCGAGGCAACTACAGCCTAGAGGGAGAAGTTACACACTGGTTGGCATGTTCATTATATGTTGCATGCCGCAAAAG CATTATTCCCACGGTTGGAAAGGGTATCATGGAAGGCAACTGTGTTTCACTTACCAGAATACTACGTTCAGCTAAATTAAGTTTAATACA ATTTTTTAGTAAAATGAAGAAATGGATGGACATGTCAAATCTACCACAAGAATTTCGTGAACGTATAGAAAGGCTAGAGAGAAATTTTGA GGTGTCTACTGTAATATTCAAAAAATATGAGCCAATTTTTTTAGATATATTTCAAAATCCATATGAAGAACCACCAAAGTTACCACGAAG CCGGAAGCAGAGGAGGATTCCTTGCAGTGTTAAGGATCTGTTTAATTTCTGTTGGACACTTTTTGTTTATACTAAGGGTAATTTTCGGAT GATTGGGGATGACTTAGTAAACTCTTATCATTTACTTCTATGCTGCTTGGATCTGATTTTTGCCAATGCGATTATGTGCCCAAATAGACA AGACTTGCTAAATCCATCATTTAAAGGTTTACCATCTGATTTTCATACTGCTGACTTTACGGCTTCTGAAGAGCCACCCTGCATCATTGC TGTACTGTGTGAACTGCATGATGGACTTCTCGTAGAAGCAAAAGGAATAAAGGAGCACTACTTTAAGCCATATATTTCAAAACTCTTTGA CAGGAAGATATTAAAAGGAGAATGCCTCCTGGACCTTTCAAGTTTTACTGATAATAGCAAAGCAGTGAATAAGGAGTATGAAGAGTATGT TCTAACTGTTGGTGATTTTGATGAGAGGATCTTTTTGGGAGCAGACGCAGAAGAGGAAATTGGAACACCTCGAAAGTTCACTCGTGACAC CCCATTAGGGAAACTGACAGCACAGGCTAATGTGGAGTATAACCTTCAACAGCACTTTGAAAAAAAAAGGTCATTTGCACCTTCTACCCC ACTGACCGGACGGAGATATTTACGAGAAAAAGAAGCAGTCATTACTCCTGTTGCATCAGCCACCCAAAGTGTGAGCCGGTTACAGAGTAT TGTGGCTGGTCTGAAAAATGCACCAAGTGACCAACTTATAAATATTTTTGAATCTTGTGTGCGTAATCCTGTGGAAAACATTATGAAAAT ACTAAAAGGAATAGGAGAGACTTTCTGTCAACACTATACTCAATCAACAGATGAACAGCCAGGATCTCACATAGACTTTGCTGTAAACAG ACTAAAGCTGGCAGAAATTTTGTATTATAAAATACTAGAGACTGTAATGGTTCAGGAAACACGAAGACTTCATGGAATGGACATGTCAGT TCTTTTAGAGCAAGATATATTTCATCGTTCCTTGATGGCTTGTTGTTTGGAAATTGTGCTCTTTGCCTATAGCTCACCTCGTACTTTTCC TTGGATTATTGAAGTTCTCAACTTGCAACCATTTTACTTTTATAAGGTTATTGAGGTGGTGATCCGCTCAGAAGAGGGGCTCTCAAGGGA CATGGTGAAACACCTAAACAGCATTGAAGAACAGATTTTGGAGAGTTTAGCATGGAGTCACGATTCTGCACTGTGGGAGGCTCTCCAGGT TTCTGCAAACAAAGTTCCTACCTGTGAAGAAGTTATATTCCCAAATAACTTTGAAACAGGAAATGGAGGAAATGTGCAGGGACATCTTCC CCTGATGCCAATGTCTCCTCTAATGCACCCAAGAGTCAAGGAAGTTCGAACTGACAGTGGGAGTCTTCGAAGAGATATGCAACCATTGTC TCCAATTTCTGTCCATGAACGCTACAGTTCTCCTACCGCAGGGAGTGCTAAGAGAAGACTCTTTGGAGAGGACCCCCCAAAGGAAATGCT TATGGACAAGATCATAACAGAAGGAACAAAATTGAAAATCGCTCCTTCTTCAAGCATTACTGCTGAAAATGTATCAATTTTACCTGGTCA AACTCTTCTAACAATGGCCACAGCCCCAGTAACAGGAACAACAGGACATAAAGTTACAATTCCATTACATGGTGTCGCAAATGATGCTGG AGAGATCACACTGATACCTCTTTCCATGAATACAAATCAGGAGTCCAAAGTCAAGAGTCCTGTATCACTTACTGCTCATTCATTAATTGG TGCTTCTCCAAAACAGACCAATCTGACTAAAGCACAAGAGGTACATTCAACTGGAATAAACAGGCCAAAGAGAACTGGGTCCTTAGCACT ATTTTACAGAAAGGTCTATCATTTGGCAAGTGTACGCTTACGTGATCTATGTCTAAAACTGGATGTTTCAAATGAGTTACGAAGGAAGAT ATGGACGTGTTTTGAATTCACTTTAGTTCACTGTCCTGATCTAATGAAAGACAGGCATTTGGATCAGCTCCTCCTTTGTGCCTTTTATAT CATGGCAAAGAATGGTACAAGAAACTTCCAGGACTTTGACTGTCAGGAACATGATATAGAAACAACTCATGGTGTGGTCCACGTCACTAT AAGAGGCTTACCCAAAGGAAACAGACCAGTTATACTAACATATCATGACATTGGCCTCAACCATAAATCCTGTTTCAATGCATTCTTTAA CTTTGAGGATATGCAAGAGATCACCCAGCACTTTGCTGTCTGTCATGTGGATGCCCCAGGCCAGCAGGAAGGTGCACCCTCTTTCCCAAC AGGGTATCAGTACCCCACAATGGATGAGCTGGCTGAAATGCTGCCTCCTGTTCTTACCCACCTAAGCCTGAAAAGCATCATTGGAATTGG AGTTGGAGCTGGAGCTTACATCCTCAGCAGATTTGCACTCAACCATCCAGAGCTTGTGGAAGGCCTTGTGCTCATTAATGTTGACCCTTG CGCTAAAGGCTGGATTGACTGGGCAGCTTCCAAACTCTCTGGCCTGACAACCAATGTTGTGGACATTATTTTGGCTCATCACTTTGGGCA GGAAGAGTTACAGGCCAACCTGGACCTGATCCAAACCTACAGAATGCATATTGCCCAAGACATCAACCAAGACAACCTGCAGCTCTTCTT GAATTCCTACAATGGACGCAGAGACCTGGAGATCGAAAGACCCATACTGGGCCAAAATGATAACAAATCAAAAACATTAAAGTGTTCTAC TTTACTGGTGGTAGGGGACAATTCGCCTGCAGTTGAGGCTGTGGTCGAATGCAATTCCCGCCTGAACCCTATAAATACAACTTTGCTAAA GATGGCGGACTGTGGGGGACTGCCCCAGGTAGTTCAGCCTGGGAAGCTCACCGAGGCCTTCAAGTACTTTTTGCAGGGAATGGGCTACAT CCCGTATGTGCAGCTCAGTCACCTGAGCACCGAGTCAGTACCATCTGCCAGCATGACTCGGCTCGCCCGATCACGAACCCACTCAACCTC GAGTAGCCTCGGCTCTGGAGAAAGTCCCTTCAGCCGGTCTGTCACCAGCAATCAGTCAGATGGAACTCAAGAATCCTGTGAGTCCCCTGA TGTCCTGGACAGACACCAGACCATGGAGGTGTCCTGCTAAGCAGATGCTCCTCCCCTGGACCATTGCAAGTCCATCCTTCAAATGACCAC TCCATAATATAACATTTCATCCAGTAAACTGGCCTCTACTATCTTTAACTCATGCATGGCCACTGAACCTCTCTCTAGTAGCCTGGATTT ATCATTCTCTCTGCCTGCCCACCCCCTTTTTTGTATAGCCCAAGAACCACTTCCATGCCATACTGTAACATTCCAACATCTTTAGCTGAT CAGATCTCTCCATATCCTCTCTTGCCAGCTTTTTCCCGTGCTCCCCCAACTATGTATCAGATAAGATTCTTTGATCCCGACTCTGTGTGT GCGAGCACGCGTGTCTGTGTTTGTGTGTGCATAGTTCTGTGGTTTTAGACACGCTTTCTTGTAGTGCTTCTGCAAAAAACAAAAAAGGGA CTTATTTTGCATTCTCAATGGTGTTTTTAAGGGAATTAGGCAGAACAGATTTCTAGGTTGGGTAGGCCACTGCATTCTCTTTTGTTTGCA AATTGGTCAACAAAATTTGCAAAGTGATTTCAGGAGAGAGCAGCTTTGAGGAATGTGGAAAATCATAATTGCCGTCTGGACCATTGATTG ATTGTGACCAGTAGCAGAAGGGTGCCTGTTACATAGAGAGGCTCCTTCTGTCCAAATGAATTTCTGTATACTCTTCTATAAATAAAAGGG AGGAATATATTCTGCTGGAAGCCCATGAACCATCGCTGAGGTTCTGATACAACATAGAGTTTTTTCCAAGGAGTGAATGTGGTTTAATTA CTGGACTCTCTTAGCACAGGAAGGTGGAAACAAAATGCCAGGCCTCTGCTCTGAAGAGCAAAACTGCTGTCGCTGCAGTATCTGATACCA GACATCCACATATCCACAAGAAGTGCCTCTTAGGTCTGTGACAGAGAGTGTGTCTCCATTCCTCAGTTCCCAGAAAGGGGAGAGGTTTGG CCTAAAAAGCATGTAGATGGGGGAGAAATGGGTGGGGGGAGAGGAACAGCCATTAACACAGTATCATGTTTAACAAGTATAGCCTTGATT TCAGTAGATGTAATGGAAGCCAAATTAAATTGATACAGAACCCATTTCTCAGAGTCTTTTTTTTTTTTTGAGACAGAGTCTCGCTGTTAC CCAGGCTGGAGTGCAATGGCGCAAACTTGGCTCACTGCAACCTCTGCCCCCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCGAGTAG CTGAGACTACAGGCACCTGCCACCATACCCAGCTAAGTTATGTATTTTTAGTAGAGATGGAGTTTCACCATGTTGGCCAGGCTGGTCTCA AACTCCTGACCTCAGGTGATCCACCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGTCATTGCTCCCAGCCATTAGAAAGAT TGTTAATCCTATGAACTCCCTTTTGTAGGAGAGAAAGGGCCAATCTGTAGGGGTAGCCCTGTCCAGGTAAAGTTGTTTTCAGCCTCATGT CTACTGTTAGGTGAGGGAGTCACAGCCAGACAGAGAGTATTGCTGGAGGGTGAGAGAATTGTGGAGACCAACTACCACATAGCAAGAGCC CAGCTCTTGGGAGCATTGAGATGTAAGCTCAGGGTTACACAGTTCCAAATCTTGGGAAGGGGCTTTTCAGACAGACTGTTTGCTTTCTGC |
Top |
FusionGenePPI for RBL1_NDRG3 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| RBL1 | RBBP8, BEGAIN, BRCA1, MYBL2, CDKN1C, SUV39H1, HDAC1, HDAC2, HDAC3, ARID4A, CCNE1, CDK2, E2F5, KDM5A, AATF, SMAD3, SMAD4, E2F4, SNW1, MCM7, CCNA2, E2F1, PPP2R3A, CREG1, CCNA1, TFDP1, TFDP2, RBBP9, TAF1, BRF1, PHB, USP4, MYC, EMD, RBL2, IRF3, MAPK6, E2F3, LIN37, LIN9, LIN54, SMARCA4, TOP1, E2F2, RINT1, ID2, DGKZ, CDK4, CDK6, SP1, GOLGA2, SNRPD3, AOX1, EPHA2, FN1, NR4A1, LAMB2, NUCB1, PLSCR1, MAGEA11, AR, DYRK1A, DYRK1B, TXNDC11, CTBP1, C3orf62, NTRK1, FOXK1, FOXO3, TSC22D2, KIAA0430, HELZ | NDRG3 | ELAVL1, LACTB2, LAGE3, CPLX1, PICK1, CSTF1, GARS, NPEPL1, TARDBP, FXYD1, TUSC3, TRIM25 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
RelatedDrugs for RBL1_NDRG3 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for RBL1_NDRG3 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
|