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Fusion gene ID: 30562 |
FusionGeneSummary for RASSF3_GYS2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: RASSF3_GYS2 | Fusion gene ID: 30562 | Hgene | Tgene | Gene symbol | RASSF3 | GYS2 | Gene ID | 283349 | 2998 |
| Gene name | Ras association domain family member 3 | glycogen synthase 2 | |
| Synonyms | RASSF5 | - | |
| Cytomap | 12q14.2 | 12p12.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | ras association domain-containing protein 3Ras association (RalGDS/AF-6) domain family 3Ras association (RalGDS/AF-6) domain family member 3 | glycogen [starch] synthase, liverglycogen synthase 2 (liver) | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | Q86WH2 | P54840 | |
| Ensembl transtripts involved in fusion gene | ENST00000336061, ENST00000542104, ENST00000540088, | ENST00000261195, | |
| Fusion gene scores | * DoF score | 11 X 5 X 11=605 | 7 X 5 X 5=175 |
| # samples | 13 | 7 | |
| ** MAII score | log2(13/605*10)=-2.2184235191335 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(7/175*10)=-1.32192809488736 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: RASSF3 [Title/Abstract] AND GYS2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Oncogene involved fusion gene, in-frame and retained their domain. Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. Tumor suppressor gene involved fusion gene, retained protein feature but frameshift. DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | GYS2 | GO:0005978 | glycogen biosynthetic process | 1731614 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | PRAD | TCGA-V1-A8WL-01A | RASSF3 | chr12 | 65004523 | + | GYS2 | chr12 | 21733457 | - |
| TCGA | LD | PRAD | TCGA-V1-A8WL-01A | RASSF3 | chr12 | 65004523 | + | GYS2 | chr12 | 21728991 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000336061 | ENST00000261195 | RASSF3 | chr12 | 65004523 | + | GYS2 | chr12 | 21733457 | - |
| Frame-shift | ENST00000542104 | ENST00000261195 | RASSF3 | chr12 | 65004523 | + | GYS2 | chr12 | 21733457 | - |
| 3UTR-3CDS | ENST00000540088 | ENST00000261195 | RASSF3 | chr12 | 65004523 | + | GYS2 | chr12 | 21733457 | - |
| In-frame | ENST00000336061 | ENST00000261195 | RASSF3 | chr12 | 65004523 | + | GYS2 | chr12 | 21728991 | - |
| In-frame | ENST00000542104 | ENST00000261195 | RASSF3 | chr12 | 65004523 | + | GYS2 | chr12 | 21728991 | - |
| 3UTR-3CDS | ENST00000540088 | ENST00000261195 | RASSF3 | chr12 | 65004523 | + | GYS2 | chr12 | 21728991 | - |
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FusionProtFeatures for RASSF3_GYS2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| RASSF3 | GYS2 |
| Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >RASSF3 | chr12:65004523 | chr12:21728991 | ENST00000336061 | + | 2 | 6 | 187_234 | 37 | 239 | Domain | SARAH |
| Hgene | >RASSF3 | chr12:65004523 | chr12:21728991 | ENST00000336061 | + | 2 | 6 | 79_186 | 37 | 239 | Domain | Ras-associating |
| Hgene | >RASSF3 | chr12:65004523 | chr12:21728991 | ENST00000542104 | + | 1 | 5 | 187_234 | 37 | 239 | Domain | SARAH |
| Hgene | >RASSF3 | chr12:65004523 | chr12:21728991 | ENST00000542104 | + | 1 | 5 | 79_186 | 37 | 239 | Domain | Ras-associating |
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FusionGeneSequence for RASSF3_GYS2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_RASSF3_ENST00000336061_chr12_65004523_+_GYS2_ENST00000261195_chr12_21728991_-_640aa MSSGYSSLEEDAEDFFFTARTSFFRRAPQGKPRSGQQVHFGRWLIEGSPYVVLFDIGYSAWNLDRWKGDLWEACSVGIPYHDREANDMLI FGSLTAWFLKEVTDHADGKYVVAQFHEWQAGIGLILSRARKLPIATIFTTHATLLGRYLCAANIDFYNHLDKFNIDKEAGERQIYHRYCM ERASVHCAHVFTTVSEITAIEAEHMLKRKPDVVTPNGLNVKKFSAVHEFQNLHAMYKARIQDFVRGHFYGHLDFDLEKTLFLFIAGRYEF SNKGADIFLESLSRLNFLLRMHKSDITVMVFFIMPAKTNNFNVETLKGQAVRKQLWDVAHSVKEKFGKKLYDALLRGEIPDLNDILDRDD LTIMKRAIFSTQRQSLPPVTTHNMIDDSTDPILSTIRRIGLFNNRTDRVKVILHPEFLSSTSPLLPMDYEEFVRGCHLGVFPSYYEPWGY TPAECTVMGIPSVTTNLSGFGCFMQEHVADPTAYGIYIVDRRFRSPDDSCNQLTKFLYGFCKQSRRQRIIQRNRTERLSDLLDWRYLGRY YQHARHLTLSRAFPDKFHVELTSPPTTEGFKYPRPSSVPPSPSGSQASSPQSSDVEDEVEDERYDEEEEAERDRLNIKSPFSLSHVPHGK >In-frame_RASSF3_ENST00000542104_chr12_65004523_+_GYS2_ENST00000261195_chr12_21728991_-_640aa MSSGYSSLEEDAEDFFFTARTSFFRRAPQGKPRSGQQVHFGRWLIEGSPYVVLFDIGYSAWNLDRWKGDLWEACSVGIPYHDREANDMLI FGSLTAWFLKEVTDHADGKYVVAQFHEWQAGIGLILSRARKLPIATIFTTHATLLGRYLCAANIDFYNHLDKFNIDKEAGERQIYHRYCM ERASVHCAHVFTTVSEITAIEAEHMLKRKPDVVTPNGLNVKKFSAVHEFQNLHAMYKARIQDFVRGHFYGHLDFDLEKTLFLFIAGRYEF SNKGADIFLESLSRLNFLLRMHKSDITVMVFFIMPAKTNNFNVETLKGQAVRKQLWDVAHSVKEKFGKKLYDALLRGEIPDLNDILDRDD LTIMKRAIFSTQRQSLPPVTTHNMIDDSTDPILSTIRRIGLFNNRTDRVKVILHPEFLSSTSPLLPMDYEEFVRGCHLGVFPSYYEPWGY TPAECTVMGIPSVTTNLSGFGCFMQEHVADPTAYGIYIVDRRFRSPDDSCNQLTKFLYGFCKQSRRQRIIQRNRTERLSDLLDWRYLGRY YQHARHLTLSRAFPDKFHVELTSPPTTEGFKYPRPSSVPPSPSGSQASSPQSSDVEDEVEDERYDEEEEAERDRLNIKSPFSLSHVPHGK |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_RASSF3_ENST00000336061_chr12_65004523_+_GYS2_ENST00000261195_chr12_21728991_-_1920nt ATGAGCAGCGGCTACAGCAGCCTGGAGGAGGACGCCGAGGACTTCTTCTTCACCGCCAGGACCTCCTTCTTCAGGAGAGCGCCCCAGGGC AAGCCCCGCTCCGGCCAACAAGTGCATTTTGGAAGATGGCTGATAGAAGGAAGTCCTTATGTGGTACTTTTTGACATAGGCTATTCAGCT TGGAATCTGGACAGGTGGAAGGGTGACCTCTGGGAAGCATGCAGTGTCGGCATTCCTTATCATGACCGAGAAGCCAATGATATGCTGATA TTTGGATCTTTAACTGCCTGGTTCTTAAAAGAGGTGACAGATCATGCAGATGGTAAATATGTCGTTGCCCAATTCCATGAATGGCAGGCT GGAATTGGACTGATCCTTTCTCGAGCCAGGAAACTTCCTATTGCCACAATATTTACAACCCACGCTACACTACTTGGGAGGTATCTCTGT GCAGCAAATATTGATTTCTACAACCATCTTGATAAGTTTAACATTGACAAAGAGGCTGGGGAAAGGCAGATTTACCACCGGTACTGCATG GAGCGAGCTTCCGTTCATTGCGCTCACGTGTTCACCACGGTTTCTGAAATAACAGCAATAGAAGCTGAACATATGCTGAAGAGAAAGCCT GATGTAGTTACTCCAAACGGCTTGAATGTTAAGAAATTTTCAGCAGTGCATGAGTTTCAAAATCTACATGCCATGTACAAGGCCAGAATC CAAGATTTTGTTCGAGGTCATTTCTATGGTCATCTCGACTTTGATCTTGAAAAGACTTTGTTCCTTTTCATTGCTGGGAGGTATGAGTTT TCAAACAAAGGAGCTGACATCTTCCTAGAATCCTTATCCAGGCTAAATTTCCTGCTGAGGATGCATAAAAGTGACATCACAGTGATGGTG TTTTTCATTATGCCTGCCAAGACAAATAATTTCAACGTGGAAACCCTGAAAGGACAAGCAGTGCGAAAACAGCTGTGGGATGTTGCACAT TCTGTGAAGGAAAAGTTTGGAAAAAAACTCTATGATGCATTATTAAGAGGAGAAATTCCTGACCTGAACGATATTTTAGATCGAGATGAT CTAACAATTATGAAAAGAGCCATCTTTTCAACTCAGCGACAGTCATTGCCCCCAGTGACCACGCACAACATGATTGATGACTCCACCGAC CCCATCCTCAGCACCATTAGACGGATTGGACTTTTCAACAACCGCACAGATAGAGTCAAGGTGATTTTGCACCCAGAGTTTCTATCCTCC ACCAGTCCCTTACTACCCATGGACTATGAAGAGTTTGTTAGAGGTTGTCATCTTGGAGTATTTCCATCATACTATGAACCCTGGGGTTAT ACTCCAGCTGAATGCACTGTGATGGGTATCCCCAGTGTGACCACGAATCTCTCCGGGTTTGGCTGTTTCATGCAGGAGCACGTGGCTGAT CCTACTGCTTACGGTATTTACATCGTTGACAGGCGGTTCCGTTCTCCAGATGATTCTTGCAATCAGCTGACTAAGTTTCTCTATGGATTT TGCAAACAGTCACGCCGCCAAAGGATTATCCAGAGGAACAGAACTGAGAGGCTCTCAGATCTTCTGGATTGGAGATACTTAGGCAGATAT TACCAGCATGCCAGACACCTGACATTAAGCAGAGCTTTTCCAGATAAATTCCATGTGGAACTAACATCACCACCAACGACAGAAGGATTT AAATATCCCAGGCCTTCCTCAGTACCACCTTCTCCTTCAGGGTCTCAGGCCTCCAGTCCTCAGAGCAGTGATGTGGAAGATGAAGTGGAG GATGAGAGATACGATGAGGAAGAGGAGGCTGAAAGGGATCGGTTAAATATCAAGTCACCATTTTCACTGAGCCACGTTCCTCATGGGAAG >In-frame_RASSF3_ENST00000542104_chr12_65004523_+_GYS2_ENST00000261195_chr12_21728991_-_1920nt ATGAGCAGCGGCTACAGCAGCCTGGAGGAGGACGCCGAGGACTTCTTCTTCACCGCCAGGACCTCCTTCTTCAGGAGAGCGCCCCAGGGC AAGCCCCGCTCCGGCCAACAAGTGCATTTTGGAAGATGGCTGATAGAAGGAAGTCCTTATGTGGTACTTTTTGACATAGGCTATTCAGCT TGGAATCTGGACAGGTGGAAGGGTGACCTCTGGGAAGCATGCAGTGTCGGCATTCCTTATCATGACCGAGAAGCCAATGATATGCTGATA TTTGGATCTTTAACTGCCTGGTTCTTAAAAGAGGTGACAGATCATGCAGATGGTAAATATGTCGTTGCCCAATTCCATGAATGGCAGGCT GGAATTGGACTGATCCTTTCTCGAGCCAGGAAACTTCCTATTGCCACAATATTTACAACCCACGCTACACTACTTGGGAGGTATCTCTGT GCAGCAAATATTGATTTCTACAACCATCTTGATAAGTTTAACATTGACAAAGAGGCTGGGGAAAGGCAGATTTACCACCGGTACTGCATG GAGCGAGCTTCCGTTCATTGCGCTCACGTGTTCACCACGGTTTCTGAAATAACAGCAATAGAAGCTGAACATATGCTGAAGAGAAAGCCT GATGTAGTTACTCCAAACGGCTTGAATGTTAAGAAATTTTCAGCAGTGCATGAGTTTCAAAATCTACATGCCATGTACAAGGCCAGAATC CAAGATTTTGTTCGAGGTCATTTCTATGGTCATCTCGACTTTGATCTTGAAAAGACTTTGTTCCTTTTCATTGCTGGGAGGTATGAGTTT TCAAACAAAGGAGCTGACATCTTCCTAGAATCCTTATCCAGGCTAAATTTCCTGCTGAGGATGCATAAAAGTGACATCACAGTGATGGTG TTTTTCATTATGCCTGCCAAGACAAATAATTTCAACGTGGAAACCCTGAAAGGACAAGCAGTGCGAAAACAGCTGTGGGATGTTGCACAT TCTGTGAAGGAAAAGTTTGGAAAAAAACTCTATGATGCATTATTAAGAGGAGAAATTCCTGACCTGAACGATATTTTAGATCGAGATGAT CTAACAATTATGAAAAGAGCCATCTTTTCAACTCAGCGACAGTCATTGCCCCCAGTGACCACGCACAACATGATTGATGACTCCACCGAC CCCATCCTCAGCACCATTAGACGGATTGGACTTTTCAACAACCGCACAGATAGAGTCAAGGTGATTTTGCACCCAGAGTTTCTATCCTCC ACCAGTCCCTTACTACCCATGGACTATGAAGAGTTTGTTAGAGGTTGTCATCTTGGAGTATTTCCATCATACTATGAACCCTGGGGTTAT ACTCCAGCTGAATGCACTGTGATGGGTATCCCCAGTGTGACCACGAATCTCTCCGGGTTTGGCTGTTTCATGCAGGAGCACGTGGCTGAT CCTACTGCTTACGGTATTTACATCGTTGACAGGCGGTTCCGTTCTCCAGATGATTCTTGCAATCAGCTGACTAAGTTTCTCTATGGATTT TGCAAACAGTCACGCCGCCAAAGGATTATCCAGAGGAACAGAACTGAGAGGCTCTCAGATCTTCTGGATTGGAGATACTTAGGCAGATAT TACCAGCATGCCAGACACCTGACATTAAGCAGAGCTTTTCCAGATAAATTCCATGTGGAACTAACATCACCACCAACGACAGAAGGATTT AAATATCCCAGGCCTTCCTCAGTACCACCTTCTCCTTCAGGGTCTCAGGCCTCCAGTCCTCAGAGCAGTGATGTGGAAGATGAAGTGGAG GATGAGAGATACGATGAGGAAGAGGAGGCTGAAAGGGATCGGTTAAATATCAAGTCACCATTTTCACTGAGCCACGTTCCTCATGGGAAG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_RASSF3_ENST00000336061_chr12_65004523_+_GYS2_ENST00000261195_chr12_21728991_-_2728nt GCTGCATAAGGACTGCCCGGGGCTGCGCGACGGGACCGGCAGCATGAGCAGCGGCTACAGCAGCCTGGAGGAGGACGCCGAGGACTTCTT CTTCACCGCCAGGACCTCCTTCTTCAGGAGAGCGCCCCAGGGCAAGCCCCGCTCCGGCCAACAAGTGCATTTTGGAAGATGGCTGATAGA AGGAAGTCCTTATGTGGTACTTTTTGACATAGGCTATTCAGCTTGGAATCTGGACAGGTGGAAGGGTGACCTCTGGGAAGCATGCAGTGT CGGCATTCCTTATCATGACCGAGAAGCCAATGATATGCTGATATTTGGATCTTTAACTGCCTGGTTCTTAAAAGAGGTGACAGATCATGC AGATGGTAAATATGTCGTTGCCCAATTCCATGAATGGCAGGCTGGAATTGGACTGATCCTTTCTCGAGCCAGGAAACTTCCTATTGCCAC AATATTTACAACCCACGCTACACTACTTGGGAGGTATCTCTGTGCAGCAAATATTGATTTCTACAACCATCTTGATAAGTTTAACATTGA CAAAGAGGCTGGGGAAAGGCAGATTTACCACCGGTACTGCATGGAGCGAGCTTCCGTTCATTGCGCTCACGTGTTCACCACGGTTTCTGA AATAACAGCAATAGAAGCTGAACATATGCTGAAGAGAAAGCCTGATGTAGTTACTCCAAACGGCTTGAATGTTAAGAAATTTTCAGCAGT GCATGAGTTTCAAAATCTACATGCCATGTACAAGGCCAGAATCCAAGATTTTGTTCGAGGTCATTTCTATGGTCATCTCGACTTTGATCT TGAAAAGACTTTGTTCCTTTTCATTGCTGGGAGGTATGAGTTTTCAAACAAAGGAGCTGACATCTTCCTAGAATCCTTATCCAGGCTAAA TTTCCTGCTGAGGATGCATAAAAGTGACATCACAGTGATGGTGTTTTTCATTATGCCTGCCAAGACAAATAATTTCAACGTGGAAACCCT GAAAGGACAAGCAGTGCGAAAACAGCTGTGGGATGTTGCACATTCTGTGAAGGAAAAGTTTGGAAAAAAACTCTATGATGCATTATTAAG AGGAGAAATTCCTGACCTGAACGATATTTTAGATCGAGATGATCTAACAATTATGAAAAGAGCCATCTTTTCAACTCAGCGACAGTCATT GCCCCCAGTGACCACGCACAACATGATTGATGACTCCACCGACCCCATCCTCAGCACCATTAGACGGATTGGACTTTTCAACAACCGCAC AGATAGAGTCAAGGTGATTTTGCACCCAGAGTTTCTATCCTCCACCAGTCCCTTACTACCCATGGACTATGAAGAGTTTGTTAGAGGTTG TCATCTTGGAGTATTTCCATCATACTATGAACCCTGGGGTTATACTCCAGCTGAATGCACTGTGATGGGTATCCCCAGTGTGACCACGAA TCTCTCCGGGTTTGGCTGTTTCATGCAGGAGCACGTGGCTGATCCTACTGCTTACGGTATTTACATCGTTGACAGGCGGTTCCGTTCTCC AGATGATTCTTGCAATCAGCTGACTAAGTTTCTCTATGGATTTTGCAAACAGTCACGCCGCCAAAGGATTATCCAGAGGAACAGAACTGA GAGGCTCTCAGATCTTCTGGATTGGAGATACTTAGGCAGATATTACCAGCATGCCAGACACCTGACATTAAGCAGAGCTTTTCCAGATAA ATTCCATGTGGAACTAACATCACCACCAACGACAGAAGGATTTAAATATCCCAGGCCTTCCTCAGTACCACCTTCTCCTTCAGGGTCTCA GGCCTCCAGTCCTCAGAGCAGTGATGTGGAAGATGAAGTGGAGGATGAGAGATACGATGAGGAAGAGGAGGCTGAAAGGGATCGGTTAAA TATCAAGTCACCATTTTCACTGAGCCACGTTCCTCATGGGAAGAAAAAGCTGCATGGTGAATATAAGAACTGAATTCTACATGTGCTGCA TGAAGAGCTAATTTAAAAAAGCAAAGTAAGACTAATTATTTAAAATAAAAATGCCACAAATTTCATTTTCTCCTTCTAAGTATTACAATG GAGTTTATTCTCTGCCTAAAAAGTGGAAGAAATTGAGTGAATGACAATTTTGTAATTTAGGATAAGATCCAAGTTATTTTCCCCAACTCT TGTTTCCCCCATAAAGTTAGGCATGAGGAGGAGCACTCATTAAAGGCAGAAGACGGAAAAGTGTTTTTAAAATGGTGAATTTAAGTGGTA AGGATTTTCTCTTACTCTGTTTATTTTTAAATGATCATCATAATCCTTTGCTTACTATTTATGCAGCTTCTCTACCCCACCACACAAATT TCCCATTTCCCCCCCGAAAACCTTGATCTTACCCATGAATGTGCACTACCTACATTTTTTAAATAGCTAGGTTTTTACTGATTATTTTCA TTTTTCACATGCATCAGAACCATGATTTAGATGTAGTTTTGCAGAGACAAAAATCCATGAGTGAATAGCTATCCTAAGTCCATATTTTGA TGCATATTAATGGACATTTATGTCACTTTTGAAATCTAGAATTGATGTTGTAATTAATGCAAGATATTACCATGTACATGGTACCACCAT CTTACTGTAACATTTTTCTATTGTTTAAATAGAAAGCCTTTTTAAAATTTGGTCAATCTTCATAGATGATAACTTGTAAAATCCAAGTAA >In-frame_RASSF3_ENST00000542104_chr12_65004523_+_GYS2_ENST00000261195_chr12_21728991_-_2805nt GCTGCATAAGGACTGCCCGGGGCTGCGCGCCGGGAACCTCGCGGGGCTGGCGGGCGCCGCACCCCCTCCCTGGCCGCCTGCGCCCCGGGG AGGCCGCCCGCGCGCGACGGGACCGGCAGCATGAGCAGCGGCTACAGCAGCCTGGAGGAGGACGCCGAGGACTTCTTCTTCACCGCCAGG ACCTCCTTCTTCAGGAGAGCGCCCCAGGGCAAGCCCCGCTCCGGCCAACAAGTGCATTTTGGAAGATGGCTGATAGAAGGAAGTCCTTAT GTGGTACTTTTTGACATAGGCTATTCAGCTTGGAATCTGGACAGGTGGAAGGGTGACCTCTGGGAAGCATGCAGTGTCGGCATTCCTTAT CATGACCGAGAAGCCAATGATATGCTGATATTTGGATCTTTAACTGCCTGGTTCTTAAAAGAGGTGACAGATCATGCAGATGGTAAATAT GTCGTTGCCCAATTCCATGAATGGCAGGCTGGAATTGGACTGATCCTTTCTCGAGCCAGGAAACTTCCTATTGCCACAATATTTACAACC CACGCTACACTACTTGGGAGGTATCTCTGTGCAGCAAATATTGATTTCTACAACCATCTTGATAAGTTTAACATTGACAAAGAGGCTGGG GAAAGGCAGATTTACCACCGGTACTGCATGGAGCGAGCTTCCGTTCATTGCGCTCACGTGTTCACCACGGTTTCTGAAATAACAGCAATA GAAGCTGAACATATGCTGAAGAGAAAGCCTGATGTAGTTACTCCAAACGGCTTGAATGTTAAGAAATTTTCAGCAGTGCATGAGTTTCAA AATCTACATGCCATGTACAAGGCCAGAATCCAAGATTTTGTTCGAGGTCATTTCTATGGTCATCTCGACTTTGATCTTGAAAAGACTTTG TTCCTTTTCATTGCTGGGAGGTATGAGTTTTCAAACAAAGGAGCTGACATCTTCCTAGAATCCTTATCCAGGCTAAATTTCCTGCTGAGG ATGCATAAAAGTGACATCACAGTGATGGTGTTTTTCATTATGCCTGCCAAGACAAATAATTTCAACGTGGAAACCCTGAAAGGACAAGCA GTGCGAAAACAGCTGTGGGATGTTGCACATTCTGTGAAGGAAAAGTTTGGAAAAAAACTCTATGATGCATTATTAAGAGGAGAAATTCCT GACCTGAACGATATTTTAGATCGAGATGATCTAACAATTATGAAAAGAGCCATCTTTTCAACTCAGCGACAGTCATTGCCCCCAGTGACC ACGCACAACATGATTGATGACTCCACCGACCCCATCCTCAGCACCATTAGACGGATTGGACTTTTCAACAACCGCACAGATAGAGTCAAG GTGATTTTGCACCCAGAGTTTCTATCCTCCACCAGTCCCTTACTACCCATGGACTATGAAGAGTTTGTTAGAGGTTGTCATCTTGGAGTA TTTCCATCATACTATGAACCCTGGGGTTATACTCCAGCTGAATGCACTGTGATGGGTATCCCCAGTGTGACCACGAATCTCTCCGGGTTT GGCTGTTTCATGCAGGAGCACGTGGCTGATCCTACTGCTTACGGTATTTACATCGTTGACAGGCGGTTCCGTTCTCCAGATGATTCTTGC AATCAGCTGACTAAGTTTCTCTATGGATTTTGCAAACAGTCACGCCGCCAAAGGATTATCCAGAGGAACAGAACTGAGAGGCTCTCAGAT CTTCTGGATTGGAGATACTTAGGCAGATATTACCAGCATGCCAGACACCTGACATTAAGCAGAGCTTTTCCAGATAAATTCCATGTGGAA CTAACATCACCACCAACGACAGAAGGATTTAAATATCCCAGGCCTTCCTCAGTACCACCTTCTCCTTCAGGGTCTCAGGCCTCCAGTCCT CAGAGCAGTGATGTGGAAGATGAAGTGGAGGATGAGAGATACGATGAGGAAGAGGAGGCTGAAAGGGATCGGTTAAATATCAAGTCACCA TTTTCACTGAGCCACGTTCCTCATGGGAAGAAAAAGCTGCATGGTGAATATAAGAACTGAATTCTACATGTGCTGCATGAAGAGCTAATT TAAAAAAGCAAAGTAAGACTAATTATTTAAAATAAAAATGCCACAAATTTCATTTTCTCCTTCTAAGTATTACAATGGAGTTTATTCTCT GCCTAAAAAGTGGAAGAAATTGAGTGAATGACAATTTTGTAATTTAGGATAAGATCCAAGTTATTTTCCCCAACTCTTGTTTCCCCCATA AAGTTAGGCATGAGGAGGAGCACTCATTAAAGGCAGAAGACGGAAAAGTGTTTTTAAAATGGTGAATTTAAGTGGTAAGGATTTTCTCTT ACTCTGTTTATTTTTAAATGATCATCATAATCCTTTGCTTACTATTTATGCAGCTTCTCTACCCCACCACACAAATTTCCCATTTCCCCC CCGAAAACCTTGATCTTACCCATGAATGTGCACTACCTACATTTTTTAAATAGCTAGGTTTTTACTGATTATTTTCATTTTTCACATGCA TCAGAACCATGATTTAGATGTAGTTTTGCAGAGACAAAAATCCATGAGTGAATAGCTATCCTAAGTCCATATTTTGATGCATATTAATGG ACATTTATGTCACTTTTGAAATCTAGAATTGATGTTGTAATTAATGCAAGATATTACCATGTACATGGTACCACCATCTTACTGTAACAT TTTTCTATTGTTTAAATAGAAAGCCTTTTTAAAATTTGGTCAATCTTCATAGATGATAACTTGTAAAATCCAAGTAAATAAACACATTAA 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FusionGenePPI for RASSF3_GYS2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| RASSF3 | MDM2, APP, STK3, STK4, FBXW11, BTRC, MAP1S, CDC37, FGFR1OP2, MAP1B, MOB4, SIKE1, SLMAP, STRN, STRN3, STRN4, STRIP1, VAPA, VAPB, XPO1, LITAF | GYS2 | TNFRSF1A, GYG2, PPP1R3B, PPP1R3C, PPP1CA, STBD1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for RASSF3_GYS2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for RASSF3_GYS2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | GYS2 | C1855861 | Glycogen Storage Disease 0, Liver | 1 | CTD_human;ORPHANET;UNIPROT |
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