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Fusion gene ID: 30529 |
FusionGeneSummary for RASAL2_COPA |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: RASAL2_COPA | Fusion gene ID: 30529 | Hgene | Tgene | Gene symbol | RASAL2 | COPA | Gene ID | 9462 | 1314 |
| Gene name | RAS protein activator like 2 | coatomer protein complex subunit alpha | |
| Synonyms | NGAP | AILJK|HEP-COP | |
| Cytomap | 1q25.2 | 1q23.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | ras GTPase-activating protein nGAPRASAL2/ACVR1 fusionRas protein activator like 1 | coatomer subunit alphaHEPCOPalpha coat proteinalpha-COPproxeninxenin | |
| Modification date | 20180522 | 20180523 | |
| UniProtAcc | Q9UJF2 | P53621 | |
| Ensembl transtripts involved in fusion gene | ENST00000448150, ENST00000367649, ENST00000465723, ENST00000462775, | ENST00000368069, ENST00000241704, | |
| Fusion gene scores | * DoF score | 12 X 8 X 8=768 | 9 X 11 X 5=495 |
| # samples | 13 | 10 | |
| ** MAII score | log2(13/768*10)=-2.5625946876927 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(10/495*10)=-2.30742852519225 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: RASAL2 [Title/Abstract] AND COPA [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | COPA | GO:0030157 | pancreatic juice secretion | 1429581 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | CHOL | TCGA-4G-AAZO-01A | RASAL2 | chr1 | 178269253 | + | COPA | chr1 | 160310084 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000448150 | ENST00000368069 | RASAL2 | chr1 | 178269253 | + | COPA | chr1 | 160310084 | - |
| In-frame | ENST00000448150 | ENST00000241704 | RASAL2 | chr1 | 178269253 | + | COPA | chr1 | 160310084 | - |
| In-frame | ENST00000367649 | ENST00000368069 | RASAL2 | chr1 | 178269253 | + | COPA | chr1 | 160310084 | - |
| In-frame | ENST00000367649 | ENST00000241704 | RASAL2 | chr1 | 178269253 | + | COPA | chr1 | 160310084 | - |
| intron-3CDS | ENST00000465723 | ENST00000368069 | RASAL2 | chr1 | 178269253 | + | COPA | chr1 | 160310084 | - |
| intron-3CDS | ENST00000465723 | ENST00000241704 | RASAL2 | chr1 | 178269253 | + | COPA | chr1 | 160310084 | - |
| intron-3CDS | ENST00000462775 | ENST00000368069 | RASAL2 | chr1 | 178269253 | + | COPA | chr1 | 160310084 | - |
| intron-3CDS | ENST00000462775 | ENST00000241704 | RASAL2 | chr1 | 178269253 | + | COPA | chr1 | 160310084 | - |
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FusionProtFeatures for RASAL2_COPA |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| RASAL2 | COPA |
| Inhibitory regulator of the Ras-cyclic AMP pathway. | The coatomer is a cytosolic protein complex that bindsto dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosyntheticprotein transport from the ER, via the Golgi up to the trans Golginetwork. Coatomer complex is required for budding from Golgimembranes, and is essential for the retrograde Golgi-to-ERtransport of dilysine-tagged proteins. In mammals, the coatomercan only be recruited by membranes associated to ADP-ribosylationfactors (ARFs), which are small GTP-binding proteins; the complexalso influences the Golgi structural integrity, as well as theprocessing, activity, and endocytic recycling of LDL receptors (Bysimilarity). {ECO:0000250}. Xenin stimulates exocrine pancreatic secretion. Itinhibits pentagastrin-stimulated secretion of acid, to induceexocrine pancreatic secretion and to affect small and largeintestinal motility. In the gut, xenin interacts with theneurotensin receptor. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >COPA | chr1:178269253 | chr1:160310084 | ENST00000241704 | - | 0 | 33 | 126_164 | 13 | 1225 | Repeat | Note=WD 4 |
| Tgene | >COPA | chr1:178269253 | chr1:160310084 | ENST00000241704 | - | 0 | 33 | 195_234 | 13 | 1225 | Repeat | Note=WD 5 |
| Tgene | >COPA | chr1:178269253 | chr1:160310084 | ENST00000241704 | - | 0 | 33 | 241_278 | 13 | 1225 | Repeat | Note=WD 6 |
| Tgene | >COPA | chr1:178269253 | chr1:160310084 | ENST00000241704 | - | 0 | 33 | 282_319 | 13 | 1225 | Repeat | Note=WD 7 |
| Tgene | >COPA | chr1:178269253 | chr1:160310084 | ENST00000241704 | - | 0 | 33 | 42_80 | 13 | 1225 | Repeat | Note=WD 2 |
| Tgene | >COPA | chr1:178269253 | chr1:160310084 | ENST00000241704 | - | 0 | 33 | 84_122 | 13 | 1225 | Repeat | Note=WD 3 |
| Tgene | >COPA | chr1:178269253 | chr1:160310084 | ENST00000368069 | - | 0 | 33 | 126_164 | 13 | 1234 | Repeat | Note=WD 4 |
| Tgene | >COPA | chr1:178269253 | chr1:160310084 | ENST00000368069 | - | 0 | 33 | 195_234 | 13 | 1234 | Repeat | Note=WD 5 |
| Tgene | >COPA | chr1:178269253 | chr1:160310084 | ENST00000368069 | - | 0 | 33 | 241_278 | 13 | 1234 | Repeat | Note=WD 6 |
| Tgene | >COPA | chr1:178269253 | chr1:160310084 | ENST00000368069 | - | 0 | 33 | 282_319 | 13 | 1234 | Repeat | Note=WD 7 |
| Tgene | >COPA | chr1:178269253 | chr1:160310084 | ENST00000368069 | - | 0 | 33 | 42_80 | 13 | 1234 | Repeat | Note=WD 2 |
| Tgene | >COPA | chr1:178269253 | chr1:160310084 | ENST00000368069 | - | 0 | 33 | 84_122 | 13 | 1234 | Repeat | Note=WD 3 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >RASAL2 | chr1:178269253 | chr1:160310084 | ENST00000367649 | + | 3 | 18 | 237_243 | 152 | 1281 | Compositional bias | Note=Poly-Lys |
| Hgene | >RASAL2 | chr1:178269253 | chr1:160310084 | ENST00000367649 | + | 3 | 18 | 922_925 | 152 | 1281 | Compositional bias | Note=Poly-Ser |
| Hgene | >RASAL2 | chr1:178269253 | chr1:160310084 | ENST00000462775 | + | 1 | 16 | 237_243 | -42 | 1140 | Compositional bias | Note=Poly-Lys |
| Hgene | >RASAL2 | chr1:178269253 | chr1:160310084 | ENST00000462775 | + | 1 | 16 | 922_925 | -42 | 1140 | Compositional bias | Note=Poly-Ser |
| Hgene | >RASAL2 | chr1:178269253 | chr1:160310084 | ENST00000367649 | + | 3 | 18 | 170_266 | 152 | 1281 | Domain | Note=C2 |
| Hgene | >RASAL2 | chr1:178269253 | chr1:160310084 | ENST00000367649 | + | 3 | 18 | 327_519 | 152 | 1281 | Domain | Ras-GAP |
| Hgene | >RASAL2 | chr1:178269253 | chr1:160310084 | ENST00000367649 | + | 3 | 18 | 41_158 | 152 | 1281 | Domain | Note=PH |
| Hgene | >RASAL2 | chr1:178269253 | chr1:160310084 | ENST00000462775 | + | 1 | 16 | 170_266 | -42 | 1140 | Domain | Note=C2 |
| Hgene | >RASAL2 | chr1:178269253 | chr1:160310084 | ENST00000462775 | + | 1 | 16 | 327_519 | -42 | 1140 | Domain | Ras-GAP |
| Hgene | >RASAL2 | chr1:178269253 | chr1:160310084 | ENST00000462775 | + | 1 | 16 | 41_158 | -42 | 1140 | Domain | Note=PH |
| Tgene | COPA | chr1:178269253 | chr1:160310084 | ENST00000241704 | - | 0 | 33 | 3_38 | 13 | 1225 | Repeat | Note=WD 1 |
| Tgene | COPA | chr1:178269253 | chr1:160310084 | ENST00000368069 | - | 0 | 33 | 3_38 | 13 | 1234 | Repeat | Note=WD 1 |
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FusionGeneSequence for RASAL2_COPA |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_RASAL2_ENST00000448150_chr1_178269253_+_COPA_ENST00000368069_chr1_160310084_-_1355aa MFPALESDSPLPPEDLDAVVPVSGAVAGGMLDRILLESVCQQQSWVRVYDVKGPPTHRLSCGQSPYTETTTWERKYCILTDSQLVLLNKE KEIPVEGGQEQQTDSTKGRCLRRTVSVPSEGQFPEYPPEGATKLGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDF HKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPTEDL VVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITGVDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKA WEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAHPNLNLFAAGHDGGMIVFKLERERPAYAVH GNMLHYVKDRFLRQLDFNSSKDVAVMQLRSGSKFPVFNMSYNPAENAVLLCTRASNLENSTYDLYTIPKDADSQNPDAPEGKRSSGLTAV WVARNRFAVLDRMHSLLIKNLKNEITKKVQVPNCDEIFYAGTGNLLLRDADSITLFDVQQKRTLASVKISKVKYVIWSADMSHVALLAKH EHSCPLPLTAIVICNRKLDALCNIHENIRVKSGAWDESGVFIYTTSNHIKYAVTTGDHGIIRTLDLPIYVTRVKGNNVYCLDRECRPRVL TIDPTEFKFKLALINRKYDEVLHMVRNAKLVGQSIIAYLQKKGYPEVALHFVKDEKTRFSLALECGNIEIALEAAKALDDKNCWEKLGEV ALLQGNHQIVEMCYQRTKNFDKLSFLYLITGNLEKLRKMMKIAEIRKDMSGHYQNALYLGDVSERVRILKNCGQKSLAYLTAATHGLDEE AESLKETFDPEKETIPDIDPNAKLLQPPAPIMPLDTNWPLLTVSKGFFEGTIASKGKGGALAADIDIDTVGTEGWGEDAELQLDEDGFVE ATEGLGDDALGKGQEEGGGWDVEEDLELPPELDISPGAAGGAEDGFFVPPTKGTSPTQIWCNNSQLPVDHILAGSFETAMRLLHDQVGVI QFGPYKQLFLQTYARGRTTYQALPCLPSMYGYPNRNWKDAGLKNGVPAVGLKLNDLIQRLQLCYQLTTVGKFEEAVEKFRSILLSVPLLV VDNKQEIAEAQQLITICREYIVGLSVETERKKLPKETLEQQKRICEMAAYFTHSNLQPVHMILVLRTALNLFFKLKNFKTAATFARRLLE LGPKPEVAQQTRKILSACEKNPTDAYQLNYDMHNPFDICAASYRPIYRGKPVEKCPLSGACYSPEFKGQICRVTTVTEIGKDVIGLRISP >In-frame_RASAL2_ENST00000448150_chr1_178269253_+_COPA_ENST00000241704_chr1_160310084_-_1346aa MFPALESDSPLPPEDLDAVVPVSGAVAGGMLDRILLESVCQQQSWVRVYDVKGPPTHRLSCGQSPYTETTTWERKYCILTDSQLVLLNKE KEIPVEGGQEQQTDSTKGRCLRRTVSVPSEGQFPEYPPEGATKLGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDF HKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPTEDL VVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITGVDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKA WEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAHPNLNLFAAGHDGGMIVFKLERERPAYAVH GNMLHYVKDRFLRQLDFNSSKDVAVMQLRSGSKFPVFNMSYNPAENAVLLCTRASNLENSTYDLYTIPKDADSQNPDAPEGKRSSGLTAV WVARNRFAVLDRMHSLLIKNLKNEITKKVQVPNCDEIFYAGTGNLLLRDADSITLFDVQQKRTLASVKISKVKYVIWSADMSHVALLAKH AIVICNRKLDALCNIHENIRVKSGAWDESGVFIYTTSNHIKYAVTTGDHGIIRTLDLPIYVTRVKGNNVYCLDRECRPRVLTIDPTEFKF KLALINRKYDEVLHMVRNAKLVGQSIIAYLQKKGYPEVALHFVKDEKTRFSLALECGNIEIALEAAKALDDKNCWEKLGEVALLQGNHQI VEMCYQRTKNFDKLSFLYLITGNLEKLRKMMKIAEIRKDMSGHYQNALYLGDVSERVRILKNCGQKSLAYLTAATHGLDEEAESLKETFD PEKETIPDIDPNAKLLQPPAPIMPLDTNWPLLTVSKGFFEGTIASKGKGGALAADIDIDTVGTEGWGEDAELQLDEDGFVEATEGLGDDA LGKGQEEGGGWDVEEDLELPPELDISPGAAGGAEDGFFVPPTKGTSPTQIWCNNSQLPVDHILAGSFETAMRLLHDQVGVIQFGPYKQLF LQTYARGRTTYQALPCLPSMYGYPNRNWKDAGLKNGVPAVGLKLNDLIQRLQLCYQLTTVGKFEEAVEKFRSILLSVPLLVVDNKQEIAE AQQLITICREYIVGLSVETERKKLPKETLEQQKRICEMAAYFTHSNLQPVHMILVLRTALNLFFKLKNFKTAATFARRLLELGPKPEVAQ >In-frame_RASAL2_ENST00000367649_chr1_178269253_+_COPA_ENST00000368069_chr1_160310084_-_1373aa MELSPSSGGAAEALSWPEMFPALESDSPLPPEDLDAVVPVSGAVAGGMLDRILLESVCQQQSWVRVYDVKGPPTHRLSCGQSPYTETTTW ERKYCILTDSQLVLLNKEKEIPVEGGQEQQTDSTKGRCLRRTVSVPSEGQFPEYPPEGATKLGLSFHPKRPWILTSLHNGVIQLWDYRMC TLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVL TGHNHYVMCAQFHPTEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITGVDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIV SGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAHPNLNLFAAGHD GGMIVFKLERERPAYAVHGNMLHYVKDRFLRQLDFNSSKDVAVMQLRSGSKFPVFNMSYNPAENAVLLCTRASNLENSTYDLYTIPKDAD SQNPDAPEGKRSSGLTAVWVARNRFAVLDRMHSLLIKNLKNEITKKVQVPNCDEIFYAGTGNLLLRDADSITLFDVQQKRTLASVKISKV KYVIWSADMSHVALLAKHEHSCPLPLTAIVICNRKLDALCNIHENIRVKSGAWDESGVFIYTTSNHIKYAVTTGDHGIIRTLDLPIYVTR VKGNNVYCLDRECRPRVLTIDPTEFKFKLALINRKYDEVLHMVRNAKLVGQSIIAYLQKKGYPEVALHFVKDEKTRFSLALECGNIEIAL EAAKALDDKNCWEKLGEVALLQGNHQIVEMCYQRTKNFDKLSFLYLITGNLEKLRKMMKIAEIRKDMSGHYQNALYLGDVSERVRILKNC GQKSLAYLTAATHGLDEEAESLKETFDPEKETIPDIDPNAKLLQPPAPIMPLDTNWPLLTVSKGFFEGTIASKGKGGALAADIDIDTVGT EGWGEDAELQLDEDGFVEATEGLGDDALGKGQEEGGGWDVEEDLELPPELDISPGAAGGAEDGFFVPPTKGTSPTQIWCNNSQLPVDHIL AGSFETAMRLLHDQVGVIQFGPYKQLFLQTYARGRTTYQALPCLPSMYGYPNRNWKDAGLKNGVPAVGLKLNDLIQRLQLCYQLTTVGKF EEAVEKFRSILLSVPLLVVDNKQEIAEAQQLITICREYIVGLSVETERKKLPKETLEQQKRICEMAAYFTHSNLQPVHMILVLRTALNLF FKLKNFKTAATFARRLLELGPKPEVAQQTRKILSACEKNPTDAYQLNYDMHNPFDICAASYRPIYRGKPVEKCPLSGACYSPEFKGQICR >In-frame_RASAL2_ENST00000367649_chr1_178269253_+_COPA_ENST00000241704_chr1_160310084_-_1364aa MELSPSSGGAAEALSWPEMFPALESDSPLPPEDLDAVVPVSGAVAGGMLDRILLESVCQQQSWVRVYDVKGPPTHRLSCGQSPYTETTTW ERKYCILTDSQLVLLNKEKEIPVEGGQEQQTDSTKGRCLRRTVSVPSEGQFPEYPPEGATKLGLSFHPKRPWILTSLHNGVIQLWDYRMC TLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVL TGHNHYVMCAQFHPTEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITGVDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIV SGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAHPNLNLFAAGHD GGMIVFKLERERPAYAVHGNMLHYVKDRFLRQLDFNSSKDVAVMQLRSGSKFPVFNMSYNPAENAVLLCTRASNLENSTYDLYTIPKDAD SQNPDAPEGKRSSGLTAVWVARNRFAVLDRMHSLLIKNLKNEITKKVQVPNCDEIFYAGTGNLLLRDADSITLFDVQQKRTLASVKISKV KYVIWSADMSHVALLAKHAIVICNRKLDALCNIHENIRVKSGAWDESGVFIYTTSNHIKYAVTTGDHGIIRTLDLPIYVTRVKGNNVYCL DRECRPRVLTIDPTEFKFKLALINRKYDEVLHMVRNAKLVGQSIIAYLQKKGYPEVALHFVKDEKTRFSLALECGNIEIALEAAKALDDK NCWEKLGEVALLQGNHQIVEMCYQRTKNFDKLSFLYLITGNLEKLRKMMKIAEIRKDMSGHYQNALYLGDVSERVRILKNCGQKSLAYLT AATHGLDEEAESLKETFDPEKETIPDIDPNAKLLQPPAPIMPLDTNWPLLTVSKGFFEGTIASKGKGGALAADIDIDTVGTEGWGEDAEL QLDEDGFVEATEGLGDDALGKGQEEGGGWDVEEDLELPPELDISPGAAGGAEDGFFVPPTKGTSPTQIWCNNSQLPVDHILAGSFETAMR LLHDQVGVIQFGPYKQLFLQTYARGRTTYQALPCLPSMYGYPNRNWKDAGLKNGVPAVGLKLNDLIQRLQLCYQLTTVGKFEEAVEKFRS ILLSVPLLVVDNKQEIAEAQQLITICREYIVGLSVETERKKLPKETLEQQKRICEMAAYFTHSNLQPVHMILVLRTALNLFFKLKNFKTA ATFARRLLELGPKPEVAQQTRKILSACEKNPTDAYQLNYDMHNPFDICAASYRPIYRGKPVEKCPLSGACYSPEFKGQICRVTTVTEIGK |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_RASAL2_ENST00000448150_chr1_178269253_+_COPA_ENST00000368069_chr1_160310084_-_4065nt ATGTTCCCGGCGCTGGAGTCCGACTCGCCGCTGCCCCCGGAGGACCTGGACGCGGTTGTCCCAGTCAGTGGAGCCGTCGCCGGTGGCATG TTGGATCGGATCCTTCTGGAGTCCGTGTGCCAGCAACAGAGCTGGGTCCGGGTGTACGATGTGAAAGGACCACCCACCCACCGTCTGTCT TGTGGTCAGTCACCCTACACCGAGACAACAACGTGGGAGCGGAAGTATTGCATCCTCACAGACAGCCAGTTGGTATTGCTCAACAAGGAG AAGGAGATACCTGTGGAAGGGGGACAGGAGCAGCAGACAGATTCCACCAAAGGGCGATGCCTGAGGAGAACTGTCAGTGTCCCTTCCGAG GGTCAGTTTCCCGAGTACCCACCAGAGGGCGCCACTAAACTGGGGCTCAGCTTTCACCCCAAAAGACCTTGGATCCTGACTAGTTTACAT AATGGGGTCATCCAGTTATGGGACTATCGGATGTGCACTCTCATTGACAAGTTTGATGAACATGATGGTCCAGTGCGAGGCATTGACTTC CATAAGCAGCAGCCACTGTTCGTCTCTGGAGGAGATGACTATAAGATTAAGGTTTGGAATTACAAGCTTCGGCGCTGTCTTTTCACATTG CTTGGGCACTTAGATTATATTCGCACCACGTTTTTTCATCATGAATATCCCTGGATTCTGAGTGCCTCCGATGATCAGACCATCCGAGTG TGGAACTGGCAATCTAGAACCTGTGTTTGTGTGTTAACAGGGCACAACCATTATGTGATGTGTGCTCAGTTCCACCCCACAGAAGACTTG GTAGTATCAGCCAGCCTGGACCAGACTGTGCGCGTTTGGGATATTTCTGGTCTGAGGAAAAAAAACCTGTCCCCTGGTGCGGTGGAATCG GATGTGAGAGGAATAACTGGGGTTGATCTATTTGGAACTACAGATGCAGTGGTGAAGCATGTACTAGAGGGTCACGATCGTGGAGTAAAC TGGGCTGCCTTCCACCCCACTATGCCCCTTATTGTATCTGGGGCAGATGATCGTCAAGTGAAGATCTGGCGCATGAATGAATCAAAGGCA TGGGAGGTTGATACCTGCCGGGGCCATTACAACAATGTATCTTGTGCCGTCTTCCACCCTCGCCAAGAGTTGATCCTCAGCAATTCTGAG GACAAGAGTATTCGAGTCTGGGATATGTCTAAGCGGACTGGGGTTCAGACTTTCCGCAGAGACCATGATCGTTTCTGGGTCCTAGCTGCT CACCCTAACCTTAACCTCTTTGCAGCAGGCCATGATGGTGGTATGATTGTGTTTAAGCTGGAACGGGAACGGCCAGCCTATGCTGTTCAT GGCAATATGCTACACTATGTCAAGGACCGATTCTTACGACAGCTGGATTTCAACAGCTCCAAAGATGTAGCTGTGATGCAGTTGCGGAGT GGTTCCAAGTTTCCAGTATTCAATATGTCATACAATCCAGCAGAAAATGCAGTCCTGCTTTGTACAAGAGCTAGCAATCTAGAGAATAGT ACCTATGACCTGTACACCATCCCTAAAGATGCTGACTCCCAGAATCCTGATGCGCCTGAAGGGAAACGATCCTCAGGCCTGACAGCCGTT TGGGTCGCTCGAAATCGGTTTGCTGTCCTAGATCGGATGCATTCGCTTCTGATCAAGAATCTGAAGAATGAGATCACCAAAAAGGTACAG GTGCCCAACTGTGATGAGATCTTCTATGCTGGCACAGGCAATCTCCTGCTTCGAGATGCGGACTCTATCACACTCTTTGACGTACAGCAG AAGCGGACTCTGGCATCTGTGAAGATTTCTAAAGTGAAATACGTTATCTGGTCAGCAGACATGTCACATGTAGCACTACTAGCCAAACAC GAACACTCATGCCCTTTGCCTCTTACAGCCATTGTGATCTGTAACCGCAAACTGGATGCTTTATGTAACATTCATGAGAACATTCGTGTC AAGAGTGGGGCCTGGGATGAGAGTGGGGTATTTATCTATACCACAAGCAACCACATCAAATATGCTGTCACCACTGGGGACCACGGGATC ATTCGAACTCTGGATTTACCCATCTATGTCACACGGGTGAAGGGCAACAATGTATACTGCCTAGACAGGGAGTGTCGTCCCCGGGTACTC ACCATTGATCCCACTGAGTTCAAATTCAAGCTGGCCCTGATCAACAGAAAATATGATGAGGTACTGCACATGGTGAGGAATGCCAAACTA GTTGGCCAGTCTATTATTGCTTATCTCCAGAAGAAGGGCTATCCTGAAGTGGCACTGCATTTTGTCAAGGATGAGAAAACTCGCTTTAGT CTGGCACTGGAGTGTGGAAACATTGAGATTGCTCTGGAAGCAGCCAAAGCACTGGATGACAAGAACTGCTGGGAAAAGCTGGGAGAAGTG GCCCTGCTGCAGGGGAACCACCAGATTGTGGAAATGTGCTATCAGCGTACCAAAAACTTTGACAAACTTTCCTTCCTGTATCTTATCACT GGCAACTTAGAAAAACTTCGCAAGATGATGAAGATTGCTGAGATCAGAAAGGACATGAGTGGCCACTATCAGAATGCCCTATACCTGGGT GATGTGTCAGAGCGTGTGCGGATCCTGAAGAACTGTGGACAGAAGTCCCTGGCCTATCTCACAGCTGCTACCCATGGCTTAGATGAAGAA GCTGAGAGCCTAAAGGAGACATTTGACCCAGAGAAGGAGACAATCCCAGACATTGACCCTAATGCCAAGCTGCTCCAGCCACCTGCACCT ATCATGCCATTGGATACCAATTGGCCTTTATTGACTGTATCCAAAGGATTTTTTGAAGGCACCATTGCCAGCAAAGGGAAGGGAGGAGCA CTGGCTGCTGACATTGACATTGACACTGTTGGTACAGAGGGCTGGGGAGAGGATGCAGAGCTGCAGTTGGATGAAGATGGGTTTGTGGAG GCTACAGAAGGTTTGGGGGATGATGCTCTTGGCAAGGGACAGGAAGAAGGAGGTGGCTGGGATGTAGAAGAAGATCTGGAGCTCCCTCCT GAGCTGGATATATCCCCTGGGGCAGCTGGTGGGGCTGAAGATGGTTTCTTTGTGCCCCCAACCAAGGGAACAAGTCCAACTCAGATCTGG TGTAATAACTCTCAGCTTCCAGTTGATCACATCCTGGCAGGCTCTTTCGAAACAGCCATGCGGCTCCTTCATGACCAAGTAGGGGTAATC CAGTTTGGCCCCTACAAGCAACTGTTCCTACAGACATACGCCCGAGGCCGCACAACCTATCAGGCTCTGCCCTGCCTACCCTCCATGTAT GGCTATCCTAATCGCAACTGGAAGGATGCAGGGCTGAAGAATGGTGTACCAGCTGTGGGCCTGAAGCTTAATGACCTCATCCAACGGTTG CAGCTGTGCTACCAGCTCACCACAGTTGGCAAATTTGAGGAGGCTGTGGAAAAATTCCGTTCCATCCTTCTCAGTGTGCCACTTCTTGTT GTGGACAATAAACAAGAGATTGCAGAGGCCCAGCAGCTCATCACCATTTGCCGTGAGTACATTGTGGGTTTGTCCGTGGAGACAGAAAGG AAGAAGCTGCCCAAAGAGACTCTAGAACAGCAGAAGCGCATCTGTGAGATGGCAGCCTATTTCACCCACTCAAACCTGCAGCCTGTGCAC ATGATCCTGGTGCTGCGTACAGCCCTCAATCTGTTCTTCAAGCTCAAGAACTTCAAGACAGCTGCCACCTTTGCTCGGCGCCTACTAGAA CTCGGGCCCAAGCCTGAGGTGGCCCAACAGACCCGAAAAATCCTGTCTGCCTGTGAGAAGAATCCCACAGATGCCTACCAGCTCAATTAT GACATGCACAACCCCTTTGACATTTGTGCTGCATCATATCGGCCCATCTACCGTGGAAAGCCAGTAGAAAAGTGTCCACTCAGTGGGGCC TGCTATTCCCCTGAGTTCAAAGGTCAAATCTGCAGGGTCACCACAGTGACAGAGATTGGCAAAGATGTGATTGGTTTAAGGATCAGTCCT >In-frame_RASAL2_ENST00000448150_chr1_178269253_+_COPA_ENST00000241704_chr1_160310084_-_4038nt ATGTTCCCGGCGCTGGAGTCCGACTCGCCGCTGCCCCCGGAGGACCTGGACGCGGTTGTCCCAGTCAGTGGAGCCGTCGCCGGTGGCATG TTGGATCGGATCCTTCTGGAGTCCGTGTGCCAGCAACAGAGCTGGGTCCGGGTGTACGATGTGAAAGGACCACCCACCCACCGTCTGTCT TGTGGTCAGTCACCCTACACCGAGACAACAACGTGGGAGCGGAAGTATTGCATCCTCACAGACAGCCAGTTGGTATTGCTCAACAAGGAG AAGGAGATACCTGTGGAAGGGGGACAGGAGCAGCAGACAGATTCCACCAAAGGGCGATGCCTGAGGAGAACTGTCAGTGTCCCTTCCGAG GGTCAGTTTCCCGAGTACCCACCAGAGGGCGCCACTAAACTGGGGCTCAGCTTTCACCCCAAAAGACCTTGGATCCTGACTAGTTTACAT AATGGGGTCATCCAGTTATGGGACTATCGGATGTGCACTCTCATTGACAAGTTTGATGAACATGATGGTCCAGTGCGAGGCATTGACTTC CATAAGCAGCAGCCACTGTTCGTCTCTGGAGGAGATGACTATAAGATTAAGGTTTGGAATTACAAGCTTCGGCGCTGTCTTTTCACATTG CTTGGGCACTTAGATTATATTCGCACCACGTTTTTTCATCATGAATATCCCTGGATTCTGAGTGCCTCCGATGATCAGACCATCCGAGTG TGGAACTGGCAATCTAGAACCTGTGTTTGTGTGTTAACAGGGCACAACCATTATGTGATGTGTGCTCAGTTCCACCCCACAGAAGACTTG GTAGTATCAGCCAGCCTGGACCAGACTGTGCGCGTTTGGGATATTTCTGGTCTGAGGAAAAAAAACCTGTCCCCTGGTGCGGTGGAATCG GATGTGAGAGGAATAACTGGGGTTGATCTATTTGGAACTACAGATGCAGTGGTGAAGCATGTACTAGAGGGTCACGATCGTGGAGTAAAC TGGGCTGCCTTCCACCCCACTATGCCCCTTATTGTATCTGGGGCAGATGATCGTCAAGTGAAGATCTGGCGCATGAATGAATCAAAGGCA TGGGAGGTTGATACCTGCCGGGGCCATTACAACAATGTATCTTGTGCCGTCTTCCACCCTCGCCAAGAGTTGATCCTCAGCAATTCTGAG GACAAGAGTATTCGAGTCTGGGATATGTCTAAGCGGACTGGGGTTCAGACTTTCCGCAGAGACCATGATCGTTTCTGGGTCCTAGCTGCT CACCCTAACCTTAACCTCTTTGCAGCAGGCCATGATGGTGGTATGATTGTGTTTAAGCTGGAACGGGAACGGCCAGCCTATGCTGTTCAT GGCAATATGCTACACTATGTCAAGGACCGATTCTTACGACAGCTGGATTTCAACAGCTCCAAAGATGTAGCTGTGATGCAGTTGCGGAGT GGTTCCAAGTTTCCAGTATTCAATATGTCATACAATCCAGCAGAAAATGCAGTCCTGCTTTGTACAAGAGCTAGCAATCTAGAGAATAGT ACCTATGACCTGTACACCATCCCTAAAGATGCTGACTCCCAGAATCCTGATGCGCCTGAAGGGAAACGATCCTCAGGCCTGACAGCCGTT TGGGTCGCTCGAAATCGGTTTGCTGTCCTAGATCGGATGCATTCGCTTCTGATCAAGAATCTGAAGAATGAGATCACCAAAAAGGTACAG GTGCCCAACTGTGATGAGATCTTCTATGCTGGCACAGGCAATCTCCTGCTTCGAGATGCGGACTCTATCACACTCTTTGACGTACAGCAG AAGCGGACTCTGGCATCTGTGAAGATTTCTAAAGTGAAATACGTTATCTGGTCAGCAGACATGTCACATGTAGCACTACTAGCCAAACAC GCCATTGTGATCTGTAACCGCAAACTGGATGCTTTATGTAACATTCATGAGAACATTCGTGTCAAGAGTGGGGCCTGGGATGAGAGTGGG GTATTTATCTATACCACAAGCAACCACATCAAATATGCTGTCACCACTGGGGACCACGGGATCATTCGAACTCTGGATTTACCCATCTAT GTCACACGGGTGAAGGGCAACAATGTATACTGCCTAGACAGGGAGTGTCGTCCCCGGGTACTCACCATTGATCCCACTGAGTTCAAATTC AAGCTGGCCCTGATCAACAGAAAATATGATGAGGTACTGCACATGGTGAGGAATGCCAAACTAGTTGGCCAGTCTATTATTGCTTATCTC CAGAAGAAGGGCTATCCTGAAGTGGCACTGCATTTTGTCAAGGATGAGAAAACTCGCTTTAGTCTGGCACTGGAGTGTGGAAACATTGAG ATTGCTCTGGAAGCAGCCAAAGCACTGGATGACAAGAACTGCTGGGAAAAGCTGGGAGAAGTGGCCCTGCTGCAGGGGAACCACCAGATT GTGGAAATGTGCTATCAGCGTACCAAAAACTTTGACAAACTTTCCTTCCTGTATCTTATCACTGGCAACTTAGAAAAACTTCGCAAGATG ATGAAGATTGCTGAGATCAGAAAGGACATGAGTGGCCACTATCAGAATGCCCTATACCTGGGTGATGTGTCAGAGCGTGTGCGGATCCTG AAGAACTGTGGACAGAAGTCCCTGGCCTATCTCACAGCTGCTACCCATGGCTTAGATGAAGAAGCTGAGAGCCTAAAGGAGACATTTGAC CCAGAGAAGGAGACAATCCCAGACATTGACCCTAATGCCAAGCTGCTCCAGCCACCTGCACCTATCATGCCATTGGATACCAATTGGCCT TTATTGACTGTATCCAAAGGATTTTTTGAAGGCACCATTGCCAGCAAAGGGAAGGGAGGAGCACTGGCTGCTGACATTGACATTGACACT GTTGGTACAGAGGGCTGGGGAGAGGATGCAGAGCTGCAGTTGGATGAAGATGGGTTTGTGGAGGCTACAGAAGGTTTGGGGGATGATGCT CTTGGCAAGGGACAGGAAGAAGGAGGTGGCTGGGATGTAGAAGAAGATCTGGAGCTCCCTCCTGAGCTGGATATATCCCCTGGGGCAGCT GGTGGGGCTGAAGATGGTTTCTTTGTGCCCCCAACCAAGGGAACAAGTCCAACTCAGATCTGGTGTAATAACTCTCAGCTTCCAGTTGAT CACATCCTGGCAGGCTCTTTCGAAACAGCCATGCGGCTCCTTCATGACCAAGTAGGGGTAATCCAGTTTGGCCCCTACAAGCAACTGTTC CTACAGACATACGCCCGAGGCCGCACAACCTATCAGGCTCTGCCCTGCCTACCCTCCATGTATGGCTATCCTAATCGCAACTGGAAGGAT GCAGGGCTGAAGAATGGTGTACCAGCTGTGGGCCTGAAGCTTAATGACCTCATCCAACGGTTGCAGCTGTGCTACCAGCTCACCACAGTT GGCAAATTTGAGGAGGCTGTGGAAAAATTCCGTTCCATCCTTCTCAGTGTGCCACTTCTTGTTGTGGACAATAAACAAGAGATTGCAGAG GCCCAGCAGCTCATCACCATTTGCCGTGAGTACATTGTGGGTTTGTCCGTGGAGACAGAAAGGAAGAAGCTGCCCAAAGAGACTCTAGAA CAGCAGAAGCGCATCTGTGAGATGGCAGCCTATTTCACCCACTCAAACCTGCAGCCTGTGCACATGATCCTGGTGCTGCGTACAGCCCTC AATCTGTTCTTCAAGCTCAAGAACTTCAAGACAGCTGCCACCTTTGCTCGGCGCCTACTAGAACTCGGGCCCAAGCCTGAGGTGGCCCAA CAGACCCGAAAAATCCTGTCTGCCTGTGAGAAGAATCCCACAGATGCCTACCAGCTCAATTATGACATGCACAACCCCTTTGACATTTGT GCTGCATCATATCGGCCCATCTACCGTGGAAAGCCAGTAGAAAAGTGTCCACTCAGTGGGGCCTGCTATTCCCCTGAGTTCAAAGGTCAA >In-frame_RASAL2_ENST00000367649_chr1_178269253_+_COPA_ENST00000368069_chr1_160310084_-_4119nt ATGGAGCTCTCTCCGTCGTCCGGAGGAGCCGCGGAGGCGCTGTCCTGGCCGGAGATGTTCCCGGCGCTGGAGTCCGACTCGCCGCTGCCC CCGGAGGACCTGGACGCGGTTGTCCCAGTCAGTGGAGCCGTCGCCGGTGGCATGTTGGATCGGATCCTTCTGGAGTCCGTGTGCCAGCAA CAGAGCTGGGTCCGGGTGTACGATGTGAAAGGACCACCCACCCACCGTCTGTCTTGTGGTCAGTCACCCTACACCGAGACAACAACGTGG GAGCGGAAGTATTGCATCCTCACAGACAGCCAGTTGGTATTGCTCAACAAGGAGAAGGAGATACCTGTGGAAGGGGGACAGGAGCAGCAG ACAGATTCCACCAAAGGGCGATGCCTGAGGAGAACTGTCAGTGTCCCTTCCGAGGGTCAGTTTCCCGAGTACCCACCAGAGGGCGCCACT AAACTGGGGCTCAGCTTTCACCCCAAAAGACCTTGGATCCTGACTAGTTTACATAATGGGGTCATCCAGTTATGGGACTATCGGATGTGC ACTCTCATTGACAAGTTTGATGAACATGATGGTCCAGTGCGAGGCATTGACTTCCATAAGCAGCAGCCACTGTTCGTCTCTGGAGGAGAT GACTATAAGATTAAGGTTTGGAATTACAAGCTTCGGCGCTGTCTTTTCACATTGCTTGGGCACTTAGATTATATTCGCACCACGTTTTTT CATCATGAATATCCCTGGATTCTGAGTGCCTCCGATGATCAGACCATCCGAGTGTGGAACTGGCAATCTAGAACCTGTGTTTGTGTGTTA ACAGGGCACAACCATTATGTGATGTGTGCTCAGTTCCACCCCACAGAAGACTTGGTAGTATCAGCCAGCCTGGACCAGACTGTGCGCGTT TGGGATATTTCTGGTCTGAGGAAAAAAAACCTGTCCCCTGGTGCGGTGGAATCGGATGTGAGAGGAATAACTGGGGTTGATCTATTTGGA ACTACAGATGCAGTGGTGAAGCATGTACTAGAGGGTCACGATCGTGGAGTAAACTGGGCTGCCTTCCACCCCACTATGCCCCTTATTGTA TCTGGGGCAGATGATCGTCAAGTGAAGATCTGGCGCATGAATGAATCAAAGGCATGGGAGGTTGATACCTGCCGGGGCCATTACAACAAT GTATCTTGTGCCGTCTTCCACCCTCGCCAAGAGTTGATCCTCAGCAATTCTGAGGACAAGAGTATTCGAGTCTGGGATATGTCTAAGCGG ACTGGGGTTCAGACTTTCCGCAGAGACCATGATCGTTTCTGGGTCCTAGCTGCTCACCCTAACCTTAACCTCTTTGCAGCAGGCCATGAT GGTGGTATGATTGTGTTTAAGCTGGAACGGGAACGGCCAGCCTATGCTGTTCATGGCAATATGCTACACTATGTCAAGGACCGATTCTTA CGACAGCTGGATTTCAACAGCTCCAAAGATGTAGCTGTGATGCAGTTGCGGAGTGGTTCCAAGTTTCCAGTATTCAATATGTCATACAAT CCAGCAGAAAATGCAGTCCTGCTTTGTACAAGAGCTAGCAATCTAGAGAATAGTACCTATGACCTGTACACCATCCCTAAAGATGCTGAC TCCCAGAATCCTGATGCGCCTGAAGGGAAACGATCCTCAGGCCTGACAGCCGTTTGGGTCGCTCGAAATCGGTTTGCTGTCCTAGATCGG ATGCATTCGCTTCTGATCAAGAATCTGAAGAATGAGATCACCAAAAAGGTACAGGTGCCCAACTGTGATGAGATCTTCTATGCTGGCACA GGCAATCTCCTGCTTCGAGATGCGGACTCTATCACACTCTTTGACGTACAGCAGAAGCGGACTCTGGCATCTGTGAAGATTTCTAAAGTG AAATACGTTATCTGGTCAGCAGACATGTCACATGTAGCACTACTAGCCAAACACGAACACTCATGCCCTTTGCCTCTTACAGCCATTGTG ATCTGTAACCGCAAACTGGATGCTTTATGTAACATTCATGAGAACATTCGTGTCAAGAGTGGGGCCTGGGATGAGAGTGGGGTATTTATC TATACCACAAGCAACCACATCAAATATGCTGTCACCACTGGGGACCACGGGATCATTCGAACTCTGGATTTACCCATCTATGTCACACGG GTGAAGGGCAACAATGTATACTGCCTAGACAGGGAGTGTCGTCCCCGGGTACTCACCATTGATCCCACTGAGTTCAAATTCAAGCTGGCC CTGATCAACAGAAAATATGATGAGGTACTGCACATGGTGAGGAATGCCAAACTAGTTGGCCAGTCTATTATTGCTTATCTCCAGAAGAAG GGCTATCCTGAAGTGGCACTGCATTTTGTCAAGGATGAGAAAACTCGCTTTAGTCTGGCACTGGAGTGTGGAAACATTGAGATTGCTCTG GAAGCAGCCAAAGCACTGGATGACAAGAACTGCTGGGAAAAGCTGGGAGAAGTGGCCCTGCTGCAGGGGAACCACCAGATTGTGGAAATG TGCTATCAGCGTACCAAAAACTTTGACAAACTTTCCTTCCTGTATCTTATCACTGGCAACTTAGAAAAACTTCGCAAGATGATGAAGATT GCTGAGATCAGAAAGGACATGAGTGGCCACTATCAGAATGCCCTATACCTGGGTGATGTGTCAGAGCGTGTGCGGATCCTGAAGAACTGT GGACAGAAGTCCCTGGCCTATCTCACAGCTGCTACCCATGGCTTAGATGAAGAAGCTGAGAGCCTAAAGGAGACATTTGACCCAGAGAAG GAGACAATCCCAGACATTGACCCTAATGCCAAGCTGCTCCAGCCACCTGCACCTATCATGCCATTGGATACCAATTGGCCTTTATTGACT GTATCCAAAGGATTTTTTGAAGGCACCATTGCCAGCAAAGGGAAGGGAGGAGCACTGGCTGCTGACATTGACATTGACACTGTTGGTACA GAGGGCTGGGGAGAGGATGCAGAGCTGCAGTTGGATGAAGATGGGTTTGTGGAGGCTACAGAAGGTTTGGGGGATGATGCTCTTGGCAAG GGACAGGAAGAAGGAGGTGGCTGGGATGTAGAAGAAGATCTGGAGCTCCCTCCTGAGCTGGATATATCCCCTGGGGCAGCTGGTGGGGCT GAAGATGGTTTCTTTGTGCCCCCAACCAAGGGAACAAGTCCAACTCAGATCTGGTGTAATAACTCTCAGCTTCCAGTTGATCACATCCTG GCAGGCTCTTTCGAAACAGCCATGCGGCTCCTTCATGACCAAGTAGGGGTAATCCAGTTTGGCCCCTACAAGCAACTGTTCCTACAGACA TACGCCCGAGGCCGCACAACCTATCAGGCTCTGCCCTGCCTACCCTCCATGTATGGCTATCCTAATCGCAACTGGAAGGATGCAGGGCTG AAGAATGGTGTACCAGCTGTGGGCCTGAAGCTTAATGACCTCATCCAACGGTTGCAGCTGTGCTACCAGCTCACCACAGTTGGCAAATTT GAGGAGGCTGTGGAAAAATTCCGTTCCATCCTTCTCAGTGTGCCACTTCTTGTTGTGGACAATAAACAAGAGATTGCAGAGGCCCAGCAG CTCATCACCATTTGCCGTGAGTACATTGTGGGTTTGTCCGTGGAGACAGAAAGGAAGAAGCTGCCCAAAGAGACTCTAGAACAGCAGAAG CGCATCTGTGAGATGGCAGCCTATTTCACCCACTCAAACCTGCAGCCTGTGCACATGATCCTGGTGCTGCGTACAGCCCTCAATCTGTTC TTCAAGCTCAAGAACTTCAAGACAGCTGCCACCTTTGCTCGGCGCCTACTAGAACTCGGGCCCAAGCCTGAGGTGGCCCAACAGACCCGA AAAATCCTGTCTGCCTGTGAGAAGAATCCCACAGATGCCTACCAGCTCAATTATGACATGCACAACCCCTTTGACATTTGTGCTGCATCA TATCGGCCCATCTACCGTGGAAAGCCAGTAGAAAAGTGTCCACTCAGTGGGGCCTGCTATTCCCCTGAGTTCAAAGGTCAAATCTGCAGG >In-frame_RASAL2_ENST00000367649_chr1_178269253_+_COPA_ENST00000241704_chr1_160310084_-_4092nt ATGGAGCTCTCTCCGTCGTCCGGAGGAGCCGCGGAGGCGCTGTCCTGGCCGGAGATGTTCCCGGCGCTGGAGTCCGACTCGCCGCTGCCC CCGGAGGACCTGGACGCGGTTGTCCCAGTCAGTGGAGCCGTCGCCGGTGGCATGTTGGATCGGATCCTTCTGGAGTCCGTGTGCCAGCAA CAGAGCTGGGTCCGGGTGTACGATGTGAAAGGACCACCCACCCACCGTCTGTCTTGTGGTCAGTCACCCTACACCGAGACAACAACGTGG GAGCGGAAGTATTGCATCCTCACAGACAGCCAGTTGGTATTGCTCAACAAGGAGAAGGAGATACCTGTGGAAGGGGGACAGGAGCAGCAG ACAGATTCCACCAAAGGGCGATGCCTGAGGAGAACTGTCAGTGTCCCTTCCGAGGGTCAGTTTCCCGAGTACCCACCAGAGGGCGCCACT AAACTGGGGCTCAGCTTTCACCCCAAAAGACCTTGGATCCTGACTAGTTTACATAATGGGGTCATCCAGTTATGGGACTATCGGATGTGC ACTCTCATTGACAAGTTTGATGAACATGATGGTCCAGTGCGAGGCATTGACTTCCATAAGCAGCAGCCACTGTTCGTCTCTGGAGGAGAT GACTATAAGATTAAGGTTTGGAATTACAAGCTTCGGCGCTGTCTTTTCACATTGCTTGGGCACTTAGATTATATTCGCACCACGTTTTTT CATCATGAATATCCCTGGATTCTGAGTGCCTCCGATGATCAGACCATCCGAGTGTGGAACTGGCAATCTAGAACCTGTGTTTGTGTGTTA ACAGGGCACAACCATTATGTGATGTGTGCTCAGTTCCACCCCACAGAAGACTTGGTAGTATCAGCCAGCCTGGACCAGACTGTGCGCGTT TGGGATATTTCTGGTCTGAGGAAAAAAAACCTGTCCCCTGGTGCGGTGGAATCGGATGTGAGAGGAATAACTGGGGTTGATCTATTTGGA ACTACAGATGCAGTGGTGAAGCATGTACTAGAGGGTCACGATCGTGGAGTAAACTGGGCTGCCTTCCACCCCACTATGCCCCTTATTGTA TCTGGGGCAGATGATCGTCAAGTGAAGATCTGGCGCATGAATGAATCAAAGGCATGGGAGGTTGATACCTGCCGGGGCCATTACAACAAT GTATCTTGTGCCGTCTTCCACCCTCGCCAAGAGTTGATCCTCAGCAATTCTGAGGACAAGAGTATTCGAGTCTGGGATATGTCTAAGCGG ACTGGGGTTCAGACTTTCCGCAGAGACCATGATCGTTTCTGGGTCCTAGCTGCTCACCCTAACCTTAACCTCTTTGCAGCAGGCCATGAT GGTGGTATGATTGTGTTTAAGCTGGAACGGGAACGGCCAGCCTATGCTGTTCATGGCAATATGCTACACTATGTCAAGGACCGATTCTTA CGACAGCTGGATTTCAACAGCTCCAAAGATGTAGCTGTGATGCAGTTGCGGAGTGGTTCCAAGTTTCCAGTATTCAATATGTCATACAAT CCAGCAGAAAATGCAGTCCTGCTTTGTACAAGAGCTAGCAATCTAGAGAATAGTACCTATGACCTGTACACCATCCCTAAAGATGCTGAC TCCCAGAATCCTGATGCGCCTGAAGGGAAACGATCCTCAGGCCTGACAGCCGTTTGGGTCGCTCGAAATCGGTTTGCTGTCCTAGATCGG ATGCATTCGCTTCTGATCAAGAATCTGAAGAATGAGATCACCAAAAAGGTACAGGTGCCCAACTGTGATGAGATCTTCTATGCTGGCACA GGCAATCTCCTGCTTCGAGATGCGGACTCTATCACACTCTTTGACGTACAGCAGAAGCGGACTCTGGCATCTGTGAAGATTTCTAAAGTG AAATACGTTATCTGGTCAGCAGACATGTCACATGTAGCACTACTAGCCAAACACGCCATTGTGATCTGTAACCGCAAACTGGATGCTTTA TGTAACATTCATGAGAACATTCGTGTCAAGAGTGGGGCCTGGGATGAGAGTGGGGTATTTATCTATACCACAAGCAACCACATCAAATAT GCTGTCACCACTGGGGACCACGGGATCATTCGAACTCTGGATTTACCCATCTATGTCACACGGGTGAAGGGCAACAATGTATACTGCCTA GACAGGGAGTGTCGTCCCCGGGTACTCACCATTGATCCCACTGAGTTCAAATTCAAGCTGGCCCTGATCAACAGAAAATATGATGAGGTA CTGCACATGGTGAGGAATGCCAAACTAGTTGGCCAGTCTATTATTGCTTATCTCCAGAAGAAGGGCTATCCTGAAGTGGCACTGCATTTT GTCAAGGATGAGAAAACTCGCTTTAGTCTGGCACTGGAGTGTGGAAACATTGAGATTGCTCTGGAAGCAGCCAAAGCACTGGATGACAAG AACTGCTGGGAAAAGCTGGGAGAAGTGGCCCTGCTGCAGGGGAACCACCAGATTGTGGAAATGTGCTATCAGCGTACCAAAAACTTTGAC AAACTTTCCTTCCTGTATCTTATCACTGGCAACTTAGAAAAACTTCGCAAGATGATGAAGATTGCTGAGATCAGAAAGGACATGAGTGGC CACTATCAGAATGCCCTATACCTGGGTGATGTGTCAGAGCGTGTGCGGATCCTGAAGAACTGTGGACAGAAGTCCCTGGCCTATCTCACA GCTGCTACCCATGGCTTAGATGAAGAAGCTGAGAGCCTAAAGGAGACATTTGACCCAGAGAAGGAGACAATCCCAGACATTGACCCTAAT GCCAAGCTGCTCCAGCCACCTGCACCTATCATGCCATTGGATACCAATTGGCCTTTATTGACTGTATCCAAAGGATTTTTTGAAGGCACC ATTGCCAGCAAAGGGAAGGGAGGAGCACTGGCTGCTGACATTGACATTGACACTGTTGGTACAGAGGGCTGGGGAGAGGATGCAGAGCTG CAGTTGGATGAAGATGGGTTTGTGGAGGCTACAGAAGGTTTGGGGGATGATGCTCTTGGCAAGGGACAGGAAGAAGGAGGTGGCTGGGAT GTAGAAGAAGATCTGGAGCTCCCTCCTGAGCTGGATATATCCCCTGGGGCAGCTGGTGGGGCTGAAGATGGTTTCTTTGTGCCCCCAACC AAGGGAACAAGTCCAACTCAGATCTGGTGTAATAACTCTCAGCTTCCAGTTGATCACATCCTGGCAGGCTCTTTCGAAACAGCCATGCGG CTCCTTCATGACCAAGTAGGGGTAATCCAGTTTGGCCCCTACAAGCAACTGTTCCTACAGACATACGCCCGAGGCCGCACAACCTATCAG GCTCTGCCCTGCCTACCCTCCATGTATGGCTATCCTAATCGCAACTGGAAGGATGCAGGGCTGAAGAATGGTGTACCAGCTGTGGGCCTG AAGCTTAATGACCTCATCCAACGGTTGCAGCTGTGCTACCAGCTCACCACAGTTGGCAAATTTGAGGAGGCTGTGGAAAAATTCCGTTCC ATCCTTCTCAGTGTGCCACTTCTTGTTGTGGACAATAAACAAGAGATTGCAGAGGCCCAGCAGCTCATCACCATTTGCCGTGAGTACATT GTGGGTTTGTCCGTGGAGACAGAAAGGAAGAAGCTGCCCAAAGAGACTCTAGAACAGCAGAAGCGCATCTGTGAGATGGCAGCCTATTTC ACCCACTCAAACCTGCAGCCTGTGCACATGATCCTGGTGCTGCGTACAGCCCTCAATCTGTTCTTCAAGCTCAAGAACTTCAAGACAGCT GCCACCTTTGCTCGGCGCCTACTAGAACTCGGGCCCAAGCCTGAGGTGGCCCAACAGACCCGAAAAATCCTGTCTGCCTGTGAGAAGAAT CCCACAGATGCCTACCAGCTCAATTATGACATGCACAACCCCTTTGACATTTGTGCTGCATCATATCGGCCCATCTACCGTGGAAAGCCA GTAGAAAAGTGTCCACTCAGTGGGGCCTGCTATTCCCCTGAGTTCAAAGGTCAAATCTGCAGGGTCACCACAGTGACAGAGATTGGCAAA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_RASAL2_ENST00000448150_chr1_178269253_+_COPA_ENST00000368069_chr1_160310084_-_5767nt CCCTCGATTGCTTCAGCCTATCACCCTGGGATGCCGCCTGCCGCTGCCGCCGCCGCCGCCGCCGCCACCGCCACCGCCACCGCCACCGCC ACCGCCGTGGCTGCCGGGTTTGTGGGATCCGCCGCGGAGCAGGAGCCAGAGCTGTGGCCGGAGCTGTGGCCTGAGAGTCAGGGGGCGGGC AGGCTCATTCCAGAAGTGGGGGCCGAGGACAGGCGGGCTAGAACCCGGGGCCACCGCCCCCTACCCCTCCTCAGGCTGAGGGAACGGGCA CTCGGAGCTTCTGAGGCGGCGGCGGCGGGAGCCGGTCAGAGGGGGCGGCCCCTGGCGGCGACGCCCCCAAGCCCAGCCCTGCCCGGCCCC GCTCCATCCCCAGCCAGAGCCTGGTCTGACCGCGAGAGACGCCGGCGGGGCTGAAGAAGGCGGCTCCGAGGAGGTGGGAGGGCGAGCCTC CCCTCCCGGGTTCTTCTGCGTCCTCTCCCGGGAGGGACCCACACACACCTGAGCCCGGACCCACCCTTGGTCGGGGCCACGCTGGATCCT CCTCCCGGCCTGGGTCCCGCCCGCCGACTGCAGGTGGGCTGCATCGCCCGAGCCTCGGGCAGTGGGCGACGGGGAAGGAGGTGAGAGGTG TCCGCGCCGGCTGCCGCTCGGGTCCCTGCCCTCGCTGCGCGCTCTCCTCCTCCCCTTACCGCAGGCAGGGCGCGGAGCCGCGCGCCAGCC CGCCCCGAAGCCGCCGCCTCGTCCCCCTCCCGCCTCGGGGCACCATGGAGCTCTCTCCGTCGTCCGGAGGAGCCGCGGAGGCGCTGTCCT GGCCGGAGATGTTCCCGGCGCTGGAGTCCGACTCGCCGCTGCCCCCGGAGGACCTGGACGCGGTTGTCCCAGTCAGTGGAGCCGTCGCCG GTGGCATGTTGGATCGGATCCTTCTGGAGTCCGTGTGCCAGCAACAGAGCTGGGTCCGGGTGTACGATGTGAAAGGACCACCCACCCACC GTCTGTCTTGTGGTCAGTCACCCTACACCGAGACAACAACGTGGGAGCGGAAGTATTGCATCCTCACAGACAGCCAGTTGGTATTGCTCA ACAAGGAGAAGGAGATACCTGTGGAAGGGGGACAGGAGCAGCAGACAGATTCCACCAAAGGGCGATGCCTGAGGAGAACTGTCAGTGTCC CTTCCGAGGGTCAGTTTCCCGAGTACCCACCAGAGGGCGCCACTAAACTGGGGCTCAGCTTTCACCCCAAAAGACCTTGGATCCTGACTA GTTTACATAATGGGGTCATCCAGTTATGGGACTATCGGATGTGCACTCTCATTGACAAGTTTGATGAACATGATGGTCCAGTGCGAGGCA TTGACTTCCATAAGCAGCAGCCACTGTTCGTCTCTGGAGGAGATGACTATAAGATTAAGGTTTGGAATTACAAGCTTCGGCGCTGTCTTT TCACATTGCTTGGGCACTTAGATTATATTCGCACCACGTTTTTTCATCATGAATATCCCTGGATTCTGAGTGCCTCCGATGATCAGACCA TCCGAGTGTGGAACTGGCAATCTAGAACCTGTGTTTGTGTGTTAACAGGGCACAACCATTATGTGATGTGTGCTCAGTTCCACCCCACAG AAGACTTGGTAGTATCAGCCAGCCTGGACCAGACTGTGCGCGTTTGGGATATTTCTGGTCTGAGGAAAAAAAACCTGTCCCCTGGTGCGG TGGAATCGGATGTGAGAGGAATAACTGGGGTTGATCTATTTGGAACTACAGATGCAGTGGTGAAGCATGTACTAGAGGGTCACGATCGTG GAGTAAACTGGGCTGCCTTCCACCCCACTATGCCCCTTATTGTATCTGGGGCAGATGATCGTCAAGTGAAGATCTGGCGCATGAATGAAT CAAAGGCATGGGAGGTTGATACCTGCCGGGGCCATTACAACAATGTATCTTGTGCCGTCTTCCACCCTCGCCAAGAGTTGATCCTCAGCA ATTCTGAGGACAAGAGTATTCGAGTCTGGGATATGTCTAAGCGGACTGGGGTTCAGACTTTCCGCAGAGACCATGATCGTTTCTGGGTCC TAGCTGCTCACCCTAACCTTAACCTCTTTGCAGCAGGCCATGATGGTGGTATGATTGTGTTTAAGCTGGAACGGGAACGGCCAGCCTATG CTGTTCATGGCAATATGCTACACTATGTCAAGGACCGATTCTTACGACAGCTGGATTTCAACAGCTCCAAAGATGTAGCTGTGATGCAGT TGCGGAGTGGTTCCAAGTTTCCAGTATTCAATATGTCATACAATCCAGCAGAAAATGCAGTCCTGCTTTGTACAAGAGCTAGCAATCTAG AGAATAGTACCTATGACCTGTACACCATCCCTAAAGATGCTGACTCCCAGAATCCTGATGCGCCTGAAGGGAAACGATCCTCAGGCCTGA CAGCCGTTTGGGTCGCTCGAAATCGGTTTGCTGTCCTAGATCGGATGCATTCGCTTCTGATCAAGAATCTGAAGAATGAGATCACCAAAA AGGTACAGGTGCCCAACTGTGATGAGATCTTCTATGCTGGCACAGGCAATCTCCTGCTTCGAGATGCGGACTCTATCACACTCTTTGACG TACAGCAGAAGCGGACTCTGGCATCTGTGAAGATTTCTAAAGTGAAATACGTTATCTGGTCAGCAGACATGTCACATGTAGCACTACTAG CCAAACACGAACACTCATGCCCTTTGCCTCTTACAGCCATTGTGATCTGTAACCGCAAACTGGATGCTTTATGTAACATTCATGAGAACA TTCGTGTCAAGAGTGGGGCCTGGGATGAGAGTGGGGTATTTATCTATACCACAAGCAACCACATCAAATATGCTGTCACCACTGGGGACC ACGGGATCATTCGAACTCTGGATTTACCCATCTATGTCACACGGGTGAAGGGCAACAATGTATACTGCCTAGACAGGGAGTGTCGTCCCC GGGTACTCACCATTGATCCCACTGAGTTCAAATTCAAGCTGGCCCTGATCAACAGAAAATATGATGAGGTACTGCACATGGTGAGGAATG CCAAACTAGTTGGCCAGTCTATTATTGCTTATCTCCAGAAGAAGGGCTATCCTGAAGTGGCACTGCATTTTGTCAAGGATGAGAAAACTC GCTTTAGTCTGGCACTGGAGTGTGGAAACATTGAGATTGCTCTGGAAGCAGCCAAAGCACTGGATGACAAGAACTGCTGGGAAAAGCTGG GAGAAGTGGCCCTGCTGCAGGGGAACCACCAGATTGTGGAAATGTGCTATCAGCGTACCAAAAACTTTGACAAACTTTCCTTCCTGTATC TTATCACTGGCAACTTAGAAAAACTTCGCAAGATGATGAAGATTGCTGAGATCAGAAAGGACATGAGTGGCCACTATCAGAATGCCCTAT ACCTGGGTGATGTGTCAGAGCGTGTGCGGATCCTGAAGAACTGTGGACAGAAGTCCCTGGCCTATCTCACAGCTGCTACCCATGGCTTAG ATGAAGAAGCTGAGAGCCTAAAGGAGACATTTGACCCAGAGAAGGAGACAATCCCAGACATTGACCCTAATGCCAAGCTGCTCCAGCCAC CTGCACCTATCATGCCATTGGATACCAATTGGCCTTTATTGACTGTATCCAAAGGATTTTTTGAAGGCACCATTGCCAGCAAAGGGAAGG GAGGAGCACTGGCTGCTGACATTGACATTGACACTGTTGGTACAGAGGGCTGGGGAGAGGATGCAGAGCTGCAGTTGGATGAAGATGGGT TTGTGGAGGCTACAGAAGGTTTGGGGGATGATGCTCTTGGCAAGGGACAGGAAGAAGGAGGTGGCTGGGATGTAGAAGAAGATCTGGAGC TCCCTCCTGAGCTGGATATATCCCCTGGGGCAGCTGGTGGGGCTGAAGATGGTTTCTTTGTGCCCCCAACCAAGGGAACAAGTCCAACTC AGATCTGGTGTAATAACTCTCAGCTTCCAGTTGATCACATCCTGGCAGGCTCTTTCGAAACAGCCATGCGGCTCCTTCATGACCAAGTAG GGGTAATCCAGTTTGGCCCCTACAAGCAACTGTTCCTACAGACATACGCCCGAGGCCGCACAACCTATCAGGCTCTGCCCTGCCTACCCT CCATGTATGGCTATCCTAATCGCAACTGGAAGGATGCAGGGCTGAAGAATGGTGTACCAGCTGTGGGCCTGAAGCTTAATGACCTCATCC AACGGTTGCAGCTGTGCTACCAGCTCACCACAGTTGGCAAATTTGAGGAGGCTGTGGAAAAATTCCGTTCCATCCTTCTCAGTGTGCCAC TTCTTGTTGTGGACAATAAACAAGAGATTGCAGAGGCCCAGCAGCTCATCACCATTTGCCGTGAGTACATTGTGGGTTTGTCCGTGGAGA CAGAAAGGAAGAAGCTGCCCAAAGAGACTCTAGAACAGCAGAAGCGCATCTGTGAGATGGCAGCCTATTTCACCCACTCAAACCTGCAGC CTGTGCACATGATCCTGGTGCTGCGTACAGCCCTCAATCTGTTCTTCAAGCTCAAGAACTTCAAGACAGCTGCCACCTTTGCTCGGCGCC TACTAGAACTCGGGCCCAAGCCTGAGGTGGCCCAACAGACCCGAAAAATCCTGTCTGCCTGTGAGAAGAATCCCACAGATGCCTACCAGC TCAATTATGACATGCACAACCCCTTTGACATTTGTGCTGCATCATATCGGCCCATCTACCGTGGAAAGCCAGTAGAAAAGTGTCCACTCA GTGGGGCCTGCTATTCCCCTGAGTTCAAAGGTCAAATCTGCAGGGTCACCACAGTGACAGAGATTGGCAAAGATGTGATTGGTTTAAGGA TCAGTCCTCTGCAGTTTCGCTAAGGCCCCCTTTGTGTGCATGGGTCAGTCACCATATGTTCCCCCCAGAGAATGTGTCTATATCCTCCTT CTAACAGCACCTTCCCCCTGCAGCTACTCTTCAGATCTGGCTCTCTGTACCCTAAAACCTAGTATCTTTTTCTCTTCTATGGAAAATCCG AAGGTCTAAACTTGACTTTTTTGAGGTCTTCTCAACTTGACTACAGTTGTGCTCATAATTGTCCTTGCCTTTCCAGCTTAATTATTTTAA GGAACAAATGAAAACTCTGGGCTGGGTGGAGTGGCTCATACCTGTAATCCCAGCACTTTGGGAGGCTACGGTGGGCAGATCATCTGAGGC CAGGAGTTCGAGACCTGCCTGGCCAACATGGCAACACCCCGTCTCTAATAAAAATATAAAAATTAGCCTGGCATGGTAGCATGCGCCTAT AGTCCCAGCTGCTCAGGAGGCTGAGGCATGAGAATCGCTTGAACCTAGGAGGTGGAGGTTGCATTCAACTGAGATCATACCACTTCATTC CAGCCTGGGTGACAGAGCAAGACTCTGTCTCAAAAAAAAAAAAAAGGAAAACTCTGTGATGGACATTTGTTTAGTAAATCCCTTCAGTAT TTATCCCTCCTTTCCCCACAGCAGCTTTCTTTCCTGTCAACTAGAAAGGAGCAGGATGTAATAAATACATTTTGGTGTGACTAGGCCACA CCAACTCTTAATCATCTCCCATTTTCCTTAGACATTTAAATTTCAAGGCAGGTACCCTCTGTGTACTCAGAAATTTGAAGAAGTTATTTG GTTTTCCAAAATGCACACTGCGGGTTATTGATTTGTTCTTTACAACTATTGTTCTCATATTTCTCACACTAAATAAATCTCTATGAGAGC >In-frame_RASAL2_ENST00000448150_chr1_178269253_+_COPA_ENST00000241704_chr1_160310084_-_5740nt CCCTCGATTGCTTCAGCCTATCACCCTGGGATGCCGCCTGCCGCTGCCGCCGCCGCCGCCGCCGCCACCGCCACCGCCACCGCCACCGCC ACCGCCGTGGCTGCCGGGTTTGTGGGATCCGCCGCGGAGCAGGAGCCAGAGCTGTGGCCGGAGCTGTGGCCTGAGAGTCAGGGGGCGGGC AGGCTCATTCCAGAAGTGGGGGCCGAGGACAGGCGGGCTAGAACCCGGGGCCACCGCCCCCTACCCCTCCTCAGGCTGAGGGAACGGGCA CTCGGAGCTTCTGAGGCGGCGGCGGCGGGAGCCGGTCAGAGGGGGCGGCCCCTGGCGGCGACGCCCCCAAGCCCAGCCCTGCCCGGCCCC GCTCCATCCCCAGCCAGAGCCTGGTCTGACCGCGAGAGACGCCGGCGGGGCTGAAGAAGGCGGCTCCGAGGAGGTGGGAGGGCGAGCCTC CCCTCCCGGGTTCTTCTGCGTCCTCTCCCGGGAGGGACCCACACACACCTGAGCCCGGACCCACCCTTGGTCGGGGCCACGCTGGATCCT CCTCCCGGCCTGGGTCCCGCCCGCCGACTGCAGGTGGGCTGCATCGCCCGAGCCTCGGGCAGTGGGCGACGGGGAAGGAGGTGAGAGGTG TCCGCGCCGGCTGCCGCTCGGGTCCCTGCCCTCGCTGCGCGCTCTCCTCCTCCCCTTACCGCAGGCAGGGCGCGGAGCCGCGCGCCAGCC CGCCCCGAAGCCGCCGCCTCGTCCCCCTCCCGCCTCGGGGCACCATGGAGCTCTCTCCGTCGTCCGGAGGAGCCGCGGAGGCGCTGTCCT GGCCGGAGATGTTCCCGGCGCTGGAGTCCGACTCGCCGCTGCCCCCGGAGGACCTGGACGCGGTTGTCCCAGTCAGTGGAGCCGTCGCCG GTGGCATGTTGGATCGGATCCTTCTGGAGTCCGTGTGCCAGCAACAGAGCTGGGTCCGGGTGTACGATGTGAAAGGACCACCCACCCACC GTCTGTCTTGTGGTCAGTCACCCTACACCGAGACAACAACGTGGGAGCGGAAGTATTGCATCCTCACAGACAGCCAGTTGGTATTGCTCA ACAAGGAGAAGGAGATACCTGTGGAAGGGGGACAGGAGCAGCAGACAGATTCCACCAAAGGGCGATGCCTGAGGAGAACTGTCAGTGTCC CTTCCGAGGGTCAGTTTCCCGAGTACCCACCAGAGGGCGCCACTAAACTGGGGCTCAGCTTTCACCCCAAAAGACCTTGGATCCTGACTA GTTTACATAATGGGGTCATCCAGTTATGGGACTATCGGATGTGCACTCTCATTGACAAGTTTGATGAACATGATGGTCCAGTGCGAGGCA TTGACTTCCATAAGCAGCAGCCACTGTTCGTCTCTGGAGGAGATGACTATAAGATTAAGGTTTGGAATTACAAGCTTCGGCGCTGTCTTT TCACATTGCTTGGGCACTTAGATTATATTCGCACCACGTTTTTTCATCATGAATATCCCTGGATTCTGAGTGCCTCCGATGATCAGACCA TCCGAGTGTGGAACTGGCAATCTAGAACCTGTGTTTGTGTGTTAACAGGGCACAACCATTATGTGATGTGTGCTCAGTTCCACCCCACAG AAGACTTGGTAGTATCAGCCAGCCTGGACCAGACTGTGCGCGTTTGGGATATTTCTGGTCTGAGGAAAAAAAACCTGTCCCCTGGTGCGG TGGAATCGGATGTGAGAGGAATAACTGGGGTTGATCTATTTGGAACTACAGATGCAGTGGTGAAGCATGTACTAGAGGGTCACGATCGTG GAGTAAACTGGGCTGCCTTCCACCCCACTATGCCCCTTATTGTATCTGGGGCAGATGATCGTCAAGTGAAGATCTGGCGCATGAATGAAT CAAAGGCATGGGAGGTTGATACCTGCCGGGGCCATTACAACAATGTATCTTGTGCCGTCTTCCACCCTCGCCAAGAGTTGATCCTCAGCA ATTCTGAGGACAAGAGTATTCGAGTCTGGGATATGTCTAAGCGGACTGGGGTTCAGACTTTCCGCAGAGACCATGATCGTTTCTGGGTCC TAGCTGCTCACCCTAACCTTAACCTCTTTGCAGCAGGCCATGATGGTGGTATGATTGTGTTTAAGCTGGAACGGGAACGGCCAGCCTATG CTGTTCATGGCAATATGCTACACTATGTCAAGGACCGATTCTTACGACAGCTGGATTTCAACAGCTCCAAAGATGTAGCTGTGATGCAGT TGCGGAGTGGTTCCAAGTTTCCAGTATTCAATATGTCATACAATCCAGCAGAAAATGCAGTCCTGCTTTGTACAAGAGCTAGCAATCTAG AGAATAGTACCTATGACCTGTACACCATCCCTAAAGATGCTGACTCCCAGAATCCTGATGCGCCTGAAGGGAAACGATCCTCAGGCCTGA CAGCCGTTTGGGTCGCTCGAAATCGGTTTGCTGTCCTAGATCGGATGCATTCGCTTCTGATCAAGAATCTGAAGAATGAGATCACCAAAA AGGTACAGGTGCCCAACTGTGATGAGATCTTCTATGCTGGCACAGGCAATCTCCTGCTTCGAGATGCGGACTCTATCACACTCTTTGACG TACAGCAGAAGCGGACTCTGGCATCTGTGAAGATTTCTAAAGTGAAATACGTTATCTGGTCAGCAGACATGTCACATGTAGCACTACTAG CCAAACACGCCATTGTGATCTGTAACCGCAAACTGGATGCTTTATGTAACATTCATGAGAACATTCGTGTCAAGAGTGGGGCCTGGGATG AGAGTGGGGTATTTATCTATACCACAAGCAACCACATCAAATATGCTGTCACCACTGGGGACCACGGGATCATTCGAACTCTGGATTTAC CCATCTATGTCACACGGGTGAAGGGCAACAATGTATACTGCCTAGACAGGGAGTGTCGTCCCCGGGTACTCACCATTGATCCCACTGAGT TCAAATTCAAGCTGGCCCTGATCAACAGAAAATATGATGAGGTACTGCACATGGTGAGGAATGCCAAACTAGTTGGCCAGTCTATTATTG CTTATCTCCAGAAGAAGGGCTATCCTGAAGTGGCACTGCATTTTGTCAAGGATGAGAAAACTCGCTTTAGTCTGGCACTGGAGTGTGGAA ACATTGAGATTGCTCTGGAAGCAGCCAAAGCACTGGATGACAAGAACTGCTGGGAAAAGCTGGGAGAAGTGGCCCTGCTGCAGGGGAACC ACCAGATTGTGGAAATGTGCTATCAGCGTACCAAAAACTTTGACAAACTTTCCTTCCTGTATCTTATCACTGGCAACTTAGAAAAACTTC GCAAGATGATGAAGATTGCTGAGATCAGAAAGGACATGAGTGGCCACTATCAGAATGCCCTATACCTGGGTGATGTGTCAGAGCGTGTGC GGATCCTGAAGAACTGTGGACAGAAGTCCCTGGCCTATCTCACAGCTGCTACCCATGGCTTAGATGAAGAAGCTGAGAGCCTAAAGGAGA CATTTGACCCAGAGAAGGAGACAATCCCAGACATTGACCCTAATGCCAAGCTGCTCCAGCCACCTGCACCTATCATGCCATTGGATACCA ATTGGCCTTTATTGACTGTATCCAAAGGATTTTTTGAAGGCACCATTGCCAGCAAAGGGAAGGGAGGAGCACTGGCTGCTGACATTGACA TTGACACTGTTGGTACAGAGGGCTGGGGAGAGGATGCAGAGCTGCAGTTGGATGAAGATGGGTTTGTGGAGGCTACAGAAGGTTTGGGGG ATGATGCTCTTGGCAAGGGACAGGAAGAAGGAGGTGGCTGGGATGTAGAAGAAGATCTGGAGCTCCCTCCTGAGCTGGATATATCCCCTG GGGCAGCTGGTGGGGCTGAAGATGGTTTCTTTGTGCCCCCAACCAAGGGAACAAGTCCAACTCAGATCTGGTGTAATAACTCTCAGCTTC CAGTTGATCACATCCTGGCAGGCTCTTTCGAAACAGCCATGCGGCTCCTTCATGACCAAGTAGGGGTAATCCAGTTTGGCCCCTACAAGC AACTGTTCCTACAGACATACGCCCGAGGCCGCACAACCTATCAGGCTCTGCCCTGCCTACCCTCCATGTATGGCTATCCTAATCGCAACT GGAAGGATGCAGGGCTGAAGAATGGTGTACCAGCTGTGGGCCTGAAGCTTAATGACCTCATCCAACGGTTGCAGCTGTGCTACCAGCTCA CCACAGTTGGCAAATTTGAGGAGGCTGTGGAAAAATTCCGTTCCATCCTTCTCAGTGTGCCACTTCTTGTTGTGGACAATAAACAAGAGA TTGCAGAGGCCCAGCAGCTCATCACCATTTGCCGTGAGTACATTGTGGGTTTGTCCGTGGAGACAGAAAGGAAGAAGCTGCCCAAAGAGA CTCTAGAACAGCAGAAGCGCATCTGTGAGATGGCAGCCTATTTCACCCACTCAAACCTGCAGCCTGTGCACATGATCCTGGTGCTGCGTA CAGCCCTCAATCTGTTCTTCAAGCTCAAGAACTTCAAGACAGCTGCCACCTTTGCTCGGCGCCTACTAGAACTCGGGCCCAAGCCTGAGG TGGCCCAACAGACCCGAAAAATCCTGTCTGCCTGTGAGAAGAATCCCACAGATGCCTACCAGCTCAATTATGACATGCACAACCCCTTTG ACATTTGTGCTGCATCATATCGGCCCATCTACCGTGGAAAGCCAGTAGAAAAGTGTCCACTCAGTGGGGCCTGCTATTCCCCTGAGTTCA AAGGTCAAATCTGCAGGGTCACCACAGTGACAGAGATTGGCAAAGATGTGATTGGTTTAAGGATCAGTCCTCTGCAGTTTCGCTAAGGCC CCCTTTGTGTGCATGGGTCAGTCACCATATGTTCCCCCCAGAGAATGTGTCTATATCCTCCTTCTAACAGCACCTTCCCCCTGCAGCTAC TCTTCAGATCTGGCTCTCTGTACCCTAAAACCTAGTATCTTTTTCTCTTCTATGGAAAATCCGAAGGTCTAAACTTGACTTTTTTGAGGT CTTCTCAACTTGACTACAGTTGTGCTCATAATTGTCCTTGCCTTTCCAGCTTAATTATTTTAAGGAACAAATGAAAACTCTGGGCTGGGT GGAGTGGCTCATACCTGTAATCCCAGCACTTTGGGAGGCTACGGTGGGCAGATCATCTGAGGCCAGGAGTTCGAGACCTGCCTGGCCAAC ATGGCAACACCCCGTCTCTAATAAAAATATAAAAATTAGCCTGGCATGGTAGCATGCGCCTATAGTCCCAGCTGCTCAGGAGGCTGAGGC ATGAGAATCGCTTGAACCTAGGAGGTGGAGGTTGCATTCAACTGAGATCATACCACTTCATTCCAGCCTGGGTGACAGAGCAAGACTCTG TCTCAAAAAAAAAAAAAAGGAAAACTCTGTGATGGACATTTGTTTAGTAAATCCCTTCAGTATTTATCCCTCCTTTCCCCACAGCAGCTT TCTTTCCTGTCAACTAGAAAGGAGCAGGATGTAATAAATACATTTTGGTGTGACTAGGCCACACCAACTCTTAATCATCTCCCATTTTCC TTAGACATTTAAATTTCAAGGCAGGTACCCTCTGTGTACTCAGAAATTTGAAGAAGTTATTTGGTTTTCCAAAATGCACACTGCGGGTTA >In-frame_RASAL2_ENST00000367649_chr1_178269253_+_COPA_ENST00000368069_chr1_160310084_-_5355nt GAAGAAGGCGGCTCCGAGGAGGTGGGAGGGCGAGCCTCCCCTCCCGGGTTCTTCTGCGTCCTCTCCCGGGAGGGACCCACACACACCTGA GCCCGGACCCACCCTTGGTCGGGGCCACGCTGGATCCTCCTCCCGGCCTGGGTCCCGCCCGCCGACTGCAGGTGGGCTGCATCGCCCGAG CCTCGGGCAGTGGGCGACGGGGAAGGAGGTGAGAGGTGTCCGCGCCGGCTGCCGCTCGGGTCCCTGCCCTCGCTGCGCGCTCTCCTCCTC CCCTTACCGCAGGCAGGGCGCGGAGCCGCGCGCCAGCCCGCCCCGAAGCCGCCGCCTCGTCCCCCTCCCGCCTCGGGGCACCATGGAGCT CTCTCCGTCGTCCGGAGGAGCCGCGGAGGCGCTGTCCTGGCCGGAGATGTTCCCGGCGCTGGAGTCCGACTCGCCGCTGCCCCCGGAGGA CCTGGACGCGGTTGTCCCAGTCAGTGGAGCCGTCGCCGGTGGCATGTTGGATCGGATCCTTCTGGAGTCCGTGTGCCAGCAACAGAGCTG GGTCCGGGTGTACGATGTGAAAGGACCACCCACCCACCGTCTGTCTTGTGGTCAGTCACCCTACACCGAGACAACAACGTGGGAGCGGAA GTATTGCATCCTCACAGACAGCCAGTTGGTATTGCTCAACAAGGAGAAGGAGATACCTGTGGAAGGGGGACAGGAGCAGCAGACAGATTC CACCAAAGGGCGATGCCTGAGGAGAACTGTCAGTGTCCCTTCCGAGGGTCAGTTTCCCGAGTACCCACCAGAGGGCGCCACTAAACTGGG GCTCAGCTTTCACCCCAAAAGACCTTGGATCCTGACTAGTTTACATAATGGGGTCATCCAGTTATGGGACTATCGGATGTGCACTCTCAT TGACAAGTTTGATGAACATGATGGTCCAGTGCGAGGCATTGACTTCCATAAGCAGCAGCCACTGTTCGTCTCTGGAGGAGATGACTATAA GATTAAGGTTTGGAATTACAAGCTTCGGCGCTGTCTTTTCACATTGCTTGGGCACTTAGATTATATTCGCACCACGTTTTTTCATCATGA ATATCCCTGGATTCTGAGTGCCTCCGATGATCAGACCATCCGAGTGTGGAACTGGCAATCTAGAACCTGTGTTTGTGTGTTAACAGGGCA CAACCATTATGTGATGTGTGCTCAGTTCCACCCCACAGAAGACTTGGTAGTATCAGCCAGCCTGGACCAGACTGTGCGCGTTTGGGATAT TTCTGGTCTGAGGAAAAAAAACCTGTCCCCTGGTGCGGTGGAATCGGATGTGAGAGGAATAACTGGGGTTGATCTATTTGGAACTACAGA TGCAGTGGTGAAGCATGTACTAGAGGGTCACGATCGTGGAGTAAACTGGGCTGCCTTCCACCCCACTATGCCCCTTATTGTATCTGGGGC AGATGATCGTCAAGTGAAGATCTGGCGCATGAATGAATCAAAGGCATGGGAGGTTGATACCTGCCGGGGCCATTACAACAATGTATCTTG TGCCGTCTTCCACCCTCGCCAAGAGTTGATCCTCAGCAATTCTGAGGACAAGAGTATTCGAGTCTGGGATATGTCTAAGCGGACTGGGGT TCAGACTTTCCGCAGAGACCATGATCGTTTCTGGGTCCTAGCTGCTCACCCTAACCTTAACCTCTTTGCAGCAGGCCATGATGGTGGTAT GATTGTGTTTAAGCTGGAACGGGAACGGCCAGCCTATGCTGTTCATGGCAATATGCTACACTATGTCAAGGACCGATTCTTACGACAGCT GGATTTCAACAGCTCCAAAGATGTAGCTGTGATGCAGTTGCGGAGTGGTTCCAAGTTTCCAGTATTCAATATGTCATACAATCCAGCAGA AAATGCAGTCCTGCTTTGTACAAGAGCTAGCAATCTAGAGAATAGTACCTATGACCTGTACACCATCCCTAAAGATGCTGACTCCCAGAA TCCTGATGCGCCTGAAGGGAAACGATCCTCAGGCCTGACAGCCGTTTGGGTCGCTCGAAATCGGTTTGCTGTCCTAGATCGGATGCATTC GCTTCTGATCAAGAATCTGAAGAATGAGATCACCAAAAAGGTACAGGTGCCCAACTGTGATGAGATCTTCTATGCTGGCACAGGCAATCT CCTGCTTCGAGATGCGGACTCTATCACACTCTTTGACGTACAGCAGAAGCGGACTCTGGCATCTGTGAAGATTTCTAAAGTGAAATACGT TATCTGGTCAGCAGACATGTCACATGTAGCACTACTAGCCAAACACGAACACTCATGCCCTTTGCCTCTTACAGCCATTGTGATCTGTAA CCGCAAACTGGATGCTTTATGTAACATTCATGAGAACATTCGTGTCAAGAGTGGGGCCTGGGATGAGAGTGGGGTATTTATCTATACCAC AAGCAACCACATCAAATATGCTGTCACCACTGGGGACCACGGGATCATTCGAACTCTGGATTTACCCATCTATGTCACACGGGTGAAGGG CAACAATGTATACTGCCTAGACAGGGAGTGTCGTCCCCGGGTACTCACCATTGATCCCACTGAGTTCAAATTCAAGCTGGCCCTGATCAA CAGAAAATATGATGAGGTACTGCACATGGTGAGGAATGCCAAACTAGTTGGCCAGTCTATTATTGCTTATCTCCAGAAGAAGGGCTATCC TGAAGTGGCACTGCATTTTGTCAAGGATGAGAAAACTCGCTTTAGTCTGGCACTGGAGTGTGGAAACATTGAGATTGCTCTGGAAGCAGC CAAAGCACTGGATGACAAGAACTGCTGGGAAAAGCTGGGAGAAGTGGCCCTGCTGCAGGGGAACCACCAGATTGTGGAAATGTGCTATCA GCGTACCAAAAACTTTGACAAACTTTCCTTCCTGTATCTTATCACTGGCAACTTAGAAAAACTTCGCAAGATGATGAAGATTGCTGAGAT CAGAAAGGACATGAGTGGCCACTATCAGAATGCCCTATACCTGGGTGATGTGTCAGAGCGTGTGCGGATCCTGAAGAACTGTGGACAGAA GTCCCTGGCCTATCTCACAGCTGCTACCCATGGCTTAGATGAAGAAGCTGAGAGCCTAAAGGAGACATTTGACCCAGAGAAGGAGACAAT CCCAGACATTGACCCTAATGCCAAGCTGCTCCAGCCACCTGCACCTATCATGCCATTGGATACCAATTGGCCTTTATTGACTGTATCCAA AGGATTTTTTGAAGGCACCATTGCCAGCAAAGGGAAGGGAGGAGCACTGGCTGCTGACATTGACATTGACACTGTTGGTACAGAGGGCTG GGGAGAGGATGCAGAGCTGCAGTTGGATGAAGATGGGTTTGTGGAGGCTACAGAAGGTTTGGGGGATGATGCTCTTGGCAAGGGACAGGA AGAAGGAGGTGGCTGGGATGTAGAAGAAGATCTGGAGCTCCCTCCTGAGCTGGATATATCCCCTGGGGCAGCTGGTGGGGCTGAAGATGG TTTCTTTGTGCCCCCAACCAAGGGAACAAGTCCAACTCAGATCTGGTGTAATAACTCTCAGCTTCCAGTTGATCACATCCTGGCAGGCTC TTTCGAAACAGCCATGCGGCTCCTTCATGACCAAGTAGGGGTAATCCAGTTTGGCCCCTACAAGCAACTGTTCCTACAGACATACGCCCG AGGCCGCACAACCTATCAGGCTCTGCCCTGCCTACCCTCCATGTATGGCTATCCTAATCGCAACTGGAAGGATGCAGGGCTGAAGAATGG TGTACCAGCTGTGGGCCTGAAGCTTAATGACCTCATCCAACGGTTGCAGCTGTGCTACCAGCTCACCACAGTTGGCAAATTTGAGGAGGC TGTGGAAAAATTCCGTTCCATCCTTCTCAGTGTGCCACTTCTTGTTGTGGACAATAAACAAGAGATTGCAGAGGCCCAGCAGCTCATCAC CATTTGCCGTGAGTACATTGTGGGTTTGTCCGTGGAGACAGAAAGGAAGAAGCTGCCCAAAGAGACTCTAGAACAGCAGAAGCGCATCTG TGAGATGGCAGCCTATTTCACCCACTCAAACCTGCAGCCTGTGCACATGATCCTGGTGCTGCGTACAGCCCTCAATCTGTTCTTCAAGCT CAAGAACTTCAAGACAGCTGCCACCTTTGCTCGGCGCCTACTAGAACTCGGGCCCAAGCCTGAGGTGGCCCAACAGACCCGAAAAATCCT GTCTGCCTGTGAGAAGAATCCCACAGATGCCTACCAGCTCAATTATGACATGCACAACCCCTTTGACATTTGTGCTGCATCATATCGGCC CATCTACCGTGGAAAGCCAGTAGAAAAGTGTCCACTCAGTGGGGCCTGCTATTCCCCTGAGTTCAAAGGTCAAATCTGCAGGGTCACCAC AGTGACAGAGATTGGCAAAGATGTGATTGGTTTAAGGATCAGTCCTCTGCAGTTTCGCTAAGGCCCCCTTTGTGTGCATGGGTCAGTCAC CATATGTTCCCCCCAGAGAATGTGTCTATATCCTCCTTCTAACAGCACCTTCCCCCTGCAGCTACTCTTCAGATCTGGCTCTCTGTACCC TAAAACCTAGTATCTTTTTCTCTTCTATGGAAAATCCGAAGGTCTAAACTTGACTTTTTTGAGGTCTTCTCAACTTGACTACAGTTGTGC TCATAATTGTCCTTGCCTTTCCAGCTTAATTATTTTAAGGAACAAATGAAAACTCTGGGCTGGGTGGAGTGGCTCATACCTGTAATCCCA GCACTTTGGGAGGCTACGGTGGGCAGATCATCTGAGGCCAGGAGTTCGAGACCTGCCTGGCCAACATGGCAACACCCCGTCTCTAATAAA AATATAAAAATTAGCCTGGCATGGTAGCATGCGCCTATAGTCCCAGCTGCTCAGGAGGCTGAGGCATGAGAATCGCTTGAACCTAGGAGG TGGAGGTTGCATTCAACTGAGATCATACCACTTCATTCCAGCCTGGGTGACAGAGCAAGACTCTGTCTCAAAAAAAAAAAAAAGGAAAAC TCTGTGATGGACATTTGTTTAGTAAATCCCTTCAGTATTTATCCCTCCTTTCCCCACAGCAGCTTTCTTTCCTGTCAACTAGAAAGGAGC AGGATGTAATAAATACATTTTGGTGTGACTAGGCCACACCAACTCTTAATCATCTCCCATTTTCCTTAGACATTTAAATTTCAAGGCAGG TACCCTCTGTGTACTCAGAAATTTGAAGAAGTTATTTGGTTTTCCAAAATGCACACTGCGGGTTATTGATTTGTTCTTTACAACTATTGT >In-frame_RASAL2_ENST00000367649_chr1_178269253_+_COPA_ENST00000241704_chr1_160310084_-_5328nt GAAGAAGGCGGCTCCGAGGAGGTGGGAGGGCGAGCCTCCCCTCCCGGGTTCTTCTGCGTCCTCTCCCGGGAGGGACCCACACACACCTGA GCCCGGACCCACCCTTGGTCGGGGCCACGCTGGATCCTCCTCCCGGCCTGGGTCCCGCCCGCCGACTGCAGGTGGGCTGCATCGCCCGAG CCTCGGGCAGTGGGCGACGGGGAAGGAGGTGAGAGGTGTCCGCGCCGGCTGCCGCTCGGGTCCCTGCCCTCGCTGCGCGCTCTCCTCCTC CCCTTACCGCAGGCAGGGCGCGGAGCCGCGCGCCAGCCCGCCCCGAAGCCGCCGCCTCGTCCCCCTCCCGCCTCGGGGCACCATGGAGCT CTCTCCGTCGTCCGGAGGAGCCGCGGAGGCGCTGTCCTGGCCGGAGATGTTCCCGGCGCTGGAGTCCGACTCGCCGCTGCCCCCGGAGGA CCTGGACGCGGTTGTCCCAGTCAGTGGAGCCGTCGCCGGTGGCATGTTGGATCGGATCCTTCTGGAGTCCGTGTGCCAGCAACAGAGCTG GGTCCGGGTGTACGATGTGAAAGGACCACCCACCCACCGTCTGTCTTGTGGTCAGTCACCCTACACCGAGACAACAACGTGGGAGCGGAA GTATTGCATCCTCACAGACAGCCAGTTGGTATTGCTCAACAAGGAGAAGGAGATACCTGTGGAAGGGGGACAGGAGCAGCAGACAGATTC CACCAAAGGGCGATGCCTGAGGAGAACTGTCAGTGTCCCTTCCGAGGGTCAGTTTCCCGAGTACCCACCAGAGGGCGCCACTAAACTGGG GCTCAGCTTTCACCCCAAAAGACCTTGGATCCTGACTAGTTTACATAATGGGGTCATCCAGTTATGGGACTATCGGATGTGCACTCTCAT TGACAAGTTTGATGAACATGATGGTCCAGTGCGAGGCATTGACTTCCATAAGCAGCAGCCACTGTTCGTCTCTGGAGGAGATGACTATAA GATTAAGGTTTGGAATTACAAGCTTCGGCGCTGTCTTTTCACATTGCTTGGGCACTTAGATTATATTCGCACCACGTTTTTTCATCATGA ATATCCCTGGATTCTGAGTGCCTCCGATGATCAGACCATCCGAGTGTGGAACTGGCAATCTAGAACCTGTGTTTGTGTGTTAACAGGGCA CAACCATTATGTGATGTGTGCTCAGTTCCACCCCACAGAAGACTTGGTAGTATCAGCCAGCCTGGACCAGACTGTGCGCGTTTGGGATAT TTCTGGTCTGAGGAAAAAAAACCTGTCCCCTGGTGCGGTGGAATCGGATGTGAGAGGAATAACTGGGGTTGATCTATTTGGAACTACAGA TGCAGTGGTGAAGCATGTACTAGAGGGTCACGATCGTGGAGTAAACTGGGCTGCCTTCCACCCCACTATGCCCCTTATTGTATCTGGGGC AGATGATCGTCAAGTGAAGATCTGGCGCATGAATGAATCAAAGGCATGGGAGGTTGATACCTGCCGGGGCCATTACAACAATGTATCTTG TGCCGTCTTCCACCCTCGCCAAGAGTTGATCCTCAGCAATTCTGAGGACAAGAGTATTCGAGTCTGGGATATGTCTAAGCGGACTGGGGT TCAGACTTTCCGCAGAGACCATGATCGTTTCTGGGTCCTAGCTGCTCACCCTAACCTTAACCTCTTTGCAGCAGGCCATGATGGTGGTAT GATTGTGTTTAAGCTGGAACGGGAACGGCCAGCCTATGCTGTTCATGGCAATATGCTACACTATGTCAAGGACCGATTCTTACGACAGCT GGATTTCAACAGCTCCAAAGATGTAGCTGTGATGCAGTTGCGGAGTGGTTCCAAGTTTCCAGTATTCAATATGTCATACAATCCAGCAGA AAATGCAGTCCTGCTTTGTACAAGAGCTAGCAATCTAGAGAATAGTACCTATGACCTGTACACCATCCCTAAAGATGCTGACTCCCAGAA TCCTGATGCGCCTGAAGGGAAACGATCCTCAGGCCTGACAGCCGTTTGGGTCGCTCGAAATCGGTTTGCTGTCCTAGATCGGATGCATTC GCTTCTGATCAAGAATCTGAAGAATGAGATCACCAAAAAGGTACAGGTGCCCAACTGTGATGAGATCTTCTATGCTGGCACAGGCAATCT CCTGCTTCGAGATGCGGACTCTATCACACTCTTTGACGTACAGCAGAAGCGGACTCTGGCATCTGTGAAGATTTCTAAAGTGAAATACGT TATCTGGTCAGCAGACATGTCACATGTAGCACTACTAGCCAAACACGCCATTGTGATCTGTAACCGCAAACTGGATGCTTTATGTAACAT TCATGAGAACATTCGTGTCAAGAGTGGGGCCTGGGATGAGAGTGGGGTATTTATCTATACCACAAGCAACCACATCAAATATGCTGTCAC CACTGGGGACCACGGGATCATTCGAACTCTGGATTTACCCATCTATGTCACACGGGTGAAGGGCAACAATGTATACTGCCTAGACAGGGA GTGTCGTCCCCGGGTACTCACCATTGATCCCACTGAGTTCAAATTCAAGCTGGCCCTGATCAACAGAAAATATGATGAGGTACTGCACAT GGTGAGGAATGCCAAACTAGTTGGCCAGTCTATTATTGCTTATCTCCAGAAGAAGGGCTATCCTGAAGTGGCACTGCATTTTGTCAAGGA TGAGAAAACTCGCTTTAGTCTGGCACTGGAGTGTGGAAACATTGAGATTGCTCTGGAAGCAGCCAAAGCACTGGATGACAAGAACTGCTG GGAAAAGCTGGGAGAAGTGGCCCTGCTGCAGGGGAACCACCAGATTGTGGAAATGTGCTATCAGCGTACCAAAAACTTTGACAAACTTTC CTTCCTGTATCTTATCACTGGCAACTTAGAAAAACTTCGCAAGATGATGAAGATTGCTGAGATCAGAAAGGACATGAGTGGCCACTATCA GAATGCCCTATACCTGGGTGATGTGTCAGAGCGTGTGCGGATCCTGAAGAACTGTGGACAGAAGTCCCTGGCCTATCTCACAGCTGCTAC CCATGGCTTAGATGAAGAAGCTGAGAGCCTAAAGGAGACATTTGACCCAGAGAAGGAGACAATCCCAGACATTGACCCTAATGCCAAGCT GCTCCAGCCACCTGCACCTATCATGCCATTGGATACCAATTGGCCTTTATTGACTGTATCCAAAGGATTTTTTGAAGGCACCATTGCCAG CAAAGGGAAGGGAGGAGCACTGGCTGCTGACATTGACATTGACACTGTTGGTACAGAGGGCTGGGGAGAGGATGCAGAGCTGCAGTTGGA TGAAGATGGGTTTGTGGAGGCTACAGAAGGTTTGGGGGATGATGCTCTTGGCAAGGGACAGGAAGAAGGAGGTGGCTGGGATGTAGAAGA AGATCTGGAGCTCCCTCCTGAGCTGGATATATCCCCTGGGGCAGCTGGTGGGGCTGAAGATGGTTTCTTTGTGCCCCCAACCAAGGGAAC AAGTCCAACTCAGATCTGGTGTAATAACTCTCAGCTTCCAGTTGATCACATCCTGGCAGGCTCTTTCGAAACAGCCATGCGGCTCCTTCA TGACCAAGTAGGGGTAATCCAGTTTGGCCCCTACAAGCAACTGTTCCTACAGACATACGCCCGAGGCCGCACAACCTATCAGGCTCTGCC CTGCCTACCCTCCATGTATGGCTATCCTAATCGCAACTGGAAGGATGCAGGGCTGAAGAATGGTGTACCAGCTGTGGGCCTGAAGCTTAA TGACCTCATCCAACGGTTGCAGCTGTGCTACCAGCTCACCACAGTTGGCAAATTTGAGGAGGCTGTGGAAAAATTCCGTTCCATCCTTCT CAGTGTGCCACTTCTTGTTGTGGACAATAAACAAGAGATTGCAGAGGCCCAGCAGCTCATCACCATTTGCCGTGAGTACATTGTGGGTTT GTCCGTGGAGACAGAAAGGAAGAAGCTGCCCAAAGAGACTCTAGAACAGCAGAAGCGCATCTGTGAGATGGCAGCCTATTTCACCCACTC AAACCTGCAGCCTGTGCACATGATCCTGGTGCTGCGTACAGCCCTCAATCTGTTCTTCAAGCTCAAGAACTTCAAGACAGCTGCCACCTT TGCTCGGCGCCTACTAGAACTCGGGCCCAAGCCTGAGGTGGCCCAACAGACCCGAAAAATCCTGTCTGCCTGTGAGAAGAATCCCACAGA TGCCTACCAGCTCAATTATGACATGCACAACCCCTTTGACATTTGTGCTGCATCATATCGGCCCATCTACCGTGGAAAGCCAGTAGAAAA GTGTCCACTCAGTGGGGCCTGCTATTCCCCTGAGTTCAAAGGTCAAATCTGCAGGGTCACCACAGTGACAGAGATTGGCAAAGATGTGAT TGGTTTAAGGATCAGTCCTCTGCAGTTTCGCTAAGGCCCCCTTTGTGTGCATGGGTCAGTCACCATATGTTCCCCCCAGAGAATGTGTCT ATATCCTCCTTCTAACAGCACCTTCCCCCTGCAGCTACTCTTCAGATCTGGCTCTCTGTACCCTAAAACCTAGTATCTTTTTCTCTTCTA TGGAAAATCCGAAGGTCTAAACTTGACTTTTTTGAGGTCTTCTCAACTTGACTACAGTTGTGCTCATAATTGTCCTTGCCTTTCCAGCTT AATTATTTTAAGGAACAAATGAAAACTCTGGGCTGGGTGGAGTGGCTCATACCTGTAATCCCAGCACTTTGGGAGGCTACGGTGGGCAGA TCATCTGAGGCCAGGAGTTCGAGACCTGCCTGGCCAACATGGCAACACCCCGTCTCTAATAAAAATATAAAAATTAGCCTGGCATGGTAG CATGCGCCTATAGTCCCAGCTGCTCAGGAGGCTGAGGCATGAGAATCGCTTGAACCTAGGAGGTGGAGGTTGCATTCAACTGAGATCATA CCACTTCATTCCAGCCTGGGTGACAGAGCAAGACTCTGTCTCAAAAAAAAAAAAAAGGAAAACTCTGTGATGGACATTTGTTTAGTAAAT CCCTTCAGTATTTATCCCTCCTTTCCCCACAGCAGCTTTCTTTCCTGTCAACTAGAAAGGAGCAGGATGTAATAAATACATTTTGGTGTG ACTAGGCCACACCAACTCTTAATCATCTCCCATTTTCCTTAGACATTTAAATTTCAAGGCAGGTACCCTCTGTGTACTCAGAAATTTGAA GAAGTTATTTGGTTTTCCAAAATGCACACTGCGGGTTATTGATTTGTTCTTTACAACTATTGTTCTCATATTTCTCACACTAAATAAATC |
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FusionGenePPI for RASAL2_COPA |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| RASAL2 | YWHAG, SH3KBP1, UBC, LATS2, YWHAB, CSNK1A1, CSNK1E, CTAGE5, TRAF1, USHBP1, CEP128, TMEM17, SHC1, KCTD3, KIF13B, ZBTB21, KSR1, GIGYF1, CGN, LRFN1, DENND1A, SH3PXD2A, RTKN, SRGAP2, MAST3, EIF4E2, SIPA1L1, PPM1H, LIMA1, MAGI1, DENND4C, TESK2, DCLK1, ZNF638, NF1, HDAC4, CBY1, SRSF12, SYDE1, MAPKAP1, CDC25C, AGAP1, CDC25B, NADK, CDK16, GIGYF2, CAMSAP2, FAM110B, RALGPS2, USP21, KIAA1804, TIAM1, FAM53C, ANKRD34A, PHLDB2, LPIN3, PLEKHA7, KIF1C, INPP5E, TRIM25 | COPA | SLC25A11, COPE, COPB2, COPB1, ARFGAP1, PDGFRB, BET1L, USP49, ATG101, DDA1, SPG20, SIRT7, FBXO25, CDK2, SACM1L, SMN1, GEMIN2, DDX20, TMED10, COPG1, COPA, ARCN1, COPZ1, COPG2, FBXO6, UBXN6, LMAN1, SEC24C, SEC23A, SEPT9, VCAM1, ITGA4, CCT3, SEPT2, DHX38, TCP1, RPA3, RPA2, RPA1, NUDCD1, STAU1, SHMT2, MOV10, NXF1, CUL7, OBSL1, CCDC8, SUZ12, RNF2, EGFR, UNK, CCDC97, GCN1L1, KHDRBS1, SF3B1, SRSF3, TRIP10, SF3B3, NTRK1, HERC2, OFD1, MKS1, CEP128, NPHP1, TMEM237, TMEM17, XPO1, SORT1, XRCC3, MATR3, DSN1, FOXB1, WBP1, CD8A, CRY2, FOXL1, FOXQ1, FOXR1, SNW1, CDC5L, RNF126, POU5F1, FAM210A, ZNF746, PPM1G, WBP2, MTNR1B, DLD, PDHA1, SDHA, SOD1, EDEM3, BRCA1, YAP1, TES, MTF1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for RASAL2_COPA |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for RASAL2_COPA |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | COPA | C0003864 | Arthritis | 1 | CTD_human |
| Tgene | COPA | C0004364 | Autoimmune Diseases | 1 | CTD_human |
| Tgene | COPA | C0206062 | Lung Diseases, Interstitial | 1 | CTD_human |
| Tgene | COPA | C4225334 | AUTOIMMUNE INTERSTITIAL LUNG, JOINT, AND KIDNEY DISEASE | 1 | ORPHANET;UNIPROT |
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