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Fusion gene ID: 29707 |
FusionGeneSummary for PVR_ZNF233 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PVR_ZNF233 | Fusion gene ID: 29707 | Hgene | Tgene | Gene symbol | PVR | ZNF233 | Gene ID | 5817 | 353355 |
| Gene name | poliovirus receptor | zinc finger protein 233 | |
| Synonyms | CD155|HVED|NECL5|Necl-5|PVS|TAGE4 | - | |
| Cytomap | 19q13.31 | 19q13.31 | |
| Type of gene | protein-coding | protein-coding | |
| Description | poliovirus receptornectin-like protein 5 | zinc finger protein 233 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | P15151 | A6NK53 | |
| Ensembl transtripts involved in fusion gene | ENST00000425690, ENST00000344956, ENST00000403059, ENST00000406449, | ENST00000334152, ENST00000592581, ENST00000391958, ENST00000589522, | |
| Fusion gene scores | * DoF score | 7 X 7 X 5=245 | 3 X 2 X 2=12 |
| # samples | 7 | 3 | |
| ** MAII score | log2(7/245*10)=-1.8073549220576 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/12*10)=1.32192809488736 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: PVR [Title/Abstract] AND ZNF233 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | PVR | GO:0060370 | susceptibility to T cell mediated cytotoxicity | 15039383 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | UCEC | TCGA-B5-A5OE-01A | PVR | chr19 | 45150842 | + | ZNF233 | chr19 | 44768467 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000425690 | ENST00000334152 | PVR | chr19 | 45150842 | + | ZNF233 | chr19 | 44768467 | + |
| 5CDS-5UTR | ENST00000425690 | ENST00000592581 | PVR | chr19 | 45150842 | + | ZNF233 | chr19 | 44768467 | + |
| 5CDS-5UTR | ENST00000425690 | ENST00000391958 | PVR | chr19 | 45150842 | + | ZNF233 | chr19 | 44768467 | + |
| 5CDS-5UTR | ENST00000425690 | ENST00000589522 | PVR | chr19 | 45150842 | + | ZNF233 | chr19 | 44768467 | + |
| In-frame | ENST00000344956 | ENST00000334152 | PVR | chr19 | 45150842 | + | ZNF233 | chr19 | 44768467 | + |
| 5CDS-5UTR | ENST00000344956 | ENST00000592581 | PVR | chr19 | 45150842 | + | ZNF233 | chr19 | 44768467 | + |
| 5CDS-5UTR | ENST00000344956 | ENST00000391958 | PVR | chr19 | 45150842 | + | ZNF233 | chr19 | 44768467 | + |
| 5CDS-5UTR | ENST00000344956 | ENST00000589522 | PVR | chr19 | 45150842 | + | ZNF233 | chr19 | 44768467 | + |
| In-frame | ENST00000403059 | ENST00000334152 | PVR | chr19 | 45150842 | + | ZNF233 | chr19 | 44768467 | + |
| 5CDS-5UTR | ENST00000403059 | ENST00000592581 | PVR | chr19 | 45150842 | + | ZNF233 | chr19 | 44768467 | + |
| 5CDS-5UTR | ENST00000403059 | ENST00000391958 | PVR | chr19 | 45150842 | + | ZNF233 | chr19 | 44768467 | + |
| 5CDS-5UTR | ENST00000403059 | ENST00000589522 | PVR | chr19 | 45150842 | + | ZNF233 | chr19 | 44768467 | + |
| In-frame | ENST00000406449 | ENST00000334152 | PVR | chr19 | 45150842 | + | ZNF233 | chr19 | 44768467 | + |
| 5CDS-5UTR | ENST00000406449 | ENST00000592581 | PVR | chr19 | 45150842 | + | ZNF233 | chr19 | 44768467 | + |
| 5CDS-5UTR | ENST00000406449 | ENST00000391958 | PVR | chr19 | 45150842 | + | ZNF233 | chr19 | 44768467 | + |
| 5CDS-5UTR | ENST00000406449 | ENST00000589522 | PVR | chr19 | 45150842 | + | ZNF233 | chr19 | 44768467 | + |
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FusionProtFeatures for PVR_ZNF233 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| PVR | ZNF233 |
| Mediates NK cell adhesion and triggers NK cell effectorfunctions. Binds two different NK cell receptors: CD96 and CD226.These interactions accumulates at the cell-cell contact site,leading to the formation of a mature immunological synapse betweenNK cell and target cell. This may trigger adhesion and secretionof lytic granules and IFN-gamma and activate cytoxicity ofactivated NK cells. May also promote NK cell-target cell modularexchange, and PVR transfer to the NK cell. This transfer is moreimportant in some tumor cells expressing a lot of PVR, and maytrigger fratricide NK cell activation, providing tumors with amechanism of immunoevasion. Plays a role in mediating tumor cellinvasion and migration. {ECO:0000269|PubMed:15471548,ECO:0000269|PubMed:15607800}. (Microbial infection) Acts as a receptor for poliovirus.May play a role in axonal transport of poliovirus, by targetingvirion-PVR-containing endocytic vesicles to the microtubularnetwork through interaction with DYNLT1. This interaction woulddrive the virus-containing vesicle to the axonal retrogradetransport. {ECO:0000269|PubMed:2538245}. (Microbial infection) Acts as a receptor forPseudorabies virus. {ECO:0000269|PubMed:9616127}. (Microbial infection) Is prevented to reach cell surfaceupon infection by Human cytomegalovirus /HHV-5, presumably toescape immune recognition of infected cell by NK cells.{ECO:0000269|PubMed:15640804}. | May be involved in transcriptional regulation. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | PVR | chr19:45150842 | chr19:44768467 | ENST00000344956 | + | 2 | 7 | 24_139 | 142 | 365 | Domain | Note=Ig-like V-type |
| Hgene | PVR | chr19:45150842 | chr19:44768467 | ENST00000403059 | + | 2 | 8 | 24_139 | 142 | 373 | Domain | Note=Ig-like V-type |
| Hgene | PVR | chr19:45150842 | chr19:44768467 | ENST00000406449 | + | 2 | 6 | 24_139 | 142 | 393 | Domain | Note=Ig-like V-type |
| Hgene | PVR | chr19:45150842 | chr19:44768467 | ENST00000425690 | + | 2 | 8 | 24_139 | 142 | 418 | Domain | Note=Ig-like V-type |
| Tgene | >ZNF233 | chr19:45150842 | chr19:44768467 | ENST00000391958 | + | 0 | 5 | 8_79 | -16 | 671 | Domain | KRAB |
| Tgene | >ZNF233 | chr19:45150842 | chr19:44768467 | ENST00000391958 | + | 0 | 5 | 258_280 | -16 | 671 | Zinc finger | C2H2-type 1%3B degenerate |
| Tgene | >ZNF233 | chr19:45150842 | chr19:44768467 | ENST00000391958 | + | 0 | 5 | 311_336 | -16 | 671 | Zinc finger | C2H2-type 2%3B degenerate |
| Tgene | >ZNF233 | chr19:45150842 | chr19:44768467 | ENST00000391958 | + | 0 | 5 | 342_364 | -16 | 671 | Zinc finger | C2H2-type 3%3B degenerate |
| Tgene | >ZNF233 | chr19:45150842 | chr19:44768467 | ENST00000391958 | + | 0 | 5 | 370_392 | -16 | 671 | Zinc finger | C2H2-type 4%3B degenerate |
| Tgene | >ZNF233 | chr19:45150842 | chr19:44768467 | ENST00000391958 | + | 0 | 5 | 398_420 | -16 | 671 | Zinc finger | C2H2-type 5%3B degenerate |
| Tgene | >ZNF233 | chr19:45150842 | chr19:44768467 | ENST00000391958 | + | 0 | 5 | 452_474 | -16 | 671 | Zinc finger | C2H2-type 6 |
| Tgene | >ZNF233 | chr19:45150842 | chr19:44768467 | ENST00000391958 | + | 0 | 5 | 480_502 | -16 | 671 | Zinc finger | C2H2-type 7 |
| Tgene | >ZNF233 | chr19:45150842 | chr19:44768467 | ENST00000391958 | + | 0 | 5 | 508_530 | -16 | 671 | Zinc finger | C2H2-type 8 |
| Tgene | >ZNF233 | chr19:45150842 | chr19:44768467 | ENST00000391958 | + | 0 | 5 | 536_558 | -16 | 671 | Zinc finger | C2H2-type 9 |
| Tgene | >ZNF233 | chr19:45150842 | chr19:44768467 | ENST00000391958 | + | 0 | 5 | 564_586 | -16 | 671 | Zinc finger | C2H2-type 10 |
| Tgene | >ZNF233 | chr19:45150842 | chr19:44768467 | ENST00000391958 | + | 0 | 5 | 592_614 | -16 | 671 | Zinc finger | C2H2-type 11 |
| Tgene | >ZNF233 | chr19:45150842 | chr19:44768467 | ENST00000391958 | + | 0 | 5 | 620_642 | -16 | 671 | Zinc finger | C2H2-type 12 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >PVR | chr19:45150842 | chr19:44768467 | ENST00000344956 | + | 2 | 7 | 145_237 | 142 | 365 | Domain | Note=Ig-like C2-type 1 |
| Hgene | >PVR | chr19:45150842 | chr19:44768467 | ENST00000344956 | + | 2 | 7 | 244_328 | 142 | 365 | Domain | Note=Ig-like C2-type 2 |
| Hgene | >PVR | chr19:45150842 | chr19:44768467 | ENST00000403059 | + | 2 | 8 | 145_237 | 142 | 373 | Domain | Note=Ig-like C2-type 1 |
| Hgene | >PVR | chr19:45150842 | chr19:44768467 | ENST00000403059 | + | 2 | 8 | 244_328 | 142 | 373 | Domain | Note=Ig-like C2-type 2 |
| Hgene | >PVR | chr19:45150842 | chr19:44768467 | ENST00000406449 | + | 2 | 6 | 145_237 | 142 | 393 | Domain | Note=Ig-like C2-type 1 |
| Hgene | >PVR | chr19:45150842 | chr19:44768467 | ENST00000406449 | + | 2 | 6 | 244_328 | 142 | 393 | Domain | Note=Ig-like C2-type 2 |
| Hgene | >PVR | chr19:45150842 | chr19:44768467 | ENST00000425690 | + | 2 | 8 | 145_237 | 142 | 418 | Domain | Note=Ig-like C2-type 1 |
| Hgene | >PVR | chr19:45150842 | chr19:44768467 | ENST00000425690 | + | 2 | 8 | 244_328 | 142 | 418 | Domain | Note=Ig-like C2-type 2 |
| Hgene | >PVR | chr19:45150842 | chr19:44768467 | ENST00000344956 | + | 2 | 7 | 396_401 | 142 | 365 | Motif | Note=ITIM motif |
| Hgene | >PVR | chr19:45150842 | chr19:44768467 | ENST00000403059 | + | 2 | 8 | 396_401 | 142 | 373 | Motif | Note=ITIM motif |
| Hgene | >PVR | chr19:45150842 | chr19:44768467 | ENST00000406449 | + | 2 | 6 | 396_401 | 142 | 393 | Motif | Note=ITIM motif |
| Hgene | >PVR | chr19:45150842 | chr19:44768467 | ENST00000425690 | + | 2 | 8 | 396_401 | 142 | 418 | Motif | Note=ITIM motif |
| Hgene | >PVR | chr19:45150842 | chr19:44768467 | ENST00000344956 | + | 2 | 7 | 368_372 | 142 | 365 | Region | Note=DYNLT1 binding |
| Hgene | >PVR | chr19:45150842 | chr19:44768467 | ENST00000403059 | + | 2 | 8 | 368_372 | 142 | 373 | Region | Note=DYNLT1 binding |
| Hgene | >PVR | chr19:45150842 | chr19:44768467 | ENST00000406449 | + | 2 | 6 | 368_372 | 142 | 393 | Region | Note=DYNLT1 binding |
| Hgene | >PVR | chr19:45150842 | chr19:44768467 | ENST00000425690 | + | 2 | 8 | 368_372 | 142 | 418 | Region | Note=DYNLT1 binding |
| Hgene | >PVR | chr19:45150842 | chr19:44768467 | ENST00000344956 | + | 2 | 7 | 21_343 | 142 | 365 | Topological domain | Extracellular |
| Hgene | >PVR | chr19:45150842 | chr19:44768467 | ENST00000344956 | + | 2 | 7 | 368_417 | 142 | 365 | Topological domain | Cytoplasmic |
| Hgene | >PVR | chr19:45150842 | chr19:44768467 | ENST00000403059 | + | 2 | 8 | 21_343 | 142 | 373 | Topological domain | Extracellular |
| Hgene | >PVR | chr19:45150842 | chr19:44768467 | ENST00000403059 | + | 2 | 8 | 368_417 | 142 | 373 | Topological domain | Cytoplasmic |
| Hgene | >PVR | chr19:45150842 | chr19:44768467 | ENST00000406449 | + | 2 | 6 | 21_343 | 142 | 393 | Topological domain | Extracellular |
| Hgene | >PVR | chr19:45150842 | chr19:44768467 | ENST00000406449 | + | 2 | 6 | 368_417 | 142 | 393 | Topological domain | Cytoplasmic |
| Hgene | >PVR | chr19:45150842 | chr19:44768467 | ENST00000425690 | + | 2 | 8 | 21_343 | 142 | 418 | Topological domain | Extracellular |
| Hgene | >PVR | chr19:45150842 | chr19:44768467 | ENST00000425690 | + | 2 | 8 | 368_417 | 142 | 418 | Topological domain | Cytoplasmic |
| Hgene | >PVR | chr19:45150842 | chr19:44768467 | ENST00000344956 | + | 2 | 7 | 344_367 | 142 | 365 | Transmembrane | Helical |
| Hgene | >PVR | chr19:45150842 | chr19:44768467 | ENST00000403059 | + | 2 | 8 | 344_367 | 142 | 373 | Transmembrane | Helical |
| Hgene | >PVR | chr19:45150842 | chr19:44768467 | ENST00000406449 | + | 2 | 6 | 344_367 | 142 | 393 | Transmembrane | Helical |
| Hgene | >PVR | chr19:45150842 | chr19:44768467 | ENST00000425690 | + | 2 | 8 | 344_367 | 142 | 418 | Transmembrane | Helical |
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FusionGeneSequence for PVR_ZNF233 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_PVR_ENST00000425690_chr19_45150842_+_ZNF233_ENST00000334152_chr19_44768467_+_708aa MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTWARHGESGSMAVFHQTQGPSYSESK RLEFVAARLGAELRNASLRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLVLPSQDPALPQKEQEKMTKFQLLAIRLRLHLLDVVGDG DIQGCGCGLHQGGAGVAGPCPEKAVPRCDAGELQEPAVSGLSTLQTRCDITVGKRRQASDDGDRNPRRWVFRQRIAHQHDDHGVHKREKA FSHNNCGKDCVKESSQHSIIQSGEQTSDENGKGLSVGSNLELHQQLHLRDKPHVNVEYGKGIGYSSGLPRHQCFHIGEKCYRNGDSGEGF SQGSHLQPHQRVSTGENLYRCQVYARSSNQNSCLPSHELTHPGEKLCTCGRCGKGFHHSLDFDIHCVDSAGERACKCDVYDKGFSQTSQL QAHQRGHSRDKTYKWEVSDRIFNRNSGLHQRVHTGEKPYKCEVCDKGFSKASNLQAHQRIHTGEKPYKCDVCDKNFSRNSHLQAHQRVHT GEKPYKCDTCGKDFSQISHLQAHQRVHKGEKPYKCETCGKGFSQSSHLQDHQQVHTGENPYKCDVCGKGFSWSSHLQAHQRVHTGEKPYK >In-frame_PVR_ENST00000344956_chr19_45150842_+_ZNF233_ENST00000334152_chr19_44768467_+_708aa MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTWARHGESGSMAVFHQTQGPSYSESK RLEFVAARLGAELRNASLRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLVLPSQDPALPQKEQEKMTKFQLLAIRLRLHLLDVVGDG DIQGCGCGLHQGGAGVAGPCPEKAVPRCDAGELQEPAVSGLSTLQTRCDITVGKRRQASDDGDRNPRRWVFRQRIAHQHDDHGVHKREKA FSHNNCGKDCVKESSQHSIIQSGEQTSDENGKGLSVGSNLELHQQLHLRDKPHVNVEYGKGIGYSSGLPRHQCFHIGEKCYRNGDSGEGF SQGSHLQPHQRVSTGENLYRCQVYARSSNQNSCLPSHELTHPGEKLCTCGRCGKGFHHSLDFDIHCVDSAGERACKCDVYDKGFSQTSQL QAHQRGHSRDKTYKWEVSDRIFNRNSGLHQRVHTGEKPYKCEVCDKGFSKASNLQAHQRIHTGEKPYKCDVCDKNFSRNSHLQAHQRVHT GEKPYKCDTCGKDFSQISHLQAHQRVHKGEKPYKCETCGKGFSQSSHLQDHQQVHTGENPYKCDVCGKGFSWSSHLQAHQRVHTGEKPYK >In-frame_PVR_ENST00000403059_chr19_45150842_+_ZNF233_ENST00000334152_chr19_44768467_+_708aa MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTWARHGESGSMAVFHQTQGPSYSESK RLEFVAARLGAELRNASLRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLVLPSQDPALPQKEQEKMTKFQLLAIRLRLHLLDVVGDG DIQGCGCGLHQGGAGVAGPCPEKAVPRCDAGELQEPAVSGLSTLQTRCDITVGKRRQASDDGDRNPRRWVFRQRIAHQHDDHGVHKREKA FSHNNCGKDCVKESSQHSIIQSGEQTSDENGKGLSVGSNLELHQQLHLRDKPHVNVEYGKGIGYSSGLPRHQCFHIGEKCYRNGDSGEGF SQGSHLQPHQRVSTGENLYRCQVYARSSNQNSCLPSHELTHPGEKLCTCGRCGKGFHHSLDFDIHCVDSAGERACKCDVYDKGFSQTSQL QAHQRGHSRDKTYKWEVSDRIFNRNSGLHQRVHTGEKPYKCEVCDKGFSKASNLQAHQRIHTGEKPYKCDVCDKNFSRNSHLQAHQRVHT GEKPYKCDTCGKDFSQISHLQAHQRVHKGEKPYKCETCGKGFSQSSHLQDHQQVHTGENPYKCDVCGKGFSWSSHLQAHQRVHTGEKPYK >In-frame_PVR_ENST00000406449_chr19_45150842_+_ZNF233_ENST00000334152_chr19_44768467_+_708aa MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTWARHGESGSMAVFHQTQGPSYSESK RLEFVAARLGAELRNASLRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLVLPSQDPALPQKEQEKMTKFQLLAIRLRLHLLDVVGDG DIQGCGCGLHQGGAGVAGPCPEKAVPRCDAGELQEPAVSGLSTLQTRCDITVGKRRQASDDGDRNPRRWVFRQRIAHQHDDHGVHKREKA FSHNNCGKDCVKESSQHSIIQSGEQTSDENGKGLSVGSNLELHQQLHLRDKPHVNVEYGKGIGYSSGLPRHQCFHIGEKCYRNGDSGEGF SQGSHLQPHQRVSTGENLYRCQVYARSSNQNSCLPSHELTHPGEKLCTCGRCGKGFHHSLDFDIHCVDSAGERACKCDVYDKGFSQTSQL QAHQRGHSRDKTYKWEVSDRIFNRNSGLHQRVHTGEKPYKCEVCDKGFSKASNLQAHQRIHTGEKPYKCDVCDKNFSRNSHLQAHQRVHT GEKPYKCDTCGKDFSQISHLQAHQRVHKGEKPYKCETCGKGFSQSSHLQDHQQVHTGENPYKCDVCGKGFSWSSHLQAHQRVHTGEKPYK |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_PVR_ENST00000425690_chr19_45150842_+_ZNF233_ENST00000334152_chr19_44768467_+_2124nt ATGGCCCGAGCCATGGCCGCCGCGTGGCCGCTGCTGCTGGTGGCGCTACTGGTGCTGTCCTGGCCACCCCCAGGAACCGGGGACGTCGTC GTGCAGGCGCCCACCCAGGTGCCCGGCTTCTTGGGCGACTCCGTGACGCTGCCCTGCTACCTACAGGTGCCCAACATGGAGGTGACGCAT GTGTCACAGCTGACTTGGGCGCGGCATGGTGAATCTGGCAGCATGGCCGTCTTCCACCAAACGCAGGGCCCCAGCTATTCGGAGTCCAAA CGGCTGGAATTCGTGGCAGCCAGACTGGGCGCGGAGCTGCGGAATGCCTCGCTGAGGATGTTCGGGTTGCGCGTAGAGGATGAAGGCAAC TACACCTGCCTGTTCGTCACGTTCCCGCAGGGCAGCAGGAGCGTGGATATCTGGCTCCGAGTGCTTGTTCTGCCTTCCCAGGACCCTGCC CTTCCCCAGAAGGAGCAGGAGAAAATGACCAAGTTTCAGTTATTGGCCATAAGATTGAGATTACATCTGCTTGATGTTGTAGGAGATGGT GACATTCAAGGATGTGGCTGTGGTCTTCACCAGGGAGGAGCTGGGGTTGCTGGACCTTGCCCAGAGAAAGCTGTACCAAGATGTGATGCT GGAGAACTTCAGGAACCTGCTGTCAGTGGGCTATCAACCCTTCAAACTAGATGTGATATTACAGTTGGGAAAAGAAGACAAGCTTCGGAT GATGGAGACAGAAATCCAAGGAGATGGGTGTTCAGGCAAAGAATTGCTCATCAACATGATGATCATGGAGTACACAAAAGAGAGAAAGCT TTTAGCCACAATAATTGTGGAAAAGACTGTGTGAAGGAATCATCCCAGCATAGCATAATCCAATCAGGAGAGCAAACCTCTGATGAAAAT GGAAAAGGCTTAAGTGTTGGCTCTAATCTTGAACTTCACCAGCAACTACACTTAAGAGACAAGCCTCATGTAAATGTTGAGTACGGGAAG GGCATAGGTTACAGCTCAGGGCTTCCCAGGCATCAGTGTTTCCACATAGGAGAGAAATGCTATAGGAATGGTGACAGTGGTGAGGGCTTC AGTCAGGGCTCACATCTGCAACCTCATCAGAGAGTCAGCACAGGAGAGAACCTCTACAGATGTCAGGTATATGCCCGGAGCTCCAACCAG AACTCCTGTCTTCCCTCTCATGAGCTTACTCACCCAGGAGAGAAGTTGTGTACATGTGGCAGGTGTGGGAAGGGCTTCCATCATAGCTTA GATTTTGACATTCACTGTGTAGACAGTGCTGGAGAGAGAGCCTGTAAATGTGATGTATATGATAAAGGCTTCAGTCAGACATCACAACTT CAAGCCCATCAGAGAGGTCACTCTAGAGACAAGACATACAAATGGGAAGTAAGTGACAGGATATTTAATAGGAATTCTGGTCTTCACCAG AGAGTTCACACTGGAGAGAAACCATATAAATGTGAGGTATGTGATAAGGGCTTCAGTAAGGCCTCAAATCTTCAAGCCCATCAGAGAATC CACACTGGAGAGAAACCCTACAAATGTGATGTGTGTGATAAGAACTTCAGCCGTAATTCCCACCTTCAGGCCCATCAGAGAGTCCATACA GGAGAGAAACCCTACAAATGTGACACATGTGGGAAGGACTTCAGTCAGATCTCTCATCTTCAGGCCCATCAGAGAGTTCACAAAGGAGAG AAGCCATACAAATGTGAGACATGTGGGAAGGGCTTTAGTCAGAGTTCGCATCTCCAAGACCATCAGCAAGTCCATACTGGAGAGAATCCC TACAAATGTGATGTGTGTGGGAAAGGCTTCAGTTGGAGTTCACATCTTCAAGCCCATCAGAGAGTCCACACAGGAGAGAAACCATACAAA TGTGAAGAATGTAGGAAAGGCTTCATCTGGAACTCATATCTTCATGTTCATCAGAGGATCCACACGGGAGAGAAACCCTATAAATGTGGC ATGTGTGGTAAGAGCTTCAGTCAGACTTCACATCTTCAAGCCCATCAGAGAGTCCATACTGGAGAGAAACCATACAAATGTTTTGTGTGT >In-frame_PVR_ENST00000344956_chr19_45150842_+_ZNF233_ENST00000334152_chr19_44768467_+_2124nt ATGGCCCGAGCCATGGCCGCCGCGTGGCCGCTGCTGCTGGTGGCGCTACTGGTGCTGTCCTGGCCACCCCCAGGAACCGGGGACGTCGTC GTGCAGGCGCCCACCCAGGTGCCCGGCTTCTTGGGCGACTCCGTGACGCTGCCCTGCTACCTACAGGTGCCCAACATGGAGGTGACGCAT GTGTCACAGCTGACTTGGGCGCGGCATGGTGAATCTGGCAGCATGGCCGTCTTCCACCAAACGCAGGGCCCCAGCTATTCGGAGTCCAAA CGGCTGGAATTCGTGGCAGCCAGACTGGGCGCGGAGCTGCGGAATGCCTCGCTGAGGATGTTCGGGTTGCGCGTAGAGGATGAAGGCAAC TACACCTGCCTGTTCGTCACGTTCCCGCAGGGCAGCAGGAGCGTGGATATCTGGCTCCGAGTGCTTGTTCTGCCTTCCCAGGACCCTGCC CTTCCCCAGAAGGAGCAGGAGAAAATGACCAAGTTTCAGTTATTGGCCATAAGATTGAGATTACATCTGCTTGATGTTGTAGGAGATGGT GACATTCAAGGATGTGGCTGTGGTCTTCACCAGGGAGGAGCTGGGGTTGCTGGACCTTGCCCAGAGAAAGCTGTACCAAGATGTGATGCT GGAGAACTTCAGGAACCTGCTGTCAGTGGGCTATCAACCCTTCAAACTAGATGTGATATTACAGTTGGGAAAAGAAGACAAGCTTCGGAT GATGGAGACAGAAATCCAAGGAGATGGGTGTTCAGGCAAAGAATTGCTCATCAACATGATGATCATGGAGTACACAAAAGAGAGAAAGCT TTTAGCCACAATAATTGTGGAAAAGACTGTGTGAAGGAATCATCCCAGCATAGCATAATCCAATCAGGAGAGCAAACCTCTGATGAAAAT GGAAAAGGCTTAAGTGTTGGCTCTAATCTTGAACTTCACCAGCAACTACACTTAAGAGACAAGCCTCATGTAAATGTTGAGTACGGGAAG GGCATAGGTTACAGCTCAGGGCTTCCCAGGCATCAGTGTTTCCACATAGGAGAGAAATGCTATAGGAATGGTGACAGTGGTGAGGGCTTC AGTCAGGGCTCACATCTGCAACCTCATCAGAGAGTCAGCACAGGAGAGAACCTCTACAGATGTCAGGTATATGCCCGGAGCTCCAACCAG AACTCCTGTCTTCCCTCTCATGAGCTTACTCACCCAGGAGAGAAGTTGTGTACATGTGGCAGGTGTGGGAAGGGCTTCCATCATAGCTTA GATTTTGACATTCACTGTGTAGACAGTGCTGGAGAGAGAGCCTGTAAATGTGATGTATATGATAAAGGCTTCAGTCAGACATCACAACTT CAAGCCCATCAGAGAGGTCACTCTAGAGACAAGACATACAAATGGGAAGTAAGTGACAGGATATTTAATAGGAATTCTGGTCTTCACCAG AGAGTTCACACTGGAGAGAAACCATATAAATGTGAGGTATGTGATAAGGGCTTCAGTAAGGCCTCAAATCTTCAAGCCCATCAGAGAATC CACACTGGAGAGAAACCCTACAAATGTGATGTGTGTGATAAGAACTTCAGCCGTAATTCCCACCTTCAGGCCCATCAGAGAGTCCATACA GGAGAGAAACCCTACAAATGTGACACATGTGGGAAGGACTTCAGTCAGATCTCTCATCTTCAGGCCCATCAGAGAGTTCACAAAGGAGAG AAGCCATACAAATGTGAGACATGTGGGAAGGGCTTTAGTCAGAGTTCGCATCTCCAAGACCATCAGCAAGTCCATACTGGAGAGAATCCC TACAAATGTGATGTGTGTGGGAAAGGCTTCAGTTGGAGTTCACATCTTCAAGCCCATCAGAGAGTCCACACAGGAGAGAAACCATACAAA TGTGAAGAATGTAGGAAAGGCTTCATCTGGAACTCATATCTTCATGTTCATCAGAGGATCCACACGGGAGAGAAACCCTATAAATGTGGC ATGTGTGGTAAGAGCTTCAGTCAGACTTCACATCTTCAAGCCCATCAGAGAGTCCATACTGGAGAGAAACCATACAAATGTTTTGTGTGT >In-frame_PVR_ENST00000403059_chr19_45150842_+_ZNF233_ENST00000334152_chr19_44768467_+_2124nt ATGGCCCGAGCCATGGCCGCCGCGTGGCCGCTGCTGCTGGTGGCGCTACTGGTGCTGTCCTGGCCACCCCCAGGAACCGGGGACGTCGTC GTGCAGGCGCCCACCCAGGTGCCCGGCTTCTTGGGCGACTCCGTGACGCTGCCCTGCTACCTACAGGTGCCCAACATGGAGGTGACGCAT GTGTCACAGCTGACTTGGGCGCGGCATGGTGAATCTGGCAGCATGGCCGTCTTCCACCAAACGCAGGGCCCCAGCTATTCGGAGTCCAAA CGGCTGGAATTCGTGGCAGCCAGACTGGGCGCGGAGCTGCGGAATGCCTCGCTGAGGATGTTCGGGTTGCGCGTAGAGGATGAAGGCAAC TACACCTGCCTGTTCGTCACGTTCCCGCAGGGCAGCAGGAGCGTGGATATCTGGCTCCGAGTGCTTGTTCTGCCTTCCCAGGACCCTGCC CTTCCCCAGAAGGAGCAGGAGAAAATGACCAAGTTTCAGTTATTGGCCATAAGATTGAGATTACATCTGCTTGATGTTGTAGGAGATGGT GACATTCAAGGATGTGGCTGTGGTCTTCACCAGGGAGGAGCTGGGGTTGCTGGACCTTGCCCAGAGAAAGCTGTACCAAGATGTGATGCT GGAGAACTTCAGGAACCTGCTGTCAGTGGGCTATCAACCCTTCAAACTAGATGTGATATTACAGTTGGGAAAAGAAGACAAGCTTCGGAT GATGGAGACAGAAATCCAAGGAGATGGGTGTTCAGGCAAAGAATTGCTCATCAACATGATGATCATGGAGTACACAAAAGAGAGAAAGCT TTTAGCCACAATAATTGTGGAAAAGACTGTGTGAAGGAATCATCCCAGCATAGCATAATCCAATCAGGAGAGCAAACCTCTGATGAAAAT GGAAAAGGCTTAAGTGTTGGCTCTAATCTTGAACTTCACCAGCAACTACACTTAAGAGACAAGCCTCATGTAAATGTTGAGTACGGGAAG GGCATAGGTTACAGCTCAGGGCTTCCCAGGCATCAGTGTTTCCACATAGGAGAGAAATGCTATAGGAATGGTGACAGTGGTGAGGGCTTC AGTCAGGGCTCACATCTGCAACCTCATCAGAGAGTCAGCACAGGAGAGAACCTCTACAGATGTCAGGTATATGCCCGGAGCTCCAACCAG AACTCCTGTCTTCCCTCTCATGAGCTTACTCACCCAGGAGAGAAGTTGTGTACATGTGGCAGGTGTGGGAAGGGCTTCCATCATAGCTTA GATTTTGACATTCACTGTGTAGACAGTGCTGGAGAGAGAGCCTGTAAATGTGATGTATATGATAAAGGCTTCAGTCAGACATCACAACTT CAAGCCCATCAGAGAGGTCACTCTAGAGACAAGACATACAAATGGGAAGTAAGTGACAGGATATTTAATAGGAATTCTGGTCTTCACCAG AGAGTTCACACTGGAGAGAAACCATATAAATGTGAGGTATGTGATAAGGGCTTCAGTAAGGCCTCAAATCTTCAAGCCCATCAGAGAATC CACACTGGAGAGAAACCCTACAAATGTGATGTGTGTGATAAGAACTTCAGCCGTAATTCCCACCTTCAGGCCCATCAGAGAGTCCATACA GGAGAGAAACCCTACAAATGTGACACATGTGGGAAGGACTTCAGTCAGATCTCTCATCTTCAGGCCCATCAGAGAGTTCACAAAGGAGAG AAGCCATACAAATGTGAGACATGTGGGAAGGGCTTTAGTCAGAGTTCGCATCTCCAAGACCATCAGCAAGTCCATACTGGAGAGAATCCC TACAAATGTGATGTGTGTGGGAAAGGCTTCAGTTGGAGTTCACATCTTCAAGCCCATCAGAGAGTCCACACAGGAGAGAAACCATACAAA TGTGAAGAATGTAGGAAAGGCTTCATCTGGAACTCATATCTTCATGTTCATCAGAGGATCCACACGGGAGAGAAACCCTATAAATGTGGC ATGTGTGGTAAGAGCTTCAGTCAGACTTCACATCTTCAAGCCCATCAGAGAGTCCATACTGGAGAGAAACCATACAAATGTTTTGTGTGT >In-frame_PVR_ENST00000406449_chr19_45150842_+_ZNF233_ENST00000334152_chr19_44768467_+_2124nt ATGGCCCGAGCCATGGCCGCCGCGTGGCCGCTGCTGCTGGTGGCGCTACTGGTGCTGTCCTGGCCACCCCCAGGAACCGGGGACGTCGTC GTGCAGGCGCCCACCCAGGTGCCCGGCTTCTTGGGCGACTCCGTGACGCTGCCCTGCTACCTACAGGTGCCCAACATGGAGGTGACGCAT GTGTCACAGCTGACTTGGGCGCGGCATGGTGAATCTGGCAGCATGGCCGTCTTCCACCAAACGCAGGGCCCCAGCTATTCGGAGTCCAAA CGGCTGGAATTCGTGGCAGCCAGACTGGGCGCGGAGCTGCGGAATGCCTCGCTGAGGATGTTCGGGTTGCGCGTAGAGGATGAAGGCAAC TACACCTGCCTGTTCGTCACGTTCCCGCAGGGCAGCAGGAGCGTGGATATCTGGCTCCGAGTGCTTGTTCTGCCTTCCCAGGACCCTGCC CTTCCCCAGAAGGAGCAGGAGAAAATGACCAAGTTTCAGTTATTGGCCATAAGATTGAGATTACATCTGCTTGATGTTGTAGGAGATGGT GACATTCAAGGATGTGGCTGTGGTCTTCACCAGGGAGGAGCTGGGGTTGCTGGACCTTGCCCAGAGAAAGCTGTACCAAGATGTGATGCT GGAGAACTTCAGGAACCTGCTGTCAGTGGGCTATCAACCCTTCAAACTAGATGTGATATTACAGTTGGGAAAAGAAGACAAGCTTCGGAT GATGGAGACAGAAATCCAAGGAGATGGGTGTTCAGGCAAAGAATTGCTCATCAACATGATGATCATGGAGTACACAAAAGAGAGAAAGCT TTTAGCCACAATAATTGTGGAAAAGACTGTGTGAAGGAATCATCCCAGCATAGCATAATCCAATCAGGAGAGCAAACCTCTGATGAAAAT GGAAAAGGCTTAAGTGTTGGCTCTAATCTTGAACTTCACCAGCAACTACACTTAAGAGACAAGCCTCATGTAAATGTTGAGTACGGGAAG GGCATAGGTTACAGCTCAGGGCTTCCCAGGCATCAGTGTTTCCACATAGGAGAGAAATGCTATAGGAATGGTGACAGTGGTGAGGGCTTC AGTCAGGGCTCACATCTGCAACCTCATCAGAGAGTCAGCACAGGAGAGAACCTCTACAGATGTCAGGTATATGCCCGGAGCTCCAACCAG AACTCCTGTCTTCCCTCTCATGAGCTTACTCACCCAGGAGAGAAGTTGTGTACATGTGGCAGGTGTGGGAAGGGCTTCCATCATAGCTTA GATTTTGACATTCACTGTGTAGACAGTGCTGGAGAGAGAGCCTGTAAATGTGATGTATATGATAAAGGCTTCAGTCAGACATCACAACTT CAAGCCCATCAGAGAGGTCACTCTAGAGACAAGACATACAAATGGGAAGTAAGTGACAGGATATTTAATAGGAATTCTGGTCTTCACCAG AGAGTTCACACTGGAGAGAAACCATATAAATGTGAGGTATGTGATAAGGGCTTCAGTAAGGCCTCAAATCTTCAAGCCCATCAGAGAATC CACACTGGAGAGAAACCCTACAAATGTGATGTGTGTGATAAGAACTTCAGCCGTAATTCCCACCTTCAGGCCCATCAGAGAGTCCATACA GGAGAGAAACCCTACAAATGTGACACATGTGGGAAGGACTTCAGTCAGATCTCTCATCTTCAGGCCCATCAGAGAGTTCACAAAGGAGAG AAGCCATACAAATGTGAGACATGTGGGAAGGGCTTTAGTCAGAGTTCGCATCTCCAAGACCATCAGCAAGTCCATACTGGAGAGAATCCC TACAAATGTGATGTGTGTGGGAAAGGCTTCAGTTGGAGTTCACATCTTCAAGCCCATCAGAGAGTCCACACAGGAGAGAAACCATACAAA TGTGAAGAATGTAGGAAAGGCTTCATCTGGAACTCATATCTTCATGTTCATCAGAGGATCCACACGGGAGAGAAACCCTATAAATGTGGC ATGTGTGGTAAGAGCTTCAGTCAGACTTCACATCTTCAAGCCCATCAGAGAGTCCATACTGGAGAGAAACCATACAAATGTTTTGTGTGT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_PVR_ENST00000425690_chr19_45150842_+_ZNF233_ENST00000334152_chr19_44768467_+_2423nt AGCGGGACTGAGCGCCGGGAGAGACCTGCGCAGGCGCAGGCGCGCGGGAAGGGCCAGCCTGGGTGGCCCACCCCGCGCCTGGCGGGACTG GCCGCCAACTCCCCTCCGCTCCAGTCACTTGTCTGGAGCTTGAAGAAGTGGGTATTCCCCTTCCCACCCCAGGCACTGGAGGAGCGGCCC CCCGGGGATTCCAGGACCTGAGCTCCGGGAGCTGGACTCGCAGCGACCGCGGCAGAGCGAGCGGGCGCCGGGAAGCGAGGAGACGCCCGC GGGAGGCCCAGCTGCTCGGAGCAACTGGCATGGCCCGAGCCATGGCCGCCGCGTGGCCGCTGCTGCTGGTGGCGCTACTGGTGCTGTCCT GGCCACCCCCAGGAACCGGGGACGTCGTCGTGCAGGCGCCCACCCAGGTGCCCGGCTTCTTGGGCGACTCCGTGACGCTGCCCTGCTACC TACAGGTGCCCAACATGGAGGTGACGCATGTGTCACAGCTGACTTGGGCGCGGCATGGTGAATCTGGCAGCATGGCCGTCTTCCACCAAA CGCAGGGCCCCAGCTATTCGGAGTCCAAACGGCTGGAATTCGTGGCAGCCAGACTGGGCGCGGAGCTGCGGAATGCCTCGCTGAGGATGT TCGGGTTGCGCGTAGAGGATGAAGGCAACTACACCTGCCTGTTCGTCACGTTCCCGCAGGGCAGCAGGAGCGTGGATATCTGGCTCCGAG TGCTTGTTCTGCCTTCCCAGGACCCTGCCCTTCCCCAGAAGGAGCAGGAGAAAATGACCAAGTTTCAGTTATTGGCCATAAGATTGAGAT TACATCTGCTTGATGTTGTAGGAGATGGTGACATTCAAGGATGTGGCTGTGGTCTTCACCAGGGAGGAGCTGGGGTTGCTGGACCTTGCC CAGAGAAAGCTGTACCAAGATGTGATGCTGGAGAACTTCAGGAACCTGCTGTCAGTGGGCTATCAACCCTTCAAACTAGATGTGATATTA CAGTTGGGAAAAGAAGACAAGCTTCGGATGATGGAGACAGAAATCCAAGGAGATGGGTGTTCAGGCAAAGAATTGCTCATCAACATGATG ATCATGGAGTACACAAAAGAGAGAAAGCTTTTAGCCACAATAATTGTGGAAAAGACTGTGTGAAGGAATCATCCCAGCATAGCATAATCC AATCAGGAGAGCAAACCTCTGATGAAAATGGAAAAGGCTTAAGTGTTGGCTCTAATCTTGAACTTCACCAGCAACTACACTTAAGAGACA AGCCTCATGTAAATGTTGAGTACGGGAAGGGCATAGGTTACAGCTCAGGGCTTCCCAGGCATCAGTGTTTCCACATAGGAGAGAAATGCT ATAGGAATGGTGACAGTGGTGAGGGCTTCAGTCAGGGCTCACATCTGCAACCTCATCAGAGAGTCAGCACAGGAGAGAACCTCTACAGAT GTCAGGTATATGCCCGGAGCTCCAACCAGAACTCCTGTCTTCCCTCTCATGAGCTTACTCACCCAGGAGAGAAGTTGTGTACATGTGGCA GGTGTGGGAAGGGCTTCCATCATAGCTTAGATTTTGACATTCACTGTGTAGACAGTGCTGGAGAGAGAGCCTGTAAATGTGATGTATATG ATAAAGGCTTCAGTCAGACATCACAACTTCAAGCCCATCAGAGAGGTCACTCTAGAGACAAGACATACAAATGGGAAGTAAGTGACAGGA TATTTAATAGGAATTCTGGTCTTCACCAGAGAGTTCACACTGGAGAGAAACCATATAAATGTGAGGTATGTGATAAGGGCTTCAGTAAGG CCTCAAATCTTCAAGCCCATCAGAGAATCCACACTGGAGAGAAACCCTACAAATGTGATGTGTGTGATAAGAACTTCAGCCGTAATTCCC ACCTTCAGGCCCATCAGAGAGTCCATACAGGAGAGAAACCCTACAAATGTGACACATGTGGGAAGGACTTCAGTCAGATCTCTCATCTTC AGGCCCATCAGAGAGTTCACAAAGGAGAGAAGCCATACAAATGTGAGACATGTGGGAAGGGCTTTAGTCAGAGTTCGCATCTCCAAGACC ATCAGCAAGTCCATACTGGAGAGAATCCCTACAAATGTGATGTGTGTGGGAAAGGCTTCAGTTGGAGTTCACATCTTCAAGCCCATCAGA GAGTCCACACAGGAGAGAAACCATACAAATGTGAAGAATGTAGGAAAGGCTTCATCTGGAACTCATATCTTCATGTTCATCAGAGGATCC ACACGGGAGAGAAACCCTATAAATGTGGCATGTGTGGTAAGAGCTTCAGTCAGACTTCACATCTTCAAGCCCATCAGAGAGTCCATACTG >In-frame_PVR_ENST00000344956_chr19_45150842_+_ZNF233_ENST00000334152_chr19_44768467_+_2423nt AGCGGGACTGAGCGCCGGGAGAGACCTGCGCAGGCGCAGGCGCGCGGGAAGGGCCAGCCTGGGTGGCCCACCCCGCGCCTGGCGGGACTG GCCGCCAACTCCCCTCCGCTCCAGTCACTTGTCTGGAGCTTGAAGAAGTGGGTATTCCCCTTCCCACCCCAGGCACTGGAGGAGCGGCCC CCCGGGGATTCCAGGACCTGAGCTCCGGGAGCTGGACTCGCAGCGACCGCGGCAGAGCGAGCGGGCGCCGGGAAGCGAGGAGACGCCCGC GGGAGGCCCAGCTGCTCGGAGCAACTGGCATGGCCCGAGCCATGGCCGCCGCGTGGCCGCTGCTGCTGGTGGCGCTACTGGTGCTGTCCT GGCCACCCCCAGGAACCGGGGACGTCGTCGTGCAGGCGCCCACCCAGGTGCCCGGCTTCTTGGGCGACTCCGTGACGCTGCCCTGCTACC TACAGGTGCCCAACATGGAGGTGACGCATGTGTCACAGCTGACTTGGGCGCGGCATGGTGAATCTGGCAGCATGGCCGTCTTCCACCAAA CGCAGGGCCCCAGCTATTCGGAGTCCAAACGGCTGGAATTCGTGGCAGCCAGACTGGGCGCGGAGCTGCGGAATGCCTCGCTGAGGATGT TCGGGTTGCGCGTAGAGGATGAAGGCAACTACACCTGCCTGTTCGTCACGTTCCCGCAGGGCAGCAGGAGCGTGGATATCTGGCTCCGAG TGCTTGTTCTGCCTTCCCAGGACCCTGCCCTTCCCCAGAAGGAGCAGGAGAAAATGACCAAGTTTCAGTTATTGGCCATAAGATTGAGAT TACATCTGCTTGATGTTGTAGGAGATGGTGACATTCAAGGATGTGGCTGTGGTCTTCACCAGGGAGGAGCTGGGGTTGCTGGACCTTGCC CAGAGAAAGCTGTACCAAGATGTGATGCTGGAGAACTTCAGGAACCTGCTGTCAGTGGGCTATCAACCCTTCAAACTAGATGTGATATTA CAGTTGGGAAAAGAAGACAAGCTTCGGATGATGGAGACAGAAATCCAAGGAGATGGGTGTTCAGGCAAAGAATTGCTCATCAACATGATG ATCATGGAGTACACAAAAGAGAGAAAGCTTTTAGCCACAATAATTGTGGAAAAGACTGTGTGAAGGAATCATCCCAGCATAGCATAATCC AATCAGGAGAGCAAACCTCTGATGAAAATGGAAAAGGCTTAAGTGTTGGCTCTAATCTTGAACTTCACCAGCAACTACACTTAAGAGACA AGCCTCATGTAAATGTTGAGTACGGGAAGGGCATAGGTTACAGCTCAGGGCTTCCCAGGCATCAGTGTTTCCACATAGGAGAGAAATGCT ATAGGAATGGTGACAGTGGTGAGGGCTTCAGTCAGGGCTCACATCTGCAACCTCATCAGAGAGTCAGCACAGGAGAGAACCTCTACAGAT GTCAGGTATATGCCCGGAGCTCCAACCAGAACTCCTGTCTTCCCTCTCATGAGCTTACTCACCCAGGAGAGAAGTTGTGTACATGTGGCA GGTGTGGGAAGGGCTTCCATCATAGCTTAGATTTTGACATTCACTGTGTAGACAGTGCTGGAGAGAGAGCCTGTAAATGTGATGTATATG ATAAAGGCTTCAGTCAGACATCACAACTTCAAGCCCATCAGAGAGGTCACTCTAGAGACAAGACATACAAATGGGAAGTAAGTGACAGGA TATTTAATAGGAATTCTGGTCTTCACCAGAGAGTTCACACTGGAGAGAAACCATATAAATGTGAGGTATGTGATAAGGGCTTCAGTAAGG CCTCAAATCTTCAAGCCCATCAGAGAATCCACACTGGAGAGAAACCCTACAAATGTGATGTGTGTGATAAGAACTTCAGCCGTAATTCCC ACCTTCAGGCCCATCAGAGAGTCCATACAGGAGAGAAACCCTACAAATGTGACACATGTGGGAAGGACTTCAGTCAGATCTCTCATCTTC AGGCCCATCAGAGAGTTCACAAAGGAGAGAAGCCATACAAATGTGAGACATGTGGGAAGGGCTTTAGTCAGAGTTCGCATCTCCAAGACC ATCAGCAAGTCCATACTGGAGAGAATCCCTACAAATGTGATGTGTGTGGGAAAGGCTTCAGTTGGAGTTCACATCTTCAAGCCCATCAGA GAGTCCACACAGGAGAGAAACCATACAAATGTGAAGAATGTAGGAAAGGCTTCATCTGGAACTCATATCTTCATGTTCATCAGAGGATCC ACACGGGAGAGAAACCCTATAAATGTGGCATGTGTGGTAAGAGCTTCAGTCAGACTTCACATCTTCAAGCCCATCAGAGAGTCCATACTG >In-frame_PVR_ENST00000403059_chr19_45150842_+_ZNF233_ENST00000334152_chr19_44768467_+_2311nt AGTCACTTGTCTGGAGCTTGAAGAAGTGGGTATTCCCCTTCCCACCCCAGGCACTGGAGGAGCGGCCCCCCGGGGATTCCAGGACCTGAG CTCCGGGAGCTGGACTCGCAGCGACCGCGGCAGAGCGAGCGGGCGCCGGGAAGCGAGGAGACGCCCGCGGGAGGCCCAGCTGCTCGGAGC AACTGGCATGGCCCGAGCCATGGCCGCCGCGTGGCCGCTGCTGCTGGTGGCGCTACTGGTGCTGTCCTGGCCACCCCCAGGAACCGGGGA CGTCGTCGTGCAGGCGCCCACCCAGGTGCCCGGCTTCTTGGGCGACTCCGTGACGCTGCCCTGCTACCTACAGGTGCCCAACATGGAGGT GACGCATGTGTCACAGCTGACTTGGGCGCGGCATGGTGAATCTGGCAGCATGGCCGTCTTCCACCAAACGCAGGGCCCCAGCTATTCGGA GTCCAAACGGCTGGAATTCGTGGCAGCCAGACTGGGCGCGGAGCTGCGGAATGCCTCGCTGAGGATGTTCGGGTTGCGCGTAGAGGATGA AGGCAACTACACCTGCCTGTTCGTCACGTTCCCGCAGGGCAGCAGGAGCGTGGATATCTGGCTCCGAGTGCTTGTTCTGCCTTCCCAGGA CCCTGCCCTTCCCCAGAAGGAGCAGGAGAAAATGACCAAGTTTCAGTTATTGGCCATAAGATTGAGATTACATCTGCTTGATGTTGTAGG AGATGGTGACATTCAAGGATGTGGCTGTGGTCTTCACCAGGGAGGAGCTGGGGTTGCTGGACCTTGCCCAGAGAAAGCTGTACCAAGATG TGATGCTGGAGAACTTCAGGAACCTGCTGTCAGTGGGCTATCAACCCTTCAAACTAGATGTGATATTACAGTTGGGAAAAGAAGACAAGC TTCGGATGATGGAGACAGAAATCCAAGGAGATGGGTGTTCAGGCAAAGAATTGCTCATCAACATGATGATCATGGAGTACACAAAAGAGA GAAAGCTTTTAGCCACAATAATTGTGGAAAAGACTGTGTGAAGGAATCATCCCAGCATAGCATAATCCAATCAGGAGAGCAAACCTCTGA TGAAAATGGAAAAGGCTTAAGTGTTGGCTCTAATCTTGAACTTCACCAGCAACTACACTTAAGAGACAAGCCTCATGTAAATGTTGAGTA CGGGAAGGGCATAGGTTACAGCTCAGGGCTTCCCAGGCATCAGTGTTTCCACATAGGAGAGAAATGCTATAGGAATGGTGACAGTGGTGA GGGCTTCAGTCAGGGCTCACATCTGCAACCTCATCAGAGAGTCAGCACAGGAGAGAACCTCTACAGATGTCAGGTATATGCCCGGAGCTC CAACCAGAACTCCTGTCTTCCCTCTCATGAGCTTACTCACCCAGGAGAGAAGTTGTGTACATGTGGCAGGTGTGGGAAGGGCTTCCATCA TAGCTTAGATTTTGACATTCACTGTGTAGACAGTGCTGGAGAGAGAGCCTGTAAATGTGATGTATATGATAAAGGCTTCAGTCAGACATC ACAACTTCAAGCCCATCAGAGAGGTCACTCTAGAGACAAGACATACAAATGGGAAGTAAGTGACAGGATATTTAATAGGAATTCTGGTCT TCACCAGAGAGTTCACACTGGAGAGAAACCATATAAATGTGAGGTATGTGATAAGGGCTTCAGTAAGGCCTCAAATCTTCAAGCCCATCA GAGAATCCACACTGGAGAGAAACCCTACAAATGTGATGTGTGTGATAAGAACTTCAGCCGTAATTCCCACCTTCAGGCCCATCAGAGAGT CCATACAGGAGAGAAACCCTACAAATGTGACACATGTGGGAAGGACTTCAGTCAGATCTCTCATCTTCAGGCCCATCAGAGAGTTCACAA AGGAGAGAAGCCATACAAATGTGAGACATGTGGGAAGGGCTTTAGTCAGAGTTCGCATCTCCAAGACCATCAGCAAGTCCATACTGGAGA GAATCCCTACAAATGTGATGTGTGTGGGAAAGGCTTCAGTTGGAGTTCACATCTTCAAGCCCATCAGAGAGTCCACACAGGAGAGAAACC ATACAAATGTGAAGAATGTAGGAAAGGCTTCATCTGGAACTCATATCTTCATGTTCATCAGAGGATCCACACGGGAGAGAAACCCTATAA ATGTGGCATGTGTGGTAAGAGCTTCAGTCAGACTTCACATCTTCAAGCCCATCAGAGAGTCCATACTGGAGAGAAACCATACAAATGTTT >In-frame_PVR_ENST00000406449_chr19_45150842_+_ZNF233_ENST00000334152_chr19_44768467_+_2124nt ATGGCCCGAGCCATGGCCGCCGCGTGGCCGCTGCTGCTGGTGGCGCTACTGGTGCTGTCCTGGCCACCCCCAGGAACCGGGGACGTCGTC GTGCAGGCGCCCACCCAGGTGCCCGGCTTCTTGGGCGACTCCGTGACGCTGCCCTGCTACCTACAGGTGCCCAACATGGAGGTGACGCAT GTGTCACAGCTGACTTGGGCGCGGCATGGTGAATCTGGCAGCATGGCCGTCTTCCACCAAACGCAGGGCCCCAGCTATTCGGAGTCCAAA CGGCTGGAATTCGTGGCAGCCAGACTGGGCGCGGAGCTGCGGAATGCCTCGCTGAGGATGTTCGGGTTGCGCGTAGAGGATGAAGGCAAC TACACCTGCCTGTTCGTCACGTTCCCGCAGGGCAGCAGGAGCGTGGATATCTGGCTCCGAGTGCTTGTTCTGCCTTCCCAGGACCCTGCC CTTCCCCAGAAGGAGCAGGAGAAAATGACCAAGTTTCAGTTATTGGCCATAAGATTGAGATTACATCTGCTTGATGTTGTAGGAGATGGT GACATTCAAGGATGTGGCTGTGGTCTTCACCAGGGAGGAGCTGGGGTTGCTGGACCTTGCCCAGAGAAAGCTGTACCAAGATGTGATGCT GGAGAACTTCAGGAACCTGCTGTCAGTGGGCTATCAACCCTTCAAACTAGATGTGATATTACAGTTGGGAAAAGAAGACAAGCTTCGGAT GATGGAGACAGAAATCCAAGGAGATGGGTGTTCAGGCAAAGAATTGCTCATCAACATGATGATCATGGAGTACACAAAAGAGAGAAAGCT TTTAGCCACAATAATTGTGGAAAAGACTGTGTGAAGGAATCATCCCAGCATAGCATAATCCAATCAGGAGAGCAAACCTCTGATGAAAAT GGAAAAGGCTTAAGTGTTGGCTCTAATCTTGAACTTCACCAGCAACTACACTTAAGAGACAAGCCTCATGTAAATGTTGAGTACGGGAAG GGCATAGGTTACAGCTCAGGGCTTCCCAGGCATCAGTGTTTCCACATAGGAGAGAAATGCTATAGGAATGGTGACAGTGGTGAGGGCTTC AGTCAGGGCTCACATCTGCAACCTCATCAGAGAGTCAGCACAGGAGAGAACCTCTACAGATGTCAGGTATATGCCCGGAGCTCCAACCAG AACTCCTGTCTTCCCTCTCATGAGCTTACTCACCCAGGAGAGAAGTTGTGTACATGTGGCAGGTGTGGGAAGGGCTTCCATCATAGCTTA GATTTTGACATTCACTGTGTAGACAGTGCTGGAGAGAGAGCCTGTAAATGTGATGTATATGATAAAGGCTTCAGTCAGACATCACAACTT CAAGCCCATCAGAGAGGTCACTCTAGAGACAAGACATACAAATGGGAAGTAAGTGACAGGATATTTAATAGGAATTCTGGTCTTCACCAG AGAGTTCACACTGGAGAGAAACCATATAAATGTGAGGTATGTGATAAGGGCTTCAGTAAGGCCTCAAATCTTCAAGCCCATCAGAGAATC CACACTGGAGAGAAACCCTACAAATGTGATGTGTGTGATAAGAACTTCAGCCGTAATTCCCACCTTCAGGCCCATCAGAGAGTCCATACA GGAGAGAAACCCTACAAATGTGACACATGTGGGAAGGACTTCAGTCAGATCTCTCATCTTCAGGCCCATCAGAGAGTTCACAAAGGAGAG AAGCCATACAAATGTGAGACATGTGGGAAGGGCTTTAGTCAGAGTTCGCATCTCCAAGACCATCAGCAAGTCCATACTGGAGAGAATCCC TACAAATGTGATGTGTGTGGGAAAGGCTTCAGTTGGAGTTCACATCTTCAAGCCCATCAGAGAGTCCACACAGGAGAGAAACCATACAAA TGTGAAGAATGTAGGAAAGGCTTCATCTGGAACTCATATCTTCATGTTCATCAGAGGATCCACACGGGAGAGAAACCCTATAAATGTGGC ATGTGTGGTAAGAGCTTCAGTCAGACTTCACATCTTCAAGCCCATCAGAGAGTCCATACTGGAGAGAAACCATACAAATGTTTTGTGTGT |
Top |
FusionGenePPI for PVR_ZNF233 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| PVR | CD226, PVRL3, DYNLT1, AP1M2, VTN, ELAVL1, ZC3HAV1, TIGIT, PLA2G3, WNK1, SLC30A2, KRTAP10-7, KRTAP10-9, KRTAP10-8, KRTAP10-3, NOTCH2NL, CD96, NLRX1, C4A, UBE2C, RYK, CDON, PI4K2A, RAB5B, LRBA, FBXL20, GNPAT, MMS22L, MTCH2, XPO6, QSOX1, ATR, FAM20B, GPD2, PPM1B, LANCL2, ALG5, USP30, ARV1, GNA13, CISD2, METAP2, XPO5, TNFSF9, HELLS, ALG11, ULBP3, STAT3, RFC3, EFNB1, FAM134A, TRIM25 | ZNF233 | CACNA1A |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for PVR_ZNF233 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for PVR_ZNF233 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | PVR | C0032371 | Poliomyelitis | 1 | CTD_human |
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