|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 29611 |
FusionGeneSummary for PTPRZ1_DOCK4 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PTPRZ1_DOCK4 | Fusion gene ID: 29611 | Hgene | Tgene | Gene symbol | PTPRZ1 | DOCK4 | Gene ID | 5803 | 9732 |
| Gene name | protein tyrosine phosphatase, receptor type Z1 | dedicator of cytokinesis 4 | |
| Synonyms | HPTPZ|HPTPzeta|PTP-ZETA|PTP18|PTPRZ|PTPZ|R-PTP-zeta-2|RPTPB|RPTPbeta|phosphacan | - | |
| Cytomap | 7q31.32 | 7q31.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | receptor-type tyrosine-protein phosphatase zetaprotein tyrosine phosphatase, receptor-type, Z polypeptide 1protein tyrosine phosphatase, receptor-type, zeta polypeptide 1protein-tyrosine phosphatase receptor type Z polypeptide 2receptor-type tyrosine | dedicator of cytokinesis protein 4 | |
| Modification date | 20180519 | 20180525 | |
| UniProtAcc | P23471 | Q8N1I0 | |
| Ensembl transtripts involved in fusion gene | ENST00000393386, ENST00000449182, ENST00000483028, | ENST00000428084, ENST00000494651, ENST00000437633, ENST00000476846, | |
| Fusion gene scores | * DoF score | 12 X 12 X 7=1008 | 4 X 5 X 6=120 |
| # samples | 16 | 6 | |
| ** MAII score | log2(16/1008*10)=-2.65535182861255 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(6/120*10)=-1 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: PTPRZ1 [Title/Abstract] AND DOCK4 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Oncogene involved fusion gene, in-frame and retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | SKCM | TCGA-EE-A20I-06A | PTPRZ1 | chr7 | 121624171 | + | DOCK4 | chr7 | 111644186 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000393386 | ENST00000428084 | PTPRZ1 | chr7 | 121624171 | + | DOCK4 | chr7 | 111644186 | - |
| 5CDS-intron | ENST00000393386 | ENST00000494651 | PTPRZ1 | chr7 | 121624171 | + | DOCK4 | chr7 | 111644186 | - |
| 5CDS-intron | ENST00000393386 | ENST00000437633 | PTPRZ1 | chr7 | 121624171 | + | DOCK4 | chr7 | 111644186 | - |
| 5CDS-5UTR | ENST00000393386 | ENST00000476846 | PTPRZ1 | chr7 | 121624171 | + | DOCK4 | chr7 | 111644186 | - |
| In-frame | ENST00000449182 | ENST00000428084 | PTPRZ1 | chr7 | 121624171 | + | DOCK4 | chr7 | 111644186 | - |
| 5CDS-intron | ENST00000449182 | ENST00000494651 | PTPRZ1 | chr7 | 121624171 | + | DOCK4 | chr7 | 111644186 | - |
| 5CDS-intron | ENST00000449182 | ENST00000437633 | PTPRZ1 | chr7 | 121624171 | + | DOCK4 | chr7 | 111644186 | - |
| 5CDS-5UTR | ENST00000449182 | ENST00000476846 | PTPRZ1 | chr7 | 121624171 | + | DOCK4 | chr7 | 111644186 | - |
| intron-3CDS | ENST00000483028 | ENST00000428084 | PTPRZ1 | chr7 | 121624171 | + | DOCK4 | chr7 | 111644186 | - |
| intron-intron | ENST00000483028 | ENST00000494651 | PTPRZ1 | chr7 | 121624171 | + | DOCK4 | chr7 | 111644186 | - |
| intron-intron | ENST00000483028 | ENST00000437633 | PTPRZ1 | chr7 | 121624171 | + | DOCK4 | chr7 | 111644186 | - |
| intron-5UTR | ENST00000483028 | ENST00000476846 | PTPRZ1 | chr7 | 121624171 | + | DOCK4 | chr7 | 111644186 | - |
Top |
FusionProtFeatures for PTPRZ1_DOCK4 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| PTPRZ1 | DOCK4 |
| Protein tyrosine phosphatase that negatively regulatesoligodendrocyte precursor proliferation in the embryonic spinalcord. Required for normal differentiation of the precursor cellsinto mature, fully myelinating oligodendrocytes. May play a rolein protecting oligondendrocytes against apoptosis. May play a rolein the establishment of contextual memory, probably via thedephosphorylation of proteins that are part of important signalingcascades (By similarity). {ECO:0000250}. | Involved in regulation of adherens junction betweencells. Plays a role in cell migration. Functions as a guaninenucleotide exchange factor (GEF), which activates Rap1 smallGTPase by exchanging bound GDP for free GTP.{ECO:0000269|PubMed:12628187, ECO:0000269|PubMed:20679435}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | PTPRZ1 | chr7:121624171 | chr7:111644186 | ENST00000393386 | + | 8 | 30 | 36_300 | 309 | 2316 | Domain | Alpha-carbonic anhydrase |
| Tgene | >DOCK4 | chr7:121624171 | chr7:111644186 | ENST00000428084 | - | 0 | 53 | 1642_1863 | 12 | 1976 | Compositional bias | Note=Ser-rich |
| Tgene | >DOCK4 | chr7:121624171 | chr7:111644186 | ENST00000428084 | - | 0 | 53 | 1875_1960 | 12 | 1976 | Compositional bias | Note=Pro-rich |
| Tgene | >DOCK4 | chr7:121624171 | chr7:111644186 | ENST00000437633 | - | 0 | 52 | 1642_1863 | 12 | 1967 | Compositional bias | Note=Ser-rich |
| Tgene | >DOCK4 | chr7:121624171 | chr7:111644186 | ENST00000437633 | - | 0 | 52 | 1875_1960 | 12 | 1967 | Compositional bias | Note=Pro-rich |
| Tgene | >DOCK4 | chr7:121624171 | chr7:111644186 | ENST00000428084 | - | 0 | 53 | 1190_1596 | 12 | 1976 | Domain | DHR-2 |
| Tgene | >DOCK4 | chr7:121624171 | chr7:111644186 | ENST00000428084 | - | 0 | 53 | 401_574 | 12 | 1976 | Domain | DHR-1 |
| Tgene | >DOCK4 | chr7:121624171 | chr7:111644186 | ENST00000437633 | - | 0 | 52 | 1190_1596 | 12 | 1967 | Domain | DHR-2 |
| Tgene | >DOCK4 | chr7:121624171 | chr7:111644186 | ENST00000437633 | - | 0 | 52 | 401_574 | 12 | 1967 | Domain | DHR-1 |
| Tgene | >DOCK4 | chr7:121624171 | chr7:111644186 | ENST00000428084 | - | 0 | 53 | 1788_1794 | 12 | 1976 | Motif | SH3-binding |
| Tgene | >DOCK4 | chr7:121624171 | chr7:111644186 | ENST00000437633 | - | 0 | 52 | 1788_1794 | 12 | 1967 | Motif | SH3-binding |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >PTPRZ1 | chr7:121624171 | chr7:111644186 | ENST00000393386 | + | 8 | 30 | 1717_1992 | 309 | 2316 | Domain | Tyrosine-protein phosphatase 1 |
| Hgene | >PTPRZ1 | chr7:121624171 | chr7:111644186 | ENST00000393386 | + | 8 | 30 | 2023_2282 | 309 | 2316 | Domain | Tyrosine-protein phosphatase 2 |
| Hgene | >PTPRZ1 | chr7:121624171 | chr7:111644186 | ENST00000393386 | + | 8 | 30 | 314_413 | 309 | 2316 | Domain | Fibronectin type-III |
| Hgene | >PTPRZ1 | chr7:121624171 | chr7:111644186 | ENST00000393386 | + | 8 | 30 | 1933_1939 | 309 | 2316 | Region | Substrate binding |
| Hgene | >PTPRZ1 | chr7:121624171 | chr7:111644186 | ENST00000393386 | + | 8 | 30 | 1663_2315 | 309 | 2316 | Topological domain | Cytoplasmic |
| Hgene | >PTPRZ1 | chr7:121624171 | chr7:111644186 | ENST00000393386 | + | 8 | 30 | 25_1636 | 309 | 2316 | Topological domain | Extracellular |
| Hgene | >PTPRZ1 | chr7:121624171 | chr7:111644186 | ENST00000393386 | + | 8 | 30 | 1637_1662 | 309 | 2316 | Transmembrane | Helical |
| Tgene | DOCK4 | chr7:121624171 | chr7:111644186 | ENST00000428084 | - | 0 | 53 | 6_67 | 12 | 1976 | Domain | SH3 |
| Tgene | DOCK4 | chr7:121624171 | chr7:111644186 | ENST00000437633 | - | 0 | 52 | 6_67 | 12 | 1967 | Domain | SH3 |
Top |
FusionGeneSequence for PTPRZ1_DOCK4 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_PTPRZ1_ENST00000393386_chr7_121624171_+_DOCK4_ENST00000428084_chr7_111644186_-_2273aa MRILKRFLACIQLLCVCRLDWANGYYRQQRKLVEEIGWSYTGALNQKNWGKKYPTCNSPKQSPINIDEDLTQVNVNLKKLKFQGWDKTSL ENTFIHNTGKTVEINLTNDYRVSGGVSEMVFKASKITFHWGKCNMSSDGSEHSLEGQKFPLEMQIYCFDADRFSSFEEAVKGKGKLRALS ILFEVGTEENLDFKAIIDGVESVSRFGKQAALDPFILLNLLPNSTDKYYIYNGSLTSPPCTDTVDWIVFKDTVSISESQLAVFCEVLTMQ QSGYVMLMDYLQNNFREQQYKFSRQVFSSYTGKEEIHEAVIASFRGTVPYGLSLEIGDTVQILEKCDGWYRGFALKNPNIKGIFPSSYVH LKNACVKNKGQFEMVIPTEDSVITEMTSTLRDWGTMWKQLYVRNEGDLFHRLWHIMNEILDLRRQVLVGHLTHDRMKDVKRHITARLDWG NEQLGLDLVPRKEYAMVDPEDISITELYRLMEHRHRKKDTPVQASSHHLFVQMKSLMCSNLGEELEVIFSLFDSKENRPISERFFLRLNR NGLPKAPDKPERHCSLFVDLGSSELRKDIYITVHIIRIGRMGAGEKKNACSVQYRRPFGCAVLSIADLLTGETKDDLILKVYMCNTESEW YQIHENIIKKLNARYNLTGSNAGLAVSLQLLHGDIEQIRREYSSVFSHGVSITRKLGFSNIIMPGEMRNDLYITIERGEFEKGGKSVARN VEVTMFIVDSSGQTLKDFISFGSGEPPASEYHSFVLYHNNSPRWSELLKLPIPVDKFRGAHIRFEFRHCSTKEKGEKKLFGFSFVPLMQE DGRTLPDGTHELIVHKCEENTNLQDTTRYLKLPFSKGIFLGNNNQAMKATKESFCITSFLCSTKLTQNGDMLDLLKWRTHPDKITGCLSK LKEIDGSEIVKFLQDTLDTLFGILDENSQKYGSKVFDSLVHIINLLQDSKFHHFKPVMDTYIESHFAGALAYRDLIKVLKWYVDRITEAE RQEHIQEVLKAQEYIFKYIVQSRRLFSLATGGQNEEEFRCCIQELLMSVRFFLSQESKGSGALSQSQAVFLSSFPAVYSELLKLFDVREV ANLVQDTLGSLPTILHVDDSLQAIKLQCIGKTVESQLYTNPDSRYILLPVVLHHLHIHLQEQKDLIMCARILSNVFCLIKKNSSEKSVLE EIDVIVASLLDILLRTILEITSRPQPSSSAMRFQFQDVTGEFVACLLSLLRQMTDRHYQQLLDSFNTKEELRDFLLQIFTVFRILIRPEM FPKDWTVMRLVANNVIITTVLYLSDALRKNFLNENFDYKIWDSYFYLAVIFINQLCLQLEMFTPSKKKKVLEKYGDMRVTMGCEIFSMWQ NLGEHKLHFIPALIGPFLEVTLIPQPDLRNVMIPIFHDMMDWEQRRSGNFKQVEAKLIDKLDSLMSEGKGDETYRELFNSIIPLFGPYPS LLKKIERETWRESGVSLIATVTRLMERLLDYRDCMKMGEVDGKKIGCTVSLLNFYKTELNKEEMYIRYIHKLYDLHLKAQNFTEAAYTLL LYDELLEWSDRPLREFLTYPMQTEWQRKEHLHLTIIQNFDRGKCWENGIILCRKIAEQYESYYDYRNLSKMRMMEASLYDKIMDQQRLEP EFFRVGFYGKKFPFFLRNKEFVCRGHDYERLEAFQQRMLNEFPHAIAMQHANQPDETIFQAEAQYLQIYAVTPIPESQEVLQREGVPDNI KSFYKVNHIWKFRYDRPFHKGTKDKENEFKSLWVERTSLYLVQSLPGISRWFEVEKREVVEMSPLENAIEVLENKNQQLKTLISQCQTRQ MQNINPLTMCLNGVIDAAVNGGVSRYQEAFFVKEYILSHPEDGEKIARLRELMLEQAQILEFGLAVHEKFVPQDMRPLHKKLVDQFFVMK SSLGIQEFSACMQASPVHFPNGSPRVCRNSAPASVSPDGTRVIPRRSPLSYPAVNRYSSSSLSSQASAEVSNITGQSESSDEVFNMQPSP STSSLSSTHSASPNVTSSAPSSARASPLLSDKHKHSRENSCLSPRERPCSAIYPTPVEPSQRMLFNHIGDGALPRSDPNLSAPEKAVNPT PSSWSLDSGKEAKNMSDSGKLISPPVPPRPTQTASPARHTTSVSPSPAGRSPLKGSVQSFTPSPVEYHSPGLISNSPVLSGSYSSGISSL SRCSTSETSGFENQVNEQSAPLPVPVPVPVPSYGGEEPVRKESKTPPPYSVYERTLRRPVPLPHSLSIPVTSEPPALPPKPLAARSSHLE >In-frame_PTPRZ1_ENST00000449182_chr7_121624171_+_DOCK4_ENST00000428084_chr7_111644186_-_2273aa MRILKRFLACIQLLCVCRLDWANGYYRQQRKLVEEIGWSYTGALNQKNWGKKYPTCNSPKQSPINIDEDLTQVNVNLKKLKFQGWDKTSL ENTFIHNTGKTVEINLTNDYRVSGGVSEMVFKASKITFHWGKCNMSSDGSEHSLEGQKFPLEMQIYCFDADRFSSFEEAVKGKGKLRALS ILFEVGTEENLDFKAIIDGVESVSRFGKQAALDPFILLNLLPNSTDKYYIYNGSLTSPPCTDTVDWIVFKDTVSISESQLAVFCEVLTMQ QSGYVMLMDYLQNNFREQQYKFSRQVFSSYTGKEEIHEAVIASFRGTVPYGLSLEIGDTVQILEKCDGWYRGFALKNPNIKGIFPSSYVH LKNACVKNKGQFEMVIPTEDSVITEMTSTLRDWGTMWKQLYVRNEGDLFHRLWHIMNEILDLRRQVLVGHLTHDRMKDVKRHITARLDWG NEQLGLDLVPRKEYAMVDPEDISITELYRLMEHRHRKKDTPVQASSHHLFVQMKSLMCSNLGEELEVIFSLFDSKENRPISERFFLRLNR NGLPKAPDKPERHCSLFVDLGSSELRKDIYITVHIIRIGRMGAGEKKNACSVQYRRPFGCAVLSIADLLTGETKDDLILKVYMCNTESEW YQIHENIIKKLNARYNLTGSNAGLAVSLQLLHGDIEQIRREYSSVFSHGVSITRKLGFSNIIMPGEMRNDLYITIERGEFEKGGKSVARN VEVTMFIVDSSGQTLKDFISFGSGEPPASEYHSFVLYHNNSPRWSELLKLPIPVDKFRGAHIRFEFRHCSTKEKGEKKLFGFSFVPLMQE DGRTLPDGTHELIVHKCEENTNLQDTTRYLKLPFSKGIFLGNNNQAMKATKESFCITSFLCSTKLTQNGDMLDLLKWRTHPDKITGCLSK LKEIDGSEIVKFLQDTLDTLFGILDENSQKYGSKVFDSLVHIINLLQDSKFHHFKPVMDTYIESHFAGALAYRDLIKVLKWYVDRITEAE RQEHIQEVLKAQEYIFKYIVQSRRLFSLATGGQNEEEFRCCIQELLMSVRFFLSQESKGSGALSQSQAVFLSSFPAVYSELLKLFDVREV ANLVQDTLGSLPTILHVDDSLQAIKLQCIGKTVESQLYTNPDSRYILLPVVLHHLHIHLQEQKDLIMCARILSNVFCLIKKNSSEKSVLE EIDVIVASLLDILLRTILEITSRPQPSSSAMRFQFQDVTGEFVACLLSLLRQMTDRHYQQLLDSFNTKEELRDFLLQIFTVFRILIRPEM FPKDWTVMRLVANNVIITTVLYLSDALRKNFLNENFDYKIWDSYFYLAVIFINQLCLQLEMFTPSKKKKVLEKYGDMRVTMGCEIFSMWQ NLGEHKLHFIPALIGPFLEVTLIPQPDLRNVMIPIFHDMMDWEQRRSGNFKQVEAKLIDKLDSLMSEGKGDETYRELFNSIIPLFGPYPS LLKKIERETWRESGVSLIATVTRLMERLLDYRDCMKMGEVDGKKIGCTVSLLNFYKTELNKEEMYIRYIHKLYDLHLKAQNFTEAAYTLL LYDELLEWSDRPLREFLTYPMQTEWQRKEHLHLTIIQNFDRGKCWENGIILCRKIAEQYESYYDYRNLSKMRMMEASLYDKIMDQQRLEP EFFRVGFYGKKFPFFLRNKEFVCRGHDYERLEAFQQRMLNEFPHAIAMQHANQPDETIFQAEAQYLQIYAVTPIPESQEVLQREGVPDNI KSFYKVNHIWKFRYDRPFHKGTKDKENEFKSLWVERTSLYLVQSLPGISRWFEVEKREVVEMSPLENAIEVLENKNQQLKTLISQCQTRQ MQNINPLTMCLNGVIDAAVNGGVSRYQEAFFVKEYILSHPEDGEKIARLRELMLEQAQILEFGLAVHEKFVPQDMRPLHKKLVDQFFVMK SSLGIQEFSACMQASPVHFPNGSPRVCRNSAPASVSPDGTRVIPRRSPLSYPAVNRYSSSSLSSQASAEVSNITGQSESSDEVFNMQPSP STSSLSSTHSASPNVTSSAPSSARASPLLSDKHKHSRENSCLSPRERPCSAIYPTPVEPSQRMLFNHIGDGALPRSDPNLSAPEKAVNPT PSSWSLDSGKEAKNMSDSGKLISPPVPPRPTQTASPARHTTSVSPSPAGRSPLKGSVQSFTPSPVEYHSPGLISNSPVLSGSYSSGISSL SRCSTSETSGFENQVNEQSAPLPVPVPVPVPSYGGEEPVRKESKTPPPYSVYERTLRRPVPLPHSLSIPVTSEPPALPPKPLAARSSHLE |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_PTPRZ1_ENST00000393386_chr7_121624171_+_DOCK4_ENST00000428084_chr7_111644186_-_6819nt ATGCGAATCCTAAAGCGTTTCCTCGCTTGCATTCAGCTCCTCTGTGTTTGCCGCCTGGATTGGGCTAATGGATACTACAGACAACAGAGA AAACTTGTTGAAGAGATTGGCTGGTCCTATACAGGAGCACTGAATCAAAAAAATTGGGGAAAGAAATATCCAACATGTAATAGCCCAAAA CAATCTCCTATCAATATTGATGAAGATCTTACACAAGTAAATGTGAATCTTAAGAAACTTAAATTTCAGGGTTGGGATAAAACATCATTG GAAAACACATTCATTCATAACACTGGGAAAACAGTGGAAATTAATCTCACTAATGACTACCGTGTCAGCGGAGGAGTTTCAGAAATGGTG TTTAAAGCAAGCAAGATAACTTTTCACTGGGGAAAATGCAATATGTCATCTGATGGATCAGAGCATAGTTTAGAAGGACAAAAATTTCCA CTTGAGATGCAAATCTACTGCTTTGATGCGGACCGATTTTCAAGTTTTGAGGAAGCAGTCAAAGGAAAAGGGAAGTTAAGAGCTTTATCC ATTTTGTTTGAGGTTGGGACAGAAGAAAATTTGGATTTCAAAGCGATTATTGATGGAGTCGAAAGTGTTAGTCGTTTTGGGAAGCAGGCT GCTTTAGATCCATTCATACTGTTGAACCTTCTGCCAAACTCAACTGACAAGTATTACATTTACAATGGCTCATTGACATCTCCTCCCTGC ACAGACACAGTTGACTGGATTGTTTTTAAAGATACAGTTAGCATCTCTGAAAGCCAGTTGGCTGTTTTTTGTGAAGTTCTTACAATGCAA CAATCTGGTTATGTCATGCTGATGGACTACTTACAAAACAATTTTCGAGAGCAACAGTACAAGTTCTCTAGACAGGTGTTTTCCTCATAC ACTGGAAAGGAAGAGATTCATGAAGCAGTTATTGCCAGTTTCCGAGGAACCGTTCCATATGGCCTGTCATTGGAAATTGGAGATACAGTT CAGATCCTGGAGAAGTGTGATGGCTGGTACAGAGGATTTGCCTTAAAAAACCCAAATATCAAGGGTATATTTCCTTCCAGCTACGTTCAC TTGAAAAATGCCTGTGTAAAGAACAAAGGACAATTTGAAATGGTTATTCCCACTGAAGACTCTGTTATCACAGAAATGACATCAACATTA AGAGACTGGGGAACCATGTGGAAACAACTCTATGTGCGTAATGAAGGCGATCTCTTCCACCGGCTGTGGCACATCATGAATGAAATCCTG GACCTGAGGCGGCAGGTGCTGGTGGGCCACCTCACCCACGACCGGATGAAGGACGTGAAGCGCCACATTACTGCCCGGCTTGACTGGGGC AATGAACAACTGGGACTGGACCTGGTGCCTAGGAAAGAGTACGCAATGGTGGATCCGGAAGACATCAGCATTACTGAGCTCTACCGATTG ATGGAACATCGACATCGGAAGAAAGACACCCCGGTGCAGGCCAGCAGTCACCACCTCTTTGTCCAGATGAAGAGCCTCATGTGTTCCAAC CTGGGAGAGGAGCTGGAGGTCATCTTCTCACTCTTTGACAGTAAAGAGAACCGGCCAATCAGTGAGAGATTTTTCTTGAGGCTGAATAGA AACGGGCTTCCCAAAGCCCCTGATAAACCGGAACGACATTGCTCCCTCTTTGTGGATTTGGGCAGCAGTGAGCTAAGAAAGGACATTTAT ATCACCGTGCACATTATCCGAATCGGTCGAATGGGAGCAGGAGAAAAAAAGAATGCCTGTAGTGTCCAGTACCGACGACCCTTTGGCTGT GCAGTTCTTAGCATCGCTGACCTGCTAACAGGAGAGACAAAGGATGACCTCATTCTGAAAGTATACATGTGTAACACAGAGAGTGAGTGG TACCAAATCCATGAGAACATCATCAAAAAGCTGAATGCACGTTATAACTTGACTGGCTCCAATGCAGGTTTAGCAGTTTCCTTACAGCTA TTGCACGGAGACATTGAACAAATCAGAAGGGAATATTCATCAGTATTTTCTCATGGAGTATCCATAACAAGGAAGCTGGGATTTTCAAAT ATTATTATGCCTGGTGAAATGAGGAATGATTTATATATCACTATTGAAAGGGGAGAATTTGAGAAAGGAGGGAAGAGCGTGGCCAGAAAT GTGGAAGTTACGATGTTCATTGTAGACAGTAGTGGCCAAACCCTGAAGGATTTTATCTCCTTCGGCTCTGGGGAGCCACCAGCCAGTGAG TACCACTCCTTTGTGCTTTACCATAACAACAGTCCCAGGTGGTCTGAACTGCTGAAACTTCCCATTCCTGTGGATAAATTCCGGGGTGCA CACATCCGCTTCGAGTTTCGGCATTGTTCCACAAAGGAGAAAGGAGAGAAGAAGTTGTTTGGGTTTTCTTTTGTCCCTCTGATGCAAGAA GATGGTAGGACTCTTCCAGATGGCACTCATGAGCTCATCGTGCATAAGTGTGAAGAAAACACAAATCTTCAGGATACTACCCGCTACCTC AAACTTCCCTTTTCCAAGGGCATTTTCCTTGGGAATAATAATCAAGCCATGAAGGCCACAAAGGAGTCCTTTTGTATTACATCTTTTCTC TGTTCCACAAAACTCACACAAAATGGTGATATGCTTGATCTTTTGAAATGGAGAACCCACCCAGACAAGATCACTGGCTGTCTCTCTAAA TTAAAAGAAATTGATGGCTCAGAGATAGTAAAGTTTCTGCAGGATACACTGGATACCTTATTTGGAATTTTAGATGAAAATTCCCAAAAA TATGGGTCTAAAGTGTTTGATTCTTTGGTTCACATAATAAATTTGCTGCAAGATAGCAAATTTCATCATTTTAAACCTGTAATGGACACT TACATTGAGAGTCATTTTGCTGGGGCACTTGCATACAGAGATCTCATCAAAGTGCTCAAATGGTACGTGGACCGGATCACAGAAGCAGAG CGGCAAGAGCATATCCAGGAGGTGCTGAAGGCACAAGAATACATTTTTAAGTATATAGTTCAATCTCGAAGGCTGTTTTCCCTTGCCACT GGTGGGCAAAACGAAGAGGAGTTCCGCTGCTGCATTCAGGAGCTTCTCATGTCAGTCCGTTTCTTTCTTTCGCAAGAGAGCAAAGGGTCT GGAGCATTATCTCAGTCACAGGCTGTGTTTCTGAGCTCTTTCCCTGCCGTGTACTCAGAACTGTTGAAGCTCTTTGATGTCCGGGAAGTA GCCAACTTGGTCCAGGACACCCTGGGCAGTCTGCCGACCATCCTGCATGTGGATGATTCCCTGCAGGCCATCAAACTGCAGTGCATTGGC AAAACCGTGGAAAGCCAGCTTTATACCAACCCAGATTCCCGATACATTCTTCTGCCTGTCGTGTTACATCACCTCCACATTCACTTGCAA GAACAGAAGGACCTGATCATGTGTGCACGTATCCTTAGCAACGTATTTTGTCTTATCAAGAAAAATAGCTCAGAAAAATCTGTGCTGGAG GAAATAGATGTGATAGTGGCCAGCTTGCTGGATATTCTGCTGAGGACCATATTGGAGATCACCAGCCGACCTCAGCCATCCAGCTCAGCA ATGCGGTTCCAGTTCCAGGATGTCACTGGGGAGTTTGTTGCTTGTCTCCTGTCCCTATTACGACAAATGACAGATAGACATTATCAACAG CTTCTTGATAGTTTTAATACAAAGGAAGAACTAAGGGATTTCCTGCTGCAGATATTTACTGTGTTCCGAATATTGATACGCCCGGAGATG TTTCCAAAGGACTGGACTGTTATGCGCTTGGTTGCTAACAATGTTATTATTACAACAGTTCTATACCTCTCAGATGCACTTCGTAAGAAC TTCTTAAATGAAAACTTTGATTATAAGATCTGGGATTCCTACTTTTACCTCGCAGTCATTTTTATAAACCAGTTGTGTCTGCAGTTGGAG ATGTTCACACCTTCCAAGAAGAAAAAGGTGTTAGAAAAGTATGGTGACATGCGGGTAACAATGGGTTGTGAAATTTTCAGCATGTGGCAA AACCTAGGAGAGCACAAGCTTCATTTTATCCCTGCCCTGATTGGCCCCTTCCTAGAAGTGACCTTGATACCCCAGCCAGATCTTCGGAAT GTCATGATTCCAATTTTTCATGATATGATGGACTGGGAGCAGAGGCGGAGTGGCAACTTTAAACAGGTGGAAGCCAAGCTAATTGACAAA CTGGATAGCCTGATGTCAGAAGGCAAAGGTGACGAAACATACCGCGAGCTCTTCAACAGTATAATTCCACTATTTGGTCCCTATCCTAGT CTACTAAAGAAAATTGAGCGGGAAACATGGCGGGAAAGTGGCGTTTCATTAATTGCTACTGTAACTCGTCTAATGGAGAGGTTGTTAGAT TACAGGGACTGCATGAAAATGGGAGAGGTAGATGGCAAAAAGATTGGCTGCACAGTTAGCCTTCTGAACTTCTATAAGACTGAACTGAAC AAGGAGGAGATGTATATACGCTACATTCACAAACTCTATGATCTGCATCTCAAAGCACAGAACTTTACAGAAGCTGCATATACCCTCCTC TTATATGACGAGCTACTGGAATGGTCTGATCGGCCCCTCAGGGAGTTCCTGACCTACCCCATGCAAACAGAATGGCAGCGCAAAGAGCAC CTGCACCTCACCATCATCCAGAACTTTGACAGAGGCAAATGTTGGGAGAATGGCATTATCTTGTGCCGGAAGATTGCAGAGCAGTATGAG AGTTATTATGACTACAGAAACCTGAGCAAGATGCGGATGATGGAAGCCTCTTTGTATGACAAAATTATGGACCAGCAACGTCTTGAACCA GAGTTCTTCAGAGTTGGATTTTATGGAAAAAAATTTCCATTTTTCTTAAGAAATAAGGAGTTTGTGTGTCGAGGGCATGACTACGAGAGG CTGGAAGCCTTCCAACAGAGAATGCTGAACGAGTTCCCCCATGCCATCGCCATGCAGCACGCCAACCAGCCCGATGAGACCATCTTCCAG GCAGAAGCTCAGTATTTGCAGATATATGCTGTGACTCCCATTCCAGAGAGCCAGGAGGTCCTGCAGAGAGAGGGTGTTCCGGACAACATC AAAAGCTTCTATAAAGTGAATCACATCTGGAAATTCCGCTATGACCGACCATTTCACAAAGGCACAAAAGATAAAGAGAATGAATTCAAG AGTCTCTGGGTGGAGAGAACGTCATTATACTTGGTGCAGAGTTTGCCTGGCATCTCTCGCTGGTTTGAAGTGGAAAAGCGTGAAGTGGTA GAAATGAGTCCTCTGGAAAATGCAATTGAAGTGCTAGAAAATAAGAATCAGCAGCTGAAGACTCTGATTAGTCAGTGTCAGACAAGACAG ATGCAGAATATTAATCCCCTGACTATGTGCCTGAATGGAGTTATAGATGCTGCAGTTAATGGTGGCGTTTCCAGGTATCAAGAGGCATTC TTTGTCAAAGAATATATCTTAAGTCACCCTGAAGATGGGGAGAAAATTGCACGATTAAGAGAGCTGATGCTTGAGCAGGCACAGATTCTG GAATTTGGTTTGGCCGTGCATGAGAAGTTTGTACCTCAAGATATGAGACCCCTTCACAAAAAGCTGGTTGACCAATTCTTTGTGATGAAG TCGAGCTTAGGGATACAGGAGTTCTCTGCTTGTATGCAAGCCAGTCCTGTCCATTTTCCTAATGGAAGCCCTCGTGTGTGTAGAAACTCA GCACCTGCTTCTGTGAGCCCAGATGGTACCAGGGTAATTCCTAGACGCAGCCCGTTAAGTTACCCAGCTGTCAACCGATATTCTTCCTCC TCACTGTCCTCACAAGCTTCTGCTGAAGTAAGCAATATTACAGGGCAATCAGAAAGCTCTGATGAAGTCTTTAACATGCAGCCAAGTCCA TCTACCTCAAGCTTGAGTTCTACTCACTCGGCTTCACCTAATGTGACAAGTTCTGCTCCATCGAGTGCCAGAGCTTCTCCTTTGTTGTCT GACAAACACAAACATTCCCGAGAAAACTCTTGCCTGTCACCAAGAGAGAGACCATGCAGTGCCATCTATCCAACACCTGTGGAGCCTTCG CAGAGGATGCTGTTTAATCATATTGGAGACGGGGCCTTGCCACGCAGTGACCCAAATCTCTCTGCACCTGAAAAAGCTGTGAACCCCACC CCTAGCAGCTGGAGCCTGGACAGTGGGAAGGAAGCCAAGAACATGTCGGATAGTGGGAAACTTATCTCTCCCCCTGTCCCTCCAAGACCC ACACAGACTGCTTCACCAGCAAGACACACGACATCAGTATCCCCCTCGCCTGCCGGGCGATCTCCATTGAAGGGCTCTGTGCAGTCTTTC ACCCCCTCTCCAGTGGAGTACCACTCGCCAGGACTCATCTCCAACTCCCCTGTCTTGTCGGGCAGCTACAGCAGTGGGATTTCTTCTCTC AGCCGGTGCAGCACGTCGGAAACCTCAGGCTTTGAAAATCAGGTGAATGAACAGTCGGCCCCCCTGCCGGTGCCAGTGCCGGTGCCCGTG CCGAGCTACGGCGGGGAGGAGCCAGTGCGCAAGGAGAGCAAGACTCCGCCCCCGTACAGCGTCTACGAGCGGACTCTGCGGCGCCCCGTC CCGCTACCTCACAGCCTCTCCATCCCCGTCACGTCGGAGCCGCCCGCGCTGCCCCCCAAGCCTCTGGCAGCGCGATCCAGCCACCTGGAG >In-frame_PTPRZ1_ENST00000449182_chr7_121624171_+_DOCK4_ENST00000428084_chr7_111644186_-_6819nt ATGCGAATCCTAAAGCGTTTCCTCGCTTGCATTCAGCTCCTCTGTGTTTGCCGCCTGGATTGGGCTAATGGATACTACAGACAACAGAGA AAACTTGTTGAAGAGATTGGCTGGTCCTATACAGGAGCACTGAATCAAAAAAATTGGGGAAAGAAATATCCAACATGTAATAGCCCAAAA CAATCTCCTATCAATATTGATGAAGATCTTACACAAGTAAATGTGAATCTTAAGAAACTTAAATTTCAGGGTTGGGATAAAACATCATTG GAAAACACATTCATTCATAACACTGGGAAAACAGTGGAAATTAATCTCACTAATGACTACCGTGTCAGCGGAGGAGTTTCAGAAATGGTG TTTAAAGCAAGCAAGATAACTTTTCACTGGGGAAAATGCAATATGTCATCTGATGGATCAGAGCATAGTTTAGAAGGACAAAAATTTCCA CTTGAGATGCAAATCTACTGCTTTGATGCGGACCGATTTTCAAGTTTTGAGGAAGCAGTCAAAGGAAAAGGGAAGTTAAGAGCTTTATCC ATTTTGTTTGAGGTTGGGACAGAAGAAAATTTGGATTTCAAAGCGATTATTGATGGAGTCGAAAGTGTTAGTCGTTTTGGGAAGCAGGCT GCTTTAGATCCATTCATACTGTTGAACCTTCTGCCAAACTCAACTGACAAGTATTACATTTACAATGGCTCATTGACATCTCCTCCCTGC ACAGACACAGTTGACTGGATTGTTTTTAAAGATACAGTTAGCATCTCTGAAAGCCAGTTGGCTGTTTTTTGTGAAGTTCTTACAATGCAA CAATCTGGTTATGTCATGCTGATGGACTACTTACAAAACAATTTTCGAGAGCAACAGTACAAGTTCTCTAGACAGGTGTTTTCCTCATAC ACTGGAAAGGAAGAGATTCATGAAGCAGTTATTGCCAGTTTCCGAGGAACCGTTCCATATGGCCTGTCATTGGAAATTGGAGATACAGTT CAGATCCTGGAGAAGTGTGATGGCTGGTACAGAGGATTTGCCTTAAAAAACCCAAATATCAAGGGTATATTTCCTTCCAGCTACGTTCAC TTGAAAAATGCCTGTGTAAAGAACAAAGGACAATTTGAAATGGTTATTCCCACTGAAGACTCTGTTATCACAGAAATGACATCAACATTA AGAGACTGGGGAACCATGTGGAAACAACTCTATGTGCGTAATGAAGGCGATCTCTTCCACCGGCTGTGGCACATCATGAATGAAATCCTG GACCTGAGGCGGCAGGTGCTGGTGGGCCACCTCACCCACGACCGGATGAAGGACGTGAAGCGCCACATTACTGCCCGGCTTGACTGGGGC AATGAACAACTGGGACTGGACCTGGTGCCTAGGAAAGAGTACGCAATGGTGGATCCGGAAGACATCAGCATTACTGAGCTCTACCGATTG ATGGAACATCGACATCGGAAGAAAGACACCCCGGTGCAGGCCAGCAGTCACCACCTCTTTGTCCAGATGAAGAGCCTCATGTGTTCCAAC CTGGGAGAGGAGCTGGAGGTCATCTTCTCACTCTTTGACAGTAAAGAGAACCGGCCAATCAGTGAGAGATTTTTCTTGAGGCTGAATAGA AACGGGCTTCCCAAAGCCCCTGATAAACCGGAACGACATTGCTCCCTCTTTGTGGATTTGGGCAGCAGTGAGCTAAGAAAGGACATTTAT ATCACCGTGCACATTATCCGAATCGGTCGAATGGGAGCAGGAGAAAAAAAGAATGCCTGTAGTGTCCAGTACCGACGACCCTTTGGCTGT GCAGTTCTTAGCATCGCTGACCTGCTAACAGGAGAGACAAAGGATGACCTCATTCTGAAAGTATACATGTGTAACACAGAGAGTGAGTGG TACCAAATCCATGAGAACATCATCAAAAAGCTGAATGCACGTTATAACTTGACTGGCTCCAATGCAGGTTTAGCAGTTTCCTTACAGCTA TTGCACGGAGACATTGAACAAATCAGAAGGGAATATTCATCAGTATTTTCTCATGGAGTATCCATAACAAGGAAGCTGGGATTTTCAAAT ATTATTATGCCTGGTGAAATGAGGAATGATTTATATATCACTATTGAAAGGGGAGAATTTGAGAAAGGAGGGAAGAGCGTGGCCAGAAAT GTGGAAGTTACGATGTTCATTGTAGACAGTAGTGGCCAAACCCTGAAGGATTTTATCTCCTTCGGCTCTGGGGAGCCACCAGCCAGTGAG TACCACTCCTTTGTGCTTTACCATAACAACAGTCCCAGGTGGTCTGAACTGCTGAAACTTCCCATTCCTGTGGATAAATTCCGGGGTGCA CACATCCGCTTCGAGTTTCGGCATTGTTCCACAAAGGAGAAAGGAGAGAAGAAGTTGTTTGGGTTTTCTTTTGTCCCTCTGATGCAAGAA GATGGTAGGACTCTTCCAGATGGCACTCATGAGCTCATCGTGCATAAGTGTGAAGAAAACACAAATCTTCAGGATACTACCCGCTACCTC AAACTTCCCTTTTCCAAGGGCATTTTCCTTGGGAATAATAATCAAGCCATGAAGGCCACAAAGGAGTCCTTTTGTATTACATCTTTTCTC TGTTCCACAAAACTCACACAAAATGGTGATATGCTTGATCTTTTGAAATGGAGAACCCACCCAGACAAGATCACTGGCTGTCTCTCTAAA TTAAAAGAAATTGATGGCTCAGAGATAGTAAAGTTTCTGCAGGATACACTGGATACCTTATTTGGAATTTTAGATGAAAATTCCCAAAAA TATGGGTCTAAAGTGTTTGATTCTTTGGTTCACATAATAAATTTGCTGCAAGATAGCAAATTTCATCATTTTAAACCTGTAATGGACACT TACATTGAGAGTCATTTTGCTGGGGCACTTGCATACAGAGATCTCATCAAAGTGCTCAAATGGTACGTGGACCGGATCACAGAAGCAGAG CGGCAAGAGCATATCCAGGAGGTGCTGAAGGCACAAGAATACATTTTTAAGTATATAGTTCAATCTCGAAGGCTGTTTTCCCTTGCCACT GGTGGGCAAAACGAAGAGGAGTTCCGCTGCTGCATTCAGGAGCTTCTCATGTCAGTCCGTTTCTTTCTTTCGCAAGAGAGCAAAGGGTCT GGAGCATTATCTCAGTCACAGGCTGTGTTTCTGAGCTCTTTCCCTGCCGTGTACTCAGAACTGTTGAAGCTCTTTGATGTCCGGGAAGTA GCCAACTTGGTCCAGGACACCCTGGGCAGTCTGCCGACCATCCTGCATGTGGATGATTCCCTGCAGGCCATCAAACTGCAGTGCATTGGC AAAACCGTGGAAAGCCAGCTTTATACCAACCCAGATTCCCGATACATTCTTCTGCCTGTCGTGTTACATCACCTCCACATTCACTTGCAA GAACAGAAGGACCTGATCATGTGTGCACGTATCCTTAGCAACGTATTTTGTCTTATCAAGAAAAATAGCTCAGAAAAATCTGTGCTGGAG GAAATAGATGTGATAGTGGCCAGCTTGCTGGATATTCTGCTGAGGACCATATTGGAGATCACCAGCCGACCTCAGCCATCCAGCTCAGCA ATGCGGTTCCAGTTCCAGGATGTCACTGGGGAGTTTGTTGCTTGTCTCCTGTCCCTATTACGACAAATGACAGATAGACATTATCAACAG CTTCTTGATAGTTTTAATACAAAGGAAGAACTAAGGGATTTCCTGCTGCAGATATTTACTGTGTTCCGAATATTGATACGCCCGGAGATG TTTCCAAAGGACTGGACTGTTATGCGCTTGGTTGCTAACAATGTTATTATTACAACAGTTCTATACCTCTCAGATGCACTTCGTAAGAAC TTCTTAAATGAAAACTTTGATTATAAGATCTGGGATTCCTACTTTTACCTCGCAGTCATTTTTATAAACCAGTTGTGTCTGCAGTTGGAG ATGTTCACACCTTCCAAGAAGAAAAAGGTGTTAGAAAAGTATGGTGACATGCGGGTAACAATGGGTTGTGAAATTTTCAGCATGTGGCAA AACCTAGGAGAGCACAAGCTTCATTTTATCCCTGCCCTGATTGGCCCCTTCCTAGAAGTGACCTTGATACCCCAGCCAGATCTTCGGAAT GTCATGATTCCAATTTTTCATGATATGATGGACTGGGAGCAGAGGCGGAGTGGCAACTTTAAACAGGTGGAAGCCAAGCTAATTGACAAA CTGGATAGCCTGATGTCAGAAGGCAAAGGTGACGAAACATACCGCGAGCTCTTCAACAGTATAATTCCACTATTTGGTCCCTATCCTAGT CTACTAAAGAAAATTGAGCGGGAAACATGGCGGGAAAGTGGCGTTTCATTAATTGCTACTGTAACTCGTCTAATGGAGAGGTTGTTAGAT TACAGGGACTGCATGAAAATGGGAGAGGTAGATGGCAAAAAGATTGGCTGCACAGTTAGCCTTCTGAACTTCTATAAGACTGAACTGAAC AAGGAGGAGATGTATATACGCTACATTCACAAACTCTATGATCTGCATCTCAAAGCACAGAACTTTACAGAAGCTGCATATACCCTCCTC TTATATGACGAGCTACTGGAATGGTCTGATCGGCCCCTCAGGGAGTTCCTGACCTACCCCATGCAAACAGAATGGCAGCGCAAAGAGCAC CTGCACCTCACCATCATCCAGAACTTTGACAGAGGCAAATGTTGGGAGAATGGCATTATCTTGTGCCGGAAGATTGCAGAGCAGTATGAG AGTTATTATGACTACAGAAACCTGAGCAAGATGCGGATGATGGAAGCCTCTTTGTATGACAAAATTATGGACCAGCAACGTCTTGAACCA GAGTTCTTCAGAGTTGGATTTTATGGAAAAAAATTTCCATTTTTCTTAAGAAATAAGGAGTTTGTGTGTCGAGGGCATGACTACGAGAGG CTGGAAGCCTTCCAACAGAGAATGCTGAACGAGTTCCCCCATGCCATCGCCATGCAGCACGCCAACCAGCCCGATGAGACCATCTTCCAG GCAGAAGCTCAGTATTTGCAGATATATGCTGTGACTCCCATTCCAGAGAGCCAGGAGGTCCTGCAGAGAGAGGGTGTTCCGGACAACATC AAAAGCTTCTATAAAGTGAATCACATCTGGAAATTCCGCTATGACCGACCATTTCACAAAGGCACAAAAGATAAAGAGAATGAATTCAAG AGTCTCTGGGTGGAGAGAACGTCATTATACTTGGTGCAGAGTTTGCCTGGCATCTCTCGCTGGTTTGAAGTGGAAAAGCGTGAAGTGGTA GAAATGAGTCCTCTGGAAAATGCAATTGAAGTGCTAGAAAATAAGAATCAGCAGCTGAAGACTCTGATTAGTCAGTGTCAGACAAGACAG ATGCAGAATATTAATCCCCTGACTATGTGCCTGAATGGAGTTATAGATGCTGCAGTTAATGGTGGCGTTTCCAGGTATCAAGAGGCATTC TTTGTCAAAGAATATATCTTAAGTCACCCTGAAGATGGGGAGAAAATTGCACGATTAAGAGAGCTGATGCTTGAGCAGGCACAGATTCTG GAATTTGGTTTGGCCGTGCATGAGAAGTTTGTACCTCAAGATATGAGACCCCTTCACAAAAAGCTGGTTGACCAATTCTTTGTGATGAAG TCGAGCTTAGGGATACAGGAGTTCTCTGCTTGTATGCAAGCCAGTCCTGTCCATTTTCCTAATGGAAGCCCTCGTGTGTGTAGAAACTCA GCACCTGCTTCTGTGAGCCCAGATGGTACCAGGGTAATTCCTAGACGCAGCCCGTTAAGTTACCCAGCTGTCAACCGATATTCTTCCTCC TCACTGTCCTCACAAGCTTCTGCTGAAGTAAGCAATATTACAGGGCAATCAGAAAGCTCTGATGAAGTCTTTAACATGCAGCCAAGTCCA TCTACCTCAAGCTTGAGTTCTACTCACTCGGCTTCACCTAATGTGACAAGTTCTGCTCCATCGAGTGCCAGAGCTTCTCCTTTGTTGTCT GACAAACACAAACATTCCCGAGAAAACTCTTGCCTGTCACCAAGAGAGAGACCATGCAGTGCCATCTATCCAACACCTGTGGAGCCTTCG CAGAGGATGCTGTTTAATCATATTGGAGACGGGGCCTTGCCACGCAGTGACCCAAATCTCTCTGCACCTGAAAAAGCTGTGAACCCCACC CCTAGCAGCTGGAGCCTGGACAGTGGGAAGGAAGCCAAGAACATGTCGGATAGTGGGAAACTTATCTCTCCCCCTGTCCCTCCAAGACCC ACACAGACTGCTTCACCAGCAAGACACACGACATCAGTATCCCCCTCGCCTGCCGGGCGATCTCCATTGAAGGGCTCTGTGCAGTCTTTC ACCCCCTCTCCAGTGGAGTACCACTCGCCAGGACTCATCTCCAACTCCCCTGTCTTGTCGGGCAGCTACAGCAGTGGGATTTCTTCTCTC AGCCGGTGCAGCACGTCGGAAACCTCAGGCTTTGAAAATCAGGTGAATGAACAGTCGGCCCCCCTGCCGGTGCCAGTGCCGGTGCCCGTG CCGAGCTACGGCGGGGAGGAGCCAGTGCGCAAGGAGAGCAAGACTCCGCCCCCGTACAGCGTCTACGAGCGGACTCTGCGGCGCCCCGTC CCGCTACCTCACAGCCTCTCCATCCCCGTCACGTCGGAGCCGCCCGCGCTGCCCCCCAAGCCTCTGGCAGCGCGATCCAGCCACCTGGAG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_PTPRZ1_ENST00000393386_chr7_121624171_+_DOCK4_ENST00000428084_chr7_111644186_-_9026nt AGGAGCCGCGGCGCGCACAGCCGGGCTGGAGCGCGCACCCGGCACTGAGGCTTCGCTGCTCTCGGAGCGCTCAGACCGCGGCCGCCGCAG CCGGCGAAAGAGGCAAAGTCCCGCACGCCGGAGGACATGCGCCTCGGCTAGCGGCCCCGGGCCCCACCACCGTGCGGCTTTCTCCAGATT ATTCCTCTCTCGCTGTCTCTGACTGTCTCTCTCTGTCTCTGTCTCTGTCTCTCTCTCTCTCACACACACACACACACACACAAACACACA TACGCACGCACGATCTCACTTCGATCTATACACTGGAGGATTAAAACAAACAAACAAAAAAAACATTTCCTTCGCTCCCCCTCCCTCTCC ACTCTGAGAAGCAGAGGAGCCGCACGGCGAGGGGCCGCAGACCGTCTGGAAATGCGAATCCTAAAGCGTTTCCTCGCTTGCATTCAGCTC CTCTGTGTTTGCCGCCTGGATTGGGCTAATGGATACTACAGACAACAGAGAAAACTTGTTGAAGAGATTGGCTGGTCCTATACAGGAGCA CTGAATCAAAAAAATTGGGGAAAGAAATATCCAACATGTAATAGCCCAAAACAATCTCCTATCAATATTGATGAAGATCTTACACAAGTA AATGTGAATCTTAAGAAACTTAAATTTCAGGGTTGGGATAAAACATCATTGGAAAACACATTCATTCATAACACTGGGAAAACAGTGGAA ATTAATCTCACTAATGACTACCGTGTCAGCGGAGGAGTTTCAGAAATGGTGTTTAAAGCAAGCAAGATAACTTTTCACTGGGGAAAATGC AATATGTCATCTGATGGATCAGAGCATAGTTTAGAAGGACAAAAATTTCCACTTGAGATGCAAATCTACTGCTTTGATGCGGACCGATTT TCAAGTTTTGAGGAAGCAGTCAAAGGAAAAGGGAAGTTAAGAGCTTTATCCATTTTGTTTGAGGTTGGGACAGAAGAAAATTTGGATTTC AAAGCGATTATTGATGGAGTCGAAAGTGTTAGTCGTTTTGGGAAGCAGGCTGCTTTAGATCCATTCATACTGTTGAACCTTCTGCCAAAC TCAACTGACAAGTATTACATTTACAATGGCTCATTGACATCTCCTCCCTGCACAGACACAGTTGACTGGATTGTTTTTAAAGATACAGTT AGCATCTCTGAAAGCCAGTTGGCTGTTTTTTGTGAAGTTCTTACAATGCAACAATCTGGTTATGTCATGCTGATGGACTACTTACAAAAC AATTTTCGAGAGCAACAGTACAAGTTCTCTAGACAGGTGTTTTCCTCATACACTGGAAAGGAAGAGATTCATGAAGCAGTTATTGCCAGT TTCCGAGGAACCGTTCCATATGGCCTGTCATTGGAAATTGGAGATACAGTTCAGATCCTGGAGAAGTGTGATGGCTGGTACAGAGGATTT GCCTTAAAAAACCCAAATATCAAGGGTATATTTCCTTCCAGCTACGTTCACTTGAAAAATGCCTGTGTAAAGAACAAAGGACAATTTGAA ATGGTTATTCCCACTGAAGACTCTGTTATCACAGAAATGACATCAACATTAAGAGACTGGGGAACCATGTGGAAACAACTCTATGTGCGT AATGAAGGCGATCTCTTCCACCGGCTGTGGCACATCATGAATGAAATCCTGGACCTGAGGCGGCAGGTGCTGGTGGGCCACCTCACCCAC GACCGGATGAAGGACGTGAAGCGCCACATTACTGCCCGGCTTGACTGGGGCAATGAACAACTGGGACTGGACCTGGTGCCTAGGAAAGAG TACGCAATGGTGGATCCGGAAGACATCAGCATTACTGAGCTCTACCGATTGATGGAACATCGACATCGGAAGAAAGACACCCCGGTGCAG GCCAGCAGTCACCACCTCTTTGTCCAGATGAAGAGCCTCATGTGTTCCAACCTGGGAGAGGAGCTGGAGGTCATCTTCTCACTCTTTGAC AGTAAAGAGAACCGGCCAATCAGTGAGAGATTTTTCTTGAGGCTGAATAGAAACGGGCTTCCCAAAGCCCCTGATAAACCGGAACGACAT TGCTCCCTCTTTGTGGATTTGGGCAGCAGTGAGCTAAGAAAGGACATTTATATCACCGTGCACATTATCCGAATCGGTCGAATGGGAGCA GGAGAAAAAAAGAATGCCTGTAGTGTCCAGTACCGACGACCCTTTGGCTGTGCAGTTCTTAGCATCGCTGACCTGCTAACAGGAGAGACA AAGGATGACCTCATTCTGAAAGTATACATGTGTAACACAGAGAGTGAGTGGTACCAAATCCATGAGAACATCATCAAAAAGCTGAATGCA CGTTATAACTTGACTGGCTCCAATGCAGGTTTAGCAGTTTCCTTACAGCTATTGCACGGAGACATTGAACAAATCAGAAGGGAATATTCA TCAGTATTTTCTCATGGAGTATCCATAACAAGGAAGCTGGGATTTTCAAATATTATTATGCCTGGTGAAATGAGGAATGATTTATATATC ACTATTGAAAGGGGAGAATTTGAGAAAGGAGGGAAGAGCGTGGCCAGAAATGTGGAAGTTACGATGTTCATTGTAGACAGTAGTGGCCAA ACCCTGAAGGATTTTATCTCCTTCGGCTCTGGGGAGCCACCAGCCAGTGAGTACCACTCCTTTGTGCTTTACCATAACAACAGTCCCAGG TGGTCTGAACTGCTGAAACTTCCCATTCCTGTGGATAAATTCCGGGGTGCACACATCCGCTTCGAGTTTCGGCATTGTTCCACAAAGGAG AAAGGAGAGAAGAAGTTGTTTGGGTTTTCTTTTGTCCCTCTGATGCAAGAAGATGGTAGGACTCTTCCAGATGGCACTCATGAGCTCATC GTGCATAAGTGTGAAGAAAACACAAATCTTCAGGATACTACCCGCTACCTCAAACTTCCCTTTTCCAAGGGCATTTTCCTTGGGAATAAT AATCAAGCCATGAAGGCCACAAAGGAGTCCTTTTGTATTACATCTTTTCTCTGTTCCACAAAACTCACACAAAATGGTGATATGCTTGAT CTTTTGAAATGGAGAACCCACCCAGACAAGATCACTGGCTGTCTCTCTAAATTAAAAGAAATTGATGGCTCAGAGATAGTAAAGTTTCTG CAGGATACACTGGATACCTTATTTGGAATTTTAGATGAAAATTCCCAAAAATATGGGTCTAAAGTGTTTGATTCTTTGGTTCACATAATA AATTTGCTGCAAGATAGCAAATTTCATCATTTTAAACCTGTAATGGACACTTACATTGAGAGTCATTTTGCTGGGGCACTTGCATACAGA GATCTCATCAAAGTGCTCAAATGGTACGTGGACCGGATCACAGAAGCAGAGCGGCAAGAGCATATCCAGGAGGTGCTGAAGGCACAAGAA TACATTTTTAAGTATATAGTTCAATCTCGAAGGCTGTTTTCCCTTGCCACTGGTGGGCAAAACGAAGAGGAGTTCCGCTGCTGCATTCAG GAGCTTCTCATGTCAGTCCGTTTCTTTCTTTCGCAAGAGAGCAAAGGGTCTGGAGCATTATCTCAGTCACAGGCTGTGTTTCTGAGCTCT TTCCCTGCCGTGTACTCAGAACTGTTGAAGCTCTTTGATGTCCGGGAAGTAGCCAACTTGGTCCAGGACACCCTGGGCAGTCTGCCGACC ATCCTGCATGTGGATGATTCCCTGCAGGCCATCAAACTGCAGTGCATTGGCAAAACCGTGGAAAGCCAGCTTTATACCAACCCAGATTCC CGATACATTCTTCTGCCTGTCGTGTTACATCACCTCCACATTCACTTGCAAGAACAGAAGGACCTGATCATGTGTGCACGTATCCTTAGC AACGTATTTTGTCTTATCAAGAAAAATAGCTCAGAAAAATCTGTGCTGGAGGAAATAGATGTGATAGTGGCCAGCTTGCTGGATATTCTG CTGAGGACCATATTGGAGATCACCAGCCGACCTCAGCCATCCAGCTCAGCAATGCGGTTCCAGTTCCAGGATGTCACTGGGGAGTTTGTT GCTTGTCTCCTGTCCCTATTACGACAAATGACAGATAGACATTATCAACAGCTTCTTGATAGTTTTAATACAAAGGAAGAACTAAGGGAT TTCCTGCTGCAGATATTTACTGTGTTCCGAATATTGATACGCCCGGAGATGTTTCCAAAGGACTGGACTGTTATGCGCTTGGTTGCTAAC AATGTTATTATTACAACAGTTCTATACCTCTCAGATGCACTTCGTAAGAACTTCTTAAATGAAAACTTTGATTATAAGATCTGGGATTCC TACTTTTACCTCGCAGTCATTTTTATAAACCAGTTGTGTCTGCAGTTGGAGATGTTCACACCTTCCAAGAAGAAAAAGGTGTTAGAAAAG TATGGTGACATGCGGGTAACAATGGGTTGTGAAATTTTCAGCATGTGGCAAAACCTAGGAGAGCACAAGCTTCATTTTATCCCTGCCCTG ATTGGCCCCTTCCTAGAAGTGACCTTGATACCCCAGCCAGATCTTCGGAATGTCATGATTCCAATTTTTCATGATATGATGGACTGGGAG CAGAGGCGGAGTGGCAACTTTAAACAGGTGGAAGCCAAGCTAATTGACAAACTGGATAGCCTGATGTCAGAAGGCAAAGGTGACGAAACA TACCGCGAGCTCTTCAACAGTATAATTCCACTATTTGGTCCCTATCCTAGTCTACTAAAGAAAATTGAGCGGGAAACATGGCGGGAAAGT GGCGTTTCATTAATTGCTACTGTAACTCGTCTAATGGAGAGGTTGTTAGATTACAGGGACTGCATGAAAATGGGAGAGGTAGATGGCAAA AAGATTGGCTGCACAGTTAGCCTTCTGAACTTCTATAAGACTGAACTGAACAAGGAGGAGATGTATATACGCTACATTCACAAACTCTAT GATCTGCATCTCAAAGCACAGAACTTTACAGAAGCTGCATATACCCTCCTCTTATATGACGAGCTACTGGAATGGTCTGATCGGCCCCTC AGGGAGTTCCTGACCTACCCCATGCAAACAGAATGGCAGCGCAAAGAGCACCTGCACCTCACCATCATCCAGAACTTTGACAGAGGCAAA TGTTGGGAGAATGGCATTATCTTGTGCCGGAAGATTGCAGAGCAGTATGAGAGTTATTATGACTACAGAAACCTGAGCAAGATGCGGATG ATGGAAGCCTCTTTGTATGACAAAATTATGGACCAGCAACGTCTTGAACCAGAGTTCTTCAGAGTTGGATTTTATGGAAAAAAATTTCCA TTTTTCTTAAGAAATAAGGAGTTTGTGTGTCGAGGGCATGACTACGAGAGGCTGGAAGCCTTCCAACAGAGAATGCTGAACGAGTTCCCC CATGCCATCGCCATGCAGCACGCCAACCAGCCCGATGAGACCATCTTCCAGGCAGAAGCTCAGTATTTGCAGATATATGCTGTGACTCCC ATTCCAGAGAGCCAGGAGGTCCTGCAGAGAGAGGGTGTTCCGGACAACATCAAAAGCTTCTATAAAGTGAATCACATCTGGAAATTCCGC TATGACCGACCATTTCACAAAGGCACAAAAGATAAAGAGAATGAATTCAAGAGTCTCTGGGTGGAGAGAACGTCATTATACTTGGTGCAG AGTTTGCCTGGCATCTCTCGCTGGTTTGAAGTGGAAAAGCGTGAAGTGGTAGAAATGAGTCCTCTGGAAAATGCAATTGAAGTGCTAGAA AATAAGAATCAGCAGCTGAAGACTCTGATTAGTCAGTGTCAGACAAGACAGATGCAGAATATTAATCCCCTGACTATGTGCCTGAATGGA GTTATAGATGCTGCAGTTAATGGTGGCGTTTCCAGGTATCAAGAGGCATTCTTTGTCAAAGAATATATCTTAAGTCACCCTGAAGATGGG GAGAAAATTGCACGATTAAGAGAGCTGATGCTTGAGCAGGCACAGATTCTGGAATTTGGTTTGGCCGTGCATGAGAAGTTTGTACCTCAA GATATGAGACCCCTTCACAAAAAGCTGGTTGACCAATTCTTTGTGATGAAGTCGAGCTTAGGGATACAGGAGTTCTCTGCTTGTATGCAA GCCAGTCCTGTCCATTTTCCTAATGGAAGCCCTCGTGTGTGTAGAAACTCAGCACCTGCTTCTGTGAGCCCAGATGGTACCAGGGTAATT CCTAGACGCAGCCCGTTAAGTTACCCAGCTGTCAACCGATATTCTTCCTCCTCACTGTCCTCACAAGCTTCTGCTGAAGTAAGCAATATT ACAGGGCAATCAGAAAGCTCTGATGAAGTCTTTAACATGCAGCCAAGTCCATCTACCTCAAGCTTGAGTTCTACTCACTCGGCTTCACCT AATGTGACAAGTTCTGCTCCATCGAGTGCCAGAGCTTCTCCTTTGTTGTCTGACAAACACAAACATTCCCGAGAAAACTCTTGCCTGTCA CCAAGAGAGAGACCATGCAGTGCCATCTATCCAACACCTGTGGAGCCTTCGCAGAGGATGCTGTTTAATCATATTGGAGACGGGGCCTTG CCACGCAGTGACCCAAATCTCTCTGCACCTGAAAAAGCTGTGAACCCCACCCCTAGCAGCTGGAGCCTGGACAGTGGGAAGGAAGCCAAG AACATGTCGGATAGTGGGAAACTTATCTCTCCCCCTGTCCCTCCAAGACCCACACAGACTGCTTCACCAGCAAGACACACGACATCAGTA TCCCCCTCGCCTGCCGGGCGATCTCCATTGAAGGGCTCTGTGCAGTCTTTCACCCCCTCTCCAGTGGAGTACCACTCGCCAGGACTCATC TCCAACTCCCCTGTCTTGTCGGGCAGCTACAGCAGTGGGATTTCTTCTCTCAGCCGGTGCAGCACGTCGGAAACCTCAGGCTTTGAAAAT CAGGTGAATGAACAGTCGGCCCCCCTGCCGGTGCCAGTGCCGGTGCCCGTGCCGAGCTACGGCGGGGAGGAGCCAGTGCGCAAGGAGAGC AAGACTCCGCCCCCGTACAGCGTCTACGAGCGGACTCTGCGGCGCCCCGTCCCGCTACCTCACAGCCTCTCCATCCCCGTCACGTCGGAG CCGCCCGCGCTGCCCCCCAAGCCTCTGGCAGCGCGATCCAGCCACCTGGAGAATGGGGCCCGGAGGACTGACCCCGGCCCGCGGCCCAGG CCCCTGCCCCGCAAGGTCTCTCAGTTATAAGTCACTTTTCTATGTACCTGCGATGCATTCTTTGCCCGTTTACAAAATAAGAAGTATGAT GAGAAGACATTTAGTGTAGGCACTTTAATAACTTACTCAGCTCCTTCGATGAATGGAATTAAAACTTGCTTATTAAATATCATGTTGCAC AATATTAAAAGTTGCTGATCTAAAACGCCAGATGTTAAATGAAGTATGGCTGAATTTCATTAAAACGTTTCTCATTTGGAAGTGGTAAAT AGTGATAAAGACTCCTTTTGTACCTTTTTATGTTCACTTTTTTTTATATAGTTTAATCTTAAAACCAATACGATATTGTCAAACGATACA ATGTGTGACAATGTTGTATCGTTTTTACTGAATACTTGATACTTGGAGAAAGCTTATTAAGTCAGTGCACATCCTAACACAGTGGTCCTT ATTTTAGAAGACTTCTGTAAATAAGGCAAGGTTTATCAGTGCAGATCATCAGAATTAAAGTTCAAGCAGGCGAGCAAGACAGTATACTTA AGGGGTTGCAAAGCTTGGGACTGGAAATTGTTTTGTTCTTGAAACAAAATACTTCTTTAAGGTTGCTTTTGCTGTTTGACTGCTGTCTAC ATTCGTAAAATTCTATTTTGTGAATTGGTAGCTAAATCCCTTACTACCCTGACACCGTGGTATCTACTGTATTTCTTTTCAAGGTGCAAT TTGCTTCAGAGTTCCAATCAGCTAGATTAAGCAAGAGGCTCCAGAAGAAATGTTTACTTGAATTTTGCGCTTCCTTTCTTGATAGTTTCC TATATAAAATTTGTCATTGAACAAGAGCAAATGCTGAAGTATTAATGAGGCACAAATGACTGTGCCCCATTAGCAAGAATTCAGGAATCA ATACAGACAGTATTAAATTAATAGCTTAAGTGAAGAAAAAAAAAACTTAGTGAAAATGTATTAGCACGATTAAATGGCAAAAGGACTTAT AAAAGGCAAGGGCATTAACTTTCAGTCCTGCACAAAATAAAAAATTCCTCACGACTCTCCACTTTTACCAGTGGAGTTTGTCTTAGCTGA CCTGTCGTCTTTCTCTTGAAGGAGGATTGCTGTAGACTTCTCTAGCTTGAATATTGCAACATAGCATCTTAGGTCTAGATAGGGATGCTA ATGCCAGTTGTAGAAGTGTGAAAAAAGCACCTTGTATGTAGTAATGTATTTTATATCTTTGTTTTTTCTTTTACTGACTGTTTATAACAC TCAATTGACAATAGATATGAACTGTATTTTAAATCATACTGTTAAATATTTTCCCTCTTTTGTTGGGAAGCTCATTTTAGTTTAACCATG TTTGTTTTGTTGGTAGCTTACCTGGAAGGCAGTGACCACTTTTTTATATTCTCTTAATGAAACCATTCAGCAGGTATATGCTGTTGAGGC TGGTTATAGAGGTTTTCTATAATAAATGTTCAAGTATTTTTGTATATAACTGGTTAATTTTAATAAGAGATACCATTATGTGTAAAAAAA AGTAAAAATAAACGCAAACAGTTGTTGATGCAGTATGATTGTTATAATTATGCCAAATACTTTACGTATGGAAAAAGAATATTTGTACAT ATGTGCTTTTAACAATTCTGCCATATTGACTTTACAATTTTGAATGTCGGAAAAATTAATATATGTTAAATATTTATGTTTAGTGAAAGT GTTCATAATTGAGAAAAGGAACATATGCATTTTAGCTTTGTATCTTGCAAGTTTTGCAGTCAGAAATTTTTTGAACTAGCTTTTGCTTTT >In-frame_PTPRZ1_ENST00000449182_chr7_121624171_+_DOCK4_ENST00000428084_chr7_111644186_-_8754nt CGCACGCACGATCTCACTTCGATCTATACACTGGAGGATTAAAACAAACAAACAAAAAAAACATTTCCTTCGCTCCCCCTCCCTCTCCAC TCTGAGAAGCAGAGGAGCCGCACGGCGAGGGGCCGCAGACCGTCTGGAAATGCGAATCCTAAAGCGTTTCCTCGCTTGCATTCAGCTCCT CTGTGTTTGCCGCCTGGATTGGGCTAATGGATACTACAGACAACAGAGAAAACTTGTTGAAGAGATTGGCTGGTCCTATACAGGAGCACT GAATCAAAAAAATTGGGGAAAGAAATATCCAACATGTAATAGCCCAAAACAATCTCCTATCAATATTGATGAAGATCTTACACAAGTAAA TGTGAATCTTAAGAAACTTAAATTTCAGGGTTGGGATAAAACATCATTGGAAAACACATTCATTCATAACACTGGGAAAACAGTGGAAAT TAATCTCACTAATGACTACCGTGTCAGCGGAGGAGTTTCAGAAATGGTGTTTAAAGCAAGCAAGATAACTTTTCACTGGGGAAAATGCAA TATGTCATCTGATGGATCAGAGCATAGTTTAGAAGGACAAAAATTTCCACTTGAGATGCAAATCTACTGCTTTGATGCGGACCGATTTTC AAGTTTTGAGGAAGCAGTCAAAGGAAAAGGGAAGTTAAGAGCTTTATCCATTTTGTTTGAGGTTGGGACAGAAGAAAATTTGGATTTCAA AGCGATTATTGATGGAGTCGAAAGTGTTAGTCGTTTTGGGAAGCAGGCTGCTTTAGATCCATTCATACTGTTGAACCTTCTGCCAAACTC AACTGACAAGTATTACATTTACAATGGCTCATTGACATCTCCTCCCTGCACAGACACAGTTGACTGGATTGTTTTTAAAGATACAGTTAG CATCTCTGAAAGCCAGTTGGCTGTTTTTTGTGAAGTTCTTACAATGCAACAATCTGGTTATGTCATGCTGATGGACTACTTACAAAACAA TTTTCGAGAGCAACAGTACAAGTTCTCTAGACAGGTGTTTTCCTCATACACTGGAAAGGAAGAGATTCATGAAGCAGTTATTGCCAGTTT CCGAGGAACCGTTCCATATGGCCTGTCATTGGAAATTGGAGATACAGTTCAGATCCTGGAGAAGTGTGATGGCTGGTACAGAGGATTTGC CTTAAAAAACCCAAATATCAAGGGTATATTTCCTTCCAGCTACGTTCACTTGAAAAATGCCTGTGTAAAGAACAAAGGACAATTTGAAAT GGTTATTCCCACTGAAGACTCTGTTATCACAGAAATGACATCAACATTAAGAGACTGGGGAACCATGTGGAAACAACTCTATGTGCGTAA TGAAGGCGATCTCTTCCACCGGCTGTGGCACATCATGAATGAAATCCTGGACCTGAGGCGGCAGGTGCTGGTGGGCCACCTCACCCACGA CCGGATGAAGGACGTGAAGCGCCACATTACTGCCCGGCTTGACTGGGGCAATGAACAACTGGGACTGGACCTGGTGCCTAGGAAAGAGTA CGCAATGGTGGATCCGGAAGACATCAGCATTACTGAGCTCTACCGATTGATGGAACATCGACATCGGAAGAAAGACACCCCGGTGCAGGC CAGCAGTCACCACCTCTTTGTCCAGATGAAGAGCCTCATGTGTTCCAACCTGGGAGAGGAGCTGGAGGTCATCTTCTCACTCTTTGACAG TAAAGAGAACCGGCCAATCAGTGAGAGATTTTTCTTGAGGCTGAATAGAAACGGGCTTCCCAAAGCCCCTGATAAACCGGAACGACATTG CTCCCTCTTTGTGGATTTGGGCAGCAGTGAGCTAAGAAAGGACATTTATATCACCGTGCACATTATCCGAATCGGTCGAATGGGAGCAGG AGAAAAAAAGAATGCCTGTAGTGTCCAGTACCGACGACCCTTTGGCTGTGCAGTTCTTAGCATCGCTGACCTGCTAACAGGAGAGACAAA GGATGACCTCATTCTGAAAGTATACATGTGTAACACAGAGAGTGAGTGGTACCAAATCCATGAGAACATCATCAAAAAGCTGAATGCACG TTATAACTTGACTGGCTCCAATGCAGGTTTAGCAGTTTCCTTACAGCTATTGCACGGAGACATTGAACAAATCAGAAGGGAATATTCATC AGTATTTTCTCATGGAGTATCCATAACAAGGAAGCTGGGATTTTCAAATATTATTATGCCTGGTGAAATGAGGAATGATTTATATATCAC TATTGAAAGGGGAGAATTTGAGAAAGGAGGGAAGAGCGTGGCCAGAAATGTGGAAGTTACGATGTTCATTGTAGACAGTAGTGGCCAAAC CCTGAAGGATTTTATCTCCTTCGGCTCTGGGGAGCCACCAGCCAGTGAGTACCACTCCTTTGTGCTTTACCATAACAACAGTCCCAGGTG GTCTGAACTGCTGAAACTTCCCATTCCTGTGGATAAATTCCGGGGTGCACACATCCGCTTCGAGTTTCGGCATTGTTCCACAAAGGAGAA AGGAGAGAAGAAGTTGTTTGGGTTTTCTTTTGTCCCTCTGATGCAAGAAGATGGTAGGACTCTTCCAGATGGCACTCATGAGCTCATCGT GCATAAGTGTGAAGAAAACACAAATCTTCAGGATACTACCCGCTACCTCAAACTTCCCTTTTCCAAGGGCATTTTCCTTGGGAATAATAA TCAAGCCATGAAGGCCACAAAGGAGTCCTTTTGTATTACATCTTTTCTCTGTTCCACAAAACTCACACAAAATGGTGATATGCTTGATCT TTTGAAATGGAGAACCCACCCAGACAAGATCACTGGCTGTCTCTCTAAATTAAAAGAAATTGATGGCTCAGAGATAGTAAAGTTTCTGCA GGATACACTGGATACCTTATTTGGAATTTTAGATGAAAATTCCCAAAAATATGGGTCTAAAGTGTTTGATTCTTTGGTTCACATAATAAA TTTGCTGCAAGATAGCAAATTTCATCATTTTAAACCTGTAATGGACACTTACATTGAGAGTCATTTTGCTGGGGCACTTGCATACAGAGA TCTCATCAAAGTGCTCAAATGGTACGTGGACCGGATCACAGAAGCAGAGCGGCAAGAGCATATCCAGGAGGTGCTGAAGGCACAAGAATA CATTTTTAAGTATATAGTTCAATCTCGAAGGCTGTTTTCCCTTGCCACTGGTGGGCAAAACGAAGAGGAGTTCCGCTGCTGCATTCAGGA GCTTCTCATGTCAGTCCGTTTCTTTCTTTCGCAAGAGAGCAAAGGGTCTGGAGCATTATCTCAGTCACAGGCTGTGTTTCTGAGCTCTTT CCCTGCCGTGTACTCAGAACTGTTGAAGCTCTTTGATGTCCGGGAAGTAGCCAACTTGGTCCAGGACACCCTGGGCAGTCTGCCGACCAT CCTGCATGTGGATGATTCCCTGCAGGCCATCAAACTGCAGTGCATTGGCAAAACCGTGGAAAGCCAGCTTTATACCAACCCAGATTCCCG ATACATTCTTCTGCCTGTCGTGTTACATCACCTCCACATTCACTTGCAAGAACAGAAGGACCTGATCATGTGTGCACGTATCCTTAGCAA CGTATTTTGTCTTATCAAGAAAAATAGCTCAGAAAAATCTGTGCTGGAGGAAATAGATGTGATAGTGGCCAGCTTGCTGGATATTCTGCT GAGGACCATATTGGAGATCACCAGCCGACCTCAGCCATCCAGCTCAGCAATGCGGTTCCAGTTCCAGGATGTCACTGGGGAGTTTGTTGC TTGTCTCCTGTCCCTATTACGACAAATGACAGATAGACATTATCAACAGCTTCTTGATAGTTTTAATACAAAGGAAGAACTAAGGGATTT CCTGCTGCAGATATTTACTGTGTTCCGAATATTGATACGCCCGGAGATGTTTCCAAAGGACTGGACTGTTATGCGCTTGGTTGCTAACAA TGTTATTATTACAACAGTTCTATACCTCTCAGATGCACTTCGTAAGAACTTCTTAAATGAAAACTTTGATTATAAGATCTGGGATTCCTA CTTTTACCTCGCAGTCATTTTTATAAACCAGTTGTGTCTGCAGTTGGAGATGTTCACACCTTCCAAGAAGAAAAAGGTGTTAGAAAAGTA TGGTGACATGCGGGTAACAATGGGTTGTGAAATTTTCAGCATGTGGCAAAACCTAGGAGAGCACAAGCTTCATTTTATCCCTGCCCTGAT TGGCCCCTTCCTAGAAGTGACCTTGATACCCCAGCCAGATCTTCGGAATGTCATGATTCCAATTTTTCATGATATGATGGACTGGGAGCA GAGGCGGAGTGGCAACTTTAAACAGGTGGAAGCCAAGCTAATTGACAAACTGGATAGCCTGATGTCAGAAGGCAAAGGTGACGAAACATA CCGCGAGCTCTTCAACAGTATAATTCCACTATTTGGTCCCTATCCTAGTCTACTAAAGAAAATTGAGCGGGAAACATGGCGGGAAAGTGG CGTTTCATTAATTGCTACTGTAACTCGTCTAATGGAGAGGTTGTTAGATTACAGGGACTGCATGAAAATGGGAGAGGTAGATGGCAAAAA GATTGGCTGCACAGTTAGCCTTCTGAACTTCTATAAGACTGAACTGAACAAGGAGGAGATGTATATACGCTACATTCACAAACTCTATGA TCTGCATCTCAAAGCACAGAACTTTACAGAAGCTGCATATACCCTCCTCTTATATGACGAGCTACTGGAATGGTCTGATCGGCCCCTCAG GGAGTTCCTGACCTACCCCATGCAAACAGAATGGCAGCGCAAAGAGCACCTGCACCTCACCATCATCCAGAACTTTGACAGAGGCAAATG TTGGGAGAATGGCATTATCTTGTGCCGGAAGATTGCAGAGCAGTATGAGAGTTATTATGACTACAGAAACCTGAGCAAGATGCGGATGAT GGAAGCCTCTTTGTATGACAAAATTATGGACCAGCAACGTCTTGAACCAGAGTTCTTCAGAGTTGGATTTTATGGAAAAAAATTTCCATT TTTCTTAAGAAATAAGGAGTTTGTGTGTCGAGGGCATGACTACGAGAGGCTGGAAGCCTTCCAACAGAGAATGCTGAACGAGTTCCCCCA TGCCATCGCCATGCAGCACGCCAACCAGCCCGATGAGACCATCTTCCAGGCAGAAGCTCAGTATTTGCAGATATATGCTGTGACTCCCAT TCCAGAGAGCCAGGAGGTCCTGCAGAGAGAGGGTGTTCCGGACAACATCAAAAGCTTCTATAAAGTGAATCACATCTGGAAATTCCGCTA TGACCGACCATTTCACAAAGGCACAAAAGATAAAGAGAATGAATTCAAGAGTCTCTGGGTGGAGAGAACGTCATTATACTTGGTGCAGAG TTTGCCTGGCATCTCTCGCTGGTTTGAAGTGGAAAAGCGTGAAGTGGTAGAAATGAGTCCTCTGGAAAATGCAATTGAAGTGCTAGAAAA TAAGAATCAGCAGCTGAAGACTCTGATTAGTCAGTGTCAGACAAGACAGATGCAGAATATTAATCCCCTGACTATGTGCCTGAATGGAGT TATAGATGCTGCAGTTAATGGTGGCGTTTCCAGGTATCAAGAGGCATTCTTTGTCAAAGAATATATCTTAAGTCACCCTGAAGATGGGGA GAAAATTGCACGATTAAGAGAGCTGATGCTTGAGCAGGCACAGATTCTGGAATTTGGTTTGGCCGTGCATGAGAAGTTTGTACCTCAAGA TATGAGACCCCTTCACAAAAAGCTGGTTGACCAATTCTTTGTGATGAAGTCGAGCTTAGGGATACAGGAGTTCTCTGCTTGTATGCAAGC CAGTCCTGTCCATTTTCCTAATGGAAGCCCTCGTGTGTGTAGAAACTCAGCACCTGCTTCTGTGAGCCCAGATGGTACCAGGGTAATTCC TAGACGCAGCCCGTTAAGTTACCCAGCTGTCAACCGATATTCTTCCTCCTCACTGTCCTCACAAGCTTCTGCTGAAGTAAGCAATATTAC AGGGCAATCAGAAAGCTCTGATGAAGTCTTTAACATGCAGCCAAGTCCATCTACCTCAAGCTTGAGTTCTACTCACTCGGCTTCACCTAA TGTGACAAGTTCTGCTCCATCGAGTGCCAGAGCTTCTCCTTTGTTGTCTGACAAACACAAACATTCCCGAGAAAACTCTTGCCTGTCACC AAGAGAGAGACCATGCAGTGCCATCTATCCAACACCTGTGGAGCCTTCGCAGAGGATGCTGTTTAATCATATTGGAGACGGGGCCTTGCC ACGCAGTGACCCAAATCTCTCTGCACCTGAAAAAGCTGTGAACCCCACCCCTAGCAGCTGGAGCCTGGACAGTGGGAAGGAAGCCAAGAA CATGTCGGATAGTGGGAAACTTATCTCTCCCCCTGTCCCTCCAAGACCCACACAGACTGCTTCACCAGCAAGACACACGACATCAGTATC CCCCTCGCCTGCCGGGCGATCTCCATTGAAGGGCTCTGTGCAGTCTTTCACCCCCTCTCCAGTGGAGTACCACTCGCCAGGACTCATCTC CAACTCCCCTGTCTTGTCGGGCAGCTACAGCAGTGGGATTTCTTCTCTCAGCCGGTGCAGCACGTCGGAAACCTCAGGCTTTGAAAATCA GGTGAATGAACAGTCGGCCCCCCTGCCGGTGCCAGTGCCGGTGCCCGTGCCGAGCTACGGCGGGGAGGAGCCAGTGCGCAAGGAGAGCAA GACTCCGCCCCCGTACAGCGTCTACGAGCGGACTCTGCGGCGCCCCGTCCCGCTACCTCACAGCCTCTCCATCCCCGTCACGTCGGAGCC GCCCGCGCTGCCCCCCAAGCCTCTGGCAGCGCGATCCAGCCACCTGGAGAATGGGGCCCGGAGGACTGACCCCGGCCCGCGGCCCAGGCC CCTGCCCCGCAAGGTCTCTCAGTTATAAGTCACTTTTCTATGTACCTGCGATGCATTCTTTGCCCGTTTACAAAATAAGAAGTATGATGA GAAGACATTTAGTGTAGGCACTTTAATAACTTACTCAGCTCCTTCGATGAATGGAATTAAAACTTGCTTATTAAATATCATGTTGCACAA TATTAAAAGTTGCTGATCTAAAACGCCAGATGTTAAATGAAGTATGGCTGAATTTCATTAAAACGTTTCTCATTTGGAAGTGGTAAATAG TGATAAAGACTCCTTTTGTACCTTTTTATGTTCACTTTTTTTTATATAGTTTAATCTTAAAACCAATACGATATTGTCAAACGATACAAT GTGTGACAATGTTGTATCGTTTTTACTGAATACTTGATACTTGGAGAAAGCTTATTAAGTCAGTGCACATCCTAACACAGTGGTCCTTAT TTTAGAAGACTTCTGTAAATAAGGCAAGGTTTATCAGTGCAGATCATCAGAATTAAAGTTCAAGCAGGCGAGCAAGACAGTATACTTAAG GGGTTGCAAAGCTTGGGACTGGAAATTGTTTTGTTCTTGAAACAAAATACTTCTTTAAGGTTGCTTTTGCTGTTTGACTGCTGTCTACAT TCGTAAAATTCTATTTTGTGAATTGGTAGCTAAATCCCTTACTACCCTGACACCGTGGTATCTACTGTATTTCTTTTCAAGGTGCAATTT GCTTCAGAGTTCCAATCAGCTAGATTAAGCAAGAGGCTCCAGAAGAAATGTTTACTTGAATTTTGCGCTTCCTTTCTTGATAGTTTCCTA TATAAAATTTGTCATTGAACAAGAGCAAATGCTGAAGTATTAATGAGGCACAAATGACTGTGCCCCATTAGCAAGAATTCAGGAATCAAT ACAGACAGTATTAAATTAATAGCTTAAGTGAAGAAAAAAAAAACTTAGTGAAAATGTATTAGCACGATTAAATGGCAAAAGGACTTATAA AAGGCAAGGGCATTAACTTTCAGTCCTGCACAAAATAAAAAATTCCTCACGACTCTCCACTTTTACCAGTGGAGTTTGTCTTAGCTGACC TGTCGTCTTTCTCTTGAAGGAGGATTGCTGTAGACTTCTCTAGCTTGAATATTGCAACATAGCATCTTAGGTCTAGATAGGGATGCTAAT GCCAGTTGTAGAAGTGTGAAAAAAGCACCTTGTATGTAGTAATGTATTTTATATCTTTGTTTTTTCTTTTACTGACTGTTTATAACACTC AATTGACAATAGATATGAACTGTATTTTAAATCATACTGTTAAATATTTTCCCTCTTTTGTTGGGAAGCTCATTTTAGTTTAACCATGTT TGTTTTGTTGGTAGCTTACCTGGAAGGCAGTGACCACTTTTTTATATTCTCTTAATGAAACCATTCAGCAGGTATATGCTGTTGAGGCTG GTTATAGAGGTTTTCTATAATAAATGTTCAAGTATTTTTGTATATAACTGGTTAATTTTAATAAGAGATACCATTATGTGTAAAAAAAAG TAAAAATAAACGCAAACAGTTGTTGATGCAGTATGATTGTTATAATTATGCCAAATACTTTACGTATGGAAAAAGAATATTTGTACATAT GTGCTTTTAACAATTCTGCCATATTGACTTTACAATTTTGAATGTCGGAAAAATTAATATATGTTAAATATTTATGTTTAGTGAAAGTGT TCATAATTGAGAAAAGGAACATATGCATTTTAGCTTTGTATCTTGCAAGTTTTGCAGTCAGAAATTTTTTGAACTAGCTTTTGCTTTTGA |
Top |
FusionGenePPI for PTPRZ1_DOCK4 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| PTPRZ1 | CNTN1, PTN, CTNNB1, GIT1, TNR, HMGB1, MDK, LGALS3, VEGFA, NCL | DOCK4 | HNRNPL, YWHAB, RNF115, FASLG, GRK5, EGFR, EIF4A3, MAGOH, GRB2, NPM1, ELMO1, NTRK1, ELMO3, ARRB1, ERMAP, STAT1, VSIG8 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
RelatedDrugs for PTPRZ1_DOCK4 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for PTPRZ1_DOCK4 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | PTPRZ1 | C0036341 | Schizophrenia | 3 | PSYGENET |
| Hgene | PTPRZ1 | C0032273 | Pneumoconiosis | 1 | CTD_human |
| Hgene | PTPRZ1 | C0079487 | Helicobacter Infections | 1 | CTD_human |
| Tgene | DOCK4 | C0036341 | Schizophrenia | 2 | PSYGENET |
| Tgene | DOCK4 | C0004352 | Autistic Disorder | 1 | CTD_human |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
|