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Fusion gene ID: 29608 |
FusionGeneSummary for PTPRU_UBIAD1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PTPRU_UBIAD1 | Fusion gene ID: 29608 | Hgene | Tgene | Gene symbol | PTPRU | UBIAD1 | Gene ID | 10076 | 29914 |
| Gene name | protein tyrosine phosphatase, receptor type U | UbiA prenyltransferase domain containing 1 | |
| Synonyms | FMI|PCP-2|PTP|PTP-J|PTP-PI|PTP-RO|PTPPSI|PTPRO|PTPU2|R-PTP-PSI|R-PTP-U|hPTP-J | SCCD|TERE1 | |
| Cytomap | 1p35.3 | 1p36.22 | |
| Type of gene | protein-coding | protein-coding | |
| Description | receptor-type tyrosine-protein phosphatase UPTP piReceptor protein tyrosine phosphatase hPTP-Jpancreatic carcinoma phosphatase 2pi R-PTP-Psiprotein-tyrosine phosphatase Jprotein-tyrosine phosphatase piprotein-tyrosine phosphatase receptor omicronr | ubiA prenyltransferase domain-containing protein 1transitional epithelia response proteintransitional epithelial response protein 1 | |
| Modification date | 20180522 | 20180526 | |
| UniProtAcc | Q92729 | Q9Y5Z9 | |
| Ensembl transtripts involved in fusion gene | ENST00000345512, ENST00000373779, ENST00000356870, ENST00000323874, ENST00000428026, ENST00000460170, ENST00000415600, | ENST00000376810, ENST00000376804, | |
| Fusion gene scores | * DoF score | 6 X 5 X 6=180 | 2 X 2 X 2=8 |
| # samples | 6 | 3 | |
| ** MAII score | log2(6/180*10)=-1.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/8*10)=1.90689059560852 | |
| Context | PubMed: PTPRU [Title/Abstract] AND UBIAD1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. Tumor suppressor gene involved fusion gene, retained protein feature but frameshift. DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | PTPRU | GO:0006470 | protein dephosphorylation | 12501215 |
| Hgene | PTPRU | GO:0008285 | negative regulation of cell proliferation | 16574648 |
| Hgene | PTPRU | GO:0030336 | negative regulation of cell migration | 12501215|16574648 |
| Hgene | PTPRU | GO:0034394 | protein localization to cell surface | 16574648 |
| Hgene | PTPRU | GO:0060070 | canonical Wnt signaling pathway | 16574648 |
| Hgene | PTPRU | GO:0098609 | cell-cell adhesion | 16574648 |
| Tgene | UBIAD1 | GO:0042371 | vitamin K biosynthetic process | 20953171 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | GBM | TCGA-32-5222-01A | PTPRU | chr1 | 29563229 | + | UBIAD1 | chr1 | 11345701 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000345512 | ENST00000376810 | PTPRU | chr1 | 29563229 | + | UBIAD1 | chr1 | 11345701 | + |
| 5CDS-intron | ENST00000345512 | ENST00000376804 | PTPRU | chr1 | 29563229 | + | UBIAD1 | chr1 | 11345701 | + |
| In-frame | ENST00000373779 | ENST00000376810 | PTPRU | chr1 | 29563229 | + | UBIAD1 | chr1 | 11345701 | + |
| 5CDS-intron | ENST00000373779 | ENST00000376804 | PTPRU | chr1 | 29563229 | + | UBIAD1 | chr1 | 11345701 | + |
| In-frame | ENST00000356870 | ENST00000376810 | PTPRU | chr1 | 29563229 | + | UBIAD1 | chr1 | 11345701 | + |
| 5CDS-intron | ENST00000356870 | ENST00000376804 | PTPRU | chr1 | 29563229 | + | UBIAD1 | chr1 | 11345701 | + |
| In-frame | ENST00000323874 | ENST00000376810 | PTPRU | chr1 | 29563229 | + | UBIAD1 | chr1 | 11345701 | + |
| 5CDS-intron | ENST00000323874 | ENST00000376804 | PTPRU | chr1 | 29563229 | + | UBIAD1 | chr1 | 11345701 | + |
| In-frame | ENST00000428026 | ENST00000376810 | PTPRU | chr1 | 29563229 | + | UBIAD1 | chr1 | 11345701 | + |
| 5CDS-intron | ENST00000428026 | ENST00000376804 | PTPRU | chr1 | 29563229 | + | UBIAD1 | chr1 | 11345701 | + |
| In-frame | ENST00000460170 | ENST00000376810 | PTPRU | chr1 | 29563229 | + | UBIAD1 | chr1 | 11345701 | + |
| 5CDS-intron | ENST00000460170 | ENST00000376804 | PTPRU | chr1 | 29563229 | + | UBIAD1 | chr1 | 11345701 | + |
| intron-3CDS | ENST00000415600 | ENST00000376810 | PTPRU | chr1 | 29563229 | + | UBIAD1 | chr1 | 11345701 | + |
| intron-intron | ENST00000415600 | ENST00000376804 | PTPRU | chr1 | 29563229 | + | UBIAD1 | chr1 | 11345701 | + |
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FusionProtFeatures for PTPRU_UBIAD1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| PTPRU | UBIAD1 |
| Prenyltransferase that mediates the formation ofmenaquinone-4 (MK-4) and coenzyme Q10. MK-4 is a vitamin K2isoform present at high concentrations in the brain, kidney andpancreas, and is required for endothelial cell development.Mediates the conversion of phylloquinone (PK) into MK-4, probablyby cleaving the side chain of phylloquinone (PK) to release 2-methyl-1,4-naphthoquinone (menadione; K3) and then prenylating itwith geranylgeranyl pyrophosphate (GGPP) to form MK-4. Also playsa role in cardiovascular development independently of MK-4biosynthesis, by acting as a coenzyme Q10 biosynthetic enzyme:coenzyme Q10, also named ubiquinone, plays a important antioxidantrole in the cardiovascular system. Mediates biosynthesis ofcoenzyme Q10 in the Golgi membrane, leading to protectcardiovascular tissues from NOS3/eNOS-dependent oxidative stress.{ECO:0000269|PubMed:20953171, ECO:0000269|PubMed:23374346}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >UBIAD1 | chr1:29563229 | chr1:11345701 | ENST00000376804 | + | 0 | 2 | 134_154 | -2 | 180 | Transmembrane | Helical |
| Tgene | >UBIAD1 | chr1:29563229 | chr1:11345701 | ENST00000376804 | + | 0 | 2 | 160_180 | -2 | 180 | Transmembrane | Helical |
| Tgene | >UBIAD1 | chr1:29563229 | chr1:11345701 | ENST00000376804 | + | 0 | 2 | 188_208 | -2 | 180 | Transmembrane | Helical |
| Tgene | >UBIAD1 | chr1:29563229 | chr1:11345701 | ENST00000376804 | + | 0 | 2 | 209_229 | -2 | 180 | Transmembrane | Helical |
| Tgene | >UBIAD1 | chr1:29563229 | chr1:11345701 | ENST00000376804 | + | 0 | 2 | 245_267 | -2 | 180 | Transmembrane | Helical |
| Tgene | >UBIAD1 | chr1:29563229 | chr1:11345701 | ENST00000376804 | + | 0 | 2 | 277_297 | -2 | 180 | Transmembrane | Helical |
| Tgene | >UBIAD1 | chr1:29563229 | chr1:11345701 | ENST00000376804 | + | 0 | 2 | 315_335 | -2 | 180 | Transmembrane | Helical |
| Tgene | >UBIAD1 | chr1:29563229 | chr1:11345701 | ENST00000376804 | + | 0 | 2 | 83_103 | -2 | 180 | Transmembrane | Helical |
| Tgene | >UBIAD1 | chr1:29563229 | chr1:11345701 | ENST00000376810 | + | 0 | 2 | 188_208 | 176 | 339 | Transmembrane | Helical |
| Tgene | >UBIAD1 | chr1:29563229 | chr1:11345701 | ENST00000376810 | + | 0 | 2 | 209_229 | 176 | 339 | Transmembrane | Helical |
| Tgene | >UBIAD1 | chr1:29563229 | chr1:11345701 | ENST00000376810 | + | 0 | 2 | 245_267 | 176 | 339 | Transmembrane | Helical |
| Tgene | >UBIAD1 | chr1:29563229 | chr1:11345701 | ENST00000376810 | + | 0 | 2 | 277_297 | 176 | 339 | Transmembrane | Helical |
| Tgene | >UBIAD1 | chr1:29563229 | chr1:11345701 | ENST00000376810 | + | 0 | 2 | 315_335 | 176 | 339 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000345512 | + | 1 | 31 | 1176_1439 | 24 | 1447 | Domain | Tyrosine-protein phosphatase 2 |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000345512 | + | 1 | 31 | 190_275 | 24 | 1447 | Domain | Note=Ig-like C2-type |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000345512 | + | 1 | 31 | 25_188 | 24 | 1447 | Domain | MAM |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000345512 | + | 1 | 31 | 288_383 | 24 | 1447 | Domain | Fibronectin type-III 1 |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000345512 | + | 1 | 31 | 386_484 | 24 | 1447 | Domain | Fibronectin type-III 2 |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000345512 | + | 1 | 31 | 485_591 | 24 | 1447 | Domain | Fibronectin type-III 3 |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000345512 | + | 1 | 31 | 592_674 | 24 | 1447 | Domain | Fibronectin type-III 4 |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000345512 | + | 1 | 31 | 888_1144 | 24 | 1447 | Domain | Tyrosine-protein phosphatase 1 |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000373779 | + | 1 | 30 | 1176_1439 | 24 | 1437 | Domain | Tyrosine-protein phosphatase 2 |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000373779 | + | 1 | 30 | 190_275 | 24 | 1437 | Domain | Note=Ig-like C2-type |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000373779 | + | 1 | 30 | 25_188 | 24 | 1437 | Domain | MAM |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000373779 | + | 1 | 30 | 288_383 | 24 | 1437 | Domain | Fibronectin type-III 1 |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000373779 | + | 1 | 30 | 386_484 | 24 | 1437 | Domain | Fibronectin type-III 2 |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000373779 | + | 1 | 30 | 485_591 | 24 | 1437 | Domain | Fibronectin type-III 3 |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000373779 | + | 1 | 30 | 592_674 | 24 | 1437 | Domain | Fibronectin type-III 4 |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000373779 | + | 1 | 30 | 888_1144 | 24 | 1437 | Domain | Tyrosine-protein phosphatase 1 |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000428026 | + | 1 | 30 | 1176_1439 | 24 | 1434 | Domain | Tyrosine-protein phosphatase 2 |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000428026 | + | 1 | 30 | 190_275 | 24 | 1434 | Domain | Note=Ig-like C2-type |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000428026 | + | 1 | 30 | 25_188 | 24 | 1434 | Domain | MAM |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000428026 | + | 1 | 30 | 288_383 | 24 | 1434 | Domain | Fibronectin type-III 1 |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000428026 | + | 1 | 30 | 386_484 | 24 | 1434 | Domain | Fibronectin type-III 2 |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000428026 | + | 1 | 30 | 485_591 | 24 | 1434 | Domain | Fibronectin type-III 3 |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000428026 | + | 1 | 30 | 592_674 | 24 | 1434 | Domain | Fibronectin type-III 4 |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000428026 | + | 1 | 30 | 888_1144 | 24 | 1434 | Domain | Tyrosine-protein phosphatase 1 |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000460170 | + | 1 | 31 | 1176_1439 | 24 | 1441 | Domain | Tyrosine-protein phosphatase 2 |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000460170 | + | 1 | 31 | 190_275 | 24 | 1441 | Domain | Note=Ig-like C2-type |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000460170 | + | 1 | 31 | 25_188 | 24 | 1441 | Domain | MAM |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000460170 | + | 1 | 31 | 288_383 | 24 | 1441 | Domain | Fibronectin type-III 1 |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000460170 | + | 1 | 31 | 386_484 | 24 | 1441 | Domain | Fibronectin type-III 2 |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000460170 | + | 1 | 31 | 485_591 | 24 | 1441 | Domain | Fibronectin type-III 3 |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000460170 | + | 1 | 31 | 592_674 | 24 | 1441 | Domain | Fibronectin type-III 4 |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000460170 | + | 1 | 31 | 888_1144 | 24 | 1441 | Domain | Tyrosine-protein phosphatase 1 |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000345512 | + | 1 | 31 | 1085_1091 | 24 | 1447 | Region | Substrate binding |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000373779 | + | 1 | 30 | 1085_1091 | 24 | 1437 | Region | Substrate binding |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000428026 | + | 1 | 30 | 1085_1091 | 24 | 1434 | Region | Substrate binding |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000460170 | + | 1 | 31 | 1085_1091 | 24 | 1441 | Region | Substrate binding |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000345512 | + | 1 | 31 | 19_749 | 24 | 1447 | Topological domain | Extracellular |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000345512 | + | 1 | 31 | 771_1446 | 24 | 1447 | Topological domain | Cytoplasmic |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000373779 | + | 1 | 30 | 19_749 | 24 | 1437 | Topological domain | Extracellular |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000373779 | + | 1 | 30 | 771_1446 | 24 | 1437 | Topological domain | Cytoplasmic |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000428026 | + | 1 | 30 | 19_749 | 24 | 1434 | Topological domain | Extracellular |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000428026 | + | 1 | 30 | 771_1446 | 24 | 1434 | Topological domain | Cytoplasmic |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000460170 | + | 1 | 31 | 19_749 | 24 | 1441 | Topological domain | Extracellular |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000460170 | + | 1 | 31 | 771_1446 | 24 | 1441 | Topological domain | Cytoplasmic |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000345512 | + | 1 | 31 | 750_770 | 24 | 1447 | Transmembrane | Helical |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000373779 | + | 1 | 30 | 750_770 | 24 | 1437 | Transmembrane | Helical |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000428026 | + | 1 | 30 | 750_770 | 24 | 1434 | Transmembrane | Helical |
| Hgene | >PTPRU | chr1:29563229 | chr1:11345701 | ENST00000460170 | + | 1 | 31 | 750_770 | 24 | 1441 | Transmembrane | Helical |
| Tgene | UBIAD1 | chr1:29563229 | chr1:11345701 | ENST00000376810 | + | 0 | 2 | 134_154 | 176 | 339 | Transmembrane | Helical |
| Tgene | UBIAD1 | chr1:29563229 | chr1:11345701 | ENST00000376810 | + | 0 | 2 | 160_180 | 176 | 339 | Transmembrane | Helical |
| Tgene | UBIAD1 | chr1:29563229 | chr1:11345701 | ENST00000376810 | + | 0 | 2 | 83_103 | 176 | 339 | Transmembrane | Helical |
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FusionGeneSequence for PTPRU_UBIAD1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_PTPRU_ENST00000345512_chr1_29563229_+_UBIAD1_ENST00000376810_chr1_11345701_+_187aa MARAQALVLALTFQLCAPETETPAGIGFKYVALGDLIILITFGPLAVMFAYAIQVGSLAIFPLVYAIPLALSTEAILHSNNTRDMESDRE AGIVTLAILIGPTFSYILYNTLLFLPYLVFSILATHCTISLALPLLTIPMAFSLERQFRSQAFNKLPQRTAKLNLLLGLFYVFGIILAPA >In-frame_PTPRU_ENST00000373779_chr1_29563229_+_UBIAD1_ENST00000376810_chr1_11345701_+_187aa MARAQALVLALTFQLCAPETETPAGIGFKYVALGDLIILITFGPLAVMFAYAIQVGSLAIFPLVYAIPLALSTEAILHSNNTRDMESDRE AGIVTLAILIGPTFSYILYNTLLFLPYLVFSILATHCTISLALPLLTIPMAFSLERQFRSQAFNKLPQRTAKLNLLLGLFYVFGIILAPA >In-frame_PTPRU_ENST00000356870_chr1_29563229_+_UBIAD1_ENST00000376810_chr1_11345701_+_187aa MARAQALVLALTFQLCAPETETPAGIGFKYVALGDLIILITFGPLAVMFAYAIQVGSLAIFPLVYAIPLALSTEAILHSNNTRDMESDRE AGIVTLAILIGPTFSYILYNTLLFLPYLVFSILATHCTISLALPLLTIPMAFSLERQFRSQAFNKLPQRTAKLNLLLGLFYVFGIILAPA >In-frame_PTPRU_ENST00000323874_chr1_29563229_+_UBIAD1_ENST00000376810_chr1_11345701_+_187aa MARAQALVLALTFQLCAPETETPAGIGFKYVALGDLIILITFGPLAVMFAYAIQVGSLAIFPLVYAIPLALSTEAILHSNNTRDMESDRE AGIVTLAILIGPTFSYILYNTLLFLPYLVFSILATHCTISLALPLLTIPMAFSLERQFRSQAFNKLPQRTAKLNLLLGLFYVFGIILAPA >In-frame_PTPRU_ENST00000428026_chr1_29563229_+_UBIAD1_ENST00000376810_chr1_11345701_+_187aa MARAQALVLALTFQLCAPETETPAGIGFKYVALGDLIILITFGPLAVMFAYAIQVGSLAIFPLVYAIPLALSTEAILHSNNTRDMESDRE AGIVTLAILIGPTFSYILYNTLLFLPYLVFSILATHCTISLALPLLTIPMAFSLERQFRSQAFNKLPQRTAKLNLLLGLFYVFGIILAPA >In-frame_PTPRU_ENST00000460170_chr1_29563229_+_UBIAD1_ENST00000376810_chr1_11345701_+_187aa MARAQALVLALTFQLCAPETETPAGIGFKYVALGDLIILITFGPLAVMFAYAIQVGSLAIFPLVYAIPLALSTEAILHSNNTRDMESDRE AGIVTLAILIGPTFSYILYNTLLFLPYLVFSILATHCTISLALPLLTIPMAFSLERQFRSQAFNKLPQRTAKLNLLLGLFYVFGIILAPA |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_PTPRU_ENST00000345512_chr1_29563229_+_UBIAD1_ENST00000376810_chr1_11345701_+_561nt ATGGCCCGTGCCCAGGCGCTCGTGCTGGCACTCACCTTCCAGCTCTGCGCGCCGGAGACCGAGACTCCGGCAGGAATTGGATTCAAGTAC GTGGCTCTGGGAGACCTCATCATCCTCATCACTTTTGGCCCGCTGGCTGTGATGTTCGCCTACGCCATCCAGGTGGGGTCCCTGGCCATC TTCCCACTGGTCTATGCCATCCCCCTCGCCCTCAGCACCGAGGCCATTCTCCATTCCAACAACACCAGGGACATGGAGTCCGACCGGGAG GCTGGTATCGTCACGCTGGCCATCCTCATCGGCCCCACGTTCTCCTACATTCTCTACAACACACTGCTCTTCCTGCCCTACCTGGTCTTC AGCATCCTGGCCACACACTGCACCATCAGCCTGGCACTCCCCCTGCTTACCATTCCCATGGCCTTCTCCCTTGAGAGACAGTTTCGAAGC CAGGCCTTCAACAAACTGCCCCAGAGGACTGCCAAGCTCAACCTCCTGCTGGGACTTTTCTATGTCTTTGGCATCATTCTGGCACCAGCA >In-frame_PTPRU_ENST00000373779_chr1_29563229_+_UBIAD1_ENST00000376810_chr1_11345701_+_561nt ATGGCCCGTGCCCAGGCGCTCGTGCTGGCACTCACCTTCCAGCTCTGCGCGCCGGAGACCGAGACTCCGGCAGGAATTGGATTCAAGTAC GTGGCTCTGGGAGACCTCATCATCCTCATCACTTTTGGCCCGCTGGCTGTGATGTTCGCCTACGCCATCCAGGTGGGGTCCCTGGCCATC TTCCCACTGGTCTATGCCATCCCCCTCGCCCTCAGCACCGAGGCCATTCTCCATTCCAACAACACCAGGGACATGGAGTCCGACCGGGAG GCTGGTATCGTCACGCTGGCCATCCTCATCGGCCCCACGTTCTCCTACATTCTCTACAACACACTGCTCTTCCTGCCCTACCTGGTCTTC AGCATCCTGGCCACACACTGCACCATCAGCCTGGCACTCCCCCTGCTTACCATTCCCATGGCCTTCTCCCTTGAGAGACAGTTTCGAAGC CAGGCCTTCAACAAACTGCCCCAGAGGACTGCCAAGCTCAACCTCCTGCTGGGACTTTTCTATGTCTTTGGCATCATTCTGGCACCAGCA >In-frame_PTPRU_ENST00000356870_chr1_29563229_+_UBIAD1_ENST00000376810_chr1_11345701_+_561nt ATGGCCCGTGCCCAGGCGCTCGTGCTGGCACTCACCTTCCAGCTCTGCGCGCCGGAGACCGAGACTCCGGCAGGAATTGGATTCAAGTAC GTGGCTCTGGGAGACCTCATCATCCTCATCACTTTTGGCCCGCTGGCTGTGATGTTCGCCTACGCCATCCAGGTGGGGTCCCTGGCCATC TTCCCACTGGTCTATGCCATCCCCCTCGCCCTCAGCACCGAGGCCATTCTCCATTCCAACAACACCAGGGACATGGAGTCCGACCGGGAG GCTGGTATCGTCACGCTGGCCATCCTCATCGGCCCCACGTTCTCCTACATTCTCTACAACACACTGCTCTTCCTGCCCTACCTGGTCTTC AGCATCCTGGCCACACACTGCACCATCAGCCTGGCACTCCCCCTGCTTACCATTCCCATGGCCTTCTCCCTTGAGAGACAGTTTCGAAGC CAGGCCTTCAACAAACTGCCCCAGAGGACTGCCAAGCTCAACCTCCTGCTGGGACTTTTCTATGTCTTTGGCATCATTCTGGCACCAGCA >In-frame_PTPRU_ENST00000323874_chr1_29563229_+_UBIAD1_ENST00000376810_chr1_11345701_+_561nt ATGGCCCGTGCCCAGGCGCTCGTGCTGGCACTCACCTTCCAGCTCTGCGCGCCGGAGACCGAGACTCCGGCAGGAATTGGATTCAAGTAC GTGGCTCTGGGAGACCTCATCATCCTCATCACTTTTGGCCCGCTGGCTGTGATGTTCGCCTACGCCATCCAGGTGGGGTCCCTGGCCATC TTCCCACTGGTCTATGCCATCCCCCTCGCCCTCAGCACCGAGGCCATTCTCCATTCCAACAACACCAGGGACATGGAGTCCGACCGGGAG GCTGGTATCGTCACGCTGGCCATCCTCATCGGCCCCACGTTCTCCTACATTCTCTACAACACACTGCTCTTCCTGCCCTACCTGGTCTTC AGCATCCTGGCCACACACTGCACCATCAGCCTGGCACTCCCCCTGCTTACCATTCCCATGGCCTTCTCCCTTGAGAGACAGTTTCGAAGC CAGGCCTTCAACAAACTGCCCCAGAGGACTGCCAAGCTCAACCTCCTGCTGGGACTTTTCTATGTCTTTGGCATCATTCTGGCACCAGCA >In-frame_PTPRU_ENST00000428026_chr1_29563229_+_UBIAD1_ENST00000376810_chr1_11345701_+_561nt ATGGCCCGTGCCCAGGCGCTCGTGCTGGCACTCACCTTCCAGCTCTGCGCGCCGGAGACCGAGACTCCGGCAGGAATTGGATTCAAGTAC GTGGCTCTGGGAGACCTCATCATCCTCATCACTTTTGGCCCGCTGGCTGTGATGTTCGCCTACGCCATCCAGGTGGGGTCCCTGGCCATC TTCCCACTGGTCTATGCCATCCCCCTCGCCCTCAGCACCGAGGCCATTCTCCATTCCAACAACACCAGGGACATGGAGTCCGACCGGGAG GCTGGTATCGTCACGCTGGCCATCCTCATCGGCCCCACGTTCTCCTACATTCTCTACAACACACTGCTCTTCCTGCCCTACCTGGTCTTC AGCATCCTGGCCACACACTGCACCATCAGCCTGGCACTCCCCCTGCTTACCATTCCCATGGCCTTCTCCCTTGAGAGACAGTTTCGAAGC CAGGCCTTCAACAAACTGCCCCAGAGGACTGCCAAGCTCAACCTCCTGCTGGGACTTTTCTATGTCTTTGGCATCATTCTGGCACCAGCA >In-frame_PTPRU_ENST00000460170_chr1_29563229_+_UBIAD1_ENST00000376810_chr1_11345701_+_561nt ATGGCCCGTGCCCAGGCGCTCGTGCTGGCACTCACCTTCCAGCTCTGCGCGCCGGAGACCGAGACTCCGGCAGGAATTGGATTCAAGTAC GTGGCTCTGGGAGACCTCATCATCCTCATCACTTTTGGCCCGCTGGCTGTGATGTTCGCCTACGCCATCCAGGTGGGGTCCCTGGCCATC TTCCCACTGGTCTATGCCATCCCCCTCGCCCTCAGCACCGAGGCCATTCTCCATTCCAACAACACCAGGGACATGGAGTCCGACCGGGAG GCTGGTATCGTCACGCTGGCCATCCTCATCGGCCCCACGTTCTCCTACATTCTCTACAACACACTGCTCTTCCTGCCCTACCTGGTCTTC AGCATCCTGGCCACACACTGCACCATCAGCCTGGCACTCCCCCTGCTTACCATTCCCATGGCCTTCTCCCTTGAGAGACAGTTTCGAAGC CAGGCCTTCAACAAACTGCCCCAGAGGACTGCCAAGCTCAACCTCCTGCTGGGACTTTTCTATGTCTTTGGCATCATTCTGGCACCAGCA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_PTPRU_ENST00000345512_chr1_29563229_+_UBIAD1_ENST00000376810_chr1_11345701_+_2993nt GGCGCCAGTCCCGCTCCGCGCCGCGCCGCTCCGCTCCGGCTCGGGCTCCGGCTCGCCTCGGGCTGGGCTCGGGCTCCGGGGGCGGCGTCC CCCGCGCCGGGCCCCGGGACGGGCGGCGACGCTCCAACCATGGCCCGTGCCCAGGCGCTCGTGCTGGCACTCACCTTCCAGCTCTGCGCG CCGGAGACCGAGACTCCGGCAGGAATTGGATTCAAGTACGTGGCTCTGGGAGACCTCATCATCCTCATCACTTTTGGCCCGCTGGCTGTG ATGTTCGCCTACGCCATCCAGGTGGGGTCCCTGGCCATCTTCCCACTGGTCTATGCCATCCCCCTCGCCCTCAGCACCGAGGCCATTCTC CATTCCAACAACACCAGGGACATGGAGTCCGACCGGGAGGCTGGTATCGTCACGCTGGCCATCCTCATCGGCCCCACGTTCTCCTACATT CTCTACAACACACTGCTCTTCCTGCCCTACCTGGTCTTCAGCATCCTGGCCACACACTGCACCATCAGCCTGGCACTCCCCCTGCTTACC ATTCCCATGGCCTTCTCCCTTGAGAGACAGTTTCGAAGCCAGGCCTTCAACAAACTGCCCCAGAGGACTGCCAAGCTCAACCTCCTGCTG GGACTTTTCTATGTCTTTGGCATCATTCTGGCACCAGCAGGCAGTCTGCCCAAAATTTAAGGGGACAAGTAGCTCCCCCCACGACATGTC TCCCTTTCTTAGAATATATTAAAGTCAGAGTCTCTGAGGAAGGAATGTGATTTGGCAGTCAGGGTACTAAGCATGGGTGGGAACTCCTGC CTTATAAAAATTGTTTTTGTGTTCTTAAAGATAATATGTTGTTTTTCTGTTTTTTGTTTTTTCCATTTTATGGGGAATTTAAAAACCATT CTTGTATCAGAAGGTGAATTAGGCGCATGGTCTTTGTTTTATTAATAATTTCCACTAGAGGGTGTTCTCAGGTCACTTTGCAGTGAAGTG GACTTAGTTCCTCCTTGTTCTGTACAAAATGTCTCCAGACTTTGTAAAGGAGCTGCCCAGTTTGGCCTCCTGTCCCGAAAAGACCCTAAT AACTAGGCAGAGTGTTGTCCTGCTTTCTTCGTCTCGTAGGATGTGCTATGATTGGTGCCAGGCCTCACTAACACAGGGGCTACCTGTCTC TTATTCTCAGCACCTGTGTCCTGAGATACGCTGCCTGAGACAGAGAGAGTCCCTCATTAACAGCCTGTGTGGCTGTCAGCTTTTTGCCTA AATTGTGATTCAGATGCTTTTGTTCTCTCTCCTTTCACTTATTGCCACAGTTGAGGAAAAGTGTCAGATTACCCTGCAGCAAGACAAGCC AAGGACTGGGAGGGAAAAAAAAACCACTCTGGAGGCAACTGAGAAAATCACTGCTTTTGGATAGGAATCAGTAGGGTGGCTGTTTTCCCT TTGTTGAATCTACTAGAGTGACAGGAAGGACTCCCAGCCCTTTCAGTAACTATCAGGAGCCCTGAAACGGTAGAGGCACTGCCATCCTTG TGGGATACTCAAAGCCCACAGGGCTTTTCCCTCCCTATTGCATCTTCTGATGCTCCCCACACCTACCCTCCACCTCTCCACCTCTGTGGT GTTCCCATTTGTGTGTTTCCCATCTGTGGAGCCAGACTGAGCAATAGCTTAGCAGCGAGTCAGGGACAGCTGCCACTTTCCACAGAGCCA CAGGATGGGCAGAGCAGGGACCCAGGGAATGAATAGCCAGTGGACAAACAGTCTTGAGCTCTGTTCAGCCAGAGTGATGGGCCCTGCCAG TTAAGGGGCTGTGTCTTCATCCTTGAAGACAGATGTGCAATATTGACCCTGCCTCTCCCCAGGGCTTTGTGGAAAGATAGTTGAGGGCTT TAGTGAGATCACACTCAGAGTGGGGCAATTCCAGCATTTATCCTGGCTGCGTTTCATTGCATTGTCTGTGAAGTATAATTTCTGGGCCAG AATTGCTCAGTTGCATTTGATCCAGGACTATAGATTGGAAATGGGTCATCATTGTTTTCTGTTGTGATTATAGCCATTCTAGTAGGCGTT TAAGGTCATGGCCTGCAGAAAATGATGTAAGAACTAGTTCTTAATCTTTCAGATCAAGCTAATGATGATATGGAACCTTGAGTTCGAATT GATTGGTTTACTTGGAAAAAAACATGTTTGAAAATTGCAAAAGTTCCGCCGGGCGCGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGA GGCCGAGACGGGCGGATCACGAGGTCAGGAGATCGAGACCATCTTGGCTAACACGGTGAAACCCCGTTTCTACTAAAAATACAAAAAATT AGCCAGGCGTGTTGGCGGGCGCCTGTAGTCCCAGCTACCTGGGCGGCTGAGGCAGGAGCATGGCGTGAACCCAGGAGGCGGAGCTTGCAG TGAGCTGAGATCATGCCACTGCACTCCAACCTGGGGGACACAGCAAGACTCCGTCTCAAAAAAAAAAAAAGAAAAAGAAAATTGCAAAAG TTCCTCTAAAGTTAAATCAAAGGTGGTTTGTCTAGCAGAGAGCCAGAATCTTCTAATAGTGGGCAGAGCCCAGAGACAAGGGGAAGAAAG ATGACCTTCTCCCCAGTCCTTCCCAGCACCATTTTTGTTTCACACCAGGCTTGTGGCATTTTGGTGCTCACAGGGGTTTTGCCTTCTGAC CTCTCCTTGGAGTAGGCCATTCTCATGCAGGGCTCACCCTGAGGCAGGAGGACCAAGGGCTCCCTGCGTCCACGGACCACGTATGCCTTG GTGGTCACTCCCATCGGGGCTATCAGTTCTGCACTGTGCCCTGGTGCGGATTTTAATGCATATTTTTATATATAAATGTTCCCAAAGGCC AAATTTGTTGCCAGGTTTTATACGCAGGTCACCATAATTTGTATTATGTTCCCTGAGTCAATGAAGGTTTTCTTTAGACTTCTTAATTAA >In-frame_PTPRU_ENST00000373779_chr1_29563229_+_UBIAD1_ENST00000376810_chr1_11345701_+_2993nt GGCGCCAGTCCCGCTCCGCGCCGCGCCGCTCCGCTCCGGCTCGGGCTCCGGCTCGCCTCGGGCTGGGCTCGGGCTCCGGGGGCGGCGTCC CCCGCGCCGGGCCCCGGGACGGGCGGCGACGCTCCAACCATGGCCCGTGCCCAGGCGCTCGTGCTGGCACTCACCTTCCAGCTCTGCGCG CCGGAGACCGAGACTCCGGCAGGAATTGGATTCAAGTACGTGGCTCTGGGAGACCTCATCATCCTCATCACTTTTGGCCCGCTGGCTGTG ATGTTCGCCTACGCCATCCAGGTGGGGTCCCTGGCCATCTTCCCACTGGTCTATGCCATCCCCCTCGCCCTCAGCACCGAGGCCATTCTC CATTCCAACAACACCAGGGACATGGAGTCCGACCGGGAGGCTGGTATCGTCACGCTGGCCATCCTCATCGGCCCCACGTTCTCCTACATT CTCTACAACACACTGCTCTTCCTGCCCTACCTGGTCTTCAGCATCCTGGCCACACACTGCACCATCAGCCTGGCACTCCCCCTGCTTACC ATTCCCATGGCCTTCTCCCTTGAGAGACAGTTTCGAAGCCAGGCCTTCAACAAACTGCCCCAGAGGACTGCCAAGCTCAACCTCCTGCTG GGACTTTTCTATGTCTTTGGCATCATTCTGGCACCAGCAGGCAGTCTGCCCAAAATTTAAGGGGACAAGTAGCTCCCCCCACGACATGTC TCCCTTTCTTAGAATATATTAAAGTCAGAGTCTCTGAGGAAGGAATGTGATTTGGCAGTCAGGGTACTAAGCATGGGTGGGAACTCCTGC CTTATAAAAATTGTTTTTGTGTTCTTAAAGATAATATGTTGTTTTTCTGTTTTTTGTTTTTTCCATTTTATGGGGAATTTAAAAACCATT CTTGTATCAGAAGGTGAATTAGGCGCATGGTCTTTGTTTTATTAATAATTTCCACTAGAGGGTGTTCTCAGGTCACTTTGCAGTGAAGTG GACTTAGTTCCTCCTTGTTCTGTACAAAATGTCTCCAGACTTTGTAAAGGAGCTGCCCAGTTTGGCCTCCTGTCCCGAAAAGACCCTAAT AACTAGGCAGAGTGTTGTCCTGCTTTCTTCGTCTCGTAGGATGTGCTATGATTGGTGCCAGGCCTCACTAACACAGGGGCTACCTGTCTC TTATTCTCAGCACCTGTGTCCTGAGATACGCTGCCTGAGACAGAGAGAGTCCCTCATTAACAGCCTGTGTGGCTGTCAGCTTTTTGCCTA AATTGTGATTCAGATGCTTTTGTTCTCTCTCCTTTCACTTATTGCCACAGTTGAGGAAAAGTGTCAGATTACCCTGCAGCAAGACAAGCC AAGGACTGGGAGGGAAAAAAAAACCACTCTGGAGGCAACTGAGAAAATCACTGCTTTTGGATAGGAATCAGTAGGGTGGCTGTTTTCCCT TTGTTGAATCTACTAGAGTGACAGGAAGGACTCCCAGCCCTTTCAGTAACTATCAGGAGCCCTGAAACGGTAGAGGCACTGCCATCCTTG TGGGATACTCAAAGCCCACAGGGCTTTTCCCTCCCTATTGCATCTTCTGATGCTCCCCACACCTACCCTCCACCTCTCCACCTCTGTGGT GTTCCCATTTGTGTGTTTCCCATCTGTGGAGCCAGACTGAGCAATAGCTTAGCAGCGAGTCAGGGACAGCTGCCACTTTCCACAGAGCCA CAGGATGGGCAGAGCAGGGACCCAGGGAATGAATAGCCAGTGGACAAACAGTCTTGAGCTCTGTTCAGCCAGAGTGATGGGCCCTGCCAG TTAAGGGGCTGTGTCTTCATCCTTGAAGACAGATGTGCAATATTGACCCTGCCTCTCCCCAGGGCTTTGTGGAAAGATAGTTGAGGGCTT TAGTGAGATCACACTCAGAGTGGGGCAATTCCAGCATTTATCCTGGCTGCGTTTCATTGCATTGTCTGTGAAGTATAATTTCTGGGCCAG AATTGCTCAGTTGCATTTGATCCAGGACTATAGATTGGAAATGGGTCATCATTGTTTTCTGTTGTGATTATAGCCATTCTAGTAGGCGTT TAAGGTCATGGCCTGCAGAAAATGATGTAAGAACTAGTTCTTAATCTTTCAGATCAAGCTAATGATGATATGGAACCTTGAGTTCGAATT GATTGGTTTACTTGGAAAAAAACATGTTTGAAAATTGCAAAAGTTCCGCCGGGCGCGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGA GGCCGAGACGGGCGGATCACGAGGTCAGGAGATCGAGACCATCTTGGCTAACACGGTGAAACCCCGTTTCTACTAAAAATACAAAAAATT AGCCAGGCGTGTTGGCGGGCGCCTGTAGTCCCAGCTACCTGGGCGGCTGAGGCAGGAGCATGGCGTGAACCCAGGAGGCGGAGCTTGCAG TGAGCTGAGATCATGCCACTGCACTCCAACCTGGGGGACACAGCAAGACTCCGTCTCAAAAAAAAAAAAAGAAAAAGAAAATTGCAAAAG TTCCTCTAAAGTTAAATCAAAGGTGGTTTGTCTAGCAGAGAGCCAGAATCTTCTAATAGTGGGCAGAGCCCAGAGACAAGGGGAAGAAAG ATGACCTTCTCCCCAGTCCTTCCCAGCACCATTTTTGTTTCACACCAGGCTTGTGGCATTTTGGTGCTCACAGGGGTTTTGCCTTCTGAC CTCTCCTTGGAGTAGGCCATTCTCATGCAGGGCTCACCCTGAGGCAGGAGGACCAAGGGCTCCCTGCGTCCACGGACCACGTATGCCTTG GTGGTCACTCCCATCGGGGCTATCAGTTCTGCACTGTGCCCTGGTGCGGATTTTAATGCATATTTTTATATATAAATGTTCCCAAAGGCC AAATTTGTTGCCAGGTTTTATACGCAGGTCACCATAATTTGTATTATGTTCCCTGAGTCAATGAAGGTTTTCTTTAGACTTCTTAATTAA >In-frame_PTPRU_ENST00000356870_chr1_29563229_+_UBIAD1_ENST00000376810_chr1_11345701_+_2974nt GCCGCGCCGCTCCGCTCCGGCTCGGGCTCCGGCTCGCCTCGGGCTGGGCTCGGGCTCCGGGGGCGGCGTCCCCCGCGCCGGGCCCCGGGA CGGGCGGCGACGCTCCAACCATGGCCCGTGCCCAGGCGCTCGTGCTGGCACTCACCTTCCAGCTCTGCGCGCCGGAGACCGAGACTCCGG CAGGAATTGGATTCAAGTACGTGGCTCTGGGAGACCTCATCATCCTCATCACTTTTGGCCCGCTGGCTGTGATGTTCGCCTACGCCATCC AGGTGGGGTCCCTGGCCATCTTCCCACTGGTCTATGCCATCCCCCTCGCCCTCAGCACCGAGGCCATTCTCCATTCCAACAACACCAGGG ACATGGAGTCCGACCGGGAGGCTGGTATCGTCACGCTGGCCATCCTCATCGGCCCCACGTTCTCCTACATTCTCTACAACACACTGCTCT TCCTGCCCTACCTGGTCTTCAGCATCCTGGCCACACACTGCACCATCAGCCTGGCACTCCCCCTGCTTACCATTCCCATGGCCTTCTCCC TTGAGAGACAGTTTCGAAGCCAGGCCTTCAACAAACTGCCCCAGAGGACTGCCAAGCTCAACCTCCTGCTGGGACTTTTCTATGTCTTTG GCATCATTCTGGCACCAGCAGGCAGTCTGCCCAAAATTTAAGGGGACAAGTAGCTCCCCCCACGACATGTCTCCCTTTCTTAGAATATAT TAAAGTCAGAGTCTCTGAGGAAGGAATGTGATTTGGCAGTCAGGGTACTAAGCATGGGTGGGAACTCCTGCCTTATAAAAATTGTTTTTG TGTTCTTAAAGATAATATGTTGTTTTTCTGTTTTTTGTTTTTTCCATTTTATGGGGAATTTAAAAACCATTCTTGTATCAGAAGGTGAAT TAGGCGCATGGTCTTTGTTTTATTAATAATTTCCACTAGAGGGTGTTCTCAGGTCACTTTGCAGTGAAGTGGACTTAGTTCCTCCTTGTT CTGTACAAAATGTCTCCAGACTTTGTAAAGGAGCTGCCCAGTTTGGCCTCCTGTCCCGAAAAGACCCTAATAACTAGGCAGAGTGTTGTC CTGCTTTCTTCGTCTCGTAGGATGTGCTATGATTGGTGCCAGGCCTCACTAACACAGGGGCTACCTGTCTCTTATTCTCAGCACCTGTGT CCTGAGATACGCTGCCTGAGACAGAGAGAGTCCCTCATTAACAGCCTGTGTGGCTGTCAGCTTTTTGCCTAAATTGTGATTCAGATGCTT TTGTTCTCTCTCCTTTCACTTATTGCCACAGTTGAGGAAAAGTGTCAGATTACCCTGCAGCAAGACAAGCCAAGGACTGGGAGGGAAAAA AAAACCACTCTGGAGGCAACTGAGAAAATCACTGCTTTTGGATAGGAATCAGTAGGGTGGCTGTTTTCCCTTTGTTGAATCTACTAGAGT GACAGGAAGGACTCCCAGCCCTTTCAGTAACTATCAGGAGCCCTGAAACGGTAGAGGCACTGCCATCCTTGTGGGATACTCAAAGCCCAC AGGGCTTTTCCCTCCCTATTGCATCTTCTGATGCTCCCCACACCTACCCTCCACCTCTCCACCTCTGTGGTGTTCCCATTTGTGTGTTTC CCATCTGTGGAGCCAGACTGAGCAATAGCTTAGCAGCGAGTCAGGGACAGCTGCCACTTTCCACAGAGCCACAGGATGGGCAGAGCAGGG ACCCAGGGAATGAATAGCCAGTGGACAAACAGTCTTGAGCTCTGTTCAGCCAGAGTGATGGGCCCTGCCAGTTAAGGGGCTGTGTCTTCA TCCTTGAAGACAGATGTGCAATATTGACCCTGCCTCTCCCCAGGGCTTTGTGGAAAGATAGTTGAGGGCTTTAGTGAGATCACACTCAGA GTGGGGCAATTCCAGCATTTATCCTGGCTGCGTTTCATTGCATTGTCTGTGAAGTATAATTTCTGGGCCAGAATTGCTCAGTTGCATTTG ATCCAGGACTATAGATTGGAAATGGGTCATCATTGTTTTCTGTTGTGATTATAGCCATTCTAGTAGGCGTTTAAGGTCATGGCCTGCAGA AAATGATGTAAGAACTAGTTCTTAATCTTTCAGATCAAGCTAATGATGATATGGAACCTTGAGTTCGAATTGATTGGTTTACTTGGAAAA AAACATGTTTGAAAATTGCAAAAGTTCCGCCGGGCGCGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGACGGGCGGATCA CGAGGTCAGGAGATCGAGACCATCTTGGCTAACACGGTGAAACCCCGTTTCTACTAAAAATACAAAAAATTAGCCAGGCGTGTTGGCGGG CGCCTGTAGTCCCAGCTACCTGGGCGGCTGAGGCAGGAGCATGGCGTGAACCCAGGAGGCGGAGCTTGCAGTGAGCTGAGATCATGCCAC TGCACTCCAACCTGGGGGACACAGCAAGACTCCGTCTCAAAAAAAAAAAAAGAAAAAGAAAATTGCAAAAGTTCCTCTAAAGTTAAATCA AAGGTGGTTTGTCTAGCAGAGAGCCAGAATCTTCTAATAGTGGGCAGAGCCCAGAGACAAGGGGAAGAAAGATGACCTTCTCCCCAGTCC TTCCCAGCACCATTTTTGTTTCACACCAGGCTTGTGGCATTTTGGTGCTCACAGGGGTTTTGCCTTCTGACCTCTCCTTGGAGTAGGCCA TTCTCATGCAGGGCTCACCCTGAGGCAGGAGGACCAAGGGCTCCCTGCGTCCACGGACCACGTATGCCTTGGTGGTCACTCCCATCGGGG CTATCAGTTCTGCACTGTGCCCTGGTGCGGATTTTAATGCATATTTTTATATATAAATGTTCCCAAAGGCCAAATTTGTTGCCAGGTTTT ATACGCAGGTCACCATAATTTGTATTATGTTCCCTGAGTCAATGAAGGTTTTCTTTAGACTTCTTAATTAAAAAGAGAAGAAAGAAAATG >In-frame_PTPRU_ENST00000323874_chr1_29563229_+_UBIAD1_ENST00000376810_chr1_11345701_+_2974nt GCCGCGCCGCTCCGCTCCGGCTCGGGCTCCGGCTCGCCTCGGGCTGGGCTCGGGCTCCGGGGGCGGCGTCCCCCGCGCCGGGCCCCGGGA CGGGCGGCGACGCTCCAACCATGGCCCGTGCCCAGGCGCTCGTGCTGGCACTCACCTTCCAGCTCTGCGCGCCGGAGACCGAGACTCCGG CAGGAATTGGATTCAAGTACGTGGCTCTGGGAGACCTCATCATCCTCATCACTTTTGGCCCGCTGGCTGTGATGTTCGCCTACGCCATCC AGGTGGGGTCCCTGGCCATCTTCCCACTGGTCTATGCCATCCCCCTCGCCCTCAGCACCGAGGCCATTCTCCATTCCAACAACACCAGGG ACATGGAGTCCGACCGGGAGGCTGGTATCGTCACGCTGGCCATCCTCATCGGCCCCACGTTCTCCTACATTCTCTACAACACACTGCTCT TCCTGCCCTACCTGGTCTTCAGCATCCTGGCCACACACTGCACCATCAGCCTGGCACTCCCCCTGCTTACCATTCCCATGGCCTTCTCCC TTGAGAGACAGTTTCGAAGCCAGGCCTTCAACAAACTGCCCCAGAGGACTGCCAAGCTCAACCTCCTGCTGGGACTTTTCTATGTCTTTG GCATCATTCTGGCACCAGCAGGCAGTCTGCCCAAAATTTAAGGGGACAAGTAGCTCCCCCCACGACATGTCTCCCTTTCTTAGAATATAT TAAAGTCAGAGTCTCTGAGGAAGGAATGTGATTTGGCAGTCAGGGTACTAAGCATGGGTGGGAACTCCTGCCTTATAAAAATTGTTTTTG TGTTCTTAAAGATAATATGTTGTTTTTCTGTTTTTTGTTTTTTCCATTTTATGGGGAATTTAAAAACCATTCTTGTATCAGAAGGTGAAT TAGGCGCATGGTCTTTGTTTTATTAATAATTTCCACTAGAGGGTGTTCTCAGGTCACTTTGCAGTGAAGTGGACTTAGTTCCTCCTTGTT CTGTACAAAATGTCTCCAGACTTTGTAAAGGAGCTGCCCAGTTTGGCCTCCTGTCCCGAAAAGACCCTAATAACTAGGCAGAGTGTTGTC CTGCTTTCTTCGTCTCGTAGGATGTGCTATGATTGGTGCCAGGCCTCACTAACACAGGGGCTACCTGTCTCTTATTCTCAGCACCTGTGT CCTGAGATACGCTGCCTGAGACAGAGAGAGTCCCTCATTAACAGCCTGTGTGGCTGTCAGCTTTTTGCCTAAATTGTGATTCAGATGCTT TTGTTCTCTCTCCTTTCACTTATTGCCACAGTTGAGGAAAAGTGTCAGATTACCCTGCAGCAAGACAAGCCAAGGACTGGGAGGGAAAAA AAAACCACTCTGGAGGCAACTGAGAAAATCACTGCTTTTGGATAGGAATCAGTAGGGTGGCTGTTTTCCCTTTGTTGAATCTACTAGAGT GACAGGAAGGACTCCCAGCCCTTTCAGTAACTATCAGGAGCCCTGAAACGGTAGAGGCACTGCCATCCTTGTGGGATACTCAAAGCCCAC AGGGCTTTTCCCTCCCTATTGCATCTTCTGATGCTCCCCACACCTACCCTCCACCTCTCCACCTCTGTGGTGTTCCCATTTGTGTGTTTC CCATCTGTGGAGCCAGACTGAGCAATAGCTTAGCAGCGAGTCAGGGACAGCTGCCACTTTCCACAGAGCCACAGGATGGGCAGAGCAGGG ACCCAGGGAATGAATAGCCAGTGGACAAACAGTCTTGAGCTCTGTTCAGCCAGAGTGATGGGCCCTGCCAGTTAAGGGGCTGTGTCTTCA TCCTTGAAGACAGATGTGCAATATTGACCCTGCCTCTCCCCAGGGCTTTGTGGAAAGATAGTTGAGGGCTTTAGTGAGATCACACTCAGA GTGGGGCAATTCCAGCATTTATCCTGGCTGCGTTTCATTGCATTGTCTGTGAAGTATAATTTCTGGGCCAGAATTGCTCAGTTGCATTTG ATCCAGGACTATAGATTGGAAATGGGTCATCATTGTTTTCTGTTGTGATTATAGCCATTCTAGTAGGCGTTTAAGGTCATGGCCTGCAGA AAATGATGTAAGAACTAGTTCTTAATCTTTCAGATCAAGCTAATGATGATATGGAACCTTGAGTTCGAATTGATTGGTTTACTTGGAAAA AAACATGTTTGAAAATTGCAAAAGTTCCGCCGGGCGCGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGACGGGCGGATCA CGAGGTCAGGAGATCGAGACCATCTTGGCTAACACGGTGAAACCCCGTTTCTACTAAAAATACAAAAAATTAGCCAGGCGTGTTGGCGGG CGCCTGTAGTCCCAGCTACCTGGGCGGCTGAGGCAGGAGCATGGCGTGAACCCAGGAGGCGGAGCTTGCAGTGAGCTGAGATCATGCCAC TGCACTCCAACCTGGGGGACACAGCAAGACTCCGTCTCAAAAAAAAAAAAAGAAAAAGAAAATTGCAAAAGTTCCTCTAAAGTTAAATCA AAGGTGGTTTGTCTAGCAGAGAGCCAGAATCTTCTAATAGTGGGCAGAGCCCAGAGACAAGGGGAAGAAAGATGACCTTCTCCCCAGTCC TTCCCAGCACCATTTTTGTTTCACACCAGGCTTGTGGCATTTTGGTGCTCACAGGGGTTTTGCCTTCTGACCTCTCCTTGGAGTAGGCCA TTCTCATGCAGGGCTCACCCTGAGGCAGGAGGACCAAGGGCTCCCTGCGTCCACGGACCACGTATGCCTTGGTGGTCACTCCCATCGGGG CTATCAGTTCTGCACTGTGCCCTGGTGCGGATTTTAATGCATATTTTTATATATAAATGTTCCCAAAGGCCAAATTTGTTGCCAGGTTTT ATACGCAGGTCACCATAATTTGTATTATGTTCCCTGAGTCAATGAAGGTTTTCTTTAGACTTCTTAATTAAAAAGAGAAGAAAGAAAATG >In-frame_PTPRU_ENST00000428026_chr1_29563229_+_UBIAD1_ENST00000376810_chr1_11345701_+_2960nt CTCCGGCTCGGGCTCCGGCTCGCCTCGGGCTGGGCTCGGGCTCCGGGGGCGGCGTCCCCCGCGCCGGGCCCCGGGACGGGCGGCGACGCT CCAACCATGGCCCGTGCCCAGGCGCTCGTGCTGGCACTCACCTTCCAGCTCTGCGCGCCGGAGACCGAGACTCCGGCAGGAATTGGATTC AAGTACGTGGCTCTGGGAGACCTCATCATCCTCATCACTTTTGGCCCGCTGGCTGTGATGTTCGCCTACGCCATCCAGGTGGGGTCCCTG GCCATCTTCCCACTGGTCTATGCCATCCCCCTCGCCCTCAGCACCGAGGCCATTCTCCATTCCAACAACACCAGGGACATGGAGTCCGAC CGGGAGGCTGGTATCGTCACGCTGGCCATCCTCATCGGCCCCACGTTCTCCTACATTCTCTACAACACACTGCTCTTCCTGCCCTACCTG GTCTTCAGCATCCTGGCCACACACTGCACCATCAGCCTGGCACTCCCCCTGCTTACCATTCCCATGGCCTTCTCCCTTGAGAGACAGTTT CGAAGCCAGGCCTTCAACAAACTGCCCCAGAGGACTGCCAAGCTCAACCTCCTGCTGGGACTTTTCTATGTCTTTGGCATCATTCTGGCA CCAGCAGGCAGTCTGCCCAAAATTTAAGGGGACAAGTAGCTCCCCCCACGACATGTCTCCCTTTCTTAGAATATATTAAAGTCAGAGTCT CTGAGGAAGGAATGTGATTTGGCAGTCAGGGTACTAAGCATGGGTGGGAACTCCTGCCTTATAAAAATTGTTTTTGTGTTCTTAAAGATA ATATGTTGTTTTTCTGTTTTTTGTTTTTTCCATTTTATGGGGAATTTAAAAACCATTCTTGTATCAGAAGGTGAATTAGGCGCATGGTCT TTGTTTTATTAATAATTTCCACTAGAGGGTGTTCTCAGGTCACTTTGCAGTGAAGTGGACTTAGTTCCTCCTTGTTCTGTACAAAATGTC TCCAGACTTTGTAAAGGAGCTGCCCAGTTTGGCCTCCTGTCCCGAAAAGACCCTAATAACTAGGCAGAGTGTTGTCCTGCTTTCTTCGTC TCGTAGGATGTGCTATGATTGGTGCCAGGCCTCACTAACACAGGGGCTACCTGTCTCTTATTCTCAGCACCTGTGTCCTGAGATACGCTG CCTGAGACAGAGAGAGTCCCTCATTAACAGCCTGTGTGGCTGTCAGCTTTTTGCCTAAATTGTGATTCAGATGCTTTTGTTCTCTCTCCT TTCACTTATTGCCACAGTTGAGGAAAAGTGTCAGATTACCCTGCAGCAAGACAAGCCAAGGACTGGGAGGGAAAAAAAAACCACTCTGGA GGCAACTGAGAAAATCACTGCTTTTGGATAGGAATCAGTAGGGTGGCTGTTTTCCCTTTGTTGAATCTACTAGAGTGACAGGAAGGACTC CCAGCCCTTTCAGTAACTATCAGGAGCCCTGAAACGGTAGAGGCACTGCCATCCTTGTGGGATACTCAAAGCCCACAGGGCTTTTCCCTC CCTATTGCATCTTCTGATGCTCCCCACACCTACCCTCCACCTCTCCACCTCTGTGGTGTTCCCATTTGTGTGTTTCCCATCTGTGGAGCC AGACTGAGCAATAGCTTAGCAGCGAGTCAGGGACAGCTGCCACTTTCCACAGAGCCACAGGATGGGCAGAGCAGGGACCCAGGGAATGAA TAGCCAGTGGACAAACAGTCTTGAGCTCTGTTCAGCCAGAGTGATGGGCCCTGCCAGTTAAGGGGCTGTGTCTTCATCCTTGAAGACAGA TGTGCAATATTGACCCTGCCTCTCCCCAGGGCTTTGTGGAAAGATAGTTGAGGGCTTTAGTGAGATCACACTCAGAGTGGGGCAATTCCA GCATTTATCCTGGCTGCGTTTCATTGCATTGTCTGTGAAGTATAATTTCTGGGCCAGAATTGCTCAGTTGCATTTGATCCAGGACTATAG ATTGGAAATGGGTCATCATTGTTTTCTGTTGTGATTATAGCCATTCTAGTAGGCGTTTAAGGTCATGGCCTGCAGAAAATGATGTAAGAA CTAGTTCTTAATCTTTCAGATCAAGCTAATGATGATATGGAACCTTGAGTTCGAATTGATTGGTTTACTTGGAAAAAAACATGTTTGAAA ATTGCAAAAGTTCCGCCGGGCGCGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGACGGGCGGATCACGAGGTCAGGAGAT CGAGACCATCTTGGCTAACACGGTGAAACCCCGTTTCTACTAAAAATACAAAAAATTAGCCAGGCGTGTTGGCGGGCGCCTGTAGTCCCA GCTACCTGGGCGGCTGAGGCAGGAGCATGGCGTGAACCCAGGAGGCGGAGCTTGCAGTGAGCTGAGATCATGCCACTGCACTCCAACCTG GGGGACACAGCAAGACTCCGTCTCAAAAAAAAAAAAAGAAAAAGAAAATTGCAAAAGTTCCTCTAAAGTTAAATCAAAGGTGGTTTGTCT AGCAGAGAGCCAGAATCTTCTAATAGTGGGCAGAGCCCAGAGACAAGGGGAAGAAAGATGACCTTCTCCCCAGTCCTTCCCAGCACCATT TTTGTTTCACACCAGGCTTGTGGCATTTTGGTGCTCACAGGGGTTTTGCCTTCTGACCTCTCCTTGGAGTAGGCCATTCTCATGCAGGGC TCACCCTGAGGCAGGAGGACCAAGGGCTCCCTGCGTCCACGGACCACGTATGCCTTGGTGGTCACTCCCATCGGGGCTATCAGTTCTGCA CTGTGCCCTGGTGCGGATTTTAATGCATATTTTTATATATAAATGTTCCCAAAGGCCAAATTTGTTGCCAGGTTTTATACGCAGGTCACC >In-frame_PTPRU_ENST00000460170_chr1_29563229_+_UBIAD1_ENST00000376810_chr1_11345701_+_2870nt CCAACCATGGCCCGTGCCCAGGCGCTCGTGCTGGCACTCACCTTCCAGCTCTGCGCGCCGGAGACCGAGACTCCGGCAGGAATTGGATTC AAGTACGTGGCTCTGGGAGACCTCATCATCCTCATCACTTTTGGCCCGCTGGCTGTGATGTTCGCCTACGCCATCCAGGTGGGGTCCCTG GCCATCTTCCCACTGGTCTATGCCATCCCCCTCGCCCTCAGCACCGAGGCCATTCTCCATTCCAACAACACCAGGGACATGGAGTCCGAC CGGGAGGCTGGTATCGTCACGCTGGCCATCCTCATCGGCCCCACGTTCTCCTACATTCTCTACAACACACTGCTCTTCCTGCCCTACCTG GTCTTCAGCATCCTGGCCACACACTGCACCATCAGCCTGGCACTCCCCCTGCTTACCATTCCCATGGCCTTCTCCCTTGAGAGACAGTTT CGAAGCCAGGCCTTCAACAAACTGCCCCAGAGGACTGCCAAGCTCAACCTCCTGCTGGGACTTTTCTATGTCTTTGGCATCATTCTGGCA CCAGCAGGCAGTCTGCCCAAAATTTAAGGGGACAAGTAGCTCCCCCCACGACATGTCTCCCTTTCTTAGAATATATTAAAGTCAGAGTCT CTGAGGAAGGAATGTGATTTGGCAGTCAGGGTACTAAGCATGGGTGGGAACTCCTGCCTTATAAAAATTGTTTTTGTGTTCTTAAAGATA ATATGTTGTTTTTCTGTTTTTTGTTTTTTCCATTTTATGGGGAATTTAAAAACCATTCTTGTATCAGAAGGTGAATTAGGCGCATGGTCT TTGTTTTATTAATAATTTCCACTAGAGGGTGTTCTCAGGTCACTTTGCAGTGAAGTGGACTTAGTTCCTCCTTGTTCTGTACAAAATGTC TCCAGACTTTGTAAAGGAGCTGCCCAGTTTGGCCTCCTGTCCCGAAAAGACCCTAATAACTAGGCAGAGTGTTGTCCTGCTTTCTTCGTC TCGTAGGATGTGCTATGATTGGTGCCAGGCCTCACTAACACAGGGGCTACCTGTCTCTTATTCTCAGCACCTGTGTCCTGAGATACGCTG CCTGAGACAGAGAGAGTCCCTCATTAACAGCCTGTGTGGCTGTCAGCTTTTTGCCTAAATTGTGATTCAGATGCTTTTGTTCTCTCTCCT TTCACTTATTGCCACAGTTGAGGAAAAGTGTCAGATTACCCTGCAGCAAGACAAGCCAAGGACTGGGAGGGAAAAAAAAACCACTCTGGA GGCAACTGAGAAAATCACTGCTTTTGGATAGGAATCAGTAGGGTGGCTGTTTTCCCTTTGTTGAATCTACTAGAGTGACAGGAAGGACTC CCAGCCCTTTCAGTAACTATCAGGAGCCCTGAAACGGTAGAGGCACTGCCATCCTTGTGGGATACTCAAAGCCCACAGGGCTTTTCCCTC CCTATTGCATCTTCTGATGCTCCCCACACCTACCCTCCACCTCTCCACCTCTGTGGTGTTCCCATTTGTGTGTTTCCCATCTGTGGAGCC AGACTGAGCAATAGCTTAGCAGCGAGTCAGGGACAGCTGCCACTTTCCACAGAGCCACAGGATGGGCAGAGCAGGGACCCAGGGAATGAA TAGCCAGTGGACAAACAGTCTTGAGCTCTGTTCAGCCAGAGTGATGGGCCCTGCCAGTTAAGGGGCTGTGTCTTCATCCTTGAAGACAGA TGTGCAATATTGACCCTGCCTCTCCCCAGGGCTTTGTGGAAAGATAGTTGAGGGCTTTAGTGAGATCACACTCAGAGTGGGGCAATTCCA GCATTTATCCTGGCTGCGTTTCATTGCATTGTCTGTGAAGTATAATTTCTGGGCCAGAATTGCTCAGTTGCATTTGATCCAGGACTATAG ATTGGAAATGGGTCATCATTGTTTTCTGTTGTGATTATAGCCATTCTAGTAGGCGTTTAAGGTCATGGCCTGCAGAAAATGATGTAAGAA CTAGTTCTTAATCTTTCAGATCAAGCTAATGATGATATGGAACCTTGAGTTCGAATTGATTGGTTTACTTGGAAAAAAACATGTTTGAAA ATTGCAAAAGTTCCGCCGGGCGCGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGACGGGCGGATCACGAGGTCAGGAGAT CGAGACCATCTTGGCTAACACGGTGAAACCCCGTTTCTACTAAAAATACAAAAAATTAGCCAGGCGTGTTGGCGGGCGCCTGTAGTCCCA GCTACCTGGGCGGCTGAGGCAGGAGCATGGCGTGAACCCAGGAGGCGGAGCTTGCAGTGAGCTGAGATCATGCCACTGCACTCCAACCTG GGGGACACAGCAAGACTCCGTCTCAAAAAAAAAAAAAGAAAAAGAAAATTGCAAAAGTTCCTCTAAAGTTAAATCAAAGGTGGTTTGTCT AGCAGAGAGCCAGAATCTTCTAATAGTGGGCAGAGCCCAGAGACAAGGGGAAGAAAGATGACCTTCTCCCCAGTCCTTCCCAGCACCATT TTTGTTTCACACCAGGCTTGTGGCATTTTGGTGCTCACAGGGGTTTTGCCTTCTGACCTCTCCTTGGAGTAGGCCATTCTCATGCAGGGC TCACCCTGAGGCAGGAGGACCAAGGGCTCCCTGCGTCCACGGACCACGTATGCCTTGGTGGTCACTCCCATCGGGGCTATCAGTTCTGCA CTGTGCCCTGGTGCGGATTTTAATGCATATTTTTATATATAAATGTTCCCAAAGGCCAAATTTGTTGCCAGGTTTTATACGCAGGTCACC |
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FusionGenePPI for PTPRU_UBIAD1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| PTPRU | CTNNB1, IRS1, SGCA, AAMP, EGFR, ERBB2, ARL2, ARHGAP5, NHS, NHSL1, ST7, TMEM57, ABI2, PTPRK, GOLIM4, PCDHGB1, FAM19A4, CLEC2D, ZNRF4, CDH5, SCGB1D1, PCDHGB4 | UBIAD1 | TMEM17, TMEM216, ADD1, HMGCR, SOAT1, VEGFA |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for PTPRU_UBIAD1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for PTPRU_UBIAD1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | UBIAD1 | C0271287 | Schnyder crystalline corneal dystrophy | 7 | CTD_human;HPO;ORPHANET;UNIPROT |
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