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Fusion gene ID: 29522 |
FusionGeneSummary for PTPRG_ZNF236 |
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Fusion gene information | Fusion gene name: PTPRG_ZNF236 | Fusion gene ID: 29522 | Hgene | Tgene | Gene symbol | PTPRG | ZNF236 | Gene ID | 5793 | 7776 |
Gene name | protein tyrosine phosphatase, receptor type G | zinc finger protein 236 | |
Synonyms | HPTPG|PTPG|R-PTP-GAMMA|RPTPG | ZNF236A|ZNF236B | |
Cytomap | 3p14.2 | 18q23 | |
Type of gene | protein-coding | protein-coding | |
Description | receptor-type tyrosine-protein phosphatase gammaH_RG317H01.1protein tyrosine phosphatase gammaprotein tyrosine phosphatase, receptor type, gamma polypeptidereceptor type protein tyrosine phosphatase gammareceptor tyrosine phosphatase gammareceptor-t | zinc finger protein 236regulated by glucose | |
Modification date | 20180527 | 20180519 | |
UniProtAcc | P23470 | Q9UL36 | |
Ensembl transtripts involved in fusion gene | ENST00000295874, ENST00000474889, ENST00000495879, | ENST00000320610, ENST00000253159, ENST00000583095, | |
Fusion gene scores | * DoF score | 11 X 6 X 7=462 | 3 X 3 X 1=9 |
# samples | 13 | 3 | |
** MAII score | log2(13/462*10)=-1.8293812283876 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/9*10)=1.73696559416621 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
Context | PubMed: PTPRG [Title/Abstract] AND ZNF236 [Title/Abstract] AND fusion [Title/Abstract] | ||
Functional or gene categories assigned by FusionGDB annotation |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
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Partner | Gene | GO ID | GO term | PubMed ID |
![]() (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChiTaRS3.1 | BI052221 | PTPRG | chr3 | 61756318 | - | ZNF236 | chr18 | 74681364 | + |
* LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
intron-3UTR | ENST00000295874 | ENST00000320610 | PTPRG | chr3 | 61756318 | - | ZNF236 | chr18 | 74681364 | + |
intron-3UTR | ENST00000295874 | ENST00000253159 | PTPRG | chr3 | 61756318 | - | ZNF236 | chr18 | 74681364 | + |
intron-intron | ENST00000295874 | ENST00000583095 | PTPRG | chr3 | 61756318 | - | ZNF236 | chr18 | 74681364 | + |
intron-3UTR | ENST00000474889 | ENST00000320610 | PTPRG | chr3 | 61756318 | - | ZNF236 | chr18 | 74681364 | + |
intron-3UTR | ENST00000474889 | ENST00000253159 | PTPRG | chr3 | 61756318 | - | ZNF236 | chr18 | 74681364 | + |
intron-intron | ENST00000474889 | ENST00000583095 | PTPRG | chr3 | 61756318 | - | ZNF236 | chr18 | 74681364 | + |
3UTR-3UTR | ENST00000495879 | ENST00000320610 | PTPRG | chr3 | 61756318 | - | ZNF236 | chr18 | 74681364 | + |
3UTR-3UTR | ENST00000495879 | ENST00000253159 | PTPRG | chr3 | 61756318 | - | ZNF236 | chr18 | 74681364 | + |
3UTR-intron | ENST00000495879 | ENST00000583095 | PTPRG | chr3 | 61756318 | - | ZNF236 | chr18 | 74681364 | + |
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FusionProtFeatures for PTPRG_ZNF236 |
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Hgene | Tgene |
PTPRG | ZNF236 |
Possesses tyrosine phosphatase activity.{ECO:0000269|PubMed:19167335}. | May be involved in transcriptional regulation. |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for PTPRG_ZNF236 |
![]() (nt: nucleotides, aa: amino acids) |
* Fusion amino acid sequences. |
* Fusion transcript sequences (only coding sequence (CDS) region). |
* Fusion transcript sequences (Full-length transcript). |
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FusionGenePPI for PTPRG_ZNF236 |
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Hgene | Hgene's interactors | Tgene | Tgene's interactors |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for PTPRG_ZNF236 |
![]() (DrugBank Version 5.1.0 2018-04-02) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for PTPRG_ZNF236 |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Hgene | PTPRG | C0038356 | Stomach Neoplasms | 1 | CTD_human |