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Fusion gene ID: 29054 |
FusionGeneSummary for PSAP_PCID2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PSAP_PCID2 | Fusion gene ID: 29054 | Hgene | Tgene | Gene symbol | PSAP | PCID2 | Gene ID | 729238 | 55795 |
| Gene name | surfactant protein A2 | PCI domain containing 2 | |
| Synonyms | COLEC5|PSAP|PSP-A|PSPA|SFTP1|SFTPA2B|SP-2A|SP-A|SPA2|SPAII | F10 | |
| Cytomap | 10q22.3 | 13q34 | |
| Type of gene | protein-coding | protein-coding | |
| Description | pulmonary surfactant-associated protein A235 kDa pulmonary surfactant-associated proteinalveolar proteinosis proteincollectin 5surfactant, pulmonary-associated protein A2A | PCI domain-containing protein 2CSN12-like protein | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | P07602 | Q5JVF3 | |
| Ensembl transtripts involved in fusion gene | ENST00000394936, ENST00000394934, | ENST00000337344, ENST00000375477, ENST00000375479, ENST00000493650, ENST00000375459, ENST00000246505, ENST00000375457, | |
| Fusion gene scores | * DoF score | 32 X 20 X 10=6400 | 2 X 1 X 2=4 |
| # samples | 37 | 2 | |
| ** MAII score | log2(37/6400*10)=-4.11247472925841 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/4*10)=2.32192809488736 | |
| Context | PubMed: PSAP [Title/Abstract] AND PCID2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | UCEC | TCGA-AJ-A3TW-01A | PSAP | chr10 | 73610939 | - | PCID2 | chr13 | 113854830 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000394936 | ENST00000337344 | PSAP | chr10 | 73610939 | - | PCID2 | chr13 | 113854830 | - |
| In-frame | ENST00000394936 | ENST00000375477 | PSAP | chr10 | 73610939 | - | PCID2 | chr13 | 113854830 | - |
| In-frame | ENST00000394936 | ENST00000375479 | PSAP | chr10 | 73610939 | - | PCID2 | chr13 | 113854830 | - |
| 5CDS-intron | ENST00000394936 | ENST00000493650 | PSAP | chr10 | 73610939 | - | PCID2 | chr13 | 113854830 | - |
| 5CDS-intron | ENST00000394936 | ENST00000375459 | PSAP | chr10 | 73610939 | - | PCID2 | chr13 | 113854830 | - |
| 5CDS-intron | ENST00000394936 | ENST00000246505 | PSAP | chr10 | 73610939 | - | PCID2 | chr13 | 113854830 | - |
| 5CDS-intron | ENST00000394936 | ENST00000375457 | PSAP | chr10 | 73610939 | - | PCID2 | chr13 | 113854830 | - |
| In-frame | ENST00000394934 | ENST00000337344 | PSAP | chr10 | 73610939 | - | PCID2 | chr13 | 113854830 | - |
| In-frame | ENST00000394934 | ENST00000375477 | PSAP | chr10 | 73610939 | - | PCID2 | chr13 | 113854830 | - |
| In-frame | ENST00000394934 | ENST00000375479 | PSAP | chr10 | 73610939 | - | PCID2 | chr13 | 113854830 | - |
| 5CDS-intron | ENST00000394934 | ENST00000493650 | PSAP | chr10 | 73610939 | - | PCID2 | chr13 | 113854830 | - |
| 5CDS-intron | ENST00000394934 | ENST00000375459 | PSAP | chr10 | 73610939 | - | PCID2 | chr13 | 113854830 | - |
| 5CDS-intron | ENST00000394934 | ENST00000246505 | PSAP | chr10 | 73610939 | - | PCID2 | chr13 | 113854830 | - |
| 5CDS-intron | ENST00000394934 | ENST00000375457 | PSAP | chr10 | 73610939 | - | PCID2 | chr13 | 113854830 | - |
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FusionProtFeatures for PSAP_PCID2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| PSAP | PCID2 |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >PCID2 | chr10:73610939 | chr13:113854830 | ENST00000246505 | - | 0 | 15 | 210_391 | 12 | 560 | Domain | PCI |
| Tgene | >PCID2 | chr10:73610939 | chr13:113854830 | ENST00000337344 | - | 0 | 14 | 210_391 | 12 | 400 | Domain | PCI |
| Tgene | >PCID2 | chr10:73610939 | chr13:113854830 | ENST00000375457 | - | 0 | 14 | 210_391 | 10 | 398 | Domain | PCI |
| Tgene | >PCID2 | chr10:73610939 | chr13:113854830 | ENST00000375459 | - | 0 | 15 | 210_391 | 10 | 510 | Domain | PCI |
| Tgene | >PCID2 | chr10:73610939 | chr13:113854830 | ENST00000375477 | - | 0 | 15 | 210_391 | 12 | 518 | Domain | PCI |
| Tgene | >PCID2 | chr10:73610939 | chr13:113854830 | ENST00000375479 | - | 0 | 15 | 210_391 | 12 | 491 | Domain | PCI |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >PSAP | chr10:73610939 | chr13:113854830 | ENST00000394936 | - | 1 | 14 | 18_58 | 13 | 525 | Domain | Saposin A-type 1 |
| Hgene | >PSAP | chr10:73610939 | chr13:113854830 | ENST00000394936 | - | 1 | 14 | 194_275 | 13 | 525 | Domain | Saposin B-type 2 |
| Hgene | >PSAP | chr10:73610939 | chr13:113854830 | ENST00000394936 | - | 1 | 14 | 311_392 | 13 | 525 | Domain | Saposin B-type 3 |
| Hgene | >PSAP | chr10:73610939 | chr13:113854830 | ENST00000394936 | - | 1 | 14 | 405_486 | 13 | 525 | Domain | Saposin B-type 4 |
| Hgene | >PSAP | chr10:73610939 | chr13:113854830 | ENST00000394936 | - | 1 | 14 | 488_524 | 13 | 525 | Domain | Saposin A-type 2 |
| Hgene | >PSAP | chr10:73610939 | chr13:113854830 | ENST00000394936 | - | 1 | 14 | 59_142 | 13 | 525 | Domain | Saposin B-type 1 |
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FusionGeneSequence for PSAP_PCID2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_PSAP_ENST00000394936_chr10_73610939_-_PCID2_ENST00000337344_chr13_113854830_-_401aa MYALFLLASLLGAGVRSHRQQRWSILCRVGVFXTSSCCKPTTSNGLSRGEVSTSLGTPLXXNVCSSFKVHLCSGESXLHRGIQVPDRDSP IILASIPGPQRRKLGSACHVCSSAXPSSVCQXCRSTVGKERKKQSWGHVGKSSRVTDELFPGLCQRHPCWYRGLXEVGHAVSGEPAVXNL LQDQQTPFMXTPNXSNXQLKPERRLQHCTESNIQILRWTQGYVXQRFXASXGVPVICLXALSPFXSEEQKDDSDLFASSKNAIGSHAHCG APEKVSPDAVCGSNQSCERGQPAAAARGAGEARGLLHSLRNLPHPGEAEDHHLQEPLXESVFVTENTPAVSGCFSGCLEVHAGGGRGHXR >In-frame_PSAP_ENST00000394936_chr10_73610939_-_PCID2_ENST00000375477_chr13_113854830_-_13aa >In-frame_PSAP_ENST00000394936_chr10_73610939_-_PCID2_ENST00000375479_chr13_113854830_-_13aa >In-frame_PSAP_ENST00000394934_chr10_73610939_-_PCID2_ENST00000337344_chr13_113854830_-_401aa MYALFLLASLLGAGVRSHRQQRWSILCRVGVFXTSSCCKPTTSNGLSRGEVSTSLGTPLXXNVCSSFKVHLCSGESXLHRGIQVPDRDSP IILASIPGPQRRKLGSACHVCSSAXPSSVCQXCRSTVGKERKKQSWGHVGKSSRVTDELFPGLCQRHPCWYRGLXEVGHAVSGEPAVXNL LQDQQTPFMXTPNXSNXQLKPERRLQHCTESNIQILRWTQGYVXQRFXASXGVPVICLXALSPFXSEEQKDDSDLFASSKNAIGSHAHCG APEKVSPDAVCGSNQSCERGQPAAAARGAGEARGLLHSLRNLPHPGEAEDHHLQEPLXESVFVTENTPAVSGCFSGCLEVHAGGGRGHXR >In-frame_PSAP_ENST00000394934_chr10_73610939_-_PCID2_ENST00000375477_chr13_113854830_-_13aa >In-frame_PSAP_ENST00000394934_chr10_73610939_-_PCID2_ENST00000375479_chr13_113854830_-_13aa |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_PSAP_ENST00000394936_chr10_73610939_-_PCID2_ENST00000337344_chr13_113854830_-_1204nt ATGTACGCCCTCTTCCTCCTGGCCAGCCTCCTGGGCGCGGGTGTACGAAGCCATCGACAGCAGAGATGGAGCATCTTGTGCAGAGTTGGT GTCTTTTAAACATCCTCATGTTGCAAACCCACGACTTCAAATGGCCTCTCCAGAGGAGAAGTGTCAACAAGTCTTGGAACCCCCTTATGA TGAAATGTTTGCAGCTCATTTAAGGTGCACTTATGCAGTGGGGAATCATGACTTCATAGAGGCATACAAGTGCCAGACCGTGATAGTCCA ATCATTCTTGCGAGCATTCCAGGCCCACAAAGAAGAAAACTGGGCTCTGCCTGTCATGTATGCAGTAGCGCTTGACCTTCGAGTGTTTGC CAATAATGCAGATCAACAGTTGGTAAAGAAAGGAAAAAGCAAAGTTGGGGACATGTTGGAAAAAGCAGCAGAGTTACTGATGAGCTGTTT CCGGGTCTGTGCCAGCGACACCCGTGCTGGTATAGAGGACTCTAAGAAGTGGGGCATGCTGTTTCTGGTGAACCAGCTGTTTAAAATCTA CTTCAAGATCAACAAACTCCATTTATGTAAACCCCTAATTAGAGCAATTGACAGCTCAAACCTGAAAGACGATTACAGCACTGCACAGAG AGTAACATACAAATACTACGTTGGACGCAAGGCTATGTTTGACAGCGATTTTAAGCAAGCTGAGGAGTACCTGTCATTTGCCTTTGAGCA TTGTCACCGTTCTAGTCAGAAGAACAAAAGGATGATTCTGATCTATTTGCTTCCAGTAAAAATGCTATTGGGTCACATGCCCACTGTGGA GCTCCTGAAAAAGTATCACCTGATGCAGTTTGCGGAAGTAACCAGAGCTGTGAGCGAGGGCAACCTGCTGCTGCTGCACGAGGCGCTGGC GAAGCACGAGGCCTTCTTCATTCGCTGCGGAATCTTCCTCATCCTGGAGAAGCTGAAGATCATCACCTACAGGAACCTCTTTAAGAAAGT GTATTTGTTACTGAAAACACACCAGCTGTCTCTGGATGCTTTTCTGGTTGCCTTGAAGTTCATGCAGGTGGAGGACGTGGACATTGACGA AGTTCAGTGTATTCTGGCTAACTTGATATACATGGGACACGTCAAAGGCTACATATCGCATCAGCATCAGAAGCTGGTGGTCAGCAAGCA >In-frame_PSAP_ENST00000394936_chr10_73610939_-_PCID2_ENST00000375477_chr13_113854830_-_40nt >In-frame_PSAP_ENST00000394936_chr10_73610939_-_PCID2_ENST00000375479_chr13_113854830_-_40nt >In-frame_PSAP_ENST00000394934_chr10_73610939_-_PCID2_ENST00000337344_chr13_113854830_-_1204nt ATGTACGCCCTCTTCCTCCTGGCCAGCCTCCTGGGCGCGGGTGTACGAAGCCATCGACAGCAGAGATGGAGCATCTTGTGCAGAGTTGGT GTCTTTTAAACATCCTCATGTTGCAAACCCACGACTTCAAATGGCCTCTCCAGAGGAGAAGTGTCAACAAGTCTTGGAACCCCCTTATGA TGAAATGTTTGCAGCTCATTTAAGGTGCACTTATGCAGTGGGGAATCATGACTTCATAGAGGCATACAAGTGCCAGACCGTGATAGTCCA ATCATTCTTGCGAGCATTCCAGGCCCACAAAGAAGAAAACTGGGCTCTGCCTGTCATGTATGCAGTAGCGCTTGACCTTCGAGTGTTTGC CAATAATGCAGATCAACAGTTGGTAAAGAAAGGAAAAAGCAAAGTTGGGGACATGTTGGAAAAAGCAGCAGAGTTACTGATGAGCTGTTT CCGGGTCTGTGCCAGCGACACCCGTGCTGGTATAGAGGACTCTAAGAAGTGGGGCATGCTGTTTCTGGTGAACCAGCTGTTTAAAATCTA CTTCAAGATCAACAAACTCCATTTATGTAAACCCCTAATTAGAGCAATTGACAGCTCAAACCTGAAAGACGATTACAGCACTGCACAGAG AGTAACATACAAATACTACGTTGGACGCAAGGCTATGTTTGACAGCGATTTTAAGCAAGCTGAGGAGTACCTGTCATTTGCCTTTGAGCA TTGTCACCGTTCTAGTCAGAAGAACAAAAGGATGATTCTGATCTATTTGCTTCCAGTAAAAATGCTATTGGGTCACATGCCCACTGTGGA GCTCCTGAAAAAGTATCACCTGATGCAGTTTGCGGAAGTAACCAGAGCTGTGAGCGAGGGCAACCTGCTGCTGCTGCACGAGGCGCTGGC GAAGCACGAGGCCTTCTTCATTCGCTGCGGAATCTTCCTCATCCTGGAGAAGCTGAAGATCATCACCTACAGGAACCTCTTTAAGAAAGT GTATTTGTTACTGAAAACACACCAGCTGTCTCTGGATGCTTTTCTGGTTGCCTTGAAGTTCATGCAGGTGGAGGACGTGGACATTGACGA AGTTCAGTGTATTCTGGCTAACTTGATATACATGGGACACGTCAAAGGCTACATATCGCATCAGCATCAGAAGCTGGTGGTCAGCAAGCA >In-frame_PSAP_ENST00000394934_chr10_73610939_-_PCID2_ENST00000375477_chr13_113854830_-_40nt >In-frame_PSAP_ENST00000394934_chr10_73610939_-_PCID2_ENST00000375479_chr13_113854830_-_40nt |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_PSAP_ENST00000394936_chr10_73610939_-_PCID2_ENST00000337344_chr13_113854830_-_1973nt GCTGAGTCAGGGCGCTGTTGAGCTCGGGCAGGCCCGGATGGGGCGGGGTTAGCGCCTGCGCTCTGGACGGCTTTGGGGCAGGGCAGATTT ATATCTGCGGGGGATCAGCTGACGCTCCGCATTGCAGACTGCGGAGTCAGACGGCGCTATGTACGCCCTCTTCCTCCTGGCCAGCCTCCT GGGCGCGGGTGTACGAAGCCATCGACAGCAGAGATGGAGCATCTTGTGCAGAGTTGGTGTCTTTTAAACATCCTCATGTTGCAAACCCAC GACTTCAAATGGCCTCTCCAGAGGAGAAGTGTCAACAAGTCTTGGAACCCCCTTATGATGAAATGTTTGCAGCTCATTTAAGGTGCACTT ATGCAGTGGGGAATCATGACTTCATAGAGGCATACAAGTGCCAGACCGTGATAGTCCAATCATTCTTGCGAGCATTCCAGGCCCACAAAG AAGAAAACTGGGCTCTGCCTGTCATGTATGCAGTAGCGCTTGACCTTCGAGTGTTTGCCAATAATGCAGATCAACAGTTGGTAAAGAAAG GAAAAAGCAAAGTTGGGGACATGTTGGAAAAAGCAGCAGAGTTACTGATGAGCTGTTTCCGGGTCTGTGCCAGCGACACCCGTGCTGGTA TAGAGGACTCTAAGAAGTGGGGCATGCTGTTTCTGGTGAACCAGCTGTTTAAAATCTACTTCAAGATCAACAAACTCCATTTATGTAAAC CCCTAATTAGAGCAATTGACAGCTCAAACCTGAAAGACGATTACAGCACTGCACAGAGAGTAACATACAAATACTACGTTGGACGCAAGG CTATGTTTGACAGCGATTTTAAGCAAGCTGAGGAGTACCTGTCATTTGCCTTTGAGCATTGTCACCGTTCTAGTCAGAAGAACAAAAGGA TGATTCTGATCTATTTGCTTCCAGTAAAAATGCTATTGGGTCACATGCCCACTGTGGAGCTCCTGAAAAAGTATCACCTGATGCAGTTTG CGGAAGTAACCAGAGCTGTGAGCGAGGGCAACCTGCTGCTGCTGCACGAGGCGCTGGCGAAGCACGAGGCCTTCTTCATTCGCTGCGGAA TCTTCCTCATCCTGGAGAAGCTGAAGATCATCACCTACAGGAACCTCTTTAAGAAAGTGTATTTGTTACTGAAAACACACCAGCTGTCTC TGGATGCTTTTCTGGTTGCCTTGAAGTTCATGCAGGTGGAGGACGTGGACATTGACGAAGTTCAGTGTATTCTGGCTAACTTGATATACA TGGGACACGTCAAAGGCTACATATCGCATCAGCATCAGAAGCTGGTGGTCAGCAAGCAGAACCCATTTCCTCCCCTGTCCACGGTGTGTT GAAAGTACACGGAGCCCCGAGGACGGGTGAGCAGTTGTTTCTTTCCACTTTGGTTGTGCTGATGAGACCGGTCCGGTACTGCAACAAGGC TCCCTGAAGCCGGAACTCTTGGAGGCGCTTTTCCCAGGGATGCTGAGGCTGAGATTTTCAGCACACCCGAGTTAATCTCCTTCATTTGTA ACTAATTTCAGCCTGATGAAAACCTGGAATTCCTTTTTCACAGACTCGGCTGGTTCTGGAGTCTTTGTGAGACTTCTTTGAAGGAGGCTT TGCGTGAAGGCTGCTCGGCTCACTTTTCCTAAGTGTGGTTCCTGAAGGCTGTCTTTGTAACTTTTTGTAGTTCTTTGTGTAAAAAGCGTA TTCTGAATTTATACACATGGCATGTTCTTCATTATATCTTCCAGGATACATCTATTTTTATATATTAAATTTGAATGTGTTATCAAAATG CTTGGTTAACTTAAGGCACCTTTTTAAAAGCAGAATTTAATTTGATTTAAATTTTCCAGATTTTATAGCTTGCCTGTATGGATGCTCCTC >In-frame_PSAP_ENST00000394936_chr10_73610939_-_PCID2_ENST00000375477_chr13_113854830_-_1774nt GCTGAGTCAGGGCGCTGTTGAGCTCGGGCAGGCCCGGATGGGGCGGGGTTAGCGCCTGCGCTCTGGACGGCTTTGGGGCAGGGCAGATTT ATATCTGCGGGGGATCAGCTGACGCTCCGCATTGCAGACTGCGGAGTCAGACGGCGCTATGTACGCCCTCTTCCTCCTGGCCAGCCTCCT GGGCGCGGGTGTACGAAGCCATCGACAGCAGAGATGGAGCATCTTGTGCAGAGTTGGTGTCTTTTAAACATCCTCATGTTGCAAACCCAC GACTTCAAATGGCCTCTCCAGAGGAGAAGTGTCAACAAGTCTTGGAACCCCCTTATGATGAAATGTTTGCAGCTCATTTAAGGTGCACTT ATGCAGTGGGGAATCATGACTTCATAGAGGCATACAAGTGCCAGACCGTGATAGTCCAATCATTCTTGCGAGCATTCCAGGCCCACAAAG AAGAAAACTGGGCTCTGCCTGTCATGTATGCAGTAGCGCTTGACCTTCGAGTGTTTGCCAATAATGCAGATCAACAGTTGGTAAAGAAAG GAAAAAGCAAAGTTGGGGACATGTTGGAAAAAGCAGCAGAGTTACTGATGAGCTGTTTCCGGGTCTGTGCCAGCGACACCCGTGCTGGTA TAGAGGACTCTAAGAAGTGGGGCATGCTGTTTCTGGTGAACCAGCTGTTTAAAATCTACTTCAAGATCAACAAACTCCATTTATGTAAAC CCCTAATTAGAGCAATTGACAGCTCAAACCTGAAAGACGATTACAGCACTGCACAGAGAGTAACATACAAATACTACGTTGGACGCAAGG CTATGTTTGACAGCGATTTTAAGCAAGCTGAGGAGTACCTGTCATTTGCCTTTGAGCATTGTCACCGTTCTAGTCAGAAGAACAAAAGGA TGATTCTGATCTATTTGCTTCCAGTAAAAATGCTATTGGGTCACATGCCCACTGTGGAGCTCCTGAAAAAGTATCACCTGATGCAGTTTG CGGAAGTAACCAGAGCTGTGAGCGAGGGCAACCTGCTGCTGCTGCACGAGGCGCTGGCGAAGCACGAGGCCTTCTTCATTCGCTGCGGAA TCTTCCTCATCCTGGAGAAGCTGAAGATCATCACCTACAGGAACCTCTTTAAGAAAGTGTATTTGTTACTGAAAACACACCAGCTGTCTC TGGATGCTTTTCTGGTTGCCTTGAAGTTCATGCAGGTGGAGGACGTGGACATTGACGAAGTTCAGTGTATTCTGGCTAACTTGATATACA TGGGACACGTCAAAGGCTACATATCGCATCAGCATCAGAAGCTGGTGGTCAGCAAGCAGAACCCATTTCCTCCCCTGTCCACGGTGTGTT GAAAGTACACGGAGCCCCGAGGACGGCCTGATGAAAACCTGGAATTCCTTTTTCACAGACTCGGCTGGTTCTGGAGTCTTTGTGAGACTT CTTTGAAGGAGGCTTTGCGTGAAGGCTGCTCGGCTCACTTTTCCTAAGTGTGGTTCCTGAAGGCTGTCTTTGTAACTTTTTGTAGTTCTT TGTGTAAAAAGCGTATTCTGAATTTATACACATGGCATGTTCTTCATTATATCTTCCAGGATACATCTATTTTTATATATTAAATTTGAA TGTGTTATCAAAATGCTTGGTTAACTTAAGGCACCTTTTTAAAAGCAGAATTTAATTTGATTTAAATTTTCCAGATTTTATAGCTTGCCT >In-frame_PSAP_ENST00000394936_chr10_73610939_-_PCID2_ENST00000375479_chr13_113854830_-_1742nt GCTGAGTCAGGGCGCTGTTGAGCTCGGGCAGGCCCGGATGGGGCGGGGTTAGCGCCTGCGCTCTGGACGGCTTTGGGGCAGGGCAGATTT ATATCTGCGGGGGATCAGCTGACGCTCCGCATTGCAGACTGCGGAGTCAGACGGCGCTATGTACGCCCTCTTCCTCCTGGCCAGCCTCCT GGGCGCGGGTGTACGAAGCCATCGACAGCAGAGATGGAGCATCTTGTGCAGAGTTGGTGTCTTTTAAACATCCTCATGTTGCAAACCCAC GACTTCAAATGGCCTCTCCAGAGGAGAAGTGTCAACAAGTCTTGGAACCCCCTTATGATGAAATGTTTGCAGCTCATTTAAGGTGCACTT ATGCAGTGGGGAATCATGACTTCATAGAGGCATACAAGTGCCAGACCGTGATAGTCCAATCATTCTTGCGAGCATTCCAGGCCCACAAAG AAGAAAACTGGGCTCTGCCTGTCATGTATGCAGTAGCGCTTGACCTTCGAGTGTTTGCCAATAATGCAGATCAACAGTTGGTAAAGAAAG GAAAAAGCAAAGTTGGGGACATGTTGGAAAAAGCAGCAGAGTTACTGATGAGCTGTTTCCGGGTCTGTGCCAGCGACACCCGTGCTGGTA TAGAGGACTCTAAGAAGTGGGGCATGCTGTTTCTGGTGAACCAGCTGTTTAAAATCTACTTCAAGATCAACAAACTCCATTTATGTAAAC CCCTAATTAGAGCAATTGACAGCTCAAACCTGAAAGACGATTACAGCACTGCACAGAGAGTAACATACAAATACTACGTTGGACGCAAGG CTATGTTTGACAGCGATTTTAAGCAAGCTGAGGAGTACCTGTCATTTGCCTTTGAGCATTGTCACCGTTCTAGTCAGAAGAACAAAAGGA TGATTCTGATCTATTTGCTTCCAGTAAAAATGCTATTGGGTCACATGCCCACTGTGGAGCTCCTGAAAAAGTATCACCTGATGCAGTTTG CGGAAGTAACCAGAGCTGTGAGCGAGGGCAACCTGCTGCTGCTGCACGAGGCGCTGGCGAAGCACGAGGCCTTCTTCATTCGCTGCGGAA TCTTCCTCATCCTGGAGAAGCTGAAGATCATCACCTACAGGAACCTCTTTAAGAAAGTGTATTTGTTACTGAAAACACACCAGCTGTCTC TGGATGCTTTTCTGGTTGCCTTGAAGTTCATGCAGGTGGAGGACGTGGACATTGACGAAGTTCAGTGTATTCTGGCTAACTTGATATACA TGGGACACGTCAAAGGCTACATATCGCATCAGCATCAGAAGCTGGTGGTCAGCAAGCAGAACCCATTTCCTCCCCTGTCCACGGTGTGTT GAAAGTACACGGAGCCCCGAGGACGGACTCGGCTGGTTCTGGAGTCTTTGTGAGACTTCTTTGAAGGAGGCTTTGCGTGAAGGCTGCTCG GCTCACTTTTCCTAAGTGTGGTTCCTGAAGGCTGTCTTTGTAACTTTTTGTAGTTCTTTGTGTAAAAAGCGTATTCTGAATTTATACACA TGGCATGTTCTTCATTATATCTTCCAGGATACATCTATTTTTATATATTAAATTTGAATGTGTTATCAAAATGCTTGGTTAACTTAAGGC ACCTTTTTAAAAGCAGAATTTAATTTGATTTAAATTTTCCAGATTTTATAGCTTGCCTGTATGGATGCTCCTCAATTTATGATAGGGTTA >In-frame_PSAP_ENST00000394934_chr10_73610939_-_PCID2_ENST00000337344_chr13_113854830_-_1929nt GGGGTTAGCGCCTGCGCTCTGGACGGCTTTGGGGCAGGGCAGATTTATATCTGCGGGGGATCAGCTGACGCTCCGCATTGCAGACTGCGG AGTCAGACGGCGCTATGTACGCCCTCTTCCTCCTGGCCAGCCTCCTGGGCGCGGGTGTACGAAGCCATCGACAGCAGAGATGGAGCATCT TGTGCAGAGTTGGTGTCTTTTAAACATCCTCATGTTGCAAACCCACGACTTCAAATGGCCTCTCCAGAGGAGAAGTGTCAACAAGTCTTG GAACCCCCTTATGATGAAATGTTTGCAGCTCATTTAAGGTGCACTTATGCAGTGGGGAATCATGACTTCATAGAGGCATACAAGTGCCAG ACCGTGATAGTCCAATCATTCTTGCGAGCATTCCAGGCCCACAAAGAAGAAAACTGGGCTCTGCCTGTCATGTATGCAGTAGCGCTTGAC CTTCGAGTGTTTGCCAATAATGCAGATCAACAGTTGGTAAAGAAAGGAAAAAGCAAAGTTGGGGACATGTTGGAAAAAGCAGCAGAGTTA CTGATGAGCTGTTTCCGGGTCTGTGCCAGCGACACCCGTGCTGGTATAGAGGACTCTAAGAAGTGGGGCATGCTGTTTCTGGTGAACCAG CTGTTTAAAATCTACTTCAAGATCAACAAACTCCATTTATGTAAACCCCTAATTAGAGCAATTGACAGCTCAAACCTGAAAGACGATTAC AGCACTGCACAGAGAGTAACATACAAATACTACGTTGGACGCAAGGCTATGTTTGACAGCGATTTTAAGCAAGCTGAGGAGTACCTGTCA TTTGCCTTTGAGCATTGTCACCGTTCTAGTCAGAAGAACAAAAGGATGATTCTGATCTATTTGCTTCCAGTAAAAATGCTATTGGGTCAC ATGCCCACTGTGGAGCTCCTGAAAAAGTATCACCTGATGCAGTTTGCGGAAGTAACCAGAGCTGTGAGCGAGGGCAACCTGCTGCTGCTG CACGAGGCGCTGGCGAAGCACGAGGCCTTCTTCATTCGCTGCGGAATCTTCCTCATCCTGGAGAAGCTGAAGATCATCACCTACAGGAAC CTCTTTAAGAAAGTGTATTTGTTACTGAAAACACACCAGCTGTCTCTGGATGCTTTTCTGGTTGCCTTGAAGTTCATGCAGGTGGAGGAC GTGGACATTGACGAAGTTCAGTGTATTCTGGCTAACTTGATATACATGGGACACGTCAAAGGCTACATATCGCATCAGCATCAGAAGCTG GTGGTCAGCAAGCAGAACCCATTTCCTCCCCTGTCCACGGTGTGTTGAAAGTACACGGAGCCCCGAGGACGGGTGAGCAGTTGTTTCTTT CCACTTTGGTTGTGCTGATGAGACCGGTCCGGTACTGCAACAAGGCTCCCTGAAGCCGGAACTCTTGGAGGCGCTTTTCCCAGGGATGCT GAGGCTGAGATTTTCAGCACACCCGAGTTAATCTCCTTCATTTGTAACTAATTTCAGCCTGATGAAAACCTGGAATTCCTTTTTCACAGA CTCGGCTGGTTCTGGAGTCTTTGTGAGACTTCTTTGAAGGAGGCTTTGCGTGAAGGCTGCTCGGCTCACTTTTCCTAAGTGTGGTTCCTG AAGGCTGTCTTTGTAACTTTTTGTAGTTCTTTGTGTAAAAAGCGTATTCTGAATTTATACACATGGCATGTTCTTCATTATATCTTCCAG GATACATCTATTTTTATATATTAAATTTGAATGTGTTATCAAAATGCTTGGTTAACTTAAGGCACCTTTTTAAAAGCAGAATTTAATTTG ATTTAAATTTTCCAGATTTTATAGCTTGCCTGTATGGATGCTCCTCAATTTATGATAGGGTTACATCCCAATAAACTTATTTTATTTGCC >In-frame_PSAP_ENST00000394934_chr10_73610939_-_PCID2_ENST00000375477_chr13_113854830_-_1730nt GGGGTTAGCGCCTGCGCTCTGGACGGCTTTGGGGCAGGGCAGATTTATATCTGCGGGGGATCAGCTGACGCTCCGCATTGCAGACTGCGG AGTCAGACGGCGCTATGTACGCCCTCTTCCTCCTGGCCAGCCTCCTGGGCGCGGGTGTACGAAGCCATCGACAGCAGAGATGGAGCATCT TGTGCAGAGTTGGTGTCTTTTAAACATCCTCATGTTGCAAACCCACGACTTCAAATGGCCTCTCCAGAGGAGAAGTGTCAACAAGTCTTG GAACCCCCTTATGATGAAATGTTTGCAGCTCATTTAAGGTGCACTTATGCAGTGGGGAATCATGACTTCATAGAGGCATACAAGTGCCAG ACCGTGATAGTCCAATCATTCTTGCGAGCATTCCAGGCCCACAAAGAAGAAAACTGGGCTCTGCCTGTCATGTATGCAGTAGCGCTTGAC CTTCGAGTGTTTGCCAATAATGCAGATCAACAGTTGGTAAAGAAAGGAAAAAGCAAAGTTGGGGACATGTTGGAAAAAGCAGCAGAGTTA CTGATGAGCTGTTTCCGGGTCTGTGCCAGCGACACCCGTGCTGGTATAGAGGACTCTAAGAAGTGGGGCATGCTGTTTCTGGTGAACCAG CTGTTTAAAATCTACTTCAAGATCAACAAACTCCATTTATGTAAACCCCTAATTAGAGCAATTGACAGCTCAAACCTGAAAGACGATTAC AGCACTGCACAGAGAGTAACATACAAATACTACGTTGGACGCAAGGCTATGTTTGACAGCGATTTTAAGCAAGCTGAGGAGTACCTGTCA TTTGCCTTTGAGCATTGTCACCGTTCTAGTCAGAAGAACAAAAGGATGATTCTGATCTATTTGCTTCCAGTAAAAATGCTATTGGGTCAC ATGCCCACTGTGGAGCTCCTGAAAAAGTATCACCTGATGCAGTTTGCGGAAGTAACCAGAGCTGTGAGCGAGGGCAACCTGCTGCTGCTG CACGAGGCGCTGGCGAAGCACGAGGCCTTCTTCATTCGCTGCGGAATCTTCCTCATCCTGGAGAAGCTGAAGATCATCACCTACAGGAAC CTCTTTAAGAAAGTGTATTTGTTACTGAAAACACACCAGCTGTCTCTGGATGCTTTTCTGGTTGCCTTGAAGTTCATGCAGGTGGAGGAC GTGGACATTGACGAAGTTCAGTGTATTCTGGCTAACTTGATATACATGGGACACGTCAAAGGCTACATATCGCATCAGCATCAGAAGCTG GTGGTCAGCAAGCAGAACCCATTTCCTCCCCTGTCCACGGTGTGTTGAAAGTACACGGAGCCCCGAGGACGGCCTGATGAAAACCTGGAA TTCCTTTTTCACAGACTCGGCTGGTTCTGGAGTCTTTGTGAGACTTCTTTGAAGGAGGCTTTGCGTGAAGGCTGCTCGGCTCACTTTTCC TAAGTGTGGTTCCTGAAGGCTGTCTTTGTAACTTTTTGTAGTTCTTTGTGTAAAAAGCGTATTCTGAATTTATACACATGGCATGTTCTT CATTATATCTTCCAGGATACATCTATTTTTATATATTAAATTTGAATGTGTTATCAAAATGCTTGGTTAACTTAAGGCACCTTTTTAAAA GCAGAATTTAATTTGATTTAAATTTTCCAGATTTTATAGCTTGCCTGTATGGATGCTCCTCAATTTATGATAGGGTTACATCCCAATAAA >In-frame_PSAP_ENST00000394934_chr10_73610939_-_PCID2_ENST00000375479_chr13_113854830_-_1698nt GGGGTTAGCGCCTGCGCTCTGGACGGCTTTGGGGCAGGGCAGATTTATATCTGCGGGGGATCAGCTGACGCTCCGCATTGCAGACTGCGG AGTCAGACGGCGCTATGTACGCCCTCTTCCTCCTGGCCAGCCTCCTGGGCGCGGGTGTACGAAGCCATCGACAGCAGAGATGGAGCATCT TGTGCAGAGTTGGTGTCTTTTAAACATCCTCATGTTGCAAACCCACGACTTCAAATGGCCTCTCCAGAGGAGAAGTGTCAACAAGTCTTG GAACCCCCTTATGATGAAATGTTTGCAGCTCATTTAAGGTGCACTTATGCAGTGGGGAATCATGACTTCATAGAGGCATACAAGTGCCAG ACCGTGATAGTCCAATCATTCTTGCGAGCATTCCAGGCCCACAAAGAAGAAAACTGGGCTCTGCCTGTCATGTATGCAGTAGCGCTTGAC CTTCGAGTGTTTGCCAATAATGCAGATCAACAGTTGGTAAAGAAAGGAAAAAGCAAAGTTGGGGACATGTTGGAAAAAGCAGCAGAGTTA CTGATGAGCTGTTTCCGGGTCTGTGCCAGCGACACCCGTGCTGGTATAGAGGACTCTAAGAAGTGGGGCATGCTGTTTCTGGTGAACCAG CTGTTTAAAATCTACTTCAAGATCAACAAACTCCATTTATGTAAACCCCTAATTAGAGCAATTGACAGCTCAAACCTGAAAGACGATTAC AGCACTGCACAGAGAGTAACATACAAATACTACGTTGGACGCAAGGCTATGTTTGACAGCGATTTTAAGCAAGCTGAGGAGTACCTGTCA TTTGCCTTTGAGCATTGTCACCGTTCTAGTCAGAAGAACAAAAGGATGATTCTGATCTATTTGCTTCCAGTAAAAATGCTATTGGGTCAC ATGCCCACTGTGGAGCTCCTGAAAAAGTATCACCTGATGCAGTTTGCGGAAGTAACCAGAGCTGTGAGCGAGGGCAACCTGCTGCTGCTG CACGAGGCGCTGGCGAAGCACGAGGCCTTCTTCATTCGCTGCGGAATCTTCCTCATCCTGGAGAAGCTGAAGATCATCACCTACAGGAAC CTCTTTAAGAAAGTGTATTTGTTACTGAAAACACACCAGCTGTCTCTGGATGCTTTTCTGGTTGCCTTGAAGTTCATGCAGGTGGAGGAC GTGGACATTGACGAAGTTCAGTGTATTCTGGCTAACTTGATATACATGGGACACGTCAAAGGCTACATATCGCATCAGCATCAGAAGCTG GTGGTCAGCAAGCAGAACCCATTTCCTCCCCTGTCCACGGTGTGTTGAAAGTACACGGAGCCCCGAGGACGGACTCGGCTGGTTCTGGAG TCTTTGTGAGACTTCTTTGAAGGAGGCTTTGCGTGAAGGCTGCTCGGCTCACTTTTCCTAAGTGTGGTTCCTGAAGGCTGTCTTTGTAAC TTTTTGTAGTTCTTTGTGTAAAAAGCGTATTCTGAATTTATACACATGGCATGTTCTTCATTATATCTTCCAGGATACATCTATTTTTAT ATATTAAATTTGAATGTGTTATCAAAATGCTTGGTTAACTTAAGGCACCTTTTTAAAAGCAGAATTTAATTTGATTTAAATTTTCCAGAT |
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FusionGenePPI for PSAP_PCID2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| PSAP | CELSR1, SGK223, MAFF, COPS6, CTSD, PSAP, UBE3A, ZBED1, USP4, TCERG1, SMARCC2, SAP18, PLAUR, SNAP23, NUP133, DNAJA1, SURF4, GDAP1, U2AF1, SNRPA1, SUMO2, SNCA, SRSF5, SSR1, THRAP3, BRCA1, SMAD9, SMAD2, CFTR, FBXO6, BAG3, BCAT1, C1QBP, GTF2F1, LAMB2, MVP, USP48, VPS29, VPS35, ERBB2, NLGN3, SOD1 | PCID2 | SHFM1, NEK6, UBC, CUL3, SMAD2, EID1, TUBGCP3, IKZF3, SHMT2, MOV10, NXF1, CAPZB, DDX3X, IMPDH2, LSM1, ADPRHL2, TTC4, PSMD6, SNX2, SNX6, UBE4B, VPS35, IFI16, KIF11, TMEM63B, ZFC3H1, CETN1, TRIM25 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for PSAP_PCID2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for PSAP_PCID2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | PSAP | C0268262 | Metachromatic Leukodystrophy due to Saposin B Deficiency | 5 | CTD_human;UNIPROT |
| Hgene | PSAP | C1864651 | GAUCHER DISEASE, ATYPICAL, DUE TO SAPOSIN C DEFICIENCY | 2 | CTD_human;ORPHANET;UNIPROT |
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