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Fusion gene ID: 28939 |
FusionGeneSummary for PRR16_SCAMP1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PRR16_SCAMP1 | Fusion gene ID: 28939 | Hgene | Tgene | Gene symbol | PRR16 | SCAMP1 | Gene ID | 51334 | 9522 |
| Gene name | proline rich 16 | secretory carrier membrane protein 1 | |
| Synonyms | DSC54|LARGEN | SCAMP|SCAMP37 | |
| Cytomap | 5q23.1 | 5q14.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | protein Largenmesenchymal stem cell protein DSC54proline-rich protein 16 | secretory carrier-associated membrane protein 1 | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | Q569H4 | ||
| Ensembl transtripts involved in fusion gene | ENST00000407149, ENST00000379551, ENST00000505123, ENST00000446965, | ENST00000538629, ENST00000339292, | |
| Fusion gene scores | * DoF score | 2 X 2 X 2=8 | 1 X 1 X 1=1 |
| # samples | 2 | 1 | |
| ** MAII score | log2(2/8*10)=1.32192809488736 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: PRR16 [Title/Abstract] AND SCAMP1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | PRR16 | GO:0045727 | positive regulation of translation | 24656129 |
| Hgene | PRR16 | GO:0045793 | positive regulation of cell size | 24656129 |
| Tgene | SCAMP1 | GO:0015031 | protein transport | 15840657 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | LGG | TCGA-HT-A614-01A | PRR16 | chr5 | 119800340 | + | SCAMP1 | chr5 | 77711344 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000407149 | ENST00000538629 | PRR16 | chr5 | 119800340 | + | SCAMP1 | chr5 | 77711344 | + |
| 5CDS-3UTR | ENST00000407149 | ENST00000339292 | PRR16 | chr5 | 119800340 | + | SCAMP1 | chr5 | 77711344 | + |
| 5UTR-3CDS | ENST00000379551 | ENST00000538629 | PRR16 | chr5 | 119800340 | + | SCAMP1 | chr5 | 77711344 | + |
| 5UTR-3UTR | ENST00000379551 | ENST00000339292 | PRR16 | chr5 | 119800340 | + | SCAMP1 | chr5 | 77711344 | + |
| intron-3CDS | ENST00000505123 | ENST00000538629 | PRR16 | chr5 | 119800340 | + | SCAMP1 | chr5 | 77711344 | + |
| intron-3UTR | ENST00000505123 | ENST00000339292 | PRR16 | chr5 | 119800340 | + | SCAMP1 | chr5 | 77711344 | + |
| intron-3CDS | ENST00000446965 | ENST00000538629 | PRR16 | chr5 | 119800340 | + | SCAMP1 | chr5 | 77711344 | + |
| intron-3UTR | ENST00000446965 | ENST00000339292 | PRR16 | chr5 | 119800340 | + | SCAMP1 | chr5 | 77711344 | + |
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FusionProtFeatures for PRR16_SCAMP1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| PRR16 | SCAMP1 |
| Regulator of cell size that promotes cell size increaseindependently of mTOR and Hippo signaling pathways. Acts bystimulating the translation of specific mRNAs, including thoseencoding proteins affecting mitochondrial functions. Increasesmitochondrial mass and respiration. {ECO:0000269|PubMed:24656129}. | Lectin that binds to various sugars: galactose > mannose= fucose > N-acetylglucosamine > N-acetylgalactosamine(PubMed:10224141). Acts as a chemoattractant, probably involved inthe regulation of cell migration (PubMed:28301481).{ECO:0000269|PubMed:10224141, ECO:0000269|PubMed:28301481}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >PRR16 | chr5:119800340 | chr5:77711344 | ENST00000379551 | + | 1 | 3 | 33_70 | -12 | 282 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >PRR16 | chr5:119800340 | chr5:77711344 | ENST00000407149 | + | 1 | 2 | 33_70 | 53 | 305 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >PRR16 | chr5:119800340 | chr5:77711344 | ENST00000446965 | + | 1 | 3 | 33_70 | -94 | 235 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >PRR16 | chr5:119800340 | chr5:77711344 | ENST00000505123 | + | 1 | 4 | 33_70 | -124 | 235 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >PRR16 | chr5:119800340 | chr5:77711344 | ENST00000379551 | + | 1 | 3 | 102_291 | -12 | 282 | Compositional bias | Note=Pro-rich |
| Hgene | >PRR16 | chr5:119800340 | chr5:77711344 | ENST00000407149 | + | 1 | 2 | 102_291 | 53 | 305 | Compositional bias | Note=Pro-rich |
| Hgene | >PRR16 | chr5:119800340 | chr5:77711344 | ENST00000446965 | + | 1 | 3 | 102_291 | -94 | 235 | Compositional bias | Note=Pro-rich |
| Hgene | >PRR16 | chr5:119800340 | chr5:77711344 | ENST00000505123 | + | 1 | 4 | 102_291 | -124 | 235 | Compositional bias | Note=Pro-rich |
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FusionGeneSequence for PRR16_SCAMP1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_PRR16_ENST00000407149_chr5_119800340_+_SCAMP1_ENST00000538629_chr5_77711344_+_347aa MSAKSKGNPSSSCPAEGPPAASKTKVKEQIKIIVEDLELVLGDLKDVAKELKEPPPGGVKMPNVPNTQPAIMKPTEEHPAYTQIAKEHAL AQAELLKRQEELERKAAELDRREREMQNLSQHGRKNNWPPLPSNFPVGPCFYQDFSVDIPVEFQKTVKLMYYLWMFHAVTLFLNIFGCLA WFCVDSARAVDFGLSILWFLLFTPCSFVCWYRPLYGAFRSDSSFRFFVFFFVYICQFAVHVLQAAGFHNWGIGGWISSLTGLNQNIPVGI |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_PRR16_ENST00000407149_chr5_119800340_+_SCAMP1_ENST00000538629_chr5_77711344_+_1041nt ATGTCAGCCAAGTCCAAGGGGAACCCCTCCTCGTCCTGTCCAGCCGAGGGACCGCCGGCAGCCTCCAAAACCAAGGTGAAGGAACAGATC AAGATCATCGTGGAGGATTTGGAATTAGTCCTGGGCGACCTGAAGGACGTGGCCAAGGAACTTAAGGAGCCTCCACCAGGCGGTGTGAAG ATGCCTAATGTACCCAATACACAACCAGCAATAATGAAACCAACAGAGGAACATCCAGCTTATACACAGATTGCAAAGGAACATGCATTG GCCCAAGCTGAACTTCTTAAGCGCCAGGAAGAACTAGAAAGAAAAGCCGCAGAATTAGATCGTCGGGAACGAGAAATGCAAAACCTCAGT CAACATGGTAGAAAAAATAATTGGCCACCTCTTCCTAGCAATTTTCCTGTCGGACCTTGTTTCTATCAGGATTTTTCTGTAGACATTCCT GTAGAATTCCAAAAGACAGTAAAGCTTATGTACTACTTGTGGATGTTCCATGCAGTAACACTGTTTCTAAATATCTTCGGATGCTTGGCT TGGTTTTGTGTTGATTCTGCAAGAGCGGTTGATTTTGGATTGAGTATCCTGTGGTTCTTGCTTTTTACTCCTTGTTCATTTGTCTGTTGG TACAGACCACTTTATGGAGCTTTCAGGAGTGACAGTTCATTTAGATTCTTTGTATTCTTCTTCGTCTATATTTGTCAGTTTGCTGTACAT GTACTCCAAGCTGCAGGATTTCATAACTGGGGCATTGGTGGTTGGATTTCATCCCTTACTGGTCTCAACCAAAATATTCCTGTTGGAATC ATGATGATAATCATAGCAGCACTTTTCACAGCATCAGCAGTCATCTCACTAGTTATGTTCAAAAAAGTACATGGACTATATCGCACAACA GGTGCTAGTTTTGAGAAGGCCCAACAGGAGTTTGCAACAGGTGTGATGTCCAACAAAACTGTCCAGACCGCAGCTGCAAATGCAGCTTCA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_PRR16_ENST00000407149_chr5_119800340_+_SCAMP1_ENST00000538629_chr5_77711344_+_6321nt GAGCCGAGCGCCGCGTCTCGGGAGTTGATGGCAGCACCACTGTGCGGCCGCCCGGCCGAGCGCGGAGCGCAGCCACTCGCCGCTGCCCAG GGAGCGCCCAAGATGTGGGGGGACCGGGGCGGCAGCGGCCGTAGCAGCGCCAGGGACGGGGGCACGCAGCAGCCTCCGCTCGCCCGCCTG TCCTGACCTGCCTCGCTTGCCCCCAAAGAATGTCAGCCAAGTCCAAGGGGAACCCCTCCTCGTCCTGTCCAGCCGAGGGACCGCCGGCAG CCTCCAAAACCAAGGTGAAGGAACAGATCAAGATCATCGTGGAGGATTTGGAATTAGTCCTGGGCGACCTGAAGGACGTGGCCAAGGAAC TTAAGGAGCCTCCACCAGGCGGTGTGAAGATGCCTAATGTACCCAATACACAACCAGCAATAATGAAACCAACAGAGGAACATCCAGCTT ATACACAGATTGCAAAGGAACATGCATTGGCCCAAGCTGAACTTCTTAAGCGCCAGGAAGAACTAGAAAGAAAAGCCGCAGAATTAGATC GTCGGGAACGAGAAATGCAAAACCTCAGTCAACATGGTAGAAAAAATAATTGGCCACCTCTTCCTAGCAATTTTCCTGTCGGACCTTGTT TCTATCAGGATTTTTCTGTAGACATTCCTGTAGAATTCCAAAAGACAGTAAAGCTTATGTACTACTTGTGGATGTTCCATGCAGTAACAC TGTTTCTAAATATCTTCGGATGCTTGGCTTGGTTTTGTGTTGATTCTGCAAGAGCGGTTGATTTTGGATTGAGTATCCTGTGGTTCTTGC TTTTTACTCCTTGTTCATTTGTCTGTTGGTACAGACCACTTTATGGAGCTTTCAGGAGTGACAGTTCATTTAGATTCTTTGTATTCTTCT TCGTCTATATTTGTCAGTTTGCTGTACATGTACTCCAAGCTGCAGGATTTCATAACTGGGGCATTGGTGGTTGGATTTCATCCCTTACTG GTCTCAACCAAAATATTCCTGTTGGAATCATGATGATAATCATAGCAGCACTTTTCACAGCATCAGCAGTCATCTCACTAGTTATGTTCA AAAAAGTACATGGACTATATCGCACAACAGGTGCTAGTTTTGAGAAGGCCCAACAGGAGTTTGCAACAGGTGTGATGTCCAACAAAACTG TCCAGACCGCAGCTGCAAATGCAGCTTCAACTGCAGCATCTAGTGCAGCTCAGAATGCTTTCAAGGGTAACCAGATTTAAGAATCTTCAA ACAATACACTGTTACCTTTTGACTGTACCTTTTTCTCCAGTTACTGTATTCTACAAATATTTTTATGTTCAAAACACACAGTACAGACAG CATGGATATTTCCTGTTCACTTGTGCATGGGCTAAAACCAGGAAAACTTCCTTGTCTTATTACTTTACCTAATAGTTTCTTAATATTTCA GTGCCCCTTGCAGAAAAAATATTACATGCTAAATAAATATTCTCCATATTTTTGGGGGATGACATTCAGTGAATTATTTCAGTGGTGACC CACTGAAAATTAATAATGGTACTTATGATTAAAAACGCATTTAATACTAACTGCAGTAGTTCTTTCAAGAATCTTTAGAGATAAGGATTG CACATTGGAAAAGTAAACCATGTTTCATTCCTTTTTCCCTATTTATATTGAAAGAAATAGGCCAGCAGAGACTTAGGGATTTTAAATTGG CTTGCTTTTTAGCTGTTTCAGTCACCAGTGAAGAGCCTATGTGCATTTTGTAGTAGATAATGTAAAATTTGTCATCTTTTTCTTTTCTTT TTTTTAGAATAGCTGATATTTTGATAACAATCTCTAATTTGCATGGGCACCACATTTCTTATATTAAAAGAATTAGTGTTTTGGCTTCTG TACTGCTTATGGTTGTAGGATTCAGGGGTTAATGGAATCACAGAAATGATATTCTGCAAGAATTTCTTTTAAATAAAAAGTTTGGGGGTG CAATATAAGAAGTTTATATAATATGCAGTACATTATCCAAAAGAGAAGGTAGTTAATGCAGTAGAAAGTAGTGGTAATAATTCCTTTTTA AAAAAATTTCGGTAGTCATATAGTAACATTTTGCTATATGAAAACTTTGGTATATTCTGTGGTTACAACTAAGATTGTGTCTGGCAGCTC TTTTTTGGGGATGTGTGTGTGTGATTTTTAACAGAGGTATTAAAGGCTAGCCTAACTGTTGTCTAAAAAGATTGTACAGTATTTAAGGGA TTTTCCTTTTAGCTTTTCATCTCCAGTGGCATTAAACATAAAAAGACCCTGGCATTTTTTCACATACTTGAATCCCTAAATGCACCTGTC TTTCACTTTTTGAGACAGACTGAATATATCTAAAATTTCCAGCAATAAAAAAAAAAGCATTTAACTTGCACCAAGCAAGAAAATATAAAT ACAGTTAACTGCATTAAGATAATCACGTTAAAATTGTTACTATGCAGCACAGAACTTCATTCTTATAGTATTCTTGGGTTCAACCTTTGA ATCAATTTTACCACTGATTAAATAAATGACTCAAAGACATCTGTAAGTCATGCTGCTGTGTTTTGAAAGTCTTTAACTAAATTAAGATTG CAGAATGATAGTGATTATTCAATTAGATTTTAAGTAAGGATTGTGATATTAGAGGCTGGAAATCCTTATTTTTTAAAAAATCAGATAGGC ATAAATAGTTAAATCACTTTCATTCTCCCCAAACCTGTAGTTACAGAAAAAGTTTTATGCTAGAGGTGGGATGCCAAGTTTTCACTATCC ATGAAGCAGCGCTGCATGTCACTAGGTAACACAGATCCATCCAGATGGTGTTTACATTTGATTTATTTGGGATCTTATTGACATCAGGTA TACTTGGAAGACATTTCTTTTATTCTTCAGCGTATGAATTTAAAGCTATTTTTTGTAAATATTTCTAATCAGCGATAATTTCTACCTATG TTCTCAACCAACTTAGCCAGTTTGTTTTTCAGAGCCTGTAGTCTTATTGGAAATCTATTTTATCAGTGTGCTTTATTGAGTGTGGATTTT GCATACATTCAAAACATTAACCACAAAATACAGCAAGTGCACCTATATTCACCATTAACTTATATCCCAAGTCCATTTTTTCCTGTACAC TACAAACAAAAGATATATTAGAGACTTTTGAAAAATGCTGAAATACTTTGCTTCAGAATTGGAATGTTTATATTATGTAGAAATCTTCAA AGGTAGCATTATTAAATAGCAAAGAATAATTAGAACCCACATATCTTTTTTTGTGTGGATGGGGAAAATGTTTTAAAATCCAGTTATTTA ATATGAGTTTGAGAGAGAAAATTGTTTTTTAAAAATATATGTGCATTGAAATGATGGCAATGCTTATAGTATGATCAAGTATGAAAGGAA CTTTAAATTCTTATATTTACTTTTCTCTCAGTAAATTGTTAAATTTTCACTCAGCAAAAGATTGGCATTTGTTAAGTGTTCTATATTTAG TACTAAAATCACAGTCATGAAATCATAGTCATAAAATGGTCTTCACACAGCAGTCATCCGTGTCATTTATCATTTTGTAATATTAAATTA TGGCAATTTTATTTCAAACTAAAGTTTGAACACCGGAAAGTCATTACTCAGTGATTTGTAATTTGGGACTTGGATTATTTATCTAGAGAT GTTTGTATATTTTGTCAGTAACTAATACTGCGCTGCCATCATGGTGACTGTCATGGTTCTACAGAAATGCCCTCCATGTGTCCCTCTAAT GTTGCATGTTTCAGTGGGTTGGAAGTTTTGTATATTTATTGTATTAACACAGAGTGTCATAAAATAAAATGCTGTTTACTGGATGTTTGT TTGTATAATTTTGAACACTATAATAGCAATTCAGAGACAGACATTGTTAAAGGTTTGATGTATATAGAAATTCCATGTTTGATTTTTTAA AATATGTGTATAAGTCTGTCATGTGCTAAACAAAATAATATGAAAGACCTAGTTAAAAATTCTAACCAATGTAAAATGACCATTTTTCTG TTGCATTAGACCTTTACAGGTAATGGAACATGAGCTTCACCCATATTAAATATTTTGGCCCCTTTAAGGTCAAAATACAGATCATCTAGA AGTTAGATTCAAAATGGAAAACCTATTCATGGCTCAGATTTTTCATTGTGGGTTAAAAATGGGTGTCTCTGTACTAGTATTGTATTTATT CAATTGAACTTGTATTCTGATTTCTATCCTTGCTACCTATTGCTGTTTTATGTACTGATGAAAGTACCTATTTGTGTATATTGGATTTTT CACTTGGTTAGCTAAAGAAGATGTAAAAATATCTAAAATAATGTTCATGGTGAATCTTATTTTGAGAAATACATGTTAAAAAAGGAACAG TATTCTTTATTTTCTGGGTGTTATATTTAAAAAAGCAAGTTTGGATTTTTACACCTAATTTACTAGGAAAATATTTTATTCTGTAATTCA TGTTAAGATTATGTATGGTTTGCATTTTAAGGGGATTTATGTTAGGTTAATTAGTTGTTTCTGTAAATCATTTGTAATAGCATAGTGCTT TTTACTCATTGCTGTATCTTTTTCTGAAAACACTGTTGTTAACATCTAATTCAGTATCCTTATTGGTACAAATCTGTGTTTGGCATGACT GTTTATATACAGAATTTGTTACATTTTGAGCATTTTTTCCCCTGCTTATGTATACCTTAGAGTTACCATGGCTGTCATATACCATTTCAC TATATCTCCTTTCAGTTTTTCCTTAAGGAAAATGTTTAGAGGAATTTGTTCATTTCATGTGATTAAGCCCTTTAGAGATGAAATAAGATT GGTTAATTTTAAAAAAATTGAGGATGGTTAAAAAATAGAAAACACCTTACTTTGATACATTTTAAAGTACAATAGTATACATTTATTTAG AGTAGACTAATGTGTTTAAAACATGAGTTGTTTTAAATACTTTTTTATTGAGCTAAAAAGTTTTATCTCACATATTAAGTATTACAGAAA GTGAAGTATTTTGGCTAGAATTTTAGGGCATATTTTATAAAGCAGCATGCCTGTAATATTGGTGGGTATTTTTAAACTTTAGGACTTTAT CACAGTATGTAGAGAGCTAGAAATAAATCTAGAAACTTTCTAAGCCAGGTATTGCCACTAACCTGTCTTATATAAGCAGATACCTCTTAT TTGAAGATTGTAGGAAAATAGAGAAAGACTGTTCTCCAGTTTTCTCACCCCCGCTGTGGGTTTTATATTTACAATTTAACTTTGGGGTTT GGGTAAGACAAACATTTAATGTATAGGATTTTGGCCAGGTGTGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGTGGGCG GATCACGAGGTCAGGAGATCGAAACCATCCTGGCTAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAAAAAAATTAGCTGAGCAT GGTGGCGGGCGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATGACGTGAACCTGGGAGGCGGAGCTTGCAGTGAGCCGAGA TCTCTCCACTGCACTCCAGCCTGGGCGACAGAGCGAGACTCCATCTCAAGAAAAAAAAAAAAGAATTTTCATTAGTGCTGGCCGTGTTTC AAATGGCAAGGGAACATGGGAACTATCATGTGGCAATGTAGTGAGTGTTAAACTTTGTGTTTGTCCAAATCCTGATTTATTTTTCAGTTC ATATCTTTCTGGGCTTGACATGGCTGATGGTGTAGCTGAAACCCTCCTAACACTAAAAGCCATTTAATCTTTTCTGTAATAGGAGCAGAA AATAGTTAATCATCCACCTAGTAATATAAGATTACTGTGAATATTATCTTCTATACATTAAAACAGTTCTAGTTTGTAGAATAATACCAT ACAAGTTTTATTTTTAAATTCTAGTTATTTTCAGTGCTTACTTAAATGTAATTCTAGAATTCCTCCACAACTTTTAATATTTTGTATGCC AGTGATTCTCAAGATAAATCATGATTGTAGTAGTTGTTACTGTTGGCAGTTTGTAGTAGTATTCAGGTATTTTGGGGATGGGGGAAAACA CCAAAAATCAGTGTCTTTTATCTGGTGATCACTGTGGTATCTACAGTATTCTAGTCTCCTGCACAAAAACTGAACCCACTGGGCCTATGC ATCCCTCACACTTTTTTTCTAGTATAAAAGCAATACATAATGTGTTGTAGAACAATTAAAAATTCAGAAAGTGATACATGAGAAAATAAA |
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FusionGenePPI for PRR16_SCAMP1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| PRR16 | NEDD4, NEDD4L, PPP1CA, APP, PPP1CC, ABI2, SMURF1 | SCAMP1 | ITSN1, SNAP23, SCAMP2, SCAMP1, EPS15, SYNRG, SNAP25, ELAVL1, TP53, UBE3A, FAM208B, ZMIZ2, KRTAP13-1, MOV10, NXF1, CD27, HAX1, NT5E, LYPD3, DLK1, MICA, RTN4, ENPP6, TNFRSF10B, TMEM17, TMEM216, PPM1H, DNAJC13, REEP5, CD70, TTC19 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for PRR16_SCAMP1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for PRR16_SCAMP1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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