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Fusion gene ID: 28823 |
FusionGeneSummary for PRMT2_WRB |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PRMT2_WRB | Fusion gene ID: 28823 | Hgene | Tgene | Gene symbol | PRMT2 | WRB | Gene ID | 3275 | 7485 |
| Gene name | protein arginine methyltransferase 2 | tryptophan rich basic protein | |
| Synonyms | HRMT1L1 | CHD5|GET1 | |
| Cytomap | 21q22.3 | 21q22.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | protein arginine N-methyltransferase 2HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 1HMT1 hnRNP methyltransferase-like 1PRMT2 alphaPRMT2 betaPRMT2 gammahistone-arginine N-methyltransferase PRMT2 | tail-anchored protein insertion receptor WRBcongenital heart disease 5 protein | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | P55345 | O00258 | |
| Ensembl transtripts involved in fusion gene | ENST00000355680, ENST00000397638, ENST00000291705, ENST00000458387, ENST00000451211, ENST00000397637, ENST00000334494, ENST00000397628, ENST00000440086, ENST00000491389, | ENST00000333781, ENST00000541890, ENST00000398753, ENST00000380708, ENST00000466787, | |
| Fusion gene scores | * DoF score | 6 X 6 X 4=144 | 5 X 4 X 4=80 |
| # samples | 6 | 5 | |
| ** MAII score | log2(6/144*10)=-1.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(5/80*10)=-0.678071905112638 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: PRMT2 [Title/Abstract] AND WRB [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | PRMT2 | GO:0016571 | histone methylation | 19405910 |
| Hgene | PRMT2 | GO:0032088 | negative regulation of NF-kappaB transcription factor activity | 16648481 |
| Hgene | PRMT2 | GO:0045892 | negative regulation of transcription, DNA-templated | 16648481 |
| Hgene | PRMT2 | GO:0045893 | positive regulation of transcription, DNA-templated | 12039952 |
| Hgene | PRMT2 | GO:0060765 | regulation of androgen receptor signaling pathway | 17587566 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | HNSC | TCGA-D6-A4ZB-01A | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000355680 | ENST00000333781 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| In-frame | ENST00000355680 | ENST00000541890 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| In-frame | ENST00000355680 | ENST00000398753 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| In-frame | ENST00000355680 | ENST00000380708 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| 5CDS-3UTR | ENST00000355680 | ENST00000466787 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| In-frame | ENST00000397638 | ENST00000333781 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| In-frame | ENST00000397638 | ENST00000541890 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| In-frame | ENST00000397638 | ENST00000398753 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| In-frame | ENST00000397638 | ENST00000380708 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| 5CDS-3UTR | ENST00000397638 | ENST00000466787 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| In-frame | ENST00000291705 | ENST00000333781 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| In-frame | ENST00000291705 | ENST00000541890 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| In-frame | ENST00000291705 | ENST00000398753 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| In-frame | ENST00000291705 | ENST00000380708 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| 5CDS-3UTR | ENST00000291705 | ENST00000466787 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| In-frame | ENST00000458387 | ENST00000333781 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| In-frame | ENST00000458387 | ENST00000541890 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| In-frame | ENST00000458387 | ENST00000398753 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| In-frame | ENST00000458387 | ENST00000380708 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| 5CDS-3UTR | ENST00000458387 | ENST00000466787 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| In-frame | ENST00000451211 | ENST00000333781 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| In-frame | ENST00000451211 | ENST00000541890 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| In-frame | ENST00000451211 | ENST00000398753 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| In-frame | ENST00000451211 | ENST00000380708 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| 5CDS-3UTR | ENST00000451211 | ENST00000466787 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| In-frame | ENST00000397637 | ENST00000333781 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| In-frame | ENST00000397637 | ENST00000541890 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| In-frame | ENST00000397637 | ENST00000398753 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| In-frame | ENST00000397637 | ENST00000380708 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| 5CDS-3UTR | ENST00000397637 | ENST00000466787 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| In-frame | ENST00000334494 | ENST00000333781 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| In-frame | ENST00000334494 | ENST00000541890 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| In-frame | ENST00000334494 | ENST00000398753 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| In-frame | ENST00000334494 | ENST00000380708 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| 5CDS-3UTR | ENST00000334494 | ENST00000466787 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| Frame-shift | ENST00000397628 | ENST00000333781 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| Frame-shift | ENST00000397628 | ENST00000541890 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| Frame-shift | ENST00000397628 | ENST00000398753 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| Frame-shift | ENST00000397628 | ENST00000380708 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| 5CDS-3UTR | ENST00000397628 | ENST00000466787 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| In-frame | ENST00000440086 | ENST00000333781 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| In-frame | ENST00000440086 | ENST00000541890 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| In-frame | ENST00000440086 | ENST00000398753 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| In-frame | ENST00000440086 | ENST00000380708 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| 5CDS-3UTR | ENST00000440086 | ENST00000466787 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| 3UTR-3CDS | ENST00000491389 | ENST00000333781 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| 3UTR-3CDS | ENST00000491389 | ENST00000541890 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| 3UTR-3CDS | ENST00000491389 | ENST00000398753 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| 3UTR-3CDS | ENST00000491389 | ENST00000380708 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
| 3UTR-3UTR | ENST00000491389 | ENST00000466787 | PRMT2 | chr21 | 48069651 | + | WRB | chr21 | 40762624 | + |
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FusionProtFeatures for PRMT2_WRB |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| PRMT2 | WRB |
| Receptor for ASNA1/TRC40-mediated insertion of tail-anchored (TA) proteins into the ER membrane.{ECO:0000269|PubMed:21444755}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | PRMT2 | chr21:48069651 | chr21:40762624 | ENST00000334494 | + | 6 | 7 | 30_89 | 218 | 285 | Domain | SH3 |
| Hgene | PRMT2 | chr21:48069651 | chr21:40762624 | ENST00000355680 | + | 7 | 12 | 30_89 | 218 | 434 | Domain | SH3 |
| Hgene | PRMT2 | chr21:48069651 | chr21:40762624 | ENST00000397637 | + | 6 | 11 | 30_89 | 218 | 434 | Domain | SH3 |
| Hgene | PRMT2 | chr21:48069651 | chr21:40762624 | ENST00000397638 | + | 6 | 11 | 30_89 | 218 | 434 | Domain | SH3 |
| Hgene | PRMT2 | chr21:48069651 | chr21:40762624 | ENST00000440086 | + | 6 | 9 | 30_89 | 218 | 332 | Domain | SH3 |
| Tgene | >WRB | chr21:48069651 | chr21:40762624 | ENST00000333781 | + | 0 | 5 | 39_94 | 34 | 175 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >WRB | chr21:48069651 | chr21:40762624 | ENST00000380708 | + | 0 | 5 | 39_94 | 0 | 141 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >WRB | chr21:48069651 | chr21:40762624 | ENST00000398753 | + | 0 | 5 | 39_94 | 0 | 141 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >WRB | chr21:48069651 | chr21:40762624 | ENST00000333781 | + | 0 | 5 | 121_148 | 34 | 175 | Topological domain | Lumenal |
| Tgene | >WRB | chr21:48069651 | chr21:40762624 | ENST00000333781 | + | 0 | 5 | 170_174 | 34 | 175 | Topological domain | Cytoplasmic |
| Tgene | >WRB | chr21:48069651 | chr21:40762624 | ENST00000380708 | + | 0 | 5 | 121_148 | 0 | 141 | Topological domain | Lumenal |
| Tgene | >WRB | chr21:48069651 | chr21:40762624 | ENST00000380708 | + | 0 | 5 | 170_174 | 0 | 141 | Topological domain | Cytoplasmic |
| Tgene | >WRB | chr21:48069651 | chr21:40762624 | ENST00000380708 | + | 0 | 5 | 1_8 | 0 | 141 | Topological domain | Lumenal |
| Tgene | >WRB | chr21:48069651 | chr21:40762624 | ENST00000380708 | + | 0 | 5 | 30_99 | 0 | 141 | Topological domain | Cytoplasmic |
| Tgene | >WRB | chr21:48069651 | chr21:40762624 | ENST00000398753 | + | 0 | 5 | 121_148 | 0 | 141 | Topological domain | Lumenal |
| Tgene | >WRB | chr21:48069651 | chr21:40762624 | ENST00000398753 | + | 0 | 5 | 170_174 | 0 | 141 | Topological domain | Cytoplasmic |
| Tgene | >WRB | chr21:48069651 | chr21:40762624 | ENST00000398753 | + | 0 | 5 | 1_8 | 0 | 141 | Topological domain | Lumenal |
| Tgene | >WRB | chr21:48069651 | chr21:40762624 | ENST00000398753 | + | 0 | 5 | 30_99 | 0 | 141 | Topological domain | Cytoplasmic |
| Tgene | >WRB | chr21:48069651 | chr21:40762624 | ENST00000333781 | + | 0 | 5 | 100_120 | 34 | 175 | Transmembrane | Helical |
| Tgene | >WRB | chr21:48069651 | chr21:40762624 | ENST00000333781 | + | 0 | 5 | 149_169 | 34 | 175 | Transmembrane | Helical |
| Tgene | >WRB | chr21:48069651 | chr21:40762624 | ENST00000380708 | + | 0 | 5 | 100_120 | 0 | 141 | Transmembrane | Helical |
| Tgene | >WRB | chr21:48069651 | chr21:40762624 | ENST00000380708 | + | 0 | 5 | 149_169 | 0 | 141 | Transmembrane | Helical |
| Tgene | >WRB | chr21:48069651 | chr21:40762624 | ENST00000380708 | + | 0 | 5 | 9_29 | 0 | 141 | Transmembrane | Helical |
| Tgene | >WRB | chr21:48069651 | chr21:40762624 | ENST00000398753 | + | 0 | 5 | 100_120 | 0 | 141 | Transmembrane | Helical |
| Tgene | >WRB | chr21:48069651 | chr21:40762624 | ENST00000398753 | + | 0 | 5 | 149_169 | 0 | 141 | Transmembrane | Helical |
| Tgene | >WRB | chr21:48069651 | chr21:40762624 | ENST00000398753 | + | 0 | 5 | 9_29 | 0 | 141 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >PRMT2 | chr21:48069651 | chr21:40762624 | ENST00000334494 | + | 6 | 7 | 99_432 | 218 | 285 | Domain | SAM-dependent MTase PRMT-type |
| Hgene | >PRMT2 | chr21:48069651 | chr21:40762624 | ENST00000355680 | + | 7 | 12 | 99_432 | 218 | 434 | Domain | SAM-dependent MTase PRMT-type |
| Hgene | >PRMT2 | chr21:48069651 | chr21:40762624 | ENST00000397637 | + | 6 | 11 | 99_432 | 218 | 434 | Domain | SAM-dependent MTase PRMT-type |
| Hgene | >PRMT2 | chr21:48069651 | chr21:40762624 | ENST00000397638 | + | 6 | 11 | 99_432 | 218 | 434 | Domain | SAM-dependent MTase PRMT-type |
| Hgene | >PRMT2 | chr21:48069651 | chr21:40762624 | ENST00000440086 | + | 6 | 9 | 99_432 | 218 | 332 | Domain | SAM-dependent MTase PRMT-type |
| Tgene | WRB | chr21:48069651 | chr21:40762624 | ENST00000333781 | + | 0 | 5 | 1_8 | 34 | 175 | Topological domain | Lumenal |
| Tgene | WRB | chr21:48069651 | chr21:40762624 | ENST00000333781 | + | 0 | 5 | 30_99 | 34 | 175 | Topological domain | Cytoplasmic |
| Tgene | WRB | chr21:48069651 | chr21:40762624 | ENST00000333781 | + | 0 | 5 | 9_29 | 34 | 175 | Transmembrane | Helical |
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FusionGeneSequence for PRMT2_WRB |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_PRMT2_ENST00000355680_chr21_48069651_+_WRB_ENST00000333781_chr21_40762624_+_359aa MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLV LQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLMSRVLQKDAEQESQMRAEIQDMKQELSTVNMMDEFARYARLERKINKMTDKL >In-frame_PRMT2_ENST00000355680_chr21_48069651_+_WRB_ENST00000541890_chr21_40762624_+_357aa MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLV LQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLMSRVLQKDAEQESQMRAEIQDMKQELSTVNMMDEFARYARLERKINKMTDKL >In-frame_PRMT2_ENST00000355680_chr21_48069651_+_WRB_ENST00000398753_chr21_40762624_+_359aa MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLV LQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLMSRVLQKDAEQESQMRAEIQDMKQELSTVNMMDEFARYARLERKINKMTDKL >In-frame_PRMT2_ENST00000355680_chr21_48069651_+_WRB_ENST00000380708_chr21_40762624_+_359aa MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLV LQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLMSRVLQKDAEQESQMRAEIQDMKQELSTVNMMDEFARYARLERKINKMTDKL >In-frame_PRMT2_ENST00000397638_chr21_48069651_+_WRB_ENST00000333781_chr21_40762624_+_359aa MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLV LQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLMSRVLQKDAEQESQMRAEIQDMKQELSTVNMMDEFARYARLERKINKMTDKL >In-frame_PRMT2_ENST00000397638_chr21_48069651_+_WRB_ENST00000541890_chr21_40762624_+_357aa MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLV LQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLMSRVLQKDAEQESQMRAEIQDMKQELSTVNMMDEFARYARLERKINKMTDKL >In-frame_PRMT2_ENST00000397638_chr21_48069651_+_WRB_ENST00000398753_chr21_40762624_+_359aa MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLV LQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLMSRVLQKDAEQESQMRAEIQDMKQELSTVNMMDEFARYARLERKINKMTDKL >In-frame_PRMT2_ENST00000397638_chr21_48069651_+_WRB_ENST00000380708_chr21_40762624_+_359aa MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLV LQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLMSRVLQKDAEQESQMRAEIQDMKQELSTVNMMDEFARYARLERKINKMTDKL >In-frame_PRMT2_ENST00000291705_chr21_48069651_+_WRB_ENST00000333781_chr21_40762624_+_359aa MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLV LQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLMSRVLQKDAEQESQMRAEIQDMKQELSTVNMMDEFARYARLERKINKMTDKL >In-frame_PRMT2_ENST00000291705_chr21_48069651_+_WRB_ENST00000541890_chr21_40762624_+_357aa MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLV LQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLMSRVLQKDAEQESQMRAEIQDMKQELSTVNMMDEFARYARLERKINKMTDKL >In-frame_PRMT2_ENST00000291705_chr21_48069651_+_WRB_ENST00000398753_chr21_40762624_+_359aa MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLV LQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLMSRVLQKDAEQESQMRAEIQDMKQELSTVNMMDEFARYARLERKINKMTDKL >In-frame_PRMT2_ENST00000291705_chr21_48069651_+_WRB_ENST00000380708_chr21_40762624_+_359aa MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLV LQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLMSRVLQKDAEQESQMRAEIQDMKQELSTVNMMDEFARYARLERKINKMTDKL >In-frame_PRMT2_ENST00000458387_chr21_48069651_+_WRB_ENST00000333781_chr21_40762624_+_359aa MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLV LQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLMSRVLQKDAEQESQMRAEIQDMKQELSTVNMMDEFARYARLERKINKMTDKL >In-frame_PRMT2_ENST00000458387_chr21_48069651_+_WRB_ENST00000541890_chr21_40762624_+_357aa MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLV LQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLMSRVLQKDAEQESQMRAEIQDMKQELSTVNMMDEFARYARLERKINKMTDKL >In-frame_PRMT2_ENST00000458387_chr21_48069651_+_WRB_ENST00000398753_chr21_40762624_+_359aa MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLV LQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLMSRVLQKDAEQESQMRAEIQDMKQELSTVNMMDEFARYARLERKINKMTDKL >In-frame_PRMT2_ENST00000458387_chr21_48069651_+_WRB_ENST00000380708_chr21_40762624_+_359aa MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLV LQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLMSRVLQKDAEQESQMRAEIQDMKQELSTVNMMDEFARYARLERKINKMTDKL >In-frame_PRMT2_ENST00000451211_chr21_48069651_+_WRB_ENST00000333781_chr21_40762624_+_359aa MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLV LQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLMSRVLQKDAEQESQMRAEIQDMKQELSTVNMMDEFARYARLERKINKMTDKL >In-frame_PRMT2_ENST00000451211_chr21_48069651_+_WRB_ENST00000541890_chr21_40762624_+_357aa MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLV LQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLMSRVLQKDAEQESQMRAEIQDMKQELSTVNMMDEFARYARLERKINKMTDKL >In-frame_PRMT2_ENST00000451211_chr21_48069651_+_WRB_ENST00000398753_chr21_40762624_+_359aa MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLV LQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLMSRVLQKDAEQESQMRAEIQDMKQELSTVNMMDEFARYARLERKINKMTDKL >In-frame_PRMT2_ENST00000451211_chr21_48069651_+_WRB_ENST00000380708_chr21_40762624_+_359aa MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLV LQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLMSRVLQKDAEQESQMRAEIQDMKQELSTVNMMDEFARYARLERKINKMTDKL >In-frame_PRMT2_ENST00000397637_chr21_48069651_+_WRB_ENST00000333781_chr21_40762624_+_359aa MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLV LQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLMSRVLQKDAEQESQMRAEIQDMKQELSTVNMMDEFARYARLERKINKMTDKL >In-frame_PRMT2_ENST00000397637_chr21_48069651_+_WRB_ENST00000541890_chr21_40762624_+_357aa MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLV LQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLMSRVLQKDAEQESQMRAEIQDMKQELSTVNMMDEFARYARLERKINKMTDKL >In-frame_PRMT2_ENST00000397637_chr21_48069651_+_WRB_ENST00000398753_chr21_40762624_+_359aa MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLV LQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLMSRVLQKDAEQESQMRAEIQDMKQELSTVNMMDEFARYARLERKINKMTDKL >In-frame_PRMT2_ENST00000397637_chr21_48069651_+_WRB_ENST00000380708_chr21_40762624_+_359aa MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLV LQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLMSRVLQKDAEQESQMRAEIQDMKQELSTVNMMDEFARYARLERKINKMTDKL >In-frame_PRMT2_ENST00000334494_chr21_48069651_+_WRB_ENST00000333781_chr21_40762624_+_359aa MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLV LQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLMSRVLQKDAEQESQMRAEIQDMKQELSTVNMMDEFARYARLERKINKMTDKL >In-frame_PRMT2_ENST00000334494_chr21_48069651_+_WRB_ENST00000541890_chr21_40762624_+_357aa MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLV LQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLMSRVLQKDAEQESQMRAEIQDMKQELSTVNMMDEFARYARLERKINKMTDKL >In-frame_PRMT2_ENST00000334494_chr21_48069651_+_WRB_ENST00000398753_chr21_40762624_+_359aa MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLV LQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLMSRVLQKDAEQESQMRAEIQDMKQELSTVNMMDEFARYARLERKINKMTDKL >In-frame_PRMT2_ENST00000334494_chr21_48069651_+_WRB_ENST00000380708_chr21_40762624_+_359aa MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLV LQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLMSRVLQKDAEQESQMRAEIQDMKQELSTVNMMDEFARYARLERKINKMTDKL >In-frame_PRMT2_ENST00000440086_chr21_48069651_+_WRB_ENST00000333781_chr21_40762624_+_359aa MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLV LQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLMSRVLQKDAEQESQMRAEIQDMKQELSTVNMMDEFARYARLERKINKMTDKL >In-frame_PRMT2_ENST00000440086_chr21_48069651_+_WRB_ENST00000541890_chr21_40762624_+_357aa MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLV LQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLMSRVLQKDAEQESQMRAEIQDMKQELSTVNMMDEFARYARLERKINKMTDKL >In-frame_PRMT2_ENST00000440086_chr21_48069651_+_WRB_ENST00000398753_chr21_40762624_+_359aa MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLV LQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLMSRVLQKDAEQESQMRAEIQDMKQELSTVNMMDEFARYARLERKINKMTDKL >In-frame_PRMT2_ENST00000440086_chr21_48069651_+_WRB_ENST00000380708_chr21_40762624_+_359aa MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAVYAVEASEMAQHTGQLV LQNGFADIITVYQQKVEDVVLPEKVDVLVSEWMGTCLLMSRVLQKDAEQESQMRAEIQDMKQELSTVNMMDEFARYARLERKINKMTDKL |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_PRMT2_ENST00000355680_chr21_48069651_+_WRB_ENST00000333781_chr21_40762624_+_1077nt ATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTA CAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTG AGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAG TACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCA CGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATC ATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTC CTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCT GAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATG AAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTC AAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATG ATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCT >In-frame_PRMT2_ENST00000355680_chr21_48069651_+_WRB_ENST00000541890_chr21_40762624_+_1071nt ATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTA CAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTG AGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAG TACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCA CGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATC ATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTC CTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCT GAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATG AAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTC AAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATG ATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCT >In-frame_PRMT2_ENST00000355680_chr21_48069651_+_WRB_ENST00000398753_chr21_40762624_+_1077nt ATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTA CAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTG AGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAG TACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCA CGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATC ATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTC CTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCT GAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATG AAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTC AAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATG ATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCT >In-frame_PRMT2_ENST00000355680_chr21_48069651_+_WRB_ENST00000380708_chr21_40762624_+_1077nt ATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTA CAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTG AGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAG TACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCA CGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATC ATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTC CTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCT GAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATG AAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTC AAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATG ATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCT >In-frame_PRMT2_ENST00000397638_chr21_48069651_+_WRB_ENST00000333781_chr21_40762624_+_1077nt ATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTA CAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTG AGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAG TACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCA CGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATC ATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTC CTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCT GAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATG AAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTC AAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATG ATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCT >In-frame_PRMT2_ENST00000397638_chr21_48069651_+_WRB_ENST00000541890_chr21_40762624_+_1071nt ATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTA CAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTG AGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAG TACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCA CGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATC ATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTC CTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCT GAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATG AAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTC AAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATG ATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCT >In-frame_PRMT2_ENST00000397638_chr21_48069651_+_WRB_ENST00000398753_chr21_40762624_+_1077nt ATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTA CAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTG AGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAG TACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCA CGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATC ATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTC CTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCT GAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATG AAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTC AAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATG ATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCT >In-frame_PRMT2_ENST00000397638_chr21_48069651_+_WRB_ENST00000380708_chr21_40762624_+_1077nt ATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTA CAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTG AGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAG TACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCA CGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATC ATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTC CTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCT GAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATG AAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTC AAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATG ATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCT >In-frame_PRMT2_ENST00000291705_chr21_48069651_+_WRB_ENST00000333781_chr21_40762624_+_1077nt ATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTA CAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTG AGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAG TACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCA CGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATC ATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTC CTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCT GAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATG AAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTC AAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATG ATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCT >In-frame_PRMT2_ENST00000291705_chr21_48069651_+_WRB_ENST00000541890_chr21_40762624_+_1071nt ATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTA CAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTG AGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAG TACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCA CGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATC ATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTC CTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCT GAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATG AAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTC AAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATG ATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCT >In-frame_PRMT2_ENST00000291705_chr21_48069651_+_WRB_ENST00000398753_chr21_40762624_+_1077nt ATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTA CAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTG AGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAG TACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCA CGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATC ATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTC CTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCT GAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATG AAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTC AAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATG ATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCT >In-frame_PRMT2_ENST00000291705_chr21_48069651_+_WRB_ENST00000380708_chr21_40762624_+_1077nt ATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTA CAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTG AGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAG TACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCA CGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATC ATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTC CTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCT GAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATG AAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTC AAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATG ATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCT >In-frame_PRMT2_ENST00000458387_chr21_48069651_+_WRB_ENST00000333781_chr21_40762624_+_1077nt ATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTA CAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTG AGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAG TACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCA CGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATC ATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTC CTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCT GAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATG AAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTC AAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATG ATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCT >In-frame_PRMT2_ENST00000458387_chr21_48069651_+_WRB_ENST00000541890_chr21_40762624_+_1071nt ATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTA CAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTG AGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAG TACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCA CGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATC ATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTC CTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCT GAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATG AAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTC AAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATG ATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCT >In-frame_PRMT2_ENST00000458387_chr21_48069651_+_WRB_ENST00000398753_chr21_40762624_+_1077nt ATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTA CAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTG AGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAG TACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCA CGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATC ATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTC CTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCT GAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATG AAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTC AAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATG ATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCT >In-frame_PRMT2_ENST00000458387_chr21_48069651_+_WRB_ENST00000380708_chr21_40762624_+_1077nt ATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTA CAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTG AGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAG TACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCA CGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATC ATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTC CTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCT GAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATG AAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTC AAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATG ATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCT >In-frame_PRMT2_ENST00000451211_chr21_48069651_+_WRB_ENST00000333781_chr21_40762624_+_1077nt ATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTA CAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTG AGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAG TACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCA CGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATC ATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTC CTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCT GAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATG AAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTC AAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATG ATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCT >In-frame_PRMT2_ENST00000451211_chr21_48069651_+_WRB_ENST00000541890_chr21_40762624_+_1071nt ATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTA CAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTG AGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAG TACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCA CGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATC ATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTC CTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCT GAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATG AAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTC AAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATG ATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCT >In-frame_PRMT2_ENST00000451211_chr21_48069651_+_WRB_ENST00000398753_chr21_40762624_+_1077nt ATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTA CAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTG AGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAG TACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCA CGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATC ATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTC CTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCT GAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATG AAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTC AAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATG ATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCT >In-frame_PRMT2_ENST00000451211_chr21_48069651_+_WRB_ENST00000380708_chr21_40762624_+_1077nt ATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTA CAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTG AGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAG TACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCA CGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATC ATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTC CTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCT GAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATG AAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTC AAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATG ATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCT >In-frame_PRMT2_ENST00000397637_chr21_48069651_+_WRB_ENST00000333781_chr21_40762624_+_1077nt ATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTA CAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTG AGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAG TACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCA CGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATC ATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTC CTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCT GAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATG AAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTC AAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATG ATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCT >In-frame_PRMT2_ENST00000397637_chr21_48069651_+_WRB_ENST00000541890_chr21_40762624_+_1071nt ATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTA CAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTG AGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAG TACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCA CGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATC ATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTC CTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCT GAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATG AAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTC AAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATG ATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCT >In-frame_PRMT2_ENST00000397637_chr21_48069651_+_WRB_ENST00000398753_chr21_40762624_+_1077nt ATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTA CAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTG AGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAG TACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCA CGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATC ATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTC CTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCT GAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATG AAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTC AAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATG ATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCT >In-frame_PRMT2_ENST00000397637_chr21_48069651_+_WRB_ENST00000380708_chr21_40762624_+_1077nt ATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTA CAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTG AGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAG TACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCA CGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATC ATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTC CTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCT GAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATG AAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTC AAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATG ATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCT >In-frame_PRMT2_ENST00000334494_chr21_48069651_+_WRB_ENST00000333781_chr21_40762624_+_1077nt ATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTA CAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTG AGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAG TACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCA CGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATC ATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTC CTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCT GAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATG AAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTC AAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATG ATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCT >In-frame_PRMT2_ENST00000334494_chr21_48069651_+_WRB_ENST00000541890_chr21_40762624_+_1071nt ATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTA CAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTG AGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAG TACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCA CGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATC ATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTC CTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCT GAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATG AAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTC AAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATG ATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCT >In-frame_PRMT2_ENST00000334494_chr21_48069651_+_WRB_ENST00000398753_chr21_40762624_+_1077nt ATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTA CAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTG AGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAG TACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCA CGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATC ATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTC CTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCT GAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATG AAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTC AAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATG ATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCT >In-frame_PRMT2_ENST00000334494_chr21_48069651_+_WRB_ENST00000380708_chr21_40762624_+_1077nt ATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTA CAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTG AGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAG TACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCA CGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATC ATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTC CTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCT GAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATG AAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTC AAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATG ATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCT >In-frame_PRMT2_ENST00000440086_chr21_48069651_+_WRB_ENST00000333781_chr21_40762624_+_1077nt ATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTA CAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTG AGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAG TACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCA CGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATC ATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTC CTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCT GAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATG AAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTC AAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATG ATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCT >In-frame_PRMT2_ENST00000440086_chr21_48069651_+_WRB_ENST00000541890_chr21_40762624_+_1071nt ATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTA CAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTG AGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAG TACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCA CGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATC ATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTC CTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCT GAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATG AAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTC AAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATG ATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCT >In-frame_PRMT2_ENST00000440086_chr21_48069651_+_WRB_ENST00000398753_chr21_40762624_+_1077nt ATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTA CAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTG AGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAG TACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCA CGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATC ATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTC CTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCT GAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATG AAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTC AAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATG ATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCT >In-frame_PRMT2_ENST00000440086_chr21_48069651_+_WRB_ENST00000380708_chr21_40762624_+_1077nt ATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTA CAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTG AGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAG TACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCA CGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATC ATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTC CTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCT GAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATG AAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTC AAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATG ATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_PRMT2_ENST00000355680_chr21_48069651_+_WRB_ENST00000333781_chr21_40762624_+_2789nt ACTTATCCAGAAGAAAGGCAGAGGGCGCACACTGCGCAGCGCGGATGGGAAAGTTAACTGAATTATTTGCGGGAAGACAGAGGAGGTGGG GGGTCCCCCAAGCCCCAGCCATTTTGTGGCTCGTAGGGGTTGTCGCTTCCCAAGCCGTGAATGGCCCAAACCCGCCCCCCGCCCCAGGTC GGACTCCTGCCCCGCGCCCCTCTGGGTCGGACCCCAAGCCGAGCCCCCCAACCCCGCGGCTGGGCTGGGCGATTGGGGACGAGCTCCACA CATGGAGAACCTGGCCTCGCCTCGCAAGACCGCGGGACGCGCAGATGTGAAGTGCGCCTGCGCGGGGCGCAGCCCCAGCTGCAGACGATC TGTGAGCGACGCGCCGGCGCAAGTCGAGGGCGGTGGCTTGGCTTCCCTGGAATGGGGGACGTCTTAGGACTGCGCCTGCGCGGGGCGCCG GGCCCTGGGCGGGGCCTTCCCGGCTGACGGCCTGCGTGCACTGCGCTTGCGCGGGTTGAGGGCGGTGGCTCAGGCTCCTGGAAAGGACCG TCCACCCCTCCGCGCTGGCGGTGTGGACGCGGAACTCAGCGGAGAAACGCGATTGAGAGCAGTGTGTGGATTACACTATCACTGGAAAAA TACGAATTGAGAAGAAGGAAAAGACTGGAAGATGCAGACCTTGGTTCCTGTTAGTGGAAACACTGTAAGGTCCCAGAAATGGAAAAGAAA ATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAG CCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAG ACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGT GGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTAT GGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTG ACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCG GTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTCCTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTG GAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCTGAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGAC GCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATGAAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATAT GCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTCAAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGG GTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATGATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCG AGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCTACTAGAGTAGCAGGTGGTGTTGGAATTACCTGTTGGATTTTAGTCTGT AACAAAGTTGTCGCTATTGTGCTTCATCCGTTCAGCTGAACAGGAGGATGGATACAGCCGCGAGGCTAAAAAACGGATTTCCTCTTCCTA GCTTAAAATCTGATTTACACTGTTTTGTTTTTTAAGAAACAAAAGTGCATAGTTTAGATTTTTTTTTTGTTGAATATGTTTGTTCTTGGA CTTTATGAGAGAGTCTTATAAGAATCACGATTTTCTACACCTGTCATTGAGCCAAGAAAGTCCAGTTTATGACACGTATGTACTAGTGAA CACCGTCCTCGATCTGTACGAAATGTGAAATGTTTAGGGACATCTCCATGCTGTCACTTGTGATTTGCCCTCTTATGTATTTTGGTCATA TTGCCAACTGGAAAGTCAAAATTTTCTAACAACTTTAAGTAAGTTCTTTGAAGACTTAGTGCTGTTTTTAATCCAGTTTAGAAAGTAACT TAATTTTAATACCACTACTAAAAATTCGAAAATTTCTTCTTTAATCACATTCAATATGGTTAAAAGAACAACACTAATTGACATTGCGTG GGCTTTTTCTCCCTTTGTTTAAAATGTCATTTGTTGAGCAAGAGTTGTATAGTATTATCTACTTACTTGAGGCTGTTAATTTTTCATTAC AGTGTTTTGTAAATGTATCCACGAGACCATGATGCATTGTTTTGTGCTCAACTTGTGTTTTGTATTTAAAGCATTTTGAATGAAGTGTAT TTTATAAGCATTTAATATTTATGCTCTTTAGAATGGAACACAGAAAACAAACCTTATAAGTCCTGATTAATCTGAACCAATAACCTGTGT GGCCTACAAAGTATAATTCTATTAAATGTTCCTTAAAACACTTTTTTCTAATTAAAATCTTTGCAAATGCTTGTGTAACTTCCTGCCTTA >In-frame_PRMT2_ENST00000355680_chr21_48069651_+_WRB_ENST00000541890_chr21_40762624_+_2675nt ACTTATCCAGAAGAAAGGCAGAGGGCGCACACTGCGCAGCGCGGATGGGAAAGTTAACTGAATTATTTGCGGGAAGACAGAGGAGGTGGG GGGTCCCCCAAGCCCCAGCCATTTTGTGGCTCGTAGGGGTTGTCGCTTCCCAAGCCGTGAATGGCCCAAACCCGCCCCCCGCCCCAGGTC GGACTCCTGCCCCGCGCCCCTCTGGGTCGGACCCCAAGCCGAGCCCCCCAACCCCGCGGCTGGGCTGGGCGATTGGGGACGAGCTCCACA CATGGAGAACCTGGCCTCGCCTCGCAAGACCGCGGGACGCGCAGATGTGAAGTGCGCCTGCGCGGGGCGCAGCCCCAGCTGCAGACGATC TGTGAGCGACGCGCCGGCGCAAGTCGAGGGCGGTGGCTTGGCTTCCCTGGAATGGGGGACGTCTTAGGACTGCGCCTGCGCGGGGCGCCG GGCCCTGGGCGGGGCCTTCCCGGCTGACGGCCTGCGTGCACTGCGCTTGCGCGGGTTGAGGGCGGTGGCTCAGGCTCCTGGAAAGGACCG TCCACCCCTCCGCGCTGGCGGTGTGGACGCGGAACTCAGCGGAGAAACGCGATTGAGAGCAGTGTGTGGATTACACTATCACTGGAAAAA TACGAATTGAGAAGAAGGAAAAGACTGGAAGATGCAGACCTTGGTTCCTGTTAGTGGAAACACTGTAAGGTCCCAGAAATGGAAAAGAAA ATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAG CCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAG ACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGT GGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTAT GGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTG ACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCG GTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTCCTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTG GAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCTGAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGAC GCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATGAAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATAT GCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTCAAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGG GTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATGATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCG AGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCTACTAGAGTAGCAGTATTCTCCAGCAGTATTTGGACTTCCAAATGTTTC TCTTCCCCTGATAAATCTATATTAGAAAAATAGGCAATTTAGTGCTGTTTAAAATGAATGGATCTCTATTTCAAGATGGCATGTCTAGTA CACTTACGTGCACCGCCTCACAAGCACACTGAAATGACAGAAAAGGACACTATGAATTAGGACAATGGACTGAAAAATAAGCAGAAAATT TAAACACACCAGTGACCACAGTGCAACTGCAACTGACGATCAGTTTCCACCAAACTGCAACAGAGAGAGTGGCTTTGCCGTCTGGGCCAG CTGAGGACTCTCCTTGGAACCCAAAGAAGCAGTTTGTTTCCACCTACTCCCAAGAGCTGAAGATTATAAGCCAGAAGCAAACAAAGGCAG GCAAGGAAATTTGAGGTTGTTGCATCTGGAAGTAAACATGTAGCTACTTCTTCTAATAAAACAGAGTTCTATCTTTTGATTTGGTCTGGA CACCTGGAGGTCAGCAACCGAGAGCAGGAAGGAGGCACAGCAACAACAGAACAACAACAAGAGGCTGCGACAGGGGCGGCGTGGGTCAAA AGGAAGCAACCTGGAGGACGGTCCTCCTTGCGGCTTGGAGCAGAGCTTCAGGTTGGGCACCACGACAGAGCTGGGCCAGAAGTCTAACAC AGCCTGTTTGGAACACAACCCGGGATACTTGTGTGGTTGGGTTCAGTCAGTCAAGGGAAACAAGAAGCTAACCCGTGGCTGGGAGTGTTC ATGCAATGCTCGTGGAATACTCAGCGCAAAGCCTGCCCGCAAGCACAAAGGGTATCAAGGAAGAGTTAAATGGGAAGTTGGGTCATGGTG >In-frame_PRMT2_ENST00000355680_chr21_48069651_+_WRB_ENST00000398753_chr21_40762624_+_2016nt ACTTATCCAGAAGAAAGGCAGAGGGCGCACACTGCGCAGCGCGGATGGGAAAGTTAACTGAATTATTTGCGGGAAGACAGAGGAGGTGGG GGGTCCCCCAAGCCCCAGCCATTTTGTGGCTCGTAGGGGTTGTCGCTTCCCAAGCCGTGAATGGCCCAAACCCGCCCCCCGCCCCAGGTC GGACTCCTGCCCCGCGCCCCTCTGGGTCGGACCCCAAGCCGAGCCCCCCAACCCCGCGGCTGGGCTGGGCGATTGGGGACGAGCTCCACA CATGGAGAACCTGGCCTCGCCTCGCAAGACCGCGGGACGCGCAGATGTGAAGTGCGCCTGCGCGGGGCGCAGCCCCAGCTGCAGACGATC TGTGAGCGACGCGCCGGCGCAAGTCGAGGGCGGTGGCTTGGCTTCCCTGGAATGGGGGACGTCTTAGGACTGCGCCTGCGCGGGGCGCCG GGCCCTGGGCGGGGCCTTCCCGGCTGACGGCCTGCGTGCACTGCGCTTGCGCGGGTTGAGGGCGGTGGCTCAGGCTCCTGGAAAGGACCG TCCACCCCTCCGCGCTGGCGGTGTGGACGCGGAACTCAGCGGAGAAACGCGATTGAGAGCAGTGTGTGGATTACACTATCACTGGAAAAA TACGAATTGAGAAGAAGGAAAAGACTGGAAGATGCAGACCTTGGTTCCTGTTAGTGGAAACACTGTAAGGTCCCAGAAATGGAAAAGAAA ATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAG CCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAG ACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGT GGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTAT GGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTG ACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCG GTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTCCTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTG GAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCTGAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGAC GCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATGAAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATAT GCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTCAAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGG GTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATGATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCG AGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCTACTAGAGTAGCAGGTGGTGTTGGAATTACCTGTTGGATTTTAGTCTGT AACAAAGTTGTCGCTATTGTGCTTCATCCGTTCAGCTGAACAGGAGGATGGATACAGCCGCGAGGCTAAAAAACGGATTTCCTCTTCCTA GCTTAAAATCTGATTTACACTGTTTTGTTTTTTAAGAAACAAAAGTGCATAGTTTAGATTTTTTTTTTGTTGAATATGTTTGTTCTTGGA >In-frame_PRMT2_ENST00000355680_chr21_48069651_+_WRB_ENST00000380708_chr21_40762624_+_2789nt ACTTATCCAGAAGAAAGGCAGAGGGCGCACACTGCGCAGCGCGGATGGGAAAGTTAACTGAATTATTTGCGGGAAGACAGAGGAGGTGGG GGGTCCCCCAAGCCCCAGCCATTTTGTGGCTCGTAGGGGTTGTCGCTTCCCAAGCCGTGAATGGCCCAAACCCGCCCCCCGCCCCAGGTC GGACTCCTGCCCCGCGCCCCTCTGGGTCGGACCCCAAGCCGAGCCCCCCAACCCCGCGGCTGGGCTGGGCGATTGGGGACGAGCTCCACA CATGGAGAACCTGGCCTCGCCTCGCAAGACCGCGGGACGCGCAGATGTGAAGTGCGCCTGCGCGGGGCGCAGCCCCAGCTGCAGACGATC TGTGAGCGACGCGCCGGCGCAAGTCGAGGGCGGTGGCTTGGCTTCCCTGGAATGGGGGACGTCTTAGGACTGCGCCTGCGCGGGGCGCCG GGCCCTGGGCGGGGCCTTCCCGGCTGACGGCCTGCGTGCACTGCGCTTGCGCGGGTTGAGGGCGGTGGCTCAGGCTCCTGGAAAGGACCG TCCACCCCTCCGCGCTGGCGGTGTGGACGCGGAACTCAGCGGAGAAACGCGATTGAGAGCAGTGTGTGGATTACACTATCACTGGAAAAA TACGAATTGAGAAGAAGGAAAAGACTGGAAGATGCAGACCTTGGTTCCTGTTAGTGGAAACACTGTAAGGTCCCAGAAATGGAAAAGAAA ATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAG CCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAG ACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGT GGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTAT GGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTG ACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCG GTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTCCTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTG GAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCTGAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGAC GCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATGAAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATAT GCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTCAAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGG GTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATGATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCG AGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCTACTAGAGTAGCAGGTGGTGTTGGAATTACCTGTTGGATTTTAGTCTGT AACAAAGTTGTCGCTATTGTGCTTCATCCGTTCAGCTGAACAGGAGGATGGATACAGCCGCGAGGCTAAAAAACGGATTTCCTCTTCCTA GCTTAAAATCTGATTTACACTGTTTTGTTTTTTAAGAAACAAAAGTGCATAGTTTAGATTTTTTTTTTGTTGAATATGTTTGTTCTTGGA CTTTATGAGAGAGTCTTATAAGAATCACGATTTTCTACACCTGTCATTGAGCCAAGAAAGTCCAGTTTATGACACGTATGTACTAGTGAA CACCGTCCTCGATCTGTACGAAATGTGAAATGTTTAGGGACATCTCCATGCTGTCACTTGTGATTTGCCCTCTTATGTATTTTGGTCATA TTGCCAACTGGAAAGTCAAAATTTTCTAACAACTTTAAGTAAGTTCTTTGAAGACTTAGTGCTGTTTTTAATCCAGTTTAGAAAGTAACT TAATTTTAATACCACTACTAAAAATTCGAAAATTTCTTCTTTAATCACATTCAATATGGTTAAAAGAACAACACTAATTGACATTGCGTG GGCTTTTTCTCCCTTTGTTTAAAATGTCATTTGTTGAGCAAGAGTTGTATAGTATTATCTACTTACTTGAGGCTGTTAATTTTTCATTAC AGTGTTTTGTAAATGTATCCACGAGACCATGATGCATTGTTTTGTGCTCAACTTGTGTTTTGTATTTAAAGCATTTTGAATGAAGTGTAT TTTATAAGCATTTAATATTTATGCTCTTTAGAATGGAACACAGAAAACAAACCTTATAAGTCCTGATTAATCTGAACCAATAACCTGTGT GGCCTACAAAGTATAATTCTATTAAATGTTCCTTAAAACACTTTTTTCTAATTAAAATCTTTGCAAATGCTTGTGTAACTTCCTGCCTTA >In-frame_PRMT2_ENST00000397638_chr21_48069651_+_WRB_ENST00000333781_chr21_40762624_+_2232nt CGGGCCCTGGGCGGGGCCTTCCCGGCTGACGGCCTGCGTGCACTGCGCTTGCGCGGGTTGAGGGCGGTGGCTCAGGCTCCTGGAAAGGAC CGTCCACCCCTCCGCGCTGGCGGTGTGGACGCGGAACTCAGCGGAGAAACGCGATTGAGAAATGGAAAAGAAAATGAAATAAATCAGCAG TTATGAGGCAGAGCCTAAGAGAACTATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGA GGCCGGTCTCCTGCAGGAGGGAGTACAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTT GAGAGGAGAAAAAATTCTTATCCTGAGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAA CCATGTGGGGAAGCACGTGGATGAGTACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCA CTTGGAGATGTTGGCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCT GGACGTGGGCTGTGGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGAT GGCACAGCACACGGGGCAGCTGGTCCTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCC CGAGAAGGTGGACGTGCTGGTGTCTGAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACA GATGAGAGCGGAGATCCAGGACATGAAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAA GATCAACAAGATGACGGATAAGCTCAAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTT CTACGTATTGCAGGCTGCCCTGATGATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCC TCTAGACCGCCTGGTAGCCTTTCCTACTAGAGTAGCAGGTGGTGTTGGAATTACCTGTTGGATTTTAGTCTGTAACAAAGTTGTCGCTAT TGTGCTTCATCCGTTCAGCTGAACAGGAGGATGGATACAGCCGCGAGGCTAAAAAACGGATTTCCTCTTCCTAGCTTAAAATCTGATTTA CACTGTTTTGTTTTTTAAGAAACAAAAGTGCATAGTTTAGATTTTTTTTTTGTTGAATATGTTTGTTCTTGGACTTTATGAGAGAGTCTT ATAAGAATCACGATTTTCTACACCTGTCATTGAGCCAAGAAAGTCCAGTTTATGACACGTATGTACTAGTGAACACCGTCCTCGATCTGT ACGAAATGTGAAATGTTTAGGGACATCTCCATGCTGTCACTTGTGATTTGCCCTCTTATGTATTTTGGTCATATTGCCAACTGGAAAGTC AAAATTTTCTAACAACTTTAAGTAAGTTCTTTGAAGACTTAGTGCTGTTTTTAATCCAGTTTAGAAAGTAACTTAATTTTAATACCACTA CTAAAAATTCGAAAATTTCTTCTTTAATCACATTCAATATGGTTAAAAGAACAACACTAATTGACATTGCGTGGGCTTTTTCTCCCTTTG TTTAAAATGTCATTTGTTGAGCAAGAGTTGTATAGTATTATCTACTTACTTGAGGCTGTTAATTTTTCATTACAGTGTTTTGTAAATGTA TCCACGAGACCATGATGCATTGTTTTGTGCTCAACTTGTGTTTTGTATTTAAAGCATTTTGAATGAAGTGTATTTTATAAGCATTTAATA TTTATGCTCTTTAGAATGGAACACAGAAAACAAACCTTATAAGTCCTGATTAATCTGAACCAATAACCTGTGTGGCCTACAAAGTATAAT TCTATTAAATGTTCCTTAAAACACTTTTTTCTAATTAAAATCTTTGCAAATGCTTGTGTAACTTCCTGCCTTACAGCTACTTGTTTGCTG >In-frame_PRMT2_ENST00000397638_chr21_48069651_+_WRB_ENST00000541890_chr21_40762624_+_2118nt CGGGCCCTGGGCGGGGCCTTCCCGGCTGACGGCCTGCGTGCACTGCGCTTGCGCGGGTTGAGGGCGGTGGCTCAGGCTCCTGGAAAGGAC CGTCCACCCCTCCGCGCTGGCGGTGTGGACGCGGAACTCAGCGGAGAAACGCGATTGAGAAATGGAAAAGAAAATGAAATAAATCAGCAG TTATGAGGCAGAGCCTAAGAGAACTATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGA GGCCGGTCTCCTGCAGGAGGGAGTACAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTT GAGAGGAGAAAAAATTCTTATCCTGAGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAA CCATGTGGGGAAGCACGTGGATGAGTACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCA CTTGGAGATGTTGGCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCT GGACGTGGGCTGTGGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGAT GGCACAGCACACGGGGCAGCTGGTCCTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCC CGAGAAGGTGGACGTGCTGGTGTCTGAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACA GATGAGAGCGGAGATCCAGGACATGAAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAA GATCAACAAGATGACGGATAAGCTCAAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTT CTACGTATTGCAGGCTGCCCTGATGATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCC TCTAGACCGCCTGGTAGCCTTTCCTACTAGAGTAGCAGTATTCTCCAGCAGTATTTGGACTTCCAAATGTTTCTCTTCCCCTGATAAATC TATATTAGAAAAATAGGCAATTTAGTGCTGTTTAAAATGAATGGATCTCTATTTCAAGATGGCATGTCTAGTACACTTACGTGCACCGCC TCACAAGCACACTGAAATGACAGAAAAGGACACTATGAATTAGGACAATGGACTGAAAAATAAGCAGAAAATTTAAACACACCAGTGACC ACAGTGCAACTGCAACTGACGATCAGTTTCCACCAAACTGCAACAGAGAGAGTGGCTTTGCCGTCTGGGCCAGCTGAGGACTCTCCTTGG AACCCAAAGAAGCAGTTTGTTTCCACCTACTCCCAAGAGCTGAAGATTATAAGCCAGAAGCAAACAAAGGCAGGCAAGGAAATTTGAGGT TGTTGCATCTGGAAGTAAACATGTAGCTACTTCTTCTAATAAAACAGAGTTCTATCTTTTGATTTGGTCTGGACACCTGGAGGTCAGCAA CCGAGAGCAGGAAGGAGGCACAGCAACAACAGAACAACAACAAGAGGCTGCGACAGGGGCGGCGTGGGTCAAAAGGAAGCAACCTGGAGG ACGGTCCTCCTTGCGGCTTGGAGCAGAGCTTCAGGTTGGGCACCACGACAGAGCTGGGCCAGAAGTCTAACACAGCCTGTTTGGAACACA ACCCGGGATACTTGTGTGGTTGGGTTCAGTCAGTCAAGGGAAACAAGAAGCTAACCCGTGGCTGGGAGTGTTCATGCAATGCTCGTGGAA TACTCAGCGCAAAGCCTGCCCGCAAGCACAAAGGGTATCAAGGAAGAGTTAAATGGGAAGTTGGGTCATGGTGTGGAATCATATTAAGGT >In-frame_PRMT2_ENST00000397638_chr21_48069651_+_WRB_ENST00000398753_chr21_40762624_+_1459nt CGGGCCCTGGGCGGGGCCTTCCCGGCTGACGGCCTGCGTGCACTGCGCTTGCGCGGGTTGAGGGCGGTGGCTCAGGCTCCTGGAAAGGAC CGTCCACCCCTCCGCGCTGGCGGTGTGGACGCGGAACTCAGCGGAGAAACGCGATTGAGAAATGGAAAAGAAAATGAAATAAATCAGCAG TTATGAGGCAGAGCCTAAGAGAACTATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGA GGCCGGTCTCCTGCAGGAGGGAGTACAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTT GAGAGGAGAAAAAATTCTTATCCTGAGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAA CCATGTGGGGAAGCACGTGGATGAGTACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCA CTTGGAGATGTTGGCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCT GGACGTGGGCTGTGGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGAT GGCACAGCACACGGGGCAGCTGGTCCTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCC CGAGAAGGTGGACGTGCTGGTGTCTGAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACA GATGAGAGCGGAGATCCAGGACATGAAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAA GATCAACAAGATGACGGATAAGCTCAAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTT CTACGTATTGCAGGCTGCCCTGATGATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCC TCTAGACCGCCTGGTAGCCTTTCCTACTAGAGTAGCAGGTGGTGTTGGAATTACCTGTTGGATTTTAGTCTGTAACAAAGTTGTCGCTAT TGTGCTTCATCCGTTCAGCTGAACAGGAGGATGGATACAGCCGCGAGGCTAAAAAACGGATTTCCTCTTCCTAGCTTAAAATCTGATTTA CACTGTTTTGTTTTTTAAGAAACAAAAGTGCATAGTTTAGATTTTTTTTTTGTTGAATATGTTTGTTCTTGGACTTTATGAGAGAGTCTT >In-frame_PRMT2_ENST00000397638_chr21_48069651_+_WRB_ENST00000380708_chr21_40762624_+_2232nt CGGGCCCTGGGCGGGGCCTTCCCGGCTGACGGCCTGCGTGCACTGCGCTTGCGCGGGTTGAGGGCGGTGGCTCAGGCTCCTGGAAAGGAC CGTCCACCCCTCCGCGCTGGCGGTGTGGACGCGGAACTCAGCGGAGAAACGCGATTGAGAAATGGAAAAGAAAATGAAATAAATCAGCAG TTATGAGGCAGAGCCTAAGAGAACTATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGA GGCCGGTCTCCTGCAGGAGGGAGTACAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTT GAGAGGAGAAAAAATTCTTATCCTGAGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAA CCATGTGGGGAAGCACGTGGATGAGTACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCA CTTGGAGATGTTGGCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCT GGACGTGGGCTGTGGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGAT GGCACAGCACACGGGGCAGCTGGTCCTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCC CGAGAAGGTGGACGTGCTGGTGTCTGAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACA GATGAGAGCGGAGATCCAGGACATGAAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAA GATCAACAAGATGACGGATAAGCTCAAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTT CTACGTATTGCAGGCTGCCCTGATGATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCC TCTAGACCGCCTGGTAGCCTTTCCTACTAGAGTAGCAGGTGGTGTTGGAATTACCTGTTGGATTTTAGTCTGTAACAAAGTTGTCGCTAT TGTGCTTCATCCGTTCAGCTGAACAGGAGGATGGATACAGCCGCGAGGCTAAAAAACGGATTTCCTCTTCCTAGCTTAAAATCTGATTTA CACTGTTTTGTTTTTTAAGAAACAAAAGTGCATAGTTTAGATTTTTTTTTTGTTGAATATGTTTGTTCTTGGACTTTATGAGAGAGTCTT ATAAGAATCACGATTTTCTACACCTGTCATTGAGCCAAGAAAGTCCAGTTTATGACACGTATGTACTAGTGAACACCGTCCTCGATCTGT ACGAAATGTGAAATGTTTAGGGACATCTCCATGCTGTCACTTGTGATTTGCCCTCTTATGTATTTTGGTCATATTGCCAACTGGAAAGTC AAAATTTTCTAACAACTTTAAGTAAGTTCTTTGAAGACTTAGTGCTGTTTTTAATCCAGTTTAGAAAGTAACTTAATTTTAATACCACTA CTAAAAATTCGAAAATTTCTTCTTTAATCACATTCAATATGGTTAAAAGAACAACACTAATTGACATTGCGTGGGCTTTTTCTCCCTTTG TTTAAAATGTCATTTGTTGAGCAAGAGTTGTATAGTATTATCTACTTACTTGAGGCTGTTAATTTTTCATTACAGTGTTTTGTAAATGTA TCCACGAGACCATGATGCATTGTTTTGTGCTCAACTTGTGTTTTGTATTTAAAGCATTTTGAATGAAGTGTATTTTATAAGCATTTAATA TTTATGCTCTTTAGAATGGAACACAGAAAACAAACCTTATAAGTCCTGATTAATCTGAACCAATAACCTGTGTGGCCTACAAAGTATAAT TCTATTAAATGTTCCTTAAAACACTTTTTTCTAATTAAAATCTTTGCAAATGCTTGTGTAACTTCCTGCCTTACAGCTACTTGTTTGCTG >In-frame_PRMT2_ENST00000291705_chr21_48069651_+_WRB_ENST00000333781_chr21_40762624_+_2202nt GGCCTGCGTGCACTGCGCTTGCGCGGGTTGAGGGCGGTGGCTCAGGCTCCTGGAAAGGACCGTCCACCCCTCCGCGCTGGCGGTGTGGAC GCGGAACTCAGCGGAGAAACGCGATTGAGAAATGGAAAAGAAAATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGC AACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCC AGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACA AACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGA CCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAAC AACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAG TCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTCCTGCA GAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCTGAGTG GATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATGAAGCA GGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTCAAAAC CCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATGATCTC ACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCTACTAG AGTAGCAGGTGGTGTTGGAATTACCTGTTGGATTTTAGTCTGTAACAAAGTTGTCGCTATTGTGCTTCATCCGTTCAGCTGAACAGGAGG ATGGATACAGCCGCGAGGCTAAAAAACGGATTTCCTCTTCCTAGCTTAAAATCTGATTTACACTGTTTTGTTTTTTAAGAAACAAAAGTG CATAGTTTAGATTTTTTTTTTGTTGAATATGTTTGTTCTTGGACTTTATGAGAGAGTCTTATAAGAATCACGATTTTCTACACCTGTCAT TGAGCCAAGAAAGTCCAGTTTATGACACGTATGTACTAGTGAACACCGTCCTCGATCTGTACGAAATGTGAAATGTTTAGGGACATCTCC ATGCTGTCACTTGTGATTTGCCCTCTTATGTATTTTGGTCATATTGCCAACTGGAAAGTCAAAATTTTCTAACAACTTTAAGTAAGTTCT TTGAAGACTTAGTGCTGTTTTTAATCCAGTTTAGAAAGTAACTTAATTTTAATACCACTACTAAAAATTCGAAAATTTCTTCTTTAATCA CATTCAATATGGTTAAAAGAACAACACTAATTGACATTGCGTGGGCTTTTTCTCCCTTTGTTTAAAATGTCATTTGTTGAGCAAGAGTTG TATAGTATTATCTACTTACTTGAGGCTGTTAATTTTTCATTACAGTGTTTTGTAAATGTATCCACGAGACCATGATGCATTGTTTTGTGC TCAACTTGTGTTTTGTATTTAAAGCATTTTGAATGAAGTGTATTTTATAAGCATTTAATATTTATGCTCTTTAGAATGGAACACAGAAAA CAAACCTTATAAGTCCTGATTAATCTGAACCAATAACCTGTGTGGCCTACAAAGTATAATTCTATTAAATGTTCCTTAAAACACTTTTTT CTAATTAAAATCTTTGCAAATGCTTGTGTAACTTCCTGCCTTACAGCTACTTGTTTGCTGTGAGCCACCCGCAACTGACAAGTGGCTGTT >In-frame_PRMT2_ENST00000291705_chr21_48069651_+_WRB_ENST00000541890_chr21_40762624_+_2088nt GGCCTGCGTGCACTGCGCTTGCGCGGGTTGAGGGCGGTGGCTCAGGCTCCTGGAAAGGACCGTCCACCCCTCCGCGCTGGCGGTGTGGAC GCGGAACTCAGCGGAGAAACGCGATTGAGAAATGGAAAAGAAAATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGC AACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCC AGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACA AACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGA CCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAAC AACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAG TCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTCCTGCA GAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCTGAGTG GATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATGAAGCA GGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTCAAAAC CCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATGATCTC ACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCTACTAG AGTAGCAGTATTCTCCAGCAGTATTTGGACTTCCAAATGTTTCTCTTCCCCTGATAAATCTATATTAGAAAAATAGGCAATTTAGTGCTG TTTAAAATGAATGGATCTCTATTTCAAGATGGCATGTCTAGTACACTTACGTGCACCGCCTCACAAGCACACTGAAATGACAGAAAAGGA CACTATGAATTAGGACAATGGACTGAAAAATAAGCAGAAAATTTAAACACACCAGTGACCACAGTGCAACTGCAACTGACGATCAGTTTC CACCAAACTGCAACAGAGAGAGTGGCTTTGCCGTCTGGGCCAGCTGAGGACTCTCCTTGGAACCCAAAGAAGCAGTTTGTTTCCACCTAC TCCCAAGAGCTGAAGATTATAAGCCAGAAGCAAACAAAGGCAGGCAAGGAAATTTGAGGTTGTTGCATCTGGAAGTAAACATGTAGCTAC TTCTTCTAATAAAACAGAGTTCTATCTTTTGATTTGGTCTGGACACCTGGAGGTCAGCAACCGAGAGCAGGAAGGAGGCACAGCAACAAC AGAACAACAACAAGAGGCTGCGACAGGGGCGGCGTGGGTCAAAAGGAAGCAACCTGGAGGACGGTCCTCCTTGCGGCTTGGAGCAGAGCT TCAGGTTGGGCACCACGACAGAGCTGGGCCAGAAGTCTAACACAGCCTGTTTGGAACACAACCCGGGATACTTGTGTGGTTGGGTTCAGT CAGTCAAGGGAAACAAGAAGCTAACCCGTGGCTGGGAGTGTTCATGCAATGCTCGTGGAATACTCAGCGCAAAGCCTGCCCGCAAGCACA AAGGGTATCAAGGAAGAGTTAAATGGGAAGTTGGGTCATGGTGTGGAATCATATTAAGGTCAGCATTGATGGCTTCCGGAACTTAGATAG >In-frame_PRMT2_ENST00000291705_chr21_48069651_+_WRB_ENST00000398753_chr21_40762624_+_1429nt GGCCTGCGTGCACTGCGCTTGCGCGGGTTGAGGGCGGTGGCTCAGGCTCCTGGAAAGGACCGTCCACCCCTCCGCGCTGGCGGTGTGGAC GCGGAACTCAGCGGAGAAACGCGATTGAGAAATGGAAAAGAAAATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGC AACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCC AGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACA AACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGA CCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAAC AACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAG TCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTCCTGCA GAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCTGAGTG GATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATGAAGCA GGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTCAAAAC CCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATGATCTC ACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCTACTAG AGTAGCAGGTGGTGTTGGAATTACCTGTTGGATTTTAGTCTGTAACAAAGTTGTCGCTATTGTGCTTCATCCGTTCAGCTGAACAGGAGG ATGGATACAGCCGCGAGGCTAAAAAACGGATTTCCTCTTCCTAGCTTAAAATCTGATTTACACTGTTTTGTTTTTTAAGAAACAAAAGTG >In-frame_PRMT2_ENST00000291705_chr21_48069651_+_WRB_ENST00000380708_chr21_40762624_+_2202nt GGCCTGCGTGCACTGCGCTTGCGCGGGTTGAGGGCGGTGGCTCAGGCTCCTGGAAAGGACCGTCCACCCCTCCGCGCTGGCGGTGTGGAC GCGGAACTCAGCGGAGAAACGCGATTGAGAAATGGAAAAGAAAATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGC AACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCC AGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACA AACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGA CCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAAC AACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAG TCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTCCTGCA GAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCTGAGTG GATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATGAAGCA GGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTCAAAAC CCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATGATCTC ACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCTACTAG AGTAGCAGGTGGTGTTGGAATTACCTGTTGGATTTTAGTCTGTAACAAAGTTGTCGCTATTGTGCTTCATCCGTTCAGCTGAACAGGAGG ATGGATACAGCCGCGAGGCTAAAAAACGGATTTCCTCTTCCTAGCTTAAAATCTGATTTACACTGTTTTGTTTTTTAAGAAACAAAAGTG CATAGTTTAGATTTTTTTTTTGTTGAATATGTTTGTTCTTGGACTTTATGAGAGAGTCTTATAAGAATCACGATTTTCTACACCTGTCAT TGAGCCAAGAAAGTCCAGTTTATGACACGTATGTACTAGTGAACACCGTCCTCGATCTGTACGAAATGTGAAATGTTTAGGGACATCTCC ATGCTGTCACTTGTGATTTGCCCTCTTATGTATTTTGGTCATATTGCCAACTGGAAAGTCAAAATTTTCTAACAACTTTAAGTAAGTTCT TTGAAGACTTAGTGCTGTTTTTAATCCAGTTTAGAAAGTAACTTAATTTTAATACCACTACTAAAAATTCGAAAATTTCTTCTTTAATCA CATTCAATATGGTTAAAAGAACAACACTAATTGACATTGCGTGGGCTTTTTCTCCCTTTGTTTAAAATGTCATTTGTTGAGCAAGAGTTG TATAGTATTATCTACTTACTTGAGGCTGTTAATTTTTCATTACAGTGTTTTGTAAATGTATCCACGAGACCATGATGCATTGTTTTGTGC TCAACTTGTGTTTTGTATTTAAAGCATTTTGAATGAAGTGTATTTTATAAGCATTTAATATTTATGCTCTTTAGAATGGAACACAGAAAA CAAACCTTATAAGTCCTGATTAATCTGAACCAATAACCTGTGTGGCCTACAAAGTATAATTCTATTAAATGTTCCTTAAAACACTTTTTT CTAATTAAAATCTTTGCAAATGCTTGTGTAACTTCCTGCCTTACAGCTACTTGTTTGCTGTGAGCCACCCGCAACTGACAAGTGGCTGTT >In-frame_PRMT2_ENST00000458387_chr21_48069651_+_WRB_ENST00000333781_chr21_40762624_+_2202nt GGCCTGCGTGCACTGCGCTTGCGCGGGTTGAGGGCGGTGGCTCAGGCTCCTGGAAAGGACCGTCCACCCCTCCGCGCTGGCGGTGTGGAC GCGGAACTCAGCGGAGAAACGCGATTGAGAAATGGAAAAGAAAATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGC AACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCC AGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACA AACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGA CCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAAC AACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAG TCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTCCTGCA GAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCTGAGTG GATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATGAAGCA GGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTCAAAAC CCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATGATCTC ACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCTACTAG AGTAGCAGGTGGTGTTGGAATTACCTGTTGGATTTTAGTCTGTAACAAAGTTGTCGCTATTGTGCTTCATCCGTTCAGCTGAACAGGAGG ATGGATACAGCCGCGAGGCTAAAAAACGGATTTCCTCTTCCTAGCTTAAAATCTGATTTACACTGTTTTGTTTTTTAAGAAACAAAAGTG CATAGTTTAGATTTTTTTTTTGTTGAATATGTTTGTTCTTGGACTTTATGAGAGAGTCTTATAAGAATCACGATTTTCTACACCTGTCAT TGAGCCAAGAAAGTCCAGTTTATGACACGTATGTACTAGTGAACACCGTCCTCGATCTGTACGAAATGTGAAATGTTTAGGGACATCTCC ATGCTGTCACTTGTGATTTGCCCTCTTATGTATTTTGGTCATATTGCCAACTGGAAAGTCAAAATTTTCTAACAACTTTAAGTAAGTTCT TTGAAGACTTAGTGCTGTTTTTAATCCAGTTTAGAAAGTAACTTAATTTTAATACCACTACTAAAAATTCGAAAATTTCTTCTTTAATCA CATTCAATATGGTTAAAAGAACAACACTAATTGACATTGCGTGGGCTTTTTCTCCCTTTGTTTAAAATGTCATTTGTTGAGCAAGAGTTG TATAGTATTATCTACTTACTTGAGGCTGTTAATTTTTCATTACAGTGTTTTGTAAATGTATCCACGAGACCATGATGCATTGTTTTGTGC TCAACTTGTGTTTTGTATTTAAAGCATTTTGAATGAAGTGTATTTTATAAGCATTTAATATTTATGCTCTTTAGAATGGAACACAGAAAA CAAACCTTATAAGTCCTGATTAATCTGAACCAATAACCTGTGTGGCCTACAAAGTATAATTCTATTAAATGTTCCTTAAAACACTTTTTT CTAATTAAAATCTTTGCAAATGCTTGTGTAACTTCCTGCCTTACAGCTACTTGTTTGCTGTGAGCCACCCGCAACTGACAAGTGGCTGTT >In-frame_PRMT2_ENST00000458387_chr21_48069651_+_WRB_ENST00000541890_chr21_40762624_+_2088nt GGCCTGCGTGCACTGCGCTTGCGCGGGTTGAGGGCGGTGGCTCAGGCTCCTGGAAAGGACCGTCCACCCCTCCGCGCTGGCGGTGTGGAC GCGGAACTCAGCGGAGAAACGCGATTGAGAAATGGAAAAGAAAATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGC AACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCC AGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACA AACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGA CCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAAC AACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAG TCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTCCTGCA GAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCTGAGTG GATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATGAAGCA GGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTCAAAAC CCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATGATCTC ACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCTACTAG AGTAGCAGTATTCTCCAGCAGTATTTGGACTTCCAAATGTTTCTCTTCCCCTGATAAATCTATATTAGAAAAATAGGCAATTTAGTGCTG TTTAAAATGAATGGATCTCTATTTCAAGATGGCATGTCTAGTACACTTACGTGCACCGCCTCACAAGCACACTGAAATGACAGAAAAGGA CACTATGAATTAGGACAATGGACTGAAAAATAAGCAGAAAATTTAAACACACCAGTGACCACAGTGCAACTGCAACTGACGATCAGTTTC CACCAAACTGCAACAGAGAGAGTGGCTTTGCCGTCTGGGCCAGCTGAGGACTCTCCTTGGAACCCAAAGAAGCAGTTTGTTTCCACCTAC TCCCAAGAGCTGAAGATTATAAGCCAGAAGCAAACAAAGGCAGGCAAGGAAATTTGAGGTTGTTGCATCTGGAAGTAAACATGTAGCTAC TTCTTCTAATAAAACAGAGTTCTATCTTTTGATTTGGTCTGGACACCTGGAGGTCAGCAACCGAGAGCAGGAAGGAGGCACAGCAACAAC AGAACAACAACAAGAGGCTGCGACAGGGGCGGCGTGGGTCAAAAGGAAGCAACCTGGAGGACGGTCCTCCTTGCGGCTTGGAGCAGAGCT TCAGGTTGGGCACCACGACAGAGCTGGGCCAGAAGTCTAACACAGCCTGTTTGGAACACAACCCGGGATACTTGTGTGGTTGGGTTCAGT CAGTCAAGGGAAACAAGAAGCTAACCCGTGGCTGGGAGTGTTCATGCAATGCTCGTGGAATACTCAGCGCAAAGCCTGCCCGCAAGCACA AAGGGTATCAAGGAAGAGTTAAATGGGAAGTTGGGTCATGGTGTGGAATCATATTAAGGTCAGCATTGATGGCTTCCGGAACTTAGATAG >In-frame_PRMT2_ENST00000458387_chr21_48069651_+_WRB_ENST00000398753_chr21_40762624_+_1429nt GGCCTGCGTGCACTGCGCTTGCGCGGGTTGAGGGCGGTGGCTCAGGCTCCTGGAAAGGACCGTCCACCCCTCCGCGCTGGCGGTGTGGAC GCGGAACTCAGCGGAGAAACGCGATTGAGAAATGGAAAAGAAAATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGC AACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCC AGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACA AACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGA CCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAAC AACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAG TCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTCCTGCA GAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCTGAGTG GATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATGAAGCA GGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTCAAAAC CCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATGATCTC ACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCTACTAG AGTAGCAGGTGGTGTTGGAATTACCTGTTGGATTTTAGTCTGTAACAAAGTTGTCGCTATTGTGCTTCATCCGTTCAGCTGAACAGGAGG ATGGATACAGCCGCGAGGCTAAAAAACGGATTTCCTCTTCCTAGCTTAAAATCTGATTTACACTGTTTTGTTTTTTAAGAAACAAAAGTG >In-frame_PRMT2_ENST00000458387_chr21_48069651_+_WRB_ENST00000380708_chr21_40762624_+_2202nt GGCCTGCGTGCACTGCGCTTGCGCGGGTTGAGGGCGGTGGCTCAGGCTCCTGGAAAGGACCGTCCACCCCTCCGCGCTGGCGGTGTGGAC GCGGAACTCAGCGGAGAAACGCGATTGAGAAATGGAAAAGAAAATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGC AACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCC AGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACA AACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGA CCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAAC AACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAG TCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTCCTGCA GAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCTGAGTG GATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATGAAGCA GGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTCAAAAC CCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATGATCTC ACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCTACTAG AGTAGCAGGTGGTGTTGGAATTACCTGTTGGATTTTAGTCTGTAACAAAGTTGTCGCTATTGTGCTTCATCCGTTCAGCTGAACAGGAGG ATGGATACAGCCGCGAGGCTAAAAAACGGATTTCCTCTTCCTAGCTTAAAATCTGATTTACACTGTTTTGTTTTTTAAGAAACAAAAGTG CATAGTTTAGATTTTTTTTTTGTTGAATATGTTTGTTCTTGGACTTTATGAGAGAGTCTTATAAGAATCACGATTTTCTACACCTGTCAT TGAGCCAAGAAAGTCCAGTTTATGACACGTATGTACTAGTGAACACCGTCCTCGATCTGTACGAAATGTGAAATGTTTAGGGACATCTCC ATGCTGTCACTTGTGATTTGCCCTCTTATGTATTTTGGTCATATTGCCAACTGGAAAGTCAAAATTTTCTAACAACTTTAAGTAAGTTCT TTGAAGACTTAGTGCTGTTTTTAATCCAGTTTAGAAAGTAACTTAATTTTAATACCACTACTAAAAATTCGAAAATTTCTTCTTTAATCA CATTCAATATGGTTAAAAGAACAACACTAATTGACATTGCGTGGGCTTTTTCTCCCTTTGTTTAAAATGTCATTTGTTGAGCAAGAGTTG TATAGTATTATCTACTTACTTGAGGCTGTTAATTTTTCATTACAGTGTTTTGTAAATGTATCCACGAGACCATGATGCATTGTTTTGTGC TCAACTTGTGTTTTGTATTTAAAGCATTTTGAATGAAGTGTATTTTATAAGCATTTAATATTTATGCTCTTTAGAATGGAACACAGAAAA CAAACCTTATAAGTCCTGATTAATCTGAACCAATAACCTGTGTGGCCTACAAAGTATAATTCTATTAAATGTTCCTTAAAACACTTTTTT CTAATTAAAATCTTTGCAAATGCTTGTGTAACTTCCTGCCTTACAGCTACTTGTTTGCTGTGAGCCACCCGCAACTGACAAGTGGCTGTT >In-frame_PRMT2_ENST00000451211_chr21_48069651_+_WRB_ENST00000333781_chr21_40762624_+_2202nt GGCCTGCGTGCACTGCGCTTGCGCGGGTTGAGGGCGGTGGCTCAGGCTCCTGGAAAGGACCGTCCACCCCTCCGCGCTGGCGGTGTGGAC GCGGAACTCAGCGGAGAAACGCGATTGAGAAATGGAAAAGAAAATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGC AACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCC AGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACA AACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGA CCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAAC AACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAG TCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTCCTGCA GAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCTGAGTG GATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATGAAGCA GGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTCAAAAC CCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATGATCTC ACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCTACTAG AGTAGCAGGTGGTGTTGGAATTACCTGTTGGATTTTAGTCTGTAACAAAGTTGTCGCTATTGTGCTTCATCCGTTCAGCTGAACAGGAGG ATGGATACAGCCGCGAGGCTAAAAAACGGATTTCCTCTTCCTAGCTTAAAATCTGATTTACACTGTTTTGTTTTTTAAGAAACAAAAGTG CATAGTTTAGATTTTTTTTTTGTTGAATATGTTTGTTCTTGGACTTTATGAGAGAGTCTTATAAGAATCACGATTTTCTACACCTGTCAT TGAGCCAAGAAAGTCCAGTTTATGACACGTATGTACTAGTGAACACCGTCCTCGATCTGTACGAAATGTGAAATGTTTAGGGACATCTCC ATGCTGTCACTTGTGATTTGCCCTCTTATGTATTTTGGTCATATTGCCAACTGGAAAGTCAAAATTTTCTAACAACTTTAAGTAAGTTCT TTGAAGACTTAGTGCTGTTTTTAATCCAGTTTAGAAAGTAACTTAATTTTAATACCACTACTAAAAATTCGAAAATTTCTTCTTTAATCA CATTCAATATGGTTAAAAGAACAACACTAATTGACATTGCGTGGGCTTTTTCTCCCTTTGTTTAAAATGTCATTTGTTGAGCAAGAGTTG TATAGTATTATCTACTTACTTGAGGCTGTTAATTTTTCATTACAGTGTTTTGTAAATGTATCCACGAGACCATGATGCATTGTTTTGTGC TCAACTTGTGTTTTGTATTTAAAGCATTTTGAATGAAGTGTATTTTATAAGCATTTAATATTTATGCTCTTTAGAATGGAACACAGAAAA CAAACCTTATAAGTCCTGATTAATCTGAACCAATAACCTGTGTGGCCTACAAAGTATAATTCTATTAAATGTTCCTTAAAACACTTTTTT CTAATTAAAATCTTTGCAAATGCTTGTGTAACTTCCTGCCTTACAGCTACTTGTTTGCTGTGAGCCACCCGCAACTGACAAGTGGCTGTT >In-frame_PRMT2_ENST00000451211_chr21_48069651_+_WRB_ENST00000541890_chr21_40762624_+_2088nt GGCCTGCGTGCACTGCGCTTGCGCGGGTTGAGGGCGGTGGCTCAGGCTCCTGGAAAGGACCGTCCACCCCTCCGCGCTGGCGGTGTGGAC GCGGAACTCAGCGGAGAAACGCGATTGAGAAATGGAAAAGAAAATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGC AACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCC AGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACA AACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGA CCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAAC AACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAG TCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTCCTGCA GAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCTGAGTG GATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATGAAGCA GGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTCAAAAC CCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATGATCTC ACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCTACTAG AGTAGCAGTATTCTCCAGCAGTATTTGGACTTCCAAATGTTTCTCTTCCCCTGATAAATCTATATTAGAAAAATAGGCAATTTAGTGCTG TTTAAAATGAATGGATCTCTATTTCAAGATGGCATGTCTAGTACACTTACGTGCACCGCCTCACAAGCACACTGAAATGACAGAAAAGGA CACTATGAATTAGGACAATGGACTGAAAAATAAGCAGAAAATTTAAACACACCAGTGACCACAGTGCAACTGCAACTGACGATCAGTTTC CACCAAACTGCAACAGAGAGAGTGGCTTTGCCGTCTGGGCCAGCTGAGGACTCTCCTTGGAACCCAAAGAAGCAGTTTGTTTCCACCTAC TCCCAAGAGCTGAAGATTATAAGCCAGAAGCAAACAAAGGCAGGCAAGGAAATTTGAGGTTGTTGCATCTGGAAGTAAACATGTAGCTAC TTCTTCTAATAAAACAGAGTTCTATCTTTTGATTTGGTCTGGACACCTGGAGGTCAGCAACCGAGAGCAGGAAGGAGGCACAGCAACAAC AGAACAACAACAAGAGGCTGCGACAGGGGCGGCGTGGGTCAAAAGGAAGCAACCTGGAGGACGGTCCTCCTTGCGGCTTGGAGCAGAGCT TCAGGTTGGGCACCACGACAGAGCTGGGCCAGAAGTCTAACACAGCCTGTTTGGAACACAACCCGGGATACTTGTGTGGTTGGGTTCAGT CAGTCAAGGGAAACAAGAAGCTAACCCGTGGCTGGGAGTGTTCATGCAATGCTCGTGGAATACTCAGCGCAAAGCCTGCCCGCAAGCACA AAGGGTATCAAGGAAGAGTTAAATGGGAAGTTGGGTCATGGTGTGGAATCATATTAAGGTCAGCATTGATGGCTTCCGGAACTTAGATAG >In-frame_PRMT2_ENST00000451211_chr21_48069651_+_WRB_ENST00000398753_chr21_40762624_+_1429nt GGCCTGCGTGCACTGCGCTTGCGCGGGTTGAGGGCGGTGGCTCAGGCTCCTGGAAAGGACCGTCCACCCCTCCGCGCTGGCGGTGTGGAC GCGGAACTCAGCGGAGAAACGCGATTGAGAAATGGAAAAGAAAATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGC AACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCC AGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACA AACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGA CCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAAC AACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAG TCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTCCTGCA GAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCTGAGTG GATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATGAAGCA GGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTCAAAAC CCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATGATCTC ACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCTACTAG AGTAGCAGGTGGTGTTGGAATTACCTGTTGGATTTTAGTCTGTAACAAAGTTGTCGCTATTGTGCTTCATCCGTTCAGCTGAACAGGAGG ATGGATACAGCCGCGAGGCTAAAAAACGGATTTCCTCTTCCTAGCTTAAAATCTGATTTACACTGTTTTGTTTTTTAAGAAACAAAAGTG >In-frame_PRMT2_ENST00000451211_chr21_48069651_+_WRB_ENST00000380708_chr21_40762624_+_2202nt GGCCTGCGTGCACTGCGCTTGCGCGGGTTGAGGGCGGTGGCTCAGGCTCCTGGAAAGGACCGTCCACCCCTCCGCGCTGGCGGTGTGGAC GCGGAACTCAGCGGAGAAACGCGATTGAGAAATGGAAAAGAAAATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGC AACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCC AGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACA AACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGA CCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAAC AACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAG TCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTCCTGCA GAACGGCTTTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCTGAGTG GATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATGAAGCA GGAGCTCTCCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTCAAAAC CCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATGATCTC ACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCTACTAG AGTAGCAGGTGGTGTTGGAATTACCTGTTGGATTTTAGTCTGTAACAAAGTTGTCGCTATTGTGCTTCATCCGTTCAGCTGAACAGGAGG ATGGATACAGCCGCGAGGCTAAAAAACGGATTTCCTCTTCCTAGCTTAAAATCTGATTTACACTGTTTTGTTTTTTAAGAAACAAAAGTG CATAGTTTAGATTTTTTTTTTGTTGAATATGTTTGTTCTTGGACTTTATGAGAGAGTCTTATAAGAATCACGATTTTCTACACCTGTCAT TGAGCCAAGAAAGTCCAGTTTATGACACGTATGTACTAGTGAACACCGTCCTCGATCTGTACGAAATGTGAAATGTTTAGGGACATCTCC ATGCTGTCACTTGTGATTTGCCCTCTTATGTATTTTGGTCATATTGCCAACTGGAAAGTCAAAATTTTCTAACAACTTTAAGTAAGTTCT TTGAAGACTTAGTGCTGTTTTTAATCCAGTTTAGAAAGTAACTTAATTTTAATACCACTACTAAAAATTCGAAAATTTCTTCTTTAATCA CATTCAATATGGTTAAAAGAACAACACTAATTGACATTGCGTGGGCTTTTTCTCCCTTTGTTTAAAATGTCATTTGTTGAGCAAGAGTTG TATAGTATTATCTACTTACTTGAGGCTGTTAATTTTTCATTACAGTGTTTTGTAAATGTATCCACGAGACCATGATGCATTGTTTTGTGC TCAACTTGTGTTTTGTATTTAAAGCATTTTGAATGAAGTGTATTTTATAAGCATTTAATATTTATGCTCTTTAGAATGGAACACAGAAAA CAAACCTTATAAGTCCTGATTAATCTGAACCAATAACCTGTGTGGCCTACAAAGTATAATTCTATTAAATGTTCCTTAAAACACTTTTTT CTAATTAAAATCTTTGCAAATGCTTGTGTAACTTCCTGCCTTACAGCTACTTGTTTGCTGTGAGCCACCCGCAACTGACAAGTGGCTGTT >In-frame_PRMT2_ENST00000397637_chr21_48069651_+_WRB_ENST00000333781_chr21_40762624_+_2981nt GCGTGCACTGCGCTTGCGCGGGTTGAGGGCGGTGGCTCAGGCTCCTGGAAAGGACCGTCCACCCCTCCGCGCTGGCGGTGTGGACGCGGA ACTCAGCGGAGAAACGCGATTGAGGTAGGTGTCCTGATGGGCAGCTCAGATGGCTGGACTGCACGTAAGGAAGGACAGGCCAGGTGAGGC GTCCTCGCACTGCGTGTGCGTCGCTGGCGGACAGAGGCCTCCGCCCCCTTTTGGGACCTCCGAGCGCCTTCGCGATCTCAGCCACTTTCC CTGGCGTCCAAACGGGAGCTCGGTCCCCGTCACACCCTTCCCTGCGTGCCGCACCCCTTCCCGGCCACTCCCGCCGTCCAGCGCCTTCTA CGGCCACGCCCACCCCACCACCATCTCTGTCACGCCCTTCGCGGCCACGCCCACCTGCCTGGCGGCCCCTGCCCCGAAGCTCGCGGCGCT GTCCCAGCCTGACCCTCTCGTGCCCCTGCGTCCACGCGTGGCCCTCTCGCTTCCTGCCCCCTTCTCACCCCCCTTCACTGGCCACCTGTT CCAACCCTCCATGATCCTGTTCCTCCCGAGGGCATCTTAGGAGGGCAGGGTCCTGCGCGCACTGCGGCCTCCACTCCGACCCCGTCCCAG TTTGGACCCAGGTCTTCCAATGAAAATATAATTATGCAAATCAGTAAGCATTTGTAACTACGAATATCACAAAAATAAGCTTCAAGTCTG GATTTAGAAGTGAAGCATGCATTTTAAACAAAGAATTGCTATGCAATTTTAAAAACACATTGATCCCAGAGCAGTGTGTGGATTACACTA TCACTGGAAAAATACGAATTGAGAAGAAGGAAAAGACTGGAAGATGCAGACCTTGGTTCCTGTTAGTGGAAACACTGTAAGGTCCCAGAA ATGGAAAAGAAAATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCG CAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCT GCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGT GCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGACCCCGAGGACACGTGGCAGGATGAAGAGTAC TTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGAAT AAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGA GCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTCCTGCAGAACGGCTTTGCTGACATCATCACCGTGTAC CAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCTGAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTG CTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATGAAGCAGGAGCTCTCCACAGTCAACATGATGGACGAG TTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTCAAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCC AAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATGATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTG GCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCTACTAGAGTAGCAGGTGGTGTTGGAATTACCTGTTGG ATTTTAGTCTGTAACAAAGTTGTCGCTATTGTGCTTCATCCGTTCAGCTGAACAGGAGGATGGATACAGCCGCGAGGCTAAAAAACGGAT TTCCTCTTCCTAGCTTAAAATCTGATTTACACTGTTTTGTTTTTTAAGAAACAAAAGTGCATAGTTTAGATTTTTTTTTTGTTGAATATG TTTGTTCTTGGACTTTATGAGAGAGTCTTATAAGAATCACGATTTTCTACACCTGTCATTGAGCCAAGAAAGTCCAGTTTATGACACGTA TGTACTAGTGAACACCGTCCTCGATCTGTACGAAATGTGAAATGTTTAGGGACATCTCCATGCTGTCACTTGTGATTTGCCCTCTTATGT ATTTTGGTCATATTGCCAACTGGAAAGTCAAAATTTTCTAACAACTTTAAGTAAGTTCTTTGAAGACTTAGTGCTGTTTTTAATCCAGTT TAGAAAGTAACTTAATTTTAATACCACTACTAAAAATTCGAAAATTTCTTCTTTAATCACATTCAATATGGTTAAAAGAACAACACTAAT TGACATTGCGTGGGCTTTTTCTCCCTTTGTTTAAAATGTCATTTGTTGAGCAAGAGTTGTATAGTATTATCTACTTACTTGAGGCTGTTA ATTTTTCATTACAGTGTTTTGTAAATGTATCCACGAGACCATGATGCATTGTTTTGTGCTCAACTTGTGTTTTGTATTTAAAGCATTTTG AATGAAGTGTATTTTATAAGCATTTAATATTTATGCTCTTTAGAATGGAACACAGAAAACAAACCTTATAAGTCCTGATTAATCTGAACC AATAACCTGTGTGGCCTACAAAGTATAATTCTATTAAATGTTCCTTAAAACACTTTTTTCTAATTAAAATCTTTGCAAATGCTTGTGTAA CTTCCTGCCTTACAGCTACTTGTTTGCTGTGAGCCACCCGCAACTGACAAGTGGCTGTTAACTGAGTCACCATATCCCAGTAAAGCTGAA >In-frame_PRMT2_ENST00000397637_chr21_48069651_+_WRB_ENST00000541890_chr21_40762624_+_2867nt GCGTGCACTGCGCTTGCGCGGGTTGAGGGCGGTGGCTCAGGCTCCTGGAAAGGACCGTCCACCCCTCCGCGCTGGCGGTGTGGACGCGGA ACTCAGCGGAGAAACGCGATTGAGGTAGGTGTCCTGATGGGCAGCTCAGATGGCTGGACTGCACGTAAGGAAGGACAGGCCAGGTGAGGC GTCCTCGCACTGCGTGTGCGTCGCTGGCGGACAGAGGCCTCCGCCCCCTTTTGGGACCTCCGAGCGCCTTCGCGATCTCAGCCACTTTCC CTGGCGTCCAAACGGGAGCTCGGTCCCCGTCACACCCTTCCCTGCGTGCCGCACCCCTTCCCGGCCACTCCCGCCGTCCAGCGCCTTCTA CGGCCACGCCCACCCCACCACCATCTCTGTCACGCCCTTCGCGGCCACGCCCACCTGCCTGGCGGCCCCTGCCCCGAAGCTCGCGGCGCT GTCCCAGCCTGACCCTCTCGTGCCCCTGCGTCCACGCGTGGCCCTCTCGCTTCCTGCCCCCTTCTCACCCCCCTTCACTGGCCACCTGTT CCAACCCTCCATGATCCTGTTCCTCCCGAGGGCATCTTAGGAGGGCAGGGTCCTGCGCGCACTGCGGCCTCCACTCCGACCCCGTCCCAG TTTGGACCCAGGTCTTCCAATGAAAATATAATTATGCAAATCAGTAAGCATTTGTAACTACGAATATCACAAAAATAAGCTTCAAGTCTG GATTTAGAAGTGAAGCATGCATTTTAAACAAAGAATTGCTATGCAATTTTAAAAACACATTGATCCCAGAGCAGTGTGTGGATTACACTA TCACTGGAAAAATACGAATTGAGAAGAAGGAAAAGACTGGAAGATGCAGACCTTGGTTCCTGTTAGTGGAAACACTGTAAGGTCCCAGAA ATGGAAAAGAAAATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCG CAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCT GCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGT GCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGACCCCGAGGACACGTGGCAGGATGAAGAGTAC TTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGAAT AAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGA GCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTCCTGCAGAACGGCTTTGCTGACATCATCACCGTGTAC CAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCTGAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTG CTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATGAAGCAGGAGCTCTCCACAGTCAACATGATGGACGAG TTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTCAAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCC AAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATGATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTG GCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCTACTAGAGTAGCAGTATTCTCCAGCAGTATTTGGACT TCCAAATGTTTCTCTTCCCCTGATAAATCTATATTAGAAAAATAGGCAATTTAGTGCTGTTTAAAATGAATGGATCTCTATTTCAAGATG GCATGTCTAGTACACTTACGTGCACCGCCTCACAAGCACACTGAAATGACAGAAAAGGACACTATGAATTAGGACAATGGACTGAAAAAT AAGCAGAAAATTTAAACACACCAGTGACCACAGTGCAACTGCAACTGACGATCAGTTTCCACCAAACTGCAACAGAGAGAGTGGCTTTGC CGTCTGGGCCAGCTGAGGACTCTCCTTGGAACCCAAAGAAGCAGTTTGTTTCCACCTACTCCCAAGAGCTGAAGATTATAAGCCAGAAGC AAACAAAGGCAGGCAAGGAAATTTGAGGTTGTTGCATCTGGAAGTAAACATGTAGCTACTTCTTCTAATAAAACAGAGTTCTATCTTTTG ATTTGGTCTGGACACCTGGAGGTCAGCAACCGAGAGCAGGAAGGAGGCACAGCAACAACAGAACAACAACAAGAGGCTGCGACAGGGGCG GCGTGGGTCAAAAGGAAGCAACCTGGAGGACGGTCCTCCTTGCGGCTTGGAGCAGAGCTTCAGGTTGGGCACCACGACAGAGCTGGGCCA GAAGTCTAACACAGCCTGTTTGGAACACAACCCGGGATACTTGTGTGGTTGGGTTCAGTCAGTCAAGGGAAACAAGAAGCTAACCCGTGG CTGGGAGTGTTCATGCAATGCTCGTGGAATACTCAGCGCAAAGCCTGCCCGCAAGCACAAAGGGTATCAAGGAAGAGTTAAATGGGAAGT >In-frame_PRMT2_ENST00000397637_chr21_48069651_+_WRB_ENST00000398753_chr21_40762624_+_2208nt GCGTGCACTGCGCTTGCGCGGGTTGAGGGCGGTGGCTCAGGCTCCTGGAAAGGACCGTCCACCCCTCCGCGCTGGCGGTGTGGACGCGGA ACTCAGCGGAGAAACGCGATTGAGGTAGGTGTCCTGATGGGCAGCTCAGATGGCTGGACTGCACGTAAGGAAGGACAGGCCAGGTGAGGC GTCCTCGCACTGCGTGTGCGTCGCTGGCGGACAGAGGCCTCCGCCCCCTTTTGGGACCTCCGAGCGCCTTCGCGATCTCAGCCACTTTCC CTGGCGTCCAAACGGGAGCTCGGTCCCCGTCACACCCTTCCCTGCGTGCCGCACCCCTTCCCGGCCACTCCCGCCGTCCAGCGCCTTCTA CGGCCACGCCCACCCCACCACCATCTCTGTCACGCCCTTCGCGGCCACGCCCACCTGCCTGGCGGCCCCTGCCCCGAAGCTCGCGGCGCT GTCCCAGCCTGACCCTCTCGTGCCCCTGCGTCCACGCGTGGCCCTCTCGCTTCCTGCCCCCTTCTCACCCCCCTTCACTGGCCACCTGTT CCAACCCTCCATGATCCTGTTCCTCCCGAGGGCATCTTAGGAGGGCAGGGTCCTGCGCGCACTGCGGCCTCCACTCCGACCCCGTCCCAG TTTGGACCCAGGTCTTCCAATGAAAATATAATTATGCAAATCAGTAAGCATTTGTAACTACGAATATCACAAAAATAAGCTTCAAGTCTG GATTTAGAAGTGAAGCATGCATTTTAAACAAAGAATTGCTATGCAATTTTAAAAACACATTGATCCCAGAGCAGTGTGTGGATTACACTA TCACTGGAAAAATACGAATTGAGAAGAAGGAAAAGACTGGAAGATGCAGACCTTGGTTCCTGTTAGTGGAAACACTGTAAGGTCCCAGAA ATGGAAAAGAAAATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCG CAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCT GCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGT GCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGACCCCGAGGACACGTGGCAGGATGAAGAGTAC TTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGAAT AAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGA GCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTCCTGCAGAACGGCTTTGCTGACATCATCACCGTGTAC CAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCTGAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTG CTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATGAAGCAGGAGCTCTCCACAGTCAACATGATGGACGAG TTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTCAAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCC AAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATGATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTG GCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCTACTAGAGTAGCAGGTGGTGTTGGAATTACCTGTTGG ATTTTAGTCTGTAACAAAGTTGTCGCTATTGTGCTTCATCCGTTCAGCTGAACAGGAGGATGGATACAGCCGCGAGGCTAAAAAACGGAT TTCCTCTTCCTAGCTTAAAATCTGATTTACACTGTTTTGTTTTTTAAGAAACAAAAGTGCATAGTTTAGATTTTTTTTTTGTTGAATATG >In-frame_PRMT2_ENST00000397637_chr21_48069651_+_WRB_ENST00000380708_chr21_40762624_+_2981nt GCGTGCACTGCGCTTGCGCGGGTTGAGGGCGGTGGCTCAGGCTCCTGGAAAGGACCGTCCACCCCTCCGCGCTGGCGGTGTGGACGCGGA ACTCAGCGGAGAAACGCGATTGAGGTAGGTGTCCTGATGGGCAGCTCAGATGGCTGGACTGCACGTAAGGAAGGACAGGCCAGGTGAGGC GTCCTCGCACTGCGTGTGCGTCGCTGGCGGACAGAGGCCTCCGCCCCCTTTTGGGACCTCCGAGCGCCTTCGCGATCTCAGCCACTTTCC CTGGCGTCCAAACGGGAGCTCGGTCCCCGTCACACCCTTCCCTGCGTGCCGCACCCCTTCCCGGCCACTCCCGCCGTCCAGCGCCTTCTA CGGCCACGCCCACCCCACCACCATCTCTGTCACGCCCTTCGCGGCCACGCCCACCTGCCTGGCGGCCCCTGCCCCGAAGCTCGCGGCGCT GTCCCAGCCTGACCCTCTCGTGCCCCTGCGTCCACGCGTGGCCCTCTCGCTTCCTGCCCCCTTCTCACCCCCCTTCACTGGCCACCTGTT CCAACCCTCCATGATCCTGTTCCTCCCGAGGGCATCTTAGGAGGGCAGGGTCCTGCGCGCACTGCGGCCTCCACTCCGACCCCGTCCCAG TTTGGACCCAGGTCTTCCAATGAAAATATAATTATGCAAATCAGTAAGCATTTGTAACTACGAATATCACAAAAATAAGCTTCAAGTCTG GATTTAGAAGTGAAGCATGCATTTTAAACAAAGAATTGCTATGCAATTTTAAAAACACATTGATCCCAGAGCAGTGTGTGGATTACACTA TCACTGGAAAAATACGAATTGAGAAGAAGGAAAAGACTGGAAGATGCAGACCTTGGTTCCTGTTAGTGGAAACACTGTAAGGTCCCAGAA ATGGAAAAGAAAATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCG CAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCT GCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGT GCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGACCCCGAGGACACGTGGCAGGATGAAGAGTAC TTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGAAT AAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGA GCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTCCTGCAGAACGGCTTTGCTGACATCATCACCGTGTAC CAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCTGAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTG CTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATGAAGCAGGAGCTCTCCACAGTCAACATGATGGACGAG TTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTCAAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCC AAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATGATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTG GCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCTACTAGAGTAGCAGGTGGTGTTGGAATTACCTGTTGG ATTTTAGTCTGTAACAAAGTTGTCGCTATTGTGCTTCATCCGTTCAGCTGAACAGGAGGATGGATACAGCCGCGAGGCTAAAAAACGGAT TTCCTCTTCCTAGCTTAAAATCTGATTTACACTGTTTTGTTTTTTAAGAAACAAAAGTGCATAGTTTAGATTTTTTTTTTGTTGAATATG TTTGTTCTTGGACTTTATGAGAGAGTCTTATAAGAATCACGATTTTCTACACCTGTCATTGAGCCAAGAAAGTCCAGTTTATGACACGTA TGTACTAGTGAACACCGTCCTCGATCTGTACGAAATGTGAAATGTTTAGGGACATCTCCATGCTGTCACTTGTGATTTGCCCTCTTATGT ATTTTGGTCATATTGCCAACTGGAAAGTCAAAATTTTCTAACAACTTTAAGTAAGTTCTTTGAAGACTTAGTGCTGTTTTTAATCCAGTT TAGAAAGTAACTTAATTTTAATACCACTACTAAAAATTCGAAAATTTCTTCTTTAATCACATTCAATATGGTTAAAAGAACAACACTAAT TGACATTGCGTGGGCTTTTTCTCCCTTTGTTTAAAATGTCATTTGTTGAGCAAGAGTTGTATAGTATTATCTACTTACTTGAGGCTGTTA ATTTTTCATTACAGTGTTTTGTAAATGTATCCACGAGACCATGATGCATTGTTTTGTGCTCAACTTGTGTTTTGTATTTAAAGCATTTTG AATGAAGTGTATTTTATAAGCATTTAATATTTATGCTCTTTAGAATGGAACACAGAAAACAAACCTTATAAGTCCTGATTAATCTGAACC AATAACCTGTGTGGCCTACAAAGTATAATTCTATTAAATGTTCCTTAAAACACTTTTTTCTAATTAAAATCTTTGCAAATGCTTGTGTAA CTTCCTGCCTTACAGCTACTTGTTTGCTGTGAGCCACCCGCAACTGACAAGTGGCTGTTAACTGAGTCACCATATCCCAGTAAAGCTGAA >In-frame_PRMT2_ENST00000334494_chr21_48069651_+_WRB_ENST00000333781_chr21_40762624_+_2194nt TGCACTGCGCTTGCGCGGGTTGAGGGCGGTGGCTCAGGCTCCTGGAAAGGACCGTCCACCCCTCCGCGCTGGCGGTGTGGACGCGGAACT CAGCGGAGAAACGCGATTGAGAAATGGAAAAGAAAATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGCAACATCAG GTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCCAGAGGAGT TTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACAAACCACTG CAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGACCCCGAGG ACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAACAACTAAAT ACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAGTCTCTTCT GTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTCCTGCAGAACGGCT TTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCTGAGTGGATGGGGA CCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATGAAGCAGGAGCTCT CCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTCAAAACCCATGTGA AAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATGATCTCACTCATTT GGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCTACTAGAGTAGCAG GTGGTGTTGGAATTACCTGTTGGATTTTAGTCTGTAACAAAGTTGTCGCTATTGTGCTTCATCCGTTCAGCTGAACAGGAGGATGGATAC AGCCGCGAGGCTAAAAAACGGATTTCCTCTTCCTAGCTTAAAATCTGATTTACACTGTTTTGTTTTTTAAGAAACAAAAGTGCATAGTTT AGATTTTTTTTTTGTTGAATATGTTTGTTCTTGGACTTTATGAGAGAGTCTTATAAGAATCACGATTTTCTACACCTGTCATTGAGCCAA GAAAGTCCAGTTTATGACACGTATGTACTAGTGAACACCGTCCTCGATCTGTACGAAATGTGAAATGTTTAGGGACATCTCCATGCTGTC ACTTGTGATTTGCCCTCTTATGTATTTTGGTCATATTGCCAACTGGAAAGTCAAAATTTTCTAACAACTTTAAGTAAGTTCTTTGAAGAC TTAGTGCTGTTTTTAATCCAGTTTAGAAAGTAACTTAATTTTAATACCACTACTAAAAATTCGAAAATTTCTTCTTTAATCACATTCAAT ATGGTTAAAAGAACAACACTAATTGACATTGCGTGGGCTTTTTCTCCCTTTGTTTAAAATGTCATTTGTTGAGCAAGAGTTGTATAGTAT TATCTACTTACTTGAGGCTGTTAATTTTTCATTACAGTGTTTTGTAAATGTATCCACGAGACCATGATGCATTGTTTTGTGCTCAACTTG TGTTTTGTATTTAAAGCATTTTGAATGAAGTGTATTTTATAAGCATTTAATATTTATGCTCTTTAGAATGGAACACAGAAAACAAACCTT ATAAGTCCTGATTAATCTGAACCAATAACCTGTGTGGCCTACAAAGTATAATTCTATTAAATGTTCCTTAAAACACTTTTTTCTAATTAA AATCTTTGCAAATGCTTGTGTAACTTCCTGCCTTACAGCTACTTGTTTGCTGTGAGCCACCCGCAACTGACAAGTGGCTGTTAACTGAGT >In-frame_PRMT2_ENST00000334494_chr21_48069651_+_WRB_ENST00000541890_chr21_40762624_+_2080nt TGCACTGCGCTTGCGCGGGTTGAGGGCGGTGGCTCAGGCTCCTGGAAAGGACCGTCCACCCCTCCGCGCTGGCGGTGTGGACGCGGAACT CAGCGGAGAAACGCGATTGAGAAATGGAAAAGAAAATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGCAACATCAG GTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCCAGAGGAGT TTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACAAACCACTG CAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGACCCCGAGG ACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAACAACTAAAT ACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAGTCTCTTCT GTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTCCTGCAGAACGGCT TTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCTGAGTGGATGGGGA CCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATGAAGCAGGAGCTCT CCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTCAAAACCCATGTGA AAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATGATCTCACTCATTT GGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCTACTAGAGTAGCAG TATTCTCCAGCAGTATTTGGACTTCCAAATGTTTCTCTTCCCCTGATAAATCTATATTAGAAAAATAGGCAATTTAGTGCTGTTTAAAAT GAATGGATCTCTATTTCAAGATGGCATGTCTAGTACACTTACGTGCACCGCCTCACAAGCACACTGAAATGACAGAAAAGGACACTATGA ATTAGGACAATGGACTGAAAAATAAGCAGAAAATTTAAACACACCAGTGACCACAGTGCAACTGCAACTGACGATCAGTTTCCACCAAAC TGCAACAGAGAGAGTGGCTTTGCCGTCTGGGCCAGCTGAGGACTCTCCTTGGAACCCAAAGAAGCAGTTTGTTTCCACCTACTCCCAAGA GCTGAAGATTATAAGCCAGAAGCAAACAAAGGCAGGCAAGGAAATTTGAGGTTGTTGCATCTGGAAGTAAACATGTAGCTACTTCTTCTA ATAAAACAGAGTTCTATCTTTTGATTTGGTCTGGACACCTGGAGGTCAGCAACCGAGAGCAGGAAGGAGGCACAGCAACAACAGAACAAC AACAAGAGGCTGCGACAGGGGCGGCGTGGGTCAAAAGGAAGCAACCTGGAGGACGGTCCTCCTTGCGGCTTGGAGCAGAGCTTCAGGTTG GGCACCACGACAGAGCTGGGCCAGAAGTCTAACACAGCCTGTTTGGAACACAACCCGGGATACTTGTGTGGTTGGGTTCAGTCAGTCAAG GGAAACAAGAAGCTAACCCGTGGCTGGGAGTGTTCATGCAATGCTCGTGGAATACTCAGCGCAAAGCCTGCCCGCAAGCACAAAGGGTAT CAAGGAAGAGTTAAATGGGAAGTTGGGTCATGGTGTGGAATCATATTAAGGTCAGCATTGATGGCTTCCGGAACTTAGATAGAAAGCAGT >In-frame_PRMT2_ENST00000334494_chr21_48069651_+_WRB_ENST00000398753_chr21_40762624_+_1421nt TGCACTGCGCTTGCGCGGGTTGAGGGCGGTGGCTCAGGCTCCTGGAAAGGACCGTCCACCCCTCCGCGCTGGCGGTGTGGACGCGGAACT CAGCGGAGAAACGCGATTGAGAAATGGAAAAGAAAATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGCAACATCAG GTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCCAGAGGAGT TTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACAAACCACTG CAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGACCCCGAGG ACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAACAACTAAAT ACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAGTCTCTTCT GTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTCCTGCAGAACGGCT TTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCTGAGTGGATGGGGA CCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATGAAGCAGGAGCTCT CCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTCAAAACCCATGTGA AAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATGATCTCACTCATTT GGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCTACTAGAGTAGCAG GTGGTGTTGGAATTACCTGTTGGATTTTAGTCTGTAACAAAGTTGTCGCTATTGTGCTTCATCCGTTCAGCTGAACAGGAGGATGGATAC AGCCGCGAGGCTAAAAAACGGATTTCCTCTTCCTAGCTTAAAATCTGATTTACACTGTTTTGTTTTTTAAGAAACAAAAGTGCATAGTTT >In-frame_PRMT2_ENST00000334494_chr21_48069651_+_WRB_ENST00000380708_chr21_40762624_+_2194nt TGCACTGCGCTTGCGCGGGTTGAGGGCGGTGGCTCAGGCTCCTGGAAAGGACCGTCCACCCCTCCGCGCTGGCGGTGTGGACGCGGAACT CAGCGGAGAAACGCGATTGAGAAATGGAAAAGAAAATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGCAACATCAG GTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCCAGAGGAGT TTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACAAACCACTG CAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGACCCCGAGG ACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAACAACTAAAT ACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAGTCTCTTCT GTGCACACTATGCGCGGCCTAGAGCGGTGTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTCCTGCAGAACGGCT TTGCTGACATCATCACCGTGTACCAGCAGAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCTGAGTGGATGGGGA CCTGCCTGCTGATGTCCAGGGTGCTGCAGAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATGAAGCAGGAGCTCT CCACAGTCAACATGATGGACGAGTTTGCCAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTCAAAACCCATGTGA AAGCTCGGACAGCTCAATTAGCCAAGATAAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATGATCTCACTCATTT GGAAGTATTATTCTGTCCCTGTGGCTGTCGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCTACTAGAGTAGCAG GTGGTGTTGGAATTACCTGTTGGATTTTAGTCTGTAACAAAGTTGTCGCTATTGTGCTTCATCCGTTCAGCTGAACAGGAGGATGGATAC AGCCGCGAGGCTAAAAAACGGATTTCCTCTTCCTAGCTTAAAATCTGATTTACACTGTTTTGTTTTTTAAGAAACAAAAGTGCATAGTTT AGATTTTTTTTTTGTTGAATATGTTTGTTCTTGGACTTTATGAGAGAGTCTTATAAGAATCACGATTTTCTACACCTGTCATTGAGCCAA GAAAGTCCAGTTTATGACACGTATGTACTAGTGAACACCGTCCTCGATCTGTACGAAATGTGAAATGTTTAGGGACATCTCCATGCTGTC ACTTGTGATTTGCCCTCTTATGTATTTTGGTCATATTGCCAACTGGAAAGTCAAAATTTTCTAACAACTTTAAGTAAGTTCTTTGAAGAC TTAGTGCTGTTTTTAATCCAGTTTAGAAAGTAACTTAATTTTAATACCACTACTAAAAATTCGAAAATTTCTTCTTTAATCACATTCAAT ATGGTTAAAAGAACAACACTAATTGACATTGCGTGGGCTTTTTCTCCCTTTGTTTAAAATGTCATTTGTTGAGCAAGAGTTGTATAGTAT TATCTACTTACTTGAGGCTGTTAATTTTTCATTACAGTGTTTTGTAAATGTATCCACGAGACCATGATGCATTGTTTTGTGCTCAACTTG TGTTTTGTATTTAAAGCATTTTGAATGAAGTGTATTTTATAAGCATTTAATATTTATGCTCTTTAGAATGGAACACAGAAAACAAACCTT ATAAGTCCTGATTAATCTGAACCAATAACCTGTGTGGCCTACAAAGTATAATTCTATTAAATGTTCCTTAAAACACTTTTTTCTAATTAA AATCTTTGCAAATGCTTGTGTAACTTCCTGCCTTACAGCTACTTGTTTGCTGTGAGCCACCCGCAACTGACAAGTGGCTGTTAACTGAGT >In-frame_PRMT2_ENST00000440086_chr21_48069651_+_WRB_ENST00000333781_chr21_40762624_+_2166nt GTGGCTCAGGCTCCTGGAAAGGACCGTCCACCCCTCCGCGCTGGCGGTGTGGACGCGGAACTCAGCGGAGAAACGCGATTGAGAAATGGA AAAGAAAATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGG AGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCAC CGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGG CTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGG CAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGA ATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGT GTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTCCTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCA GAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCTGAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCA GAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATGAAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGC CAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTCAAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGAT AAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATGATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGT CGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCTACTAGAGTAGCAGGTGGTGTTGGAATTACCTGTTGGATTTT AGTCTGTAACAAAGTTGTCGCTATTGTGCTTCATCCGTTCAGCTGAACAGGAGGATGGATACAGCCGCGAGGCTAAAAAACGGATTTCCT CTTCCTAGCTTAAAATCTGATTTACACTGTTTTGTTTTTTAAGAAACAAAAGTGCATAGTTTAGATTTTTTTTTTGTTGAATATGTTTGT TCTTGGACTTTATGAGAGAGTCTTATAAGAATCACGATTTTCTACACCTGTCATTGAGCCAAGAAAGTCCAGTTTATGACACGTATGTAC TAGTGAACACCGTCCTCGATCTGTACGAAATGTGAAATGTTTAGGGACATCTCCATGCTGTCACTTGTGATTTGCCCTCTTATGTATTTT GGTCATATTGCCAACTGGAAAGTCAAAATTTTCTAACAACTTTAAGTAAGTTCTTTGAAGACTTAGTGCTGTTTTTAATCCAGTTTAGAA AGTAACTTAATTTTAATACCACTACTAAAAATTCGAAAATTTCTTCTTTAATCACATTCAATATGGTTAAAAGAACAACACTAATTGACA TTGCGTGGGCTTTTTCTCCCTTTGTTTAAAATGTCATTTGTTGAGCAAGAGTTGTATAGTATTATCTACTTACTTGAGGCTGTTAATTTT TCATTACAGTGTTTTGTAAATGTATCCACGAGACCATGATGCATTGTTTTGTGCTCAACTTGTGTTTTGTATTTAAAGCATTTTGAATGA AGTGTATTTTATAAGCATTTAATATTTATGCTCTTTAGAATGGAACACAGAAAACAAACCTTATAAGTCCTGATTAATCTGAACCAATAA CCTGTGTGGCCTACAAAGTATAATTCTATTAAATGTTCCTTAAAACACTTTTTTCTAATTAAAATCTTTGCAAATGCTTGTGTAACTTCC TGCCTTACAGCTACTTGTTTGCTGTGAGCCACCCGCAACTGACAAGTGGCTGTTAACTGAGTCACCATATCCCAGTAAAGCTGAATTTTC >In-frame_PRMT2_ENST00000440086_chr21_48069651_+_WRB_ENST00000541890_chr21_40762624_+_2052nt GTGGCTCAGGCTCCTGGAAAGGACCGTCCACCCCTCCGCGCTGGCGGTGTGGACGCGGAACTCAGCGGAGAAACGCGATTGAGAAATGGA AAAGAAAATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGG AGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCAC CGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGG CTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGG CAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGA ATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGT GTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTCCTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCA GAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCTGAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCA GAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATGAAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGC CAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTCAAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGAT AAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATGATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGT CGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCTACTAGAGTAGCAGTATTCTCCAGCAGTATTTGGACTTCCAA ATGTTTCTCTTCCCCTGATAAATCTATATTAGAAAAATAGGCAATTTAGTGCTGTTTAAAATGAATGGATCTCTATTTCAAGATGGCATG TCTAGTACACTTACGTGCACCGCCTCACAAGCACACTGAAATGACAGAAAAGGACACTATGAATTAGGACAATGGACTGAAAAATAAGCA GAAAATTTAAACACACCAGTGACCACAGTGCAACTGCAACTGACGATCAGTTTCCACCAAACTGCAACAGAGAGAGTGGCTTTGCCGTCT GGGCCAGCTGAGGACTCTCCTTGGAACCCAAAGAAGCAGTTTGTTTCCACCTACTCCCAAGAGCTGAAGATTATAAGCCAGAAGCAAACA AAGGCAGGCAAGGAAATTTGAGGTTGTTGCATCTGGAAGTAAACATGTAGCTACTTCTTCTAATAAAACAGAGTTCTATCTTTTGATTTG GTCTGGACACCTGGAGGTCAGCAACCGAGAGCAGGAAGGAGGCACAGCAACAACAGAACAACAACAAGAGGCTGCGACAGGGGCGGCGTG GGTCAAAAGGAAGCAACCTGGAGGACGGTCCTCCTTGCGGCTTGGAGCAGAGCTTCAGGTTGGGCACCACGACAGAGCTGGGCCAGAAGT CTAACACAGCCTGTTTGGAACACAACCCGGGATACTTGTGTGGTTGGGTTCAGTCAGTCAAGGGAAACAAGAAGCTAACCCGTGGCTGGG AGTGTTCATGCAATGCTCGTGGAATACTCAGCGCAAAGCCTGCCCGCAAGCACAAAGGGTATCAAGGAAGAGTTAAATGGGAAGTTGGGT >In-frame_PRMT2_ENST00000440086_chr21_48069651_+_WRB_ENST00000398753_chr21_40762624_+_1393nt GTGGCTCAGGCTCCTGGAAAGGACCGTCCACCCCTCCGCGCTGGCGGTGTGGACGCGGAACTCAGCGGAGAAACGCGATTGAGAAATGGA AAAGAAAATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGG AGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCAC CGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGG CTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGG CAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGA ATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGT GTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTCCTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCA GAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCTGAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCA GAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATGAAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGC CAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTCAAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGAT AAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATGATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGT CGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCTACTAGAGTAGCAGGTGGTGTTGGAATTACCTGTTGGATTTT AGTCTGTAACAAAGTTGTCGCTATTGTGCTTCATCCGTTCAGCTGAACAGGAGGATGGATACAGCCGCGAGGCTAAAAAACGGATTTCCT CTTCCTAGCTTAAAATCTGATTTACACTGTTTTGTTTTTTAAGAAACAAAAGTGCATAGTTTAGATTTTTTTTTTGTTGAATATGTTTGT >In-frame_PRMT2_ENST00000440086_chr21_48069651_+_WRB_ENST00000380708_chr21_40762624_+_2166nt GTGGCTCAGGCTCCTGGAAAGGACCGTCCACCCCTCCGCGCTGGCGGTGTGGACGCGGAACTCAGCGGAGAAACGCGATTGAGAAATGGA AAAGAAAATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGG AGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCAC CGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGG CTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGG CAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGA ATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGGT GTACGCGGTGGAGGCCAGTGAGATGGCACAGCACACGGGGCAGCTGGTCCTGCAGAACGGCTTTGCTGACATCATCACCGTGTACCAGCA GAAGGTGGAGGATGTGGTGCTGCCCGAGAAGGTGGACGTGCTGGTGTCTGAGTGGATGGGGACCTGCCTGCTGATGTCCAGGGTGCTGCA GAAGGACGCGGAGCAGGAGTCACAGATGAGAGCGGAGATCCAGGACATGAAGCAGGAGCTCTCCACAGTCAACATGATGGACGAGTTTGC CAGATATGCCAGGCTGGAAAGAAAGATCAACAAGATGACGGATAAGCTCAAAACCCATGTGAAAGCTCGGACAGCTCAATTAGCCAAGAT AAAATGGGTGATAAGTGTCGCTTTCTACGTATTGCAGGCTGCCCTGATGATCTCACTCATTTGGAAGTATTATTCTGTCCCTGTGGCTGT CGTGCCGAGTAAATGGATAACCCCTCTAGACCGCCTGGTAGCCTTTCCTACTAGAGTAGCAGGTGGTGTTGGAATTACCTGTTGGATTTT AGTCTGTAACAAAGTTGTCGCTATTGTGCTTCATCCGTTCAGCTGAACAGGAGGATGGATACAGCCGCGAGGCTAAAAAACGGATTTCCT CTTCCTAGCTTAAAATCTGATTTACACTGTTTTGTTTTTTAAGAAACAAAAGTGCATAGTTTAGATTTTTTTTTTGTTGAATATGTTTGT TCTTGGACTTTATGAGAGAGTCTTATAAGAATCACGATTTTCTACACCTGTCATTGAGCCAAGAAAGTCCAGTTTATGACACGTATGTAC TAGTGAACACCGTCCTCGATCTGTACGAAATGTGAAATGTTTAGGGACATCTCCATGCTGTCACTTGTGATTTGCCCTCTTATGTATTTT GGTCATATTGCCAACTGGAAAGTCAAAATTTTCTAACAACTTTAAGTAAGTTCTTTGAAGACTTAGTGCTGTTTTTAATCCAGTTTAGAA AGTAACTTAATTTTAATACCACTACTAAAAATTCGAAAATTTCTTCTTTAATCACATTCAATATGGTTAAAAGAACAACACTAATTGACA TTGCGTGGGCTTTTTCTCCCTTTGTTTAAAATGTCATTTGTTGAGCAAGAGTTGTATAGTATTATCTACTTACTTGAGGCTGTTAATTTT TCATTACAGTGTTTTGTAAATGTATCCACGAGACCATGATGCATTGTTTTGTGCTCAACTTGTGTTTTGTATTTAAAGCATTTTGAATGA AGTGTATTTTATAAGCATTTAATATTTATGCTCTTTAGAATGGAACACAGAAAACAAACCTTATAAGTCCTGATTAATCTGAACCAATAA CCTGTGTGGCCTACAAAGTATAATTCTATTAAATGTTCCTTAAAACACTTTTTTCTAATTAAAATCTTTGCAAATGCTTGTGTAACTTCC TGCCTTACAGCTACTTGTTTGCTGTGAGCCACCCGCAACTGACAAGTGGCTGTTAACTGAGTCACCATATCCCAGTAAAGCTGAATTTTC |
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FusionGenePPI for PRMT2_WRB |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| PRMT2 | PRRC2A, DMRTB1, CPSF7, HNRNPUL1, ESR1, HNRNPA1, RB1, E2F1, PSMB3, BAG6, FIP1L1, RIPK2, SPAG8, PSRC1, UBB, SALL2, GET4, SHANK3, HTT, TAB1, KANK2, LRFN1, PLEKHH3, POM121, SF1, L3MBTL3, TIGD5, KSR1, KRBA1, RBPMS, PPM1E, ANTXR1, TRAPPC2, SETD1B, SETD1A, PIK3R1, FHOD1, CXXC1, ERF, TTC28, SETD5, SAMD1, VCPIP1, C15orf39, MAP3K7, FASLG, CHEK2, UBR5, PIK3R2 | WRB | CAMLG, MCOLN3, FAS, SERPINA6, LPAR6, TOR3A, DPEP2, ERGIC3, ITGB8, HTR3C, CNDP1, DUSP6, ASNA1, SLC39A12, SLC22A9 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| Hgene | PRMT2 | chr21:48069651 | chr21:40762624 | ENST00000334494 | + | 6 | 7 | 83_207 | 218 | 285 | RB1 |
| Hgene | PRMT2 | chr21:48069651 | chr21:40762624 | ENST00000355680 | + | 7 | 12 | 83_207 | 218 | 434 | RB1 |
| Hgene | PRMT2 | chr21:48069651 | chr21:40762624 | ENST00000397637 | + | 6 | 11 | 83_207 | 218 | 434 | RB1 |
| Hgene | PRMT2 | chr21:48069651 | chr21:40762624 | ENST00000397638 | + | 6 | 11 | 83_207 | 218 | 434 | RB1 |
| Hgene | PRMT2 | chr21:48069651 | chr21:40762624 | ENST00000440086 | + | 6 | 9 | 83_207 | 218 | 332 | RB1 |
| Tgene | WRB | chr21:48069651 | chr21:40762624 | ENST00000333781 | + | 0 | 5 | 39_97 | 34 | 175 | ASNA1/TRC40 |
| Tgene | WRB | chr21:48069651 | chr21:40762624 | ENST00000380708 | + | 0 | 5 | 39_97 | 0 | 141 | ASNA1/TRC40 |
| Tgene | WRB | chr21:48069651 | chr21:40762624 | ENST00000398753 | + | 0 | 5 | 39_97 | 0 | 141 | ASNA1/TRC40 |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | PRMT2 | chr21:48069651 | chr21:40762624 | ENST00000334494 | + | 6 | 7 | 133_275 | 218 | 285 | ESR1 |
| Hgene | PRMT2 | chr21:48069651 | chr21:40762624 | ENST00000334494 | + | 6 | 7 | 1_277 | 218 | 285 | ESR1 |
| Hgene | PRMT2 | chr21:48069651 | chr21:40762624 | ENST00000355680 | + | 7 | 12 | 133_275 | 218 | 434 | ESR1 |
| Hgene | PRMT2 | chr21:48069651 | chr21:40762624 | ENST00000355680 | + | 7 | 12 | 1_277 | 218 | 434 | ESR1 |
| Hgene | PRMT2 | chr21:48069651 | chr21:40762624 | ENST00000397637 | + | 6 | 11 | 133_275 | 218 | 434 | ESR1 |
| Hgene | PRMT2 | chr21:48069651 | chr21:40762624 | ENST00000397637 | + | 6 | 11 | 1_277 | 218 | 434 | ESR1 |
| Hgene | PRMT2 | chr21:48069651 | chr21:40762624 | ENST00000397638 | + | 6 | 11 | 133_275 | 218 | 434 | ESR1 |
| Hgene | PRMT2 | chr21:48069651 | chr21:40762624 | ENST00000397638 | + | 6 | 11 | 1_277 | 218 | 434 | ESR1 |
| Hgene | PRMT2 | chr21:48069651 | chr21:40762624 | ENST00000440086 | + | 6 | 9 | 133_275 | 218 | 332 | ESR1 |
| Hgene | PRMT2 | chr21:48069651 | chr21:40762624 | ENST00000440086 | + | 6 | 9 | 1_277 | 218 | 332 | ESR1 |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for PRMT2_WRB |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for PRMT2_WRB |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | WRB | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |
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