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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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Fusion gene ID: 2874

FusionGeneSummary for ART3_SLC25A13

check button Fusion gene summary
Fusion gene informationFusion gene name: ART3_SLC25A13
Fusion gene ID: 2874
HgeneTgene
Gene symbol

ART3

SLC25A13

Gene ID

419

10165

Gene nameADP-ribosyltransferase 3solute carrier family 25 member 13
SynonymsARTC3ARALAR2|CITRIN|CTLN2
Cytomap

4q21.1|4p15.1-p14

7q21.3

Type of geneprotein-codingprotein-coding
Descriptionecto-ADP-ribosyltransferase 3ADP-ribosyltransferase C2 and C3 toxin-like 3NAD(P)(+)--arginine ADP-ribosyltransferase 3mono(ADP-ribosyl)transferase 3mono-ADP-ribosyltransferasecalcium-binding mitochondrial carrier protein Aralar2mitochondrial aspartate glutamate carrier 2solute carrier family 25 (aspartate/glutamate carrier), member 13
Modification date2018052320180523
UniProtAcc

Q13508

Q9UJS0

Ensembl transtripts involved in fusion geneENST00000341029, ENST00000355810, 
ENST00000349321, ENST00000513494, 
ENST00000265631, ENST00000416240, 
ENST00000542654, ENST00000494085, 
Fusion gene scores* DoF score4 X 4 X 2=327 X 6 X 5=210
# samples 47
** MAII scorelog2(4/32*10)=0.321928094887362
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(7/210*10)=-1.58496250072116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ART3 [Title/Abstract] AND SLC25A13 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneSLC25A13

GO:0006754

ATP biosynthetic process

12851387

TgeneSLC25A13

GO:0015810

aspartate transmembrane transport

11566871

TgeneSLC25A13

GO:0015813

L-glutamate transmembrane transport

11566871

TgeneSLC25A13

GO:0043490

malate-aspartate shuttle

11566871

TgeneSLC25A13

GO:0045333

cellular respiration

12851387

TgeneSLC25A13

GO:0051592

response to calcium ion

11566871


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVLUSCTCGA-43-7658-01AART3chr4

76997111

+SLC25A13chr7

95776008

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000341029ENST00000265631ART3chr4

76997111

+SLC25A13chr7

95776008

-
In-frameENST00000341029ENST00000416240ART3chr4

76997111

+SLC25A13chr7

95776008

-
In-frameENST00000341029ENST00000542654ART3chr4

76997111

+SLC25A13chr7

95776008

-
5CDS-intronENST00000341029ENST00000494085ART3chr4

76997111

+SLC25A13chr7

95776008

-
In-frameENST00000355810ENST00000265631ART3chr4

76997111

+SLC25A13chr7

95776008

-
In-frameENST00000355810ENST00000416240ART3chr4

76997111

+SLC25A13chr7

95776008

-
In-frameENST00000355810ENST00000542654ART3chr4

76997111

+SLC25A13chr7

95776008

-
5CDS-intronENST00000355810ENST00000494085ART3chr4

76997111

+SLC25A13chr7

95776008

-
In-frameENST00000349321ENST00000265631ART3chr4

76997111

+SLC25A13chr7

95776008

-
In-frameENST00000349321ENST00000416240ART3chr4

76997111

+SLC25A13chr7

95776008

-
In-frameENST00000349321ENST00000542654ART3chr4

76997111

+SLC25A13chr7

95776008

-
5CDS-intronENST00000349321ENST00000494085ART3chr4

76997111

+SLC25A13chr7

95776008

-
3UTR-3CDSENST00000513494ENST00000265631ART3chr4

76997111

+SLC25A13chr7

95776008

-
3UTR-3CDSENST00000513494ENST00000416240ART3chr4

76997111

+SLC25A13chr7

95776008

-
3UTR-3CDSENST00000513494ENST00000542654ART3chr4

76997111

+SLC25A13chr7

95776008

-
3UTR-intronENST00000513494ENST00000494085ART3chr4

76997111

+SLC25A13chr7

95776008

-

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FusionProtFeatures for ART3_SLC25A13


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ART3

Q13508

SLC25A13

Q9UJS0

Mitochondrial and calcium-binding carrier that catalyzesthe calcium-dependent exchange of cytoplasmic glutamate withmitochondrial aspartate across the mitochondrial inner membrane(PubMed:11566871, PubMed:25410934). May have a function in theurea cycle (PubMed:11566871). {ECO:0000269|PubMed:11566871,ECO:0000269|PubMed:25410934}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneSLC25A13chr4:76997111chr7:95776008ENST00000265631-1218613_675437676RegionC-terminal domain
TgeneSLC25A13chr4:76997111chr7:95776008ENST00000416240-1218613_675438677RegionC-terminal domain
TgeneSLC25A13chr4:76997111chr7:95776008ENST00000265631-1218518_606437676RepeatSolcar 3
TgeneSLC25A13chr4:76997111chr7:95776008ENST00000416240-1218518_606438677RepeatSolcar 3
TgeneSLC25A13chr4:76997111chr7:95776008ENST00000265631-1218436_449437676TransmembraneHelical%3B Name%3D3
TgeneSLC25A13chr4:76997111chr7:95776008ENST00000265631-1218485_504437676TransmembraneHelical%3B Name%3D4
TgeneSLC25A13chr4:76997111chr7:95776008ENST00000265631-1218524_541437676TransmembraneHelical%3B Name%3D5
TgeneSLC25A13chr4:76997111chr7:95776008ENST00000265631-1218581_600437676TransmembraneHelical%3B Name%3D6
TgeneSLC25A13chr4:76997111chr7:95776008ENST00000416240-1218436_449438677TransmembraneHelical%3B Name%3D3
TgeneSLC25A13chr4:76997111chr7:95776008ENST00000416240-1218485_504438677TransmembraneHelical%3B Name%3D4
TgeneSLC25A13chr4:76997111chr7:95776008ENST00000416240-1218524_541438677TransmembraneHelical%3B Name%3D5
TgeneSLC25A13chr4:76997111chr7:95776008ENST00000416240-1218581_600438677TransmembraneHelical%3B Name%3D6

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneART3chr4:76997111chr7:95776008ENST00000341029+210283_31223368RegionNote=3 X 10 AA tandem repeats of [GS]-E-K-N-[QW]-K-L-E-D-H
HgeneART3chr4:76997111chr7:95776008ENST00000349321+211283_31223379RegionNote=3 X 10 AA tandem repeats of [GS]-E-K-N-[QW]-K-L-E-D-H
HgeneART3chr4:76997111chr7:95776008ENST00000355810+212283_31223390RegionNote=3 X 10 AA tandem repeats of [GS]-E-K-N-[QW]-K-L-E-D-H
HgeneART3chr4:76997111chr7:95776008ENST00000341029+210283_29223368RepeatNote=1
HgeneART3chr4:76997111chr7:95776008ENST00000341029+210293_30223368RepeatNote=2
HgeneART3chr4:76997111chr7:95776008ENST00000341029+210303_31223368RepeatNote=3
HgeneART3chr4:76997111chr7:95776008ENST00000349321+211283_29223379RepeatNote=1
HgeneART3chr4:76997111chr7:95776008ENST00000349321+211293_30223379RepeatNote=2
HgeneART3chr4:76997111chr7:95776008ENST00000349321+211303_31223379RepeatNote=3
HgeneART3chr4:76997111chr7:95776008ENST00000355810+212283_29223390RepeatNote=1
HgeneART3chr4:76997111chr7:95776008ENST00000355810+212293_30223390RepeatNote=2
HgeneART3chr4:76997111chr7:95776008ENST00000355810+212303_31223390RepeatNote=3
TgeneSLC25A13chr4:76997111chr7:95776008ENST00000265631-1218100_111437676Calcium bindingNote=2
TgeneSLC25A13chr4:76997111chr7:95776008ENST00000265631-1218171_182437676Calcium bindingNote=3
TgeneSLC25A13chr4:76997111chr7:95776008ENST00000265631-121866_77437676Calcium binding1
TgeneSLC25A13chr4:76997111chr7:95776008ENST00000416240-1218100_111438677Calcium bindingNote=2
TgeneSLC25A13chr4:76997111chr7:95776008ENST00000416240-1218171_182438677Calcium bindingNote=3
TgeneSLC25A13chr4:76997111chr7:95776008ENST00000416240-121866_77438677Calcium binding1
TgeneSLC25A13chr4:76997111chr7:95776008ENST00000265631-1218125_157437676DomainEF-hand 3
TgeneSLC25A13chr4:76997111chr7:95776008ENST00000265631-1218158_193437676DomainEF-hand 4
TgeneSLC25A13chr4:76997111chr7:95776008ENST00000265631-121851_86437676DomainEF-hand 1
TgeneSLC25A13chr4:76997111chr7:95776008ENST00000265631-121887_122437676DomainEF-hand 2
TgeneSLC25A13chr4:76997111chr7:95776008ENST00000416240-1218125_157438677DomainEF-hand 3
TgeneSLC25A13chr4:76997111chr7:95776008ENST00000416240-1218158_193438677DomainEF-hand 4
TgeneSLC25A13chr4:76997111chr7:95776008ENST00000416240-121851_86438677DomainEF-hand 1
TgeneSLC25A13chr4:76997111chr7:95776008ENST00000416240-121887_122438677DomainEF-hand 2
TgeneSLC25A13chr4:76997111chr7:95776008ENST00000265631-1218296_311437676RegionLinker loop domain
TgeneSLC25A13chr4:76997111chr7:95776008ENST00000265631-12182_295437676RegionN-terminal domain
TgeneSLC25A13chr4:76997111chr7:95776008ENST00000265631-1218321_612437676RegionCarrier domain
TgeneSLC25A13chr4:76997111chr7:95776008ENST00000416240-1218296_311438677RegionLinker loop domain
TgeneSLC25A13chr4:76997111chr7:95776008ENST00000416240-12182_295438677RegionN-terminal domain
TgeneSLC25A13chr4:76997111chr7:95776008ENST00000416240-1218321_612438677RegionCarrier domain
TgeneSLC25A13chr4:76997111chr7:95776008ENST00000265631-1218326_418437676RepeatSolcar 1
TgeneSLC25A13chr4:76997111chr7:95776008ENST00000265631-1218426_510437676RepeatSolcar 2
TgeneSLC25A13chr4:76997111chr7:95776008ENST00000416240-1218326_418438677RepeatSolcar 1
TgeneSLC25A13chr4:76997111chr7:95776008ENST00000416240-1218426_510438677RepeatSolcar 2
TgeneSLC25A13chr4:76997111chr7:95776008ENST00000265631-1218332_349437676TransmembraneHelical%3B Name%3D1
TgeneSLC25A13chr4:76997111chr7:95776008ENST00000265631-1218393_412437676TransmembraneHelical%3B Name%3D2
TgeneSLC25A13chr4:76997111chr7:95776008ENST00000416240-1218332_349438677TransmembraneHelical%3B Name%3D1
TgeneSLC25A13chr4:76997111chr7:95776008ENST00000416240-1218393_412438677TransmembraneHelical%3B Name%3D2


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FusionGeneSequence for ART3_SLC25A13


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_ART3_ENST00000341029_chr4_76997111_+_SLC25A13_ENST00000265631_chr7_95776008_-_262aa
MKTGHFEIVTMLLATMILVDIFQAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCY
AHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFG

>In-frame_ART3_ENST00000341029_chr4_76997111_+_SLC25A13_ENST00000416240_chr7_95776008_-_262aa
MKTGHFEIVTMLLATMILVDIFQAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCY
AHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFG

>In-frame_ART3_ENST00000341029_chr4_76997111_+_SLC25A13_ENST00000542654_chr7_95776008_-_262aa
MKTGHFEIVTMLLATMILVDIFQAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCY
AHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFG

>In-frame_ART3_ENST00000355810_chr4_76997111_+_SLC25A13_ENST00000265631_chr7_95776008_-_262aa
MKTGHFEIVTMLLATMILVDIFQAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCY
AHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFG

>In-frame_ART3_ENST00000355810_chr4_76997111_+_SLC25A13_ENST00000416240_chr7_95776008_-_262aa
MKTGHFEIVTMLLATMILVDIFQAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCY
AHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFG

>In-frame_ART3_ENST00000355810_chr4_76997111_+_SLC25A13_ENST00000542654_chr7_95776008_-_262aa
MKTGHFEIVTMLLATMILVDIFQAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCY
AHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFG

>In-frame_ART3_ENST00000349321_chr4_76997111_+_SLC25A13_ENST00000265631_chr7_95776008_-_262aa
MKTGHFEIVTMLLATMILVDIFQAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCY
AHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFG

>In-frame_ART3_ENST00000349321_chr4_76997111_+_SLC25A13_ENST00000416240_chr7_95776008_-_262aa
MKTGHFEIVTMLLATMILVDIFQAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCY
AHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFG

>In-frame_ART3_ENST00000349321_chr4_76997111_+_SLC25A13_ENST00000542654_chr7_95776008_-_262aa
MKTGHFEIVTMLLATMILVDIFQAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCY
AHVKASFANEDGQVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFG


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_ART3_ENST00000341029_chr4_76997111_+_SLC25A13_ENST00000265631_chr7_95776008_-_786nt
ATGAAGACGGGACATTTTGAAATAGTCACCATGCTGCTGGCAACCATGATTCTAGTGGACATTTTCCAGGCTGGAGGCTCCCAGGTGATT
TTCACAAATCCTTTAGAAATCGTCAAGATCCGTTTGCAAGTGGCAGGAGAAATCACCACTGGTCCTCGAGTCAGTGCTCTGTCTGTCGTG
CGGGACCTGGGGTTTTTTGGGATCTACAAGGGTGCCAAAGCATGCTTTCTGCGGGACATTCCTTTCTCGGCCATCTACTTTCCGTGCTAT
GCTCATGTGAAGGCTTCCTTTGCAAATGAAGATGGGCAGGTTAGCCCAGGAAGCCTGCTCTTAGCTGGTGCCATAGCTGGTATGCCTGCA
GCATCTTTAGTGACCCCTGCTGATGTTATCAAGACGAGATTACAGGTGGCTGCCCGGGCTGGCCAAACCACTTACAGCGGAGTGATAGAC
TGCTTTAGAAAGATACTGCGTGAAGAAGGACCAAAAGCTCTGTGGAAGGGAGCTGGTGCTCGTGTATTTCGATCCTCACCCCAGTTTGGT
GTAACTTTGCTGACTTACGAATTGCTACAGCGATGGTTCTACATTGATTTTGGAGGAGTAAAACCCATGGGATCAGAGCCAGTTCCTAAA
TCCAGGATCAACCTGCCTGCCCCGAATCCTGATCACGTTGGGGGCTACAAACTGGCAGTTGCTACATTTGCAGGGATTGAAAACAAATTT

>In-frame_ART3_ENST00000341029_chr4_76997111_+_SLC25A13_ENST00000416240_chr7_95776008_-_786nt
ATGAAGACGGGACATTTTGAAATAGTCACCATGCTGCTGGCAACCATGATTCTAGTGGACATTTTCCAGGCTGGAGGCTCCCAGGTGATT
TTCACAAATCCTTTAGAAATCGTCAAGATCCGTTTGCAAGTGGCAGGAGAAATCACCACTGGTCCTCGAGTCAGTGCTCTGTCTGTCGTG
CGGGACCTGGGGTTTTTTGGGATCTACAAGGGTGCCAAAGCATGCTTTCTGCGGGACATTCCTTTCTCGGCCATCTACTTTCCGTGCTAT
GCTCATGTGAAGGCTTCCTTTGCAAATGAAGATGGGCAGGTTAGCCCAGGAAGCCTGCTCTTAGCTGGTGCCATAGCTGGTATGCCTGCA
GCATCTTTAGTGACCCCTGCTGATGTTATCAAGACGAGATTACAGGTGGCTGCCCGGGCTGGCCAAACCACTTACAGCGGAGTGATAGAC
TGCTTTAGAAAGATACTGCGTGAAGAAGGACCAAAAGCTCTGTGGAAGGGAGCTGGTGCTCGTGTATTTCGATCCTCACCCCAGTTTGGT
GTAACTTTGCTGACTTACGAATTGCTACAGCGATGGTTCTACATTGATTTTGGAGGAGTAAAACCCATGGGATCAGAGCCAGTTCCTAAA
TCCAGGATCAACCTGCCTGCCCCGAATCCTGATCACGTTGGGGGCTACAAACTGGCAGTTGCTACATTTGCAGGGATTGAAAACAAATTT

>In-frame_ART3_ENST00000341029_chr4_76997111_+_SLC25A13_ENST00000542654_chr7_95776008_-_786nt
ATGAAGACGGGACATTTTGAAATAGTCACCATGCTGCTGGCAACCATGATTCTAGTGGACATTTTCCAGGCTGGAGGCTCCCAGGTGATT
TTCACAAATCCTTTAGAAATCGTCAAGATCCGTTTGCAAGTGGCAGGAGAAATCACCACTGGTCCTCGAGTCAGTGCTCTGTCTGTCGTG
CGGGACCTGGGGTTTTTTGGGATCTACAAGGGTGCCAAAGCATGCTTTCTGCGGGACATTCCTTTCTCGGCCATCTACTTTCCGTGCTAT
GCTCATGTGAAGGCTTCCTTTGCAAATGAAGATGGGCAGGTTAGCCCAGGAAGCCTGCTCTTAGCTGGTGCCATAGCTGGTATGCCTGCA
GCATCTTTAGTGACCCCTGCTGATGTTATCAAGACGAGATTACAGGTGGCTGCCCGGGCTGGCCAAACCACTTACAGCGGAGTGATAGAC
TGCTTTAGAAAGATACTGCGTGAAGAAGGACCAAAAGCTCTGTGGAAGGGAGCTGGTGCTCGTGTATTTCGATCCTCACCCCAGTTTGGT
GTAACTTTGCTGACTTACGAATTGCTACAGCGATGGTTCTACATTGATTTTGGAGGAGTAAAACCCATGGGATCAGAGCCAGTTCCTAAA
TCCAGGATCAACCTGCCTGCCCCGAATCCTGATCACGTTGGGGGCTACAAACTGGCAGTTGCTACATTTGCAGGGATTGAAAACAAATTT

>In-frame_ART3_ENST00000355810_chr4_76997111_+_SLC25A13_ENST00000265631_chr7_95776008_-_786nt
ATGAAGACGGGACATTTTGAAATAGTCACCATGCTGCTGGCAACCATGATTCTAGTGGACATTTTCCAGGCTGGAGGCTCCCAGGTGATT
TTCACAAATCCTTTAGAAATCGTCAAGATCCGTTTGCAAGTGGCAGGAGAAATCACCACTGGTCCTCGAGTCAGTGCTCTGTCTGTCGTG
CGGGACCTGGGGTTTTTTGGGATCTACAAGGGTGCCAAAGCATGCTTTCTGCGGGACATTCCTTTCTCGGCCATCTACTTTCCGTGCTAT
GCTCATGTGAAGGCTTCCTTTGCAAATGAAGATGGGCAGGTTAGCCCAGGAAGCCTGCTCTTAGCTGGTGCCATAGCTGGTATGCCTGCA
GCATCTTTAGTGACCCCTGCTGATGTTATCAAGACGAGATTACAGGTGGCTGCCCGGGCTGGCCAAACCACTTACAGCGGAGTGATAGAC
TGCTTTAGAAAGATACTGCGTGAAGAAGGACCAAAAGCTCTGTGGAAGGGAGCTGGTGCTCGTGTATTTCGATCCTCACCCCAGTTTGGT
GTAACTTTGCTGACTTACGAATTGCTACAGCGATGGTTCTACATTGATTTTGGAGGAGTAAAACCCATGGGATCAGAGCCAGTTCCTAAA
TCCAGGATCAACCTGCCTGCCCCGAATCCTGATCACGTTGGGGGCTACAAACTGGCAGTTGCTACATTTGCAGGGATTGAAAACAAATTT

>In-frame_ART3_ENST00000355810_chr4_76997111_+_SLC25A13_ENST00000416240_chr7_95776008_-_786nt
ATGAAGACGGGACATTTTGAAATAGTCACCATGCTGCTGGCAACCATGATTCTAGTGGACATTTTCCAGGCTGGAGGCTCCCAGGTGATT
TTCACAAATCCTTTAGAAATCGTCAAGATCCGTTTGCAAGTGGCAGGAGAAATCACCACTGGTCCTCGAGTCAGTGCTCTGTCTGTCGTG
CGGGACCTGGGGTTTTTTGGGATCTACAAGGGTGCCAAAGCATGCTTTCTGCGGGACATTCCTTTCTCGGCCATCTACTTTCCGTGCTAT
GCTCATGTGAAGGCTTCCTTTGCAAATGAAGATGGGCAGGTTAGCCCAGGAAGCCTGCTCTTAGCTGGTGCCATAGCTGGTATGCCTGCA
GCATCTTTAGTGACCCCTGCTGATGTTATCAAGACGAGATTACAGGTGGCTGCCCGGGCTGGCCAAACCACTTACAGCGGAGTGATAGAC
TGCTTTAGAAAGATACTGCGTGAAGAAGGACCAAAAGCTCTGTGGAAGGGAGCTGGTGCTCGTGTATTTCGATCCTCACCCCAGTTTGGT
GTAACTTTGCTGACTTACGAATTGCTACAGCGATGGTTCTACATTGATTTTGGAGGAGTAAAACCCATGGGATCAGAGCCAGTTCCTAAA
TCCAGGATCAACCTGCCTGCCCCGAATCCTGATCACGTTGGGGGCTACAAACTGGCAGTTGCTACATTTGCAGGGATTGAAAACAAATTT

>In-frame_ART3_ENST00000355810_chr4_76997111_+_SLC25A13_ENST00000542654_chr7_95776008_-_786nt
ATGAAGACGGGACATTTTGAAATAGTCACCATGCTGCTGGCAACCATGATTCTAGTGGACATTTTCCAGGCTGGAGGCTCCCAGGTGATT
TTCACAAATCCTTTAGAAATCGTCAAGATCCGTTTGCAAGTGGCAGGAGAAATCACCACTGGTCCTCGAGTCAGTGCTCTGTCTGTCGTG
CGGGACCTGGGGTTTTTTGGGATCTACAAGGGTGCCAAAGCATGCTTTCTGCGGGACATTCCTTTCTCGGCCATCTACTTTCCGTGCTAT
GCTCATGTGAAGGCTTCCTTTGCAAATGAAGATGGGCAGGTTAGCCCAGGAAGCCTGCTCTTAGCTGGTGCCATAGCTGGTATGCCTGCA
GCATCTTTAGTGACCCCTGCTGATGTTATCAAGACGAGATTACAGGTGGCTGCCCGGGCTGGCCAAACCACTTACAGCGGAGTGATAGAC
TGCTTTAGAAAGATACTGCGTGAAGAAGGACCAAAAGCTCTGTGGAAGGGAGCTGGTGCTCGTGTATTTCGATCCTCACCCCAGTTTGGT
GTAACTTTGCTGACTTACGAATTGCTACAGCGATGGTTCTACATTGATTTTGGAGGAGTAAAACCCATGGGATCAGAGCCAGTTCCTAAA
TCCAGGATCAACCTGCCTGCCCCGAATCCTGATCACGTTGGGGGCTACAAACTGGCAGTTGCTACATTTGCAGGGATTGAAAACAAATTT

>In-frame_ART3_ENST00000349321_chr4_76997111_+_SLC25A13_ENST00000265631_chr7_95776008_-_786nt
ATGAAGACGGGACATTTTGAAATAGTCACCATGCTGCTGGCAACCATGATTCTAGTGGACATTTTCCAGGCTGGAGGCTCCCAGGTGATT
TTCACAAATCCTTTAGAAATCGTCAAGATCCGTTTGCAAGTGGCAGGAGAAATCACCACTGGTCCTCGAGTCAGTGCTCTGTCTGTCGTG
CGGGACCTGGGGTTTTTTGGGATCTACAAGGGTGCCAAAGCATGCTTTCTGCGGGACATTCCTTTCTCGGCCATCTACTTTCCGTGCTAT
GCTCATGTGAAGGCTTCCTTTGCAAATGAAGATGGGCAGGTTAGCCCAGGAAGCCTGCTCTTAGCTGGTGCCATAGCTGGTATGCCTGCA
GCATCTTTAGTGACCCCTGCTGATGTTATCAAGACGAGATTACAGGTGGCTGCCCGGGCTGGCCAAACCACTTACAGCGGAGTGATAGAC
TGCTTTAGAAAGATACTGCGTGAAGAAGGACCAAAAGCTCTGTGGAAGGGAGCTGGTGCTCGTGTATTTCGATCCTCACCCCAGTTTGGT
GTAACTTTGCTGACTTACGAATTGCTACAGCGATGGTTCTACATTGATTTTGGAGGAGTAAAACCCATGGGATCAGAGCCAGTTCCTAAA
TCCAGGATCAACCTGCCTGCCCCGAATCCTGATCACGTTGGGGGCTACAAACTGGCAGTTGCTACATTTGCAGGGATTGAAAACAAATTT

>In-frame_ART3_ENST00000349321_chr4_76997111_+_SLC25A13_ENST00000416240_chr7_95776008_-_786nt
ATGAAGACGGGACATTTTGAAATAGTCACCATGCTGCTGGCAACCATGATTCTAGTGGACATTTTCCAGGCTGGAGGCTCCCAGGTGATT
TTCACAAATCCTTTAGAAATCGTCAAGATCCGTTTGCAAGTGGCAGGAGAAATCACCACTGGTCCTCGAGTCAGTGCTCTGTCTGTCGTG
CGGGACCTGGGGTTTTTTGGGATCTACAAGGGTGCCAAAGCATGCTTTCTGCGGGACATTCCTTTCTCGGCCATCTACTTTCCGTGCTAT
GCTCATGTGAAGGCTTCCTTTGCAAATGAAGATGGGCAGGTTAGCCCAGGAAGCCTGCTCTTAGCTGGTGCCATAGCTGGTATGCCTGCA
GCATCTTTAGTGACCCCTGCTGATGTTATCAAGACGAGATTACAGGTGGCTGCCCGGGCTGGCCAAACCACTTACAGCGGAGTGATAGAC
TGCTTTAGAAAGATACTGCGTGAAGAAGGACCAAAAGCTCTGTGGAAGGGAGCTGGTGCTCGTGTATTTCGATCCTCACCCCAGTTTGGT
GTAACTTTGCTGACTTACGAATTGCTACAGCGATGGTTCTACATTGATTTTGGAGGAGTAAAACCCATGGGATCAGAGCCAGTTCCTAAA
TCCAGGATCAACCTGCCTGCCCCGAATCCTGATCACGTTGGGGGCTACAAACTGGCAGTTGCTACATTTGCAGGGATTGAAAACAAATTT

>In-frame_ART3_ENST00000349321_chr4_76997111_+_SLC25A13_ENST00000542654_chr7_95776008_-_786nt
ATGAAGACGGGACATTTTGAAATAGTCACCATGCTGCTGGCAACCATGATTCTAGTGGACATTTTCCAGGCTGGAGGCTCCCAGGTGATT
TTCACAAATCCTTTAGAAATCGTCAAGATCCGTTTGCAAGTGGCAGGAGAAATCACCACTGGTCCTCGAGTCAGTGCTCTGTCTGTCGTG
CGGGACCTGGGGTTTTTTGGGATCTACAAGGGTGCCAAAGCATGCTTTCTGCGGGACATTCCTTTCTCGGCCATCTACTTTCCGTGCTAT
GCTCATGTGAAGGCTTCCTTTGCAAATGAAGATGGGCAGGTTAGCCCAGGAAGCCTGCTCTTAGCTGGTGCCATAGCTGGTATGCCTGCA
GCATCTTTAGTGACCCCTGCTGATGTTATCAAGACGAGATTACAGGTGGCTGCCCGGGCTGGCCAAACCACTTACAGCGGAGTGATAGAC
TGCTTTAGAAAGATACTGCGTGAAGAAGGACCAAAAGCTCTGTGGAAGGGAGCTGGTGCTCGTGTATTTCGATCCTCACCCCAGTTTGGT
GTAACTTTGCTGACTTACGAATTGCTACAGCGATGGTTCTACATTGATTTTGGAGGAGTAAAACCCATGGGATCAGAGCCAGTTCCTAAA
TCCAGGATCAACCTGCCTGCCCCGAATCCTGATCACGTTGGGGGCTACAAACTGGCAGTTGCTACATTTGCAGGGATTGAAAACAAATTT


* Fusion transcript sequences (Full-length transcript).
>In-frame_ART3_ENST00000341029_chr4_76997111_+_SLC25A13_ENST00000265631_chr7_95776008_-_1887nt
AGTGAGGAGGTTATACCCGGAGGTCTCGACGCTCGCTCGTGCTGCTCGTGTTGCCGCTGGGTACGTTTGCTGCCAGTGCTGATCCAGCCG
GAGGCGAAGAGAAGCACTTTGGGGGCAAAAGAAGAGAAAAATGAAGACGGGACATTTTGAAATAGTCACCATGCTGCTGGCAACCATGAT
TCTAGTGGACATTTTCCAGGCTGGAGGCTCCCAGGTGATTTTCACAAATCCTTTAGAAATCGTCAAGATCCGTTTGCAAGTGGCAGGAGA
AATCACCACTGGTCCTCGAGTCAGTGCTCTGTCTGTCGTGCGGGACCTGGGGTTTTTTGGGATCTACAAGGGTGCCAAAGCATGCTTTCT
GCGGGACATTCCTTTCTCGGCCATCTACTTTCCGTGCTATGCTCATGTGAAGGCTTCCTTTGCAAATGAAGATGGGCAGGTTAGCCCAGG
AAGCCTGCTCTTAGCTGGTGCCATAGCTGGTATGCCTGCAGCATCTTTAGTGACCCCTGCTGATGTTATCAAGACGAGATTACAGGTGGC
TGCCCGGGCTGGCCAAACCACTTACAGCGGAGTGATAGACTGCTTTAGAAAGATACTGCGTGAAGAAGGACCAAAAGCTCTGTGGAAGGG
AGCTGGTGCTCGTGTATTTCGATCCTCACCCCAGTTTGGTGTAACTTTGCTGACTTACGAATTGCTACAGCGATGGTTCTACATTGATTT
TGGAGGAGTAAAACCCATGGGATCAGAGCCAGTTCCTAAATCCAGGATCAACCTGCCTGCCCCGAATCCTGATCACGTTGGGGGCTACAA
ACTGGCAGTTGCTACATTTGCAGGGATTGAAAACAAATTTGGACTTTACCTACCTCTCTTCAAGCCATCAGTATCTACCTCAAAGGCTAT
TGGTGGAGGCCCATAGGAAGATCAGCCCTGGGATAGTGCTGTCTTTTTGTGGGTACTGCAGTAAAGAACATCCCTCCTGGGAATGAAGCA
ATGCTTCATCCCTTTTACGTCCATCTCTTGTTTAAATTCAAGTCCAGGCTTTTTTATCATGTGAAATCATTCATTTTCTGGGTGTTTTCT
TAACCAGATCATTGTGAAATTATTCATAATTATTATTTGGCCCTCTGCCCAGAAACCTTTGTTTGCATCTGAAAATTGATGGGATTTGGT
CAACACTAACATGATTTGGGGAAAGGAGCAAGTCAGAATAGAAATTAGTACTCCCCTCCTTGAACTAGGATTGTAGTCCCAAAGAGGCTA
CTGTAAGGCAATCATGGTGCTCAGAGCAGTGTTTCGTGTGTGTTTTAAACTGGTAGGAAACTAGGTGCATATTTATAAAAATAAAAAACA
CTGGGAGAAATGAAAAAATATATATCAAATATATTCAGCCTGGCTTCAAATTGTAAGCATGCACAAATTCTGTCTCTGGATTATATTATG
AAGCTTTTATGTGAAACATGTTTCTTTGTAATGAAAACCACATTGGAGATGTTTAGTAATCATATTGTTACTGGTACCAAGACTACTAGG
GAAATGCCTTTGTACTTTAGGGAAGTACTTTTGGCATTTTACTGTACAGACAGAAAAAACTGAGATGTAGCCCCTCTCCTGGAAGTGCTA
ATTTTGAAAAACTGCTCATATGATGTACATGTACTGATTACTGCCTATTTTAATAAACACTCTTGAAAAATGCATGTTGCCCTGTTGCTG
CCTGCCCTATTCTCCTCATCTCCCCATCATTGGTACCCACTTGCTTTTAAAATCCACTTTATCTTGAATAATGTAAGACAAATATGTTCT

>In-frame_ART3_ENST00000341029_chr4_76997111_+_SLC25A13_ENST00000416240_chr7_95776008_-_1886nt
AGTGAGGAGGTTATACCCGGAGGTCTCGACGCTCGCTCGTGCTGCTCGTGTTGCCGCTGGGTACGTTTGCTGCCAGTGCTGATCCAGCCG
GAGGCGAAGAGAAGCACTTTGGGGGCAAAAGAAGAGAAAAATGAAGACGGGACATTTTGAAATAGTCACCATGCTGCTGGCAACCATGAT
TCTAGTGGACATTTTCCAGGCTGGAGGCTCCCAGGTGATTTTCACAAATCCTTTAGAAATCGTCAAGATCCGTTTGCAAGTGGCAGGAGA
AATCACCACTGGTCCTCGAGTCAGTGCTCTGTCTGTCGTGCGGGACCTGGGGTTTTTTGGGATCTACAAGGGTGCCAAAGCATGCTTTCT
GCGGGACATTCCTTTCTCGGCCATCTACTTTCCGTGCTATGCTCATGTGAAGGCTTCCTTTGCAAATGAAGATGGGCAGGTTAGCCCAGG
AAGCCTGCTCTTAGCTGGTGCCATAGCTGGTATGCCTGCAGCATCTTTAGTGACCCCTGCTGATGTTATCAAGACGAGATTACAGGTGGC
TGCCCGGGCTGGCCAAACCACTTACAGCGGAGTGATAGACTGCTTTAGAAAGATACTGCGTGAAGAAGGACCAAAAGCTCTGTGGAAGGG
AGCTGGTGCTCGTGTATTTCGATCCTCACCCCAGTTTGGTGTAACTTTGCTGACTTACGAATTGCTACAGCGATGGTTCTACATTGATTT
TGGAGGAGTAAAACCCATGGGATCAGAGCCAGTTCCTAAATCCAGGATCAACCTGCCTGCCCCGAATCCTGATCACGTTGGGGGCTACAA
ACTGGCAGTTGCTACATTTGCAGGGATTGAAAACAAATTTGGACTTTACCTACCTCTCTTCAAGCCATCAGTATCTACCTCAAAGGCTAT
TGGTGGAGGCCCATAGGAAGATCAGCCCTGGGATAGTGCTGTCTTTTTGTGGGTACTGCAGTAAAGAACATCCCTCCTGGGAATGAAGCA
ATGCTTCATCCCTTTTACGTCCATCTCTTGTTTAAATTCAAGTCCAGGCTTTTTTATCATGTGAAATCATTCATTTTCTGGGTGTTTTCT
TAACCAGATCATTGTGAAATTATTCATAATTATTATTTGGCCCTCTGCCCAGAAACCTTTGTTTGCATCTGAAAATTGATGGGATTTGGT
CAACACTAACATGATTTGGGGAAAGGAGCAAGTCAGAATAGAAATTAGTACTCCCCTCCTTGAACTAGGATTGTAGTCCCAAAGAGGCTA
CTGTAAGGCAATCATGGTGCTCAGAGCAGTGTTTCGTGTGTGTTTTAAACTGGTAGGAAACTAGGTGCATATTTATAAAAATAAAAAACA
CTGGGAGAAATGAAAAAATATATATCAAATATATTCAGCCTGGCTTCAAATTGTAAGCATGCACAAATTCTGTCTCTGGATTATATTATG
AAGCTTTTATGTGAAACATGTTTCTTTGTAATGAAAACCACATTGGAGATGTTTAGTAATCATATTGTTACTGGTACCAAGACTACTAGG
GAAATGCCTTTGTACTTTAGGGAAGTACTTTTGGCATTTTACTGTACAGACAGAAAAAACTGAGATGTAGCCCCTCTCCTGGAAGTGCTA
ATTTTGAAAAACTGCTCATATGATGTACATGTACTGATTACTGCCTATTTTAATAAACACTCTTGAAAAATGCATGTTGCCCTGTTGCTG
CCTGCCCTATTCTCCTCATCTCCCCATCATTGGTACCCACTTGCTTTTAAAATCCACTTTATCTTGAATAATGTAAGACAAATATGTTCT

>In-frame_ART3_ENST00000341029_chr4_76997111_+_SLC25A13_ENST00000542654_chr7_95776008_-_1207nt
AGTGAGGAGGTTATACCCGGAGGTCTCGACGCTCGCTCGTGCTGCTCGTGTTGCCGCTGGGTACGTTTGCTGCCAGTGCTGATCCAGCCG
GAGGCGAAGAGAAGCACTTTGGGGGCAAAAGAAGAGAAAAATGAAGACGGGACATTTTGAAATAGTCACCATGCTGCTGGCAACCATGAT
TCTAGTGGACATTTTCCAGGCTGGAGGCTCCCAGGTGATTTTCACAAATCCTTTAGAAATCGTCAAGATCCGTTTGCAAGTGGCAGGAGA
AATCACCACTGGTCCTCGAGTCAGTGCTCTGTCTGTCGTGCGGGACCTGGGGTTTTTTGGGATCTACAAGGGTGCCAAAGCATGCTTTCT
GCGGGACATTCCTTTCTCGGCCATCTACTTTCCGTGCTATGCTCATGTGAAGGCTTCCTTTGCAAATGAAGATGGGCAGGTTAGCCCAGG
AAGCCTGCTCTTAGCTGGTGCCATAGCTGGTATGCCTGCAGCATCTTTAGTGACCCCTGCTGATGTTATCAAGACGAGATTACAGGTGGC
TGCCCGGGCTGGCCAAACCACTTACAGCGGAGTGATAGACTGCTTTAGAAAGATACTGCGTGAAGAAGGACCAAAAGCTCTGTGGAAGGG
AGCTGGTGCTCGTGTATTTCGATCCTCACCCCAGTTTGGTGTAACTTTGCTGACTTACGAATTGCTACAGCGATGGTTCTACATTGATTT
TGGAGGAGTAAAACCCATGGGATCAGAGCCAGTTCCTAAATCCAGGATCAACCTGCCTGCCCCGAATCCTGATCACGTTGGGGGCTACAA
ACTGGCAGTTGCTACATTTGCAGGGATTGAAAACAAATTTGGACTTTACCTACCTCTCTTCAAGCCATCAGTATCTACCTCAAAGGCTAT
TGGTGGAGGCCCATAGGAAGATCAGCCCTGGGATAGTGCTGTCTTTTTGTGGGTACTGCAGTAAAGAACATCCCTCCTGGGAATGAAGCA
ATGCTTCATCCCTTTTACGTCCATCTCTTGTTTAAATTCAAGTCCAGGCTTTTTTATCATGTGAAATCATTCATTTTCTGGGTGTTTTCT
TAACCAGATCATTGTGAAATTATTCATAATTATTATTTGGCCCTCTGCCCAGAAACCTTTGTTTGCATCTGAAAATTGATGGGATTTGGT

>In-frame_ART3_ENST00000355810_chr4_76997111_+_SLC25A13_ENST00000265631_chr7_95776008_-_1876nt
CTCACTGTCAACAACATCCCATCCTGAAGACTTGCTTACCACAACTGAGAGTGGGGAGTCAGTTTGAGGCCTAGCATCACTTAAACTTCC
TCCAAAGGCACAAAAGCCAGAAGAGAAAAATGAAGACGGGACATTTTGAAATAGTCACCATGCTGCTGGCAACCATGATTCTAGTGGACA
TTTTCCAGGCTGGAGGCTCCCAGGTGATTTTCACAAATCCTTTAGAAATCGTCAAGATCCGTTTGCAAGTGGCAGGAGAAATCACCACTG
GTCCTCGAGTCAGTGCTCTGTCTGTCGTGCGGGACCTGGGGTTTTTTGGGATCTACAAGGGTGCCAAAGCATGCTTTCTGCGGGACATTC
CTTTCTCGGCCATCTACTTTCCGTGCTATGCTCATGTGAAGGCTTCCTTTGCAAATGAAGATGGGCAGGTTAGCCCAGGAAGCCTGCTCT
TAGCTGGTGCCATAGCTGGTATGCCTGCAGCATCTTTAGTGACCCCTGCTGATGTTATCAAGACGAGATTACAGGTGGCTGCCCGGGCTG
GCCAAACCACTTACAGCGGAGTGATAGACTGCTTTAGAAAGATACTGCGTGAAGAAGGACCAAAAGCTCTGTGGAAGGGAGCTGGTGCTC
GTGTATTTCGATCCTCACCCCAGTTTGGTGTAACTTTGCTGACTTACGAATTGCTACAGCGATGGTTCTACATTGATTTTGGAGGAGTAA
AACCCATGGGATCAGAGCCAGTTCCTAAATCCAGGATCAACCTGCCTGCCCCGAATCCTGATCACGTTGGGGGCTACAAACTGGCAGTTG
CTACATTTGCAGGGATTGAAAACAAATTTGGACTTTACCTACCTCTCTTCAAGCCATCAGTATCTACCTCAAAGGCTATTGGTGGAGGCC
CATAGGAAGATCAGCCCTGGGATAGTGCTGTCTTTTTGTGGGTACTGCAGTAAAGAACATCCCTCCTGGGAATGAAGCAATGCTTCATCC
CTTTTACGTCCATCTCTTGTTTAAATTCAAGTCCAGGCTTTTTTATCATGTGAAATCATTCATTTTCTGGGTGTTTTCTTAACCAGATCA
TTGTGAAATTATTCATAATTATTATTTGGCCCTCTGCCCAGAAACCTTTGTTTGCATCTGAAAATTGATGGGATTTGGTCAACACTAACA
TGATTTGGGGAAAGGAGCAAGTCAGAATAGAAATTAGTACTCCCCTCCTTGAACTAGGATTGTAGTCCCAAAGAGGCTACTGTAAGGCAA
TCATGGTGCTCAGAGCAGTGTTTCGTGTGTGTTTTAAACTGGTAGGAAACTAGGTGCATATTTATAAAAATAAAAAACACTGGGAGAAAT
GAAAAAATATATATCAAATATATTCAGCCTGGCTTCAAATTGTAAGCATGCACAAATTCTGTCTCTGGATTATATTATGAAGCTTTTATG
TGAAACATGTTTCTTTGTAATGAAAACCACATTGGAGATGTTTAGTAATCATATTGTTACTGGTACCAAGACTACTAGGGAAATGCCTTT
GTACTTTAGGGAAGTACTTTTGGCATTTTACTGTACAGACAGAAAAAACTGAGATGTAGCCCCTCTCCTGGAAGTGCTAATTTTGAAAAA
CTGCTCATATGATGTACATGTACTGATTACTGCCTATTTTAATAAACACTCTTGAAAAATGCATGTTGCCCTGTTGCTGCCTGCCCTATT
CTCCTCATCTCCCCATCATTGGTACCCACTTGCTTTTAAAATCCACTTTATCTTGAATAATGTAAGACAAATATGTTCTGACATAAGTAT

>In-frame_ART3_ENST00000355810_chr4_76997111_+_SLC25A13_ENST00000416240_chr7_95776008_-_1875nt
CTCACTGTCAACAACATCCCATCCTGAAGACTTGCTTACCACAACTGAGAGTGGGGAGTCAGTTTGAGGCCTAGCATCACTTAAACTTCC
TCCAAAGGCACAAAAGCCAGAAGAGAAAAATGAAGACGGGACATTTTGAAATAGTCACCATGCTGCTGGCAACCATGATTCTAGTGGACA
TTTTCCAGGCTGGAGGCTCCCAGGTGATTTTCACAAATCCTTTAGAAATCGTCAAGATCCGTTTGCAAGTGGCAGGAGAAATCACCACTG
GTCCTCGAGTCAGTGCTCTGTCTGTCGTGCGGGACCTGGGGTTTTTTGGGATCTACAAGGGTGCCAAAGCATGCTTTCTGCGGGACATTC
CTTTCTCGGCCATCTACTTTCCGTGCTATGCTCATGTGAAGGCTTCCTTTGCAAATGAAGATGGGCAGGTTAGCCCAGGAAGCCTGCTCT
TAGCTGGTGCCATAGCTGGTATGCCTGCAGCATCTTTAGTGACCCCTGCTGATGTTATCAAGACGAGATTACAGGTGGCTGCCCGGGCTG
GCCAAACCACTTACAGCGGAGTGATAGACTGCTTTAGAAAGATACTGCGTGAAGAAGGACCAAAAGCTCTGTGGAAGGGAGCTGGTGCTC
GTGTATTTCGATCCTCACCCCAGTTTGGTGTAACTTTGCTGACTTACGAATTGCTACAGCGATGGTTCTACATTGATTTTGGAGGAGTAA
AACCCATGGGATCAGAGCCAGTTCCTAAATCCAGGATCAACCTGCCTGCCCCGAATCCTGATCACGTTGGGGGCTACAAACTGGCAGTTG
CTACATTTGCAGGGATTGAAAACAAATTTGGACTTTACCTACCTCTCTTCAAGCCATCAGTATCTACCTCAAAGGCTATTGGTGGAGGCC
CATAGGAAGATCAGCCCTGGGATAGTGCTGTCTTTTTGTGGGTACTGCAGTAAAGAACATCCCTCCTGGGAATGAAGCAATGCTTCATCC
CTTTTACGTCCATCTCTTGTTTAAATTCAAGTCCAGGCTTTTTTATCATGTGAAATCATTCATTTTCTGGGTGTTTTCTTAACCAGATCA
TTGTGAAATTATTCATAATTATTATTTGGCCCTCTGCCCAGAAACCTTTGTTTGCATCTGAAAATTGATGGGATTTGGTCAACACTAACA
TGATTTGGGGAAAGGAGCAAGTCAGAATAGAAATTAGTACTCCCCTCCTTGAACTAGGATTGTAGTCCCAAAGAGGCTACTGTAAGGCAA
TCATGGTGCTCAGAGCAGTGTTTCGTGTGTGTTTTAAACTGGTAGGAAACTAGGTGCATATTTATAAAAATAAAAAACACTGGGAGAAAT
GAAAAAATATATATCAAATATATTCAGCCTGGCTTCAAATTGTAAGCATGCACAAATTCTGTCTCTGGATTATATTATGAAGCTTTTATG
TGAAACATGTTTCTTTGTAATGAAAACCACATTGGAGATGTTTAGTAATCATATTGTTACTGGTACCAAGACTACTAGGGAAATGCCTTT
GTACTTTAGGGAAGTACTTTTGGCATTTTACTGTACAGACAGAAAAAACTGAGATGTAGCCCCTCTCCTGGAAGTGCTAATTTTGAAAAA
CTGCTCATATGATGTACATGTACTGATTACTGCCTATTTTAATAAACACTCTTGAAAAATGCATGTTGCCCTGTTGCTGCCTGCCCTATT
CTCCTCATCTCCCCATCATTGGTACCCACTTGCTTTTAAAATCCACTTTATCTTGAATAATGTAAGACAAATATGTTCTGACATAAGTAT

>In-frame_ART3_ENST00000355810_chr4_76997111_+_SLC25A13_ENST00000542654_chr7_95776008_-_1196nt
CTCACTGTCAACAACATCCCATCCTGAAGACTTGCTTACCACAACTGAGAGTGGGGAGTCAGTTTGAGGCCTAGCATCACTTAAACTTCC
TCCAAAGGCACAAAAGCCAGAAGAGAAAAATGAAGACGGGACATTTTGAAATAGTCACCATGCTGCTGGCAACCATGATTCTAGTGGACA
TTTTCCAGGCTGGAGGCTCCCAGGTGATTTTCACAAATCCTTTAGAAATCGTCAAGATCCGTTTGCAAGTGGCAGGAGAAATCACCACTG
GTCCTCGAGTCAGTGCTCTGTCTGTCGTGCGGGACCTGGGGTTTTTTGGGATCTACAAGGGTGCCAAAGCATGCTTTCTGCGGGACATTC
CTTTCTCGGCCATCTACTTTCCGTGCTATGCTCATGTGAAGGCTTCCTTTGCAAATGAAGATGGGCAGGTTAGCCCAGGAAGCCTGCTCT
TAGCTGGTGCCATAGCTGGTATGCCTGCAGCATCTTTAGTGACCCCTGCTGATGTTATCAAGACGAGATTACAGGTGGCTGCCCGGGCTG
GCCAAACCACTTACAGCGGAGTGATAGACTGCTTTAGAAAGATACTGCGTGAAGAAGGACCAAAAGCTCTGTGGAAGGGAGCTGGTGCTC
GTGTATTTCGATCCTCACCCCAGTTTGGTGTAACTTTGCTGACTTACGAATTGCTACAGCGATGGTTCTACATTGATTTTGGAGGAGTAA
AACCCATGGGATCAGAGCCAGTTCCTAAATCCAGGATCAACCTGCCTGCCCCGAATCCTGATCACGTTGGGGGCTACAAACTGGCAGTTG
CTACATTTGCAGGGATTGAAAACAAATTTGGACTTTACCTACCTCTCTTCAAGCCATCAGTATCTACCTCAAAGGCTATTGGTGGAGGCC
CATAGGAAGATCAGCCCTGGGATAGTGCTGTCTTTTTGTGGGTACTGCAGTAAAGAACATCCCTCCTGGGAATGAAGCAATGCTTCATCC
CTTTTACGTCCATCTCTTGTTTAAATTCAAGTCCAGGCTTTTTTATCATGTGAAATCATTCATTTTCTGGGTGTTTTCTTAACCAGATCA
TTGTGAAATTATTCATAATTATTATTTGGCCCTCTGCCCAGAAACCTTTGTTTGCATCTGAAAATTGATGGGATTTGGTCAACACTAACA

>In-frame_ART3_ENST00000349321_chr4_76997111_+_SLC25A13_ENST00000265631_chr7_95776008_-_1876nt
CTCACTGTCAACAACATCCCATCCTGAAGACTTGCTTACCACAACTGAGAGTGGGGAGTCAGTTTGAGGCCTAGCATCACTTAAACTTCC
TCCAAAGGCACAAAAGCCAGAAGAGAAAAATGAAGACGGGACATTTTGAAATAGTCACCATGCTGCTGGCAACCATGATTCTAGTGGACA
TTTTCCAGGCTGGAGGCTCCCAGGTGATTTTCACAAATCCTTTAGAAATCGTCAAGATCCGTTTGCAAGTGGCAGGAGAAATCACCACTG
GTCCTCGAGTCAGTGCTCTGTCTGTCGTGCGGGACCTGGGGTTTTTTGGGATCTACAAGGGTGCCAAAGCATGCTTTCTGCGGGACATTC
CTTTCTCGGCCATCTACTTTCCGTGCTATGCTCATGTGAAGGCTTCCTTTGCAAATGAAGATGGGCAGGTTAGCCCAGGAAGCCTGCTCT
TAGCTGGTGCCATAGCTGGTATGCCTGCAGCATCTTTAGTGACCCCTGCTGATGTTATCAAGACGAGATTACAGGTGGCTGCCCGGGCTG
GCCAAACCACTTACAGCGGAGTGATAGACTGCTTTAGAAAGATACTGCGTGAAGAAGGACCAAAAGCTCTGTGGAAGGGAGCTGGTGCTC
GTGTATTTCGATCCTCACCCCAGTTTGGTGTAACTTTGCTGACTTACGAATTGCTACAGCGATGGTTCTACATTGATTTTGGAGGAGTAA
AACCCATGGGATCAGAGCCAGTTCCTAAATCCAGGATCAACCTGCCTGCCCCGAATCCTGATCACGTTGGGGGCTACAAACTGGCAGTTG
CTACATTTGCAGGGATTGAAAACAAATTTGGACTTTACCTACCTCTCTTCAAGCCATCAGTATCTACCTCAAAGGCTATTGGTGGAGGCC
CATAGGAAGATCAGCCCTGGGATAGTGCTGTCTTTTTGTGGGTACTGCAGTAAAGAACATCCCTCCTGGGAATGAAGCAATGCTTCATCC
CTTTTACGTCCATCTCTTGTTTAAATTCAAGTCCAGGCTTTTTTATCATGTGAAATCATTCATTTTCTGGGTGTTTTCTTAACCAGATCA
TTGTGAAATTATTCATAATTATTATTTGGCCCTCTGCCCAGAAACCTTTGTTTGCATCTGAAAATTGATGGGATTTGGTCAACACTAACA
TGATTTGGGGAAAGGAGCAAGTCAGAATAGAAATTAGTACTCCCCTCCTTGAACTAGGATTGTAGTCCCAAAGAGGCTACTGTAAGGCAA
TCATGGTGCTCAGAGCAGTGTTTCGTGTGTGTTTTAAACTGGTAGGAAACTAGGTGCATATTTATAAAAATAAAAAACACTGGGAGAAAT
GAAAAAATATATATCAAATATATTCAGCCTGGCTTCAAATTGTAAGCATGCACAAATTCTGTCTCTGGATTATATTATGAAGCTTTTATG
TGAAACATGTTTCTTTGTAATGAAAACCACATTGGAGATGTTTAGTAATCATATTGTTACTGGTACCAAGACTACTAGGGAAATGCCTTT
GTACTTTAGGGAAGTACTTTTGGCATTTTACTGTACAGACAGAAAAAACTGAGATGTAGCCCCTCTCCTGGAAGTGCTAATTTTGAAAAA
CTGCTCATATGATGTACATGTACTGATTACTGCCTATTTTAATAAACACTCTTGAAAAATGCATGTTGCCCTGTTGCTGCCTGCCCTATT
CTCCTCATCTCCCCATCATTGGTACCCACTTGCTTTTAAAATCCACTTTATCTTGAATAATGTAAGACAAATATGTTCTGACATAAGTAT

>In-frame_ART3_ENST00000349321_chr4_76997111_+_SLC25A13_ENST00000416240_chr7_95776008_-_1875nt
CTCACTGTCAACAACATCCCATCCTGAAGACTTGCTTACCACAACTGAGAGTGGGGAGTCAGTTTGAGGCCTAGCATCACTTAAACTTCC
TCCAAAGGCACAAAAGCCAGAAGAGAAAAATGAAGACGGGACATTTTGAAATAGTCACCATGCTGCTGGCAACCATGATTCTAGTGGACA
TTTTCCAGGCTGGAGGCTCCCAGGTGATTTTCACAAATCCTTTAGAAATCGTCAAGATCCGTTTGCAAGTGGCAGGAGAAATCACCACTG
GTCCTCGAGTCAGTGCTCTGTCTGTCGTGCGGGACCTGGGGTTTTTTGGGATCTACAAGGGTGCCAAAGCATGCTTTCTGCGGGACATTC
CTTTCTCGGCCATCTACTTTCCGTGCTATGCTCATGTGAAGGCTTCCTTTGCAAATGAAGATGGGCAGGTTAGCCCAGGAAGCCTGCTCT
TAGCTGGTGCCATAGCTGGTATGCCTGCAGCATCTTTAGTGACCCCTGCTGATGTTATCAAGACGAGATTACAGGTGGCTGCCCGGGCTG
GCCAAACCACTTACAGCGGAGTGATAGACTGCTTTAGAAAGATACTGCGTGAAGAAGGACCAAAAGCTCTGTGGAAGGGAGCTGGTGCTC
GTGTATTTCGATCCTCACCCCAGTTTGGTGTAACTTTGCTGACTTACGAATTGCTACAGCGATGGTTCTACATTGATTTTGGAGGAGTAA
AACCCATGGGATCAGAGCCAGTTCCTAAATCCAGGATCAACCTGCCTGCCCCGAATCCTGATCACGTTGGGGGCTACAAACTGGCAGTTG
CTACATTTGCAGGGATTGAAAACAAATTTGGACTTTACCTACCTCTCTTCAAGCCATCAGTATCTACCTCAAAGGCTATTGGTGGAGGCC
CATAGGAAGATCAGCCCTGGGATAGTGCTGTCTTTTTGTGGGTACTGCAGTAAAGAACATCCCTCCTGGGAATGAAGCAATGCTTCATCC
CTTTTACGTCCATCTCTTGTTTAAATTCAAGTCCAGGCTTTTTTATCATGTGAAATCATTCATTTTCTGGGTGTTTTCTTAACCAGATCA
TTGTGAAATTATTCATAATTATTATTTGGCCCTCTGCCCAGAAACCTTTGTTTGCATCTGAAAATTGATGGGATTTGGTCAACACTAACA
TGATTTGGGGAAAGGAGCAAGTCAGAATAGAAATTAGTACTCCCCTCCTTGAACTAGGATTGTAGTCCCAAAGAGGCTACTGTAAGGCAA
TCATGGTGCTCAGAGCAGTGTTTCGTGTGTGTTTTAAACTGGTAGGAAACTAGGTGCATATTTATAAAAATAAAAAACACTGGGAGAAAT
GAAAAAATATATATCAAATATATTCAGCCTGGCTTCAAATTGTAAGCATGCACAAATTCTGTCTCTGGATTATATTATGAAGCTTTTATG
TGAAACATGTTTCTTTGTAATGAAAACCACATTGGAGATGTTTAGTAATCATATTGTTACTGGTACCAAGACTACTAGGGAAATGCCTTT
GTACTTTAGGGAAGTACTTTTGGCATTTTACTGTACAGACAGAAAAAACTGAGATGTAGCCCCTCTCCTGGAAGTGCTAATTTTGAAAAA
CTGCTCATATGATGTACATGTACTGATTACTGCCTATTTTAATAAACACTCTTGAAAAATGCATGTTGCCCTGTTGCTGCCTGCCCTATT
CTCCTCATCTCCCCATCATTGGTACCCACTTGCTTTTAAAATCCACTTTATCTTGAATAATGTAAGACAAATATGTTCTGACATAAGTAT

>In-frame_ART3_ENST00000349321_chr4_76997111_+_SLC25A13_ENST00000542654_chr7_95776008_-_1196nt
CTCACTGTCAACAACATCCCATCCTGAAGACTTGCTTACCACAACTGAGAGTGGGGAGTCAGTTTGAGGCCTAGCATCACTTAAACTTCC
TCCAAAGGCACAAAAGCCAGAAGAGAAAAATGAAGACGGGACATTTTGAAATAGTCACCATGCTGCTGGCAACCATGATTCTAGTGGACA
TTTTCCAGGCTGGAGGCTCCCAGGTGATTTTCACAAATCCTTTAGAAATCGTCAAGATCCGTTTGCAAGTGGCAGGAGAAATCACCACTG
GTCCTCGAGTCAGTGCTCTGTCTGTCGTGCGGGACCTGGGGTTTTTTGGGATCTACAAGGGTGCCAAAGCATGCTTTCTGCGGGACATTC
CTTTCTCGGCCATCTACTTTCCGTGCTATGCTCATGTGAAGGCTTCCTTTGCAAATGAAGATGGGCAGGTTAGCCCAGGAAGCCTGCTCT
TAGCTGGTGCCATAGCTGGTATGCCTGCAGCATCTTTAGTGACCCCTGCTGATGTTATCAAGACGAGATTACAGGTGGCTGCCCGGGCTG
GCCAAACCACTTACAGCGGAGTGATAGACTGCTTTAGAAAGATACTGCGTGAAGAAGGACCAAAAGCTCTGTGGAAGGGAGCTGGTGCTC
GTGTATTTCGATCCTCACCCCAGTTTGGTGTAACTTTGCTGACTTACGAATTGCTACAGCGATGGTTCTACATTGATTTTGGAGGAGTAA
AACCCATGGGATCAGAGCCAGTTCCTAAATCCAGGATCAACCTGCCTGCCCCGAATCCTGATCACGTTGGGGGCTACAAACTGGCAGTTG
CTACATTTGCAGGGATTGAAAACAAATTTGGACTTTACCTACCTCTCTTCAAGCCATCAGTATCTACCTCAAAGGCTATTGGTGGAGGCC
CATAGGAAGATCAGCCCTGGGATAGTGCTGTCTTTTTGTGGGTACTGCAGTAAAGAACATCCCTCCTGGGAATGAAGCAATGCTTCATCC
CTTTTACGTCCATCTCTTGTTTAAATTCAAGTCCAGGCTTTTTTATCATGTGAAATCATTCATTTTCTGGGTGTTTTCTTAACCAGATCA
TTGTGAAATTATTCATAATTATTATTTGGCCCTCTGCCCAGAAACCTTTGTTTGCATCTGAAAATTGATGGGATTTGGTCAACACTAACA


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FusionGenePPI for ART3_SLC25A13


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
ART3ALCAM, PRKCD, MDN1, ATP12A, PIGO, RAB39B, DDX19B, CHD1L, DYNC2LI1, PAM, NAGLU, ARSK, HSPA12A, GPD1L, ITGA7, MGAT5, CBWD3, POGLUT1, SPG7, PSEN2, MAP2K2, SCAMP2, GALNT7, ITGA8SLC25A13USP50, BRE, BABAM1, SLX1B, UBC, MYC, ICT1, AGO4, SIRT7, MRPL46, ALB, ATF2, GRB2, CLN3, CLN5, ADRB2, FBXO6, PARK2, ASB8, CCDC8, EGFR, AATK, ARAF, IKBKB, ILK, IRAK1, LIMK2, SIK2, PPT1, NTRK1, ELAVL1, IMMT, CRK, XRCC3, NEIL3, SKI, MCM2, NF2, OTUB1, ZNF746, SLC25A12, CYLD, DLST, PDHA1, SOAT1, VDAC1, TRIM25


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for ART3_SLC25A13


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for ART3_SLC25A13


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneSLC25A13C0023893Liver Cirrhosis, Experimental1CTD_human
TgeneSLC25A13C1853942CITRULLINEMIA, TYPE II, NEONATAL-ONSET1CTD_human;ORPHANET;UNIPROT
TgeneSLC25A13C1863844Adult-onset citrullinemia type 21CTD_human;ORPHANET