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Fusion gene ID: 28699 |
FusionGeneSummary for PRKAR1B_GNA12 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PRKAR1B_GNA12 | Fusion gene ID: 28699 | Hgene | Tgene | Gene symbol | PRKAR1B | GNA12 | Gene ID | 5575 | 2768 |
| Gene name | protein kinase cAMP-dependent type I regulatory subunit beta | G protein subunit alpha 12 | |
| Synonyms | PRKAR1 | NNX3|RMP|gep | |
| Cytomap | 7p22.3 | 7p22.3-p22.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | cAMP-dependent protein kinase type I-beta regulatory subunitprotein kinase, cAMP-dependent, regulatory subunit type I betaprotein kinase, cAMP-dependent, regulatory, type I, beta | guanine nucleotide-binding protein subunit alpha-12WUGSC:H_GS165O14.2g alpha-12guanine nucleotide binding protein (G protein) alpha 12 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | P31321 | Q03113 | |
| Ensembl transtripts involved in fusion gene | ENST00000544935, ENST00000537384, ENST00000406797, ENST00000403562, ENST00000360274, ENST00000488474, | ENST00000275364, ENST00000544127, ENST00000491117, ENST00000407904, ENST00000407653, ENST00000396960, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 6 X 5 X 4=120 |
| # samples | 1 | 7 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(7/120*10)=-0.777607578663552 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: PRKAR1B [Title/Abstract] AND GNA12 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | PRKAR1B | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity | 21812984 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | OV | TCGA-24-1847-01A | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000544935 | ENST00000275364 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-intron | ENST00000544935 | ENST00000544127 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000544935 | ENST00000491117 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000544935 | ENST00000407904 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000544935 | ENST00000407653 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000544935 | ENST00000396960 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| Frame-shift | ENST00000537384 | ENST00000275364 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-intron | ENST00000537384 | ENST00000544127 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000537384 | ENST00000491117 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000537384 | ENST00000407904 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000537384 | ENST00000407653 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000537384 | ENST00000396960 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| In-frame | ENST00000406797 | ENST00000275364 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-intron | ENST00000406797 | ENST00000544127 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000406797 | ENST00000491117 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000406797 | ENST00000407904 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000406797 | ENST00000407653 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000406797 | ENST00000396960 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| In-frame | ENST00000403562 | ENST00000275364 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-intron | ENST00000403562 | ENST00000544127 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000403562 | ENST00000491117 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000403562 | ENST00000407904 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000403562 | ENST00000407653 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000403562 | ENST00000396960 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| Frame-shift | ENST00000360274 | ENST00000275364 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-intron | ENST00000360274 | ENST00000544127 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000360274 | ENST00000491117 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000360274 | ENST00000407904 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000360274 | ENST00000407653 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| 5CDS-5UTR | ENST00000360274 | ENST00000396960 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| intron-3CDS | ENST00000488474 | ENST00000275364 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| intron-intron | ENST00000488474 | ENST00000544127 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| intron-5UTR | ENST00000488474 | ENST00000491117 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| intron-5UTR | ENST00000488474 | ENST00000407904 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| intron-5UTR | ENST00000488474 | ENST00000407653 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
| intron-5UTR | ENST00000488474 | ENST00000396960 | PRKAR1B | chr7 | 645830 | - | GNA12 | chr7 | 2773135 | - |
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FusionProtFeatures for PRKAR1B_GNA12 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| PRKAR1B | GNA12 |
| Regulatory subunit of the cAMP-dependent protein kinasesinvolved in cAMP signaling in cells.{ECO:0000269|PubMed:20819953}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | PRKAR1B | chr7:645830 | chr7:2773135 | ENST00000360274 | - | 6 | 11 | 96_100 | 183 | 382 | Motif | Note=Pseudophosphorylation motif |
| Hgene | PRKAR1B | chr7:645830 | chr7:2773135 | ENST00000403562 | - | 6 | 11 | 96_100 | 183 | 382 | Motif | Note=Pseudophosphorylation motif |
| Hgene | PRKAR1B | chr7:645830 | chr7:2773135 | ENST00000406797 | - | 6 | 11 | 96_100 | 183 | 382 | Motif | Note=Pseudophosphorylation motif |
| Hgene | PRKAR1B | chr7:645830 | chr7:2773135 | ENST00000537384 | - | 6 | 11 | 96_100 | 183 | 382 | Motif | Note=Pseudophosphorylation motif |
| Hgene | PRKAR1B | chr7:645830 | chr7:2773135 | ENST00000544935 | - | 6 | 11 | 96_100 | 183 | 382 | Motif | Note=Pseudophosphorylation motif |
| Hgene | PRKAR1B | chr7:645830 | chr7:2773135 | ENST00000360274 | - | 6 | 11 | 2_136 | 183 | 382 | Region | Note=Dimerization and phosphorylation |
| Hgene | PRKAR1B | chr7:645830 | chr7:2773135 | ENST00000403562 | - | 6 | 11 | 2_136 | 183 | 382 | Region | Note=Dimerization and phosphorylation |
| Hgene | PRKAR1B | chr7:645830 | chr7:2773135 | ENST00000406797 | - | 6 | 11 | 2_136 | 183 | 382 | Region | Note=Dimerization and phosphorylation |
| Hgene | PRKAR1B | chr7:645830 | chr7:2773135 | ENST00000537384 | - | 6 | 11 | 2_136 | 183 | 382 | Region | Note=Dimerization and phosphorylation |
| Hgene | PRKAR1B | chr7:645830 | chr7:2773135 | ENST00000544935 | - | 6 | 11 | 2_136 | 183 | 382 | Region | Note=Dimerization and phosphorylation |
| Tgene | >GNA12 | chr7:645830 | chr7:2773135 | ENST00000275364 | - | 1 | 4 | 202_205 | 175 | 382 | Nucleotide binding | GTP |
| Tgene | >GNA12 | chr7:645830 | chr7:2773135 | ENST00000275364 | - | 1 | 4 | 296_299 | 175 | 382 | Nucleotide binding | GTP |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >PRKAR1B | chr7:645830 | chr7:2773135 | ENST00000360274 | - | 6 | 11 | 137_254 | 183 | 382 | Nucleotide binding | Note=cAMP 1 |
| Hgene | >PRKAR1B | chr7:645830 | chr7:2773135 | ENST00000360274 | - | 6 | 11 | 255_381 | 183 | 382 | Nucleotide binding | Note=cAMP 2 |
| Hgene | >PRKAR1B | chr7:645830 | chr7:2773135 | ENST00000403562 | - | 6 | 11 | 137_254 | 183 | 382 | Nucleotide binding | Note=cAMP 1 |
| Hgene | >PRKAR1B | chr7:645830 | chr7:2773135 | ENST00000403562 | - | 6 | 11 | 255_381 | 183 | 382 | Nucleotide binding | Note=cAMP 2 |
| Hgene | >PRKAR1B | chr7:645830 | chr7:2773135 | ENST00000406797 | - | 6 | 11 | 137_254 | 183 | 382 | Nucleotide binding | Note=cAMP 1 |
| Hgene | >PRKAR1B | chr7:645830 | chr7:2773135 | ENST00000406797 | - | 6 | 11 | 255_381 | 183 | 382 | Nucleotide binding | Note=cAMP 2 |
| Hgene | >PRKAR1B | chr7:645830 | chr7:2773135 | ENST00000537384 | - | 6 | 11 | 137_254 | 183 | 382 | Nucleotide binding | Note=cAMP 1 |
| Hgene | >PRKAR1B | chr7:645830 | chr7:2773135 | ENST00000537384 | - | 6 | 11 | 255_381 | 183 | 382 | Nucleotide binding | Note=cAMP 2 |
| Hgene | >PRKAR1B | chr7:645830 | chr7:2773135 | ENST00000544935 | - | 6 | 11 | 137_254 | 183 | 382 | Nucleotide binding | Note=cAMP 1 |
| Hgene | >PRKAR1B | chr7:645830 | chr7:2773135 | ENST00000544935 | - | 6 | 11 | 255_381 | 183 | 382 | Nucleotide binding | Note=cAMP 2 |
| Tgene | GNA12 | chr7:645830 | chr7:2773135 | ENST00000275364 | - | 1 | 4 | 67_72 | 175 | 382 | Nucleotide binding | GTP |
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FusionGeneSequence for PRKAR1B_GNA12 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_PRKAR1B_ENST00000544935_chr7_645830_-_GNA12_ENST00000275364_chr7_2773135_-_390aa MASPPACPSEEDESLKGCELYVQLHGIQQVLKDCIVHLCISKPERPMKFLREHFEKLEKEENRQILARQKSNSQSDSHDEEVSPTPPNPV VKARRRRGGVSAEVYTEEDAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETVIQQGNEGDNFYVVDQG EVDGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLM EDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQRYLVQCFDRKRRNRSKPLFHHFTT >In-frame_PRKAR1B_ENST00000406797_chr7_645830_-_GNA12_ENST00000275364_chr7_2773135_-_390aa MASPPACPSEEDESLKGCELYVQLHGIQQVLKDCIVHLCISKPERPMKFLREHFEKLEKEENRQILARQKSNSQSDSHDEEVSPTPPNPV VKARRRRGGVSAEVYTEEDAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETVIQQGNEGDNFYVVDQG EVDGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLM EDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQRYLVQCFDRKRRNRSKPLFHHFTT >In-frame_PRKAR1B_ENST00000403562_chr7_645830_-_GNA12_ENST00000275364_chr7_2773135_-_390aa MASPPACPSEEDESLKGCELYVQLHGIQQVLKDCIVHLCISKPERPMKFLREHFEKLEKEENRQILARQKSNSQSDSHDEEVSPTPPNPV VKARRRRGGVSAEVYTEEDAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETVIQQGNEGDNFYVVDQG EVDGESVKYFLDNLDRIGQLNYFPSKQDILLARKATKGIVEHDFVIKKIPFKMVDVGGQRSQRQKWFQCFDGITSILFMVSSSEYDQVLM EDRRTNRLVESMNIFETIVNNKLFFNVSIILFLNKMDLLVEKVKTVSIKKHFPDFRGDPHRLEDVQRYLVQCFDRKRRNRSKPLFHHFTT |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_PRKAR1B_ENST00000544935_chr7_645830_-_GNA12_ENST00000275364_chr7_2773135_-_1170nt ATGGCCTCCCCGCCCGCCTGCCCCTCGGAGGAGGACGAGAGCCTGAAGGGCTGTGAGCTGTACGTGCAGCTGCACGGGATCCAGCAGGTC CTCAAAGACTGTATCGTCCACCTCTGCATCTCCAAGCCCGAACGCCCCATGAAGTTCCTCCGGGAGCACTTCGAGAAGCTGGAGAAGGAA GAAAACAGGCAGATTTTGGCGCGGCAAAAGTCAAACTCACAGTCGGACTCCCATGATGAGGAGGTGTCGCCCACCCCCCCGAACCCTGTG GTGAAGGCCCGCCGCCGGCGAGGAGGCGTGAGTGCCGAGGTGTACACCGAGGAGGACGCCGTGTCCTACGTCAGGAAGGTGATTCCCAAG GACTACAAAACCATGACTGCGCTGGCCAAGGCCATCTCCAAGAACGTGCTCTTCGCTCACCTGGATGACAACGAGAGGAGTGACATATTC GATGCCATGTTCCCTGTCACTCACATCGCTGGGGAGACTGTTATACAGCAAGGGAATGAAGGAGACAACTTCTATGTCGTTGATCAAGGG GAAGTGGATGGGGAGTCGGTGAAGTACTTCCTGGACAACTTGGACCGGATCGGCCAGCTGAATTACTTTCCTAGTAAGCAAGATATCCTG CTGGCTAGGAAAGCCACCAAGGGAATTGTGGAGCATGACTTCGTTATTAAGAAGATCCCCTTTAAGATGGTGGATGTGGGCGGCCAGCGG TCCCAGCGCCAGAAGTGGTTCCAGTGCTTCGACGGGATCACGTCCATCCTGTTCATGGTCTCCTCCAGCGAGTACGACCAGGTCCTCATG GAGGACAGGCGCACCAACCGGCTGGTGGAGTCCATGAACATCTTCGAGACCATCGTCAACAACAAGCTCTTCTTCAACGTCTCCATCATT CTCTTCCTCAACAAGATGGACCTCCTGGTGGAGAAGGTGAAGACCGTGAGCATCAAGAAGCACTTCCCGGACTTCAGGGGCGACCCGCAC AGGCTGGAGGACGTCCAGCGCTACCTGGTCCAGTGCTTCGACAGGAAGAGACGGAACCGCAGCAAGCCACTCTTCCACCACTTCACCACC GCCATCGACACCGAGAACGTCCGCTTCGTGTTCCATGCTGTGAAAGACACCATCCTGCAGGAGAACCTGAAGGACATCATGCTGCAGTGA >In-frame_PRKAR1B_ENST00000406797_chr7_645830_-_GNA12_ENST00000275364_chr7_2773135_-_1170nt ATGGCCTCCCCGCCCGCCTGCCCCTCGGAGGAGGACGAGAGCCTGAAGGGCTGTGAGCTGTACGTGCAGCTGCACGGGATCCAGCAGGTC CTCAAAGACTGTATCGTCCACCTCTGCATCTCCAAGCCCGAACGCCCCATGAAGTTCCTCCGGGAGCACTTCGAGAAGCTGGAGAAGGAA GAAAACAGGCAGATTTTGGCGCGGCAAAAGTCAAACTCACAGTCGGACTCCCATGATGAGGAGGTGTCGCCCACCCCCCCGAACCCTGTG GTGAAGGCCCGCCGCCGGCGAGGAGGCGTGAGTGCCGAGGTGTACACCGAGGAGGACGCCGTGTCCTACGTCAGGAAGGTGATTCCCAAG GACTACAAAACCATGACTGCGCTGGCCAAGGCCATCTCCAAGAACGTGCTCTTCGCTCACCTGGATGACAACGAGAGGAGTGACATATTC GATGCCATGTTCCCTGTCACTCACATCGCTGGGGAGACTGTTATACAGCAAGGGAATGAAGGAGACAACTTCTATGTCGTTGATCAAGGG GAAGTGGATGGGGAGTCGGTGAAGTACTTCCTGGACAACTTGGACCGGATCGGCCAGCTGAATTACTTTCCTAGTAAGCAAGATATCCTG CTGGCTAGGAAAGCCACCAAGGGAATTGTGGAGCATGACTTCGTTATTAAGAAGATCCCCTTTAAGATGGTGGATGTGGGCGGCCAGCGG TCCCAGCGCCAGAAGTGGTTCCAGTGCTTCGACGGGATCACGTCCATCCTGTTCATGGTCTCCTCCAGCGAGTACGACCAGGTCCTCATG GAGGACAGGCGCACCAACCGGCTGGTGGAGTCCATGAACATCTTCGAGACCATCGTCAACAACAAGCTCTTCTTCAACGTCTCCATCATT CTCTTCCTCAACAAGATGGACCTCCTGGTGGAGAAGGTGAAGACCGTGAGCATCAAGAAGCACTTCCCGGACTTCAGGGGCGACCCGCAC AGGCTGGAGGACGTCCAGCGCTACCTGGTCCAGTGCTTCGACAGGAAGAGACGGAACCGCAGCAAGCCACTCTTCCACCACTTCACCACC GCCATCGACACCGAGAACGTCCGCTTCGTGTTCCATGCTGTGAAAGACACCATCCTGCAGGAGAACCTGAAGGACATCATGCTGCAGTGA >In-frame_PRKAR1B_ENST00000403562_chr7_645830_-_GNA12_ENST00000275364_chr7_2773135_-_1170nt ATGGCCTCCCCGCCCGCCTGCCCCTCGGAGGAGGACGAGAGCCTGAAGGGCTGTGAGCTGTACGTGCAGCTGCACGGGATCCAGCAGGTC CTCAAAGACTGTATCGTCCACCTCTGCATCTCCAAGCCCGAACGCCCCATGAAGTTCCTCCGGGAGCACTTCGAGAAGCTGGAGAAGGAA GAAAACAGGCAGATTTTGGCGCGGCAAAAGTCAAACTCACAGTCGGACTCCCATGATGAGGAGGTGTCGCCCACCCCCCCGAACCCTGTG GTGAAGGCCCGCCGCCGGCGAGGAGGCGTGAGTGCCGAGGTGTACACCGAGGAGGACGCCGTGTCCTACGTCAGGAAGGTGATTCCCAAG GACTACAAAACCATGACTGCGCTGGCCAAGGCCATCTCCAAGAACGTGCTCTTCGCTCACCTGGATGACAACGAGAGGAGTGACATATTC GATGCCATGTTCCCTGTCACTCACATCGCTGGGGAGACTGTTATACAGCAAGGGAATGAAGGAGACAACTTCTATGTCGTTGATCAAGGG GAAGTGGATGGGGAGTCGGTGAAGTACTTCCTGGACAACTTGGACCGGATCGGCCAGCTGAATTACTTTCCTAGTAAGCAAGATATCCTG CTGGCTAGGAAAGCCACCAAGGGAATTGTGGAGCATGACTTCGTTATTAAGAAGATCCCCTTTAAGATGGTGGATGTGGGCGGCCAGCGG TCCCAGCGCCAGAAGTGGTTCCAGTGCTTCGACGGGATCACGTCCATCCTGTTCATGGTCTCCTCCAGCGAGTACGACCAGGTCCTCATG GAGGACAGGCGCACCAACCGGCTGGTGGAGTCCATGAACATCTTCGAGACCATCGTCAACAACAAGCTCTTCTTCAACGTCTCCATCATT CTCTTCCTCAACAAGATGGACCTCCTGGTGGAGAAGGTGAAGACCGTGAGCATCAAGAAGCACTTCCCGGACTTCAGGGGCGACCCGCAC AGGCTGGAGGACGTCCAGCGCTACCTGGTCCAGTGCTTCGACAGGAAGAGACGGAACCGCAGCAAGCCACTCTTCCACCACTTCACCACC GCCATCGACACCGAGAACGTCCGCTTCGTGTTCCATGCTGTGAAAGACACCATCCTGCAGGAGAACCTGAAGGACATCATGCTGCAGTGA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_PRKAR1B_ENST00000544935_chr7_645830_-_GNA12_ENST00000275364_chr7_2773135_-_4354nt CTCTGGCCGCTAAGGCAGAGTGAGACCCCAGGGAACGGGCGTGCTTGCTGGGTACCGGGTGTCCTGCAGAGGCAGGGATGTGATCCCCTA GGTGAAGGAAGCAGCCACCCTCGCCATGGCCTCCCCGCCCGCCTGCCCCTCGGAGGAGGACGAGAGCCTGAAGGGCTGTGAGCTGTACGT GCAGCTGCACGGGATCCAGCAGGTCCTCAAAGACTGTATCGTCCACCTCTGCATCTCCAAGCCCGAACGCCCCATGAAGTTCCTCCGGGA GCACTTCGAGAAGCTGGAGAAGGAAGAAAACAGGCAGATTTTGGCGCGGCAAAAGTCAAACTCACAGTCGGACTCCCATGATGAGGAGGT GTCGCCCACCCCCCCGAACCCTGTGGTGAAGGCCCGCCGCCGGCGAGGAGGCGTGAGTGCCGAGGTGTACACCGAGGAGGACGCCGTGTC CTACGTCAGGAAGGTGATTCCCAAGGACTACAAAACCATGACTGCGCTGGCCAAGGCCATCTCCAAGAACGTGCTCTTCGCTCACCTGGA TGACAACGAGAGGAGTGACATATTCGATGCCATGTTCCCTGTCACTCACATCGCTGGGGAGACTGTTATACAGCAAGGGAATGAAGGAGA CAACTTCTATGTCGTTGATCAAGGGGAAGTGGATGGGGAGTCGGTGAAGTACTTCCTGGACAACTTGGACCGGATCGGCCAGCTGAATTA CTTTCCTAGTAAGCAAGATATCCTGCTGGCTAGGAAAGCCACCAAGGGAATTGTGGAGCATGACTTCGTTATTAAGAAGATCCCCTTTAA GATGGTGGATGTGGGCGGCCAGCGGTCCCAGCGCCAGAAGTGGTTCCAGTGCTTCGACGGGATCACGTCCATCCTGTTCATGGTCTCCTC CAGCGAGTACGACCAGGTCCTCATGGAGGACAGGCGCACCAACCGGCTGGTGGAGTCCATGAACATCTTCGAGACCATCGTCAACAACAA GCTCTTCTTCAACGTCTCCATCATTCTCTTCCTCAACAAGATGGACCTCCTGGTGGAGAAGGTGAAGACCGTGAGCATCAAGAAGCACTT CCCGGACTTCAGGGGCGACCCGCACAGGCTGGAGGACGTCCAGCGCTACCTGGTCCAGTGCTTCGACAGGAAGAGACGGAACCGCAGCAA GCCACTCTTCCACCACTTCACCACCGCCATCGACACCGAGAACGTCCGCTTCGTGTTCCATGCTGTGAAAGACACCATCCTGCAGGAGAA CCTGAAGGACATCATGCTGCAGTGAGCGAGGAAGCCCCGGGGTTTGTCGTCGTTGAGCAGCCCCCACGGCTGTCGGTCAGACTCTTGGGT GTGTGTTGTCTGTGTGGTCCTTGAGTGGGTTTCTCGGATCCGTGCCCTGGAATACCTGGCTCAGGAATGCTGTCAGACCAGCCAGCCAGC GAGCTCTAGGCAAAAGGACATGGAAACTGTCACGTTAGCTACTGAATCCTGGGGGCGAGTGAAACTACTGAAAATCCGAGTGATGATGTT GTGAATACGGAACACCTAATCACACAGCTTGCTTTGCTTTTACAGAAACGTTCCTCTTTTTCTGACGCAGTTTAATTGAGGACCGTGTTG TGTGTGTATGTGTGTACACACGCTCTGTCTTTAATGACAGAAACACAAAAACCAGCTGGCCTTGCAGACGGCTTTTCTAACTCACAAGTC TTCCCTGAGACAGACTAACCTGAAAGCTTTGCCTAACAGTAGCTTGTAGAGATCCAGTGCACGCCGATGCTGCTAAACTCAGTGCCTGAG CCCGGCCCTGCAGCCCCAGCCGCAGTGTCTGAAGGCCACCTCCCAAAGGGAGCACGTTGCCTTTTCAAACTCCCGTGCCGATTTCCTAAG AGCCCCTAGTCCAAGCCTCTCAGATGAAGCTGAGGAGCCGTGCCTAGGATCCCTTCCCAGCTCTGAGGACGGGCTGCAGAGCTCTGCAGG TGTGGATTCACCTTACGCCCCTACAGCAGGCTCAGCCCTTCCCACCCTGCCCCATGCCCAGCAGCACAACACGGAGTGAGACAGGATGCC CACGGTGACTGCCGCTCCGTCCGTGCACACACAGCGGTGCTCTTCTCCCCTTAGCCACCCACTGCCCAACCCAACGGCAAAGACACAGAA ACCAGGTCCCCTTGCAGACGGCTCTCCCATCTTCCTGCAAGTCATCTGCTCACACACAGTTGGCAGCACATAGCGTTTCCTTCTTTCAGA AACATTCCTCTTCTGGGGCTTCAGAAAGCTGGCAAGGCCACTAGCAGAGCTTTTGTTAATGCCCCAGCTGCTTGGCGAGCTAACAGCTGA CCTTTCGGGAAGCCCACAGACGCTGGAGGAATCTTGAGTTTCTCCAAACTGCCGCTCCACCAGTGCCTTTGGACAGCCGTGCCTGTTCGC CGCTCTCCCTAAGTCTGATTCTCATCGAGGCCCCTCGCTTCTATGACTGTGCTTGCAGAAGAGTAAACACTCTCGGATGCCGCTGTCCTG GGGGAGCCCGCGGGAGCCTGTGAATGTTGATACGAGCTGGCCAGTCCTGGGCCCAGCTCACTTGTCCAGCTACCTGCCAGGTGGCTTTCA CTGTGTTTAAAATACATTGCATTCCAAGCTGGTCCCCTCTGTGTATCACTCTACTGAGAAATCCTGCCTAGTGTGTTTTGGGATGTGTCC TAGCATTTACAAGAAAATGAAAAGCGTCCTCTTAATTGGCACCCGAATGTTGCTGTGGCTCAGTCACATATCCCAGGGCCCTCGTCCCGA GGCCGTGCTGCCCCGAGCCCCGAGCCCCTCTGCAGCTCACCCTTGGCTTGTTTTCCGCAAACCCGGTAAACGCAAGCCCTTGGGGCAGAT GCAGAAGCAGAAGAGGGAGGGGAAACCTGCCTCTGGGTCACCCTGTTAGCACAGCGTTCTCATCGGGAGACAGCATGGAACTCTCTCTCG CAGTGCTCGAGGCTGTGTGTCAGTGTTTGCTGGGCTTGTGGCTCCTTTTTTGGCTGGATAAAGAAGTCGCTGTTTTTGTACTGCTTCTGT GGCTCTTCACAGACCTCACGGATGTGACCGGAGATGAGTGCCGATGACCACGTTTTAAAGGAGAAAGAGAGCTCCTGGTGGGGCCCTCGG GGTGGTCTCAGGTCCCATTTGCAGTCTGCAACAGTGACGCGCAGCCCGGTCCGGAGCGTGGTGAGCTTTGTTTGCCTTCTGGGTCAGCTT TCGCTGTGTCTCCTGTGTGTGTTAGAATCCAGAGCCCAGAGGAAGTGCAAGCGGGTCCTCCGCCAACGGGGAGAGCCTCTTCGCGGCGCT GTTGGCGACAGCAGCGCTGTGATTCGCGTAGCAGGGGAGTTGTTTGAAACACCTTCCTGAGTAGTCCGGCCTTGTCAATGAGTGCTTGTT TTCCTTTAAACAGTCTGACATATTTACTCGTCACTTTCAAACCAGAAGCATGAGAGGAAGGAGATATTGTGGGGTCCGTTTAACTCGATA GAAAGCGCAGGGGGATGGCCCCCGGCGCGGGCTCTTGACCCGCTCAGCGCTGACCCCACCGCCCTGGCCGAGGCACTTGGCCTTGCTGAG CTGGACTTCCTCCTCCTCCTCCTCATGACCGGGGTGAATTAGAACGTTTTTAAAGACACCCCCTTCCAAATTCTGTAACACATTGTAATT GGAGAAGAAGGAAACTCTGCAAGGCTAAACTGTCATTCACAACTTGGCTACACATAGACTCTAGTCAGTTTTGTCTCCAGAACCTTAGGC TTTTGTATTTTTTAATTTTAATTTCACTGTTAATCCTTATTGTCTTTTTTATTAAGATGTTGGAAAAGCAGGAGGTAGTTGTGCCTCAAT TATTGCAAAAATGTAACAATAAAGTTCCTCAAAATAAGATCTGTTCCTCATAGCTATACTGTGTACACATAAGACGCATATAGGGTTTTA CTGAAATCTATTTTTAACTCTTATGTTCGTAGAGAAATTGTTTCAAGGATTTTGAGTCATAGGTCTGTAATTTATAGAGATCTCTAGAAT TCTTATTGTAATTTTCCTACTTCTTTGATAAAAGAAAAATAAGTCAGATTGTTAACTCCAAGATTGAAAAAAAAAACTCTTGAAAGAAGA TTATTAGTTGTAACTAATTTAGGGGTTCTGGGCACAGACATCTAACCTGGTATTGTAAGGCAGAGGCTCCCATTGGAATGGTAGTGGTCC GGGTCAGTTGTTCATGGTGTAAGCTTTGCACAGTGTATTAACATTGGGAGGGTCTGGCTTGAAAATTTGGCCACCCTCAGCCTCTGAATG >In-frame_PRKAR1B_ENST00000406797_chr7_645830_-_GNA12_ENST00000275364_chr7_2773135_-_4414nt AGTTTCTGCCGCCGCCACCCTGGCAGGATGGGGCAACGGTGTGCGGTAGGAGGATGAGGTTGATTCCCTTTCCTGCAGGGCTGGGCTTGT GGGTTAGGACCGTCACCAAGAGGCTCCTCCTAGGCCTCCGTGACCTCTGGATCCCCAAGAAAGGAAGGAAGCAGCCACCCTCGCCATGGC CTCCCCGCCCGCCTGCCCCTCGGAGGAGGACGAGAGCCTGAAGGGCTGTGAGCTGTACGTGCAGCTGCACGGGATCCAGCAGGTCCTCAA AGACTGTATCGTCCACCTCTGCATCTCCAAGCCCGAACGCCCCATGAAGTTCCTCCGGGAGCACTTCGAGAAGCTGGAGAAGGAAGAAAA CAGGCAGATTTTGGCGCGGCAAAAGTCAAACTCACAGTCGGACTCCCATGATGAGGAGGTGTCGCCCACCCCCCCGAACCCTGTGGTGAA GGCCCGCCGCCGGCGAGGAGGCGTGAGTGCCGAGGTGTACACCGAGGAGGACGCCGTGTCCTACGTCAGGAAGGTGATTCCCAAGGACTA CAAAACCATGACTGCGCTGGCCAAGGCCATCTCCAAGAACGTGCTCTTCGCTCACCTGGATGACAACGAGAGGAGTGACATATTCGATGC CATGTTCCCTGTCACTCACATCGCTGGGGAGACTGTTATACAGCAAGGGAATGAAGGAGACAACTTCTATGTCGTTGATCAAGGGGAAGT GGATGGGGAGTCGGTGAAGTACTTCCTGGACAACTTGGACCGGATCGGCCAGCTGAATTACTTTCCTAGTAAGCAAGATATCCTGCTGGC TAGGAAAGCCACCAAGGGAATTGTGGAGCATGACTTCGTTATTAAGAAGATCCCCTTTAAGATGGTGGATGTGGGCGGCCAGCGGTCCCA GCGCCAGAAGTGGTTCCAGTGCTTCGACGGGATCACGTCCATCCTGTTCATGGTCTCCTCCAGCGAGTACGACCAGGTCCTCATGGAGGA CAGGCGCACCAACCGGCTGGTGGAGTCCATGAACATCTTCGAGACCATCGTCAACAACAAGCTCTTCTTCAACGTCTCCATCATTCTCTT CCTCAACAAGATGGACCTCCTGGTGGAGAAGGTGAAGACCGTGAGCATCAAGAAGCACTTCCCGGACTTCAGGGGCGACCCGCACAGGCT GGAGGACGTCCAGCGCTACCTGGTCCAGTGCTTCGACAGGAAGAGACGGAACCGCAGCAAGCCACTCTTCCACCACTTCACCACCGCCAT CGACACCGAGAACGTCCGCTTCGTGTTCCATGCTGTGAAAGACACCATCCTGCAGGAGAACCTGAAGGACATCATGCTGCAGTGAGCGAG GAAGCCCCGGGGTTTGTCGTCGTTGAGCAGCCCCCACGGCTGTCGGTCAGACTCTTGGGTGTGTGTTGTCTGTGTGGTCCTTGAGTGGGT TTCTCGGATCCGTGCCCTGGAATACCTGGCTCAGGAATGCTGTCAGACCAGCCAGCCAGCGAGCTCTAGGCAAAAGGACATGGAAACTGT CACGTTAGCTACTGAATCCTGGGGGCGAGTGAAACTACTGAAAATCCGAGTGATGATGTTGTGAATACGGAACACCTAATCACACAGCTT GCTTTGCTTTTACAGAAACGTTCCTCTTTTTCTGACGCAGTTTAATTGAGGACCGTGTTGTGTGTGTATGTGTGTACACACGCTCTGTCT TTAATGACAGAAACACAAAAACCAGCTGGCCTTGCAGACGGCTTTTCTAACTCACAAGTCTTCCCTGAGACAGACTAACCTGAAAGCTTT GCCTAACAGTAGCTTGTAGAGATCCAGTGCACGCCGATGCTGCTAAACTCAGTGCCTGAGCCCGGCCCTGCAGCCCCAGCCGCAGTGTCT GAAGGCCACCTCCCAAAGGGAGCACGTTGCCTTTTCAAACTCCCGTGCCGATTTCCTAAGAGCCCCTAGTCCAAGCCTCTCAGATGAAGC TGAGGAGCCGTGCCTAGGATCCCTTCCCAGCTCTGAGGACGGGCTGCAGAGCTCTGCAGGTGTGGATTCACCTTACGCCCCTACAGCAGG CTCAGCCCTTCCCACCCTGCCCCATGCCCAGCAGCACAACACGGAGTGAGACAGGATGCCCACGGTGACTGCCGCTCCGTCCGTGCACAC ACAGCGGTGCTCTTCTCCCCTTAGCCACCCACTGCCCAACCCAACGGCAAAGACACAGAAACCAGGTCCCCTTGCAGACGGCTCTCCCAT CTTCCTGCAAGTCATCTGCTCACACACAGTTGGCAGCACATAGCGTTTCCTTCTTTCAGAAACATTCCTCTTCTGGGGCTTCAGAAAGCT GGCAAGGCCACTAGCAGAGCTTTTGTTAATGCCCCAGCTGCTTGGCGAGCTAACAGCTGACCTTTCGGGAAGCCCACAGACGCTGGAGGA ATCTTGAGTTTCTCCAAACTGCCGCTCCACCAGTGCCTTTGGACAGCCGTGCCTGTTCGCCGCTCTCCCTAAGTCTGATTCTCATCGAGG CCCCTCGCTTCTATGACTGTGCTTGCAGAAGAGTAAACACTCTCGGATGCCGCTGTCCTGGGGGAGCCCGCGGGAGCCTGTGAATGTTGA TACGAGCTGGCCAGTCCTGGGCCCAGCTCACTTGTCCAGCTACCTGCCAGGTGGCTTTCACTGTGTTTAAAATACATTGCATTCCAAGCT GGTCCCCTCTGTGTATCACTCTACTGAGAAATCCTGCCTAGTGTGTTTTGGGATGTGTCCTAGCATTTACAAGAAAATGAAAAGCGTCCT CTTAATTGGCACCCGAATGTTGCTGTGGCTCAGTCACATATCCCAGGGCCCTCGTCCCGAGGCCGTGCTGCCCCGAGCCCCGAGCCCCTC TGCAGCTCACCCTTGGCTTGTTTTCCGCAAACCCGGTAAACGCAAGCCCTTGGGGCAGATGCAGAAGCAGAAGAGGGAGGGGAAACCTGC CTCTGGGTCACCCTGTTAGCACAGCGTTCTCATCGGGAGACAGCATGGAACTCTCTCTCGCAGTGCTCGAGGCTGTGTGTCAGTGTTTGC TGGGCTTGTGGCTCCTTTTTTGGCTGGATAAAGAAGTCGCTGTTTTTGTACTGCTTCTGTGGCTCTTCACAGACCTCACGGATGTGACCG GAGATGAGTGCCGATGACCACGTTTTAAAGGAGAAAGAGAGCTCCTGGTGGGGCCCTCGGGGTGGTCTCAGGTCCCATTTGCAGTCTGCA ACAGTGACGCGCAGCCCGGTCCGGAGCGTGGTGAGCTTTGTTTGCCTTCTGGGTCAGCTTTCGCTGTGTCTCCTGTGTGTGTTAGAATCC AGAGCCCAGAGGAAGTGCAAGCGGGTCCTCCGCCAACGGGGAGAGCCTCTTCGCGGCGCTGTTGGCGACAGCAGCGCTGTGATTCGCGTA GCAGGGGAGTTGTTTGAAACACCTTCCTGAGTAGTCCGGCCTTGTCAATGAGTGCTTGTTTTCCTTTAAACAGTCTGACATATTTACTCG TCACTTTCAAACCAGAAGCATGAGAGGAAGGAGATATTGTGGGGTCCGTTTAACTCGATAGAAAGCGCAGGGGGATGGCCCCCGGCGCGG GCTCTTGACCCGCTCAGCGCTGACCCCACCGCCCTGGCCGAGGCACTTGGCCTTGCTGAGCTGGACTTCCTCCTCCTCCTCCTCATGACC GGGGTGAATTAGAACGTTTTTAAAGACACCCCCTTCCAAATTCTGTAACACATTGTAATTGGAGAAGAAGGAAACTCTGCAAGGCTAAAC TGTCATTCACAACTTGGCTACACATAGACTCTAGTCAGTTTTGTCTCCAGAACCTTAGGCTTTTGTATTTTTTAATTTTAATTTCACTGT TAATCCTTATTGTCTTTTTTATTAAGATGTTGGAAAAGCAGGAGGTAGTTGTGCCTCAATTATTGCAAAAATGTAACAATAAAGTTCCTC AAAATAAGATCTGTTCCTCATAGCTATACTGTGTACACATAAGACGCATATAGGGTTTTACTGAAATCTATTTTTAACTCTTATGTTCGT AGAGAAATTGTTTCAAGGATTTTGAGTCATAGGTCTGTAATTTATAGAGATCTCTAGAATTCTTATTGTAATTTTCCTACTTCTTTGATA AAAGAAAAATAAGTCAGATTGTTAACTCCAAGATTGAAAAAAAAAACTCTTGAAAGAAGATTATTAGTTGTAACTAATTTAGGGGTTCTG GGCACAGACATCTAACCTGGTATTGTAAGGCAGAGGCTCCCATTGGAATGGTAGTGGTCCGGGTCAGTTGTTCATGGTGTAAGCTTTGCA CAGTGTATTAACATTGGGAGGGTCTGGCTTGAAAATTTGGCCACCCTCAGCCTCTGAATGTTTATTAAAATAAATTTAGTCTTTCTTTGC >In-frame_PRKAR1B_ENST00000403562_chr7_645830_-_GNA12_ENST00000275364_chr7_2773135_-_4322nt GTGAGGGCCAAGCAGGAACAGGGGTCACGGGGCAAGGAGCACGTGGCAGCGCAGGAAACAGGAAGGAAGCAGCCACCCTCGCCATGGCCT CCCCGCCCGCCTGCCCCTCGGAGGAGGACGAGAGCCTGAAGGGCTGTGAGCTGTACGTGCAGCTGCACGGGATCCAGCAGGTCCTCAAAG ACTGTATCGTCCACCTCTGCATCTCCAAGCCCGAACGCCCCATGAAGTTCCTCCGGGAGCACTTCGAGAAGCTGGAGAAGGAAGAAAACA GGCAGATTTTGGCGCGGCAAAAGTCAAACTCACAGTCGGACTCCCATGATGAGGAGGTGTCGCCCACCCCCCCGAACCCTGTGGTGAAGG CCCGCCGCCGGCGAGGAGGCGTGAGTGCCGAGGTGTACACCGAGGAGGACGCCGTGTCCTACGTCAGGAAGGTGATTCCCAAGGACTACA AAACCATGACTGCGCTGGCCAAGGCCATCTCCAAGAACGTGCTCTTCGCTCACCTGGATGACAACGAGAGGAGTGACATATTCGATGCCA TGTTCCCTGTCACTCACATCGCTGGGGAGACTGTTATACAGCAAGGGAATGAAGGAGACAACTTCTATGTCGTTGATCAAGGGGAAGTGG ATGGGGAGTCGGTGAAGTACTTCCTGGACAACTTGGACCGGATCGGCCAGCTGAATTACTTTCCTAGTAAGCAAGATATCCTGCTGGCTA GGAAAGCCACCAAGGGAATTGTGGAGCATGACTTCGTTATTAAGAAGATCCCCTTTAAGATGGTGGATGTGGGCGGCCAGCGGTCCCAGC GCCAGAAGTGGTTCCAGTGCTTCGACGGGATCACGTCCATCCTGTTCATGGTCTCCTCCAGCGAGTACGACCAGGTCCTCATGGAGGACA GGCGCACCAACCGGCTGGTGGAGTCCATGAACATCTTCGAGACCATCGTCAACAACAAGCTCTTCTTCAACGTCTCCATCATTCTCTTCC TCAACAAGATGGACCTCCTGGTGGAGAAGGTGAAGACCGTGAGCATCAAGAAGCACTTCCCGGACTTCAGGGGCGACCCGCACAGGCTGG AGGACGTCCAGCGCTACCTGGTCCAGTGCTTCGACAGGAAGAGACGGAACCGCAGCAAGCCACTCTTCCACCACTTCACCACCGCCATCG ACACCGAGAACGTCCGCTTCGTGTTCCATGCTGTGAAAGACACCATCCTGCAGGAGAACCTGAAGGACATCATGCTGCAGTGAGCGAGGA AGCCCCGGGGTTTGTCGTCGTTGAGCAGCCCCCACGGCTGTCGGTCAGACTCTTGGGTGTGTGTTGTCTGTGTGGTCCTTGAGTGGGTTT CTCGGATCCGTGCCCTGGAATACCTGGCTCAGGAATGCTGTCAGACCAGCCAGCCAGCGAGCTCTAGGCAAAAGGACATGGAAACTGTCA CGTTAGCTACTGAATCCTGGGGGCGAGTGAAACTACTGAAAATCCGAGTGATGATGTTGTGAATACGGAACACCTAATCACACAGCTTGC TTTGCTTTTACAGAAACGTTCCTCTTTTTCTGACGCAGTTTAATTGAGGACCGTGTTGTGTGTGTATGTGTGTACACACGCTCTGTCTTT AATGACAGAAACACAAAAACCAGCTGGCCTTGCAGACGGCTTTTCTAACTCACAAGTCTTCCCTGAGACAGACTAACCTGAAAGCTTTGC CTAACAGTAGCTTGTAGAGATCCAGTGCACGCCGATGCTGCTAAACTCAGTGCCTGAGCCCGGCCCTGCAGCCCCAGCCGCAGTGTCTGA AGGCCACCTCCCAAAGGGAGCACGTTGCCTTTTCAAACTCCCGTGCCGATTTCCTAAGAGCCCCTAGTCCAAGCCTCTCAGATGAAGCTG AGGAGCCGTGCCTAGGATCCCTTCCCAGCTCTGAGGACGGGCTGCAGAGCTCTGCAGGTGTGGATTCACCTTACGCCCCTACAGCAGGCT CAGCCCTTCCCACCCTGCCCCATGCCCAGCAGCACAACACGGAGTGAGACAGGATGCCCACGGTGACTGCCGCTCCGTCCGTGCACACAC AGCGGTGCTCTTCTCCCCTTAGCCACCCACTGCCCAACCCAACGGCAAAGACACAGAAACCAGGTCCCCTTGCAGACGGCTCTCCCATCT TCCTGCAAGTCATCTGCTCACACACAGTTGGCAGCACATAGCGTTTCCTTCTTTCAGAAACATTCCTCTTCTGGGGCTTCAGAAAGCTGG CAAGGCCACTAGCAGAGCTTTTGTTAATGCCCCAGCTGCTTGGCGAGCTAACAGCTGACCTTTCGGGAAGCCCACAGACGCTGGAGGAAT CTTGAGTTTCTCCAAACTGCCGCTCCACCAGTGCCTTTGGACAGCCGTGCCTGTTCGCCGCTCTCCCTAAGTCTGATTCTCATCGAGGCC CCTCGCTTCTATGACTGTGCTTGCAGAAGAGTAAACACTCTCGGATGCCGCTGTCCTGGGGGAGCCCGCGGGAGCCTGTGAATGTTGATA CGAGCTGGCCAGTCCTGGGCCCAGCTCACTTGTCCAGCTACCTGCCAGGTGGCTTTCACTGTGTTTAAAATACATTGCATTCCAAGCTGG TCCCCTCTGTGTATCACTCTACTGAGAAATCCTGCCTAGTGTGTTTTGGGATGTGTCCTAGCATTTACAAGAAAATGAAAAGCGTCCTCT TAATTGGCACCCGAATGTTGCTGTGGCTCAGTCACATATCCCAGGGCCCTCGTCCCGAGGCCGTGCTGCCCCGAGCCCCGAGCCCCTCTG CAGCTCACCCTTGGCTTGTTTTCCGCAAACCCGGTAAACGCAAGCCCTTGGGGCAGATGCAGAAGCAGAAGAGGGAGGGGAAACCTGCCT CTGGGTCACCCTGTTAGCACAGCGTTCTCATCGGGAGACAGCATGGAACTCTCTCTCGCAGTGCTCGAGGCTGTGTGTCAGTGTTTGCTG GGCTTGTGGCTCCTTTTTTGGCTGGATAAAGAAGTCGCTGTTTTTGTACTGCTTCTGTGGCTCTTCACAGACCTCACGGATGTGACCGGA GATGAGTGCCGATGACCACGTTTTAAAGGAGAAAGAGAGCTCCTGGTGGGGCCCTCGGGGTGGTCTCAGGTCCCATTTGCAGTCTGCAAC AGTGACGCGCAGCCCGGTCCGGAGCGTGGTGAGCTTTGTTTGCCTTCTGGGTCAGCTTTCGCTGTGTCTCCTGTGTGTGTTAGAATCCAG AGCCCAGAGGAAGTGCAAGCGGGTCCTCCGCCAACGGGGAGAGCCTCTTCGCGGCGCTGTTGGCGACAGCAGCGCTGTGATTCGCGTAGC AGGGGAGTTGTTTGAAACACCTTCCTGAGTAGTCCGGCCTTGTCAATGAGTGCTTGTTTTCCTTTAAACAGTCTGACATATTTACTCGTC ACTTTCAAACCAGAAGCATGAGAGGAAGGAGATATTGTGGGGTCCGTTTAACTCGATAGAAAGCGCAGGGGGATGGCCCCCGGCGCGGGC TCTTGACCCGCTCAGCGCTGACCCCACCGCCCTGGCCGAGGCACTTGGCCTTGCTGAGCTGGACTTCCTCCTCCTCCTCCTCATGACCGG GGTGAATTAGAACGTTTTTAAAGACACCCCCTTCCAAATTCTGTAACACATTGTAATTGGAGAAGAAGGAAACTCTGCAAGGCTAAACTG TCATTCACAACTTGGCTACACATAGACTCTAGTCAGTTTTGTCTCCAGAACCTTAGGCTTTTGTATTTTTTAATTTTAATTTCACTGTTA ATCCTTATTGTCTTTTTTATTAAGATGTTGGAAAAGCAGGAGGTAGTTGTGCCTCAATTATTGCAAAAATGTAACAATAAAGTTCCTCAA AATAAGATCTGTTCCTCATAGCTATACTGTGTACACATAAGACGCATATAGGGTTTTACTGAAATCTATTTTTAACTCTTATGTTCGTAG AGAAATTGTTTCAAGGATTTTGAGTCATAGGTCTGTAATTTATAGAGATCTCTAGAATTCTTATTGTAATTTTCCTACTTCTTTGATAAA AGAAAAATAAGTCAGATTGTTAACTCCAAGATTGAAAAAAAAAACTCTTGAAAGAAGATTATTAGTTGTAACTAATTTAGGGGTTCTGGG CACAGACATCTAACCTGGTATTGTAAGGCAGAGGCTCCCATTGGAATGGTAGTGGTCCGGGTCAGTTGTTCATGGTGTAAGCTTTGCACA GTGTATTAACATTGGGAGGGTCTGGCTTGAAAATTTGGCCACCCTCAGCCTCTGAATGTTTATTAAAATAAATTTAGTCTTTCTTTGCTT |
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FusionGenePPI for PRKAR1B_GNA12 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| PRKAR1B | PRKAR1A, AKAP1, PRKAR1B, EGFR, WNK1, CUL3, CALU, DUS3L, EEF2K, THG1L, PRKACA, PRKACB, MLF1, NAPG, RABGGTB, PRKAR2B, SFRP4, AP2M1, SYT11, DCLRE1C, VAPB, XPO1, GPR161, VAPA, NOX5, PRPSAP2, RAPGEF5, MRPS15, C6orf141, SKP2, PRKACG, ERMAP, ETFB, TRIM25 | GNA12 | CDH15, CDH1, CDH2, AKAP13, ARHGEF1, DRD5, PPP5C, S1PR4, PRKCB, PRKCE, PRKCD, ARHGEF12, TEC, F2R, TBXA2R, HSP90AA1, ARHGEF11, MAP3K5, ARHGEF28, PCK1, LRRK2, APP, IL3RA, GNB3, ARAF, GNAS, CDC73 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for PRKAR1B_GNA12 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for PRKAR1B_GNA12 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | GNA12 | C0009324 | Ulcerative Colitis | 1 | CTD_human |
| Tgene | GNA12 | C0033975 | Psychotic Disorders | 1 | PSYGENET |
| Tgene | GNA12 | C0151744 | Myocardial Ischemia | 1 | CTD_human |
| Tgene | GNA12 | C0349204 | Nonorganic psychosis | 1 | PSYGENET |
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