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Fusion gene ID: 28686 |
FusionGeneSummary for PRKAG2_NUB1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PRKAG2_NUB1 | Fusion gene ID: 28686 | Hgene | Tgene | Gene symbol | PRKAG2 | NUB1 | Gene ID | 51422 | 51667 |
| Gene name | protein kinase AMP-activated non-catalytic subunit gamma 2 | negative regulator of ubiquitin like proteins 1 | |
| Synonyms | AAKG|AAKG2|CMH6|H91620p|WPWS | BS4|NUB1L|NYREN18 | |
| Cytomap | 7q36.1 | 7q36.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | 5'-AMP-activated protein kinase subunit gamma-2AMPK subunit gamma-2protein kinase, AMP-activated, gamma 2 non-catalytic subunit | NEDD8 ultimate buster 1NEDD8 ultimate buster-1renal carcinoma antigen NY-REN-18 | |
| Modification date | 20180529 | 20180525 | |
| UniProtAcc | Q9UGJ0 | Q9Y5A7 | |
| Ensembl transtripts involved in fusion gene | ENST00000287878, ENST00000418337, ENST00000433631, ENST00000492843, ENST00000392801, ENST00000461529, | ENST00000413040, ENST00000568733, ENST00000566856, ENST00000355851, ENST00000477666, | |
| Fusion gene scores | * DoF score | 10 X 7 X 7=490 | 5 X 5 X 3=75 |
| # samples | 11 | 5 | |
| ** MAII score | log2(11/490*10)=-2.15527822547791 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(5/75*10)=-0.584962500721156 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: PRKAG2 [Title/Abstract] AND NUB1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | PRKAG2 | GO:0006469 | negative regulation of protein kinase activity | 17255938 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | OV | TCGA-13-1497-01A | PRKAG2 | chr7 | 151329155 | - | NUB1 | chr7 | 151042434 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000287878 | ENST00000413040 | PRKAG2 | chr7 | 151329155 | - | NUB1 | chr7 | 151042434 | + |
| In-frame | ENST00000287878 | ENST00000568733 | PRKAG2 | chr7 | 151329155 | - | NUB1 | chr7 | 151042434 | + |
| 5CDS-5UTR | ENST00000287878 | ENST00000566856 | PRKAG2 | chr7 | 151329155 | - | NUB1 | chr7 | 151042434 | + |
| 5CDS-5UTR | ENST00000287878 | ENST00000355851 | PRKAG2 | chr7 | 151329155 | - | NUB1 | chr7 | 151042434 | + |
| 5CDS-intron | ENST00000287878 | ENST00000477666 | PRKAG2 | chr7 | 151329155 | - | NUB1 | chr7 | 151042434 | + |
| Frame-shift | ENST00000418337 | ENST00000413040 | PRKAG2 | chr7 | 151329155 | - | NUB1 | chr7 | 151042434 | + |
| Frame-shift | ENST00000418337 | ENST00000568733 | PRKAG2 | chr7 | 151329155 | - | NUB1 | chr7 | 151042434 | + |
| 5CDS-5UTR | ENST00000418337 | ENST00000566856 | PRKAG2 | chr7 | 151329155 | - | NUB1 | chr7 | 151042434 | + |
| 5CDS-5UTR | ENST00000418337 | ENST00000355851 | PRKAG2 | chr7 | 151329155 | - | NUB1 | chr7 | 151042434 | + |
| 5CDS-intron | ENST00000418337 | ENST00000477666 | PRKAG2 | chr7 | 151329155 | - | NUB1 | chr7 | 151042434 | + |
| In-frame | ENST00000433631 | ENST00000413040 | PRKAG2 | chr7 | 151329155 | - | NUB1 | chr7 | 151042434 | + |
| In-frame | ENST00000433631 | ENST00000568733 | PRKAG2 | chr7 | 151329155 | - | NUB1 | chr7 | 151042434 | + |
| 5CDS-5UTR | ENST00000433631 | ENST00000566856 | PRKAG2 | chr7 | 151329155 | - | NUB1 | chr7 | 151042434 | + |
| 5CDS-5UTR | ENST00000433631 | ENST00000355851 | PRKAG2 | chr7 | 151329155 | - | NUB1 | chr7 | 151042434 | + |
| 5CDS-intron | ENST00000433631 | ENST00000477666 | PRKAG2 | chr7 | 151329155 | - | NUB1 | chr7 | 151042434 | + |
| In-frame | ENST00000492843 | ENST00000413040 | PRKAG2 | chr7 | 151329155 | - | NUB1 | chr7 | 151042434 | + |
| In-frame | ENST00000492843 | ENST00000568733 | PRKAG2 | chr7 | 151329155 | - | NUB1 | chr7 | 151042434 | + |
| 5CDS-5UTR | ENST00000492843 | ENST00000566856 | PRKAG2 | chr7 | 151329155 | - | NUB1 | chr7 | 151042434 | + |
| 5CDS-5UTR | ENST00000492843 | ENST00000355851 | PRKAG2 | chr7 | 151329155 | - | NUB1 | chr7 | 151042434 | + |
| 5CDS-intron | ENST00000492843 | ENST00000477666 | PRKAG2 | chr7 | 151329155 | - | NUB1 | chr7 | 151042434 | + |
| Frame-shift | ENST00000392801 | ENST00000413040 | PRKAG2 | chr7 | 151329155 | - | NUB1 | chr7 | 151042434 | + |
| Frame-shift | ENST00000392801 | ENST00000568733 | PRKAG2 | chr7 | 151329155 | - | NUB1 | chr7 | 151042434 | + |
| 5CDS-5UTR | ENST00000392801 | ENST00000566856 | PRKAG2 | chr7 | 151329155 | - | NUB1 | chr7 | 151042434 | + |
| 5CDS-5UTR | ENST00000392801 | ENST00000355851 | PRKAG2 | chr7 | 151329155 | - | NUB1 | chr7 | 151042434 | + |
| 5CDS-intron | ENST00000392801 | ENST00000477666 | PRKAG2 | chr7 | 151329155 | - | NUB1 | chr7 | 151042434 | + |
| intron-3CDS | ENST00000461529 | ENST00000413040 | PRKAG2 | chr7 | 151329155 | - | NUB1 | chr7 | 151042434 | + |
| intron-3CDS | ENST00000461529 | ENST00000568733 | PRKAG2 | chr7 | 151329155 | - | NUB1 | chr7 | 151042434 | + |
| intron-5UTR | ENST00000461529 | ENST00000566856 | PRKAG2 | chr7 | 151329155 | - | NUB1 | chr7 | 151042434 | + |
| intron-5UTR | ENST00000461529 | ENST00000355851 | PRKAG2 | chr7 | 151329155 | - | NUB1 | chr7 | 151042434 | + |
| intron-intron | ENST00000461529 | ENST00000477666 | PRKAG2 | chr7 | 151329155 | - | NUB1 | chr7 | 151042434 | + |
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FusionProtFeatures for PRKAG2_NUB1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| PRKAG2 | NUB1 |
| AMP/ATP-binding subunit of AMP-activated protein kinase(AMPK), an energy sensor protein kinase that plays a key role inregulating cellular energy metabolism. In response to reduction ofintracellular ATP levels, AMPK activates energy-producing pathwaysand inhibits energy-consuming processes: inhibits protein,carbohydrate and lipid biosynthesis, as well as cell growth andproliferation. AMPK acts via direct phosphorylation of metabolicenzymes, and by longer-term effects via phosphorylation oftranscription regulators. Also acts as a regulator of cellularpolarity by remodeling the actin cytoskeleton; probably byindirectly activating myosin. Gamma non-catalytic subunit mediatesbinding to AMP, ADP and ATP, leading to activate or inhibit AMPK:AMP-binding results in allosteric activation of alpha catalyticsubunit (PRKAA1 or PRKAA2) both by inducing phosphorylation andpreventing dephosphorylation of catalytic subunits. ADP alsostimulates phosphorylation, without stimulating alreadyphosphorylated catalytic subunit. ATP promotes dephosphorylationof catalytic subunit, rendering the AMPK enzyme inactive.{ECO:0000269|PubMed:14722619}. | Specific down-regulator of the NEDD8 conjugation system.Recruits NEDD8, UBD, and their conjugates to the proteasome fordegradation. Isoform 1 promotes the degradation of NEDD8 moreefficiently than isoform 2. {ECO:0000269|PubMed:16707496}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >NUB1 | chr7:151329155 | chr7:151042434 | ENST00000355851 | + | 0 | 15 | 152_203 | -1 | 616 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >NUB1 | chr7:151329155 | chr7:151042434 | ENST00000355851 | + | 0 | 15 | 36_70 | -1 | 616 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >NUB1 | chr7:151329155 | chr7:151042434 | ENST00000566856 | + | 0 | 15 | 152_203 | -1 | 602 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >NUB1 | chr7:151329155 | chr7:151042434 | ENST00000566856 | + | 0 | 15 | 36_70 | -1 | 602 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >NUB1 | chr7:151329155 | chr7:151042434 | ENST00000355851 | + | 0 | 15 | 374_413 | -1 | 616 | Domain | UBA 1 |
| Tgene | >NUB1 | chr7:151329155 | chr7:151042434 | ENST00000355851 | + | 0 | 15 | 424_470 | -1 | 616 | Domain | UBA 2 |
| Tgene | >NUB1 | chr7:151329155 | chr7:151042434 | ENST00000355851 | + | 0 | 15 | 489_529 | -1 | 616 | Domain | UBA 3 |
| Tgene | >NUB1 | chr7:151329155 | chr7:151042434 | ENST00000566856 | + | 0 | 15 | 374_413 | -1 | 602 | Domain | UBA 1 |
| Tgene | >NUB1 | chr7:151329155 | chr7:151042434 | ENST00000566856 | + | 0 | 15 | 424_470 | -1 | 602 | Domain | UBA 2 |
| Tgene | >NUB1 | chr7:151329155 | chr7:151042434 | ENST00000566856 | + | 0 | 15 | 489_529 | -1 | 602 | Domain | UBA 3 |
| Tgene | >NUB1 | chr7:151329155 | chr7:151042434 | ENST00000355851 | + | 0 | 15 | 414_431 | -1 | 616 | Motif | Nuclear localization signal |
| Tgene | >NUB1 | chr7:151329155 | chr7:151042434 | ENST00000566856 | + | 0 | 15 | 414_431 | -1 | 602 | Motif | Nuclear localization signal |
| Tgene | >NUB1 | chr7:151329155 | chr7:151042434 | ENST00000355851 | + | 0 | 15 | 427_474 | -1 | 616 | Region | Note=NEDD8-binding 1 |
| Tgene | >NUB1 | chr7:151329155 | chr7:151042434 | ENST00000355851 | + | 0 | 15 | 550_598 | -1 | 616 | Region | Note=NEDD8-binding 2 |
| Tgene | >NUB1 | chr7:151329155 | chr7:151042434 | ENST00000566856 | + | 0 | 15 | 427_474 | -1 | 602 | Region | Note=NEDD8-binding 1 |
| Tgene | >NUB1 | chr7:151329155 | chr7:151042434 | ENST00000566856 | + | 0 | 15 | 550_598 | -1 | 602 | Region | Note=NEDD8-binding 2 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >PRKAG2 | chr7:151329155 | chr7:151042434 | ENST00000287878 | - | 5 | 16 | 275_335 | 251 | 570 | Domain | CBS 1 |
| Hgene | >PRKAG2 | chr7:151329155 | chr7:151042434 | ENST00000287878 | - | 5 | 16 | 357_415 | 251 | 570 | Domain | CBS 2 |
| Hgene | >PRKAG2 | chr7:151329155 | chr7:151042434 | ENST00000287878 | - | 5 | 16 | 430_492 | 251 | 570 | Domain | CBS 3 |
| Hgene | >PRKAG2 | chr7:151329155 | chr7:151042434 | ENST00000287878 | - | 5 | 16 | 504_562 | 251 | 570 | Domain | CBS 4 |
| Hgene | >PRKAG2 | chr7:151329155 | chr7:151042434 | ENST00000392801 | - | 5 | 16 | 275_335 | 207 | 526 | Domain | CBS 1 |
| Hgene | >PRKAG2 | chr7:151329155 | chr7:151042434 | ENST00000392801 | - | 5 | 16 | 357_415 | 207 | 526 | Domain | CBS 2 |
| Hgene | >PRKAG2 | chr7:151329155 | chr7:151042434 | ENST00000392801 | - | 5 | 16 | 430_492 | 207 | 526 | Domain | CBS 3 |
| Hgene | >PRKAG2 | chr7:151329155 | chr7:151042434 | ENST00000392801 | - | 5 | 16 | 504_562 | 207 | 526 | Domain | CBS 4 |
| Hgene | >PRKAG2 | chr7:151329155 | chr7:151042434 | ENST00000418337 | - | 1 | 12 | 275_335 | 10 | 329 | Domain | CBS 1 |
| Hgene | >PRKAG2 | chr7:151329155 | chr7:151042434 | ENST00000418337 | - | 1 | 12 | 357_415 | 10 | 329 | Domain | CBS 2 |
| Hgene | >PRKAG2 | chr7:151329155 | chr7:151042434 | ENST00000418337 | - | 1 | 12 | 430_492 | 10 | 329 | Domain | CBS 3 |
| Hgene | >PRKAG2 | chr7:151329155 | chr7:151042434 | ENST00000418337 | - | 1 | 12 | 504_562 | 10 | 329 | Domain | CBS 4 |
| Hgene | >PRKAG2 | chr7:151329155 | chr7:151042434 | ENST00000287878 | - | 5 | 16 | 370_391 | 251 | 570 | Motif | Note=AMPK pseudosubstrate |
| Hgene | >PRKAG2 | chr7:151329155 | chr7:151042434 | ENST00000392801 | - | 5 | 16 | 370_391 | 207 | 526 | Motif | Note=AMPK pseudosubstrate |
| Hgene | >PRKAG2 | chr7:151329155 | chr7:151042434 | ENST00000418337 | - | 1 | 12 | 370_391 | 10 | 329 | Motif | Note=AMPK pseudosubstrate |
| Hgene | >PRKAG2 | chr7:151329155 | chr7:151042434 | ENST00000287878 | - | 5 | 16 | 319_322 | 251 | 570 | Nucleotide binding | AMP%2C ADP or ATP 1 |
| Hgene | >PRKAG2 | chr7:151329155 | chr7:151042434 | ENST00000287878 | - | 5 | 16 | 383_384 | 251 | 570 | Nucleotide binding | AMP%2C ADP or ATP 1 |
| Hgene | >PRKAG2 | chr7:151329155 | chr7:151042434 | ENST00000287878 | - | 5 | 16 | 458_459 | 251 | 570 | Nucleotide binding | AMP 3 |
| Hgene | >PRKAG2 | chr7:151329155 | chr7:151042434 | ENST00000287878 | - | 5 | 16 | 474_477 | 251 | 570 | Nucleotide binding | AMP%2C ADP or ATP 2 |
| Hgene | >PRKAG2 | chr7:151329155 | chr7:151042434 | ENST00000287878 | - | 5 | 16 | 530_531 | 251 | 570 | Nucleotide binding | AMP%2C ADP or ATP 2 |
| Hgene | >PRKAG2 | chr7:151329155 | chr7:151042434 | ENST00000287878 | - | 5 | 16 | 546_549 | 251 | 570 | Nucleotide binding | AMP 3 |
| Hgene | >PRKAG2 | chr7:151329155 | chr7:151042434 | ENST00000392801 | - | 5 | 16 | 319_322 | 207 | 526 | Nucleotide binding | AMP%2C ADP or ATP 1 |
| Hgene | >PRKAG2 | chr7:151329155 | chr7:151042434 | ENST00000392801 | - | 5 | 16 | 383_384 | 207 | 526 | Nucleotide binding | AMP%2C ADP or ATP 1 |
| Hgene | >PRKAG2 | chr7:151329155 | chr7:151042434 | ENST00000392801 | - | 5 | 16 | 458_459 | 207 | 526 | Nucleotide binding | AMP 3 |
| Hgene | >PRKAG2 | chr7:151329155 | chr7:151042434 | ENST00000392801 | - | 5 | 16 | 474_477 | 207 | 526 | Nucleotide binding | AMP%2C ADP or ATP 2 |
| Hgene | >PRKAG2 | chr7:151329155 | chr7:151042434 | ENST00000392801 | - | 5 | 16 | 530_531 | 207 | 526 | Nucleotide binding | AMP%2C ADP or ATP 2 |
| Hgene | >PRKAG2 | chr7:151329155 | chr7:151042434 | ENST00000392801 | - | 5 | 16 | 546_549 | 207 | 526 | Nucleotide binding | AMP 3 |
| Hgene | >PRKAG2 | chr7:151329155 | chr7:151042434 | ENST00000418337 | - | 1 | 12 | 319_322 | 10 | 329 | Nucleotide binding | AMP%2C ADP or ATP 1 |
| Hgene | >PRKAG2 | chr7:151329155 | chr7:151042434 | ENST00000418337 | - | 1 | 12 | 383_384 | 10 | 329 | Nucleotide binding | AMP%2C ADP or ATP 1 |
| Hgene | >PRKAG2 | chr7:151329155 | chr7:151042434 | ENST00000418337 | - | 1 | 12 | 458_459 | 10 | 329 | Nucleotide binding | AMP 3 |
| Hgene | >PRKAG2 | chr7:151329155 | chr7:151042434 | ENST00000418337 | - | 1 | 12 | 474_477 | 10 | 329 | Nucleotide binding | AMP%2C ADP or ATP 2 |
| Hgene | >PRKAG2 | chr7:151329155 | chr7:151042434 | ENST00000418337 | - | 1 | 12 | 530_531 | 10 | 329 | Nucleotide binding | AMP%2C ADP or ATP 2 |
| Hgene | >PRKAG2 | chr7:151329155 | chr7:151042434 | ENST00000418337 | - | 1 | 12 | 546_549 | 10 | 329 | Nucleotide binding | AMP 3 |
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FusionGeneSequence for PRKAG2_NUB1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_PRKAG2_ENST00000287878_chr7_151329155_-_NUB1_ENST00000413040_chr7_151042434_+_854aa MGSAVMDTKKKKDVSSPGGSGGKKNASQKRRSLRVHIPDLSSFAMPLLDGDLEGSGKHSSRKVDSPFGPGSPSKGFFSRGPQPRPSSPMS APVRPKTSPGSPKTVFPFSYQESPPRSPRRMSFSGIFRSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLESY KHEPERLENRIYASSSPPDTGQRFCPSSFQSPTRPPLASPTHYAPSKAAALAAALGPAEAGMLEKLEFEDEGMAQKKYLQAKLTQFLRED RIQLWKPPYTDENKKVGLALKDLAKQYSDRLECCENEVEKVIEEIRCKAIERGTGNDNYRTTGIATIEVFLPPRLKKDRKNLLETRLHIT GRELRSKIAETFGLQENYIKIVINKKQLQLGKTLEEQGVAHNVKAMVLELKQSEEDARKNFQLEEEEQNEAKLKEKQIQRTKRGLEILAK RAAETVVDPEMTPYLDIANQTGRSIRIPPSERKALMLAMGYHEKGRAFLKRKEYGIALPCLLDADKYFCECCRELLDTVDNYAVLQLDIV WCYFRLEQLECLDDAEKKLNLAQKCFKNCYGENHQRLVHIKGNCGKEKVLFLRLYLLQGIRNYHSGNDVEAYEYLNKARQLFKELYIDPS KVDNLLQLGFTAQEARLGLRACDGNVDHAATHITNRREELAQIRKEEKEKKRRRLENIRFLKGMGYSTHAAQQILLSNPQMWWLNDSNPE TDNRQESPSQENIDRLVYMGFDALVAEAALRVFRGNVQLAAQTLAHNGGSLPPELPLSPEDSLSPPATSPSDSAGTSSASTDEDMETEAV >In-frame_PRKAG2_ENST00000287878_chr7_151329155_-_NUB1_ENST00000568733_chr7_151042434_+_868aa MGSAVMDTKKKKDVSSPGGSGGKKNASQKRRSLRVHIPDLSSFAMPLLDGDLEGSGKHSSRKVDSPFGPGSPSKGFFSRGPQPRPSSPMS APVRPKTSPGSPKTVFPFSYQESPPRSPRRMSFSGIFRSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLESY KHEPERLENRIYASSSPPDTGQRFCPSSFQSPTRPPLASPTHYAPSKAAALAAALGPAEAGMLEKLEFEDEGMAQKKYLQAKLTQFLRED RIQLWKPPYTDENKKVGLALKDLAKQYSDRLECCENEVEKVIEEIRCKAIERGTGNDNYRTTGIATIEVFLPPRLKKDRKNLLETRLHIT GRELRSKIAETFGLQENYIKIVINKKQLQLGKTLEEQGVAHNVKAMVLELKQSEEDARKNFQLEEEEQNEAKLKEKQIQRTKRGLEILAK RAAETVVDPEMTPYLDIANQTGRSIRIPPSERKALMLAMGYHEKGRAFLKRKEYGIALPCLLDADKYFCECCRELLDTVDNYAVLQLDIV WCYFRLEQLECLDDAEKKLNLAQKCFKNCYGENHQRLVHIKGNCGKEKVLFLRLYLLQGIRNYHSGNDVEAYEYLNKARQLFKELYIDPS KVDNLLQLGFTAQEARLGLRACDGNVDHAATHITNRREELAQIRKEEKEKKRRRLENIRFLKGMGYSTHAAQQVLHAASGNLDEALKILL SNPQMWWLNDSNPETDNRQESPSQENIDRLVYMGFDALVAEAALRVFRGNVQLAAQTLAHNGGSLPPELPLSPEDSLSPPATSPSDSAGT >In-frame_PRKAG2_ENST00000433631_chr7_151329155_-_NUB1_ENST00000413040_chr7_151042434_+_730aa MKRFGSLRSNKKHKDQNRSTERRQSEPHGLFASGLSSSPSTPTQVTKQHTFPLESYKHEPERLENRIYASSSPPDTGQRFCPSSFQSPTR PPLASPTHYAPSKAAALAAALGPAEAGMLEKLEFEDEGMAQKKYLQAKLTQFLREDRIQLWKPPYTDENKKVGLALKDLAKQYSDRLECC ENEVEKVIEEIRCKAIERGTGNDNYRTTGIATIEVFLPPRLKKDRKNLLETRLHITGRELRSKIAETFGLQENYIKIVINKKQLQLGKTL EEQGVAHNVKAMVLELKQSEEDARKNFQLEEEEQNEAKLKEKQIQRTKRGLEILAKRAAETVVDPEMTPYLDIANQTGRSIRIPPSERKA LMLAMGYHEKGRAFLKRKEYGIALPCLLDADKYFCECCRELLDTVDNYAVLQLDIVWCYFRLEQLECLDDAEKKLNLAQKCFKNCYGENH QRLVHIKGNCGKEKVLFLRLYLLQGIRNYHSGNDVEAYEYLNKARQLFKELYIDPSKVDNLLQLGFTAQEARLGLRACDGNVDHAATHIT NRREELAQIRKEEKEKKRRRLENIRFLKGMGYSTHAAQQILLSNPQMWWLNDSNPETDNRQESPSQENIDRLVYMGFDALVAEAALRVFR GNVQLAAQTLAHNGGSLPPELPLSPEDSLSPPATSPSDSAGTSSASTDEDMETEAVNEILEDIPEHEEDYLDSTLEDEEIIIAEYLSYVE >In-frame_PRKAG2_ENST00000433631_chr7_151329155_-_NUB1_ENST00000568733_chr7_151042434_+_744aa MKRFGSLRSNKKHKDQNRSTERRQSEPHGLFASGLSSSPSTPTQVTKQHTFPLESYKHEPERLENRIYASSSPPDTGQRFCPSSFQSPTR PPLASPTHYAPSKAAALAAALGPAEAGMLEKLEFEDEGMAQKKYLQAKLTQFLREDRIQLWKPPYTDENKKVGLALKDLAKQYSDRLECC ENEVEKVIEEIRCKAIERGTGNDNYRTTGIATIEVFLPPRLKKDRKNLLETRLHITGRELRSKIAETFGLQENYIKIVINKKQLQLGKTL EEQGVAHNVKAMVLELKQSEEDARKNFQLEEEEQNEAKLKEKQIQRTKRGLEILAKRAAETVVDPEMTPYLDIANQTGRSIRIPPSERKA LMLAMGYHEKGRAFLKRKEYGIALPCLLDADKYFCECCRELLDTVDNYAVLQLDIVWCYFRLEQLECLDDAEKKLNLAQKCFKNCYGENH QRLVHIKGNCGKEKVLFLRLYLLQGIRNYHSGNDVEAYEYLNKARQLFKELYIDPSKVDNLLQLGFTAQEARLGLRACDGNVDHAATHIT NRREELAQIRKEEKEKKRRRLENIRFLKGMGYSTHAAQQVLHAASGNLDEALKILLSNPQMWWLNDSNPETDNRQESPSQENIDRLVYMG FDALVAEAALRVFRGNVQLAAQTLAHNGGSLPPELPLSPEDSLSPPATSPSDSAGTSSASTDEDMETEAVNEILEDIPEHEEDYLDSTLE >In-frame_PRKAG2_ENST00000492843_chr7_151329155_-_NUB1_ENST00000413040_chr7_151042434_+_730aa MKRFGSLRSNKKHKDQNRSTERRQSEPHGLFASGLSSSPSTPTQVTKQHTFPLESYKHEPERLENRIYASSSPPDTGQRFCPSSFQSPTR PPLASPTHYAPSKAAALAAALGPAEAGMLEKLEFEDEGMAQKKYLQAKLTQFLREDRIQLWKPPYTDENKKVGLALKDLAKQYSDRLECC ENEVEKVIEEIRCKAIERGTGNDNYRTTGIATIEVFLPPRLKKDRKNLLETRLHITGRELRSKIAETFGLQENYIKIVINKKQLQLGKTL EEQGVAHNVKAMVLELKQSEEDARKNFQLEEEEQNEAKLKEKQIQRTKRGLEILAKRAAETVVDPEMTPYLDIANQTGRSIRIPPSERKA LMLAMGYHEKGRAFLKRKEYGIALPCLLDADKYFCECCRELLDTVDNYAVLQLDIVWCYFRLEQLECLDDAEKKLNLAQKCFKNCYGENH QRLVHIKGNCGKEKVLFLRLYLLQGIRNYHSGNDVEAYEYLNKARQLFKELYIDPSKVDNLLQLGFTAQEARLGLRACDGNVDHAATHIT NRREELAQIRKEEKEKKRRRLENIRFLKGMGYSTHAAQQILLSNPQMWWLNDSNPETDNRQESPSQENIDRLVYMGFDALVAEAALRVFR GNVQLAAQTLAHNGGSLPPELPLSPEDSLSPPATSPSDSAGTSSASTDEDMETEAVNEILEDIPEHEEDYLDSTLEDEEIIIAEYLSYVE >In-frame_PRKAG2_ENST00000492843_chr7_151329155_-_NUB1_ENST00000568733_chr7_151042434_+_744aa MKRFGSLRSNKKHKDQNRSTERRQSEPHGLFASGLSSSPSTPTQVTKQHTFPLESYKHEPERLENRIYASSSPPDTGQRFCPSSFQSPTR PPLASPTHYAPSKAAALAAALGPAEAGMLEKLEFEDEGMAQKKYLQAKLTQFLREDRIQLWKPPYTDENKKVGLALKDLAKQYSDRLECC ENEVEKVIEEIRCKAIERGTGNDNYRTTGIATIEVFLPPRLKKDRKNLLETRLHITGRELRSKIAETFGLQENYIKIVINKKQLQLGKTL EEQGVAHNVKAMVLELKQSEEDARKNFQLEEEEQNEAKLKEKQIQRTKRGLEILAKRAAETVVDPEMTPYLDIANQTGRSIRIPPSERKA LMLAMGYHEKGRAFLKRKEYGIALPCLLDADKYFCECCRELLDTVDNYAVLQLDIVWCYFRLEQLECLDDAEKKLNLAQKCFKNCYGENH QRLVHIKGNCGKEKVLFLRLYLLQGIRNYHSGNDVEAYEYLNKARQLFKELYIDPSKVDNLLQLGFTAQEARLGLRACDGNVDHAATHIT NRREELAQIRKEEKEKKRRRLENIRFLKGMGYSTHAAQQVLHAASGNLDEALKILLSNPQMWWLNDSNPETDNRQESPSQENIDRLVYMG FDALVAEAALRVFRGNVQLAAQTLAHNGGSLPPELPLSPEDSLSPPATSPSDSAGTSSASTDEDMETEAVNEILEDIPEHEEDYLDSTLE |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_PRKAG2_ENST00000287878_chr7_151329155_-_NUB1_ENST00000413040_chr7_151042434_+_2562nt ATGGGAAGCGCGGTTATGGACACCAAGAAGAAAAAAGATGTTTCCAGCCCCGGCGGGAGCGGCGGCAAGAAAAATGCCAGCCAGAAGAGG CGTTCGCTGCGCGTGCACATTCCGGACCTGAGCTCCTTCGCCATGCCGCTCCTGGACGGAGACCTGGAGGGTTCCGGAAAGCATTCCTCT CGAAAGGTGGACAGCCCCTTCGGCCCGGGCAGCCCCTCCAAAGGGTTCTTCTCCAGAGGCCCCCAGCCCCGGCCCTCCAGCCCCATGTCT GCACCTGTGAGGCCCAAGACCAGCCCCGGCTCTCCCAAAACCGTGTTCCCGTTCTCCTACCAGGAGTCCCCGCCACGCTCCCCTCGACGC ATGAGCTTCAGTGGGATCTTCCGCTCCTCCTCCAAAGAGTCTTCCCCCAACTCCAACCCTGCTACCTCGCCCGGGGGCATCAGGTTTTTC TCCCGCTCCAGAAAAACCTCCGGCCTCTCCTCCTCTCCGTCAACACCCACCCAAGTGACCAAGCAGCACACGTTTCCCCTGGAATCCTAT AAGCACGAGCCTGAACGGTTAGAGAATCGCATCTATGCCTCGTCTTCCCCCCCGGACACAGGGCAGAGGTTCTGCCCGTCTTCCTTCCAG AGCCCGACCAGGCCTCCACTGGCATCACCGACACACTATGCTCCCTCCAAAGCCGCGGCGCTGGCGGCGGCCCTGGGACCCGCGGAAGCC GGCATGCTGGAGAAGCTGGAGTTCGAGGACGAAGGGATGGCACAAAAGAAATATCTTCAAGCAAAATTGACCCAGTTTTTAAGGGAAGAC AGGATTCAACTTTGGAAACCTCCATATACAGATGAAAATAAAAAAGTTGGTTTGGCATTAAAGGACCTTGCTAAGCAGTACTCTGACAGA CTAGAATGCTGTGAAAATGAAGTAGAAAAGGTAATAGAAGAAATACGTTGCAAGGCAATTGAGCGTGGAACAGGAAATGACAATTATAGA ACAACGGGAATTGCTACAATCGAGGTGTTTTTACCACCAAGACTAAAAAAAGATAGGAAAAACTTGTTGGAGACCCGATTGCACATCACT GGCAGAGAACTGAGGTCCAAAATAGCTGAAACCTTTGGACTTCAAGAAAATTATATCAAAATTGTCATAAATAAGAAGCAACTACAACTA GGGAAAACCCTTGAAGAACAAGGCGTGGCTCACAATGTGAAAGCGATGGTGCTTGAACTAAAACAATCTGAAGAGGACGCGAGGAAAAAC TTCCAGTTAGAGGAAGAGGAGCAAAATGAGGCCAAACTCAAAGAAAAACAAATTCAGAGGACCAAGAGAGGACTAGAAATACTGGCAAAG AGAGCAGCAGAGACAGTGGTGGATCCAGAAATGACACCGTACTTAGACATAGCTAACCAGACAGGCAGATCAATCAGAATTCCCCCATCA GAAAGAAAAGCCCTTATGTTAGCTATGGGATATCATGAGAAGGGCAGAGCTTTCCTGAAAAGAAAAGAATATGGAATAGCCTTGCCATGT CTGTTGGACGCTGACAAATATTTCTGTGAGTGTTGCAGAGAGCTGCTGGACACAGTGGATAACTACGCCGTCCTCCAGCTGGATATAGTG TGGTGTTACTTCCGCCTGGAACAGCTGGAATGCCTTGATGATGCAGAAAAAAAATTAAACTTGGCCCAGAAATGCTTTAAAAATTGTTAC GGAGAAAATCATCAGAGACTGGTCCACATAAAAGGAAATTGTGGGAAAGAGAAGGTACTGTTTCTAAGACTCTACTTACTTCAAGGGATC CGAAACTATCACAGTGGAAATGATGTAGAGGCTTATGAGTATCTTAACAAGGCACGTCAGCTCTTTAAAGAGCTATATATTGATCCATCA AAAGTGGACAATTTGTTGCAGTTGGGGTTTACTGCCCAGGAAGCCCGGCTTGGCCTGAGGGCGTGTGATGGGAACGTGGATCATGCGGCC ACTCATATTACCAACCGCAGAGAGGAACTGGCCCAAATAAGGAAGGAGGAAAAAGAGAAGAAAAGACGCCGCCTCGAGAACATCAGGTTT CTGAAAGGGATGGGCTACTCCACGCACGCGGCCCAGCAGATTCTGCTCAGCAATCCTCAGATGTGGTGGTTAAATGATTCCAATCCTGAA ACCGACAACCGTCAAGAAAGTCCTTCCCAGGAAAACATTGACCGATTGGTGTACATGGGTTTTGATGCACTCGTGGCCGAAGCTGCGCTG AGAGTGTTCAGAGGCAACGTCCAGCTGGCCGCCCAGACCCTTGCTCACAACGGAGGAAGCCTGCCTCCCGAGCTGCCGCTGTCGCCAGAA GACTCTTTGTCCCCGCCAGCCACGTCCCCTTCTGACTCCGCAGGAACCTCTAGTGCCTCAACAGACGAAGACATGGAGACAGAGGCCGTC AATGAGATACTGGAAGACATTCCAGAGCATGAGGAAGACTATCTTGACTCAACTCTGGAAGATGAAGAAATTATTATTGCAGAGTACCTA >In-frame_PRKAG2_ENST00000287878_chr7_151329155_-_NUB1_ENST00000568733_chr7_151042434_+_2604nt ATGGGAAGCGCGGTTATGGACACCAAGAAGAAAAAAGATGTTTCCAGCCCCGGCGGGAGCGGCGGCAAGAAAAATGCCAGCCAGAAGAGG CGTTCGCTGCGCGTGCACATTCCGGACCTGAGCTCCTTCGCCATGCCGCTCCTGGACGGAGACCTGGAGGGTTCCGGAAAGCATTCCTCT CGAAAGGTGGACAGCCCCTTCGGCCCGGGCAGCCCCTCCAAAGGGTTCTTCTCCAGAGGCCCCCAGCCCCGGCCCTCCAGCCCCATGTCT GCACCTGTGAGGCCCAAGACCAGCCCCGGCTCTCCCAAAACCGTGTTCCCGTTCTCCTACCAGGAGTCCCCGCCACGCTCCCCTCGACGC ATGAGCTTCAGTGGGATCTTCCGCTCCTCCTCCAAAGAGTCTTCCCCCAACTCCAACCCTGCTACCTCGCCCGGGGGCATCAGGTTTTTC TCCCGCTCCAGAAAAACCTCCGGCCTCTCCTCCTCTCCGTCAACACCCACCCAAGTGACCAAGCAGCACACGTTTCCCCTGGAATCCTAT AAGCACGAGCCTGAACGGTTAGAGAATCGCATCTATGCCTCGTCTTCCCCCCCGGACACAGGGCAGAGGTTCTGCCCGTCTTCCTTCCAG AGCCCGACCAGGCCTCCACTGGCATCACCGACACACTATGCTCCCTCCAAAGCCGCGGCGCTGGCGGCGGCCCTGGGACCCGCGGAAGCC GGCATGCTGGAGAAGCTGGAGTTCGAGGACGAAGGGATGGCACAAAAGAAATATCTTCAAGCAAAATTGACCCAGTTTTTAAGGGAAGAC AGGATTCAACTTTGGAAACCTCCATATACAGATGAAAATAAAAAAGTTGGTTTGGCATTAAAGGACCTTGCTAAGCAGTACTCTGACAGA CTAGAATGCTGTGAAAATGAAGTAGAAAAGGTAATAGAAGAAATACGTTGCAAGGCAATTGAGCGTGGAACAGGAAATGACAATTATAGA ACAACGGGAATTGCTACAATCGAGGTGTTTTTACCACCAAGACTAAAAAAAGATAGGAAAAACTTGTTGGAGACCCGATTGCACATCACT GGCAGAGAACTGAGGTCCAAAATAGCTGAAACCTTTGGACTTCAAGAAAATTATATCAAAATTGTCATAAATAAGAAGCAACTACAACTA GGGAAAACCCTTGAAGAACAAGGCGTGGCTCACAATGTGAAAGCGATGGTGCTTGAACTAAAACAATCTGAAGAGGACGCGAGGAAAAAC TTCCAGTTAGAGGAAGAGGAGCAAAATGAGGCCAAACTCAAAGAAAAACAAATTCAGAGGACCAAGAGAGGACTAGAAATACTGGCAAAG AGAGCAGCAGAGACAGTGGTGGATCCAGAAATGACACCGTACTTAGACATAGCTAACCAGACAGGCAGATCAATCAGAATTCCCCCATCA GAAAGAAAAGCCCTTATGTTAGCTATGGGATATCATGAGAAGGGCAGAGCTTTCCTGAAAAGAAAAGAATATGGAATAGCCTTGCCATGT CTGTTGGACGCTGACAAATATTTCTGTGAGTGTTGCAGAGAGCTGCTGGACACAGTGGATAACTACGCCGTCCTCCAGCTGGATATAGTG TGGTGTTACTTCCGCCTGGAACAGCTGGAATGCCTTGATGATGCAGAAAAAAAATTAAACTTGGCCCAGAAATGCTTTAAAAATTGTTAC GGAGAAAATCATCAGAGACTGGTCCACATAAAAGGAAATTGTGGGAAAGAGAAGGTACTGTTTCTAAGACTCTACTTACTTCAAGGGATC CGAAACTATCACAGTGGAAATGATGTAGAGGCTTATGAGTATCTTAACAAGGCACGTCAGCTCTTTAAAGAGCTATATATTGATCCATCA AAAGTGGACAATTTGTTGCAGTTGGGGTTTACTGCCCAGGAAGCCCGGCTTGGCCTGAGGGCGTGTGATGGGAACGTGGATCATGCGGCC ACTCATATTACCAACCGCAGAGAGGAACTGGCCCAAATAAGGAAGGAGGAAAAAGAGAAGAAAAGACGCCGCCTCGAGAACATCAGGTTT CTGAAAGGGATGGGCTACTCCACGCACGCGGCCCAGCAGGTACTCCACGCAGCCAGCGGGAACTTGGATGAGGCCCTGAAGATTCTGCTC AGCAATCCTCAGATGTGGTGGTTAAATGATTCCAATCCTGAAACCGACAACCGTCAAGAAAGTCCTTCCCAGGAAAACATTGACCGATTG GTGTACATGGGTTTTGATGCACTCGTGGCCGAAGCTGCGCTGAGAGTGTTCAGAGGCAACGTCCAGCTGGCCGCCCAGACCCTTGCTCAC AACGGAGGAAGCCTGCCTCCCGAGCTGCCGCTGTCGCCAGAAGACTCTTTGTCCCCGCCAGCCACGTCCCCTTCTGACTCCGCAGGAACC TCTAGTGCCTCAACAGACGAAGACATGGAGACAGAGGCCGTCAATGAGATACTGGAAGACATTCCAGAGCATGAGGAAGACTATCTTGAC >In-frame_PRKAG2_ENST00000433631_chr7_151329155_-_NUB1_ENST00000413040_chr7_151042434_+_2190nt ATGAAGCGCTTTGGGAGCCTCAGGAGCAACAAGAAACACAAGGACCAAAATCGAAGCACGGAGAGGCGCCAGTCGGAGCCTCATGGCCTT TTCGCCTCCGGCCTCTCCTCCTCTCCGTCAACACCCACCCAAGTGACCAAGCAGCACACGTTTCCCCTGGAATCCTATAAGCACGAGCCT GAACGGTTAGAGAATCGCATCTATGCCTCGTCTTCCCCCCCGGACACAGGGCAGAGGTTCTGCCCGTCTTCCTTCCAGAGCCCGACCAGG CCTCCACTGGCATCACCGACACACTATGCTCCCTCCAAAGCCGCGGCGCTGGCGGCGGCCCTGGGACCCGCGGAAGCCGGCATGCTGGAG AAGCTGGAGTTCGAGGACGAAGGGATGGCACAAAAGAAATATCTTCAAGCAAAATTGACCCAGTTTTTAAGGGAAGACAGGATTCAACTT TGGAAACCTCCATATACAGATGAAAATAAAAAAGTTGGTTTGGCATTAAAGGACCTTGCTAAGCAGTACTCTGACAGACTAGAATGCTGT GAAAATGAAGTAGAAAAGGTAATAGAAGAAATACGTTGCAAGGCAATTGAGCGTGGAACAGGAAATGACAATTATAGAACAACGGGAATT GCTACAATCGAGGTGTTTTTACCACCAAGACTAAAAAAAGATAGGAAAAACTTGTTGGAGACCCGATTGCACATCACTGGCAGAGAACTG AGGTCCAAAATAGCTGAAACCTTTGGACTTCAAGAAAATTATATCAAAATTGTCATAAATAAGAAGCAACTACAACTAGGGAAAACCCTT GAAGAACAAGGCGTGGCTCACAATGTGAAAGCGATGGTGCTTGAACTAAAACAATCTGAAGAGGACGCGAGGAAAAACTTCCAGTTAGAG GAAGAGGAGCAAAATGAGGCCAAACTCAAAGAAAAACAAATTCAGAGGACCAAGAGAGGACTAGAAATACTGGCAAAGAGAGCAGCAGAG ACAGTGGTGGATCCAGAAATGACACCGTACTTAGACATAGCTAACCAGACAGGCAGATCAATCAGAATTCCCCCATCAGAAAGAAAAGCC CTTATGTTAGCTATGGGATATCATGAGAAGGGCAGAGCTTTCCTGAAAAGAAAAGAATATGGAATAGCCTTGCCATGTCTGTTGGACGCT GACAAATATTTCTGTGAGTGTTGCAGAGAGCTGCTGGACACAGTGGATAACTACGCCGTCCTCCAGCTGGATATAGTGTGGTGTTACTTC CGCCTGGAACAGCTGGAATGCCTTGATGATGCAGAAAAAAAATTAAACTTGGCCCAGAAATGCTTTAAAAATTGTTACGGAGAAAATCAT CAGAGACTGGTCCACATAAAAGGAAATTGTGGGAAAGAGAAGGTACTGTTTCTAAGACTCTACTTACTTCAAGGGATCCGAAACTATCAC AGTGGAAATGATGTAGAGGCTTATGAGTATCTTAACAAGGCACGTCAGCTCTTTAAAGAGCTATATATTGATCCATCAAAAGTGGACAAT TTGTTGCAGTTGGGGTTTACTGCCCAGGAAGCCCGGCTTGGCCTGAGGGCGTGTGATGGGAACGTGGATCATGCGGCCACTCATATTACC AACCGCAGAGAGGAACTGGCCCAAATAAGGAAGGAGGAAAAAGAGAAGAAAAGACGCCGCCTCGAGAACATCAGGTTTCTGAAAGGGATG GGCTACTCCACGCACGCGGCCCAGCAGATTCTGCTCAGCAATCCTCAGATGTGGTGGTTAAATGATTCCAATCCTGAAACCGACAACCGT CAAGAAAGTCCTTCCCAGGAAAACATTGACCGATTGGTGTACATGGGTTTTGATGCACTCGTGGCCGAAGCTGCGCTGAGAGTGTTCAGA GGCAACGTCCAGCTGGCCGCCCAGACCCTTGCTCACAACGGAGGAAGCCTGCCTCCCGAGCTGCCGCTGTCGCCAGAAGACTCTTTGTCC CCGCCAGCCACGTCCCCTTCTGACTCCGCAGGAACCTCTAGTGCCTCAACAGACGAAGACATGGAGACAGAGGCCGTCAATGAGATACTG GAAGACATTCCAGAGCATGAGGAAGACTATCTTGACTCAACTCTGGAAGATGAAGAAATTATTATTGCAGAGTACCTATCCTATGTAGAA >In-frame_PRKAG2_ENST00000433631_chr7_151329155_-_NUB1_ENST00000568733_chr7_151042434_+_2232nt ATGAAGCGCTTTGGGAGCCTCAGGAGCAACAAGAAACACAAGGACCAAAATCGAAGCACGGAGAGGCGCCAGTCGGAGCCTCATGGCCTT TTCGCCTCCGGCCTCTCCTCCTCTCCGTCAACACCCACCCAAGTGACCAAGCAGCACACGTTTCCCCTGGAATCCTATAAGCACGAGCCT GAACGGTTAGAGAATCGCATCTATGCCTCGTCTTCCCCCCCGGACACAGGGCAGAGGTTCTGCCCGTCTTCCTTCCAGAGCCCGACCAGG CCTCCACTGGCATCACCGACACACTATGCTCCCTCCAAAGCCGCGGCGCTGGCGGCGGCCCTGGGACCCGCGGAAGCCGGCATGCTGGAG AAGCTGGAGTTCGAGGACGAAGGGATGGCACAAAAGAAATATCTTCAAGCAAAATTGACCCAGTTTTTAAGGGAAGACAGGATTCAACTT TGGAAACCTCCATATACAGATGAAAATAAAAAAGTTGGTTTGGCATTAAAGGACCTTGCTAAGCAGTACTCTGACAGACTAGAATGCTGT GAAAATGAAGTAGAAAAGGTAATAGAAGAAATACGTTGCAAGGCAATTGAGCGTGGAACAGGAAATGACAATTATAGAACAACGGGAATT GCTACAATCGAGGTGTTTTTACCACCAAGACTAAAAAAAGATAGGAAAAACTTGTTGGAGACCCGATTGCACATCACTGGCAGAGAACTG AGGTCCAAAATAGCTGAAACCTTTGGACTTCAAGAAAATTATATCAAAATTGTCATAAATAAGAAGCAACTACAACTAGGGAAAACCCTT GAAGAACAAGGCGTGGCTCACAATGTGAAAGCGATGGTGCTTGAACTAAAACAATCTGAAGAGGACGCGAGGAAAAACTTCCAGTTAGAG GAAGAGGAGCAAAATGAGGCCAAACTCAAAGAAAAACAAATTCAGAGGACCAAGAGAGGACTAGAAATACTGGCAAAGAGAGCAGCAGAG ACAGTGGTGGATCCAGAAATGACACCGTACTTAGACATAGCTAACCAGACAGGCAGATCAATCAGAATTCCCCCATCAGAAAGAAAAGCC CTTATGTTAGCTATGGGATATCATGAGAAGGGCAGAGCTTTCCTGAAAAGAAAAGAATATGGAATAGCCTTGCCATGTCTGTTGGACGCT GACAAATATTTCTGTGAGTGTTGCAGAGAGCTGCTGGACACAGTGGATAACTACGCCGTCCTCCAGCTGGATATAGTGTGGTGTTACTTC CGCCTGGAACAGCTGGAATGCCTTGATGATGCAGAAAAAAAATTAAACTTGGCCCAGAAATGCTTTAAAAATTGTTACGGAGAAAATCAT CAGAGACTGGTCCACATAAAAGGAAATTGTGGGAAAGAGAAGGTACTGTTTCTAAGACTCTACTTACTTCAAGGGATCCGAAACTATCAC AGTGGAAATGATGTAGAGGCTTATGAGTATCTTAACAAGGCACGTCAGCTCTTTAAAGAGCTATATATTGATCCATCAAAAGTGGACAAT TTGTTGCAGTTGGGGTTTACTGCCCAGGAAGCCCGGCTTGGCCTGAGGGCGTGTGATGGGAACGTGGATCATGCGGCCACTCATATTACC AACCGCAGAGAGGAACTGGCCCAAATAAGGAAGGAGGAAAAAGAGAAGAAAAGACGCCGCCTCGAGAACATCAGGTTTCTGAAAGGGATG GGCTACTCCACGCACGCGGCCCAGCAGGTACTCCACGCAGCCAGCGGGAACTTGGATGAGGCCCTGAAGATTCTGCTCAGCAATCCTCAG ATGTGGTGGTTAAATGATTCCAATCCTGAAACCGACAACCGTCAAGAAAGTCCTTCCCAGGAAAACATTGACCGATTGGTGTACATGGGT TTTGATGCACTCGTGGCCGAAGCTGCGCTGAGAGTGTTCAGAGGCAACGTCCAGCTGGCCGCCCAGACCCTTGCTCACAACGGAGGAAGC CTGCCTCCCGAGCTGCCGCTGTCGCCAGAAGACTCTTTGTCCCCGCCAGCCACGTCCCCTTCTGACTCCGCAGGAACCTCTAGTGCCTCA ACAGACGAAGACATGGAGACAGAGGCCGTCAATGAGATACTGGAAGACATTCCAGAGCATGAGGAAGACTATCTTGACTCAACTCTGGAA >In-frame_PRKAG2_ENST00000492843_chr7_151329155_-_NUB1_ENST00000413040_chr7_151042434_+_2190nt ATGAAGCGCTTTGGGAGCCTCAGGAGCAACAAGAAACACAAGGACCAAAATCGAAGCACGGAGAGGCGCCAGTCGGAGCCTCATGGCCTT TTCGCCTCCGGCCTCTCCTCCTCTCCGTCAACACCCACCCAAGTGACCAAGCAGCACACGTTTCCCCTGGAATCCTATAAGCACGAGCCT GAACGGTTAGAGAATCGCATCTATGCCTCGTCTTCCCCCCCGGACACAGGGCAGAGGTTCTGCCCGTCTTCCTTCCAGAGCCCGACCAGG CCTCCACTGGCATCACCGACACACTATGCTCCCTCCAAAGCCGCGGCGCTGGCGGCGGCCCTGGGACCCGCGGAAGCCGGCATGCTGGAG AAGCTGGAGTTCGAGGACGAAGGGATGGCACAAAAGAAATATCTTCAAGCAAAATTGACCCAGTTTTTAAGGGAAGACAGGATTCAACTT TGGAAACCTCCATATACAGATGAAAATAAAAAAGTTGGTTTGGCATTAAAGGACCTTGCTAAGCAGTACTCTGACAGACTAGAATGCTGT GAAAATGAAGTAGAAAAGGTAATAGAAGAAATACGTTGCAAGGCAATTGAGCGTGGAACAGGAAATGACAATTATAGAACAACGGGAATT GCTACAATCGAGGTGTTTTTACCACCAAGACTAAAAAAAGATAGGAAAAACTTGTTGGAGACCCGATTGCACATCACTGGCAGAGAACTG AGGTCCAAAATAGCTGAAACCTTTGGACTTCAAGAAAATTATATCAAAATTGTCATAAATAAGAAGCAACTACAACTAGGGAAAACCCTT GAAGAACAAGGCGTGGCTCACAATGTGAAAGCGATGGTGCTTGAACTAAAACAATCTGAAGAGGACGCGAGGAAAAACTTCCAGTTAGAG GAAGAGGAGCAAAATGAGGCCAAACTCAAAGAAAAACAAATTCAGAGGACCAAGAGAGGACTAGAAATACTGGCAAAGAGAGCAGCAGAG ACAGTGGTGGATCCAGAAATGACACCGTACTTAGACATAGCTAACCAGACAGGCAGATCAATCAGAATTCCCCCATCAGAAAGAAAAGCC CTTATGTTAGCTATGGGATATCATGAGAAGGGCAGAGCTTTCCTGAAAAGAAAAGAATATGGAATAGCCTTGCCATGTCTGTTGGACGCT GACAAATATTTCTGTGAGTGTTGCAGAGAGCTGCTGGACACAGTGGATAACTACGCCGTCCTCCAGCTGGATATAGTGTGGTGTTACTTC CGCCTGGAACAGCTGGAATGCCTTGATGATGCAGAAAAAAAATTAAACTTGGCCCAGAAATGCTTTAAAAATTGTTACGGAGAAAATCAT CAGAGACTGGTCCACATAAAAGGAAATTGTGGGAAAGAGAAGGTACTGTTTCTAAGACTCTACTTACTTCAAGGGATCCGAAACTATCAC AGTGGAAATGATGTAGAGGCTTATGAGTATCTTAACAAGGCACGTCAGCTCTTTAAAGAGCTATATATTGATCCATCAAAAGTGGACAAT TTGTTGCAGTTGGGGTTTACTGCCCAGGAAGCCCGGCTTGGCCTGAGGGCGTGTGATGGGAACGTGGATCATGCGGCCACTCATATTACC AACCGCAGAGAGGAACTGGCCCAAATAAGGAAGGAGGAAAAAGAGAAGAAAAGACGCCGCCTCGAGAACATCAGGTTTCTGAAAGGGATG GGCTACTCCACGCACGCGGCCCAGCAGATTCTGCTCAGCAATCCTCAGATGTGGTGGTTAAATGATTCCAATCCTGAAACCGACAACCGT CAAGAAAGTCCTTCCCAGGAAAACATTGACCGATTGGTGTACATGGGTTTTGATGCACTCGTGGCCGAAGCTGCGCTGAGAGTGTTCAGA GGCAACGTCCAGCTGGCCGCCCAGACCCTTGCTCACAACGGAGGAAGCCTGCCTCCCGAGCTGCCGCTGTCGCCAGAAGACTCTTTGTCC CCGCCAGCCACGTCCCCTTCTGACTCCGCAGGAACCTCTAGTGCCTCAACAGACGAAGACATGGAGACAGAGGCCGTCAATGAGATACTG GAAGACATTCCAGAGCATGAGGAAGACTATCTTGACTCAACTCTGGAAGATGAAGAAATTATTATTGCAGAGTACCTATCCTATGTAGAA >In-frame_PRKAG2_ENST00000492843_chr7_151329155_-_NUB1_ENST00000568733_chr7_151042434_+_2232nt ATGAAGCGCTTTGGGAGCCTCAGGAGCAACAAGAAACACAAGGACCAAAATCGAAGCACGGAGAGGCGCCAGTCGGAGCCTCATGGCCTT TTCGCCTCCGGCCTCTCCTCCTCTCCGTCAACACCCACCCAAGTGACCAAGCAGCACACGTTTCCCCTGGAATCCTATAAGCACGAGCCT GAACGGTTAGAGAATCGCATCTATGCCTCGTCTTCCCCCCCGGACACAGGGCAGAGGTTCTGCCCGTCTTCCTTCCAGAGCCCGACCAGG CCTCCACTGGCATCACCGACACACTATGCTCCCTCCAAAGCCGCGGCGCTGGCGGCGGCCCTGGGACCCGCGGAAGCCGGCATGCTGGAG AAGCTGGAGTTCGAGGACGAAGGGATGGCACAAAAGAAATATCTTCAAGCAAAATTGACCCAGTTTTTAAGGGAAGACAGGATTCAACTT TGGAAACCTCCATATACAGATGAAAATAAAAAAGTTGGTTTGGCATTAAAGGACCTTGCTAAGCAGTACTCTGACAGACTAGAATGCTGT GAAAATGAAGTAGAAAAGGTAATAGAAGAAATACGTTGCAAGGCAATTGAGCGTGGAACAGGAAATGACAATTATAGAACAACGGGAATT GCTACAATCGAGGTGTTTTTACCACCAAGACTAAAAAAAGATAGGAAAAACTTGTTGGAGACCCGATTGCACATCACTGGCAGAGAACTG AGGTCCAAAATAGCTGAAACCTTTGGACTTCAAGAAAATTATATCAAAATTGTCATAAATAAGAAGCAACTACAACTAGGGAAAACCCTT GAAGAACAAGGCGTGGCTCACAATGTGAAAGCGATGGTGCTTGAACTAAAACAATCTGAAGAGGACGCGAGGAAAAACTTCCAGTTAGAG GAAGAGGAGCAAAATGAGGCCAAACTCAAAGAAAAACAAATTCAGAGGACCAAGAGAGGACTAGAAATACTGGCAAAGAGAGCAGCAGAG ACAGTGGTGGATCCAGAAATGACACCGTACTTAGACATAGCTAACCAGACAGGCAGATCAATCAGAATTCCCCCATCAGAAAGAAAAGCC CTTATGTTAGCTATGGGATATCATGAGAAGGGCAGAGCTTTCCTGAAAAGAAAAGAATATGGAATAGCCTTGCCATGTCTGTTGGACGCT GACAAATATTTCTGTGAGTGTTGCAGAGAGCTGCTGGACACAGTGGATAACTACGCCGTCCTCCAGCTGGATATAGTGTGGTGTTACTTC CGCCTGGAACAGCTGGAATGCCTTGATGATGCAGAAAAAAAATTAAACTTGGCCCAGAAATGCTTTAAAAATTGTTACGGAGAAAATCAT CAGAGACTGGTCCACATAAAAGGAAATTGTGGGAAAGAGAAGGTACTGTTTCTAAGACTCTACTTACTTCAAGGGATCCGAAACTATCAC AGTGGAAATGATGTAGAGGCTTATGAGTATCTTAACAAGGCACGTCAGCTCTTTAAAGAGCTATATATTGATCCATCAAAAGTGGACAAT TTGTTGCAGTTGGGGTTTACTGCCCAGGAAGCCCGGCTTGGCCTGAGGGCGTGTGATGGGAACGTGGATCATGCGGCCACTCATATTACC AACCGCAGAGAGGAACTGGCCCAAATAAGGAAGGAGGAAAAAGAGAAGAAAAGACGCCGCCTCGAGAACATCAGGTTTCTGAAAGGGATG GGCTACTCCACGCACGCGGCCCAGCAGGTACTCCACGCAGCCAGCGGGAACTTGGATGAGGCCCTGAAGATTCTGCTCAGCAATCCTCAG ATGTGGTGGTTAAATGATTCCAATCCTGAAACCGACAACCGTCAAGAAAGTCCTTCCCAGGAAAACATTGACCGATTGGTGTACATGGGT TTTGATGCACTCGTGGCCGAAGCTGCGCTGAGAGTGTTCAGAGGCAACGTCCAGCTGGCCGCCCAGACCCTTGCTCACAACGGAGGAAGC CTGCCTCCCGAGCTGCCGCTGTCGCCAGAAGACTCTTTGTCCCCGCCAGCCACGTCCCCTTCTGACTCCGCAGGAACCTCTAGTGCCTCA ACAGACGAAGACATGGAGACAGAGGCCGTCAATGAGATACTGGAAGACATTCCAGAGCATGAGGAAGACTATCTTGACTCAACTCTGGAA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_PRKAG2_ENST00000287878_chr7_151329155_-_NUB1_ENST00000413040_chr7_151042434_+_4291nt GAGCTGGTTTATTCTGCGGCCGAGGATTACATTTATGCACGAACGGGCTTACTGGTTCCAGATTCCCCACTTGGGCACAGGCATAGGAGG CTTGTTTTCCAAATTGCTGGTTTTAATTGCACCTGCCTTTCAGATTACCTCTGGGAATCTGTGGGAGGAGCCGAGAGGGTGGAAAATGTT TCTTAGCTTTGCAAAAGGAAGAAAACTTTGTCACCCAGCGGGAGACCTCAGCCACGAGTAACCCGGGGAGACACCAGAACCGGGACGGGC TTTGACTGATTTGCCTACGAGGGTTCCGTAGGAAAGGACGCTTGAATTCGGCGCTTCGGCGGCGGCGGCGGCCGCGCGAGTTCCCTGCTC ACCCTCCCTCTCCGCGGAAGTCCCCACGAGGTGGCTTCAGGGTGTAACAGAGCGCGCGGCTCCAGTCCGAAGGCAGCGGCCGGGGGAGGG AAGGAGGGGACCGAACCCCCGAGGAGTTTCGCAGAATCAACTTCTGGTTAGAGTTATGGGAAGCGCGGTTATGGACACCAAGAAGAAAAA AGATGTTTCCAGCCCCGGCGGGAGCGGCGGCAAGAAAAATGCCAGCCAGAAGAGGCGTTCGCTGCGCGTGCACATTCCGGACCTGAGCTC CTTCGCCATGCCGCTCCTGGACGGAGACCTGGAGGGTTCCGGAAAGCATTCCTCTCGAAAGGTGGACAGCCCCTTCGGCCCGGGCAGCCC CTCCAAAGGGTTCTTCTCCAGAGGCCCCCAGCCCCGGCCCTCCAGCCCCATGTCTGCACCTGTGAGGCCCAAGACCAGCCCCGGCTCTCC CAAAACCGTGTTCCCGTTCTCCTACCAGGAGTCCCCGCCACGCTCCCCTCGACGCATGAGCTTCAGTGGGATCTTCCGCTCCTCCTCCAA AGAGTCTTCCCCCAACTCCAACCCTGCTACCTCGCCCGGGGGCATCAGGTTTTTCTCCCGCTCCAGAAAAACCTCCGGCCTCTCCTCCTC TCCGTCAACACCCACCCAAGTGACCAAGCAGCACACGTTTCCCCTGGAATCCTATAAGCACGAGCCTGAACGGTTAGAGAATCGCATCTA TGCCTCGTCTTCCCCCCCGGACACAGGGCAGAGGTTCTGCCCGTCTTCCTTCCAGAGCCCGACCAGGCCTCCACTGGCATCACCGACACA CTATGCTCCCTCCAAAGCCGCGGCGCTGGCGGCGGCCCTGGGACCCGCGGAAGCCGGCATGCTGGAGAAGCTGGAGTTCGAGGACGAAGG GATGGCACAAAAGAAATATCTTCAAGCAAAATTGACCCAGTTTTTAAGGGAAGACAGGATTCAACTTTGGAAACCTCCATATACAGATGA AAATAAAAAAGTTGGTTTGGCATTAAAGGACCTTGCTAAGCAGTACTCTGACAGACTAGAATGCTGTGAAAATGAAGTAGAAAAGGTAAT AGAAGAAATACGTTGCAAGGCAATTGAGCGTGGAACAGGAAATGACAATTATAGAACAACGGGAATTGCTACAATCGAGGTGTTTTTACC ACCAAGACTAAAAAAAGATAGGAAAAACTTGTTGGAGACCCGATTGCACATCACTGGCAGAGAACTGAGGTCCAAAATAGCTGAAACCTT TGGACTTCAAGAAAATTATATCAAAATTGTCATAAATAAGAAGCAACTACAACTAGGGAAAACCCTTGAAGAACAAGGCGTGGCTCACAA TGTGAAAGCGATGGTGCTTGAACTAAAACAATCTGAAGAGGACGCGAGGAAAAACTTCCAGTTAGAGGAAGAGGAGCAAAATGAGGCCAA ACTCAAAGAAAAACAAATTCAGAGGACCAAGAGAGGACTAGAAATACTGGCAAAGAGAGCAGCAGAGACAGTGGTGGATCCAGAAATGAC ACCGTACTTAGACATAGCTAACCAGACAGGCAGATCAATCAGAATTCCCCCATCAGAAAGAAAAGCCCTTATGTTAGCTATGGGATATCA TGAGAAGGGCAGAGCTTTCCTGAAAAGAAAAGAATATGGAATAGCCTTGCCATGTCTGTTGGACGCTGACAAATATTTCTGTGAGTGTTG CAGAGAGCTGCTGGACACAGTGGATAACTACGCCGTCCTCCAGCTGGATATAGTGTGGTGTTACTTCCGCCTGGAACAGCTGGAATGCCT TGATGATGCAGAAAAAAAATTAAACTTGGCCCAGAAATGCTTTAAAAATTGTTACGGAGAAAATCATCAGAGACTGGTCCACATAAAAGG AAATTGTGGGAAAGAGAAGGTACTGTTTCTAAGACTCTACTTACTTCAAGGGATCCGAAACTATCACAGTGGAAATGATGTAGAGGCTTA TGAGTATCTTAACAAGGCACGTCAGCTCTTTAAAGAGCTATATATTGATCCATCAAAAGTGGACAATTTGTTGCAGTTGGGGTTTACTGC CCAGGAAGCCCGGCTTGGCCTGAGGGCGTGTGATGGGAACGTGGATCATGCGGCCACTCATATTACCAACCGCAGAGAGGAACTGGCCCA AATAAGGAAGGAGGAAAAAGAGAAGAAAAGACGCCGCCTCGAGAACATCAGGTTTCTGAAAGGGATGGGCTACTCCACGCACGCGGCCCA GCAGATTCTGCTCAGCAATCCTCAGATGTGGTGGTTAAATGATTCCAATCCTGAAACCGACAACCGTCAAGAAAGTCCTTCCCAGGAAAA CATTGACCGATTGGTGTACATGGGTTTTGATGCACTCGTGGCCGAAGCTGCGCTGAGAGTGTTCAGAGGCAACGTCCAGCTGGCCGCCCA GACCCTTGCTCACAACGGAGGAAGCCTGCCTCCCGAGCTGCCGCTGTCGCCAGAAGACTCTTTGTCCCCGCCAGCCACGTCCCCTTCTGA CTCCGCAGGAACCTCTAGTGCCTCAACAGACGAAGACATGGAGACAGAGGCCGTCAATGAGATACTGGAAGACATTCCAGAGCATGAGGA AGACTATCTTGACTCAACTCTGGAAGATGAAGAAATTATTATTGCAGAGTACCTATCCTATGTAGAAAATAGGAAGTCAGCAACAAAGAA AAACTAAATAATGAACAGAAATAGCGCTAATTTTCTGCTTATAAATGCTATCATTATGAAAAGGCTAATGCAGCTCTTTCTGTTCTTACT TTTTATCTGAATTACAAGTCCTCTTTGGGTGTAGGAGGGGGTGGGCAGGGGACAAGTCCAGGAGGGGTCCCAGGGCCTTCATGCGTGGTC TCGGGGAAGAAGCTTCCTCTGGCCTGGCGCAGGCCGTTCCATCTGCCTCCCAGGTCTGCGTCCCTAACCCCTTCCCCAGCTTGGTGTTTT ACCCCGAAACAGGAAGGAACAGGGGTCCTGTAGAACAGGGGTCCTGGGGAAGGTGTCCAGGGCAGGGTCCTGGGAAGGGTGTCCCGACCG CTTCCTCTCCAGCTGTGGCTCCATCTGCCCAGCTTGCCTGCCTCCTGCACCCACTGCCCTGACCTTCCTGCTTCCCACGCTGCCATCTCT GCCAGGGTGCCACATGGGTTCCTGTGCCACCCTTTCCCCGCCCCTCAAATCGTCCTTTAAGTCTTCCTTCCAAGTGCTGTGGGGCATAAC GATGAGGCGCTGGCCTTGGGGGCCACACCAGGTCGCAGCAAATGGCTTCAGCCTGGGACGCCAGTGTTTTATGCTCTTAGTTCAGTAAAA TACGCCCCCGAAATTCAAGATTGAGTGTCAGGCTTTATATATATTCAGCATTCCTCATTACAGAAATCTTCTATTGAATGGGAAAGGTTT AAATGCTAACCAAAGCAATTTATTTTTAATTAATATTTTTAGACTCTGTGCTGTCATACTGAACTCACTGCTAGCTAAGAGACCTATCAG AGATTTAGATATATTTTCTCCAGGTTTTTTGTGGGTTTTCTTTGTTGTTGTTGTTGTTCTAGCCATGTGACAGAGGCTCTTTCTAAAAGT ATGTAGTTCGCTGTGTGTCGGCTCCAGCAGTAACCGTCCTCACTGCGCCACGCACTCCTCTGTAGATGTGTGCCCAGTGGGAGTTCCTTC CAGCCCCAGGACCACAGCAGCAGCCAGGTGCCGAGTGGATTGAGTGCCAGGTGCATCCAAGACTTTCCCTCCCTTCCAGAAGGCACTGAC TGAAGACAGGATGGATCATGCGGAGCCGGCTGAAATGCTCCAACTTTTTCAAAGTGTGGGTGGTCCAGTTTGGACTGATGGGAATCTTCT >In-frame_PRKAG2_ENST00000287878_chr7_151329155_-_NUB1_ENST00000568733_chr7_151042434_+_4333nt GAGCTGGTTTATTCTGCGGCCGAGGATTACATTTATGCACGAACGGGCTTACTGGTTCCAGATTCCCCACTTGGGCACAGGCATAGGAGG CTTGTTTTCCAAATTGCTGGTTTTAATTGCACCTGCCTTTCAGATTACCTCTGGGAATCTGTGGGAGGAGCCGAGAGGGTGGAAAATGTT TCTTAGCTTTGCAAAAGGAAGAAAACTTTGTCACCCAGCGGGAGACCTCAGCCACGAGTAACCCGGGGAGACACCAGAACCGGGACGGGC TTTGACTGATTTGCCTACGAGGGTTCCGTAGGAAAGGACGCTTGAATTCGGCGCTTCGGCGGCGGCGGCGGCCGCGCGAGTTCCCTGCTC ACCCTCCCTCTCCGCGGAAGTCCCCACGAGGTGGCTTCAGGGTGTAACAGAGCGCGCGGCTCCAGTCCGAAGGCAGCGGCCGGGGGAGGG AAGGAGGGGACCGAACCCCCGAGGAGTTTCGCAGAATCAACTTCTGGTTAGAGTTATGGGAAGCGCGGTTATGGACACCAAGAAGAAAAA AGATGTTTCCAGCCCCGGCGGGAGCGGCGGCAAGAAAAATGCCAGCCAGAAGAGGCGTTCGCTGCGCGTGCACATTCCGGACCTGAGCTC CTTCGCCATGCCGCTCCTGGACGGAGACCTGGAGGGTTCCGGAAAGCATTCCTCTCGAAAGGTGGACAGCCCCTTCGGCCCGGGCAGCCC CTCCAAAGGGTTCTTCTCCAGAGGCCCCCAGCCCCGGCCCTCCAGCCCCATGTCTGCACCTGTGAGGCCCAAGACCAGCCCCGGCTCTCC CAAAACCGTGTTCCCGTTCTCCTACCAGGAGTCCCCGCCACGCTCCCCTCGACGCATGAGCTTCAGTGGGATCTTCCGCTCCTCCTCCAA AGAGTCTTCCCCCAACTCCAACCCTGCTACCTCGCCCGGGGGCATCAGGTTTTTCTCCCGCTCCAGAAAAACCTCCGGCCTCTCCTCCTC TCCGTCAACACCCACCCAAGTGACCAAGCAGCACACGTTTCCCCTGGAATCCTATAAGCACGAGCCTGAACGGTTAGAGAATCGCATCTA TGCCTCGTCTTCCCCCCCGGACACAGGGCAGAGGTTCTGCCCGTCTTCCTTCCAGAGCCCGACCAGGCCTCCACTGGCATCACCGACACA CTATGCTCCCTCCAAAGCCGCGGCGCTGGCGGCGGCCCTGGGACCCGCGGAAGCCGGCATGCTGGAGAAGCTGGAGTTCGAGGACGAAGG GATGGCACAAAAGAAATATCTTCAAGCAAAATTGACCCAGTTTTTAAGGGAAGACAGGATTCAACTTTGGAAACCTCCATATACAGATGA AAATAAAAAAGTTGGTTTGGCATTAAAGGACCTTGCTAAGCAGTACTCTGACAGACTAGAATGCTGTGAAAATGAAGTAGAAAAGGTAAT AGAAGAAATACGTTGCAAGGCAATTGAGCGTGGAACAGGAAATGACAATTATAGAACAACGGGAATTGCTACAATCGAGGTGTTTTTACC ACCAAGACTAAAAAAAGATAGGAAAAACTTGTTGGAGACCCGATTGCACATCACTGGCAGAGAACTGAGGTCCAAAATAGCTGAAACCTT TGGACTTCAAGAAAATTATATCAAAATTGTCATAAATAAGAAGCAACTACAACTAGGGAAAACCCTTGAAGAACAAGGCGTGGCTCACAA TGTGAAAGCGATGGTGCTTGAACTAAAACAATCTGAAGAGGACGCGAGGAAAAACTTCCAGTTAGAGGAAGAGGAGCAAAATGAGGCCAA ACTCAAAGAAAAACAAATTCAGAGGACCAAGAGAGGACTAGAAATACTGGCAAAGAGAGCAGCAGAGACAGTGGTGGATCCAGAAATGAC ACCGTACTTAGACATAGCTAACCAGACAGGCAGATCAATCAGAATTCCCCCATCAGAAAGAAAAGCCCTTATGTTAGCTATGGGATATCA TGAGAAGGGCAGAGCTTTCCTGAAAAGAAAAGAATATGGAATAGCCTTGCCATGTCTGTTGGACGCTGACAAATATTTCTGTGAGTGTTG CAGAGAGCTGCTGGACACAGTGGATAACTACGCCGTCCTCCAGCTGGATATAGTGTGGTGTTACTTCCGCCTGGAACAGCTGGAATGCCT TGATGATGCAGAAAAAAAATTAAACTTGGCCCAGAAATGCTTTAAAAATTGTTACGGAGAAAATCATCAGAGACTGGTCCACATAAAAGG AAATTGTGGGAAAGAGAAGGTACTGTTTCTAAGACTCTACTTACTTCAAGGGATCCGAAACTATCACAGTGGAAATGATGTAGAGGCTTA TGAGTATCTTAACAAGGCACGTCAGCTCTTTAAAGAGCTATATATTGATCCATCAAAAGTGGACAATTTGTTGCAGTTGGGGTTTACTGC CCAGGAAGCCCGGCTTGGCCTGAGGGCGTGTGATGGGAACGTGGATCATGCGGCCACTCATATTACCAACCGCAGAGAGGAACTGGCCCA AATAAGGAAGGAGGAAAAAGAGAAGAAAAGACGCCGCCTCGAGAACATCAGGTTTCTGAAAGGGATGGGCTACTCCACGCACGCGGCCCA GCAGGTACTCCACGCAGCCAGCGGGAACTTGGATGAGGCCCTGAAGATTCTGCTCAGCAATCCTCAGATGTGGTGGTTAAATGATTCCAA TCCTGAAACCGACAACCGTCAAGAAAGTCCTTCCCAGGAAAACATTGACCGATTGGTGTACATGGGTTTTGATGCACTCGTGGCCGAAGC TGCGCTGAGAGTGTTCAGAGGCAACGTCCAGCTGGCCGCCCAGACCCTTGCTCACAACGGAGGAAGCCTGCCTCCCGAGCTGCCGCTGTC GCCAGAAGACTCTTTGTCCCCGCCAGCCACGTCCCCTTCTGACTCCGCAGGAACCTCTAGTGCCTCAACAGACGAAGACATGGAGACAGA GGCCGTCAATGAGATACTGGAAGACATTCCAGAGCATGAGGAAGACTATCTTGACTCAACTCTGGAAGATGAAGAAATTATTATTGCAGA GTACCTATCCTATGTAGAAAATAGGAAGTCAGCAACAAAGAAAAACTAAATAATGAACAGAAATAGCGCTAATTTTCTGCTTATAAATGC TATCATTATGAAAAGGCTAATGCAGCTCTTTCTGTTCTTACTTTTTATCTGAATTACAAGTCCTCTTTGGGTGTAGGAGGGGGTGGGCAG GGGACAAGTCCAGGAGGGGTCCCAGGGCCTTCATGCGTGGTCTCGGGGAAGAAGCTTCCTCTGGCCTGGCGCAGGCCGTTCCATCTGCCT CCCAGGTCTGCGTCCCTAACCCCTTCCCCAGCTTGGTGTTTTACCCCGAAACAGGAAGGAACAGGGGTCCTGTAGAACAGGGGTCCTGGG GAAGGTGTCCAGGGCAGGGTCCTGGGAAGGGTGTCCCGACCGCTTCCTCTCCAGCTGTGGCTCCATCTGCCCAGCTTGCCTGCCTCCTGC ACCCACTGCCCTGACCTTCCTGCTTCCCACGCTGCCATCTCTGCCAGGGTGCCACATGGGTTCCTGTGCCACCCTTTCCCCGCCCCTCAA ATCGTCCTTTAAGTCTTCCTTCCAAGTGCTGTGGGGCATAACGATGAGGCGCTGGCCTTGGGGGCCACACCAGGTCGCAGCAAATGGCTT CAGCCTGGGACGCCAGTGTTTTATGCTCTTAGTTCAGTAAAATACGCCCCCGAAATTCAAGATTGAGTGTCAGGCTTTATATATATTCAG CATTCCTCATTACAGAAATCTTCTATTGAATGGGAAAGGTTTAAATGCTAACCAAAGCAATTTATTTTTAATTAATATTTTTAGACTCTG TGCTGTCATACTGAACTCACTGCTAGCTAAGAGACCTATCAGAGATTTAGATATATTTTCTCCAGGTTTTTTGTGGGTTTTCTTTGTTGT TGTTGTTGTTCTAGCCATGTGACAGAGGCTCTTTCTAAAAGTATGTAGTTCGCTGTGTGTCGGCTCCAGCAGTAACCGTCCTCACTGCGC CACGCACTCCTCTGTAGATGTGTGCCCAGTGGGAGTTCCTTCCAGCCCCAGGACCACAGCAGCAGCCAGGTGCCGAGTGGATTGAGTGCC AGGTGCATCCAAGACTTTCCCTCCCTTCCAGAAGGCACTGACTGAAGACAGGATGGATCATGCGGAGCCGGCTGAAATGCTCCAACTTTT TCAAAGTGTGGGTGGTCCAGTTTGGACTGATGGGAATCTTCTTGTCATTCTTTTTAAACGGATGATACCGATGGAAATAAAAGGTGGGAA >In-frame_PRKAG2_ENST00000433631_chr7_151329155_-_NUB1_ENST00000413040_chr7_151042434_+_3684nt GCTGTGGCCGGAGGTGCAGCCCCGTCAGGACGGCTCCACTCCCTGGCGCCTCACAGACTCTGGGGCTGCGGTGAGGTCGCCCTGAAGACC CCCTGGTGAGGACGCTTGAACCCGGGCTGTCACCTGAGCACAGGCTGCCACTCTGAGCTTTTGGGGCGCCCTGTGCCTGTCGGGCTGATG CTCCTCTGGCTCCCGGCCACCTGGGGCTGACACCGGTTCTGTGGGTCCTGATATGTTCACCTGTCGCCACTCCTGTGGCCACAGCTACCC ATGAAGCGCTTTGGGAGCCTCAGGAGCAACAAGAAACACAAGGACCAAAATCGAAGCACGGAGAGGCGCCAGTCGGAGCCTCATGGCCTT TTCGCCTCCGGCCTCTCCTCCTCTCCGTCAACACCCACCCAAGTGACCAAGCAGCACACGTTTCCCCTGGAATCCTATAAGCACGAGCCT GAACGGTTAGAGAATCGCATCTATGCCTCGTCTTCCCCCCCGGACACAGGGCAGAGGTTCTGCCCGTCTTCCTTCCAGAGCCCGACCAGG CCTCCACTGGCATCACCGACACACTATGCTCCCTCCAAAGCCGCGGCGCTGGCGGCGGCCCTGGGACCCGCGGAAGCCGGCATGCTGGAG AAGCTGGAGTTCGAGGACGAAGGGATGGCACAAAAGAAATATCTTCAAGCAAAATTGACCCAGTTTTTAAGGGAAGACAGGATTCAACTT TGGAAACCTCCATATACAGATGAAAATAAAAAAGTTGGTTTGGCATTAAAGGACCTTGCTAAGCAGTACTCTGACAGACTAGAATGCTGT GAAAATGAAGTAGAAAAGGTAATAGAAGAAATACGTTGCAAGGCAATTGAGCGTGGAACAGGAAATGACAATTATAGAACAACGGGAATT GCTACAATCGAGGTGTTTTTACCACCAAGACTAAAAAAAGATAGGAAAAACTTGTTGGAGACCCGATTGCACATCACTGGCAGAGAACTG AGGTCCAAAATAGCTGAAACCTTTGGACTTCAAGAAAATTATATCAAAATTGTCATAAATAAGAAGCAACTACAACTAGGGAAAACCCTT GAAGAACAAGGCGTGGCTCACAATGTGAAAGCGATGGTGCTTGAACTAAAACAATCTGAAGAGGACGCGAGGAAAAACTTCCAGTTAGAG GAAGAGGAGCAAAATGAGGCCAAACTCAAAGAAAAACAAATTCAGAGGACCAAGAGAGGACTAGAAATACTGGCAAAGAGAGCAGCAGAG ACAGTGGTGGATCCAGAAATGACACCGTACTTAGACATAGCTAACCAGACAGGCAGATCAATCAGAATTCCCCCATCAGAAAGAAAAGCC CTTATGTTAGCTATGGGATATCATGAGAAGGGCAGAGCTTTCCTGAAAAGAAAAGAATATGGAATAGCCTTGCCATGTCTGTTGGACGCT GACAAATATTTCTGTGAGTGTTGCAGAGAGCTGCTGGACACAGTGGATAACTACGCCGTCCTCCAGCTGGATATAGTGTGGTGTTACTTC CGCCTGGAACAGCTGGAATGCCTTGATGATGCAGAAAAAAAATTAAACTTGGCCCAGAAATGCTTTAAAAATTGTTACGGAGAAAATCAT CAGAGACTGGTCCACATAAAAGGAAATTGTGGGAAAGAGAAGGTACTGTTTCTAAGACTCTACTTACTTCAAGGGATCCGAAACTATCAC AGTGGAAATGATGTAGAGGCTTATGAGTATCTTAACAAGGCACGTCAGCTCTTTAAAGAGCTATATATTGATCCATCAAAAGTGGACAAT TTGTTGCAGTTGGGGTTTACTGCCCAGGAAGCCCGGCTTGGCCTGAGGGCGTGTGATGGGAACGTGGATCATGCGGCCACTCATATTACC AACCGCAGAGAGGAACTGGCCCAAATAAGGAAGGAGGAAAAAGAGAAGAAAAGACGCCGCCTCGAGAACATCAGGTTTCTGAAAGGGATG GGCTACTCCACGCACGCGGCCCAGCAGATTCTGCTCAGCAATCCTCAGATGTGGTGGTTAAATGATTCCAATCCTGAAACCGACAACCGT CAAGAAAGTCCTTCCCAGGAAAACATTGACCGATTGGTGTACATGGGTTTTGATGCACTCGTGGCCGAAGCTGCGCTGAGAGTGTTCAGA GGCAACGTCCAGCTGGCCGCCCAGACCCTTGCTCACAACGGAGGAAGCCTGCCTCCCGAGCTGCCGCTGTCGCCAGAAGACTCTTTGTCC CCGCCAGCCACGTCCCCTTCTGACTCCGCAGGAACCTCTAGTGCCTCAACAGACGAAGACATGGAGACAGAGGCCGTCAATGAGATACTG GAAGACATTCCAGAGCATGAGGAAGACTATCTTGACTCAACTCTGGAAGATGAAGAAATTATTATTGCAGAGTACCTATCCTATGTAGAA AATAGGAAGTCAGCAACAAAGAAAAACTAAATAATGAACAGAAATAGCGCTAATTTTCTGCTTATAAATGCTATCATTATGAAAAGGCTA ATGCAGCTCTTTCTGTTCTTACTTTTTATCTGAATTACAAGTCCTCTTTGGGTGTAGGAGGGGGTGGGCAGGGGACAAGTCCAGGAGGGG TCCCAGGGCCTTCATGCGTGGTCTCGGGGAAGAAGCTTCCTCTGGCCTGGCGCAGGCCGTTCCATCTGCCTCCCAGGTCTGCGTCCCTAA CCCCTTCCCCAGCTTGGTGTTTTACCCCGAAACAGGAAGGAACAGGGGTCCTGTAGAACAGGGGTCCTGGGGAAGGTGTCCAGGGCAGGG TCCTGGGAAGGGTGTCCCGACCGCTTCCTCTCCAGCTGTGGCTCCATCTGCCCAGCTTGCCTGCCTCCTGCACCCACTGCCCTGACCTTC CTGCTTCCCACGCTGCCATCTCTGCCAGGGTGCCACATGGGTTCCTGTGCCACCCTTTCCCCGCCCCTCAAATCGTCCTTTAAGTCTTCC TTCCAAGTGCTGTGGGGCATAACGATGAGGCGCTGGCCTTGGGGGCCACACCAGGTCGCAGCAAATGGCTTCAGCCTGGGACGCCAGTGT TTTATGCTCTTAGTTCAGTAAAATACGCCCCCGAAATTCAAGATTGAGTGTCAGGCTTTATATATATTCAGCATTCCTCATTACAGAAAT CTTCTATTGAATGGGAAAGGTTTAAATGCTAACCAAAGCAATTTATTTTTAATTAATATTTTTAGACTCTGTGCTGTCATACTGAACTCA CTGCTAGCTAAGAGACCTATCAGAGATTTAGATATATTTTCTCCAGGTTTTTTGTGGGTTTTCTTTGTTGTTGTTGTTGTTCTAGCCATG TGACAGAGGCTCTTTCTAAAAGTATGTAGTTCGCTGTGTGTCGGCTCCAGCAGTAACCGTCCTCACTGCGCCACGCACTCCTCTGTAGAT GTGTGCCCAGTGGGAGTTCCTTCCAGCCCCAGGACCACAGCAGCAGCCAGGTGCCGAGTGGATTGAGTGCCAGGTGCATCCAAGACTTTC CCTCCCTTCCAGAAGGCACTGACTGAAGACAGGATGGATCATGCGGAGCCGGCTGAAATGCTCCAACTTTTTCAAAGTGTGGGTGGTCCA >In-frame_PRKAG2_ENST00000433631_chr7_151329155_-_NUB1_ENST00000568733_chr7_151042434_+_3726nt GCTGTGGCCGGAGGTGCAGCCCCGTCAGGACGGCTCCACTCCCTGGCGCCTCACAGACTCTGGGGCTGCGGTGAGGTCGCCCTGAAGACC CCCTGGTGAGGACGCTTGAACCCGGGCTGTCACCTGAGCACAGGCTGCCACTCTGAGCTTTTGGGGCGCCCTGTGCCTGTCGGGCTGATG CTCCTCTGGCTCCCGGCCACCTGGGGCTGACACCGGTTCTGTGGGTCCTGATATGTTCACCTGTCGCCACTCCTGTGGCCACAGCTACCC ATGAAGCGCTTTGGGAGCCTCAGGAGCAACAAGAAACACAAGGACCAAAATCGAAGCACGGAGAGGCGCCAGTCGGAGCCTCATGGCCTT TTCGCCTCCGGCCTCTCCTCCTCTCCGTCAACACCCACCCAAGTGACCAAGCAGCACACGTTTCCCCTGGAATCCTATAAGCACGAGCCT GAACGGTTAGAGAATCGCATCTATGCCTCGTCTTCCCCCCCGGACACAGGGCAGAGGTTCTGCCCGTCTTCCTTCCAGAGCCCGACCAGG CCTCCACTGGCATCACCGACACACTATGCTCCCTCCAAAGCCGCGGCGCTGGCGGCGGCCCTGGGACCCGCGGAAGCCGGCATGCTGGAG AAGCTGGAGTTCGAGGACGAAGGGATGGCACAAAAGAAATATCTTCAAGCAAAATTGACCCAGTTTTTAAGGGAAGACAGGATTCAACTT TGGAAACCTCCATATACAGATGAAAATAAAAAAGTTGGTTTGGCATTAAAGGACCTTGCTAAGCAGTACTCTGACAGACTAGAATGCTGT GAAAATGAAGTAGAAAAGGTAATAGAAGAAATACGTTGCAAGGCAATTGAGCGTGGAACAGGAAATGACAATTATAGAACAACGGGAATT GCTACAATCGAGGTGTTTTTACCACCAAGACTAAAAAAAGATAGGAAAAACTTGTTGGAGACCCGATTGCACATCACTGGCAGAGAACTG AGGTCCAAAATAGCTGAAACCTTTGGACTTCAAGAAAATTATATCAAAATTGTCATAAATAAGAAGCAACTACAACTAGGGAAAACCCTT GAAGAACAAGGCGTGGCTCACAATGTGAAAGCGATGGTGCTTGAACTAAAACAATCTGAAGAGGACGCGAGGAAAAACTTCCAGTTAGAG GAAGAGGAGCAAAATGAGGCCAAACTCAAAGAAAAACAAATTCAGAGGACCAAGAGAGGACTAGAAATACTGGCAAAGAGAGCAGCAGAG ACAGTGGTGGATCCAGAAATGACACCGTACTTAGACATAGCTAACCAGACAGGCAGATCAATCAGAATTCCCCCATCAGAAAGAAAAGCC CTTATGTTAGCTATGGGATATCATGAGAAGGGCAGAGCTTTCCTGAAAAGAAAAGAATATGGAATAGCCTTGCCATGTCTGTTGGACGCT GACAAATATTTCTGTGAGTGTTGCAGAGAGCTGCTGGACACAGTGGATAACTACGCCGTCCTCCAGCTGGATATAGTGTGGTGTTACTTC CGCCTGGAACAGCTGGAATGCCTTGATGATGCAGAAAAAAAATTAAACTTGGCCCAGAAATGCTTTAAAAATTGTTACGGAGAAAATCAT CAGAGACTGGTCCACATAAAAGGAAATTGTGGGAAAGAGAAGGTACTGTTTCTAAGACTCTACTTACTTCAAGGGATCCGAAACTATCAC AGTGGAAATGATGTAGAGGCTTATGAGTATCTTAACAAGGCACGTCAGCTCTTTAAAGAGCTATATATTGATCCATCAAAAGTGGACAAT TTGTTGCAGTTGGGGTTTACTGCCCAGGAAGCCCGGCTTGGCCTGAGGGCGTGTGATGGGAACGTGGATCATGCGGCCACTCATATTACC AACCGCAGAGAGGAACTGGCCCAAATAAGGAAGGAGGAAAAAGAGAAGAAAAGACGCCGCCTCGAGAACATCAGGTTTCTGAAAGGGATG GGCTACTCCACGCACGCGGCCCAGCAGGTACTCCACGCAGCCAGCGGGAACTTGGATGAGGCCCTGAAGATTCTGCTCAGCAATCCTCAG ATGTGGTGGTTAAATGATTCCAATCCTGAAACCGACAACCGTCAAGAAAGTCCTTCCCAGGAAAACATTGACCGATTGGTGTACATGGGT TTTGATGCACTCGTGGCCGAAGCTGCGCTGAGAGTGTTCAGAGGCAACGTCCAGCTGGCCGCCCAGACCCTTGCTCACAACGGAGGAAGC CTGCCTCCCGAGCTGCCGCTGTCGCCAGAAGACTCTTTGTCCCCGCCAGCCACGTCCCCTTCTGACTCCGCAGGAACCTCTAGTGCCTCA ACAGACGAAGACATGGAGACAGAGGCCGTCAATGAGATACTGGAAGACATTCCAGAGCATGAGGAAGACTATCTTGACTCAACTCTGGAA GATGAAGAAATTATTATTGCAGAGTACCTATCCTATGTAGAAAATAGGAAGTCAGCAACAAAGAAAAACTAAATAATGAACAGAAATAGC GCTAATTTTCTGCTTATAAATGCTATCATTATGAAAAGGCTAATGCAGCTCTTTCTGTTCTTACTTTTTATCTGAATTACAAGTCCTCTT TGGGTGTAGGAGGGGGTGGGCAGGGGACAAGTCCAGGAGGGGTCCCAGGGCCTTCATGCGTGGTCTCGGGGAAGAAGCTTCCTCTGGCCT GGCGCAGGCCGTTCCATCTGCCTCCCAGGTCTGCGTCCCTAACCCCTTCCCCAGCTTGGTGTTTTACCCCGAAACAGGAAGGAACAGGGG TCCTGTAGAACAGGGGTCCTGGGGAAGGTGTCCAGGGCAGGGTCCTGGGAAGGGTGTCCCGACCGCTTCCTCTCCAGCTGTGGCTCCATC TGCCCAGCTTGCCTGCCTCCTGCACCCACTGCCCTGACCTTCCTGCTTCCCACGCTGCCATCTCTGCCAGGGTGCCACATGGGTTCCTGT GCCACCCTTTCCCCGCCCCTCAAATCGTCCTTTAAGTCTTCCTTCCAAGTGCTGTGGGGCATAACGATGAGGCGCTGGCCTTGGGGGCCA CACCAGGTCGCAGCAAATGGCTTCAGCCTGGGACGCCAGTGTTTTATGCTCTTAGTTCAGTAAAATACGCCCCCGAAATTCAAGATTGAG TGTCAGGCTTTATATATATTCAGCATTCCTCATTACAGAAATCTTCTATTGAATGGGAAAGGTTTAAATGCTAACCAAAGCAATTTATTT TTAATTAATATTTTTAGACTCTGTGCTGTCATACTGAACTCACTGCTAGCTAAGAGACCTATCAGAGATTTAGATATATTTTCTCCAGGT TTTTTGTGGGTTTTCTTTGTTGTTGTTGTTGTTCTAGCCATGTGACAGAGGCTCTTTCTAAAAGTATGTAGTTCGCTGTGTGTCGGCTCC AGCAGTAACCGTCCTCACTGCGCCACGCACTCCTCTGTAGATGTGTGCCCAGTGGGAGTTCCTTCCAGCCCCAGGACCACAGCAGCAGCC AGGTGCCGAGTGGATTGAGTGCCAGGTGCATCCAAGACTTTCCCTCCCTTCCAGAAGGCACTGACTGAAGACAGGATGGATCATGCGGAG CCGGCTGAAATGCTCCAACTTTTTCAAAGTGTGGGTGGTCCAGTTTGGACTGATGGGAATCTTCTTGTCATTCTTTTTAAACGGATGATA >In-frame_PRKAG2_ENST00000492843_chr7_151329155_-_NUB1_ENST00000413040_chr7_151042434_+_3735nt GCTTCCGGCAGCTTCTTGCTACTTAAGGACAGCCGGGCTGACGCTCCAGCTGCTGTGGCCGGAGGTGCAGCCCCGTCAGGACGGCTCCAC TCCCTGGCGCCTCACAGACTCTGGGGCTGCGGTGAGGTCGCCCTGAAGACCCCCTGGTGAGGACGCTTGAACCCGGGCTGTCACCTGAGC ACAGGCTGCCACTCTGAGCTTTTGGGGCGCCCTGTGCCTGTCGGGCTGATGCTCCTCTGGCTCCCGGCCACCTGGGGCTGACACCGGTTC TGTGGGTCCTGATATGTTCACCTGTCGCCACTCCTGTGGCCACAGCTACCCATGAAGCGCTTTGGGAGCCTCAGGAGCAACAAGAAACAC AAGGACCAAAATCGAAGCACGGAGAGGCGCCAGTCGGAGCCTCATGGCCTTTTCGCCTCCGGCCTCTCCTCCTCTCCGTCAACACCCACC CAAGTGACCAAGCAGCACACGTTTCCCCTGGAATCCTATAAGCACGAGCCTGAACGGTTAGAGAATCGCATCTATGCCTCGTCTTCCCCC CCGGACACAGGGCAGAGGTTCTGCCCGTCTTCCTTCCAGAGCCCGACCAGGCCTCCACTGGCATCACCGACACACTATGCTCCCTCCAAA GCCGCGGCGCTGGCGGCGGCCCTGGGACCCGCGGAAGCCGGCATGCTGGAGAAGCTGGAGTTCGAGGACGAAGGGATGGCACAAAAGAAA TATCTTCAAGCAAAATTGACCCAGTTTTTAAGGGAAGACAGGATTCAACTTTGGAAACCTCCATATACAGATGAAAATAAAAAAGTTGGT TTGGCATTAAAGGACCTTGCTAAGCAGTACTCTGACAGACTAGAATGCTGTGAAAATGAAGTAGAAAAGGTAATAGAAGAAATACGTTGC AAGGCAATTGAGCGTGGAACAGGAAATGACAATTATAGAACAACGGGAATTGCTACAATCGAGGTGTTTTTACCACCAAGACTAAAAAAA GATAGGAAAAACTTGTTGGAGACCCGATTGCACATCACTGGCAGAGAACTGAGGTCCAAAATAGCTGAAACCTTTGGACTTCAAGAAAAT TATATCAAAATTGTCATAAATAAGAAGCAACTACAACTAGGGAAAACCCTTGAAGAACAAGGCGTGGCTCACAATGTGAAAGCGATGGTG CTTGAACTAAAACAATCTGAAGAGGACGCGAGGAAAAACTTCCAGTTAGAGGAAGAGGAGCAAAATGAGGCCAAACTCAAAGAAAAACAA ATTCAGAGGACCAAGAGAGGACTAGAAATACTGGCAAAGAGAGCAGCAGAGACAGTGGTGGATCCAGAAATGACACCGTACTTAGACATA GCTAACCAGACAGGCAGATCAATCAGAATTCCCCCATCAGAAAGAAAAGCCCTTATGTTAGCTATGGGATATCATGAGAAGGGCAGAGCT TTCCTGAAAAGAAAAGAATATGGAATAGCCTTGCCATGTCTGTTGGACGCTGACAAATATTTCTGTGAGTGTTGCAGAGAGCTGCTGGAC ACAGTGGATAACTACGCCGTCCTCCAGCTGGATATAGTGTGGTGTTACTTCCGCCTGGAACAGCTGGAATGCCTTGATGATGCAGAAAAA AAATTAAACTTGGCCCAGAAATGCTTTAAAAATTGTTACGGAGAAAATCATCAGAGACTGGTCCACATAAAAGGAAATTGTGGGAAAGAG AAGGTACTGTTTCTAAGACTCTACTTACTTCAAGGGATCCGAAACTATCACAGTGGAAATGATGTAGAGGCTTATGAGTATCTTAACAAG GCACGTCAGCTCTTTAAAGAGCTATATATTGATCCATCAAAAGTGGACAATTTGTTGCAGTTGGGGTTTACTGCCCAGGAAGCCCGGCTT GGCCTGAGGGCGTGTGATGGGAACGTGGATCATGCGGCCACTCATATTACCAACCGCAGAGAGGAACTGGCCCAAATAAGGAAGGAGGAA AAAGAGAAGAAAAGACGCCGCCTCGAGAACATCAGGTTTCTGAAAGGGATGGGCTACTCCACGCACGCGGCCCAGCAGATTCTGCTCAGC AATCCTCAGATGTGGTGGTTAAATGATTCCAATCCTGAAACCGACAACCGTCAAGAAAGTCCTTCCCAGGAAAACATTGACCGATTGGTG TACATGGGTTTTGATGCACTCGTGGCCGAAGCTGCGCTGAGAGTGTTCAGAGGCAACGTCCAGCTGGCCGCCCAGACCCTTGCTCACAAC GGAGGAAGCCTGCCTCCCGAGCTGCCGCTGTCGCCAGAAGACTCTTTGTCCCCGCCAGCCACGTCCCCTTCTGACTCCGCAGGAACCTCT AGTGCCTCAACAGACGAAGACATGGAGACAGAGGCCGTCAATGAGATACTGGAAGACATTCCAGAGCATGAGGAAGACTATCTTGACTCA ACTCTGGAAGATGAAGAAATTATTATTGCAGAGTACCTATCCTATGTAGAAAATAGGAAGTCAGCAACAAAGAAAAACTAAATAATGAAC AGAAATAGCGCTAATTTTCTGCTTATAAATGCTATCATTATGAAAAGGCTAATGCAGCTCTTTCTGTTCTTACTTTTTATCTGAATTACA AGTCCTCTTTGGGTGTAGGAGGGGGTGGGCAGGGGACAAGTCCAGGAGGGGTCCCAGGGCCTTCATGCGTGGTCTCGGGGAAGAAGCTTC CTCTGGCCTGGCGCAGGCCGTTCCATCTGCCTCCCAGGTCTGCGTCCCTAACCCCTTCCCCAGCTTGGTGTTTTACCCCGAAACAGGAAG GAACAGGGGTCCTGTAGAACAGGGGTCCTGGGGAAGGTGTCCAGGGCAGGGTCCTGGGAAGGGTGTCCCGACCGCTTCCTCTCCAGCTGT GGCTCCATCTGCCCAGCTTGCCTGCCTCCTGCACCCACTGCCCTGACCTTCCTGCTTCCCACGCTGCCATCTCTGCCAGGGTGCCACATG GGTTCCTGTGCCACCCTTTCCCCGCCCCTCAAATCGTCCTTTAAGTCTTCCTTCCAAGTGCTGTGGGGCATAACGATGAGGCGCTGGCCT TGGGGGCCACACCAGGTCGCAGCAAATGGCTTCAGCCTGGGACGCCAGTGTTTTATGCTCTTAGTTCAGTAAAATACGCCCCCGAAATTC AAGATTGAGTGTCAGGCTTTATATATATTCAGCATTCCTCATTACAGAAATCTTCTATTGAATGGGAAAGGTTTAAATGCTAACCAAAGC AATTTATTTTTAATTAATATTTTTAGACTCTGTGCTGTCATACTGAACTCACTGCTAGCTAAGAGACCTATCAGAGATTTAGATATATTT TCTCCAGGTTTTTTGTGGGTTTTCTTTGTTGTTGTTGTTGTTCTAGCCATGTGACAGAGGCTCTTTCTAAAAGTATGTAGTTCGCTGTGT GTCGGCTCCAGCAGTAACCGTCCTCACTGCGCCACGCACTCCTCTGTAGATGTGTGCCCAGTGGGAGTTCCTTCCAGCCCCAGGACCACA GCAGCAGCCAGGTGCCGAGTGGATTGAGTGCCAGGTGCATCCAAGACTTTCCCTCCCTTCCAGAAGGCACTGACTGAAGACAGGATGGAT CATGCGGAGCCGGCTGAAATGCTCCAACTTTTTCAAAGTGTGGGTGGTCCAGTTTGGACTGATGGGAATCTTCTTGTCATTCTTTTTAAA >In-frame_PRKAG2_ENST00000492843_chr7_151329155_-_NUB1_ENST00000568733_chr7_151042434_+_3777nt GCTTCCGGCAGCTTCTTGCTACTTAAGGACAGCCGGGCTGACGCTCCAGCTGCTGTGGCCGGAGGTGCAGCCCCGTCAGGACGGCTCCAC TCCCTGGCGCCTCACAGACTCTGGGGCTGCGGTGAGGTCGCCCTGAAGACCCCCTGGTGAGGACGCTTGAACCCGGGCTGTCACCTGAGC ACAGGCTGCCACTCTGAGCTTTTGGGGCGCCCTGTGCCTGTCGGGCTGATGCTCCTCTGGCTCCCGGCCACCTGGGGCTGACACCGGTTC TGTGGGTCCTGATATGTTCACCTGTCGCCACTCCTGTGGCCACAGCTACCCATGAAGCGCTTTGGGAGCCTCAGGAGCAACAAGAAACAC AAGGACCAAAATCGAAGCACGGAGAGGCGCCAGTCGGAGCCTCATGGCCTTTTCGCCTCCGGCCTCTCCTCCTCTCCGTCAACACCCACC CAAGTGACCAAGCAGCACACGTTTCCCCTGGAATCCTATAAGCACGAGCCTGAACGGTTAGAGAATCGCATCTATGCCTCGTCTTCCCCC CCGGACACAGGGCAGAGGTTCTGCCCGTCTTCCTTCCAGAGCCCGACCAGGCCTCCACTGGCATCACCGACACACTATGCTCCCTCCAAA GCCGCGGCGCTGGCGGCGGCCCTGGGACCCGCGGAAGCCGGCATGCTGGAGAAGCTGGAGTTCGAGGACGAAGGGATGGCACAAAAGAAA TATCTTCAAGCAAAATTGACCCAGTTTTTAAGGGAAGACAGGATTCAACTTTGGAAACCTCCATATACAGATGAAAATAAAAAAGTTGGT TTGGCATTAAAGGACCTTGCTAAGCAGTACTCTGACAGACTAGAATGCTGTGAAAATGAAGTAGAAAAGGTAATAGAAGAAATACGTTGC AAGGCAATTGAGCGTGGAACAGGAAATGACAATTATAGAACAACGGGAATTGCTACAATCGAGGTGTTTTTACCACCAAGACTAAAAAAA GATAGGAAAAACTTGTTGGAGACCCGATTGCACATCACTGGCAGAGAACTGAGGTCCAAAATAGCTGAAACCTTTGGACTTCAAGAAAAT TATATCAAAATTGTCATAAATAAGAAGCAACTACAACTAGGGAAAACCCTTGAAGAACAAGGCGTGGCTCACAATGTGAAAGCGATGGTG CTTGAACTAAAACAATCTGAAGAGGACGCGAGGAAAAACTTCCAGTTAGAGGAAGAGGAGCAAAATGAGGCCAAACTCAAAGAAAAACAA ATTCAGAGGACCAAGAGAGGACTAGAAATACTGGCAAAGAGAGCAGCAGAGACAGTGGTGGATCCAGAAATGACACCGTACTTAGACATA GCTAACCAGACAGGCAGATCAATCAGAATTCCCCCATCAGAAAGAAAAGCCCTTATGTTAGCTATGGGATATCATGAGAAGGGCAGAGCT TTCCTGAAAAGAAAAGAATATGGAATAGCCTTGCCATGTCTGTTGGACGCTGACAAATATTTCTGTGAGTGTTGCAGAGAGCTGCTGGAC ACAGTGGATAACTACGCCGTCCTCCAGCTGGATATAGTGTGGTGTTACTTCCGCCTGGAACAGCTGGAATGCCTTGATGATGCAGAAAAA AAATTAAACTTGGCCCAGAAATGCTTTAAAAATTGTTACGGAGAAAATCATCAGAGACTGGTCCACATAAAAGGAAATTGTGGGAAAGAG AAGGTACTGTTTCTAAGACTCTACTTACTTCAAGGGATCCGAAACTATCACAGTGGAAATGATGTAGAGGCTTATGAGTATCTTAACAAG GCACGTCAGCTCTTTAAAGAGCTATATATTGATCCATCAAAAGTGGACAATTTGTTGCAGTTGGGGTTTACTGCCCAGGAAGCCCGGCTT GGCCTGAGGGCGTGTGATGGGAACGTGGATCATGCGGCCACTCATATTACCAACCGCAGAGAGGAACTGGCCCAAATAAGGAAGGAGGAA AAAGAGAAGAAAAGACGCCGCCTCGAGAACATCAGGTTTCTGAAAGGGATGGGCTACTCCACGCACGCGGCCCAGCAGGTACTCCACGCA GCCAGCGGGAACTTGGATGAGGCCCTGAAGATTCTGCTCAGCAATCCTCAGATGTGGTGGTTAAATGATTCCAATCCTGAAACCGACAAC CGTCAAGAAAGTCCTTCCCAGGAAAACATTGACCGATTGGTGTACATGGGTTTTGATGCACTCGTGGCCGAAGCTGCGCTGAGAGTGTTC AGAGGCAACGTCCAGCTGGCCGCCCAGACCCTTGCTCACAACGGAGGAAGCCTGCCTCCCGAGCTGCCGCTGTCGCCAGAAGACTCTTTG TCCCCGCCAGCCACGTCCCCTTCTGACTCCGCAGGAACCTCTAGTGCCTCAACAGACGAAGACATGGAGACAGAGGCCGTCAATGAGATA CTGGAAGACATTCCAGAGCATGAGGAAGACTATCTTGACTCAACTCTGGAAGATGAAGAAATTATTATTGCAGAGTACCTATCCTATGTA GAAAATAGGAAGTCAGCAACAAAGAAAAACTAAATAATGAACAGAAATAGCGCTAATTTTCTGCTTATAAATGCTATCATTATGAAAAGG CTAATGCAGCTCTTTCTGTTCTTACTTTTTATCTGAATTACAAGTCCTCTTTGGGTGTAGGAGGGGGTGGGCAGGGGACAAGTCCAGGAG GGGTCCCAGGGCCTTCATGCGTGGTCTCGGGGAAGAAGCTTCCTCTGGCCTGGCGCAGGCCGTTCCATCTGCCTCCCAGGTCTGCGTCCC TAACCCCTTCCCCAGCTTGGTGTTTTACCCCGAAACAGGAAGGAACAGGGGTCCTGTAGAACAGGGGTCCTGGGGAAGGTGTCCAGGGCA GGGTCCTGGGAAGGGTGTCCCGACCGCTTCCTCTCCAGCTGTGGCTCCATCTGCCCAGCTTGCCTGCCTCCTGCACCCACTGCCCTGACC TTCCTGCTTCCCACGCTGCCATCTCTGCCAGGGTGCCACATGGGTTCCTGTGCCACCCTTTCCCCGCCCCTCAAATCGTCCTTTAAGTCT TCCTTCCAAGTGCTGTGGGGCATAACGATGAGGCGCTGGCCTTGGGGGCCACACCAGGTCGCAGCAAATGGCTTCAGCCTGGGACGCCAG TGTTTTATGCTCTTAGTTCAGTAAAATACGCCCCCGAAATTCAAGATTGAGTGTCAGGCTTTATATATATTCAGCATTCCTCATTACAGA AATCTTCTATTGAATGGGAAAGGTTTAAATGCTAACCAAAGCAATTTATTTTTAATTAATATTTTTAGACTCTGTGCTGTCATACTGAAC TCACTGCTAGCTAAGAGACCTATCAGAGATTTAGATATATTTTCTCCAGGTTTTTTGTGGGTTTTCTTTGTTGTTGTTGTTGTTCTAGCC ATGTGACAGAGGCTCTTTCTAAAAGTATGTAGTTCGCTGTGTGTCGGCTCCAGCAGTAACCGTCCTCACTGCGCCACGCACTCCTCTGTA GATGTGTGCCCAGTGGGAGTTCCTTCCAGCCCCAGGACCACAGCAGCAGCCAGGTGCCGAGTGGATTGAGTGCCAGGTGCATCCAAGACT TTCCCTCCCTTCCAGAAGGCACTGACTGAAGACAGGATGGATCATGCGGAGCCGGCTGAAATGCTCCAACTTTTTCAAAGTGTGGGTGGT |
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FusionGenePPI for PRKAG2_NUB1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| PRKAG2 | PRKAB1, PRKAB2, PRKAG1, PRKAA2, PRKAA1, MAP1B, MAP1LC3A, PGK1, PFAS, FKBP4, EIF3A, TARS, GMPS, GANAB, MAP1A, ASNS, ELAVL1, WDR83, DCLRE1C, NF2, STIM2, GEMIN2, PHKG2, NEFH | NUB1 | FANCA, UBD, NEDD8, PSMD4, AIPL1, TP53, PSMD2, FAT1, PSMB4, SNCAIP, UBE2K, HSPA4, MAPT, GSK3B, ECT2, COPB1, VCP, UFD1L, SHFM1, SF3B4, UBC, RNF168, TERF1, VAV1, TRIM25 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for PRKAG2_NUB1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for PRKAG2_NUB1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | PRKAG2 | C0043202 | Wolff-Parkinson-White Syndrome | 4 | CTD_human;HPO;UNIPROT |
| Hgene | PRKAG2 | C1833236 | CARDIOMYOPATHY, FAMILIAL HYPERTROPHIC, 6 (disorder) | 3 | CTD_human;UNIPROT |
| Hgene | PRKAG2 | C1849813 | Glycogen Storage Disease of Heart, Lethal Congenital | 1 | CTD_human;ORPHANET;UNIPROT |
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