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Fusion gene ID: 28469 |
FusionGeneSummary for PPP3CA_COL25A1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PPP3CA_COL25A1 | Fusion gene ID: 28469 | Hgene | Tgene | Gene symbol | PPP3CA | COL25A1 | Gene ID | 5530 | 84570 |
| Gene name | protein phosphatase 3 catalytic subunit alpha | collagen type XXV alpha 1 chain | |
| Synonyms | CALN|CALNA|CALNA1|CCN1|CNA1|IECEE|IECEE1|PPP2B | AMY|CFEOM5|CLAC|CLAC-P|CLACP | |
| Cytomap | 4q24 | 4q25 | |
| Type of gene | protein-coding | protein-coding | |
| Description | serine/threonine-protein phosphatase 2B catalytic subunit alpha isoformCAM-PRP catalytic subunitcalcineurin A alphacalmodulin-dependent calcineurin A subunit alpha isoformprotein phosphatase 2B, catalytic subunit, alpha isoformprotein phosphatase 3 ( | collagen alpha-1(XXV) chainalzheimer disease amyloid-associated proteincollagen-like Alzheimer amyloid plaque componentcollagenous Alzheimer amyloid plaque component | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q08209 | Q9BXS0 | |
| Ensembl transtripts involved in fusion gene | ENST00000512215, ENST00000394854, ENST00000323055, ENST00000394853, ENST00000507176, ENST00000523694, ENST00000510292, | ENST00000399132, ENST00000399127, ENST00000399126, | |
| Fusion gene scores | * DoF score | 11 X 7 X 5=385 | 3 X 3 X 3=27 |
| # samples | 9 | 3 | |
| ** MAII score | log2(9/385*10)=-2.09686153925259 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: PPP3CA [Title/Abstract] AND COL25A1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | PPP3CA | GO:0006470 | protein dephosphorylation | 18815128|19154138 |
| Hgene | PPP3CA | GO:0033173 | calcineurin-NFAT signaling cascade | 19154138|22688515 |
| Hgene | PPP3CA | GO:0035690 | cellular response to drug | 11005320 |
| Hgene | PPP3CA | GO:0045944 | positive regulation of transcription by RNA polymerase II | 22688515 |
| Hgene | PPP3CA | GO:0051592 | response to calcium ion | 18815128 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | BRCA | TCGA-D8-A1X5-01A | PPP3CA | chr4 | 102267896 | - | COL25A1 | chr4 | 109895715 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000512215 | ENST00000399132 | PPP3CA | chr4 | 102267896 | - | COL25A1 | chr4 | 109895715 | - |
| In-frame | ENST00000512215 | ENST00000399127 | PPP3CA | chr4 | 102267896 | - | COL25A1 | chr4 | 109895715 | - |
| In-frame | ENST00000512215 | ENST00000399126 | PPP3CA | chr4 | 102267896 | - | COL25A1 | chr4 | 109895715 | - |
| In-frame | ENST00000394854 | ENST00000399132 | PPP3CA | chr4 | 102267896 | - | COL25A1 | chr4 | 109895715 | - |
| In-frame | ENST00000394854 | ENST00000399127 | PPP3CA | chr4 | 102267896 | - | COL25A1 | chr4 | 109895715 | - |
| In-frame | ENST00000394854 | ENST00000399126 | PPP3CA | chr4 | 102267896 | - | COL25A1 | chr4 | 109895715 | - |
| In-frame | ENST00000323055 | ENST00000399132 | PPP3CA | chr4 | 102267896 | - | COL25A1 | chr4 | 109895715 | - |
| In-frame | ENST00000323055 | ENST00000399127 | PPP3CA | chr4 | 102267896 | - | COL25A1 | chr4 | 109895715 | - |
| In-frame | ENST00000323055 | ENST00000399126 | PPP3CA | chr4 | 102267896 | - | COL25A1 | chr4 | 109895715 | - |
| In-frame | ENST00000394853 | ENST00000399132 | PPP3CA | chr4 | 102267896 | - | COL25A1 | chr4 | 109895715 | - |
| In-frame | ENST00000394853 | ENST00000399127 | PPP3CA | chr4 | 102267896 | - | COL25A1 | chr4 | 109895715 | - |
| In-frame | ENST00000394853 | ENST00000399126 | PPP3CA | chr4 | 102267896 | - | COL25A1 | chr4 | 109895715 | - |
| 5UTR-3CDS | ENST00000507176 | ENST00000399132 | PPP3CA | chr4 | 102267896 | - | COL25A1 | chr4 | 109895715 | - |
| 5UTR-3CDS | ENST00000507176 | ENST00000399127 | PPP3CA | chr4 | 102267896 | - | COL25A1 | chr4 | 109895715 | - |
| 5UTR-3CDS | ENST00000507176 | ENST00000399126 | PPP3CA | chr4 | 102267896 | - | COL25A1 | chr4 | 109895715 | - |
| In-frame | ENST00000523694 | ENST00000399132 | PPP3CA | chr4 | 102267896 | - | COL25A1 | chr4 | 109895715 | - |
| In-frame | ENST00000523694 | ENST00000399127 | PPP3CA | chr4 | 102267896 | - | COL25A1 | chr4 | 109895715 | - |
| In-frame | ENST00000523694 | ENST00000399126 | PPP3CA | chr4 | 102267896 | - | COL25A1 | chr4 | 109895715 | - |
| intron-3CDS | ENST00000510292 | ENST00000399132 | PPP3CA | chr4 | 102267896 | - | COL25A1 | chr4 | 109895715 | - |
| intron-3CDS | ENST00000510292 | ENST00000399127 | PPP3CA | chr4 | 102267896 | - | COL25A1 | chr4 | 109895715 | - |
| intron-3CDS | ENST00000510292 | ENST00000399126 | PPP3CA | chr4 | 102267896 | - | COL25A1 | chr4 | 109895715 | - |
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FusionProtFeatures for PPP3CA_COL25A1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| PPP3CA | COL25A1 |
| Calcium-dependent, calmodulin-stimulated proteinphosphatase which plays an essential role in the transduction ofintracellular Ca(2+)-mediated signals (PubMed:15671020,PubMed:18838687, PubMed:19154138, PubMed:23468591). Many of thesubstrates contain a PxIxIT motif and/or a LxVP motif(PubMed:17498738, PubMed:17502104, PubMed:23468591,PubMed:27974827, PubMed:22343722). In response to increased Ca(2+)levels, dephosphorylates and activates phosphatase SSH1 whichresults in cofilin dephosphorylation (PubMed:15671020). Inresponse to increased Ca(2+) levels following mitochondrialdepolarization, dephosphorylates DNM1L inducing DNM1Ltranslocation to the mitochondrion (PubMed:18838687).Dephosphorylates heat shock protein HSPB1 (By similarity).Dephosphorylates and activates transcription factor NFATC1(PubMed:19154138). In response to increased Ca(2+) levels,regulates NFAT-mediated transcription probably bydephosphorylating NFAT and promoting its nuclear translocation(PubMed:26248042). Dephosphorylates and inactivates transcriptionfactor ELK1 (PubMed:19154138). Dephosphorylates DARPP32(PubMed:19154138). {ECO:0000250|UniProtKB:P48452,ECO:0000269|PubMed:15671020, ECO:0000269|PubMed:17498738,ECO:0000269|PubMed:17502104, ECO:0000269|PubMed:18838687,ECO:0000269|PubMed:19154138, ECO:0000269|PubMed:22343722,ECO:0000269|PubMed:23468591, ECO:0000269|PubMed:26248042,ECO:0000269|PubMed:27974827}. | Inhibits fibrillization of amyloid-beta peptide duringthe elongation phase. Has also been shown to assemble amyloidfibrils into protease-resistant aggregates. Binds heparin.{ECO:0000269|PubMed:15522881, ECO:0000269|PubMed:15615705,ECO:0000269|PubMed:15853808, ECO:0000269|PubMed:16300410}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >COL25A1 | chr4:102267896 | chr4:109895715 | ENST00000399126 | - | 5 | 35 | 192_247 | 146 | 643 | Domain | Collagen-like 2 |
| Tgene | >COL25A1 | chr4:102267896 | chr4:109895715 | ENST00000399126 | - | 5 | 35 | 249_308 | 146 | 643 | Domain | Collagen-like 3 |
| Tgene | >COL25A1 | chr4:102267896 | chr4:109895715 | ENST00000399126 | - | 5 | 35 | 311_370 | 146 | 643 | Domain | Collagen-like 4 |
| Tgene | >COL25A1 | chr4:102267896 | chr4:109895715 | ENST00000399126 | - | 5 | 35 | 372_425 | 146 | 643 | Domain | Collagen-like 5 |
| Tgene | >COL25A1 | chr4:102267896 | chr4:109895715 | ENST00000399126 | - | 5 | 35 | 447_505 | 146 | 643 | Domain | Collagen-like 6 |
| Tgene | >COL25A1 | chr4:102267896 | chr4:109895715 | ENST00000399126 | - | 5 | 35 | 571_630 | 146 | 643 | Domain | Collagen-like 7 |
| Tgene | >COL25A1 | chr4:102267896 | chr4:109895715 | ENST00000399132 | - | 5 | 38 | 192_247 | 146 | 655 | Domain | Collagen-like 2 |
| Tgene | >COL25A1 | chr4:102267896 | chr4:109895715 | ENST00000399132 | - | 5 | 38 | 249_308 | 146 | 655 | Domain | Collagen-like 3 |
| Tgene | >COL25A1 | chr4:102267896 | chr4:109895715 | ENST00000399132 | - | 5 | 38 | 311_370 | 146 | 655 | Domain | Collagen-like 4 |
| Tgene | >COL25A1 | chr4:102267896 | chr4:109895715 | ENST00000399132 | - | 5 | 38 | 372_425 | 146 | 655 | Domain | Collagen-like 5 |
| Tgene | >COL25A1 | chr4:102267896 | chr4:109895715 | ENST00000399132 | - | 5 | 38 | 447_505 | 146 | 655 | Domain | Collagen-like 6 |
| Tgene | >COL25A1 | chr4:102267896 | chr4:109895715 | ENST00000399132 | - | 5 | 38 | 571_630 | 146 | 655 | Domain | Collagen-like 7 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >PPP3CA | chr4:102267896 | chr4:109895715 | ENST00000323055 | - | 1 | 12 | 307_311 | 19 | 470 | Motif | SAPNY motif |
| Hgene | >PPP3CA | chr4:102267896 | chr4:109895715 | ENST00000394853 | - | 1 | 13 | 307_311 | 19 | 512 | Motif | SAPNY motif |
| Hgene | >PPP3CA | chr4:102267896 | chr4:109895715 | ENST00000394854 | - | 1 | 14 | 307_311 | 19 | 522 | Motif | SAPNY motif |
| Hgene | >PPP3CA | chr4:102267896 | chr4:109895715 | ENST00000512215 | - | 1 | 8 | 307_311 | 19 | 290 | Motif | SAPNY motif |
| Hgene | >PPP3CA | chr4:102267896 | chr4:109895715 | ENST00000323055 | - | 1 | 12 | 341_369 | 19 | 470 | Region | Calcineurin B binding |
| Hgene | >PPP3CA | chr4:102267896 | chr4:109895715 | ENST00000323055 | - | 1 | 12 | 392_406 | 19 | 470 | Region | Calmodulin-binding |
| Hgene | >PPP3CA | chr4:102267896 | chr4:109895715 | ENST00000323055 | - | 1 | 12 | 407_414 | 19 | 470 | Region | Autoinhibitory segment |
| Hgene | >PPP3CA | chr4:102267896 | chr4:109895715 | ENST00000323055 | - | 1 | 12 | 465_487 | 19 | 470 | Region | Autoinhibitory domain |
| Hgene | >PPP3CA | chr4:102267896 | chr4:109895715 | ENST00000323055 | - | 1 | 12 | 56_340 | 19 | 470 | Region | Catalytic |
| Hgene | >PPP3CA | chr4:102267896 | chr4:109895715 | ENST00000394853 | - | 1 | 13 | 341_369 | 19 | 512 | Region | Calcineurin B binding |
| Hgene | >PPP3CA | chr4:102267896 | chr4:109895715 | ENST00000394853 | - | 1 | 13 | 392_406 | 19 | 512 | Region | Calmodulin-binding |
| Hgene | >PPP3CA | chr4:102267896 | chr4:109895715 | ENST00000394853 | - | 1 | 13 | 407_414 | 19 | 512 | Region | Autoinhibitory segment |
| Hgene | >PPP3CA | chr4:102267896 | chr4:109895715 | ENST00000394853 | - | 1 | 13 | 465_487 | 19 | 512 | Region | Autoinhibitory domain |
| Hgene | >PPP3CA | chr4:102267896 | chr4:109895715 | ENST00000394853 | - | 1 | 13 | 56_340 | 19 | 512 | Region | Catalytic |
| Hgene | >PPP3CA | chr4:102267896 | chr4:109895715 | ENST00000394854 | - | 1 | 14 | 341_369 | 19 | 522 | Region | Calcineurin B binding |
| Hgene | >PPP3CA | chr4:102267896 | chr4:109895715 | ENST00000394854 | - | 1 | 14 | 392_406 | 19 | 522 | Region | Calmodulin-binding |
| Hgene | >PPP3CA | chr4:102267896 | chr4:109895715 | ENST00000394854 | - | 1 | 14 | 407_414 | 19 | 522 | Region | Autoinhibitory segment |
| Hgene | >PPP3CA | chr4:102267896 | chr4:109895715 | ENST00000394854 | - | 1 | 14 | 465_487 | 19 | 522 | Region | Autoinhibitory domain |
| Hgene | >PPP3CA | chr4:102267896 | chr4:109895715 | ENST00000394854 | - | 1 | 14 | 56_340 | 19 | 522 | Region | Catalytic |
| Hgene | >PPP3CA | chr4:102267896 | chr4:109895715 | ENST00000512215 | - | 1 | 8 | 341_369 | 19 | 290 | Region | Calcineurin B binding |
| Hgene | >PPP3CA | chr4:102267896 | chr4:109895715 | ENST00000512215 | - | 1 | 8 | 392_406 | 19 | 290 | Region | Calmodulin-binding |
| Hgene | >PPP3CA | chr4:102267896 | chr4:109895715 | ENST00000512215 | - | 1 | 8 | 407_414 | 19 | 290 | Region | Autoinhibitory segment |
| Hgene | >PPP3CA | chr4:102267896 | chr4:109895715 | ENST00000512215 | - | 1 | 8 | 465_487 | 19 | 290 | Region | Autoinhibitory domain |
| Hgene | >PPP3CA | chr4:102267896 | chr4:109895715 | ENST00000512215 | - | 1 | 8 | 56_340 | 19 | 290 | Region | Catalytic |
| Tgene | COL25A1 | chr4:102267896 | chr4:109895715 | ENST00000399126 | - | 5 | 35 | 121_164 | 146 | 643 | Domain | Collagen-like 1 |
| Tgene | COL25A1 | chr4:102267896 | chr4:109895715 | ENST00000399132 | - | 5 | 38 | 121_164 | 146 | 655 | Domain | Collagen-like 1 |
| Tgene | COL25A1 | chr4:102267896 | chr4:109895715 | ENST00000399126 | - | 5 | 35 | 1_33 | 146 | 643 | Topological domain | Cytoplasmic |
| Tgene | COL25A1 | chr4:102267896 | chr4:109895715 | ENST00000399126 | - | 5 | 35 | 55_654 | 146 | 643 | Topological domain | Extracellular |
| Tgene | COL25A1 | chr4:102267896 | chr4:109895715 | ENST00000399132 | - | 5 | 38 | 1_33 | 146 | 655 | Topological domain | Cytoplasmic |
| Tgene | COL25A1 | chr4:102267896 | chr4:109895715 | ENST00000399132 | - | 5 | 38 | 55_654 | 146 | 655 | Topological domain | Extracellular |
| Tgene | COL25A1 | chr4:102267896 | chr4:109895715 | ENST00000399126 | - | 5 | 35 | 34_54 | 146 | 643 | Transmembrane | Helical%3B Signal-anchor for type II membrane protein |
| Tgene | COL25A1 | chr4:102267896 | chr4:109895715 | ENST00000399132 | - | 5 | 38 | 34_54 | 146 | 655 | Transmembrane | Helical%3B Signal-anchor for type II membrane protein |
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FusionGeneSequence for PPP3CA_COL25A1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_PPP3CA_ENST00000512215_chr4_102267896_-_COL25A1_ENST00000399132_chr4_109895715_-_528aa MSEPKAIDPKLSTTDRVVKGPSWSKRRXGRTRXSGTXDGVSXNQSWVSLCXSAAHXTPPDXGXPRTGRASRTPWPSRPKRATWGHRERWP PWNARSTRXTRKARRTRLDGSSRASGTKGFYWSTWNSRDEWAKGXARVAWSSRTEWNTRTXGRTWRTRXKGRRWRERPQGXHRRKGXPWI ICCRNXGRTWGIWSSRAKGXTRASWASWTSGDKGRTRFHWSSRRTRLTRFTRNKRXTGGSRASWKRXARGTWSPRTKGETRXIRNXRPKG VKGGSWRKRGLWSSGTKGSTWSKRGSRSHXDHRLQRQPPRSLTEDYHLNCHGSPWTSWTSRTTRAKGRAGISRNPRNGWRAGTQRLKGRH GGPRYDRXKRRNWTSWITGSQWNERRKRRFWNAGSTGSFYHRPTRPTRSPWPTWPHGTSWTSWTKGYRWSYGTPWPCRSQRRKRXKRSYG >In-frame_PPP3CA_ENST00000512215_chr4_102267896_-_COL25A1_ENST00000399127_chr4_109895715_-_519aa MSEPKAIDPKLSTTDRVVKGPSWSKRRXGRTRXSGTXGPARLPHSCCPAQXSDPHRQGXPRTGRASRTPWPSRPKRATWGHRERWPPWNA RSTRXTRKARRTRLDGSSRASGTKGFYWSTWNSRDEWAKGXARVAWSSRTEWNTRTXGRTWRTRXKGRRWRERPQGXHRRKGXPWIICCR NXGRTWGIWSSRAKGXTRASWASWTSGDKGRTRFHWSSRRTRLTRFTRNKRXTGGSRASWKRXARGTWSPRTKGGSWRKRGLWSSGTKGS TWSKRGSRSHXDHRLQRQPPRSLTGSPWTSWTSRTTRAKGRAGISRNPRNGWRAGTQRLKGRHGGPRYDRXKRRNWTSWITGSQWNERRK RRFWNAGSTGSFYHRPTRPTRSPWPTWPHGTSWTSWTKGXTRVKWCXRIEGXTRSKGXQRTPWSSRSIWLRRKARIPGYRWSYGTPWPCR >In-frame_PPP3CA_ENST00000512215_chr4_102267896_-_COL25A1_ENST00000399126_chr4_109895715_-_516aa MSEPKAIDPKLSTTDRVVKGPSWSKRRXGRTRXSGTXDGVSXNQSWVSLCXSAAHXTPPDXGXPRTGRASRTPWPSRPKRATWGHRERWP PWNARSTRXTRKARRTRLDGSSRASGTKGFYWSTWNSRDEWAKGXARVAWSSRTEWNTRTXGRTWRTRXKGRRWRERPQGXHRRKGXPWI ICCRNXGRTWGIWSSRAKGXTRASWASWTSGDKGRTRFHWSSRRTRLTRFTRNKRXTGGSRASWKRXARGTWSPRTKGETRXIRNXRPKG VKGGSWRKRGLWSSGTKGSTWSKRGSRSHXDHRLQRQPPRSLTEDYHLNCHGSPWTSWTSRTTRAKGRAGISRNPRNGWRAGTQRLKGRH GGPRYDRXKRRNWTSWITGSQWNERRKRRFWNAGSTGSFYHRPTRPTRSPWPTWPHGTSWTSWTKGYRWSYGTPWPCRSQRRKRXKRSYG >In-frame_PPP3CA_ENST00000394854_chr4_102267896_-_COL25A1_ENST00000399132_chr4_109895715_-_528aa MSEPKAIDPKLSTTDRVVKGPSWSKRRXGRTRXSGTXDGVSXNQSWVSLCXSAAHXTPPDXGXPRTGRASRTPWPSRPKRATWGHRERWP PWNARSTRXTRKARRTRLDGSSRASGTKGFYWSTWNSRDEWAKGXARVAWSSRTEWNTRTXGRTWRTRXKGRRWRERPQGXHRRKGXPWI ICCRNXGRTWGIWSSRAKGXTRASWASWTSGDKGRTRFHWSSRRTRLTRFTRNKRXTGGSRASWKRXARGTWSPRTKGETRXIRNXRPKG VKGGSWRKRGLWSSGTKGSTWSKRGSRSHXDHRLQRQPPRSLTEDYHLNCHGSPWTSWTSRTTRAKGRAGISRNPRNGWRAGTQRLKGRH GGPRYDRXKRRNWTSWITGSQWNERRKRRFWNAGSTGSFYHRPTRPTRSPWPTWPHGTSWTSWTKGYRWSYGTPWPCRSQRRKRXKRSYG >In-frame_PPP3CA_ENST00000394854_chr4_102267896_-_COL25A1_ENST00000399127_chr4_109895715_-_519aa MSEPKAIDPKLSTTDRVVKGPSWSKRRXGRTRXSGTXGPARLPHSCCPAQXSDPHRQGXPRTGRASRTPWPSRPKRATWGHRERWPPWNA RSTRXTRKARRTRLDGSSRASGTKGFYWSTWNSRDEWAKGXARVAWSSRTEWNTRTXGRTWRTRXKGRRWRERPQGXHRRKGXPWIICCR NXGRTWGIWSSRAKGXTRASWASWTSGDKGRTRFHWSSRRTRLTRFTRNKRXTGGSRASWKRXARGTWSPRTKGGSWRKRGLWSSGTKGS TWSKRGSRSHXDHRLQRQPPRSLTGSPWTSWTSRTTRAKGRAGISRNPRNGWRAGTQRLKGRHGGPRYDRXKRRNWTSWITGSQWNERRK RRFWNAGSTGSFYHRPTRPTRSPWPTWPHGTSWTSWTKGXTRVKWCXRIEGXTRSKGXQRTPWSSRSIWLRRKARIPGYRWSYGTPWPCR >In-frame_PPP3CA_ENST00000394854_chr4_102267896_-_COL25A1_ENST00000399126_chr4_109895715_-_516aa MSEPKAIDPKLSTTDRVVKGPSWSKRRXGRTRXSGTXDGVSXNQSWVSLCXSAAHXTPPDXGXPRTGRASRTPWPSRPKRATWGHRERWP PWNARSTRXTRKARRTRLDGSSRASGTKGFYWSTWNSRDEWAKGXARVAWSSRTEWNTRTXGRTWRTRXKGRRWRERPQGXHRRKGXPWI ICCRNXGRTWGIWSSRAKGXTRASWASWTSGDKGRTRFHWSSRRTRLTRFTRNKRXTGGSRASWKRXARGTWSPRTKGETRXIRNXRPKG VKGGSWRKRGLWSSGTKGSTWSKRGSRSHXDHRLQRQPPRSLTEDYHLNCHGSPWTSWTSRTTRAKGRAGISRNPRNGWRAGTQRLKGRH GGPRYDRXKRRNWTSWITGSQWNERRKRRFWNAGSTGSFYHRPTRPTRSPWPTWPHGTSWTSWTKGYRWSYGTPWPCRSQRRKRXKRSYG >In-frame_PPP3CA_ENST00000323055_chr4_102267896_-_COL25A1_ENST00000399132_chr4_109895715_-_528aa MSEPKAIDPKLSTTDRVVKGPSWSKRRXGRTRXSGTXDGVSXNQSWVSLCXSAAHXTPPDXGXPRTGRASRTPWPSRPKRATWGHRERWP PWNARSTRXTRKARRTRLDGSSRASGTKGFYWSTWNSRDEWAKGXARVAWSSRTEWNTRTXGRTWRTRXKGRRWRERPQGXHRRKGXPWI ICCRNXGRTWGIWSSRAKGXTRASWASWTSGDKGRTRFHWSSRRTRLTRFTRNKRXTGGSRASWKRXARGTWSPRTKGETRXIRNXRPKG VKGGSWRKRGLWSSGTKGSTWSKRGSRSHXDHRLQRQPPRSLTEDYHLNCHGSPWTSWTSRTTRAKGRAGISRNPRNGWRAGTQRLKGRH GGPRYDRXKRRNWTSWITGSQWNERRKRRFWNAGSTGSFYHRPTRPTRSPWPTWPHGTSWTSWTKGYRWSYGTPWPCRSQRRKRXKRSYG >In-frame_PPP3CA_ENST00000323055_chr4_102267896_-_COL25A1_ENST00000399127_chr4_109895715_-_519aa MSEPKAIDPKLSTTDRVVKGPSWSKRRXGRTRXSGTXGPARLPHSCCPAQXSDPHRQGXPRTGRASRTPWPSRPKRATWGHRERWPPWNA RSTRXTRKARRTRLDGSSRASGTKGFYWSTWNSRDEWAKGXARVAWSSRTEWNTRTXGRTWRTRXKGRRWRERPQGXHRRKGXPWIICCR NXGRTWGIWSSRAKGXTRASWASWTSGDKGRTRFHWSSRRTRLTRFTRNKRXTGGSRASWKRXARGTWSPRTKGGSWRKRGLWSSGTKGS TWSKRGSRSHXDHRLQRQPPRSLTGSPWTSWTSRTTRAKGRAGISRNPRNGWRAGTQRLKGRHGGPRYDRXKRRNWTSWITGSQWNERRK RRFWNAGSTGSFYHRPTRPTRSPWPTWPHGTSWTSWTKGXTRVKWCXRIEGXTRSKGXQRTPWSSRSIWLRRKARIPGYRWSYGTPWPCR >In-frame_PPP3CA_ENST00000323055_chr4_102267896_-_COL25A1_ENST00000399126_chr4_109895715_-_516aa MSEPKAIDPKLSTTDRVVKGPSWSKRRXGRTRXSGTXDGVSXNQSWVSLCXSAAHXTPPDXGXPRTGRASRTPWPSRPKRATWGHRERWP PWNARSTRXTRKARRTRLDGSSRASGTKGFYWSTWNSRDEWAKGXARVAWSSRTEWNTRTXGRTWRTRXKGRRWRERPQGXHRRKGXPWI ICCRNXGRTWGIWSSRAKGXTRASWASWTSGDKGRTRFHWSSRRTRLTRFTRNKRXTGGSRASWKRXARGTWSPRTKGETRXIRNXRPKG VKGGSWRKRGLWSSGTKGSTWSKRGSRSHXDHRLQRQPPRSLTEDYHLNCHGSPWTSWTSRTTRAKGRAGISRNPRNGWRAGTQRLKGRH GGPRYDRXKRRNWTSWITGSQWNERRKRRFWNAGSTGSFYHRPTRPTRSPWPTWPHGTSWTSWTKGYRWSYGTPWPCRSQRRKRXKRSYG >In-frame_PPP3CA_ENST00000394853_chr4_102267896_-_COL25A1_ENST00000399132_chr4_109895715_-_528aa MSEPKAIDPKLSTTDRVVKGPSWSKRRXGRTRXSGTXDGVSXNQSWVSLCXSAAHXTPPDXGXPRTGRASRTPWPSRPKRATWGHRERWP PWNARSTRXTRKARRTRLDGSSRASGTKGFYWSTWNSRDEWAKGXARVAWSSRTEWNTRTXGRTWRTRXKGRRWRERPQGXHRRKGXPWI ICCRNXGRTWGIWSSRAKGXTRASWASWTSGDKGRTRFHWSSRRTRLTRFTRNKRXTGGSRASWKRXARGTWSPRTKGETRXIRNXRPKG VKGGSWRKRGLWSSGTKGSTWSKRGSRSHXDHRLQRQPPRSLTEDYHLNCHGSPWTSWTSRTTRAKGRAGISRNPRNGWRAGTQRLKGRH GGPRYDRXKRRNWTSWITGSQWNERRKRRFWNAGSTGSFYHRPTRPTRSPWPTWPHGTSWTSWTKGYRWSYGTPWPCRSQRRKRXKRSYG >In-frame_PPP3CA_ENST00000394853_chr4_102267896_-_COL25A1_ENST00000399127_chr4_109895715_-_519aa MSEPKAIDPKLSTTDRVVKGPSWSKRRXGRTRXSGTXGPARLPHSCCPAQXSDPHRQGXPRTGRASRTPWPSRPKRATWGHRERWPPWNA RSTRXTRKARRTRLDGSSRASGTKGFYWSTWNSRDEWAKGXARVAWSSRTEWNTRTXGRTWRTRXKGRRWRERPQGXHRRKGXPWIICCR NXGRTWGIWSSRAKGXTRASWASWTSGDKGRTRFHWSSRRTRLTRFTRNKRXTGGSRASWKRXARGTWSPRTKGGSWRKRGLWSSGTKGS TWSKRGSRSHXDHRLQRQPPRSLTGSPWTSWTSRTTRAKGRAGISRNPRNGWRAGTQRLKGRHGGPRYDRXKRRNWTSWITGSQWNERRK RRFWNAGSTGSFYHRPTRPTRSPWPTWPHGTSWTSWTKGXTRVKWCXRIEGXTRSKGXQRTPWSSRSIWLRRKARIPGYRWSYGTPWPCR >In-frame_PPP3CA_ENST00000394853_chr4_102267896_-_COL25A1_ENST00000399126_chr4_109895715_-_516aa MSEPKAIDPKLSTTDRVVKGPSWSKRRXGRTRXSGTXDGVSXNQSWVSLCXSAAHXTPPDXGXPRTGRASRTPWPSRPKRATWGHRERWP PWNARSTRXTRKARRTRLDGSSRASGTKGFYWSTWNSRDEWAKGXARVAWSSRTEWNTRTXGRTWRTRXKGRRWRERPQGXHRRKGXPWI ICCRNXGRTWGIWSSRAKGXTRASWASWTSGDKGRTRFHWSSRRTRLTRFTRNKRXTGGSRASWKRXARGTWSPRTKGETRXIRNXRPKG VKGGSWRKRGLWSSGTKGSTWSKRGSRSHXDHRLQRQPPRSLTEDYHLNCHGSPWTSWTSRTTRAKGRAGISRNPRNGWRAGTQRLKGRH GGPRYDRXKRRNWTSWITGSQWNERRKRRFWNAGSTGSFYHRPTRPTRSPWPTWPHGTSWTSWTKGYRWSYGTPWPCRSQRRKRXKRSYG >In-frame_PPP3CA_ENST00000523694_chr4_102267896_-_COL25A1_ENST00000399132_chr4_109895715_-_528aa MSEPKAIDPKLSTTDRVVKGPSWSKRRXGRTRXSGTXDGVSXNQSWVSLCXSAAHXTPPDXGXPRTGRASRTPWPSRPKRATWGHRERWP PWNARSTRXTRKARRTRLDGSSRASGTKGFYWSTWNSRDEWAKGXARVAWSSRTEWNTRTXGRTWRTRXKGRRWRERPQGXHRRKGXPWI ICCRNXGRTWGIWSSRAKGXTRASWASWTSGDKGRTRFHWSSRRTRLTRFTRNKRXTGGSRASWKRXARGTWSPRTKGETRXIRNXRPKG VKGGSWRKRGLWSSGTKGSTWSKRGSRSHXDHRLQRQPPRSLTEDYHLNCHGSPWTSWTSRTTRAKGRAGISRNPRNGWRAGTQRLKGRH GGPRYDRXKRRNWTSWITGSQWNERRKRRFWNAGSTGSFYHRPTRPTRSPWPTWPHGTSWTSWTKGYRWSYGTPWPCRSQRRKRXKRSYG >In-frame_PPP3CA_ENST00000523694_chr4_102267896_-_COL25A1_ENST00000399127_chr4_109895715_-_519aa MSEPKAIDPKLSTTDRVVKGPSWSKRRXGRTRXSGTXGPARLPHSCCPAQXSDPHRQGXPRTGRASRTPWPSRPKRATWGHRERWPPWNA RSTRXTRKARRTRLDGSSRASGTKGFYWSTWNSRDEWAKGXARVAWSSRTEWNTRTXGRTWRTRXKGRRWRERPQGXHRRKGXPWIICCR NXGRTWGIWSSRAKGXTRASWASWTSGDKGRTRFHWSSRRTRLTRFTRNKRXTGGSRASWKRXARGTWSPRTKGGSWRKRGLWSSGTKGS TWSKRGSRSHXDHRLQRQPPRSLTGSPWTSWTSRTTRAKGRAGISRNPRNGWRAGTQRLKGRHGGPRYDRXKRRNWTSWITGSQWNERRK RRFWNAGSTGSFYHRPTRPTRSPWPTWPHGTSWTSWTKGXTRVKWCXRIEGXTRSKGXQRTPWSSRSIWLRRKARIPGYRWSYGTPWPCR >In-frame_PPP3CA_ENST00000523694_chr4_102267896_-_COL25A1_ENST00000399126_chr4_109895715_-_516aa MSEPKAIDPKLSTTDRVVKGPSWSKRRXGRTRXSGTXDGVSXNQSWVSLCXSAAHXTPPDXGXPRTGRASRTPWPSRPKRATWGHRERWP PWNARSTRXTRKARRTRLDGSSRASGTKGFYWSTWNSRDEWAKGXARVAWSSRTEWNTRTXGRTWRTRXKGRRWRERPQGXHRRKGXPWI ICCRNXGRTWGIWSSRAKGXTRASWASWTSGDKGRTRFHWSSRRTRLTRFTRNKRXTGGSRASWKRXARGTWSPRTKGETRXIRNXRPKG VKGGSWRKRGLWSSGTKGSTWSKRGSRSHXDHRLQRQPPRSLTEDYHLNCHGSPWTSWTSRTTRAKGRAGISRNPRNGWRAGTQRLKGRH GGPRYDRXKRRNWTSWITGSQWNERRKRRFWNAGSTGSFYHRPTRPTRSPWPTWPHGTSWTSWTKGYRWSYGTPWPCRSQRRKRXKRSYG |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_PPP3CA_ENST00000512215_chr4_102267896_-_COL25A1_ENST00000399132_chr4_109895715_-_1585nt ATGTCCGAGCCCAAGGCAATTGATCCCAAGTTGTCGACGACCGACAGGGTGGTGAAAGGGCCCTCCTGGTCCAAAAGGCGATAAGGGAGA ACAAGGTGATCAGGGACCTAGGATGGTGTTTCCTAAAATCAATCATGGGTTTCTCTCTGCTGATCAGCAGCTCATTAAACGCCGCCTGAT TAAGGGTGACCAAGGACAGGCAGGGCCTCCAGGACCCCCTGGCCCTCCAGGCCCAAGAGGGCCACCTGGGGACACAGGGAAAGATGGCCC CCGTGGAATGCCAGGAGTACCCGGTGAACCAGGAAAGCCAGGAGAACAAGGCTTGATGGGTCCTCTAGGGCCTCCGGGACAAAAGGGTTC TATTGGAGCACCTGGAATTCCAGGGATGAATGGGCAAAAGGGTGAGCCCGGGTTGCCTGGAGCAGTAGGACAGAATGGAATACCAGGACC TAAGGGAGAACCTGGAGAACAAGGTGAAAAGGGAGACGCTGGAGAGAACGGCCCCAAGGGTGACACAGGCGAAAAGGGTGACCCTGGATC ATCTGCTGCAGGAATTAAGGGAGAACCTGGGGAATCTGGTCGTCCAGGGCAAAAGGGTGAACCAGGGCTTCCTGGGCTTCCTGGACTTCC GGGGATAAAGGGAGAACCAGGTTTCATTGGTCCTCAAGGAGAACCAGGCTTACCAGGTTTACCAGGAACAAAAGGTGAACGGGGGGAAGC AGGGCCTCCTGGAAGAGGTGAGCGAGGGGAACCTGGAGCCCCCGGACCAAAGGGGAAACAAGGTGAATCAGGAACTAGAGGCCCAAAGGG GTCAAAGGGGGATCGTGGAGAAAAAGGGGACTCTGGAGCTCAGGGACCAAGGGGTCCACCTGGTCAAAAAGGGGATCAAGGAGCCACTGA GATCATAGACTACAACGGCAACCTCCACGAAGCCTTACAGAGGATTACCACCTTAACTGTCACGGGTCCCCCTGGACCTCCTGGACCTCA AGGACTACAAGGGCCAAAGGGAGAGCAGGGATCTCCAGGAATCCCAGGAATGGATGGAGAGCAGGGACTCAAAGGCTCAAAGGGAGACAT GGGGGACCCAGGTATGACAGGTGAAAAAGGAGGAATTGGACTTCCTGGATTACCGGGAGCCAATGGAATGAAAGGAGAAAAAGGAGATTC TGGAATGCCGGGTCCACAGGGTCCTTCTATCATAGGCCCACCAGGCCCACCAGGTCCCCATGGCCCACCTGGCCCCATGGGACCTCATGG ACTTCCTGGACCAAAGGGTACAGATGGTCCTATGGGACCCCATGGCCCTGCAGGTCCCAAAGGAGAAAGAGGTGAAAAAGGAGCTATGGG AGAGCCTGGACCAAGAGGGCCCTATGGGCTGCCTGGGAAAGATGGAGAGCCTGGTCTTGATGGCTTCCCTGGTCCACGGGGTGAGAAGGG TGATCTAGGAGAAAAGGGAGAAAAGGGATTCCGTGGCGTTAAGGGGGAAAAAGGGGAGCCAGGCCAGCCTGGCCTGGATGGGCTGGATGC >In-frame_PPP3CA_ENST00000512215_chr4_102267896_-_COL25A1_ENST00000399127_chr4_109895715_-_1558nt ATGTCCGAGCCCAAGGCAATTGATCCCAAGTTGTCGACGACCGACAGGGTGGTGAAAGGGCCCTCCTGGTCCAAAAGGCGATAAGGGAGA ACAAGGTGATCAGGGACCTAGGGGCCTGCCAGGCTTCCCCACAGTTGCTGCCCTGCACAGTAATCAGATCCTCACCGTCAAGGGTGACCA AGGACAGGCAGGGCCTCCAGGACCCCCTGGCCCTCCAGGCCCAAGAGGGCCACCTGGGGACACAGGGAAAGATGGCCCCCGTGGAATGCC AGGAGTACCCGGTGAACCAGGAAAGCCAGGAGAACAAGGCTTGATGGGTCCTCTAGGGCCTCCGGGACAAAAGGGTTCTATTGGAGCACC TGGAATTCCAGGGATGAATGGGCAAAAGGGTGAGCCCGGGTTGCCTGGAGCAGTAGGACAGAATGGAATACCAGGACCTAAGGGAGAACC TGGAGAACAAGGTGAAAAGGGAGACGCTGGAGAGAACGGCCCCAAGGGTGACACAGGCGAAAAGGGTGACCCTGGATCATCTGCTGCAGG AATTAAGGGAGAACCTGGGGAATCTGGTCGTCCAGGGCAAAAGGGTGAACCAGGGCTTCCTGGGCTTCCTGGACTTCCGGGGATAAAGGG AGAACCAGGTTTCATTGGTCCTCAAGGAGAACCAGGCTTACCAGGTTTACCAGGAACAAAAGGTGAACGGGGGGAAGCAGGGCCTCCTGG AAGAGGTGAGCGAGGGGAACCTGGAGCCCCCGGACCAAAGGGGGATCGTGGAGAAAAAGGGGACTCTGGAGCTCAGGGACCAAGGGGTCC ACCTGGTCAAAAAGGGGATCAAGGAGCCACTGAGATCATAGACTACAACGGCAACCTCCACGAAGCCTTACAGGGTCCCCCTGGACCTCC TGGACCTCAAGGACTACAAGGGCCAAAGGGAGAGCAGGGATCTCCAGGAATCCCAGGAATGGATGGAGAGCAGGGACTCAAAGGCTCAAA GGGAGACATGGGGGACCCAGGTATGACAGGTGAAAAAGGAGGAATTGGACTTCCTGGATTACCGGGAGCCAATGGAATGAAAGGAGAAAA AGGAGATTCTGGAATGCCGGGTCCACAGGGTCCTTCTATCATAGGCCCACCAGGCCCACCAGGTCCCCATGGCCCACCTGGCCCCATGGG ACCTCATGGACTTCCTGGACCAAAGGGTGAACCAGGGTTAAATGGTGTTAAAGGATTGAAGGGTGAACCAGGTCAAAAGGGTGACAGAGG ACCCCTTGGTCTTCCAGGAGCATCTGGCTTAGACGGAAAGCCAGGATCCCGGGGTACAGATGGTCCTATGGGACCCCATGGCCCTGCAGG TCCCAAAGGAGAAAGAGGTGAAAAAGGAGCTATGGGAGAGCCTGGACCAAGAGGGCCCTATGGGCTGCCTGGCTTCCCTGGTCCACGGGG TGAGAAGGGTGATCTAGGAGAAAAGGGAGAAAAGGTGACCTCTCCATCCCAGCATGTACCTTGTTTGATTCTTCTCCTGCTGTCTGCTTT >In-frame_PPP3CA_ENST00000512215_chr4_102267896_-_COL25A1_ENST00000399126_chr4_109895715_-_1549nt ATGTCCGAGCCCAAGGCAATTGATCCCAAGTTGTCGACGACCGACAGGGTGGTGAAAGGGCCCTCCTGGTCCAAAAGGCGATAAGGGAGA ACAAGGTGATCAGGGACCTAGGATGGTGTTTCCTAAAATCAATCATGGGTTTCTCTCTGCTGATCAGCAGCTCATTAAACGCCGCCTGAT TAAGGGTGACCAAGGACAGGCAGGGCCTCCAGGACCCCCTGGCCCTCCAGGCCCAAGAGGGCCACCTGGGGACACAGGGAAAGATGGCCC CCGTGGAATGCCAGGAGTACCCGGTGAACCAGGAAAGCCAGGAGAACAAGGCTTGATGGGTCCTCTAGGGCCTCCGGGACAAAAGGGTTC TATTGGAGCACCTGGAATTCCAGGGATGAATGGGCAAAAGGGTGAGCCCGGGTTGCCTGGAGCAGTAGGACAGAATGGAATACCAGGACC TAAGGGAGAACCTGGAGAACAAGGTGAAAAGGGAGACGCTGGAGAGAACGGCCCCAAGGGTGACACAGGCGAAAAGGGTGACCCTGGATC ATCTGCTGCAGGAATTAAGGGAGAACCTGGGGAATCTGGTCGTCCAGGGCAAAAGGGTGAACCAGGGCTTCCTGGGCTTCCTGGACTTCC GGGGATAAAGGGAGAACCAGGTTTCATTGGTCCTCAAGGAGAACCAGGCTTACCAGGTTTACCAGGAACAAAAGGTGAACGGGGGGAAGC AGGGCCTCCTGGAAGAGGTGAGCGAGGGGAACCTGGAGCCCCCGGACCAAAGGGGAAACAAGGTGAATCAGGAACTAGAGGCCCAAAGGG GTCAAAGGGGGATCGTGGAGAAAAAGGGGACTCTGGAGCTCAGGGACCAAGGGGTCCACCTGGTCAAAAAGGGGATCAAGGAGCCACTGA GATCATAGACTACAACGGCAACCTCCACGAAGCCTTACAGAGGATTACCACCTTAACTGTCACGGGTCCCCCTGGACCTCCTGGACCTCA AGGACTACAAGGGCCAAAGGGAGAGCAGGGATCTCCAGGAATCCCAGGAATGGATGGAGAGCAGGGACTCAAAGGCTCAAAGGGAGACAT GGGGGACCCAGGTATGACAGGTGAAAAAGGAGGAATTGGACTTCCTGGATTACCGGGAGCCAATGGAATGAAAGGAGAAAAAGGAGATTC TGGAATGCCGGGTCCACAGGGTCCTTCTATCATAGGCCCACCAGGCCCACCAGGTCCCCATGGCCCACCTGGCCCCATGGGACCTCATGG ACTTCCTGGACCAAAGGGTACAGATGGTCCTATGGGACCCCATGGCCCTGCAGGTCCCAAAGGAGAAAGAGGTGAAAAAGGAGCTATGGG AGAGCCTGGACCAAGAGGGCCCTATGGGCTGCCTGGGAAAGATGGAGAGCCTGGTCTTGATGGCTTCCCTGGTCCACGGGGTGAGAAGGG TGATCTAGGAGAAAAGGGAGAAAAGGTGACCTCTCCATCCCAGCATGTACCTTGTTTGATTCTTCTCCTGCTGTCTGCTTTGCTGTTCAG >In-frame_PPP3CA_ENST00000394854_chr4_102267896_-_COL25A1_ENST00000399132_chr4_109895715_-_1585nt ATGTCCGAGCCCAAGGCAATTGATCCCAAGTTGTCGACGACCGACAGGGTGGTGAAAGGGCCCTCCTGGTCCAAAAGGCGATAAGGGAGA ACAAGGTGATCAGGGACCTAGGATGGTGTTTCCTAAAATCAATCATGGGTTTCTCTCTGCTGATCAGCAGCTCATTAAACGCCGCCTGAT TAAGGGTGACCAAGGACAGGCAGGGCCTCCAGGACCCCCTGGCCCTCCAGGCCCAAGAGGGCCACCTGGGGACACAGGGAAAGATGGCCC CCGTGGAATGCCAGGAGTACCCGGTGAACCAGGAAAGCCAGGAGAACAAGGCTTGATGGGTCCTCTAGGGCCTCCGGGACAAAAGGGTTC TATTGGAGCACCTGGAATTCCAGGGATGAATGGGCAAAAGGGTGAGCCCGGGTTGCCTGGAGCAGTAGGACAGAATGGAATACCAGGACC TAAGGGAGAACCTGGAGAACAAGGTGAAAAGGGAGACGCTGGAGAGAACGGCCCCAAGGGTGACACAGGCGAAAAGGGTGACCCTGGATC ATCTGCTGCAGGAATTAAGGGAGAACCTGGGGAATCTGGTCGTCCAGGGCAAAAGGGTGAACCAGGGCTTCCTGGGCTTCCTGGACTTCC GGGGATAAAGGGAGAACCAGGTTTCATTGGTCCTCAAGGAGAACCAGGCTTACCAGGTTTACCAGGAACAAAAGGTGAACGGGGGGAAGC AGGGCCTCCTGGAAGAGGTGAGCGAGGGGAACCTGGAGCCCCCGGACCAAAGGGGAAACAAGGTGAATCAGGAACTAGAGGCCCAAAGGG GTCAAAGGGGGATCGTGGAGAAAAAGGGGACTCTGGAGCTCAGGGACCAAGGGGTCCACCTGGTCAAAAAGGGGATCAAGGAGCCACTGA GATCATAGACTACAACGGCAACCTCCACGAAGCCTTACAGAGGATTACCACCTTAACTGTCACGGGTCCCCCTGGACCTCCTGGACCTCA AGGACTACAAGGGCCAAAGGGAGAGCAGGGATCTCCAGGAATCCCAGGAATGGATGGAGAGCAGGGACTCAAAGGCTCAAAGGGAGACAT GGGGGACCCAGGTATGACAGGTGAAAAAGGAGGAATTGGACTTCCTGGATTACCGGGAGCCAATGGAATGAAAGGAGAAAAAGGAGATTC TGGAATGCCGGGTCCACAGGGTCCTTCTATCATAGGCCCACCAGGCCCACCAGGTCCCCATGGCCCACCTGGCCCCATGGGACCTCATGG ACTTCCTGGACCAAAGGGTACAGATGGTCCTATGGGACCCCATGGCCCTGCAGGTCCCAAAGGAGAAAGAGGTGAAAAAGGAGCTATGGG AGAGCCTGGACCAAGAGGGCCCTATGGGCTGCCTGGGAAAGATGGAGAGCCTGGTCTTGATGGCTTCCCTGGTCCACGGGGTGAGAAGGG TGATCTAGGAGAAAAGGGAGAAAAGGGATTCCGTGGCGTTAAGGGGGAAAAAGGGGAGCCAGGCCAGCCTGGCCTGGATGGGCTGGATGC >In-frame_PPP3CA_ENST00000394854_chr4_102267896_-_COL25A1_ENST00000399127_chr4_109895715_-_1558nt ATGTCCGAGCCCAAGGCAATTGATCCCAAGTTGTCGACGACCGACAGGGTGGTGAAAGGGCCCTCCTGGTCCAAAAGGCGATAAGGGAGA ACAAGGTGATCAGGGACCTAGGGGCCTGCCAGGCTTCCCCACAGTTGCTGCCCTGCACAGTAATCAGATCCTCACCGTCAAGGGTGACCA AGGACAGGCAGGGCCTCCAGGACCCCCTGGCCCTCCAGGCCCAAGAGGGCCACCTGGGGACACAGGGAAAGATGGCCCCCGTGGAATGCC AGGAGTACCCGGTGAACCAGGAAAGCCAGGAGAACAAGGCTTGATGGGTCCTCTAGGGCCTCCGGGACAAAAGGGTTCTATTGGAGCACC TGGAATTCCAGGGATGAATGGGCAAAAGGGTGAGCCCGGGTTGCCTGGAGCAGTAGGACAGAATGGAATACCAGGACCTAAGGGAGAACC TGGAGAACAAGGTGAAAAGGGAGACGCTGGAGAGAACGGCCCCAAGGGTGACACAGGCGAAAAGGGTGACCCTGGATCATCTGCTGCAGG AATTAAGGGAGAACCTGGGGAATCTGGTCGTCCAGGGCAAAAGGGTGAACCAGGGCTTCCTGGGCTTCCTGGACTTCCGGGGATAAAGGG AGAACCAGGTTTCATTGGTCCTCAAGGAGAACCAGGCTTACCAGGTTTACCAGGAACAAAAGGTGAACGGGGGGAAGCAGGGCCTCCTGG AAGAGGTGAGCGAGGGGAACCTGGAGCCCCCGGACCAAAGGGGGATCGTGGAGAAAAAGGGGACTCTGGAGCTCAGGGACCAAGGGGTCC ACCTGGTCAAAAAGGGGATCAAGGAGCCACTGAGATCATAGACTACAACGGCAACCTCCACGAAGCCTTACAGGGTCCCCCTGGACCTCC TGGACCTCAAGGACTACAAGGGCCAAAGGGAGAGCAGGGATCTCCAGGAATCCCAGGAATGGATGGAGAGCAGGGACTCAAAGGCTCAAA GGGAGACATGGGGGACCCAGGTATGACAGGTGAAAAAGGAGGAATTGGACTTCCTGGATTACCGGGAGCCAATGGAATGAAAGGAGAAAA AGGAGATTCTGGAATGCCGGGTCCACAGGGTCCTTCTATCATAGGCCCACCAGGCCCACCAGGTCCCCATGGCCCACCTGGCCCCATGGG ACCTCATGGACTTCCTGGACCAAAGGGTGAACCAGGGTTAAATGGTGTTAAAGGATTGAAGGGTGAACCAGGTCAAAAGGGTGACAGAGG ACCCCTTGGTCTTCCAGGAGCATCTGGCTTAGACGGAAAGCCAGGATCCCGGGGTACAGATGGTCCTATGGGACCCCATGGCCCTGCAGG TCCCAAAGGAGAAAGAGGTGAAAAAGGAGCTATGGGAGAGCCTGGACCAAGAGGGCCCTATGGGCTGCCTGGCTTCCCTGGTCCACGGGG TGAGAAGGGTGATCTAGGAGAAAAGGGAGAAAAGGTGACCTCTCCATCCCAGCATGTACCTTGTTTGATTCTTCTCCTGCTGTCTGCTTT >In-frame_PPP3CA_ENST00000394854_chr4_102267896_-_COL25A1_ENST00000399126_chr4_109895715_-_1549nt ATGTCCGAGCCCAAGGCAATTGATCCCAAGTTGTCGACGACCGACAGGGTGGTGAAAGGGCCCTCCTGGTCCAAAAGGCGATAAGGGAGA ACAAGGTGATCAGGGACCTAGGATGGTGTTTCCTAAAATCAATCATGGGTTTCTCTCTGCTGATCAGCAGCTCATTAAACGCCGCCTGAT TAAGGGTGACCAAGGACAGGCAGGGCCTCCAGGACCCCCTGGCCCTCCAGGCCCAAGAGGGCCACCTGGGGACACAGGGAAAGATGGCCC CCGTGGAATGCCAGGAGTACCCGGTGAACCAGGAAAGCCAGGAGAACAAGGCTTGATGGGTCCTCTAGGGCCTCCGGGACAAAAGGGTTC TATTGGAGCACCTGGAATTCCAGGGATGAATGGGCAAAAGGGTGAGCCCGGGTTGCCTGGAGCAGTAGGACAGAATGGAATACCAGGACC TAAGGGAGAACCTGGAGAACAAGGTGAAAAGGGAGACGCTGGAGAGAACGGCCCCAAGGGTGACACAGGCGAAAAGGGTGACCCTGGATC ATCTGCTGCAGGAATTAAGGGAGAACCTGGGGAATCTGGTCGTCCAGGGCAAAAGGGTGAACCAGGGCTTCCTGGGCTTCCTGGACTTCC GGGGATAAAGGGAGAACCAGGTTTCATTGGTCCTCAAGGAGAACCAGGCTTACCAGGTTTACCAGGAACAAAAGGTGAACGGGGGGAAGC AGGGCCTCCTGGAAGAGGTGAGCGAGGGGAACCTGGAGCCCCCGGACCAAAGGGGAAACAAGGTGAATCAGGAACTAGAGGCCCAAAGGG GTCAAAGGGGGATCGTGGAGAAAAAGGGGACTCTGGAGCTCAGGGACCAAGGGGTCCACCTGGTCAAAAAGGGGATCAAGGAGCCACTGA GATCATAGACTACAACGGCAACCTCCACGAAGCCTTACAGAGGATTACCACCTTAACTGTCACGGGTCCCCCTGGACCTCCTGGACCTCA AGGACTACAAGGGCCAAAGGGAGAGCAGGGATCTCCAGGAATCCCAGGAATGGATGGAGAGCAGGGACTCAAAGGCTCAAAGGGAGACAT GGGGGACCCAGGTATGACAGGTGAAAAAGGAGGAATTGGACTTCCTGGATTACCGGGAGCCAATGGAATGAAAGGAGAAAAAGGAGATTC TGGAATGCCGGGTCCACAGGGTCCTTCTATCATAGGCCCACCAGGCCCACCAGGTCCCCATGGCCCACCTGGCCCCATGGGACCTCATGG ACTTCCTGGACCAAAGGGTACAGATGGTCCTATGGGACCCCATGGCCCTGCAGGTCCCAAAGGAGAAAGAGGTGAAAAAGGAGCTATGGG AGAGCCTGGACCAAGAGGGCCCTATGGGCTGCCTGGGAAAGATGGAGAGCCTGGTCTTGATGGCTTCCCTGGTCCACGGGGTGAGAAGGG TGATCTAGGAGAAAAGGGAGAAAAGGTGACCTCTCCATCCCAGCATGTACCTTGTTTGATTCTTCTCCTGCTGTCTGCTTTGCTGTTCAG >In-frame_PPP3CA_ENST00000323055_chr4_102267896_-_COL25A1_ENST00000399132_chr4_109895715_-_1585nt ATGTCCGAGCCCAAGGCAATTGATCCCAAGTTGTCGACGACCGACAGGGTGGTGAAAGGGCCCTCCTGGTCCAAAAGGCGATAAGGGAGA ACAAGGTGATCAGGGACCTAGGATGGTGTTTCCTAAAATCAATCATGGGTTTCTCTCTGCTGATCAGCAGCTCATTAAACGCCGCCTGAT TAAGGGTGACCAAGGACAGGCAGGGCCTCCAGGACCCCCTGGCCCTCCAGGCCCAAGAGGGCCACCTGGGGACACAGGGAAAGATGGCCC CCGTGGAATGCCAGGAGTACCCGGTGAACCAGGAAAGCCAGGAGAACAAGGCTTGATGGGTCCTCTAGGGCCTCCGGGACAAAAGGGTTC TATTGGAGCACCTGGAATTCCAGGGATGAATGGGCAAAAGGGTGAGCCCGGGTTGCCTGGAGCAGTAGGACAGAATGGAATACCAGGACC TAAGGGAGAACCTGGAGAACAAGGTGAAAAGGGAGACGCTGGAGAGAACGGCCCCAAGGGTGACACAGGCGAAAAGGGTGACCCTGGATC ATCTGCTGCAGGAATTAAGGGAGAACCTGGGGAATCTGGTCGTCCAGGGCAAAAGGGTGAACCAGGGCTTCCTGGGCTTCCTGGACTTCC GGGGATAAAGGGAGAACCAGGTTTCATTGGTCCTCAAGGAGAACCAGGCTTACCAGGTTTACCAGGAACAAAAGGTGAACGGGGGGAAGC AGGGCCTCCTGGAAGAGGTGAGCGAGGGGAACCTGGAGCCCCCGGACCAAAGGGGAAACAAGGTGAATCAGGAACTAGAGGCCCAAAGGG GTCAAAGGGGGATCGTGGAGAAAAAGGGGACTCTGGAGCTCAGGGACCAAGGGGTCCACCTGGTCAAAAAGGGGATCAAGGAGCCACTGA GATCATAGACTACAACGGCAACCTCCACGAAGCCTTACAGAGGATTACCACCTTAACTGTCACGGGTCCCCCTGGACCTCCTGGACCTCA AGGACTACAAGGGCCAAAGGGAGAGCAGGGATCTCCAGGAATCCCAGGAATGGATGGAGAGCAGGGACTCAAAGGCTCAAAGGGAGACAT GGGGGACCCAGGTATGACAGGTGAAAAAGGAGGAATTGGACTTCCTGGATTACCGGGAGCCAATGGAATGAAAGGAGAAAAAGGAGATTC TGGAATGCCGGGTCCACAGGGTCCTTCTATCATAGGCCCACCAGGCCCACCAGGTCCCCATGGCCCACCTGGCCCCATGGGACCTCATGG ACTTCCTGGACCAAAGGGTACAGATGGTCCTATGGGACCCCATGGCCCTGCAGGTCCCAAAGGAGAAAGAGGTGAAAAAGGAGCTATGGG AGAGCCTGGACCAAGAGGGCCCTATGGGCTGCCTGGGAAAGATGGAGAGCCTGGTCTTGATGGCTTCCCTGGTCCACGGGGTGAGAAGGG TGATCTAGGAGAAAAGGGAGAAAAGGGATTCCGTGGCGTTAAGGGGGAAAAAGGGGAGCCAGGCCAGCCTGGCCTGGATGGGCTGGATGC >In-frame_PPP3CA_ENST00000323055_chr4_102267896_-_COL25A1_ENST00000399127_chr4_109895715_-_1558nt ATGTCCGAGCCCAAGGCAATTGATCCCAAGTTGTCGACGACCGACAGGGTGGTGAAAGGGCCCTCCTGGTCCAAAAGGCGATAAGGGAGA ACAAGGTGATCAGGGACCTAGGGGCCTGCCAGGCTTCCCCACAGTTGCTGCCCTGCACAGTAATCAGATCCTCACCGTCAAGGGTGACCA AGGACAGGCAGGGCCTCCAGGACCCCCTGGCCCTCCAGGCCCAAGAGGGCCACCTGGGGACACAGGGAAAGATGGCCCCCGTGGAATGCC AGGAGTACCCGGTGAACCAGGAAAGCCAGGAGAACAAGGCTTGATGGGTCCTCTAGGGCCTCCGGGACAAAAGGGTTCTATTGGAGCACC TGGAATTCCAGGGATGAATGGGCAAAAGGGTGAGCCCGGGTTGCCTGGAGCAGTAGGACAGAATGGAATACCAGGACCTAAGGGAGAACC TGGAGAACAAGGTGAAAAGGGAGACGCTGGAGAGAACGGCCCCAAGGGTGACACAGGCGAAAAGGGTGACCCTGGATCATCTGCTGCAGG AATTAAGGGAGAACCTGGGGAATCTGGTCGTCCAGGGCAAAAGGGTGAACCAGGGCTTCCTGGGCTTCCTGGACTTCCGGGGATAAAGGG AGAACCAGGTTTCATTGGTCCTCAAGGAGAACCAGGCTTACCAGGTTTACCAGGAACAAAAGGTGAACGGGGGGAAGCAGGGCCTCCTGG AAGAGGTGAGCGAGGGGAACCTGGAGCCCCCGGACCAAAGGGGGATCGTGGAGAAAAAGGGGACTCTGGAGCTCAGGGACCAAGGGGTCC ACCTGGTCAAAAAGGGGATCAAGGAGCCACTGAGATCATAGACTACAACGGCAACCTCCACGAAGCCTTACAGGGTCCCCCTGGACCTCC TGGACCTCAAGGACTACAAGGGCCAAAGGGAGAGCAGGGATCTCCAGGAATCCCAGGAATGGATGGAGAGCAGGGACTCAAAGGCTCAAA GGGAGACATGGGGGACCCAGGTATGACAGGTGAAAAAGGAGGAATTGGACTTCCTGGATTACCGGGAGCCAATGGAATGAAAGGAGAAAA AGGAGATTCTGGAATGCCGGGTCCACAGGGTCCTTCTATCATAGGCCCACCAGGCCCACCAGGTCCCCATGGCCCACCTGGCCCCATGGG ACCTCATGGACTTCCTGGACCAAAGGGTGAACCAGGGTTAAATGGTGTTAAAGGATTGAAGGGTGAACCAGGTCAAAAGGGTGACAGAGG ACCCCTTGGTCTTCCAGGAGCATCTGGCTTAGACGGAAAGCCAGGATCCCGGGGTACAGATGGTCCTATGGGACCCCATGGCCCTGCAGG TCCCAAAGGAGAAAGAGGTGAAAAAGGAGCTATGGGAGAGCCTGGACCAAGAGGGCCCTATGGGCTGCCTGGCTTCCCTGGTCCACGGGG TGAGAAGGGTGATCTAGGAGAAAAGGGAGAAAAGGTGACCTCTCCATCCCAGCATGTACCTTGTTTGATTCTTCTCCTGCTGTCTGCTTT >In-frame_PPP3CA_ENST00000323055_chr4_102267896_-_COL25A1_ENST00000399126_chr4_109895715_-_1549nt ATGTCCGAGCCCAAGGCAATTGATCCCAAGTTGTCGACGACCGACAGGGTGGTGAAAGGGCCCTCCTGGTCCAAAAGGCGATAAGGGAGA ACAAGGTGATCAGGGACCTAGGATGGTGTTTCCTAAAATCAATCATGGGTTTCTCTCTGCTGATCAGCAGCTCATTAAACGCCGCCTGAT TAAGGGTGACCAAGGACAGGCAGGGCCTCCAGGACCCCCTGGCCCTCCAGGCCCAAGAGGGCCACCTGGGGACACAGGGAAAGATGGCCC CCGTGGAATGCCAGGAGTACCCGGTGAACCAGGAAAGCCAGGAGAACAAGGCTTGATGGGTCCTCTAGGGCCTCCGGGACAAAAGGGTTC TATTGGAGCACCTGGAATTCCAGGGATGAATGGGCAAAAGGGTGAGCCCGGGTTGCCTGGAGCAGTAGGACAGAATGGAATACCAGGACC TAAGGGAGAACCTGGAGAACAAGGTGAAAAGGGAGACGCTGGAGAGAACGGCCCCAAGGGTGACACAGGCGAAAAGGGTGACCCTGGATC ATCTGCTGCAGGAATTAAGGGAGAACCTGGGGAATCTGGTCGTCCAGGGCAAAAGGGTGAACCAGGGCTTCCTGGGCTTCCTGGACTTCC GGGGATAAAGGGAGAACCAGGTTTCATTGGTCCTCAAGGAGAACCAGGCTTACCAGGTTTACCAGGAACAAAAGGTGAACGGGGGGAAGC AGGGCCTCCTGGAAGAGGTGAGCGAGGGGAACCTGGAGCCCCCGGACCAAAGGGGAAACAAGGTGAATCAGGAACTAGAGGCCCAAAGGG GTCAAAGGGGGATCGTGGAGAAAAAGGGGACTCTGGAGCTCAGGGACCAAGGGGTCCACCTGGTCAAAAAGGGGATCAAGGAGCCACTGA GATCATAGACTACAACGGCAACCTCCACGAAGCCTTACAGAGGATTACCACCTTAACTGTCACGGGTCCCCCTGGACCTCCTGGACCTCA AGGACTACAAGGGCCAAAGGGAGAGCAGGGATCTCCAGGAATCCCAGGAATGGATGGAGAGCAGGGACTCAAAGGCTCAAAGGGAGACAT GGGGGACCCAGGTATGACAGGTGAAAAAGGAGGAATTGGACTTCCTGGATTACCGGGAGCCAATGGAATGAAAGGAGAAAAAGGAGATTC TGGAATGCCGGGTCCACAGGGTCCTTCTATCATAGGCCCACCAGGCCCACCAGGTCCCCATGGCCCACCTGGCCCCATGGGACCTCATGG ACTTCCTGGACCAAAGGGTACAGATGGTCCTATGGGACCCCATGGCCCTGCAGGTCCCAAAGGAGAAAGAGGTGAAAAAGGAGCTATGGG AGAGCCTGGACCAAGAGGGCCCTATGGGCTGCCTGGGAAAGATGGAGAGCCTGGTCTTGATGGCTTCCCTGGTCCACGGGGTGAGAAGGG TGATCTAGGAGAAAAGGGAGAAAAGGTGACCTCTCCATCCCAGCATGTACCTTGTTTGATTCTTCTCCTGCTGTCTGCTTTGCTGTTCAG >In-frame_PPP3CA_ENST00000394853_chr4_102267896_-_COL25A1_ENST00000399132_chr4_109895715_-_1585nt ATGTCCGAGCCCAAGGCAATTGATCCCAAGTTGTCGACGACCGACAGGGTGGTGAAAGGGCCCTCCTGGTCCAAAAGGCGATAAGGGAGA ACAAGGTGATCAGGGACCTAGGATGGTGTTTCCTAAAATCAATCATGGGTTTCTCTCTGCTGATCAGCAGCTCATTAAACGCCGCCTGAT TAAGGGTGACCAAGGACAGGCAGGGCCTCCAGGACCCCCTGGCCCTCCAGGCCCAAGAGGGCCACCTGGGGACACAGGGAAAGATGGCCC CCGTGGAATGCCAGGAGTACCCGGTGAACCAGGAAAGCCAGGAGAACAAGGCTTGATGGGTCCTCTAGGGCCTCCGGGACAAAAGGGTTC TATTGGAGCACCTGGAATTCCAGGGATGAATGGGCAAAAGGGTGAGCCCGGGTTGCCTGGAGCAGTAGGACAGAATGGAATACCAGGACC TAAGGGAGAACCTGGAGAACAAGGTGAAAAGGGAGACGCTGGAGAGAACGGCCCCAAGGGTGACACAGGCGAAAAGGGTGACCCTGGATC ATCTGCTGCAGGAATTAAGGGAGAACCTGGGGAATCTGGTCGTCCAGGGCAAAAGGGTGAACCAGGGCTTCCTGGGCTTCCTGGACTTCC GGGGATAAAGGGAGAACCAGGTTTCATTGGTCCTCAAGGAGAACCAGGCTTACCAGGTTTACCAGGAACAAAAGGTGAACGGGGGGAAGC AGGGCCTCCTGGAAGAGGTGAGCGAGGGGAACCTGGAGCCCCCGGACCAAAGGGGAAACAAGGTGAATCAGGAACTAGAGGCCCAAAGGG GTCAAAGGGGGATCGTGGAGAAAAAGGGGACTCTGGAGCTCAGGGACCAAGGGGTCCACCTGGTCAAAAAGGGGATCAAGGAGCCACTGA GATCATAGACTACAACGGCAACCTCCACGAAGCCTTACAGAGGATTACCACCTTAACTGTCACGGGTCCCCCTGGACCTCCTGGACCTCA AGGACTACAAGGGCCAAAGGGAGAGCAGGGATCTCCAGGAATCCCAGGAATGGATGGAGAGCAGGGACTCAAAGGCTCAAAGGGAGACAT GGGGGACCCAGGTATGACAGGTGAAAAAGGAGGAATTGGACTTCCTGGATTACCGGGAGCCAATGGAATGAAAGGAGAAAAAGGAGATTC TGGAATGCCGGGTCCACAGGGTCCTTCTATCATAGGCCCACCAGGCCCACCAGGTCCCCATGGCCCACCTGGCCCCATGGGACCTCATGG ACTTCCTGGACCAAAGGGTACAGATGGTCCTATGGGACCCCATGGCCCTGCAGGTCCCAAAGGAGAAAGAGGTGAAAAAGGAGCTATGGG AGAGCCTGGACCAAGAGGGCCCTATGGGCTGCCTGGGAAAGATGGAGAGCCTGGTCTTGATGGCTTCCCTGGTCCACGGGGTGAGAAGGG TGATCTAGGAGAAAAGGGAGAAAAGGGATTCCGTGGCGTTAAGGGGGAAAAAGGGGAGCCAGGCCAGCCTGGCCTGGATGGGCTGGATGC >In-frame_PPP3CA_ENST00000394853_chr4_102267896_-_COL25A1_ENST00000399127_chr4_109895715_-_1558nt ATGTCCGAGCCCAAGGCAATTGATCCCAAGTTGTCGACGACCGACAGGGTGGTGAAAGGGCCCTCCTGGTCCAAAAGGCGATAAGGGAGA ACAAGGTGATCAGGGACCTAGGGGCCTGCCAGGCTTCCCCACAGTTGCTGCCCTGCACAGTAATCAGATCCTCACCGTCAAGGGTGACCA AGGACAGGCAGGGCCTCCAGGACCCCCTGGCCCTCCAGGCCCAAGAGGGCCACCTGGGGACACAGGGAAAGATGGCCCCCGTGGAATGCC AGGAGTACCCGGTGAACCAGGAAAGCCAGGAGAACAAGGCTTGATGGGTCCTCTAGGGCCTCCGGGACAAAAGGGTTCTATTGGAGCACC TGGAATTCCAGGGATGAATGGGCAAAAGGGTGAGCCCGGGTTGCCTGGAGCAGTAGGACAGAATGGAATACCAGGACCTAAGGGAGAACC TGGAGAACAAGGTGAAAAGGGAGACGCTGGAGAGAACGGCCCCAAGGGTGACACAGGCGAAAAGGGTGACCCTGGATCATCTGCTGCAGG AATTAAGGGAGAACCTGGGGAATCTGGTCGTCCAGGGCAAAAGGGTGAACCAGGGCTTCCTGGGCTTCCTGGACTTCCGGGGATAAAGGG AGAACCAGGTTTCATTGGTCCTCAAGGAGAACCAGGCTTACCAGGTTTACCAGGAACAAAAGGTGAACGGGGGGAAGCAGGGCCTCCTGG AAGAGGTGAGCGAGGGGAACCTGGAGCCCCCGGACCAAAGGGGGATCGTGGAGAAAAAGGGGACTCTGGAGCTCAGGGACCAAGGGGTCC ACCTGGTCAAAAAGGGGATCAAGGAGCCACTGAGATCATAGACTACAACGGCAACCTCCACGAAGCCTTACAGGGTCCCCCTGGACCTCC TGGACCTCAAGGACTACAAGGGCCAAAGGGAGAGCAGGGATCTCCAGGAATCCCAGGAATGGATGGAGAGCAGGGACTCAAAGGCTCAAA GGGAGACATGGGGGACCCAGGTATGACAGGTGAAAAAGGAGGAATTGGACTTCCTGGATTACCGGGAGCCAATGGAATGAAAGGAGAAAA AGGAGATTCTGGAATGCCGGGTCCACAGGGTCCTTCTATCATAGGCCCACCAGGCCCACCAGGTCCCCATGGCCCACCTGGCCCCATGGG ACCTCATGGACTTCCTGGACCAAAGGGTGAACCAGGGTTAAATGGTGTTAAAGGATTGAAGGGTGAACCAGGTCAAAAGGGTGACAGAGG ACCCCTTGGTCTTCCAGGAGCATCTGGCTTAGACGGAAAGCCAGGATCCCGGGGTACAGATGGTCCTATGGGACCCCATGGCCCTGCAGG TCCCAAAGGAGAAAGAGGTGAAAAAGGAGCTATGGGAGAGCCTGGACCAAGAGGGCCCTATGGGCTGCCTGGCTTCCCTGGTCCACGGGG TGAGAAGGGTGATCTAGGAGAAAAGGGAGAAAAGGTGACCTCTCCATCCCAGCATGTACCTTGTTTGATTCTTCTCCTGCTGTCTGCTTT >In-frame_PPP3CA_ENST00000394853_chr4_102267896_-_COL25A1_ENST00000399126_chr4_109895715_-_1549nt ATGTCCGAGCCCAAGGCAATTGATCCCAAGTTGTCGACGACCGACAGGGTGGTGAAAGGGCCCTCCTGGTCCAAAAGGCGATAAGGGAGA ACAAGGTGATCAGGGACCTAGGATGGTGTTTCCTAAAATCAATCATGGGTTTCTCTCTGCTGATCAGCAGCTCATTAAACGCCGCCTGAT TAAGGGTGACCAAGGACAGGCAGGGCCTCCAGGACCCCCTGGCCCTCCAGGCCCAAGAGGGCCACCTGGGGACACAGGGAAAGATGGCCC CCGTGGAATGCCAGGAGTACCCGGTGAACCAGGAAAGCCAGGAGAACAAGGCTTGATGGGTCCTCTAGGGCCTCCGGGACAAAAGGGTTC TATTGGAGCACCTGGAATTCCAGGGATGAATGGGCAAAAGGGTGAGCCCGGGTTGCCTGGAGCAGTAGGACAGAATGGAATACCAGGACC TAAGGGAGAACCTGGAGAACAAGGTGAAAAGGGAGACGCTGGAGAGAACGGCCCCAAGGGTGACACAGGCGAAAAGGGTGACCCTGGATC ATCTGCTGCAGGAATTAAGGGAGAACCTGGGGAATCTGGTCGTCCAGGGCAAAAGGGTGAACCAGGGCTTCCTGGGCTTCCTGGACTTCC GGGGATAAAGGGAGAACCAGGTTTCATTGGTCCTCAAGGAGAACCAGGCTTACCAGGTTTACCAGGAACAAAAGGTGAACGGGGGGAAGC AGGGCCTCCTGGAAGAGGTGAGCGAGGGGAACCTGGAGCCCCCGGACCAAAGGGGAAACAAGGTGAATCAGGAACTAGAGGCCCAAAGGG GTCAAAGGGGGATCGTGGAGAAAAAGGGGACTCTGGAGCTCAGGGACCAAGGGGTCCACCTGGTCAAAAAGGGGATCAAGGAGCCACTGA GATCATAGACTACAACGGCAACCTCCACGAAGCCTTACAGAGGATTACCACCTTAACTGTCACGGGTCCCCCTGGACCTCCTGGACCTCA AGGACTACAAGGGCCAAAGGGAGAGCAGGGATCTCCAGGAATCCCAGGAATGGATGGAGAGCAGGGACTCAAAGGCTCAAAGGGAGACAT GGGGGACCCAGGTATGACAGGTGAAAAAGGAGGAATTGGACTTCCTGGATTACCGGGAGCCAATGGAATGAAAGGAGAAAAAGGAGATTC TGGAATGCCGGGTCCACAGGGTCCTTCTATCATAGGCCCACCAGGCCCACCAGGTCCCCATGGCCCACCTGGCCCCATGGGACCTCATGG ACTTCCTGGACCAAAGGGTACAGATGGTCCTATGGGACCCCATGGCCCTGCAGGTCCCAAAGGAGAAAGAGGTGAAAAAGGAGCTATGGG AGAGCCTGGACCAAGAGGGCCCTATGGGCTGCCTGGGAAAGATGGAGAGCCTGGTCTTGATGGCTTCCCTGGTCCACGGGGTGAGAAGGG TGATCTAGGAGAAAAGGGAGAAAAGGTGACCTCTCCATCCCAGCATGTACCTTGTTTGATTCTTCTCCTGCTGTCTGCTTTGCTGTTCAG >In-frame_PPP3CA_ENST00000523694_chr4_102267896_-_COL25A1_ENST00000399132_chr4_109895715_-_1585nt ATGTCCGAGCCCAAGGCAATTGATCCCAAGTTGTCGACGACCGACAGGGTGGTGAAAGGGCCCTCCTGGTCCAAAAGGCGATAAGGGAGA ACAAGGTGATCAGGGACCTAGGATGGTGTTTCCTAAAATCAATCATGGGTTTCTCTCTGCTGATCAGCAGCTCATTAAACGCCGCCTGAT TAAGGGTGACCAAGGACAGGCAGGGCCTCCAGGACCCCCTGGCCCTCCAGGCCCAAGAGGGCCACCTGGGGACACAGGGAAAGATGGCCC CCGTGGAATGCCAGGAGTACCCGGTGAACCAGGAAAGCCAGGAGAACAAGGCTTGATGGGTCCTCTAGGGCCTCCGGGACAAAAGGGTTC TATTGGAGCACCTGGAATTCCAGGGATGAATGGGCAAAAGGGTGAGCCCGGGTTGCCTGGAGCAGTAGGACAGAATGGAATACCAGGACC TAAGGGAGAACCTGGAGAACAAGGTGAAAAGGGAGACGCTGGAGAGAACGGCCCCAAGGGTGACACAGGCGAAAAGGGTGACCCTGGATC ATCTGCTGCAGGAATTAAGGGAGAACCTGGGGAATCTGGTCGTCCAGGGCAAAAGGGTGAACCAGGGCTTCCTGGGCTTCCTGGACTTCC GGGGATAAAGGGAGAACCAGGTTTCATTGGTCCTCAAGGAGAACCAGGCTTACCAGGTTTACCAGGAACAAAAGGTGAACGGGGGGAAGC AGGGCCTCCTGGAAGAGGTGAGCGAGGGGAACCTGGAGCCCCCGGACCAAAGGGGAAACAAGGTGAATCAGGAACTAGAGGCCCAAAGGG GTCAAAGGGGGATCGTGGAGAAAAAGGGGACTCTGGAGCTCAGGGACCAAGGGGTCCACCTGGTCAAAAAGGGGATCAAGGAGCCACTGA GATCATAGACTACAACGGCAACCTCCACGAAGCCTTACAGAGGATTACCACCTTAACTGTCACGGGTCCCCCTGGACCTCCTGGACCTCA AGGACTACAAGGGCCAAAGGGAGAGCAGGGATCTCCAGGAATCCCAGGAATGGATGGAGAGCAGGGACTCAAAGGCTCAAAGGGAGACAT GGGGGACCCAGGTATGACAGGTGAAAAAGGAGGAATTGGACTTCCTGGATTACCGGGAGCCAATGGAATGAAAGGAGAAAAAGGAGATTC TGGAATGCCGGGTCCACAGGGTCCTTCTATCATAGGCCCACCAGGCCCACCAGGTCCCCATGGCCCACCTGGCCCCATGGGACCTCATGG ACTTCCTGGACCAAAGGGTACAGATGGTCCTATGGGACCCCATGGCCCTGCAGGTCCCAAAGGAGAAAGAGGTGAAAAAGGAGCTATGGG AGAGCCTGGACCAAGAGGGCCCTATGGGCTGCCTGGGAAAGATGGAGAGCCTGGTCTTGATGGCTTCCCTGGTCCACGGGGTGAGAAGGG TGATCTAGGAGAAAAGGGAGAAAAGGGATTCCGTGGCGTTAAGGGGGAAAAAGGGGAGCCAGGCCAGCCTGGCCTGGATGGGCTGGATGC >In-frame_PPP3CA_ENST00000523694_chr4_102267896_-_COL25A1_ENST00000399127_chr4_109895715_-_1558nt ATGTCCGAGCCCAAGGCAATTGATCCCAAGTTGTCGACGACCGACAGGGTGGTGAAAGGGCCCTCCTGGTCCAAAAGGCGATAAGGGAGA ACAAGGTGATCAGGGACCTAGGGGCCTGCCAGGCTTCCCCACAGTTGCTGCCCTGCACAGTAATCAGATCCTCACCGTCAAGGGTGACCA AGGACAGGCAGGGCCTCCAGGACCCCCTGGCCCTCCAGGCCCAAGAGGGCCACCTGGGGACACAGGGAAAGATGGCCCCCGTGGAATGCC AGGAGTACCCGGTGAACCAGGAAAGCCAGGAGAACAAGGCTTGATGGGTCCTCTAGGGCCTCCGGGACAAAAGGGTTCTATTGGAGCACC TGGAATTCCAGGGATGAATGGGCAAAAGGGTGAGCCCGGGTTGCCTGGAGCAGTAGGACAGAATGGAATACCAGGACCTAAGGGAGAACC TGGAGAACAAGGTGAAAAGGGAGACGCTGGAGAGAACGGCCCCAAGGGTGACACAGGCGAAAAGGGTGACCCTGGATCATCTGCTGCAGG AATTAAGGGAGAACCTGGGGAATCTGGTCGTCCAGGGCAAAAGGGTGAACCAGGGCTTCCTGGGCTTCCTGGACTTCCGGGGATAAAGGG AGAACCAGGTTTCATTGGTCCTCAAGGAGAACCAGGCTTACCAGGTTTACCAGGAACAAAAGGTGAACGGGGGGAAGCAGGGCCTCCTGG AAGAGGTGAGCGAGGGGAACCTGGAGCCCCCGGACCAAAGGGGGATCGTGGAGAAAAAGGGGACTCTGGAGCTCAGGGACCAAGGGGTCC ACCTGGTCAAAAAGGGGATCAAGGAGCCACTGAGATCATAGACTACAACGGCAACCTCCACGAAGCCTTACAGGGTCCCCCTGGACCTCC TGGACCTCAAGGACTACAAGGGCCAAAGGGAGAGCAGGGATCTCCAGGAATCCCAGGAATGGATGGAGAGCAGGGACTCAAAGGCTCAAA GGGAGACATGGGGGACCCAGGTATGACAGGTGAAAAAGGAGGAATTGGACTTCCTGGATTACCGGGAGCCAATGGAATGAAAGGAGAAAA AGGAGATTCTGGAATGCCGGGTCCACAGGGTCCTTCTATCATAGGCCCACCAGGCCCACCAGGTCCCCATGGCCCACCTGGCCCCATGGG ACCTCATGGACTTCCTGGACCAAAGGGTGAACCAGGGTTAAATGGTGTTAAAGGATTGAAGGGTGAACCAGGTCAAAAGGGTGACAGAGG ACCCCTTGGTCTTCCAGGAGCATCTGGCTTAGACGGAAAGCCAGGATCCCGGGGTACAGATGGTCCTATGGGACCCCATGGCCCTGCAGG TCCCAAAGGAGAAAGAGGTGAAAAAGGAGCTATGGGAGAGCCTGGACCAAGAGGGCCCTATGGGCTGCCTGGCTTCCCTGGTCCACGGGG TGAGAAGGGTGATCTAGGAGAAAAGGGAGAAAAGGTGACCTCTCCATCCCAGCATGTACCTTGTTTGATTCTTCTCCTGCTGTCTGCTTT >In-frame_PPP3CA_ENST00000523694_chr4_102267896_-_COL25A1_ENST00000399126_chr4_109895715_-_1549nt ATGTCCGAGCCCAAGGCAATTGATCCCAAGTTGTCGACGACCGACAGGGTGGTGAAAGGGCCCTCCTGGTCCAAAAGGCGATAAGGGAGA ACAAGGTGATCAGGGACCTAGGATGGTGTTTCCTAAAATCAATCATGGGTTTCTCTCTGCTGATCAGCAGCTCATTAAACGCCGCCTGAT TAAGGGTGACCAAGGACAGGCAGGGCCTCCAGGACCCCCTGGCCCTCCAGGCCCAAGAGGGCCACCTGGGGACACAGGGAAAGATGGCCC CCGTGGAATGCCAGGAGTACCCGGTGAACCAGGAAAGCCAGGAGAACAAGGCTTGATGGGTCCTCTAGGGCCTCCGGGACAAAAGGGTTC TATTGGAGCACCTGGAATTCCAGGGATGAATGGGCAAAAGGGTGAGCCCGGGTTGCCTGGAGCAGTAGGACAGAATGGAATACCAGGACC TAAGGGAGAACCTGGAGAACAAGGTGAAAAGGGAGACGCTGGAGAGAACGGCCCCAAGGGTGACACAGGCGAAAAGGGTGACCCTGGATC ATCTGCTGCAGGAATTAAGGGAGAACCTGGGGAATCTGGTCGTCCAGGGCAAAAGGGTGAACCAGGGCTTCCTGGGCTTCCTGGACTTCC GGGGATAAAGGGAGAACCAGGTTTCATTGGTCCTCAAGGAGAACCAGGCTTACCAGGTTTACCAGGAACAAAAGGTGAACGGGGGGAAGC AGGGCCTCCTGGAAGAGGTGAGCGAGGGGAACCTGGAGCCCCCGGACCAAAGGGGAAACAAGGTGAATCAGGAACTAGAGGCCCAAAGGG GTCAAAGGGGGATCGTGGAGAAAAAGGGGACTCTGGAGCTCAGGGACCAAGGGGTCCACCTGGTCAAAAAGGGGATCAAGGAGCCACTGA GATCATAGACTACAACGGCAACCTCCACGAAGCCTTACAGAGGATTACCACCTTAACTGTCACGGGTCCCCCTGGACCTCCTGGACCTCA AGGACTACAAGGGCCAAAGGGAGAGCAGGGATCTCCAGGAATCCCAGGAATGGATGGAGAGCAGGGACTCAAAGGCTCAAAGGGAGACAT GGGGGACCCAGGTATGACAGGTGAAAAAGGAGGAATTGGACTTCCTGGATTACCGGGAGCCAATGGAATGAAAGGAGAAAAAGGAGATTC TGGAATGCCGGGTCCACAGGGTCCTTCTATCATAGGCCCACCAGGCCCACCAGGTCCCCATGGCCCACCTGGCCCCATGGGACCTCATGG ACTTCCTGGACCAAAGGGTACAGATGGTCCTATGGGACCCCATGGCCCTGCAGGTCCCAAAGGAGAAAGAGGTGAAAAAGGAGCTATGGG AGAGCCTGGACCAAGAGGGCCCTATGGGCTGCCTGGGAAAGATGGAGAGCCTGGTCTTGATGGCTTCCCTGGTCCACGGGGTGAGAAGGG TGATCTAGGAGAAAAGGGAGAAAAGGTGACCTCTCCATCCCAGCATGTACCTTGTTTGATTCTTCTCCTGCTGTCTGCTTTGCTGTTCAG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_PPP3CA_ENST00000512215_chr4_102267896_-_COL25A1_ENST00000399132_chr4_109895715_-_2494nt GAGTGGAGGAGCGGCGCGGGGAGGCAGAGGCGAGCGCGGGCGATCGCGGCGGCGGGACGTCTCCGGCGGCCGCGGCACCAGCGGCGGCGC TCTGTGTGGAGAAGCAGGGGCAGCGGCAGCAGCAACAGCGGCAGCGGCAGCAGCAGCGGCAGCAGCGGCGGCCGCCTCTCCGCCGCCGGG GACGCCAAGGTGCGGCTGGTGGCACTGACATCGGCGGCCCTGCCTCTCCTCCCTCGCCCCCGGCCTTCCCCATGTGATCGGTCTTAATCC TGGCCGTGTGTGCGCGCGTGGGGCTCCATTCCGCGGTGCTGGGTCTCCGTGCCGGGGTGGGTGCTCGTGTGTGCGCTTCTCCTCCCCATC CCCCTTCCCCCAAGAATAAAAGAAGAACCGGGAGGCGTGCTCAGAAAATAAATAAATAACCACCACACACGCGCAGCCCGGAGCGAGTCG GCGGGGCTGGCGGCAGCGGCGGAGGAGGAGTGAAGGCGGCGGCGGCGGAGGAGGGACGCGCGGAAAAGGCAGCAACTTTAAAGCCAGCTC AGAGCCTAGACCTCCAGCCGAGCGGTTTGCAGCGCGGCGGCGGCGGCGGCGGCGGCGGCGTTGAGTGTCTGGCCCGCCGGTCCGGTCGGG GTGTGCAGTCGGACGGACGAGCAGCGCGTCGCTGTCCTCCGGCAGCTGGAGATGTCCGAGCCCAAGGCAATTGATCCCAAGTTGTCGACG ACCGACAGGGTGGTGAAAGGGCCCTCCTGGTCCAAAAGGCGATAAGGGAGAACAAGGTGATCAGGGACCTAGGATGGTGTTTCCTAAAAT CAATCATGGGTTTCTCTCTGCTGATCAGCAGCTCATTAAACGCCGCCTGATTAAGGGTGACCAAGGACAGGCAGGGCCTCCAGGACCCCC TGGCCCTCCAGGCCCAAGAGGGCCACCTGGGGACACAGGGAAAGATGGCCCCCGTGGAATGCCAGGAGTACCCGGTGAACCAGGAAAGCC AGGAGAACAAGGCTTGATGGGTCCTCTAGGGCCTCCGGGACAAAAGGGTTCTATTGGAGCACCTGGAATTCCAGGGATGAATGGGCAAAA GGGTGAGCCCGGGTTGCCTGGAGCAGTAGGACAGAATGGAATACCAGGACCTAAGGGAGAACCTGGAGAACAAGGTGAAAAGGGAGACGC TGGAGAGAACGGCCCCAAGGGTGACACAGGCGAAAAGGGTGACCCTGGATCATCTGCTGCAGGAATTAAGGGAGAACCTGGGGAATCTGG TCGTCCAGGGCAAAAGGGTGAACCAGGGCTTCCTGGGCTTCCTGGACTTCCGGGGATAAAGGGAGAACCAGGTTTCATTGGTCCTCAAGG AGAACCAGGCTTACCAGGTTTACCAGGAACAAAAGGTGAACGGGGGGAAGCAGGGCCTCCTGGAAGAGGTGAGCGAGGGGAACCTGGAGC CCCCGGACCAAAGGGGAAACAAGGTGAATCAGGAACTAGAGGCCCAAAGGGGTCAAAGGGGGATCGTGGAGAAAAAGGGGACTCTGGAGC TCAGGGACCAAGGGGTCCACCTGGTCAAAAAGGGGATCAAGGAGCCACTGAGATCATAGACTACAACGGCAACCTCCACGAAGCCTTACA GAGGATTACCACCTTAACTGTCACGGGTCCCCCTGGACCTCCTGGACCTCAAGGACTACAAGGGCCAAAGGGAGAGCAGGGATCTCCAGG AATCCCAGGAATGGATGGAGAGCAGGGACTCAAAGGCTCAAAGGGAGACATGGGGGACCCAGGTATGACAGGTGAAAAAGGAGGAATTGG ACTTCCTGGATTACCGGGAGCCAATGGAATGAAAGGAGAAAAAGGAGATTCTGGAATGCCGGGTCCACAGGGTCCTTCTATCATAGGCCC ACCAGGCCCACCAGGTCCCCATGGCCCACCTGGCCCCATGGGACCTCATGGACTTCCTGGACCAAAGGGTACAGATGGTCCTATGGGACC CCATGGCCCTGCAGGTCCCAAAGGAGAAAGAGGTGAAAAAGGAGCTATGGGAGAGCCTGGACCAAGAGGGCCCTATGGGCTGCCTGGGAA AGATGGAGAGCCTGGTCTTGATGGCTTCCCTGGTCCACGGGGTGAGAAGGGTGATCTAGGAGAAAAGGGAGAAAAGGGATTCCGTGGCGT TAAGGGGGAAAAAGGGGAGCCAGGCCAGCCTGGCCTGGATGGGCTGGATGCCCCTTGCCAATTGGGGCCAGATGGCTTACCCATGCCTGG CTGTTGGCAAAAGTGATGAATCTAACCTTTCAAGCATGAAGTTGTGTATATAAGGGTCCATTTTTAATATTTATAGTTGAAAACTGAATT GCAGATTTTACAAGTCTGAGATATGTTTACATAGGGCTGCTTCTTCCTGCTGGCAGTAGTATACATGTCCATTTTTACTCCACTTACATC >In-frame_PPP3CA_ENST00000512215_chr4_102267896_-_COL25A1_ENST00000399127_chr4_109895715_-_2453nt GAGTGGAGGAGCGGCGCGGGGAGGCAGAGGCGAGCGCGGGCGATCGCGGCGGCGGGACGTCTCCGGCGGCCGCGGCACCAGCGGCGGCGC TCTGTGTGGAGAAGCAGGGGCAGCGGCAGCAGCAACAGCGGCAGCGGCAGCAGCAGCGGCAGCAGCGGCGGCCGCCTCTCCGCCGCCGGG GACGCCAAGGTGCGGCTGGTGGCACTGACATCGGCGGCCCTGCCTCTCCTCCCTCGCCCCCGGCCTTCCCCATGTGATCGGTCTTAATCC TGGCCGTGTGTGCGCGCGTGGGGCTCCATTCCGCGGTGCTGGGTCTCCGTGCCGGGGTGGGTGCTCGTGTGTGCGCTTCTCCTCCCCATC CCCCTTCCCCCAAGAATAAAAGAAGAACCGGGAGGCGTGCTCAGAAAATAAATAAATAACCACCACACACGCGCAGCCCGGAGCGAGTCG GCGGGGCTGGCGGCAGCGGCGGAGGAGGAGTGAAGGCGGCGGCGGCGGAGGAGGGACGCGCGGAAAAGGCAGCAACTTTAAAGCCAGCTC AGAGCCTAGACCTCCAGCCGAGCGGTTTGCAGCGCGGCGGCGGCGGCGGCGGCGGCGGCGTTGAGTGTCTGGCCCGCCGGTCCGGTCGGG GTGTGCAGTCGGACGGACGAGCAGCGCGTCGCTGTCCTCCGGCAGCTGGAGATGTCCGAGCCCAAGGCAATTGATCCCAAGTTGTCGACG ACCGACAGGGTGGTGAAAGGGCCCTCCTGGTCCAAAAGGCGATAAGGGAGAACAAGGTGATCAGGGACCTAGGGGCCTGCCAGGCTTCCC CACAGTTGCTGCCCTGCACAGTAATCAGATCCTCACCGTCAAGGGTGACCAAGGACAGGCAGGGCCTCCAGGACCCCCTGGCCCTCCAGG CCCAAGAGGGCCACCTGGGGACACAGGGAAAGATGGCCCCCGTGGAATGCCAGGAGTACCCGGTGAACCAGGAAAGCCAGGAGAACAAGG CTTGATGGGTCCTCTAGGGCCTCCGGGACAAAAGGGTTCTATTGGAGCACCTGGAATTCCAGGGATGAATGGGCAAAAGGGTGAGCCCGG GTTGCCTGGAGCAGTAGGACAGAATGGAATACCAGGACCTAAGGGAGAACCTGGAGAACAAGGTGAAAAGGGAGACGCTGGAGAGAACGG CCCCAAGGGTGACACAGGCGAAAAGGGTGACCCTGGATCATCTGCTGCAGGAATTAAGGGAGAACCTGGGGAATCTGGTCGTCCAGGGCA AAAGGGTGAACCAGGGCTTCCTGGGCTTCCTGGACTTCCGGGGATAAAGGGAGAACCAGGTTTCATTGGTCCTCAAGGAGAACCAGGCTT ACCAGGTTTACCAGGAACAAAAGGTGAACGGGGGGAAGCAGGGCCTCCTGGAAGAGGTGAGCGAGGGGAACCTGGAGCCCCCGGACCAAA GGGGGATCGTGGAGAAAAAGGGGACTCTGGAGCTCAGGGACCAAGGGGTCCACCTGGTCAAAAAGGGGATCAAGGAGCCACTGAGATCAT AGACTACAACGGCAACCTCCACGAAGCCTTACAGGGTCCCCCTGGACCTCCTGGACCTCAAGGACTACAAGGGCCAAAGGGAGAGCAGGG ATCTCCAGGAATCCCAGGAATGGATGGAGAGCAGGGACTCAAAGGCTCAAAGGGAGACATGGGGGACCCAGGTATGACAGGTGAAAAAGG AGGAATTGGACTTCCTGGATTACCGGGAGCCAATGGAATGAAAGGAGAAAAAGGAGATTCTGGAATGCCGGGTCCACAGGGTCCTTCTAT CATAGGCCCACCAGGCCCACCAGGTCCCCATGGCCCACCTGGCCCCATGGGACCTCATGGACTTCCTGGACCAAAGGGTGAACCAGGGTT AAATGGTGTTAAAGGATTGAAGGGTGAACCAGGTCAAAAGGGTGACAGAGGACCCCTTGGTCTTCCAGGAGCATCTGGCTTAGACGGAAA GCCAGGATCCCGGGGTACAGATGGTCCTATGGGACCCCATGGCCCTGCAGGTCCCAAAGGAGAAAGAGGTGAAAAAGGAGCTATGGGAGA GCCTGGACCAAGAGGGCCCTATGGGCTGCCTGGCTTCCCTGGTCCACGGGGTGAGAAGGGTGATCTAGGAGAAAAGGGAGAAAAGGTGAC CTCTCCATCCCAGCATGTACCTTGTTTGATTCTTCTCCTGCTGTCTGCTTTGCTGTTCAGCTTGTGTGATTCCATTTGACACTTAATCTT TCTCCATCCTGTGCTCCAAAAACATACTGATGCCTGATTTAAGGAATCAGGTCTTCAGAGAGGAATGAAGAAGGCTGTACTGCCAGATAT AAGGGCACTGCCTGGCATAGAAGAAAAAATTATTATCACCAGATATTCTAGCTACAGTTTTTCAACCACCTGACACCAATTTATGGAAAA >In-frame_PPP3CA_ENST00000512215_chr4_102267896_-_COL25A1_ENST00000399126_chr4_109895715_-_2444nt GAGTGGAGGAGCGGCGCGGGGAGGCAGAGGCGAGCGCGGGCGATCGCGGCGGCGGGACGTCTCCGGCGGCCGCGGCACCAGCGGCGGCGC TCTGTGTGGAGAAGCAGGGGCAGCGGCAGCAGCAACAGCGGCAGCGGCAGCAGCAGCGGCAGCAGCGGCGGCCGCCTCTCCGCCGCCGGG GACGCCAAGGTGCGGCTGGTGGCACTGACATCGGCGGCCCTGCCTCTCCTCCCTCGCCCCCGGCCTTCCCCATGTGATCGGTCTTAATCC TGGCCGTGTGTGCGCGCGTGGGGCTCCATTCCGCGGTGCTGGGTCTCCGTGCCGGGGTGGGTGCTCGTGTGTGCGCTTCTCCTCCCCATC CCCCTTCCCCCAAGAATAAAAGAAGAACCGGGAGGCGTGCTCAGAAAATAAATAAATAACCACCACACACGCGCAGCCCGGAGCGAGTCG GCGGGGCTGGCGGCAGCGGCGGAGGAGGAGTGAAGGCGGCGGCGGCGGAGGAGGGACGCGCGGAAAAGGCAGCAACTTTAAAGCCAGCTC AGAGCCTAGACCTCCAGCCGAGCGGTTTGCAGCGCGGCGGCGGCGGCGGCGGCGGCGGCGTTGAGTGTCTGGCCCGCCGGTCCGGTCGGG GTGTGCAGTCGGACGGACGAGCAGCGCGTCGCTGTCCTCCGGCAGCTGGAGATGTCCGAGCCCAAGGCAATTGATCCCAAGTTGTCGACG ACCGACAGGGTGGTGAAAGGGCCCTCCTGGTCCAAAAGGCGATAAGGGAGAACAAGGTGATCAGGGACCTAGGATGGTGTTTCCTAAAAT CAATCATGGGTTTCTCTCTGCTGATCAGCAGCTCATTAAACGCCGCCTGATTAAGGGTGACCAAGGACAGGCAGGGCCTCCAGGACCCCC TGGCCCTCCAGGCCCAAGAGGGCCACCTGGGGACACAGGGAAAGATGGCCCCCGTGGAATGCCAGGAGTACCCGGTGAACCAGGAAAGCC AGGAGAACAAGGCTTGATGGGTCCTCTAGGGCCTCCGGGACAAAAGGGTTCTATTGGAGCACCTGGAATTCCAGGGATGAATGGGCAAAA GGGTGAGCCCGGGTTGCCTGGAGCAGTAGGACAGAATGGAATACCAGGACCTAAGGGAGAACCTGGAGAACAAGGTGAAAAGGGAGACGC TGGAGAGAACGGCCCCAAGGGTGACACAGGCGAAAAGGGTGACCCTGGATCATCTGCTGCAGGAATTAAGGGAGAACCTGGGGAATCTGG TCGTCCAGGGCAAAAGGGTGAACCAGGGCTTCCTGGGCTTCCTGGACTTCCGGGGATAAAGGGAGAACCAGGTTTCATTGGTCCTCAAGG AGAACCAGGCTTACCAGGTTTACCAGGAACAAAAGGTGAACGGGGGGAAGCAGGGCCTCCTGGAAGAGGTGAGCGAGGGGAACCTGGAGC CCCCGGACCAAAGGGGAAACAAGGTGAATCAGGAACTAGAGGCCCAAAGGGGTCAAAGGGGGATCGTGGAGAAAAAGGGGACTCTGGAGC TCAGGGACCAAGGGGTCCACCTGGTCAAAAAGGGGATCAAGGAGCCACTGAGATCATAGACTACAACGGCAACCTCCACGAAGCCTTACA GAGGATTACCACCTTAACTGTCACGGGTCCCCCTGGACCTCCTGGACCTCAAGGACTACAAGGGCCAAAGGGAGAGCAGGGATCTCCAGG AATCCCAGGAATGGATGGAGAGCAGGGACTCAAAGGCTCAAAGGGAGACATGGGGGACCCAGGTATGACAGGTGAAAAAGGAGGAATTGG ACTTCCTGGATTACCGGGAGCCAATGGAATGAAAGGAGAAAAAGGAGATTCTGGAATGCCGGGTCCACAGGGTCCTTCTATCATAGGCCC ACCAGGCCCACCAGGTCCCCATGGCCCACCTGGCCCCATGGGACCTCATGGACTTCCTGGACCAAAGGGTACAGATGGTCCTATGGGACC CCATGGCCCTGCAGGTCCCAAAGGAGAAAGAGGTGAAAAAGGAGCTATGGGAGAGCCTGGACCAAGAGGGCCCTATGGGCTGCCTGGGAA AGATGGAGAGCCTGGTCTTGATGGCTTCCCTGGTCCACGGGGTGAGAAGGGTGATCTAGGAGAAAAGGGAGAAAAGGTGACCTCTCCATC CCAGCATGTACCTTGTTTGATTCTTCTCCTGCTGTCTGCTTTGCTGTTCAGCTTGTGTGATTCCATTTGACACTTAATCTTTCTCCATCC TGTGCTCCAAAAACATACTGATGCCTGATTTAAGGAATCAGGTCTTCAGAGAGGAATGAAGAAGGCTGTACTGCCAGATATAAGGGCACT GCCTGGCATAGAAGAAAAAATTATTATCACCAGATATTCTAGCTACAGTTTTTCAACCACCTGACACCAATTTATGGAAAAATAAAGGAT >In-frame_PPP3CA_ENST00000394854_chr4_102267896_-_COL25A1_ENST00000399132_chr4_109895715_-_2497nt GGTGAGTGGAGGAGCGGCGCGGGGAGGCAGAGGCGAGCGCGGGCGATCGCGGCGGCGGGACGTCTCCGGCGGCCGCGGCACCAGCGGCGG CGCTCTGTGTGGAGAAGCAGGGGCAGCGGCAGCAGCAACAGCGGCAGCGGCAGCAGCAGCGGCAGCAGCGGCGGCCGCCTCTCCGCCGCC GGGGACGCCAAGGTGCGGCTGGTGGCACTGACATCGGCGGCCCTGCCTCTCCTCCCTCGCCCCCGGCCTTCCCCATGTGATCGGTCTTAA TCCTGGCCGTGTGTGCGCGCGTGGGGCTCCATTCCGCGGTGCTGGGTCTCCGTGCCGGGGTGGGTGCTCGTGTGTGCGCTTCTCCTCCCC ATCCCCCTTCCCCCAAGAATAAAAGAAGAACCGGGAGGCGTGCTCAGAAAATAAATAAATAACCACCACACACGCGCAGCCCGGAGCGAG TCGGCGGGGCTGGCGGCAGCGGCGGAGGAGGAGTGAAGGCGGCGGCGGCGGAGGAGGGACGCGCGGAAAAGGCAGCAACTTTAAAGCCAG CTCAGAGCCTAGACCTCCAGCCGAGCGGTTTGCAGCGCGGCGGCGGCGGCGGCGGCGGCGGCGTTGAGTGTCTGGCCCGCCGGTCCGGTC GGGGTGTGCAGTCGGACGGACGAGCAGCGCGTCGCTGTCCTCCGGCAGCTGGAGATGTCCGAGCCCAAGGCAATTGATCCCAAGTTGTCG ACGACCGACAGGGTGGTGAAAGGGCCCTCCTGGTCCAAAAGGCGATAAGGGAGAACAAGGTGATCAGGGACCTAGGATGGTGTTTCCTAA AATCAATCATGGGTTTCTCTCTGCTGATCAGCAGCTCATTAAACGCCGCCTGATTAAGGGTGACCAAGGACAGGCAGGGCCTCCAGGACC CCCTGGCCCTCCAGGCCCAAGAGGGCCACCTGGGGACACAGGGAAAGATGGCCCCCGTGGAATGCCAGGAGTACCCGGTGAACCAGGAAA GCCAGGAGAACAAGGCTTGATGGGTCCTCTAGGGCCTCCGGGACAAAAGGGTTCTATTGGAGCACCTGGAATTCCAGGGATGAATGGGCA AAAGGGTGAGCCCGGGTTGCCTGGAGCAGTAGGACAGAATGGAATACCAGGACCTAAGGGAGAACCTGGAGAACAAGGTGAAAAGGGAGA CGCTGGAGAGAACGGCCCCAAGGGTGACACAGGCGAAAAGGGTGACCCTGGATCATCTGCTGCAGGAATTAAGGGAGAACCTGGGGAATC TGGTCGTCCAGGGCAAAAGGGTGAACCAGGGCTTCCTGGGCTTCCTGGACTTCCGGGGATAAAGGGAGAACCAGGTTTCATTGGTCCTCA AGGAGAACCAGGCTTACCAGGTTTACCAGGAACAAAAGGTGAACGGGGGGAAGCAGGGCCTCCTGGAAGAGGTGAGCGAGGGGAACCTGG AGCCCCCGGACCAAAGGGGAAACAAGGTGAATCAGGAACTAGAGGCCCAAAGGGGTCAAAGGGGGATCGTGGAGAAAAAGGGGACTCTGG AGCTCAGGGACCAAGGGGTCCACCTGGTCAAAAAGGGGATCAAGGAGCCACTGAGATCATAGACTACAACGGCAACCTCCACGAAGCCTT ACAGAGGATTACCACCTTAACTGTCACGGGTCCCCCTGGACCTCCTGGACCTCAAGGACTACAAGGGCCAAAGGGAGAGCAGGGATCTCC AGGAATCCCAGGAATGGATGGAGAGCAGGGACTCAAAGGCTCAAAGGGAGACATGGGGGACCCAGGTATGACAGGTGAAAAAGGAGGAAT TGGACTTCCTGGATTACCGGGAGCCAATGGAATGAAAGGAGAAAAAGGAGATTCTGGAATGCCGGGTCCACAGGGTCCTTCTATCATAGG CCCACCAGGCCCACCAGGTCCCCATGGCCCACCTGGCCCCATGGGACCTCATGGACTTCCTGGACCAAAGGGTACAGATGGTCCTATGGG ACCCCATGGCCCTGCAGGTCCCAAAGGAGAAAGAGGTGAAAAAGGAGCTATGGGAGAGCCTGGACCAAGAGGGCCCTATGGGCTGCCTGG GAAAGATGGAGAGCCTGGTCTTGATGGCTTCCCTGGTCCACGGGGTGAGAAGGGTGATCTAGGAGAAAAGGGAGAAAAGGGATTCCGTGG CGTTAAGGGGGAAAAAGGGGAGCCAGGCCAGCCTGGCCTGGATGGGCTGGATGCCCCTTGCCAATTGGGGCCAGATGGCTTACCCATGCC TGGCTGTTGGCAAAAGTGATGAATCTAACCTTTCAAGCATGAAGTTGTGTATATAAGGGTCCATTTTTAATATTTATAGTTGAAAACTGA ATTGCAGATTTTACAAGTCTGAGATATGTTTACATAGGGCTGCTTCTTCCTGCTGGCAGTAGTATACATGTCCATTTTTACTCCACTTAC >In-frame_PPP3CA_ENST00000394854_chr4_102267896_-_COL25A1_ENST00000399127_chr4_109895715_-_2456nt GGTGAGTGGAGGAGCGGCGCGGGGAGGCAGAGGCGAGCGCGGGCGATCGCGGCGGCGGGACGTCTCCGGCGGCCGCGGCACCAGCGGCGG CGCTCTGTGTGGAGAAGCAGGGGCAGCGGCAGCAGCAACAGCGGCAGCGGCAGCAGCAGCGGCAGCAGCGGCGGCCGCCTCTCCGCCGCC GGGGACGCCAAGGTGCGGCTGGTGGCACTGACATCGGCGGCCCTGCCTCTCCTCCCTCGCCCCCGGCCTTCCCCATGTGATCGGTCTTAA TCCTGGCCGTGTGTGCGCGCGTGGGGCTCCATTCCGCGGTGCTGGGTCTCCGTGCCGGGGTGGGTGCTCGTGTGTGCGCTTCTCCTCCCC ATCCCCCTTCCCCCAAGAATAAAAGAAGAACCGGGAGGCGTGCTCAGAAAATAAATAAATAACCACCACACACGCGCAGCCCGGAGCGAG TCGGCGGGGCTGGCGGCAGCGGCGGAGGAGGAGTGAAGGCGGCGGCGGCGGAGGAGGGACGCGCGGAAAAGGCAGCAACTTTAAAGCCAG CTCAGAGCCTAGACCTCCAGCCGAGCGGTTTGCAGCGCGGCGGCGGCGGCGGCGGCGGCGGCGTTGAGTGTCTGGCCCGCCGGTCCGGTC GGGGTGTGCAGTCGGACGGACGAGCAGCGCGTCGCTGTCCTCCGGCAGCTGGAGATGTCCGAGCCCAAGGCAATTGATCCCAAGTTGTCG ACGACCGACAGGGTGGTGAAAGGGCCCTCCTGGTCCAAAAGGCGATAAGGGAGAACAAGGTGATCAGGGACCTAGGGGCCTGCCAGGCTT CCCCACAGTTGCTGCCCTGCACAGTAATCAGATCCTCACCGTCAAGGGTGACCAAGGACAGGCAGGGCCTCCAGGACCCCCTGGCCCTCC AGGCCCAAGAGGGCCACCTGGGGACACAGGGAAAGATGGCCCCCGTGGAATGCCAGGAGTACCCGGTGAACCAGGAAAGCCAGGAGAACA AGGCTTGATGGGTCCTCTAGGGCCTCCGGGACAAAAGGGTTCTATTGGAGCACCTGGAATTCCAGGGATGAATGGGCAAAAGGGTGAGCC CGGGTTGCCTGGAGCAGTAGGACAGAATGGAATACCAGGACCTAAGGGAGAACCTGGAGAACAAGGTGAAAAGGGAGACGCTGGAGAGAA CGGCCCCAAGGGTGACACAGGCGAAAAGGGTGACCCTGGATCATCTGCTGCAGGAATTAAGGGAGAACCTGGGGAATCTGGTCGTCCAGG GCAAAAGGGTGAACCAGGGCTTCCTGGGCTTCCTGGACTTCCGGGGATAAAGGGAGAACCAGGTTTCATTGGTCCTCAAGGAGAACCAGG CTTACCAGGTTTACCAGGAACAAAAGGTGAACGGGGGGAAGCAGGGCCTCCTGGAAGAGGTGAGCGAGGGGAACCTGGAGCCCCCGGACC AAAGGGGGATCGTGGAGAAAAAGGGGACTCTGGAGCTCAGGGACCAAGGGGTCCACCTGGTCAAAAAGGGGATCAAGGAGCCACTGAGAT CATAGACTACAACGGCAACCTCCACGAAGCCTTACAGGGTCCCCCTGGACCTCCTGGACCTCAAGGACTACAAGGGCCAAAGGGAGAGCA GGGATCTCCAGGAATCCCAGGAATGGATGGAGAGCAGGGACTCAAAGGCTCAAAGGGAGACATGGGGGACCCAGGTATGACAGGTGAAAA AGGAGGAATTGGACTTCCTGGATTACCGGGAGCCAATGGAATGAAAGGAGAAAAAGGAGATTCTGGAATGCCGGGTCCACAGGGTCCTTC TATCATAGGCCCACCAGGCCCACCAGGTCCCCATGGCCCACCTGGCCCCATGGGACCTCATGGACTTCCTGGACCAAAGGGTGAACCAGG GTTAAATGGTGTTAAAGGATTGAAGGGTGAACCAGGTCAAAAGGGTGACAGAGGACCCCTTGGTCTTCCAGGAGCATCTGGCTTAGACGG AAAGCCAGGATCCCGGGGTACAGATGGTCCTATGGGACCCCATGGCCCTGCAGGTCCCAAAGGAGAAAGAGGTGAAAAAGGAGCTATGGG AGAGCCTGGACCAAGAGGGCCCTATGGGCTGCCTGGCTTCCCTGGTCCACGGGGTGAGAAGGGTGATCTAGGAGAAAAGGGAGAAAAGGT GACCTCTCCATCCCAGCATGTACCTTGTTTGATTCTTCTCCTGCTGTCTGCTTTGCTGTTCAGCTTGTGTGATTCCATTTGACACTTAAT CTTTCTCCATCCTGTGCTCCAAAAACATACTGATGCCTGATTTAAGGAATCAGGTCTTCAGAGAGGAATGAAGAAGGCTGTACTGCCAGA TATAAGGGCACTGCCTGGCATAGAAGAAAAAATTATTATCACCAGATATTCTAGCTACAGTTTTTCAACCACCTGACACCAATTTATGGA >In-frame_PPP3CA_ENST00000394854_chr4_102267896_-_COL25A1_ENST00000399126_chr4_109895715_-_2447nt GGTGAGTGGAGGAGCGGCGCGGGGAGGCAGAGGCGAGCGCGGGCGATCGCGGCGGCGGGACGTCTCCGGCGGCCGCGGCACCAGCGGCGG CGCTCTGTGTGGAGAAGCAGGGGCAGCGGCAGCAGCAACAGCGGCAGCGGCAGCAGCAGCGGCAGCAGCGGCGGCCGCCTCTCCGCCGCC GGGGACGCCAAGGTGCGGCTGGTGGCACTGACATCGGCGGCCCTGCCTCTCCTCCCTCGCCCCCGGCCTTCCCCATGTGATCGGTCTTAA TCCTGGCCGTGTGTGCGCGCGTGGGGCTCCATTCCGCGGTGCTGGGTCTCCGTGCCGGGGTGGGTGCTCGTGTGTGCGCTTCTCCTCCCC ATCCCCCTTCCCCCAAGAATAAAAGAAGAACCGGGAGGCGTGCTCAGAAAATAAATAAATAACCACCACACACGCGCAGCCCGGAGCGAG TCGGCGGGGCTGGCGGCAGCGGCGGAGGAGGAGTGAAGGCGGCGGCGGCGGAGGAGGGACGCGCGGAAAAGGCAGCAACTTTAAAGCCAG CTCAGAGCCTAGACCTCCAGCCGAGCGGTTTGCAGCGCGGCGGCGGCGGCGGCGGCGGCGGCGTTGAGTGTCTGGCCCGCCGGTCCGGTC GGGGTGTGCAGTCGGACGGACGAGCAGCGCGTCGCTGTCCTCCGGCAGCTGGAGATGTCCGAGCCCAAGGCAATTGATCCCAAGTTGTCG ACGACCGACAGGGTGGTGAAAGGGCCCTCCTGGTCCAAAAGGCGATAAGGGAGAACAAGGTGATCAGGGACCTAGGATGGTGTTTCCTAA AATCAATCATGGGTTTCTCTCTGCTGATCAGCAGCTCATTAAACGCCGCCTGATTAAGGGTGACCAAGGACAGGCAGGGCCTCCAGGACC CCCTGGCCCTCCAGGCCCAAGAGGGCCACCTGGGGACACAGGGAAAGATGGCCCCCGTGGAATGCCAGGAGTACCCGGTGAACCAGGAAA GCCAGGAGAACAAGGCTTGATGGGTCCTCTAGGGCCTCCGGGACAAAAGGGTTCTATTGGAGCACCTGGAATTCCAGGGATGAATGGGCA AAAGGGTGAGCCCGGGTTGCCTGGAGCAGTAGGACAGAATGGAATACCAGGACCTAAGGGAGAACCTGGAGAACAAGGTGAAAAGGGAGA CGCTGGAGAGAACGGCCCCAAGGGTGACACAGGCGAAAAGGGTGACCCTGGATCATCTGCTGCAGGAATTAAGGGAGAACCTGGGGAATC TGGTCGTCCAGGGCAAAAGGGTGAACCAGGGCTTCCTGGGCTTCCTGGACTTCCGGGGATAAAGGGAGAACCAGGTTTCATTGGTCCTCA AGGAGAACCAGGCTTACCAGGTTTACCAGGAACAAAAGGTGAACGGGGGGAAGCAGGGCCTCCTGGAAGAGGTGAGCGAGGGGAACCTGG AGCCCCCGGACCAAAGGGGAAACAAGGTGAATCAGGAACTAGAGGCCCAAAGGGGTCAAAGGGGGATCGTGGAGAAAAAGGGGACTCTGG AGCTCAGGGACCAAGGGGTCCACCTGGTCAAAAAGGGGATCAAGGAGCCACTGAGATCATAGACTACAACGGCAACCTCCACGAAGCCTT ACAGAGGATTACCACCTTAACTGTCACGGGTCCCCCTGGACCTCCTGGACCTCAAGGACTACAAGGGCCAAAGGGAGAGCAGGGATCTCC AGGAATCCCAGGAATGGATGGAGAGCAGGGACTCAAAGGCTCAAAGGGAGACATGGGGGACCCAGGTATGACAGGTGAAAAAGGAGGAAT TGGACTTCCTGGATTACCGGGAGCCAATGGAATGAAAGGAGAAAAAGGAGATTCTGGAATGCCGGGTCCACAGGGTCCTTCTATCATAGG CCCACCAGGCCCACCAGGTCCCCATGGCCCACCTGGCCCCATGGGACCTCATGGACTTCCTGGACCAAAGGGTACAGATGGTCCTATGGG ACCCCATGGCCCTGCAGGTCCCAAAGGAGAAAGAGGTGAAAAAGGAGCTATGGGAGAGCCTGGACCAAGAGGGCCCTATGGGCTGCCTGG GAAAGATGGAGAGCCTGGTCTTGATGGCTTCCCTGGTCCACGGGGTGAGAAGGGTGATCTAGGAGAAAAGGGAGAAAAGGTGACCTCTCC ATCCCAGCATGTACCTTGTTTGATTCTTCTCCTGCTGTCTGCTTTGCTGTTCAGCTTGTGTGATTCCATTTGACACTTAATCTTTCTCCA TCCTGTGCTCCAAAAACATACTGATGCCTGATTTAAGGAATCAGGTCTTCAGAGAGGAATGAAGAAGGCTGTACTGCCAGATATAAGGGC ACTGCCTGGCATAGAAGAAAAAATTATTATCACCAGATATTCTAGCTACAGTTTTTCAACCACCTGACACCAATTTATGGAAAAATAAAG >In-frame_PPP3CA_ENST00000323055_chr4_102267896_-_COL25A1_ENST00000399132_chr4_109895715_-_2488nt AGGAGCGGCGCGGGGAGGCAGAGGCGAGCGCGGGCGATCGCGGCGGCGGGACGTCTCCGGCGGCCGCGGCACCAGCGGCGGCGCTCTGTG TGGAGAAGCAGGGGCAGCGGCAGCAGCAACAGCGGCAGCGGCAGCAGCAGCGGCAGCAGCGGCGGCCGCCTCTCCGCCGCCGGGGACGCC AAGGTGCGGCTGGTGGCACTGACATCGGCGGCCCTGCCTCTCCTCCCTCGCCCCCGGCCTTCCCCATGTGATCGGTCTTAATCCTGGCCG TGTGTGCGCGCGTGGGGCTCCATTCCGCGGTGCTGGGTCTCCGTGCCGGGGTGGGTGCTCGTGTGTGCGCTTCTCCTCCCCATCCCCCTT CCCCCAAGAATAAAAGAAGAACCGGGAGGCGTGCTCAGAAAATAAATAAATAACCACCACACACGCGCAGCCCGGAGCGAGTCGGCGGGG CTGGCGGCAGCGGCGGAGGAGGAGTGAAGGCGGCGGCGGCGGAGGAGGGACGCGCGGAAAAGGCAGCAACTTTAAAGCCAGCTCAGAGCC TAGACCTCCAGCCGAGCGGTTTGCAGCGCGGCGGCGGCGGCGGCGGCGGCGGCGTTGAGTGTCTGGCCCGCCGGTCCGGTCGGGGTGTGC AGTCGGACGGACGAGCAGCGCGTCGCTGTCCTCCGGCAGCTGGAGATGTCCGAGCCCAAGGCAATTGATCCCAAGTTGTCGACGACCGAC AGGGTGGTGAAAGGGCCCTCCTGGTCCAAAAGGCGATAAGGGAGAACAAGGTGATCAGGGACCTAGGATGGTGTTTCCTAAAATCAATCA TGGGTTTCTCTCTGCTGATCAGCAGCTCATTAAACGCCGCCTGATTAAGGGTGACCAAGGACAGGCAGGGCCTCCAGGACCCCCTGGCCC TCCAGGCCCAAGAGGGCCACCTGGGGACACAGGGAAAGATGGCCCCCGTGGAATGCCAGGAGTACCCGGTGAACCAGGAAAGCCAGGAGA ACAAGGCTTGATGGGTCCTCTAGGGCCTCCGGGACAAAAGGGTTCTATTGGAGCACCTGGAATTCCAGGGATGAATGGGCAAAAGGGTGA GCCCGGGTTGCCTGGAGCAGTAGGACAGAATGGAATACCAGGACCTAAGGGAGAACCTGGAGAACAAGGTGAAAAGGGAGACGCTGGAGA GAACGGCCCCAAGGGTGACACAGGCGAAAAGGGTGACCCTGGATCATCTGCTGCAGGAATTAAGGGAGAACCTGGGGAATCTGGTCGTCC AGGGCAAAAGGGTGAACCAGGGCTTCCTGGGCTTCCTGGACTTCCGGGGATAAAGGGAGAACCAGGTTTCATTGGTCCTCAAGGAGAACC AGGCTTACCAGGTTTACCAGGAACAAAAGGTGAACGGGGGGAAGCAGGGCCTCCTGGAAGAGGTGAGCGAGGGGAACCTGGAGCCCCCGG ACCAAAGGGGAAACAAGGTGAATCAGGAACTAGAGGCCCAAAGGGGTCAAAGGGGGATCGTGGAGAAAAAGGGGACTCTGGAGCTCAGGG ACCAAGGGGTCCACCTGGTCAAAAAGGGGATCAAGGAGCCACTGAGATCATAGACTACAACGGCAACCTCCACGAAGCCTTACAGAGGAT TACCACCTTAACTGTCACGGGTCCCCCTGGACCTCCTGGACCTCAAGGACTACAAGGGCCAAAGGGAGAGCAGGGATCTCCAGGAATCCC AGGAATGGATGGAGAGCAGGGACTCAAAGGCTCAAAGGGAGACATGGGGGACCCAGGTATGACAGGTGAAAAAGGAGGAATTGGACTTCC TGGATTACCGGGAGCCAATGGAATGAAAGGAGAAAAAGGAGATTCTGGAATGCCGGGTCCACAGGGTCCTTCTATCATAGGCCCACCAGG CCCACCAGGTCCCCATGGCCCACCTGGCCCCATGGGACCTCATGGACTTCCTGGACCAAAGGGTACAGATGGTCCTATGGGACCCCATGG CCCTGCAGGTCCCAAAGGAGAAAGAGGTGAAAAAGGAGCTATGGGAGAGCCTGGACCAAGAGGGCCCTATGGGCTGCCTGGGAAAGATGG AGAGCCTGGTCTTGATGGCTTCCCTGGTCCACGGGGTGAGAAGGGTGATCTAGGAGAAAAGGGAGAAAAGGGATTCCGTGGCGTTAAGGG GGAAAAAGGGGAGCCAGGCCAGCCTGGCCTGGATGGGCTGGATGCCCCTTGCCAATTGGGGCCAGATGGCTTACCCATGCCTGGCTGTTG GCAAAAGTGATGAATCTAACCTTTCAAGCATGAAGTTGTGTATATAAGGGTCCATTTTTAATATTTATAGTTGAAAACTGAATTGCAGAT TTTACAAGTCTGAGATATGTTTACATAGGGCTGCTTCTTCCTGCTGGCAGTAGTATACATGTCCATTTTTACTCCACTTACATCTGAAAT >In-frame_PPP3CA_ENST00000323055_chr4_102267896_-_COL25A1_ENST00000399127_chr4_109895715_-_2447nt AGGAGCGGCGCGGGGAGGCAGAGGCGAGCGCGGGCGATCGCGGCGGCGGGACGTCTCCGGCGGCCGCGGCACCAGCGGCGGCGCTCTGTG TGGAGAAGCAGGGGCAGCGGCAGCAGCAACAGCGGCAGCGGCAGCAGCAGCGGCAGCAGCGGCGGCCGCCTCTCCGCCGCCGGGGACGCC AAGGTGCGGCTGGTGGCACTGACATCGGCGGCCCTGCCTCTCCTCCCTCGCCCCCGGCCTTCCCCATGTGATCGGTCTTAATCCTGGCCG TGTGTGCGCGCGTGGGGCTCCATTCCGCGGTGCTGGGTCTCCGTGCCGGGGTGGGTGCTCGTGTGTGCGCTTCTCCTCCCCATCCCCCTT CCCCCAAGAATAAAAGAAGAACCGGGAGGCGTGCTCAGAAAATAAATAAATAACCACCACACACGCGCAGCCCGGAGCGAGTCGGCGGGG CTGGCGGCAGCGGCGGAGGAGGAGTGAAGGCGGCGGCGGCGGAGGAGGGACGCGCGGAAAAGGCAGCAACTTTAAAGCCAGCTCAGAGCC TAGACCTCCAGCCGAGCGGTTTGCAGCGCGGCGGCGGCGGCGGCGGCGGCGGCGTTGAGTGTCTGGCCCGCCGGTCCGGTCGGGGTGTGC AGTCGGACGGACGAGCAGCGCGTCGCTGTCCTCCGGCAGCTGGAGATGTCCGAGCCCAAGGCAATTGATCCCAAGTTGTCGACGACCGAC AGGGTGGTGAAAGGGCCCTCCTGGTCCAAAAGGCGATAAGGGAGAACAAGGTGATCAGGGACCTAGGGGCCTGCCAGGCTTCCCCACAGT TGCTGCCCTGCACAGTAATCAGATCCTCACCGTCAAGGGTGACCAAGGACAGGCAGGGCCTCCAGGACCCCCTGGCCCTCCAGGCCCAAG AGGGCCACCTGGGGACACAGGGAAAGATGGCCCCCGTGGAATGCCAGGAGTACCCGGTGAACCAGGAAAGCCAGGAGAACAAGGCTTGAT GGGTCCTCTAGGGCCTCCGGGACAAAAGGGTTCTATTGGAGCACCTGGAATTCCAGGGATGAATGGGCAAAAGGGTGAGCCCGGGTTGCC TGGAGCAGTAGGACAGAATGGAATACCAGGACCTAAGGGAGAACCTGGAGAACAAGGTGAAAAGGGAGACGCTGGAGAGAACGGCCCCAA GGGTGACACAGGCGAAAAGGGTGACCCTGGATCATCTGCTGCAGGAATTAAGGGAGAACCTGGGGAATCTGGTCGTCCAGGGCAAAAGGG TGAACCAGGGCTTCCTGGGCTTCCTGGACTTCCGGGGATAAAGGGAGAACCAGGTTTCATTGGTCCTCAAGGAGAACCAGGCTTACCAGG TTTACCAGGAACAAAAGGTGAACGGGGGGAAGCAGGGCCTCCTGGAAGAGGTGAGCGAGGGGAACCTGGAGCCCCCGGACCAAAGGGGGA TCGTGGAGAAAAAGGGGACTCTGGAGCTCAGGGACCAAGGGGTCCACCTGGTCAAAAAGGGGATCAAGGAGCCACTGAGATCATAGACTA CAACGGCAACCTCCACGAAGCCTTACAGGGTCCCCCTGGACCTCCTGGACCTCAAGGACTACAAGGGCCAAAGGGAGAGCAGGGATCTCC AGGAATCCCAGGAATGGATGGAGAGCAGGGACTCAAAGGCTCAAAGGGAGACATGGGGGACCCAGGTATGACAGGTGAAAAAGGAGGAAT TGGACTTCCTGGATTACCGGGAGCCAATGGAATGAAAGGAGAAAAAGGAGATTCTGGAATGCCGGGTCCACAGGGTCCTTCTATCATAGG CCCACCAGGCCCACCAGGTCCCCATGGCCCACCTGGCCCCATGGGACCTCATGGACTTCCTGGACCAAAGGGTGAACCAGGGTTAAATGG TGTTAAAGGATTGAAGGGTGAACCAGGTCAAAAGGGTGACAGAGGACCCCTTGGTCTTCCAGGAGCATCTGGCTTAGACGGAAAGCCAGG ATCCCGGGGTACAGATGGTCCTATGGGACCCCATGGCCCTGCAGGTCCCAAAGGAGAAAGAGGTGAAAAAGGAGCTATGGGAGAGCCTGG ACCAAGAGGGCCCTATGGGCTGCCTGGCTTCCCTGGTCCACGGGGTGAGAAGGGTGATCTAGGAGAAAAGGGAGAAAAGGTGACCTCTCC ATCCCAGCATGTACCTTGTTTGATTCTTCTCCTGCTGTCTGCTTTGCTGTTCAGCTTGTGTGATTCCATTTGACACTTAATCTTTCTCCA TCCTGTGCTCCAAAAACATACTGATGCCTGATTTAAGGAATCAGGTCTTCAGAGAGGAATGAAGAAGGCTGTACTGCCAGATATAAGGGC ACTGCCTGGCATAGAAGAAAAAATTATTATCACCAGATATTCTAGCTACAGTTTTTCAACCACCTGACACCAATTTATGGAAAAATAAAG >In-frame_PPP3CA_ENST00000323055_chr4_102267896_-_COL25A1_ENST00000399126_chr4_109895715_-_2438nt AGGAGCGGCGCGGGGAGGCAGAGGCGAGCGCGGGCGATCGCGGCGGCGGGACGTCTCCGGCGGCCGCGGCACCAGCGGCGGCGCTCTGTG TGGAGAAGCAGGGGCAGCGGCAGCAGCAACAGCGGCAGCGGCAGCAGCAGCGGCAGCAGCGGCGGCCGCCTCTCCGCCGCCGGGGACGCC AAGGTGCGGCTGGTGGCACTGACATCGGCGGCCCTGCCTCTCCTCCCTCGCCCCCGGCCTTCCCCATGTGATCGGTCTTAATCCTGGCCG TGTGTGCGCGCGTGGGGCTCCATTCCGCGGTGCTGGGTCTCCGTGCCGGGGTGGGTGCTCGTGTGTGCGCTTCTCCTCCCCATCCCCCTT CCCCCAAGAATAAAAGAAGAACCGGGAGGCGTGCTCAGAAAATAAATAAATAACCACCACACACGCGCAGCCCGGAGCGAGTCGGCGGGG CTGGCGGCAGCGGCGGAGGAGGAGTGAAGGCGGCGGCGGCGGAGGAGGGACGCGCGGAAAAGGCAGCAACTTTAAAGCCAGCTCAGAGCC TAGACCTCCAGCCGAGCGGTTTGCAGCGCGGCGGCGGCGGCGGCGGCGGCGGCGTTGAGTGTCTGGCCCGCCGGTCCGGTCGGGGTGTGC AGTCGGACGGACGAGCAGCGCGTCGCTGTCCTCCGGCAGCTGGAGATGTCCGAGCCCAAGGCAATTGATCCCAAGTTGTCGACGACCGAC AGGGTGGTGAAAGGGCCCTCCTGGTCCAAAAGGCGATAAGGGAGAACAAGGTGATCAGGGACCTAGGATGGTGTTTCCTAAAATCAATCA TGGGTTTCTCTCTGCTGATCAGCAGCTCATTAAACGCCGCCTGATTAAGGGTGACCAAGGACAGGCAGGGCCTCCAGGACCCCCTGGCCC TCCAGGCCCAAGAGGGCCACCTGGGGACACAGGGAAAGATGGCCCCCGTGGAATGCCAGGAGTACCCGGTGAACCAGGAAAGCCAGGAGA ACAAGGCTTGATGGGTCCTCTAGGGCCTCCGGGACAAAAGGGTTCTATTGGAGCACCTGGAATTCCAGGGATGAATGGGCAAAAGGGTGA GCCCGGGTTGCCTGGAGCAGTAGGACAGAATGGAATACCAGGACCTAAGGGAGAACCTGGAGAACAAGGTGAAAAGGGAGACGCTGGAGA GAACGGCCCCAAGGGTGACACAGGCGAAAAGGGTGACCCTGGATCATCTGCTGCAGGAATTAAGGGAGAACCTGGGGAATCTGGTCGTCC AGGGCAAAAGGGTGAACCAGGGCTTCCTGGGCTTCCTGGACTTCCGGGGATAAAGGGAGAACCAGGTTTCATTGGTCCTCAAGGAGAACC AGGCTTACCAGGTTTACCAGGAACAAAAGGTGAACGGGGGGAAGCAGGGCCTCCTGGAAGAGGTGAGCGAGGGGAACCTGGAGCCCCCGG ACCAAAGGGGAAACAAGGTGAATCAGGAACTAGAGGCCCAAAGGGGTCAAAGGGGGATCGTGGAGAAAAAGGGGACTCTGGAGCTCAGGG ACCAAGGGGTCCACCTGGTCAAAAAGGGGATCAAGGAGCCACTGAGATCATAGACTACAACGGCAACCTCCACGAAGCCTTACAGAGGAT TACCACCTTAACTGTCACGGGTCCCCCTGGACCTCCTGGACCTCAAGGACTACAAGGGCCAAAGGGAGAGCAGGGATCTCCAGGAATCCC AGGAATGGATGGAGAGCAGGGACTCAAAGGCTCAAAGGGAGACATGGGGGACCCAGGTATGACAGGTGAAAAAGGAGGAATTGGACTTCC TGGATTACCGGGAGCCAATGGAATGAAAGGAGAAAAAGGAGATTCTGGAATGCCGGGTCCACAGGGTCCTTCTATCATAGGCCCACCAGG CCCACCAGGTCCCCATGGCCCACCTGGCCCCATGGGACCTCATGGACTTCCTGGACCAAAGGGTACAGATGGTCCTATGGGACCCCATGG CCCTGCAGGTCCCAAAGGAGAAAGAGGTGAAAAAGGAGCTATGGGAGAGCCTGGACCAAGAGGGCCCTATGGGCTGCCTGGGAAAGATGG AGAGCCTGGTCTTGATGGCTTCCCTGGTCCACGGGGTGAGAAGGGTGATCTAGGAGAAAAGGGAGAAAAGGTGACCTCTCCATCCCAGCA TGTACCTTGTTTGATTCTTCTCCTGCTGTCTGCTTTGCTGTTCAGCTTGTGTGATTCCATTTGACACTTAATCTTTCTCCATCCTGTGCT CCAAAAACATACTGATGCCTGATTTAAGGAATCAGGTCTTCAGAGAGGAATGAAGAAGGCTGTACTGCCAGATATAAGGGCACTGCCTGG CATAGAAGAAAAAATTATTATCACCAGATATTCTAGCTACAGTTTTTCAACCACCTGACACCAATTTATGGAAAAATAAAGGATTTTTGA >In-frame_PPP3CA_ENST00000394853_chr4_102267896_-_COL25A1_ENST00000399132_chr4_109895715_-_2344nt AGCAGCGGCGGCCGCCTCTCCGCCGCCGGGGACGCCAAGGTGCGGCTGGTGGCACTGACATCGGCGGCCCTGCCTCTCCTCCCTCGCCCC CGGCCTTCCCCATGTGATCGGTCTTAATCCTGGCCGTGTGTGCGCGCGTGGGGCTCCATTCCGCGGTGCTGGGTCTCCGTGCCGGGGTGG GTGCTCGTGTGTGCGCTTCTCCTCCCCATCCCCCTTCCCCCAAGAATAAAAGAAGAACCGGGAGGCGTGCTCAGAAAATAAATAAATAAC CACCACACACGCGCAGCCCGGAGCGAGTCGGCGGGGCTGGCGGCAGCGGCGGAGGAGGAGTGAAGGCGGCGGCGGCGGAGGAGGGACGCG CGGAAAAGGCAGCAACTTTAAAGCCAGCTCAGAGCCTAGACCTCCAGCCGAGCGGTTTGCAGCGCGGCGGCGGCGGCGGCGGCGGCGGCG TTGAGTGTCTGGCCCGCCGGTCCGGTCGGGGTGTGCAGTCGGACGGACGAGCAGCGCGTCGCTGTCCTCCGGCAGCTGGAGATGTCCGAG CCCAAGGCAATTGATCCCAAGTTGTCGACGACCGACAGGGTGGTGAAAGGGCCCTCCTGGTCCAAAAGGCGATAAGGGAGAACAAGGTGA TCAGGGACCTAGGATGGTGTTTCCTAAAATCAATCATGGGTTTCTCTCTGCTGATCAGCAGCTCATTAAACGCCGCCTGATTAAGGGTGA CCAAGGACAGGCAGGGCCTCCAGGACCCCCTGGCCCTCCAGGCCCAAGAGGGCCACCTGGGGACACAGGGAAAGATGGCCCCCGTGGAAT GCCAGGAGTACCCGGTGAACCAGGAAAGCCAGGAGAACAAGGCTTGATGGGTCCTCTAGGGCCTCCGGGACAAAAGGGTTCTATTGGAGC ACCTGGAATTCCAGGGATGAATGGGCAAAAGGGTGAGCCCGGGTTGCCTGGAGCAGTAGGACAGAATGGAATACCAGGACCTAAGGGAGA ACCTGGAGAACAAGGTGAAAAGGGAGACGCTGGAGAGAACGGCCCCAAGGGTGACACAGGCGAAAAGGGTGACCCTGGATCATCTGCTGC AGGAATTAAGGGAGAACCTGGGGAATCTGGTCGTCCAGGGCAAAAGGGTGAACCAGGGCTTCCTGGGCTTCCTGGACTTCCGGGGATAAA GGGAGAACCAGGTTTCATTGGTCCTCAAGGAGAACCAGGCTTACCAGGTTTACCAGGAACAAAAGGTGAACGGGGGGAAGCAGGGCCTCC TGGAAGAGGTGAGCGAGGGGAACCTGGAGCCCCCGGACCAAAGGGGAAACAAGGTGAATCAGGAACTAGAGGCCCAAAGGGGTCAAAGGG GGATCGTGGAGAAAAAGGGGACTCTGGAGCTCAGGGACCAAGGGGTCCACCTGGTCAAAAAGGGGATCAAGGAGCCACTGAGATCATAGA CTACAACGGCAACCTCCACGAAGCCTTACAGAGGATTACCACCTTAACTGTCACGGGTCCCCCTGGACCTCCTGGACCTCAAGGACTACA AGGGCCAAAGGGAGAGCAGGGATCTCCAGGAATCCCAGGAATGGATGGAGAGCAGGGACTCAAAGGCTCAAAGGGAGACATGGGGGACCC AGGTATGACAGGTGAAAAAGGAGGAATTGGACTTCCTGGATTACCGGGAGCCAATGGAATGAAAGGAGAAAAAGGAGATTCTGGAATGCC GGGTCCACAGGGTCCTTCTATCATAGGCCCACCAGGCCCACCAGGTCCCCATGGCCCACCTGGCCCCATGGGACCTCATGGACTTCCTGG ACCAAAGGGTACAGATGGTCCTATGGGACCCCATGGCCCTGCAGGTCCCAAAGGAGAAAGAGGTGAAAAAGGAGCTATGGGAGAGCCTGG ACCAAGAGGGCCCTATGGGCTGCCTGGGAAAGATGGAGAGCCTGGTCTTGATGGCTTCCCTGGTCCACGGGGTGAGAAGGGTGATCTAGG AGAAAAGGGAGAAAAGGGATTCCGTGGCGTTAAGGGGGAAAAAGGGGAGCCAGGCCAGCCTGGCCTGGATGGGCTGGATGCCCCTTGCCA ATTGGGGCCAGATGGCTTACCCATGCCTGGCTGTTGGCAAAAGTGATGAATCTAACCTTTCAAGCATGAAGTTGTGTATATAAGGGTCCA TTTTTAATATTTATAGTTGAAAACTGAATTGCAGATTTTACAAGTCTGAGATATGTTTACATAGGGCTGCTTCTTCCTGCTGGCAGTAGT ATACATGTCCATTTTTACTCCACTTACATCTGAAATTGGGCAATTTGTGAAACCAGTGAGAATCCTGCAAAAAATATAGATCAGTATCTC >In-frame_PPP3CA_ENST00000394853_chr4_102267896_-_COL25A1_ENST00000399127_chr4_109895715_-_2303nt AGCAGCGGCGGCCGCCTCTCCGCCGCCGGGGACGCCAAGGTGCGGCTGGTGGCACTGACATCGGCGGCCCTGCCTCTCCTCCCTCGCCCC CGGCCTTCCCCATGTGATCGGTCTTAATCCTGGCCGTGTGTGCGCGCGTGGGGCTCCATTCCGCGGTGCTGGGTCTCCGTGCCGGGGTGG GTGCTCGTGTGTGCGCTTCTCCTCCCCATCCCCCTTCCCCCAAGAATAAAAGAAGAACCGGGAGGCGTGCTCAGAAAATAAATAAATAAC CACCACACACGCGCAGCCCGGAGCGAGTCGGCGGGGCTGGCGGCAGCGGCGGAGGAGGAGTGAAGGCGGCGGCGGCGGAGGAGGGACGCG CGGAAAAGGCAGCAACTTTAAAGCCAGCTCAGAGCCTAGACCTCCAGCCGAGCGGTTTGCAGCGCGGCGGCGGCGGCGGCGGCGGCGGCG TTGAGTGTCTGGCCCGCCGGTCCGGTCGGGGTGTGCAGTCGGACGGACGAGCAGCGCGTCGCTGTCCTCCGGCAGCTGGAGATGTCCGAG CCCAAGGCAATTGATCCCAAGTTGTCGACGACCGACAGGGTGGTGAAAGGGCCCTCCTGGTCCAAAAGGCGATAAGGGAGAACAAGGTGA TCAGGGACCTAGGGGCCTGCCAGGCTTCCCCACAGTTGCTGCCCTGCACAGTAATCAGATCCTCACCGTCAAGGGTGACCAAGGACAGGC AGGGCCTCCAGGACCCCCTGGCCCTCCAGGCCCAAGAGGGCCACCTGGGGACACAGGGAAAGATGGCCCCCGTGGAATGCCAGGAGTACC CGGTGAACCAGGAAAGCCAGGAGAACAAGGCTTGATGGGTCCTCTAGGGCCTCCGGGACAAAAGGGTTCTATTGGAGCACCTGGAATTCC AGGGATGAATGGGCAAAAGGGTGAGCCCGGGTTGCCTGGAGCAGTAGGACAGAATGGAATACCAGGACCTAAGGGAGAACCTGGAGAACA AGGTGAAAAGGGAGACGCTGGAGAGAACGGCCCCAAGGGTGACACAGGCGAAAAGGGTGACCCTGGATCATCTGCTGCAGGAATTAAGGG AGAACCTGGGGAATCTGGTCGTCCAGGGCAAAAGGGTGAACCAGGGCTTCCTGGGCTTCCTGGACTTCCGGGGATAAAGGGAGAACCAGG TTTCATTGGTCCTCAAGGAGAACCAGGCTTACCAGGTTTACCAGGAACAAAAGGTGAACGGGGGGAAGCAGGGCCTCCTGGAAGAGGTGA GCGAGGGGAACCTGGAGCCCCCGGACCAAAGGGGGATCGTGGAGAAAAAGGGGACTCTGGAGCTCAGGGACCAAGGGGTCCACCTGGTCA AAAAGGGGATCAAGGAGCCACTGAGATCATAGACTACAACGGCAACCTCCACGAAGCCTTACAGGGTCCCCCTGGACCTCCTGGACCTCA AGGACTACAAGGGCCAAAGGGAGAGCAGGGATCTCCAGGAATCCCAGGAATGGATGGAGAGCAGGGACTCAAAGGCTCAAAGGGAGACAT GGGGGACCCAGGTATGACAGGTGAAAAAGGAGGAATTGGACTTCCTGGATTACCGGGAGCCAATGGAATGAAAGGAGAAAAAGGAGATTC TGGAATGCCGGGTCCACAGGGTCCTTCTATCATAGGCCCACCAGGCCCACCAGGTCCCCATGGCCCACCTGGCCCCATGGGACCTCATGG ACTTCCTGGACCAAAGGGTGAACCAGGGTTAAATGGTGTTAAAGGATTGAAGGGTGAACCAGGTCAAAAGGGTGACAGAGGACCCCTTGG TCTTCCAGGAGCATCTGGCTTAGACGGAAAGCCAGGATCCCGGGGTACAGATGGTCCTATGGGACCCCATGGCCCTGCAGGTCCCAAAGG AGAAAGAGGTGAAAAAGGAGCTATGGGAGAGCCTGGACCAAGAGGGCCCTATGGGCTGCCTGGCTTCCCTGGTCCACGGGGTGAGAAGGG TGATCTAGGAGAAAAGGGAGAAAAGGTGACCTCTCCATCCCAGCATGTACCTTGTTTGATTCTTCTCCTGCTGTCTGCTTTGCTGTTCAG CTTGTGTGATTCCATTTGACACTTAATCTTTCTCCATCCTGTGCTCCAAAAACATACTGATGCCTGATTTAAGGAATCAGGTCTTCAGAG AGGAATGAAGAAGGCTGTACTGCCAGATATAAGGGCACTGCCTGGCATAGAAGAAAAAATTATTATCACCAGATATTCTAGCTACAGTTT >In-frame_PPP3CA_ENST00000394853_chr4_102267896_-_COL25A1_ENST00000399126_chr4_109895715_-_2294nt AGCAGCGGCGGCCGCCTCTCCGCCGCCGGGGACGCCAAGGTGCGGCTGGTGGCACTGACATCGGCGGCCCTGCCTCTCCTCCCTCGCCCC CGGCCTTCCCCATGTGATCGGTCTTAATCCTGGCCGTGTGTGCGCGCGTGGGGCTCCATTCCGCGGTGCTGGGTCTCCGTGCCGGGGTGG GTGCTCGTGTGTGCGCTTCTCCTCCCCATCCCCCTTCCCCCAAGAATAAAAGAAGAACCGGGAGGCGTGCTCAGAAAATAAATAAATAAC CACCACACACGCGCAGCCCGGAGCGAGTCGGCGGGGCTGGCGGCAGCGGCGGAGGAGGAGTGAAGGCGGCGGCGGCGGAGGAGGGACGCG CGGAAAAGGCAGCAACTTTAAAGCCAGCTCAGAGCCTAGACCTCCAGCCGAGCGGTTTGCAGCGCGGCGGCGGCGGCGGCGGCGGCGGCG TTGAGTGTCTGGCCCGCCGGTCCGGTCGGGGTGTGCAGTCGGACGGACGAGCAGCGCGTCGCTGTCCTCCGGCAGCTGGAGATGTCCGAG CCCAAGGCAATTGATCCCAAGTTGTCGACGACCGACAGGGTGGTGAAAGGGCCCTCCTGGTCCAAAAGGCGATAAGGGAGAACAAGGTGA TCAGGGACCTAGGATGGTGTTTCCTAAAATCAATCATGGGTTTCTCTCTGCTGATCAGCAGCTCATTAAACGCCGCCTGATTAAGGGTGA CCAAGGACAGGCAGGGCCTCCAGGACCCCCTGGCCCTCCAGGCCCAAGAGGGCCACCTGGGGACACAGGGAAAGATGGCCCCCGTGGAAT GCCAGGAGTACCCGGTGAACCAGGAAAGCCAGGAGAACAAGGCTTGATGGGTCCTCTAGGGCCTCCGGGACAAAAGGGTTCTATTGGAGC ACCTGGAATTCCAGGGATGAATGGGCAAAAGGGTGAGCCCGGGTTGCCTGGAGCAGTAGGACAGAATGGAATACCAGGACCTAAGGGAGA ACCTGGAGAACAAGGTGAAAAGGGAGACGCTGGAGAGAACGGCCCCAAGGGTGACACAGGCGAAAAGGGTGACCCTGGATCATCTGCTGC AGGAATTAAGGGAGAACCTGGGGAATCTGGTCGTCCAGGGCAAAAGGGTGAACCAGGGCTTCCTGGGCTTCCTGGACTTCCGGGGATAAA GGGAGAACCAGGTTTCATTGGTCCTCAAGGAGAACCAGGCTTACCAGGTTTACCAGGAACAAAAGGTGAACGGGGGGAAGCAGGGCCTCC TGGAAGAGGTGAGCGAGGGGAACCTGGAGCCCCCGGACCAAAGGGGAAACAAGGTGAATCAGGAACTAGAGGCCCAAAGGGGTCAAAGGG GGATCGTGGAGAAAAAGGGGACTCTGGAGCTCAGGGACCAAGGGGTCCACCTGGTCAAAAAGGGGATCAAGGAGCCACTGAGATCATAGA CTACAACGGCAACCTCCACGAAGCCTTACAGAGGATTACCACCTTAACTGTCACGGGTCCCCCTGGACCTCCTGGACCTCAAGGACTACA AGGGCCAAAGGGAGAGCAGGGATCTCCAGGAATCCCAGGAATGGATGGAGAGCAGGGACTCAAAGGCTCAAAGGGAGACATGGGGGACCC AGGTATGACAGGTGAAAAAGGAGGAATTGGACTTCCTGGATTACCGGGAGCCAATGGAATGAAAGGAGAAAAAGGAGATTCTGGAATGCC GGGTCCACAGGGTCCTTCTATCATAGGCCCACCAGGCCCACCAGGTCCCCATGGCCCACCTGGCCCCATGGGACCTCATGGACTTCCTGG ACCAAAGGGTACAGATGGTCCTATGGGACCCCATGGCCCTGCAGGTCCCAAAGGAGAAAGAGGTGAAAAAGGAGCTATGGGAGAGCCTGG ACCAAGAGGGCCCTATGGGCTGCCTGGGAAAGATGGAGAGCCTGGTCTTGATGGCTTCCCTGGTCCACGGGGTGAGAAGGGTGATCTAGG AGAAAAGGGAGAAAAGGTGACCTCTCCATCCCAGCATGTACCTTGTTTGATTCTTCTCCTGCTGTCTGCTTTGCTGTTCAGCTTGTGTGA TTCCATTTGACACTTAATCTTTCTCCATCCTGTGCTCCAAAAACATACTGATGCCTGATTTAAGGAATCAGGTCTTCAGAGAGGAATGAA GAAGGCTGTACTGCCAGATATAAGGGCACTGCCTGGCATAGAAGAAAAAATTATTATCACCAGATATTCTAGCTACAGTTTTTCAACCAC >In-frame_PPP3CA_ENST00000523694_chr4_102267896_-_COL25A1_ENST00000399132_chr4_109895715_-_1813nt ATGTCCGAGCCCAAGGCAATTGATCCCAAGTTGTCGACGACCGACAGGGTGGTGAAAGGGCCCTCCTGGTCCAAAAGGCGATAAGGGAGA ACAAGGTGATCAGGGACCTAGGATGGTGTTTCCTAAAATCAATCATGGGTTTCTCTCTGCTGATCAGCAGCTCATTAAACGCCGCCTGAT TAAGGGTGACCAAGGACAGGCAGGGCCTCCAGGACCCCCTGGCCCTCCAGGCCCAAGAGGGCCACCTGGGGACACAGGGAAAGATGGCCC CCGTGGAATGCCAGGAGTACCCGGTGAACCAGGAAAGCCAGGAGAACAAGGCTTGATGGGTCCTCTAGGGCCTCCGGGACAAAAGGGTTC TATTGGAGCACCTGGAATTCCAGGGATGAATGGGCAAAAGGGTGAGCCCGGGTTGCCTGGAGCAGTAGGACAGAATGGAATACCAGGACC TAAGGGAGAACCTGGAGAACAAGGTGAAAAGGGAGACGCTGGAGAGAACGGCCCCAAGGGTGACACAGGCGAAAAGGGTGACCCTGGATC ATCTGCTGCAGGAATTAAGGGAGAACCTGGGGAATCTGGTCGTCCAGGGCAAAAGGGTGAACCAGGGCTTCCTGGGCTTCCTGGACTTCC GGGGATAAAGGGAGAACCAGGTTTCATTGGTCCTCAAGGAGAACCAGGCTTACCAGGTTTACCAGGAACAAAAGGTGAACGGGGGGAAGC AGGGCCTCCTGGAAGAGGTGAGCGAGGGGAACCTGGAGCCCCCGGACCAAAGGGGAAACAAGGTGAATCAGGAACTAGAGGCCCAAAGGG GTCAAAGGGGGATCGTGGAGAAAAAGGGGACTCTGGAGCTCAGGGACCAAGGGGTCCACCTGGTCAAAAAGGGGATCAAGGAGCCACTGA GATCATAGACTACAACGGCAACCTCCACGAAGCCTTACAGAGGATTACCACCTTAACTGTCACGGGTCCCCCTGGACCTCCTGGACCTCA AGGACTACAAGGGCCAAAGGGAGAGCAGGGATCTCCAGGAATCCCAGGAATGGATGGAGAGCAGGGACTCAAAGGCTCAAAGGGAGACAT GGGGGACCCAGGTATGACAGGTGAAAAAGGAGGAATTGGACTTCCTGGATTACCGGGAGCCAATGGAATGAAAGGAGAAAAAGGAGATTC TGGAATGCCGGGTCCACAGGGTCCTTCTATCATAGGCCCACCAGGCCCACCAGGTCCCCATGGCCCACCTGGCCCCATGGGACCTCATGG ACTTCCTGGACCAAAGGGTACAGATGGTCCTATGGGACCCCATGGCCCTGCAGGTCCCAAAGGAGAAAGAGGTGAAAAAGGAGCTATGGG AGAGCCTGGACCAAGAGGGCCCTATGGGCTGCCTGGGAAAGATGGAGAGCCTGGTCTTGATGGCTTCCCTGGTCCACGGGGTGAGAAGGG TGATCTAGGAGAAAAGGGAGAAAAGGGATTCCGTGGCGTTAAGGGGGAAAAAGGGGAGCCAGGCCAGCCTGGCCTGGATGGGCTGGATGC CCCTTGCCAATTGGGGCCAGATGGCTTACCCATGCCTGGCTGTTGGCAAAAGTGATGAATCTAACCTTTCAAGCATGAAGTTGTGTATAT AAGGGTCCATTTTTAATATTTATAGTTGAAAACTGAATTGCAGATTTTACAAGTCTGAGATATGTTTACATAGGGCTGCTTCTTCCTGCT GGCAGTAGTATACATGTCCATTTTTACTCCACTTACATCTGAAATTGGGCAATTTGTGAAACCAGTGAGAATCCTGCAAAAAATATAGAT >In-frame_PPP3CA_ENST00000523694_chr4_102267896_-_COL25A1_ENST00000399127_chr4_109895715_-_1772nt ATGTCCGAGCCCAAGGCAATTGATCCCAAGTTGTCGACGACCGACAGGGTGGTGAAAGGGCCCTCCTGGTCCAAAAGGCGATAAGGGAGA ACAAGGTGATCAGGGACCTAGGGGCCTGCCAGGCTTCCCCACAGTTGCTGCCCTGCACAGTAATCAGATCCTCACCGTCAAGGGTGACCA AGGACAGGCAGGGCCTCCAGGACCCCCTGGCCCTCCAGGCCCAAGAGGGCCACCTGGGGACACAGGGAAAGATGGCCCCCGTGGAATGCC AGGAGTACCCGGTGAACCAGGAAAGCCAGGAGAACAAGGCTTGATGGGTCCTCTAGGGCCTCCGGGACAAAAGGGTTCTATTGGAGCACC TGGAATTCCAGGGATGAATGGGCAAAAGGGTGAGCCCGGGTTGCCTGGAGCAGTAGGACAGAATGGAATACCAGGACCTAAGGGAGAACC TGGAGAACAAGGTGAAAAGGGAGACGCTGGAGAGAACGGCCCCAAGGGTGACACAGGCGAAAAGGGTGACCCTGGATCATCTGCTGCAGG AATTAAGGGAGAACCTGGGGAATCTGGTCGTCCAGGGCAAAAGGGTGAACCAGGGCTTCCTGGGCTTCCTGGACTTCCGGGGATAAAGGG AGAACCAGGTTTCATTGGTCCTCAAGGAGAACCAGGCTTACCAGGTTTACCAGGAACAAAAGGTGAACGGGGGGAAGCAGGGCCTCCTGG AAGAGGTGAGCGAGGGGAACCTGGAGCCCCCGGACCAAAGGGGGATCGTGGAGAAAAAGGGGACTCTGGAGCTCAGGGACCAAGGGGTCC ACCTGGTCAAAAAGGGGATCAAGGAGCCACTGAGATCATAGACTACAACGGCAACCTCCACGAAGCCTTACAGGGTCCCCCTGGACCTCC TGGACCTCAAGGACTACAAGGGCCAAAGGGAGAGCAGGGATCTCCAGGAATCCCAGGAATGGATGGAGAGCAGGGACTCAAAGGCTCAAA GGGAGACATGGGGGACCCAGGTATGACAGGTGAAAAAGGAGGAATTGGACTTCCTGGATTACCGGGAGCCAATGGAATGAAAGGAGAAAA AGGAGATTCTGGAATGCCGGGTCCACAGGGTCCTTCTATCATAGGCCCACCAGGCCCACCAGGTCCCCATGGCCCACCTGGCCCCATGGG ACCTCATGGACTTCCTGGACCAAAGGGTGAACCAGGGTTAAATGGTGTTAAAGGATTGAAGGGTGAACCAGGTCAAAAGGGTGACAGAGG ACCCCTTGGTCTTCCAGGAGCATCTGGCTTAGACGGAAAGCCAGGATCCCGGGGTACAGATGGTCCTATGGGACCCCATGGCCCTGCAGG TCCCAAAGGAGAAAGAGGTGAAAAAGGAGCTATGGGAGAGCCTGGACCAAGAGGGCCCTATGGGCTGCCTGGCTTCCCTGGTCCACGGGG TGAGAAGGGTGATCTAGGAGAAAAGGGAGAAAAGGTGACCTCTCCATCCCAGCATGTACCTTGTTTGATTCTTCTCCTGCTGTCTGCTTT GCTGTTCAGCTTGTGTGATTCCATTTGACACTTAATCTTTCTCCATCCTGTGCTCCAAAAACATACTGATGCCTGATTTAAGGAATCAGG TCTTCAGAGAGGAATGAAGAAGGCTGTACTGCCAGATATAAGGGCACTGCCTGGCATAGAAGAAAAAATTATTATCACCAGATATTCTAG >In-frame_PPP3CA_ENST00000523694_chr4_102267896_-_COL25A1_ENST00000399126_chr4_109895715_-_1763nt ATGTCCGAGCCCAAGGCAATTGATCCCAAGTTGTCGACGACCGACAGGGTGGTGAAAGGGCCCTCCTGGTCCAAAAGGCGATAAGGGAGA ACAAGGTGATCAGGGACCTAGGATGGTGTTTCCTAAAATCAATCATGGGTTTCTCTCTGCTGATCAGCAGCTCATTAAACGCCGCCTGAT TAAGGGTGACCAAGGACAGGCAGGGCCTCCAGGACCCCCTGGCCCTCCAGGCCCAAGAGGGCCACCTGGGGACACAGGGAAAGATGGCCC CCGTGGAATGCCAGGAGTACCCGGTGAACCAGGAAAGCCAGGAGAACAAGGCTTGATGGGTCCTCTAGGGCCTCCGGGACAAAAGGGTTC TATTGGAGCACCTGGAATTCCAGGGATGAATGGGCAAAAGGGTGAGCCCGGGTTGCCTGGAGCAGTAGGACAGAATGGAATACCAGGACC TAAGGGAGAACCTGGAGAACAAGGTGAAAAGGGAGACGCTGGAGAGAACGGCCCCAAGGGTGACACAGGCGAAAAGGGTGACCCTGGATC ATCTGCTGCAGGAATTAAGGGAGAACCTGGGGAATCTGGTCGTCCAGGGCAAAAGGGTGAACCAGGGCTTCCTGGGCTTCCTGGACTTCC GGGGATAAAGGGAGAACCAGGTTTCATTGGTCCTCAAGGAGAACCAGGCTTACCAGGTTTACCAGGAACAAAAGGTGAACGGGGGGAAGC AGGGCCTCCTGGAAGAGGTGAGCGAGGGGAACCTGGAGCCCCCGGACCAAAGGGGAAACAAGGTGAATCAGGAACTAGAGGCCCAAAGGG GTCAAAGGGGGATCGTGGAGAAAAAGGGGACTCTGGAGCTCAGGGACCAAGGGGTCCACCTGGTCAAAAAGGGGATCAAGGAGCCACTGA GATCATAGACTACAACGGCAACCTCCACGAAGCCTTACAGAGGATTACCACCTTAACTGTCACGGGTCCCCCTGGACCTCCTGGACCTCA AGGACTACAAGGGCCAAAGGGAGAGCAGGGATCTCCAGGAATCCCAGGAATGGATGGAGAGCAGGGACTCAAAGGCTCAAAGGGAGACAT GGGGGACCCAGGTATGACAGGTGAAAAAGGAGGAATTGGACTTCCTGGATTACCGGGAGCCAATGGAATGAAAGGAGAAAAAGGAGATTC TGGAATGCCGGGTCCACAGGGTCCTTCTATCATAGGCCCACCAGGCCCACCAGGTCCCCATGGCCCACCTGGCCCCATGGGACCTCATGG ACTTCCTGGACCAAAGGGTACAGATGGTCCTATGGGACCCCATGGCCCTGCAGGTCCCAAAGGAGAAAGAGGTGAAAAAGGAGCTATGGG AGAGCCTGGACCAAGAGGGCCCTATGGGCTGCCTGGGAAAGATGGAGAGCCTGGTCTTGATGGCTTCCCTGGTCCACGGGGTGAGAAGGG TGATCTAGGAGAAAAGGGAGAAAAGGTGACCTCTCCATCCCAGCATGTACCTTGTTTGATTCTTCTCCTGCTGTCTGCTTTGCTGTTCAG CTTGTGTGATTCCATTTGACACTTAATCTTTCTCCATCCTGTGCTCCAAAAACATACTGATGCCTGATTTAAGGAATCAGGTCTTCAGAG AGGAATGAAGAAGGCTGTACTGCCAGATATAAGGGCACTGCCTGGCATAGAAGAAAAAATTATTATCACCAGATATTCTAGCTACAGTTT |
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FusionGenePPI for PPP3CA_COL25A1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| PPP3CA | C16orf74, PPIA, RCAN1, ADRB2, RCAN2, AKAP5, BCL2, CABIN1, MYOZ2, MYOZ1, IRF2, GRB2, AKT1, PHLPP2, PTEN, PSMA6, PDE4D, KCNIP3, TRAF3, PPP3R1, MRI1, RHOC, MAPK7, HNRNPH1, P3H1, SETSIP, MAT2B, NASP, NRD1, PDIA6, PFDN5, PPP2R2A, TNPO3, TNPO1, TSN, VBP1, XPO5, MARCH7, CEP76, TP53, VCP, JUN, FAM122A, RASSF2, PDHB, RCAN3, NFATC4, SIK3, ARFIP1, C6orf211, PSMD9, CRTC2, LBH, NCAPG, TUBA1B, DEFA1, TMEM200A, SMPD3, NFATC1, KLRG2, AATK, FGFR4, RYK, PTK7 | COL25A1 | APP, COL25A1, PLOD1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | PPP3CA | chr4:102267896 | chr4:109895715 | ENST00000323055 | - | 1 | 12 | 327_336 | 19 | 470 | PxIxIF motif in substrate |
| Hgene | PPP3CA | chr4:102267896 | chr4:109895715 | ENST00000394853 | - | 1 | 13 | 327_336 | 19 | 512 | PxIxIF motif in substrate |
| Hgene | PPP3CA | chr4:102267896 | chr4:109895715 | ENST00000394854 | - | 1 | 14 | 327_336 | 19 | 522 | PxIxIF motif in substrate |
| Hgene | PPP3CA | chr4:102267896 | chr4:109895715 | ENST00000512215 | - | 1 | 8 | 327_336 | 19 | 290 | PxIxIF motif in substrate |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for PPP3CA_COL25A1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for PPP3CA_COL25A1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | PPP3CA | C0019202 | Hepatolenticular Degeneration | 1 | CTD_human |
| Hgene | PPP3CA | C0030305 | Pancreatitis | 1 | CTD_human |
| Hgene | PPP3CA | C0033578 | Prostatic Neoplasms | 1 | CTD_human |
| Hgene | PPP3CA | C0039584 | Testicular Diseases | 1 | CTD_human |
| Hgene | PPP3CA | C0149721 | Left Ventricular Hypertrophy | 1 | CTD_human |
| Hgene | PPP3CA | C0152013 | Adenocarcinoma of lung (disorder) | 1 | CTD_human |
| Tgene | COL25A1 | C4015552 | FIBROSIS OF EXTRAOCULAR MUSCLES, CONGENITAL, 5 | 1 | UNIPROT |
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