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Fusion gene ID: 28417 |
FusionGeneSummary for PPP2R2A_DHTKD1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PPP2R2A_DHTKD1 | Fusion gene ID: 28417 | Hgene | Tgene | Gene symbol | PPP2R2A | DHTKD1 | Gene ID | 5520 | 55526 |
| Gene name | protein phosphatase 2 regulatory subunit Balpha | dehydrogenase E1 and transketolase domain containing 1 | |
| Synonyms | B55A|B55ALPHA|PR52A|PR55A|PR55alpha | AMOXAD|CMT2Q | |
| Cytomap | 8p21.2 | 10p14 | |
| Type of gene | protein-coding | protein-coding | |
| Description | serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoformprotein phosphatase 2, regulatory subunit B, alpha | probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrialdehydrogenase E1 and transketolase domain-containing protein 1 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | P63151 | Q96HY7 | |
| Ensembl transtripts involved in fusion gene | ENST00000380737, ENST00000315985, ENST00000523473, | ENST00000263035, ENST00000465617, | |
| Fusion gene scores | * DoF score | 15 X 9 X 8=1080 | 4 X 4 X 2=32 |
| # samples | 21 | 4 | |
| ** MAII score | log2(21/1080*10)=-2.36257007938471 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(4/32*10)=0.321928094887362 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: PPP2R2A [Title/Abstract] AND DHTKD1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | PPP2R2A | GO:0006470 | protein dephosphorylation | 1849734 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | OV | TCGA-24-2288-01A | PPP2R2A | chr8 | 26151256 | + | DHTKD1 | chr10 | 12123471 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000380737 | ENST00000263035 | PPP2R2A | chr8 | 26151256 | + | DHTKD1 | chr10 | 12123471 | + |
| 5CDS-intron | ENST00000380737 | ENST00000465617 | PPP2R2A | chr8 | 26151256 | + | DHTKD1 | chr10 | 12123471 | + |
| In-frame | ENST00000315985 | ENST00000263035 | PPP2R2A | chr8 | 26151256 | + | DHTKD1 | chr10 | 12123471 | + |
| 5CDS-intron | ENST00000315985 | ENST00000465617 | PPP2R2A | chr8 | 26151256 | + | DHTKD1 | chr10 | 12123471 | + |
| 3UTR-3CDS | ENST00000523473 | ENST00000263035 | PPP2R2A | chr8 | 26151256 | + | DHTKD1 | chr10 | 12123471 | + |
| 3UTR-intron | ENST00000523473 | ENST00000465617 | PPP2R2A | chr8 | 26151256 | + | DHTKD1 | chr10 | 12123471 | + |
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FusionProtFeatures for PPP2R2A_DHTKD1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| PPP2R2A | DHTKD1 |
| The B regulatory subunit might modulate substrateselectivity and catalytic activity, and also might direct thelocalization of the catalytic enzyme to a particular subcellularcompartment. | The 2-oxoglutarate dehydrogenase complex catalyzes theoverall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). Itcontains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamidesuccinyltransferase (E2) and lipoamide dehydrogenase (E3) (Bysimilarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >PPP2R2A | chr8:26151256 | chr10:12123471 | ENST00000315985 | + | 2 | 10 | 175_213 | 37 | 458 | Repeat | Note=WD 3 |
| Hgene | >PPP2R2A | chr8:26151256 | chr10:12123471 | ENST00000315985 | + | 2 | 10 | 224_264 | 37 | 458 | Repeat | Note=WD 4 |
| Hgene | >PPP2R2A | chr8:26151256 | chr10:12123471 | ENST00000315985 | + | 2 | 10 | 26_65 | 37 | 458 | Repeat | Note=WD 1 |
| Hgene | >PPP2R2A | chr8:26151256 | chr10:12123471 | ENST00000315985 | + | 2 | 10 | 283_321 | 37 | 458 | Repeat | Note=WD 5 |
| Hgene | >PPP2R2A | chr8:26151256 | chr10:12123471 | ENST00000315985 | + | 2 | 10 | 338_379 | 37 | 458 | Repeat | Note=WD 6 |
| Hgene | >PPP2R2A | chr8:26151256 | chr10:12123471 | ENST00000315985 | + | 2 | 10 | 414_446 | 37 | 458 | Repeat | Note=WD 7 |
| Hgene | >PPP2R2A | chr8:26151256 | chr10:12123471 | ENST00000315985 | + | 2 | 10 | 91_132 | 37 | 458 | Repeat | Note=WD 2 |
| Hgene | >PPP2R2A | chr8:26151256 | chr10:12123471 | ENST00000380737 | + | 2 | 10 | 175_213 | 27 | 448 | Repeat | Note=WD 3 |
| Hgene | >PPP2R2A | chr8:26151256 | chr10:12123471 | ENST00000380737 | + | 2 | 10 | 224_264 | 27 | 448 | Repeat | Note=WD 4 |
| Hgene | >PPP2R2A | chr8:26151256 | chr10:12123471 | ENST00000380737 | + | 2 | 10 | 26_65 | 27 | 448 | Repeat | Note=WD 1 |
| Hgene | >PPP2R2A | chr8:26151256 | chr10:12123471 | ENST00000380737 | + | 2 | 10 | 283_321 | 27 | 448 | Repeat | Note=WD 5 |
| Hgene | >PPP2R2A | chr8:26151256 | chr10:12123471 | ENST00000380737 | + | 2 | 10 | 338_379 | 27 | 448 | Repeat | Note=WD 6 |
| Hgene | >PPP2R2A | chr8:26151256 | chr10:12123471 | ENST00000380737 | + | 2 | 10 | 414_446 | 27 | 448 | Repeat | Note=WD 7 |
| Hgene | >PPP2R2A | chr8:26151256 | chr10:12123471 | ENST00000380737 | + | 2 | 10 | 91_132 | 27 | 448 | Repeat | Note=WD 2 |
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FusionGeneSequence for PPP2R2A_DHTKD1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_PPP2R2A_ENST00000380737_chr8_26151256_+_DHTKD1_ENST00000263035_chr10_12123471_+_896aa MAGAGGGNDIQWCFSQVKGAVDDDVAEVDHGLARLVTVYCEHGHKAAKINPLFTGQALLENVPEIQALVQTLQGPFHTAGLLNMGKEEAS LEEVLVYLNQIYCGQISIETSQLQSQDEKDWFAKRFEELQKETFTTEERKHLSKLMLESQEFDHFLATKFSTVKRYGGEGAESMMGFFHE LLKMSAYSGITDVIIGMPHRGRLNLLTGLLQFPPELMFRKMRGLSEFPENFSATGDVLSHLTSSVDLYFGAHHPLHVTMLPNPSHLEAVN PVAVGKTRGRQQSRQDGDYSPDNSAQPGDRVICLQVHGDASFCGQGIVPETFTLSNLPHFRIGGSVHLIVNNQLGYTTPAERGRSSLYCS DIGKLVGCAIIHVNGDSPEEVVRATRLAFEYQRQFRKDVIIDLLCYRQWGHNELDEPFYTNPIMYKIIRARKSIPDTYAEHLIAGGLMTQ EEVSEIKSSYYAKLNDHLNNMAHYRPPALNLQAHWQGLAQPEAQITTWSTGVPLDLLRFVGMKSVEVPRELQMHSHLLKTHVQSRMEKMM DGIKLDWATAEALALGSLLAQGFNVRLSGQDVGRGTFSQRHAIVVCQETDDTYIPLNHMDPNQKGFLEVSNSPLSEEAVLGFEYGMSIES PKLLPLWEAQFGDFFNGAQIIFDTFISGGEAKWLLQSGIVILLPHGYDGAGPDHSSCRIERFLQMCDSAEEGVDGDTVNMFVVHPTTPAQ YFHLLRRQMVRNFRKPLIVASPKMLLRLPAAVSTLQEMAPGTTFNPVIGDSSVDPKKVKTLVFCSGKHFYSLVKQRESLGAKKHDFAIIR >In-frame_PPP2R2A_ENST00000315985_chr8_26151256_+_DHTKD1_ENST00000263035_chr10_12123471_+_906aa MFPKFSLRSMFHGAGGGNDIQWCFSQVKGAVDDDVAEVDHGLARLVTVYCEHGHKAAKINPLFTGQALLENVPEIQALVQTLQGPFHTAG LLNMGKEEASLEEVLVYLNQIYCGQISIETSQLQSQDEKDWFAKRFEELQKETFTTEERKHLSKLMLESQEFDHFLATKFSTVKRYGGEG AESMMGFFHELLKMSAYSGITDVIIGMPHRGRLNLLTGLLQFPPELMFRKMRGLSEFPENFSATGDVLSHLTSSVDLYFGAHHPLHVTML PNPSHLEAVNPVAVGKTRGRQQSRQDGDYSPDNSAQPGDRVICLQVHGDASFCGQGIVPETFTLSNLPHFRIGGSVHLIVNNQLGYTTPA ERGRSSLYCSDIGKLVGCAIIHVNGDSPEEVVRATRLAFEYQRQFRKDVIIDLLCYRQWGHNELDEPFYTNPIMYKIIRARKSIPDTYAE HLIAGGLMTQEEVSEIKSSYYAKLNDHLNNMAHYRPPALNLQAHWQGLAQPEAQITTWSTGVPLDLLRFVGMKSVEVPRELQMHSHLLKT HVQSRMEKMMDGIKLDWATAEALALGSLLAQGFNVRLSGQDVGRGTFSQRHAIVVCQETDDTYIPLNHMDPNQKGFLEVSNSPLSEEAVL GFEYGMSIESPKLLPLWEAQFGDFFNGAQIIFDTFISGGEAKWLLQSGIVILLPHGYDGAGPDHSSCRIERFLQMCDSAEEGVDGDTVNM FVVHPTTPAQYFHLLRRQMVRNFRKPLIVASPKMLLRLPAAVSTLQEMAPGTTFNPVIGDSSVDPKKVKTLVFCSGKHFYSLVKQRESLG AKKHDFAIIRVEELCPFPLDSLQQEMSKYKHVKDHIWSQEEPQNMGPWSFVSPRFEKQLACKLRLVGRPPLPVPAVGIGTVHLHQHEDIL |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_PPP2R2A_ENST00000380737_chr8_26151256_+_DHTKD1_ENST00000263035_chr10_12123471_+_2688nt ATGGCAGGAGCTGGAGGAGGGAATGATATTCAGTGGTGTTTTTCTCAGGTGAAAGGAGCAGTAGATGATGATGTAGCAGAAGTTGATCAT GGCCTTGCCAGGTTGGTGACAGTATATTGTGAGCATGGTCATAAAGCTGCCAAAATCAACCCCCTCTTCACCGGACAAGCCCTGCTGGAG AATGTGCCTGAAATCCAAGCCCTGGTGCAGACACTGCAGGGACCCTTCCACACGGCAGGATTATTGAACATGGGGAAGGAAGAGGCCTCA CTTGAGGAAGTGTTAGTCTATCTCAATCAAATCTACTGTGGGCAGATTTCTATTGAAACCTCCCAACTTCAGAGCCAGGATGAGAAAGAC TGGTTTGCCAAGCGGTTTGAGGAACTGCAAAAGGAGACGTTTACCACAGAAGAGCGAAAACATCTGTCGAAACTAATGCTGGAATCTCAG GAGTTTGACCACTTTCTGGCCACCAAGTTCTCGACAGTGAAGCGATATGGAGGCGAAGGGGCTGAAAGCATGATGGGCTTTTTCCACGAG CTGCTGAAAATGTCGGCCTACAGCGGGATCACTGATGTCATTATTGGGATGCCCCATAGAGGGAGGCTGAATTTATTGACAGGCCTTCTG CAGTTCCCTCCAGAGCTGATGTTCCGTAAAATGCGAGGCTTAAGTGAATTTCCAGAGAATTTCTCAGCCACTGGAGACGTCCTGTCTCAC CTGACCTCCTCTGTGGACCTGTACTTTGGGGCGCACCATCCCCTCCATGTGACAATGTTGCCCAATCCCTCGCACCTGGAGGCCGTCAAC CCCGTGGCCGTGGGCAAAACTCGCGGCAGGCAGCAGTCTCGCCAAGACGGCGATTACTCTCCAGACAACTCAGCCCAGCCGGGGGACAGG GTCATTTGCTTACAGGTCCATGGTGATGCTTCTTTCTGTGGTCAAGGGATTGTTCCTGAAACATTCACGCTGTCCAATCTCCCACATTTC AGAATTGGTGGGAGTGTGCATTTGATTGTTAATAACCAGCTGGGTTACACCACTCCAGCTGAAAGAGGAAGGTCTTCTTTATACTGCAGT GATATTGGGAAGCTTGTGGGCTGTGCCATCATCCATGTCAATGGAGACAGCCCAGAGGAAGTGGTCCGTGCCACACGACTGGCTTTTGAA TACCAACGCCAGTTCCGCAAGGATGTGATTATTGATCTGTTGTGCTACAGGCAGTGGGGCCACAATGAGCTGGATGAGCCATTCTACACC AACCCCATCATGTACAAAATCATCAGAGCTCGAAAGAGCATTCCAGACACATATGCAGAGCACCTCATTGCTGGCGGACTCATGACGCAG GAGGAGGTGTCTGAAATAAAATCCTCCTACTATGCCAAGTTGAATGATCACTTAAATAACATGGCCCACTACAGGCCCCCTGCCCTGAAC CTGCAGGCCCACTGGCAGGGCCTGGCTCAGCCAGAAGCGCAAATCACCACCTGGAGTACAGGTGTGCCCCTCGACCTCCTGCGGTTTGTT GGCATGAAGTCTGTAGAGGTGCCAAGAGAGCTGCAGATGCACAGTCACCTGCTGAAGACACATGTTCAGTCCAGAATGGAGAAGATGATG GACGGAATCAAGCTAGACTGGGCCACCGCGGAAGCTCTTGCCTTGGGTTCTTTACTTGCTCAAGGTTTTAATGTTCGTCTAAGTGGCCAA GATGTTGGTCGTGGAACTTTCAGTCAGAGGCATGCAATCGTGGTTTGCCAGGAGACGGATGACACCTACATCCCCCTGAACCATATGGAC CCAAATCAGAAGGGGTTTCTAGAGGTCAGCAACAGCCCACTGTCAGAAGAGGCCGTCCTGGGATTTGAATATGGGATGAGCATTGAGAGC CCAAAGTTACTGCCCCTGTGGGAGGCACAGTTTGGCGATTTCTTCAATGGTGCCCAGATCATCTTTGACACATTCATCTCTGGAGGAGAG GCCAAGTGGCTCCTACAAAGCGGCATCGTCATCCTCCTTCCACATGGCTACGATGGGGCTGGGCCAGACCACTCATCCTGTCGAATAGAG CGTTTCCTGCAGATGTGTGACAGTGCGGAAGAGGGGGTGGACGGAGACACTGTGAACATGTTTGTGGTTCACCCAACAACTCCTGCACAG TATTTCCACTTGCTTAGGAGACAGATGGTCCGGAACTTCAGAAAACCACTCATTGTTGCTTCCCCTAAGATGTTACTCAGGCTCCCGGCA GCCGTGTCAACTCTTCAAGAAATGGCACCAGGAACAACATTTAACCCGGTCATTGGTGATTCATCTGTGGATCCAAAAAAGGTTAAGACC CTCGTGTTCTGCTCCGGCAAACATTTCTACTCCCTGGTGAAACAAAGAGAATCTCTGGGGGCCAAGAAGCATGACTTTGCCATCATCCGA GTAGAGGAACTCTGCCCCTTCCCGTTGGATTCTTTACAGCAAGAGATGAGCAAATACAAACATGTTAAAGATCATATTTGGAGTCAGGAG GAACCTCAGAACATGGGTCCGTGGTCGTTTGTTTCTCCAAGGTTTGAAAAGCAGCTGGCCTGCAAGCTCCGTCTGGTGGGCCGGCCCCCT >In-frame_PPP2R2A_ENST00000315985_chr8_26151256_+_DHTKD1_ENST00000263035_chr10_12123471_+_2718nt ATGTTCCCGAAGTTTTCTCTTCGTTCTATGTTTCATGGAGCTGGAGGAGGGAATGATATTCAGTGGTGTTTTTCTCAGGTGAAAGGAGCA GTAGATGATGATGTAGCAGAAGTTGATCATGGCCTTGCCAGGTTGGTGACAGTATATTGTGAGCATGGTCATAAAGCTGCCAAAATCAAC CCCCTCTTCACCGGACAAGCCCTGCTGGAGAATGTGCCTGAAATCCAAGCCCTGGTGCAGACACTGCAGGGACCCTTCCACACGGCAGGA TTATTGAACATGGGGAAGGAAGAGGCCTCACTTGAGGAAGTGTTAGTCTATCTCAATCAAATCTACTGTGGGCAGATTTCTATTGAAACC TCCCAACTTCAGAGCCAGGATGAGAAAGACTGGTTTGCCAAGCGGTTTGAGGAACTGCAAAAGGAGACGTTTACCACAGAAGAGCGAAAA CATCTGTCGAAACTAATGCTGGAATCTCAGGAGTTTGACCACTTTCTGGCCACCAAGTTCTCGACAGTGAAGCGATATGGAGGCGAAGGG GCTGAAAGCATGATGGGCTTTTTCCACGAGCTGCTGAAAATGTCGGCCTACAGCGGGATCACTGATGTCATTATTGGGATGCCCCATAGA GGGAGGCTGAATTTATTGACAGGCCTTCTGCAGTTCCCTCCAGAGCTGATGTTCCGTAAAATGCGAGGCTTAAGTGAATTTCCAGAGAAT TTCTCAGCCACTGGAGACGTCCTGTCTCACCTGACCTCCTCTGTGGACCTGTACTTTGGGGCGCACCATCCCCTCCATGTGACAATGTTG CCCAATCCCTCGCACCTGGAGGCCGTCAACCCCGTGGCCGTGGGCAAAACTCGCGGCAGGCAGCAGTCTCGCCAAGACGGCGATTACTCT CCAGACAACTCAGCCCAGCCGGGGGACAGGGTCATTTGCTTACAGGTCCATGGTGATGCTTCTTTCTGTGGTCAAGGGATTGTTCCTGAA ACATTCACGCTGTCCAATCTCCCACATTTCAGAATTGGTGGGAGTGTGCATTTGATTGTTAATAACCAGCTGGGTTACACCACTCCAGCT GAAAGAGGAAGGTCTTCTTTATACTGCAGTGATATTGGGAAGCTTGTGGGCTGTGCCATCATCCATGTCAATGGAGACAGCCCAGAGGAA GTGGTCCGTGCCACACGACTGGCTTTTGAATACCAACGCCAGTTCCGCAAGGATGTGATTATTGATCTGTTGTGCTACAGGCAGTGGGGC CACAATGAGCTGGATGAGCCATTCTACACCAACCCCATCATGTACAAAATCATCAGAGCTCGAAAGAGCATTCCAGACACATATGCAGAG CACCTCATTGCTGGCGGACTCATGACGCAGGAGGAGGTGTCTGAAATAAAATCCTCCTACTATGCCAAGTTGAATGATCACTTAAATAAC ATGGCCCACTACAGGCCCCCTGCCCTGAACCTGCAGGCCCACTGGCAGGGCCTGGCTCAGCCAGAAGCGCAAATCACCACCTGGAGTACA GGTGTGCCCCTCGACCTCCTGCGGTTTGTTGGCATGAAGTCTGTAGAGGTGCCAAGAGAGCTGCAGATGCACAGTCACCTGCTGAAGACA CATGTTCAGTCCAGAATGGAGAAGATGATGGACGGAATCAAGCTAGACTGGGCCACCGCGGAAGCTCTTGCCTTGGGTTCTTTACTTGCT CAAGGTTTTAATGTTCGTCTAAGTGGCCAAGATGTTGGTCGTGGAACTTTCAGTCAGAGGCATGCAATCGTGGTTTGCCAGGAGACGGAT GACACCTACATCCCCCTGAACCATATGGACCCAAATCAGAAGGGGTTTCTAGAGGTCAGCAACAGCCCACTGTCAGAAGAGGCCGTCCTG GGATTTGAATATGGGATGAGCATTGAGAGCCCAAAGTTACTGCCCCTGTGGGAGGCACAGTTTGGCGATTTCTTCAATGGTGCCCAGATC ATCTTTGACACATTCATCTCTGGAGGAGAGGCCAAGTGGCTCCTACAAAGCGGCATCGTCATCCTCCTTCCACATGGCTACGATGGGGCT GGGCCAGACCACTCATCCTGTCGAATAGAGCGTTTCCTGCAGATGTGTGACAGTGCGGAAGAGGGGGTGGACGGAGACACTGTGAACATG TTTGTGGTTCACCCAACAACTCCTGCACAGTATTTCCACTTGCTTAGGAGACAGATGGTCCGGAACTTCAGAAAACCACTCATTGTTGCT TCCCCTAAGATGTTACTCAGGCTCCCGGCAGCCGTGTCAACTCTTCAAGAAATGGCACCAGGAACAACATTTAACCCGGTCATTGGTGAT TCATCTGTGGATCCAAAAAAGGTTAAGACCCTCGTGTTCTGCTCCGGCAAACATTTCTACTCCCTGGTGAAACAAAGAGAATCTCTGGGG GCCAAGAAGCATGACTTTGCCATCATCCGAGTAGAGGAACTCTGCCCCTTCCCGTTGGATTCTTTACAGCAAGAGATGAGCAAATACAAA CATGTTAAAGATCATATTTGGAGTCAGGAGGAACCTCAGAACATGGGTCCGTGGTCGTTTGTTTCTCCAAGGTTTGAAAAGCAGCTGGCC TGCAAGCTCCGTCTGGTGGGCCGGCCCCCTTTGCCAGTACCCGCTGTAGGAATTGGCACAGTTCACTTGCACCAGCATGAAGATATCCTC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_PPP2R2A_ENST00000380737_chr8_26151256_+_DHTKD1_ENST00000263035_chr10_12123471_+_5354nt AGGTGACGTCACTGGCCAGGCCAGCCGGCGCCATTTTGAAAGTGGAGTCGCCTGCCCCTGCCGCTGCCGCCGCCGCCGTCGCTGTCGTAG TCGCCGCCGCCGCTGCCGGAGAAAGAGCACGAGCGGGGAAGCCCCAGAGTGAAATCTAGCATCCTGCCGGCTGGTCTGCCCGCCCCTCCT TCCTTTTCCCCCCGGCCCCCGTCCCCTCCCCCCGCAGGTGCCATCCGCCGCCATCCGCCCTCTCTACCCCCCCATCCCCAGGTGAGGGGG GTGAGTTCAGGAAGCGGAGACCCCGAGGAACCCAGCAGGGTCACCATTTGCAGCGCAACATGGCAGGAGCTGGAGGAGGGAATGATATTC AGTGGTGTTTTTCTCAGGTGAAAGGAGCAGTAGATGATGATGTAGCAGAAGTTGATCATGGCCTTGCCAGGTTGGTGACAGTATATTGTG AGCATGGTCATAAAGCTGCCAAAATCAACCCCCTCTTCACCGGACAAGCCCTGCTGGAGAATGTGCCTGAAATCCAAGCCCTGGTGCAGA CACTGCAGGGACCCTTCCACACGGCAGGATTATTGAACATGGGGAAGGAAGAGGCCTCACTTGAGGAAGTGTTAGTCTATCTCAATCAAA TCTACTGTGGGCAGATTTCTATTGAAACCTCCCAACTTCAGAGCCAGGATGAGAAAGACTGGTTTGCCAAGCGGTTTGAGGAACTGCAAA AGGAGACGTTTACCACAGAAGAGCGAAAACATCTGTCGAAACTAATGCTGGAATCTCAGGAGTTTGACCACTTTCTGGCCACCAAGTTCT CGACAGTGAAGCGATATGGAGGCGAAGGGGCTGAAAGCATGATGGGCTTTTTCCACGAGCTGCTGAAAATGTCGGCCTACAGCGGGATCA CTGATGTCATTATTGGGATGCCCCATAGAGGGAGGCTGAATTTATTGACAGGCCTTCTGCAGTTCCCTCCAGAGCTGATGTTCCGTAAAA TGCGAGGCTTAAGTGAATTTCCAGAGAATTTCTCAGCCACTGGAGACGTCCTGTCTCACCTGACCTCCTCTGTGGACCTGTACTTTGGGG CGCACCATCCCCTCCATGTGACAATGTTGCCCAATCCCTCGCACCTGGAGGCCGTCAACCCCGTGGCCGTGGGCAAAACTCGCGGCAGGC AGCAGTCTCGCCAAGACGGCGATTACTCTCCAGACAACTCAGCCCAGCCGGGGGACAGGGTCATTTGCTTACAGGTCCATGGTGATGCTT CTTTCTGTGGTCAAGGGATTGTTCCTGAAACATTCACGCTGTCCAATCTCCCACATTTCAGAATTGGTGGGAGTGTGCATTTGATTGTTA ATAACCAGCTGGGTTACACCACTCCAGCTGAAAGAGGAAGGTCTTCTTTATACTGCAGTGATATTGGGAAGCTTGTGGGCTGTGCCATCA TCCATGTCAATGGAGACAGCCCAGAGGAAGTGGTCCGTGCCACACGACTGGCTTTTGAATACCAACGCCAGTTCCGCAAGGATGTGATTA TTGATCTGTTGTGCTACAGGCAGTGGGGCCACAATGAGCTGGATGAGCCATTCTACACCAACCCCATCATGTACAAAATCATCAGAGCTC GAAAGAGCATTCCAGACACATATGCAGAGCACCTCATTGCTGGCGGACTCATGACGCAGGAGGAGGTGTCTGAAATAAAATCCTCCTACT ATGCCAAGTTGAATGATCACTTAAATAACATGGCCCACTACAGGCCCCCTGCCCTGAACCTGCAGGCCCACTGGCAGGGCCTGGCTCAGC CAGAAGCGCAAATCACCACCTGGAGTACAGGTGTGCCCCTCGACCTCCTGCGGTTTGTTGGCATGAAGTCTGTAGAGGTGCCAAGAGAGC TGCAGATGCACAGTCACCTGCTGAAGACACATGTTCAGTCCAGAATGGAGAAGATGATGGACGGAATCAAGCTAGACTGGGCCACCGCGG AAGCTCTTGCCTTGGGTTCTTTACTTGCTCAAGGTTTTAATGTTCGTCTAAGTGGCCAAGATGTTGGTCGTGGAACTTTCAGTCAGAGGC ATGCAATCGTGGTTTGCCAGGAGACGGATGACACCTACATCCCCCTGAACCATATGGACCCAAATCAGAAGGGGTTTCTAGAGGTCAGCA ACAGCCCACTGTCAGAAGAGGCCGTCCTGGGATTTGAATATGGGATGAGCATTGAGAGCCCAAAGTTACTGCCCCTGTGGGAGGCACAGT TTGGCGATTTCTTCAATGGTGCCCAGATCATCTTTGACACATTCATCTCTGGAGGAGAGGCCAAGTGGCTCCTACAAAGCGGCATCGTCA TCCTCCTTCCACATGGCTACGATGGGGCTGGGCCAGACCACTCATCCTGTCGAATAGAGCGTTTCCTGCAGATGTGTGACAGTGCGGAAG AGGGGGTGGACGGAGACACTGTGAACATGTTTGTGGTTCACCCAACAACTCCTGCACAGTATTTCCACTTGCTTAGGAGACAGATGGTCC GGAACTTCAGAAAACCACTCATTGTTGCTTCCCCTAAGATGTTACTCAGGCTCCCGGCAGCCGTGTCAACTCTTCAAGAAATGGCACCAG GAACAACATTTAACCCGGTCATTGGTGATTCATCTGTGGATCCAAAAAAGGTTAAGACCCTCGTGTTCTGCTCCGGCAAACATTTCTACT CCCTGGTGAAACAAAGAGAATCTCTGGGGGCCAAGAAGCATGACTTTGCCATCATCCGAGTAGAGGAACTCTGCCCCTTCCCGTTGGATT CTTTACAGCAAGAGATGAGCAAATACAAACATGTTAAAGATCATATTTGGAGTCAGGAGGAACCTCAGAACATGGGTCCGTGGTCGTTTG TTTCTCCAAGGTTTGAAAAGCAGCTGGCCTGCAAGCTCCGTCTGGTGGGCCGGCCCCCTTTGCCAGTACCCGCTGTAGGAATTGGCACAG TTCACTTGCACCAGCATGAAGATATCCTCGCCAAGACCTTCGCTTGATGATGACTTTTGAAGAAACACTATTTCTCTTTAAGAAAATGGC CATTAAGGCCGGGTGGGGTGGCACATGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCTGGTGGATCACCTGAGGTCAGGAGTTCGAGA CCAGCCTGGCCAACACGGTGAAACCCCGCCTCTACTAAAAATACAAAAAATAGCCGGGTGTGGTGGTGGGCACCTGTGATCCCAGCTTCC TGGGAGGCTGAGGCAAGAGAATCGCTTGAATCTGGGAGGCGGAGGTTGCAGTGAGCCAGGATCACACCATTGCTGTCCAGCCTGGGTGAC AGAGCAAGACTGCGTTTCAAAAAAAAAAAAAAAAAAACCCATTAAAAGAGGCCTCCTTCCTCCACTCTCTCAACCCCTCTGTTGGGTAAC ATGAAAAGACTGTATTCCTCTAAGATGTTGGGATTGATATACGTGATTTAATCTGCAATAGGTGGAATAACCAGGGGAACTGGTTATGAA TATGTGAATGCAACCAGCAAATTTATCCTTGAAGGTGTGATGGTAGAAATAGGAAAACAACAAAAGAAAAACAATAACAAAAAAAGAAAG TGTGATGGCTGGGTGCAGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTTAGGCGGCTGGATCACCTGAGGTCAGGAGTTCAAGA CCAGCCTGGTCAACGTGGTGAAACGCCGTTTCTACTAAAAATATGAAAATTAGTTGGGTGTGGTGGCATGCGCTTGTAGTCTCAGCTACT CCGGAGGCTGAGGCAGGAGAATTGCTTGAACCTGGAAGGCAGAGGTTGCAGTGAGCCGAAATGGCGCCACTGTACTCCAACCTGGGCGAC AGAGCAAGACTCCATCTCATAAATTAAAAGGAAAGTATGATAGTGTTATGGATTTTAGCTCTGAGTGAGCTGGAAAACTAGGTCATTATC TAGATGATTTCAGACTTGACCCTAATTGACCATATATGACCAGGAAACACTTCTGAGTTTACAGCTCCGTGGAGATGACCTCAACACTGC CTCTTGATTTGTTTGATGCATGTCACTTTCATTAATTTTCCCCCTCCTTTTTGAAAGTCCTGTGGCAGTACTAATATTTTCATTTTATGT AATCTCTGGTGCTGCTTTCCAGTCACTGTATGAAGTGTCTCCCCAACACTAGCAAATCTAGGTCCTACTAAATACAAATCTCTGGGTGGA TGATCTTCTAGTACTGTATTTTTAAATTAAGGAGTTTTAGTTATAATGAAATTGATTTGTAGTCTGTTTTGCCGTAAACTTGTTTTTCTT TAAATTGTTCTTACAGTGATATCTTACTATTTTTAACTGTCTGGGGTTTCTGATATGGGGATTTCAGCCCCTGGTTAATCAGTCTTGTCC CTACAAGTCCCTGATGCAGTATGTTTATTTGTGATGTTTAAAGAACATTTCTTGGCTGGGCGCTGCGGCTTGCGCCTGTAATCTCAGCAC TTTGGGAGGCTGAGATGGGTGGATCACCTGAGGTTGGGAGTTCGAGACCAGCCTGACAAAACATAGTGAAACCCCGTCTCTACTAAAAAT ACAAAAATTAGCTGGGCGTGGTGGTGGGTGTCTGTAATCCCAGCTATTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGAGGTGG AGGTTGCAGTGAGCTGAGATCCTGCCACTGCACTCCAGTCTGGGTGACAGAGCAAGACTCCATCTCAAAAAATAAATAAATAGAAAGAGA GAGAGAGGAAAAAAAAAGAAAAGAACACTTCTTTATTTGAGGGACTTTCCCAACACCAGGTGCTTGGGGATTTCTTAGAGATCACCAACC GACTCCCTCACTGTGAAATTAAACCAAGTACTGGAAACGTAACTAAACAGCGAACCATGTAGCTTCACCTGACTCAGTGCTGGGGGCCTC TACCATCTACTGTGCTTGTGTCATGATGCTTTTTCTCTGAAGTGGTGTGGGAAGTACCAGGGGACTGGCAGAAGCCCAGGCCCTCTCTAC TTTTACCAGCAACTGATCATGTCTTTCAGAATCCATGTACATATAGGCTGTTCTAGCCACAGTGGTAGATTTATGATTCACATCCGAAAG TGTGCCTTAGTTATCAATTTAACATTTCTCTAGTATTCATATCCCTTTTCTTACCATATACCTCAGTGTATCCTTCCTGTGTCAAGCCTT ATAAATCATGTAATTTAGTGCCACTCATGTAAATCAGTAAAATCACAAAGGTCTATTTAATGAAAACGATTTACCAATGTTGTTTTTTTT >In-frame_PPP2R2A_ENST00000315985_chr8_26151256_+_DHTKD1_ENST00000263035_chr10_12123471_+_5086nt ATATGAATCATTACTCCTTACCCAGGCAGTAATGTTCCCGAAGTTTTCTCTTCGTTCTATGTTTCATGGAGCTGGAGGAGGGAATGATAT TCAGTGGTGTTTTTCTCAGGTGAAAGGAGCAGTAGATGATGATGTAGCAGAAGTTGATCATGGCCTTGCCAGGTTGGTGACAGTATATTG TGAGCATGGTCATAAAGCTGCCAAAATCAACCCCCTCTTCACCGGACAAGCCCTGCTGGAGAATGTGCCTGAAATCCAAGCCCTGGTGCA GACACTGCAGGGACCCTTCCACACGGCAGGATTATTGAACATGGGGAAGGAAGAGGCCTCACTTGAGGAAGTGTTAGTCTATCTCAATCA AATCTACTGTGGGCAGATTTCTATTGAAACCTCCCAACTTCAGAGCCAGGATGAGAAAGACTGGTTTGCCAAGCGGTTTGAGGAACTGCA AAAGGAGACGTTTACCACAGAAGAGCGAAAACATCTGTCGAAACTAATGCTGGAATCTCAGGAGTTTGACCACTTTCTGGCCACCAAGTT CTCGACAGTGAAGCGATATGGAGGCGAAGGGGCTGAAAGCATGATGGGCTTTTTCCACGAGCTGCTGAAAATGTCGGCCTACAGCGGGAT CACTGATGTCATTATTGGGATGCCCCATAGAGGGAGGCTGAATTTATTGACAGGCCTTCTGCAGTTCCCTCCAGAGCTGATGTTCCGTAA AATGCGAGGCTTAAGTGAATTTCCAGAGAATTTCTCAGCCACTGGAGACGTCCTGTCTCACCTGACCTCCTCTGTGGACCTGTACTTTGG GGCGCACCATCCCCTCCATGTGACAATGTTGCCCAATCCCTCGCACCTGGAGGCCGTCAACCCCGTGGCCGTGGGCAAAACTCGCGGCAG GCAGCAGTCTCGCCAAGACGGCGATTACTCTCCAGACAACTCAGCCCAGCCGGGGGACAGGGTCATTTGCTTACAGGTCCATGGTGATGC TTCTTTCTGTGGTCAAGGGATTGTTCCTGAAACATTCACGCTGTCCAATCTCCCACATTTCAGAATTGGTGGGAGTGTGCATTTGATTGT TAATAACCAGCTGGGTTACACCACTCCAGCTGAAAGAGGAAGGTCTTCTTTATACTGCAGTGATATTGGGAAGCTTGTGGGCTGTGCCAT CATCCATGTCAATGGAGACAGCCCAGAGGAAGTGGTCCGTGCCACACGACTGGCTTTTGAATACCAACGCCAGTTCCGCAAGGATGTGAT TATTGATCTGTTGTGCTACAGGCAGTGGGGCCACAATGAGCTGGATGAGCCATTCTACACCAACCCCATCATGTACAAAATCATCAGAGC TCGAAAGAGCATTCCAGACACATATGCAGAGCACCTCATTGCTGGCGGACTCATGACGCAGGAGGAGGTGTCTGAAATAAAATCCTCCTA CTATGCCAAGTTGAATGATCACTTAAATAACATGGCCCACTACAGGCCCCCTGCCCTGAACCTGCAGGCCCACTGGCAGGGCCTGGCTCA GCCAGAAGCGCAAATCACCACCTGGAGTACAGGTGTGCCCCTCGACCTCCTGCGGTTTGTTGGCATGAAGTCTGTAGAGGTGCCAAGAGA GCTGCAGATGCACAGTCACCTGCTGAAGACACATGTTCAGTCCAGAATGGAGAAGATGATGGACGGAATCAAGCTAGACTGGGCCACCGC GGAAGCTCTTGCCTTGGGTTCTTTACTTGCTCAAGGTTTTAATGTTCGTCTAAGTGGCCAAGATGTTGGTCGTGGAACTTTCAGTCAGAG GCATGCAATCGTGGTTTGCCAGGAGACGGATGACACCTACATCCCCCTGAACCATATGGACCCAAATCAGAAGGGGTTTCTAGAGGTCAG CAACAGCCCACTGTCAGAAGAGGCCGTCCTGGGATTTGAATATGGGATGAGCATTGAGAGCCCAAAGTTACTGCCCCTGTGGGAGGCACA GTTTGGCGATTTCTTCAATGGTGCCCAGATCATCTTTGACACATTCATCTCTGGAGGAGAGGCCAAGTGGCTCCTACAAAGCGGCATCGT CATCCTCCTTCCACATGGCTACGATGGGGCTGGGCCAGACCACTCATCCTGTCGAATAGAGCGTTTCCTGCAGATGTGTGACAGTGCGGA AGAGGGGGTGGACGGAGACACTGTGAACATGTTTGTGGTTCACCCAACAACTCCTGCACAGTATTTCCACTTGCTTAGGAGACAGATGGT CCGGAACTTCAGAAAACCACTCATTGTTGCTTCCCCTAAGATGTTACTCAGGCTCCCGGCAGCCGTGTCAACTCTTCAAGAAATGGCACC AGGAACAACATTTAACCCGGTCATTGGTGATTCATCTGTGGATCCAAAAAAGGTTAAGACCCTCGTGTTCTGCTCCGGCAAACATTTCTA CTCCCTGGTGAAACAAAGAGAATCTCTGGGGGCCAAGAAGCATGACTTTGCCATCATCCGAGTAGAGGAACTCTGCCCCTTCCCGTTGGA TTCTTTACAGCAAGAGATGAGCAAATACAAACATGTTAAAGATCATATTTGGAGTCAGGAGGAACCTCAGAACATGGGTCCGTGGTCGTT TGTTTCTCCAAGGTTTGAAAAGCAGCTGGCCTGCAAGCTCCGTCTGGTGGGCCGGCCCCCTTTGCCAGTACCCGCTGTAGGAATTGGCAC AGTTCACTTGCACCAGCATGAAGATATCCTCGCCAAGACCTTCGCTTGATGATGACTTTTGAAGAAACACTATTTCTCTTTAAGAAAATG GCCATTAAGGCCGGGTGGGGTGGCACATGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCTGGTGGATCACCTGAGGTCAGGAGTTCGA GACCAGCCTGGCCAACACGGTGAAACCCCGCCTCTACTAAAAATACAAAAAATAGCCGGGTGTGGTGGTGGGCACCTGTGATCCCAGCTT CCTGGGAGGCTGAGGCAAGAGAATCGCTTGAATCTGGGAGGCGGAGGTTGCAGTGAGCCAGGATCACACCATTGCTGTCCAGCCTGGGTG ACAGAGCAAGACTGCGTTTCAAAAAAAAAAAAAAAAAAACCCATTAAAAGAGGCCTCCTTCCTCCACTCTCTCAACCCCTCTGTTGGGTA ACATGAAAAGACTGTATTCCTCTAAGATGTTGGGATTGATATACGTGATTTAATCTGCAATAGGTGGAATAACCAGGGGAACTGGTTATG AATATGTGAATGCAACCAGCAAATTTATCCTTGAAGGTGTGATGGTAGAAATAGGAAAACAACAAAAGAAAAACAATAACAAAAAAAGAA AGTGTGATGGCTGGGTGCAGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTTAGGCGGCTGGATCACCTGAGGTCAGGAGTTCAA GACCAGCCTGGTCAACGTGGTGAAACGCCGTTTCTACTAAAAATATGAAAATTAGTTGGGTGTGGTGGCATGCGCTTGTAGTCTCAGCTA CTCCGGAGGCTGAGGCAGGAGAATTGCTTGAACCTGGAAGGCAGAGGTTGCAGTGAGCCGAAATGGCGCCACTGTACTCCAACCTGGGCG ACAGAGCAAGACTCCATCTCATAAATTAAAAGGAAAGTATGATAGTGTTATGGATTTTAGCTCTGAGTGAGCTGGAAAACTAGGTCATTA TCTAGATGATTTCAGACTTGACCCTAATTGACCATATATGACCAGGAAACACTTCTGAGTTTACAGCTCCGTGGAGATGACCTCAACACT GCCTCTTGATTTGTTTGATGCATGTCACTTTCATTAATTTTCCCCCTCCTTTTTGAAAGTCCTGTGGCAGTACTAATATTTTCATTTTAT GTAATCTCTGGTGCTGCTTTCCAGTCACTGTATGAAGTGTCTCCCCAACACTAGCAAATCTAGGTCCTACTAAATACAAATCTCTGGGTG GATGATCTTCTAGTACTGTATTTTTAAATTAAGGAGTTTTAGTTATAATGAAATTGATTTGTAGTCTGTTTTGCCGTAAACTTGTTTTTC TTTAAATTGTTCTTACAGTGATATCTTACTATTTTTAACTGTCTGGGGTTTCTGATATGGGGATTTCAGCCCCTGGTTAATCAGTCTTGT CCCTACAAGTCCCTGATGCAGTATGTTTATTTGTGATGTTTAAAGAACATTTCTTGGCTGGGCGCTGCGGCTTGCGCCTGTAATCTCAGC ACTTTGGGAGGCTGAGATGGGTGGATCACCTGAGGTTGGGAGTTCGAGACCAGCCTGACAAAACATAGTGAAACCCCGTCTCTACTAAAA ATACAAAAATTAGCTGGGCGTGGTGGTGGGTGTCTGTAATCCCAGCTATTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGAGGT GGAGGTTGCAGTGAGCTGAGATCCTGCCACTGCACTCCAGTCTGGGTGACAGAGCAAGACTCCATCTCAAAAAATAAATAAATAGAAAGA GAGAGAGAGGAAAAAAAAAGAAAAGAACACTTCTTTATTTGAGGGACTTTCCCAACACCAGGTGCTTGGGGATTTCTTAGAGATCACCAA CCGACTCCCTCACTGTGAAATTAAACCAAGTACTGGAAACGTAACTAAACAGCGAACCATGTAGCTTCACCTGACTCAGTGCTGGGGGCC TCTACCATCTACTGTGCTTGTGTCATGATGCTTTTTCTCTGAAGTGGTGTGGGAAGTACCAGGGGACTGGCAGAAGCCCAGGCCCTCTCT ACTTTTACCAGCAACTGATCATGTCTTTCAGAATCCATGTACATATAGGCTGTTCTAGCCACAGTGGTAGATTTATGATTCACATCCGAA AGTGTGCCTTAGTTATCAATTTAACATTTCTCTAGTATTCATATCCCTTTTCTTACCATATACCTCAGTGTATCCTTCCTGTGTCAAGCC TTATAAATCATGTAATTTAGTGCCACTCATGTAAATCAGTAAAATCACAAAGGTCTATTTAATGAAAACGATTTACCAATGTTGTTTTTT |
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FusionGenePPI for PPP2R2A_DHTKD1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| PPP2R2A | FAM107A, TCEAL1, PPP2CA, PPP2R1B, EIF4EBP1, MTOR, RPS6KB1, RRN3, PPP2R1A, PPP2CB, TGFBR1, MLH1, PPP2R2D, CDCA4, SKIV2L2, CCT5, CCT8, CCT2, CCT4, CCT7, TUBA4A, CCT3, TCP1, FABP5, DSP, DSG1, CCT6A, GAPDH, HDAC5, NDRG1, ELAVL1, CUL3, PTPN14, GRK5, NOTCH1, SMURF1, GRB2, CFTR, EGFR, CDK17, CDK16, LATS2, HSPA4L, NRD1, CACNA1S, PPP3CA, THUMPD1, ABCE1, FAM122A, SERTAD4, IER2, RPS6KB2, NCAPD3, PPP2R5C, PPP2R5D, WDR4, NTRK1, AHI1, XPO1, PPME1, FOXC1, FOXC2, GC, RPS28, YARS, RBM7, RAB11FIP5, ECSIT, FBXL16, CRY2, MCM2, NOSIP, C1orf131, PTAR1, WWP2, DERL1, DUSP19, PHLPP1, PPP4C, PTPDC1, FOXD4, FAM19A3, AR, UBE2A | DHTKD1 | FAHD1, DLD, PGLYRP3, RIMKLA, NTRK1, CEP170P1, ARNTL2, DENR, MORN5, ICAM1, YBEY, GATC |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for PPP2R2A_DHTKD1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for PPP2R2A_DHTKD1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | PPP2R2A | C0013990 | Pathological accumulation of air in tissues | 1 | CTD_human |
| Hgene | PPP2R2A | C1257806 | Chromosomal Instability | 1 | CTD_human |
| Hgene | PPP2R2A | C1449861 | Micronuclei, Chromosome-Defective | 1 | CTD_human |
| Tgene | DHTKD1 | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |
| Tgene | DHTKD1 | C1859817 | 2-AMINOADIPIC 2-OXOADIPIC ACIDURIA | 1 | ORPHANET;UNIPROT |
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