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Fusion gene ID: 28155 |
FusionGeneSummary for PPFIA1_XRRA1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PPFIA1_XRRA1 | Fusion gene ID: 28155 | Hgene | Tgene | Gene symbol | PPFIA1 | XRRA1 | Gene ID | 8500 | 143570 |
| Gene name | PTPRF interacting protein alpha 1 | X-ray radiation resistance associated 1 | |
| Synonyms | LIP.1|LIP1|LIPRIN | - | |
| Cytomap | 11q13.3 | 11q13.4 | |
| Type of gene | protein-coding | protein-coding | |
| Description | liprin-alpha-1LAR-interacting protein 1LIP-1Liprin-alpha1protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | X-ray radiation resistance-associated protein 1 | |
| Modification date | 20180522 | 20180519 | |
| UniProtAcc | Q13136 | Q6P2D8 | |
| Ensembl transtripts involved in fusion gene | ENST00000253925, ENST00000389547, ENST00000530548, | ENST00000340360, ENST00000321448, ENST00000527087, ENST00000533598, | |
| Fusion gene scores | * DoF score | 36 X 13 X 14=6552 | 6 X 5 X 5=150 |
| # samples | 41 | 8 | |
| ** MAII score | log2(41/6552*10)=-3.99823954213556 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(8/150*10)=-0.906890595608519 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: PPFIA1 [Title/Abstract] AND XRRA1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | XRRA1 | GO:0010165 | response to X-ray | 12908878 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-BH-A0C3-01A | PPFIA1 | chr11 | 70208594 | + | XRRA1 | chr11 | 74648113 | - |
| TCGA | LD | ESCA | TCGA-L5-A8NE-01A | PPFIA1 | chr11 | 70118542 | + | XRRA1 | chr11 | 74559507 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000253925 | ENST00000340360 | PPFIA1 | chr11 | 70208594 | + | XRRA1 | chr11 | 74648113 | - |
| 5CDS-5UTR | ENST00000253925 | ENST00000321448 | PPFIA1 | chr11 | 70208594 | + | XRRA1 | chr11 | 74648113 | - |
| 5CDS-5UTR | ENST00000253925 | ENST00000527087 | PPFIA1 | chr11 | 70208594 | + | XRRA1 | chr11 | 74648113 | - |
| 5CDS-5UTR | ENST00000253925 | ENST00000533598 | PPFIA1 | chr11 | 70208594 | + | XRRA1 | chr11 | 74648113 | - |
| Frame-shift | ENST00000389547 | ENST00000340360 | PPFIA1 | chr11 | 70208594 | + | XRRA1 | chr11 | 74648113 | - |
| 5CDS-5UTR | ENST00000389547 | ENST00000321448 | PPFIA1 | chr11 | 70208594 | + | XRRA1 | chr11 | 74648113 | - |
| 5CDS-5UTR | ENST00000389547 | ENST00000527087 | PPFIA1 | chr11 | 70208594 | + | XRRA1 | chr11 | 74648113 | - |
| 5CDS-5UTR | ENST00000389547 | ENST00000533598 | PPFIA1 | chr11 | 70208594 | + | XRRA1 | chr11 | 74648113 | - |
| intron-3CDS | ENST00000530548 | ENST00000340360 | PPFIA1 | chr11 | 70208594 | + | XRRA1 | chr11 | 74648113 | - |
| intron-5UTR | ENST00000530548 | ENST00000321448 | PPFIA1 | chr11 | 70208594 | + | XRRA1 | chr11 | 74648113 | - |
| intron-5UTR | ENST00000530548 | ENST00000527087 | PPFIA1 | chr11 | 70208594 | + | XRRA1 | chr11 | 74648113 | - |
| intron-5UTR | ENST00000530548 | ENST00000533598 | PPFIA1 | chr11 | 70208594 | + | XRRA1 | chr11 | 74648113 | - |
| In-frame | ENST00000253925 | ENST00000340360 | PPFIA1 | chr11 | 70118542 | + | XRRA1 | chr11 | 74559507 | - |
| In-frame | ENST00000253925 | ENST00000321448 | PPFIA1 | chr11 | 70118542 | + | XRRA1 | chr11 | 74559507 | - |
| In-frame | ENST00000253925 | ENST00000527087 | PPFIA1 | chr11 | 70118542 | + | XRRA1 | chr11 | 74559507 | - |
| 5CDS-intron | ENST00000253925 | ENST00000533598 | PPFIA1 | chr11 | 70118542 | + | XRRA1 | chr11 | 74559507 | - |
| In-frame | ENST00000389547 | ENST00000340360 | PPFIA1 | chr11 | 70118542 | + | XRRA1 | chr11 | 74559507 | - |
| In-frame | ENST00000389547 | ENST00000321448 | PPFIA1 | chr11 | 70118542 | + | XRRA1 | chr11 | 74559507 | - |
| In-frame | ENST00000389547 | ENST00000527087 | PPFIA1 | chr11 | 70118542 | + | XRRA1 | chr11 | 74559507 | - |
| 5CDS-intron | ENST00000389547 | ENST00000533598 | PPFIA1 | chr11 | 70118542 | + | XRRA1 | chr11 | 74559507 | - |
| intron-3CDS | ENST00000530548 | ENST00000340360 | PPFIA1 | chr11 | 70118542 | + | XRRA1 | chr11 | 74559507 | - |
| intron-3CDS | ENST00000530548 | ENST00000321448 | PPFIA1 | chr11 | 70118542 | + | XRRA1 | chr11 | 74559507 | - |
| intron-3CDS | ENST00000530548 | ENST00000527087 | PPFIA1 | chr11 | 70118542 | + | XRRA1 | chr11 | 74559507 | - |
| intron-intron | ENST00000530548 | ENST00000533598 | PPFIA1 | chr11 | 70118542 | + | XRRA1 | chr11 | 74559507 | - |
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FusionProtFeatures for PPFIA1_XRRA1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| PPFIA1 | XRRA1 |
| May regulate the disassembly of focal adhesions. Maylocalize receptor-like tyrosine phosphatases type 2A at specificsites on the plasma membrane, possibly regulating theirinteraction with the extracellular environment and theirassociation with substrates. {ECO:0000269|PubMed:7796809}. | May be involved in the response of cells to X-rayradiation. {ECO:0000269|PubMed:12908878}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | PPFIA1 | chr11:70118542 | chr11:74559507 | ENST00000253925 | + | 2 | 28 | 17_25 | 88 | 1597 | Compositional bias | Note=Poly-Gly |
| Hgene | PPFIA1 | chr11:70118542 | chr11:74559507 | ENST00000389547 | + | 2 | 26 | 17_25 | 88 | 1186 | Compositional bias | Note=Poly-Gly |
| Tgene | >XRRA1 | chr11:70118542 | chr11:74559507 | ENST00000321448 | - | 10 | 16 | 723_745 | 177 | 518 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >XRRA1 | chr11:70118542 | chr11:74559507 | ENST00000340360 | - | 13 | 19 | 723_745 | 452 | 793 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >XRRA1 | chr11:70118542 | chr11:74559507 | ENST00000527087 | - | 10 | 15 | 723_745 | 365 | 599 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >XRRA1 | chr11:70118542 | chr11:74559507 | ENST00000321448 | - | 10 | 16 | 188_209 | 177 | 518 | Repeat | Note=LRR 4 |
| Tgene | >XRRA1 | chr11:70118542 | chr11:74559507 | ENST00000321448 | - | 10 | 16 | 229_250 | 177 | 518 | Repeat | Note=LRR 5 |
| Tgene | >XRRA1 | chr11:70118542 | chr11:74559507 | ENST00000321448 | - | 10 | 16 | 254_275 | 177 | 518 | Repeat | Note=LRR 6 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >PPFIA1 | chr11:70118542 | chr11:74559507 | ENST00000253925 | + | 2 | 28 | 1021_1050 | 88 | 1597 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >PPFIA1 | chr11:70118542 | chr11:74559507 | ENST00000253925 | + | 2 | 28 | 176_214 | 88 | 1597 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >PPFIA1 | chr11:70118542 | chr11:74559507 | ENST00000253925 | + | 2 | 28 | 249_521 | 88 | 1597 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >PPFIA1 | chr11:70118542 | chr11:74559507 | ENST00000253925 | + | 2 | 28 | 34_141 | 88 | 1597 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >PPFIA1 | chr11:70118542 | chr11:74559507 | ENST00000253925 | + | 2 | 28 | 623_669 | 88 | 1597 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >PPFIA1 | chr11:70118542 | chr11:74559507 | ENST00000253925 | + | 2 | 28 | 847_871 | 88 | 1597 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >PPFIA1 | chr11:70118542 | chr11:74559507 | ENST00000389547 | + | 2 | 26 | 1021_1050 | 88 | 1186 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >PPFIA1 | chr11:70118542 | chr11:74559507 | ENST00000389547 | + | 2 | 26 | 176_214 | 88 | 1186 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >PPFIA1 | chr11:70118542 | chr11:74559507 | ENST00000389547 | + | 2 | 26 | 249_521 | 88 | 1186 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >PPFIA1 | chr11:70118542 | chr11:74559507 | ENST00000389547 | + | 2 | 26 | 34_141 | 88 | 1186 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >PPFIA1 | chr11:70118542 | chr11:74559507 | ENST00000389547 | + | 2 | 26 | 623_669 | 88 | 1186 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >PPFIA1 | chr11:70118542 | chr11:74559507 | ENST00000389547 | + | 2 | 26 | 847_871 | 88 | 1186 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >PPFIA1 | chr11:70118542 | chr11:74559507 | ENST00000253925 | + | 2 | 28 | 1051_1120 | 88 | 1597 | Domain | SAM 3 |
| Hgene | >PPFIA1 | chr11:70118542 | chr11:74559507 | ENST00000253925 | + | 2 | 28 | 878_944 | 88 | 1597 | Domain | SAM 1 |
| Hgene | >PPFIA1 | chr11:70118542 | chr11:74559507 | ENST00000253925 | + | 2 | 28 | 963_1027 | 88 | 1597 | Domain | SAM 2 |
| Hgene | >PPFIA1 | chr11:70118542 | chr11:74559507 | ENST00000389547 | + | 2 | 26 | 1051_1120 | 88 | 1186 | Domain | SAM 3 |
| Hgene | >PPFIA1 | chr11:70118542 | chr11:74559507 | ENST00000389547 | + | 2 | 26 | 878_944 | 88 | 1186 | Domain | SAM 1 |
| Hgene | >PPFIA1 | chr11:70118542 | chr11:74559507 | ENST00000389547 | + | 2 | 26 | 963_1027 | 88 | 1186 | Domain | SAM 2 |
| Tgene | XRRA1 | chr11:70118542 | chr11:74559507 | ENST00000321448 | - | 10 | 16 | 104_125 | 177 | 518 | Repeat | Note=LRR 1 |
| Tgene | XRRA1 | chr11:70118542 | chr11:74559507 | ENST00000321448 | - | 10 | 16 | 141_155 | 177 | 518 | Repeat | Note=LRR 2 |
| Tgene | XRRA1 | chr11:70118542 | chr11:74559507 | ENST00000321448 | - | 10 | 16 | 164_184 | 177 | 518 | Repeat | Note=LRR 3 |
| Tgene | XRRA1 | chr11:70118542 | chr11:74559507 | ENST00000340360 | - | 13 | 19 | 104_125 | 452 | 793 | Repeat | Note=LRR 1 |
| Tgene | XRRA1 | chr11:70118542 | chr11:74559507 | ENST00000340360 | - | 13 | 19 | 141_155 | 452 | 793 | Repeat | Note=LRR 2 |
| Tgene | XRRA1 | chr11:70118542 | chr11:74559507 | ENST00000340360 | - | 13 | 19 | 164_184 | 452 | 793 | Repeat | Note=LRR 3 |
| Tgene | XRRA1 | chr11:70118542 | chr11:74559507 | ENST00000340360 | - | 13 | 19 | 188_209 | 452 | 793 | Repeat | Note=LRR 4 |
| Tgene | XRRA1 | chr11:70118542 | chr11:74559507 | ENST00000340360 | - | 13 | 19 | 229_250 | 452 | 793 | Repeat | Note=LRR 5 |
| Tgene | XRRA1 | chr11:70118542 | chr11:74559507 | ENST00000340360 | - | 13 | 19 | 254_275 | 452 | 793 | Repeat | Note=LRR 6 |
| Tgene | XRRA1 | chr11:70118542 | chr11:74559507 | ENST00000527087 | - | 10 | 15 | 104_125 | 365 | 599 | Repeat | Note=LRR 1 |
| Tgene | XRRA1 | chr11:70118542 | chr11:74559507 | ENST00000527087 | - | 10 | 15 | 141_155 | 365 | 599 | Repeat | Note=LRR 2 |
| Tgene | XRRA1 | chr11:70118542 | chr11:74559507 | ENST00000527087 | - | 10 | 15 | 164_184 | 365 | 599 | Repeat | Note=LRR 3 |
| Tgene | XRRA1 | chr11:70118542 | chr11:74559507 | ENST00000527087 | - | 10 | 15 | 188_209 | 365 | 599 | Repeat | Note=LRR 4 |
| Tgene | XRRA1 | chr11:70118542 | chr11:74559507 | ENST00000527087 | - | 10 | 15 | 229_250 | 365 | 599 | Repeat | Note=LRR 5 |
| Tgene | XRRA1 | chr11:70118542 | chr11:74559507 | ENST00000527087 | - | 10 | 15 | 254_275 | 365 | 599 | Repeat | Note=LRR 6 |
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FusionGeneSequence for PPFIA1_XRRA1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_PPFIA1_ENST00000253925_chr11_70118542_+_XRRA1_ENST00000340360_chr11_74559507_-_429aa MMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLMVSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQVK SEIPKVPKQPLVLHHPRMTTTKSPSKDMLEPEAELAEDLPTTKSTSVESEMPTENLEGHSPSCRTFVPLPPICSNSTVHSEETLSHLSDT TVRLSPERPSDEDSKSTESIFLTQVSELPSSVIHKDDLELKEKDQKKPPTAPREVKGTRRKLPTAFLPSKYHGYEELLTAKPDPAFIEPK GIQKNAQALQQMLKHPLLCHSSKPKLDTLQKPYVHKEKRAQRIPIPPPKKTRAQLLDDIFIRLRDPRNITEAPLGAVLHQWTERRLVNHK >In-frame_PPFIA1_ENST00000253925_chr11_70118542_+_XRRA1_ENST00000321448_chr11_74559507_-_429aa MMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLMVSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQVK SEIPKVPKQPLVLHHPRMTTTKSPSKDMLEPEAELAEDLPTTKSTSVESEMPTENLEGHSPSCRTFVPLPPICSNSTVHSEETLSHLSDT TVRLSPERPSDEDSKSTESIFLTQVSELPSSVIHKDDLELKEKDQKKPPTAPREVKGTRRKLPTAFLPSKYHGYEELLTAKPDPAFIEPK GIQKNAQALQQMLKHPLLCHSSKPKLDTLQKPYVHKEKRAQRIPIPPPKKTRAQLLDDIFIRLRDPRNITEAPLGAVLHQWTERRLVNHK >In-frame_PPFIA1_ENST00000253925_chr11_70118542_+_XRRA1_ENST00000527087_chr11_74559507_-_322aa MMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLMVSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQVK SEIPKVPKQPLVLHHPRMTTTKSPSKDMLEPEAELAEDLPTTKSTSVESEMPTENLEGHSPSCRTFVPLPPICSNSTVHSEETLSHLSDT TVRLSPERPSDEDSKSTESIFLTQVSELPSSVIHKDDLELKEKDQKKPPTAPREVKGTRRKLPTAFLPSKYHGYEELLTAKPDPAFIEPK >In-frame_PPFIA1_ENST00000389547_chr11_70118542_+_XRRA1_ENST00000340360_chr11_74559507_-_429aa MMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLMVSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQVK SEIPKVPKQPLVLHHPRMTTTKSPSKDMLEPEAELAEDLPTTKSTSVESEMPTENLEGHSPSCRTFVPLPPICSNSTVHSEETLSHLSDT TVRLSPERPSDEDSKSTESIFLTQVSELPSSVIHKDDLELKEKDQKKPPTAPREVKGTRRKLPTAFLPSKYHGYEELLTAKPDPAFIEPK GIQKNAQALQQMLKHPLLCHSSKPKLDTLQKPYVHKEKRAQRIPIPPPKKTRAQLLDDIFIRLRDPRNITEAPLGAVLHQWTERRLVNHK >In-frame_PPFIA1_ENST00000389547_chr11_70118542_+_XRRA1_ENST00000321448_chr11_74559507_-_429aa MMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLMVSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQVK SEIPKVPKQPLVLHHPRMTTTKSPSKDMLEPEAELAEDLPTTKSTSVESEMPTENLEGHSPSCRTFVPLPPICSNSTVHSEETLSHLSDT TVRLSPERPSDEDSKSTESIFLTQVSELPSSVIHKDDLELKEKDQKKPPTAPREVKGTRRKLPTAFLPSKYHGYEELLTAKPDPAFIEPK GIQKNAQALQQMLKHPLLCHSSKPKLDTLQKPYVHKEKRAQRIPIPPPKKTRAQLLDDIFIRLRDPRNITEAPLGAVLHQWTERRLVNHK >In-frame_PPFIA1_ENST00000389547_chr11_70118542_+_XRRA1_ENST00000527087_chr11_74559507_-_322aa MMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLMVSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQVK SEIPKVPKQPLVLHHPRMTTTKSPSKDMLEPEAELAEDLPTTKSTSVESEMPTENLEGHSPSCRTFVPLPPICSNSTVHSEETLSHLSDT TVRLSPERPSDEDSKSTESIFLTQVSELPSSVIHKDDLELKEKDQKKPPTAPREVKGTRRKLPTAFLPSKYHGYEELLTAKPDPAFIEPK |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_PPFIA1_ENST00000253925_chr11_70118542_+_XRRA1_ENST00000340360_chr11_74559507_-_1287nt ATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAGGTGGAGGCCATGGTTCCGGCTCCCCTTCACAGCCA GATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACCGCCTTCTTGATACACTGAGAGAGACTCAAGAAACG CTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGCAGAGACAGCTCAACACGGCACTTCCACAGGTGAAA AGCGAAATCCCAAAGGTGCCGAAGCAGCCTCTGGTGCTCCATCACCCGCGCATGACGACAACCAAGTCTCCCTCAAAGGATATGCTAGAG CCAGAGGCAGAGCTGGCTGAAGATCTGCCCACTACCAAAAGCACTTCTGTGGAGTCAGAGATGCCCACTGAGAACCTGGAAGGCCATTCC CCGTCTTGCCGGACCTTCGTGCCACTGCCTCCCATCTGCTCCAACTCCACTGTGCATAGTGAAGAGACCCTGTCCCACCTGAGTGACACA ACTGTCCGCCTCAGCCCAGAGCGCCCATCAGATGAGGACTCCAAGAGCACAGAGTCCATCTTCCTGACCCAGGTGAGTGAACTGCCTTCC TCCGTCATCCATAAGGATGATTTAGAGTTAAAGGAGAAAGACCAAAAGAAACCACCAACGGCACCCAGAGAGGTGAAAGGGACTCGGAGG AAACTCCCAACTGCCTTCCTTCCCAGCAAGTACCACGGCTATGAAGAACTGCTGACAGCCAAGCCTGATCCAGCCTTCATTGAGCCAAAG GGAATCCAGAAGAATGCACAAGCCCTGCAACAAATGCTGAAGCACCCACTCCTGTGCCACTCCTCCAAGCCCAAGCTGGACACTCTTCAG AAACCCTATGTTCACAAAGAGAAACGGGCCCAGAGAATCCCGATTCCACCCCCAAAGAAGACTAGAGCCCAACTTCTGGATGACATCTTC ATTCGCTTGCGGGATCCCCGGAACATTACAGAGGCTCCACTAGGTGCTGTCCTGCACCAGTGGACAGAACGGCGGCTGGTGAACCACAAG CAGTACCTGGAGGCCAAGAGGCTGTTGAAGGAGTTCCAGGCACGTTACCGGCAGCTGGTGAGTGGCTCTCTGCGCACAGTGTTCGGGACT ACCCCGCTCCCCATGGCCTGCCCAGCGCTGAGTGAGAGCCAGCCCAAGTTCGGCCACTTCCTCGAGTTCATGGATGAGTTCTGCCAGGAG >In-frame_PPFIA1_ENST00000253925_chr11_70118542_+_XRRA1_ENST00000321448_chr11_74559507_-_1287nt ATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAGGTGGAGGCCATGGTTCCGGCTCCCCTTCACAGCCA GATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACCGCCTTCTTGATACACTGAGAGAGACTCAAGAAACG CTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGCAGAGACAGCTCAACACGGCACTTCCACAGGTGAAA AGCGAAATCCCAAAGGTGCCGAAGCAGCCTCTGGTGCTCCATCACCCGCGCATGACGACAACCAAGTCTCCCTCAAAGGATATGCTAGAG CCAGAGGCAGAGCTGGCTGAAGATCTGCCCACTACCAAAAGCACTTCTGTGGAGTCAGAGATGCCCACTGAGAACCTGGAAGGCCATTCC CCGTCTTGCCGGACCTTCGTGCCACTGCCTCCCATCTGCTCCAACTCCACTGTGCATAGTGAAGAGACCCTGTCCCACCTGAGTGACACA ACTGTCCGCCTCAGCCCAGAGCGCCCATCAGATGAGGACTCCAAGAGCACAGAGTCCATCTTCCTGACCCAGGTGAGTGAACTGCCTTCC TCCGTCATCCATAAGGATGATTTAGAGTTAAAGGAGAAAGACCAAAAGAAACCACCAACGGCACCCAGAGAGGTGAAAGGGACTCGGAGG AAACTCCCAACTGCCTTCCTTCCCAGCAAGTACCACGGCTATGAAGAACTGCTGACAGCCAAGCCTGATCCAGCCTTCATTGAGCCAAAG GGAATCCAGAAGAATGCACAAGCCCTGCAACAAATGCTGAAGCACCCACTCCTGTGCCACTCCTCCAAGCCCAAGCTGGACACTCTTCAG AAACCCTATGTTCACAAAGAGAAACGGGCCCAGAGAATCCCGATTCCACCCCCAAAGAAGACTAGAGCCCAACTTCTGGATGACATCTTC ATTCGCTTGCGGGATCCCCGGAACATTACAGAGGCTCCACTAGGTGCTGTCCTGCACCAGTGGACAGAACGGCGGCTGGTGAACCACAAG CAGTACCTGGAGGCCAAGAGGCTGTTGAAGGAGTTCCAGGCACGTTACCGGCAGCTGGTGAGTGGCTCTCTGCGCACAGTGTTCGGGACT ACCCCGCTCCCCATGGCCTGCCCAGCGCTGAGTGAGAGCCAGCCCAAGTTCGGCCACTTCCTCGAGTTCATGGATGAGTTCTGCCAGGAG >In-frame_PPFIA1_ENST00000253925_chr11_70118542_+_XRRA1_ENST00000527087_chr11_74559507_-_966nt ATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAGGTGGAGGCCATGGTTCCGGCTCCCCTTCACAGCCA GATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACCGCCTTCTTGATACACTGAGAGAGACTCAAGAAACG CTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGCAGAGACAGCTCAACACGGCACTTCCACAGGTGAAA AGCGAAATCCCAAAGGTGCCGAAGCAGCCTCTGGTGCTCCATCACCCGCGCATGACGACAACCAAGTCTCCCTCAAAGGATATGCTAGAG CCAGAGGCAGAGCTGGCTGAAGATCTGCCCACTACCAAAAGCACTTCTGTGGAGTCAGAGATGCCCACTGAGAACCTGGAAGGCCATTCC CCGTCTTGCCGGACCTTCGTGCCACTGCCTCCCATCTGCTCCAACTCCACTGTGCATAGTGAAGAGACCCTGTCCCACCTGAGTGACACA ACTGTCCGCCTCAGCCCAGAGCGCCCATCAGATGAGGACTCCAAGAGCACAGAGTCCATCTTCCTGACCCAGGTGAGTGAACTGCCTTCC TCCGTCATCCATAAGGATGATTTAGAGTTAAAGGAGAAAGACCAAAAGAAACCACCAACGGCACCCAGAGAGGTGAAAGGGACTCGGAGG AAACTCCCAACTGCCTTCCTTCCCAGCAAGTACCACGGCTATGAAGAACTGCTGACAGCCAAGCCTGATCCAGCCTTCATTGAGCCAAAG GGAATCCAGAAGAATGCACAAGCCCTGCAACAAATGCTGAAGCACCCACTCCTGTGCCACTCCTCCAAGCCCAAGCTGGACACTCTTCAG >In-frame_PPFIA1_ENST00000389547_chr11_70118542_+_XRRA1_ENST00000340360_chr11_74559507_-_1287nt ATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAGGTGGAGGCCATGGTTCCGGCTCCCCTTCACAGCCA GATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACCGCCTTCTTGATACACTGAGAGAGACTCAAGAAACG CTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGCAGAGACAGCTCAACACGGCACTTCCACAGGTGAAA AGCGAAATCCCAAAGGTGCCGAAGCAGCCTCTGGTGCTCCATCACCCGCGCATGACGACAACCAAGTCTCCCTCAAAGGATATGCTAGAG CCAGAGGCAGAGCTGGCTGAAGATCTGCCCACTACCAAAAGCACTTCTGTGGAGTCAGAGATGCCCACTGAGAACCTGGAAGGCCATTCC CCGTCTTGCCGGACCTTCGTGCCACTGCCTCCCATCTGCTCCAACTCCACTGTGCATAGTGAAGAGACCCTGTCCCACCTGAGTGACACA ACTGTCCGCCTCAGCCCAGAGCGCCCATCAGATGAGGACTCCAAGAGCACAGAGTCCATCTTCCTGACCCAGGTGAGTGAACTGCCTTCC TCCGTCATCCATAAGGATGATTTAGAGTTAAAGGAGAAAGACCAAAAGAAACCACCAACGGCACCCAGAGAGGTGAAAGGGACTCGGAGG AAACTCCCAACTGCCTTCCTTCCCAGCAAGTACCACGGCTATGAAGAACTGCTGACAGCCAAGCCTGATCCAGCCTTCATTGAGCCAAAG GGAATCCAGAAGAATGCACAAGCCCTGCAACAAATGCTGAAGCACCCACTCCTGTGCCACTCCTCCAAGCCCAAGCTGGACACTCTTCAG AAACCCTATGTTCACAAAGAGAAACGGGCCCAGAGAATCCCGATTCCACCCCCAAAGAAGACTAGAGCCCAACTTCTGGATGACATCTTC ATTCGCTTGCGGGATCCCCGGAACATTACAGAGGCTCCACTAGGTGCTGTCCTGCACCAGTGGACAGAACGGCGGCTGGTGAACCACAAG CAGTACCTGGAGGCCAAGAGGCTGTTGAAGGAGTTCCAGGCACGTTACCGGCAGCTGGTGAGTGGCTCTCTGCGCACAGTGTTCGGGACT ACCCCGCTCCCCATGGCCTGCCCAGCGCTGAGTGAGAGCCAGCCCAAGTTCGGCCACTTCCTCGAGTTCATGGATGAGTTCTGCCAGGAG >In-frame_PPFIA1_ENST00000389547_chr11_70118542_+_XRRA1_ENST00000321448_chr11_74559507_-_1287nt ATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAGGTGGAGGCCATGGTTCCGGCTCCCCTTCACAGCCA GATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACCGCCTTCTTGATACACTGAGAGAGACTCAAGAAACG CTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGCAGAGACAGCTCAACACGGCACTTCCACAGGTGAAA AGCGAAATCCCAAAGGTGCCGAAGCAGCCTCTGGTGCTCCATCACCCGCGCATGACGACAACCAAGTCTCCCTCAAAGGATATGCTAGAG CCAGAGGCAGAGCTGGCTGAAGATCTGCCCACTACCAAAAGCACTTCTGTGGAGTCAGAGATGCCCACTGAGAACCTGGAAGGCCATTCC CCGTCTTGCCGGACCTTCGTGCCACTGCCTCCCATCTGCTCCAACTCCACTGTGCATAGTGAAGAGACCCTGTCCCACCTGAGTGACACA ACTGTCCGCCTCAGCCCAGAGCGCCCATCAGATGAGGACTCCAAGAGCACAGAGTCCATCTTCCTGACCCAGGTGAGTGAACTGCCTTCC TCCGTCATCCATAAGGATGATTTAGAGTTAAAGGAGAAAGACCAAAAGAAACCACCAACGGCACCCAGAGAGGTGAAAGGGACTCGGAGG AAACTCCCAACTGCCTTCCTTCCCAGCAAGTACCACGGCTATGAAGAACTGCTGACAGCCAAGCCTGATCCAGCCTTCATTGAGCCAAAG GGAATCCAGAAGAATGCACAAGCCCTGCAACAAATGCTGAAGCACCCACTCCTGTGCCACTCCTCCAAGCCCAAGCTGGACACTCTTCAG AAACCCTATGTTCACAAAGAGAAACGGGCCCAGAGAATCCCGATTCCACCCCCAAAGAAGACTAGAGCCCAACTTCTGGATGACATCTTC ATTCGCTTGCGGGATCCCCGGAACATTACAGAGGCTCCACTAGGTGCTGTCCTGCACCAGTGGACAGAACGGCGGCTGGTGAACCACAAG CAGTACCTGGAGGCCAAGAGGCTGTTGAAGGAGTTCCAGGCACGTTACCGGCAGCTGGTGAGTGGCTCTCTGCGCACAGTGTTCGGGACT ACCCCGCTCCCCATGGCCTGCCCAGCGCTGAGTGAGAGCCAGCCCAAGTTCGGCCACTTCCTCGAGTTCATGGATGAGTTCTGCCAGGAG >In-frame_PPFIA1_ENST00000389547_chr11_70118542_+_XRRA1_ENST00000527087_chr11_74559507_-_966nt ATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAGGTGGAGGCCATGGTTCCGGCTCCCCTTCACAGCCA GATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACCGCCTTCTTGATACACTGAGAGAGACTCAAGAAACG CTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGCAGAGACAGCTCAACACGGCACTTCCACAGGTGAAA AGCGAAATCCCAAAGGTGCCGAAGCAGCCTCTGGTGCTCCATCACCCGCGCATGACGACAACCAAGTCTCCCTCAAAGGATATGCTAGAG CCAGAGGCAGAGCTGGCTGAAGATCTGCCCACTACCAAAAGCACTTCTGTGGAGTCAGAGATGCCCACTGAGAACCTGGAAGGCCATTCC CCGTCTTGCCGGACCTTCGTGCCACTGCCTCCCATCTGCTCCAACTCCACTGTGCATAGTGAAGAGACCCTGTCCCACCTGAGTGACACA ACTGTCCGCCTCAGCCCAGAGCGCCCATCAGATGAGGACTCCAAGAGCACAGAGTCCATCTTCCTGACCCAGGTGAGTGAACTGCCTTCC TCCGTCATCCATAAGGATGATTTAGAGTTAAAGGAGAAAGACCAAAAGAAACCACCAACGGCACCCAGAGAGGTGAAAGGGACTCGGAGG AAACTCCCAACTGCCTTCCTTCCCAGCAAGTACCACGGCTATGAAGAACTGCTGACAGCCAAGCCTGATCCAGCCTTCATTGAGCCAAAG GGAATCCAGAAGAATGCACAAGCCCTGCAACAAATGCTGAAGCACCCACTCCTGTGCCACTCCTCCAAGCCCAAGCTGGACACTCTTCAG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_PPFIA1_ENST00000253925_chr11_70118542_+_XRRA1_ENST00000340360_chr11_74559507_-_4472nt GCCGCGCAGCCGGGCCCGCTCCTCCTCCGCTCCGCCAGTGTCCGGCCGCGGGCCGGCCTTAGTGACTGGGGCGGCGGGCCCCGGGGCCGC GGCGTGGGGCGGGCAGGCGGACGCCGGCCGCGGGCTGCTTTCGTCGGCTCCCAAGCTCTCCCGGAGCGAGCAGCCGCCCGCGAGCCGCCG CGGAGCCTCCTCGCCCGCTCCCGCCGGCGAGCAAGATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAG GTGGAGGCCATGGTTCCGGCTCCCCTTCACAGCCAGATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACC GCCTTCTTGATACACTGAGAGAGACTCAAGAAACGCTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGC AGAGACAGCTCAACACGGCACTTCCACAGGTGAAAAGCGAAATCCCAAAGGTGCCGAAGCAGCCTCTGGTGCTCCATCACCCGCGCATGA CGACAACCAAGTCTCCCTCAAAGGATATGCTAGAGCCAGAGGCAGAGCTGGCTGAAGATCTGCCCACTACCAAAAGCACTTCTGTGGAGT CAGAGATGCCCACTGAGAACCTGGAAGGCCATTCCCCGTCTTGCCGGACCTTCGTGCCACTGCCTCCCATCTGCTCCAACTCCACTGTGC ATAGTGAAGAGACCCTGTCCCACCTGAGTGACACAACTGTCCGCCTCAGCCCAGAGCGCCCATCAGATGAGGACTCCAAGAGCACAGAGT CCATCTTCCTGACCCAGGTGAGTGAACTGCCTTCCTCCGTCATCCATAAGGATGATTTAGAGTTAAAGGAGAAAGACCAAAAGAAACCAC CAACGGCACCCAGAGAGGTGAAAGGGACTCGGAGGAAACTCCCAACTGCCTTCCTTCCCAGCAAGTACCACGGCTATGAAGAACTGCTGA CAGCCAAGCCTGATCCAGCCTTCATTGAGCCAAAGGGAATCCAGAAGAATGCACAAGCCCTGCAACAAATGCTGAAGCACCCACTCCTGT GCCACTCCTCCAAGCCCAAGCTGGACACTCTTCAGAAACCCTATGTTCACAAAGAGAAACGGGCCCAGAGAATCCCGATTCCACCCCCAA AGAAGACTAGAGCCCAACTTCTGGATGACATCTTCATTCGCTTGCGGGATCCCCGGAACATTACAGAGGCTCCACTAGGTGCTGTCCTGC ACCAGTGGACAGAACGGCGGCTGGTGAACCACAAGCAGTACCTGGAGGCCAAGAGGCTGTTGAAGGAGTTCCAGGCACGTTACCGGCAGC TGGTGAGTGGCTCTCTGCGCACAGTGTTCGGGACTACCCCGCTCCCCATGGCCTGCCCAGCGCTGAGTGAGAGCCAGCCCAAGTTCGGCC ACTTCCTCGAGTTCATGGATGAGTTCTGCCAGGAGCCCACAGCCAGTGACTCACAAGGCTAGAGCTGTGCATGGGGGCTGTGTGCACCAC CCGGCCTGTGCCCCAGCTCTCCCCGAGGGCTCTGTGCCCTGGACCGCACCTCAAGGTTGACCAGCCGGCCACAGGCCTCAGAGCTCAGCT GGGCCCCACTTGCTGGCCACAAGGTGGCATCCCCTTGTCAGGATCTCCCCTCCTTGGCCCAGGCATGACCTGGTGCCTGGCCCAGCGGCA ATAAAGAGTGGGTGCACAGGGCAATAGACTGGGTGCCACATGCATTCTTTCTTGGAACCCAGGCCACAGCAGCATTGTCACACTTCCCTC TAAAAATGGTTTTCCAGTTCAGATGCAACAGGGATACATTTGTTCTCTGTTGTATGAGAAACTGACACCAAGGGGATCTTAACAAATTCC TGAACAATGGCTCCAAAAAAGGGTATTTTTAAAAACCAGATCTTGTGAGTACAGCCCTAATGTGCAGGGACAGTGTCATCCTGTATATTC GTTCTTTACTCAGACTCTTTCTTGGTTCCTTCATTAGGAGCATGAATGGTTGAATGTGAACATGACAGTAAATTGGAGCAAACTGTAAAC TGGACATAACTTATGCCAAAAGACGTAGTTGTACACCATGGAAACCCCATCCCTGCTCCTAATCTCTACTGCCATTCTGAATGCCAAAGC AAGACATCCAACATGGGGCATCTCCCAGAGCACATACAGCACCAAAAATCCACACACAGCCTAAGCTTAACCCATGTTTTTGTCTGAGAT TGTTCACCAGAGACAAGACTCTGACTATAAACAGAACATCCACTTTCATGAGTTTCCTTTACTGTATTCTCAACTTGGGCCTTGCTTCAA GCAGGCAAACATACATTGAAGAATGCACTTTGGTACTGTTTAAATAACAACACATCAGCCCACTTGATTCCATGCCATGTCCTTGCTGAC AGAAACATCCCCAACAGGGCATGCCCTGGTCCAAGTCCTCTGTCTTTGTCAAAATGCTCTTCTGATGAGTTGGAGAGGAGGCAGCCAGCA GTGGCAGTCCACAAGGATCCAGGTACCTTCTCCAATCCTAAAGCAGACAGCAGGTTGAATAAAACCAATACACAACCTATTTTCTAGGCA GGAGGGGAAAAGGCCCTTAGGACAATAATATTTGTACAAAGAGTTGAGAGTAAACAAACAGTGTATCAGGTTCAAAAAAAAAAAAACTAT TCGTTGGCATTTAAATTTTTTTCCCTTGCATAGTATCTATTCTCTCACTAGGACTTTTAAGTGCTCTGCTGGAGGCTCAGCGTTGGTAAT ACCATGTTTGATGCAAACTTGAACCCAATGCTCTCATTGGTGGCACAGCTTTGGAGGGTGGTGGCCCCAAGAAGGGGCAATCTGCCTGCT GCTATATTAATCTGGAACCAGGGCCAACAGCTACTCTTGAACTATGGTATTTGAAGAGCGAGTTCATTGCCTGTTTTACCTTAAATGACA GGAAAGGAAGATGAACAAACCTTGCTTTGCCTTGGCTTCAAACTAGTTCTTGATTTAAGACACCAGAAAGGGAGAGAGGGAGTCTGCTTA GAGTTTGAGGTTGCCTCTCACAAGATGACAGTTAAAAGTTGCCACCTTACTTAAAAGGCATTAAGGAGGCATTTACTCACAAAGGAGAGA GAGTAAATTTTTTTCTTAAGAGGAAAAAAATACTGATAATACATAGAACAATCTGCACATCCAGTCTTGGCACTTTTTCCAATTTGACTG ATCTCTAAACTGGTGACCCTTGCATATATCTTAGTCTCTTTTCTACAATCTTCTTCAGAAAGCTACAGCAGCTAACAATCATGTATAAAG ATGCATTTCCTAGATCATCTTCAGAAGAAAATCTCTTCAGCACTTTCCCTAGAATCTGTCTCCTGACCACCCCGCCCCAGACCTGCTTTC TCTTTTGAGAATTCATAACCAGGTATGTTTAGATACCAGTTCAAAAGACCACTCTATGGGTTGATGAGGAAAAGGCTGCCTGAGGACAAT TTAAGACCATAATGAGTTTCCAATTTTTAAAGAAAATTTGGCTAGCTGGCTTTTAATTCTTAATTAAAATCATTAAATTTAATTAAAATT ATTCCAATCAAAATATATCACTTTCCAAGATTCCACATTCATATTACTTACTTATACTATGGAGACTTTCTCTACCTGAGCATGTATTCA GGGGCTATAGGTACATTTAACTCTAACTAACTGAAAAAAATCAGGAAGAAAAAACTATTAAAATAAAATAACCTCCTAAATCATTTGGGG GTATCCCCATCATTGGTGCGTGTGTCTGCGTGTGTCAAACTTTAATGATTATTTATTCAGACCCTGGAAAACCACACTATAAAATAGGGC ACTGGATCACAAGTTCGTTTGGTTAAAAAAAAAAAAAAAAAAAAGTGGGGGCGGGGGGCAGAGAAGAAGTTTAACTTGGATGATTTCCAT GCCCATTCCAGCTGTAACATTCTATGACTGTGACCCAGCCTTTGTTCTCTTTTCTCACTCTCCTACTAGACATTTCAATGAAAAGTTAGG CAGGAAAAAGGAAAGGAATCCCAAGTTGCTGCCAGCTCTGATGAGAGATCAGGTTGGGGGAGAGATTAGGTGGTTACTGAATTGAGGTGT GGGCCTCCCCTGACCATGTCAGTGATCCACAACCCACCTCACTTCTTGGGGCTTAAGCTAAAAGCAGCTTCTGAAGAGATGTTAATGTCC TGTAATCACTAGAGGAGAAAATTCATTCTCCTTCCATAACATTACTTAGTAAAGGAAAAGCGGTGGTGCAATCAAATTCACAAATACCAA TGGGGTCTCTAAAATGTAGAATGCAGCTTGCTGGGTGCTGGTCAGTTTTCTAAATGGGACCAGAAATGGCTTTCCTAAGACCATAAATGA >In-frame_PPFIA1_ENST00000253925_chr11_70118542_+_XRRA1_ENST00000321448_chr11_74559507_-_3792nt GCCGCGCAGCCGGGCCCGCTCCTCCTCCGCTCCGCCAGTGTCCGGCCGCGGGCCGGCCTTAGTGACTGGGGCGGCGGGCCCCGGGGCCGC GGCGTGGGGCGGGCAGGCGGACGCCGGCCGCGGGCTGCTTTCGTCGGCTCCCAAGCTCTCCCGGAGCGAGCAGCCGCCCGCGAGCCGCCG CGGAGCCTCCTCGCCCGCTCCCGCCGGCGAGCAAGATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAG GTGGAGGCCATGGTTCCGGCTCCCCTTCACAGCCAGATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACC GCCTTCTTGATACACTGAGAGAGACTCAAGAAACGCTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGC AGAGACAGCTCAACACGGCACTTCCACAGGTGAAAAGCGAAATCCCAAAGGTGCCGAAGCAGCCTCTGGTGCTCCATCACCCGCGCATGA CGACAACCAAGTCTCCCTCAAAGGATATGCTAGAGCCAGAGGCAGAGCTGGCTGAAGATCTGCCCACTACCAAAAGCACTTCTGTGGAGT CAGAGATGCCCACTGAGAACCTGGAAGGCCATTCCCCGTCTTGCCGGACCTTCGTGCCACTGCCTCCCATCTGCTCCAACTCCACTGTGC ATAGTGAAGAGACCCTGTCCCACCTGAGTGACACAACTGTCCGCCTCAGCCCAGAGCGCCCATCAGATGAGGACTCCAAGAGCACAGAGT CCATCTTCCTGACCCAGGTGAGTGAACTGCCTTCCTCCGTCATCCATAAGGATGATTTAGAGTTAAAGGAGAAAGACCAAAAGAAACCAC CAACGGCACCCAGAGAGGTGAAAGGGACTCGGAGGAAACTCCCAACTGCCTTCCTTCCCAGCAAGTACCACGGCTATGAAGAACTGCTGA CAGCCAAGCCTGATCCAGCCTTCATTGAGCCAAAGGGAATCCAGAAGAATGCACAAGCCCTGCAACAAATGCTGAAGCACCCACTCCTGT GCCACTCCTCCAAGCCCAAGCTGGACACTCTTCAGAAACCCTATGTTCACAAAGAGAAACGGGCCCAGAGAATCCCGATTCCACCCCCAA AGAAGACTAGAGCCCAACTTCTGGATGACATCTTCATTCGCTTGCGGGATCCCCGGAACATTACAGAGGCTCCACTAGGTGCTGTCCTGC ACCAGTGGACAGAACGGCGGCTGGTGAACCACAAGCAGTACCTGGAGGCCAAGAGGCTGTTGAAGGAGTTCCAGGCACGTTACCGGCAGC TGGTGAGTGGCTCTCTGCGCACAGTGTTCGGGACTACCCCGCTCCCCATGGCCTGCCCAGCGCTGAGTGAGAGCCAGCCCAAGTTCGGCC ACTTCCTCGAGTTCATGGATGAGTTCTGCCAGGAGCCCACAGCCAGTGACTCACAAGGCTAGAGCTGTGCATGGGGGCTGTGTGCACCAC CCGGCCTGTGCCCCAGCTCTCCCCGAGGGCTCTGTGCCCTGGACCGCACCTCAAGGTTGACCAGCCGGCCACAGGCCTCAGAGCTCAGCT GGGCCCCACTTGCTGGCCACAAGGTGGCATCCCCTTGTCAGGATCTCCCCTCCTTGGCCCAGGCATGACCTGGTGCCTGGCCCAGCGGCA ATAAAGAGTGGGTGCACAGGGCAATAGACTGGGTGCCACATGCATTCTTTCTTGGAACCCAGGCCACAGCAGCATTGTCACACTTCCCTC TAAAAATGGTTTTCCAGTTCAGATGCAACAGGGATACATTTGTTCTCTGTTGTATGAGAAACTGACACCAAGGGGATCTTAACAAATTCC TGAACAATGGCTCCAAAAAAGGGTATTTTTAAAAACCAGATCTTGTGAGTACAGCCCTAATGTGCAGGGACAGTGTCATCCTGTATATTC GTTCTTTACTCAGACTCTTTCTTGGTTCCTTCATTAGGAGCATGAATGGTTGAATGTGAACATGACAGTAAATTGGAGCAAACTGTAAAC TGGACATAACTTATGCCAAAAGACGTAGTTGTACACCATGGAAACCCCATCCCTGCTCCTAATCTCTACTGCCATTCTGAATGCCAAAGC AAGACATCCAACATGGGGCATCTCCCAGAGCACATACAGCACCAAAAATCCACACACAGCCTAAGCTTAACCCATGTTTTTGTCTGAGAT TGTTCACCAGAGACAAGACTCTGACTATAAACAGAACATCCACTTTCATGAGTTTCCTTTACTGTATTCTCAACTTGGGCCTTGCTTCAA GCAGGCAAACATACATTGAAGAATGCACTTTGGTACTGTTTAAATAACAACACATCAGCCCACTTGATTCCATGCCATGTCCTTGCTGAC AGAAACATCCCCAACAGGGCATGCCCTGGTCCAAGTCCTCTGTCTTTGTCAAAATGCTCTTCTGATGAGTTGGAGAGGAGGCAGCCAGCA GTGGCAGTCCACAAGGATCCAGGTACCTTCTCCAATCCTAAAGCAGACAGCAGGTTGAATAAAACCAATACACAACCTATTTTCTAGGCA GGAGGGGAAAAGGCCCTTAGGACAATAATATTTGTACAAAGAGTTGAGAGTAAACAAACAGTGTATCAGGTTCAAAAAAAAAAAAACTAT TCGTTGGCATTTAAATTTTTTTCCCTTGCATAGTATCTATTCTCTCACTAGGACTTTTAAGTGCTCTGCTGGAGGCTCAGCGTTGGTAAT ACCATGTTTGATGCAAACTTGAACCCAATGCTCTCATTGGTGGCACAGCTTTGGAGGGTGGTGGCCCCAAGAAGGGGCAATCTGCCTGCT GCTATATTAATCTGGAACCAGGGCCAACAGCTACTCTTGAACTATGGTATTTGAAGAGCGAGTTCATTGCCTGTTTTACCTTAAATGACA GGAAAGGAAGATGAACAAACCTTGCTTTGCCTTGGCTTCAAACTAGTTCTTGATTTAAGACACCAGAAAGGGAGAGAGGGAGTCTGCTTA GAGTTTGAGGTTGCCTCTCACAAGATGACAGTTAAAAGTTGCCACCTTACTTAAAAGGCATTAAGGAGGCATTTACTCACAAAGGAGAGA GAGTAAATTTTTTTCTTAAGAGGAAAAAAATACTGATAATACATAGAACAATCTGCACATCCAGTCTTGGCACTTTTTCCAATTTGACTG ATCTCTAAACTGGTGACCCTTGCATATATCTTAGTCTCTTTTCTACAATCTTCTTCAGAAAGCTACAGCAGCTAACAATCATGTATAAAG ATGCATTTCCTAGATCATCTTCAGAAGAAAATCTCTTCAGCACTTTCCCTAGAATCTGTCTCCTGACCACCCCGCCCCAGACCTGCTTTC TCTTTTGAGAATTCATAACCAGGTATGTTTAGATACCAGTTCAAAAGACCACTCTATGGGTTGATGAGGAAAAGGCTGCCTGAGGACAAT TTAAGACCATAATGAGTTTCCAATTTTTAAAGAAAATTTGGCTAGCTGGCTTTTAATTCTTAATTAAAATCATTAAATTTAATTAAAATT ATTCCAATCAAAATATATCACTTTCCAAGATTCCACATTCATATTACTTACTTATACTATGGAGACTTTCTCTACCTGAGCATGTATTCA GGGGCTATAGGTACATTTAACTCTAACTAACTGAAAAAAATCAGGAAGAAAAAACTATTAAAATAAAATAACCTCCTAAATCATTTGGGG >In-frame_PPFIA1_ENST00000253925_chr11_70118542_+_XRRA1_ENST00000527087_chr11_74559507_-_1628nt GCCGCGCAGCCGGGCCCGCTCCTCCTCCGCTCCGCCAGTGTCCGGCCGCGGGCCGGCCTTAGTGACTGGGGCGGCGGGCCCCGGGGCCGC GGCGTGGGGCGGGCAGGCGGACGCCGGCCGCGGGCTGCTTTCGTCGGCTCCCAAGCTCTCCCGGAGCGAGCAGCCGCCCGCGAGCCGCCG CGGAGCCTCCTCGCCCGCTCCCGCCGGCGAGCAAGATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAG GTGGAGGCCATGGTTCCGGCTCCCCTTCACAGCCAGATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACC GCCTTCTTGATACACTGAGAGAGACTCAAGAAACGCTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGC AGAGACAGCTCAACACGGCACTTCCACAGGTGAAAAGCGAAATCCCAAAGGTGCCGAAGCAGCCTCTGGTGCTCCATCACCCGCGCATGA CGACAACCAAGTCTCCCTCAAAGGATATGCTAGAGCCAGAGGCAGAGCTGGCTGAAGATCTGCCCACTACCAAAAGCACTTCTGTGGAGT CAGAGATGCCCACTGAGAACCTGGAAGGCCATTCCCCGTCTTGCCGGACCTTCGTGCCACTGCCTCCCATCTGCTCCAACTCCACTGTGC ATAGTGAAGAGACCCTGTCCCACCTGAGTGACACAACTGTCCGCCTCAGCCCAGAGCGCCCATCAGATGAGGACTCCAAGAGCACAGAGT CCATCTTCCTGACCCAGGTGAGTGAACTGCCTTCCTCCGTCATCCATAAGGATGATTTAGAGTTAAAGGAGAAAGACCAAAAGAAACCAC CAACGGCACCCAGAGAGGTGAAAGGGACTCGGAGGAAACTCCCAACTGCCTTCCTTCCCAGCAAGTACCACGGCTATGAAGAACTGCTGA CAGCCAAGCCTGATCCAGCCTTCATTGAGCCAAAGGGAATCCAGAAGAATGCACAAGCCCTGCAACAAATGCTGAAGCACCCACTCCTGT GCCACTCCTCCAAGCCCAAGCTGGACACTCTTCAGAAACCCTATGTTCACAAAGAGAAACGGGTGCTGTCCTGCACCAGTGGACAGAACG GCGGCTGGTGAACCACAAGCAGTACCTGGAGGCCAAGAGGCTGTTGAAGGAGTTCCAGGCACGTTACCGGCAGCTGGTGAGTGGCTCTCT GCGCACAGTGTTCGGGACTACCCCGCTCCCCATGGCCTGCCCAGCGCTGAGTGAGAGCCAGCCCAAGTTCGGCCACTTCCTCGAGTTCAT GGATGAGTTCTGCCAGGAGCCCACAGCCAGTGACTCACAAGGCTAGAGCTGTGCATGGGGGCTGTGTGCACCACCCGGCCTGTGCCCCAG CTCTCCCCGAGGGCTCTGTGCCCTGGACCGCACCTCAAGGTTGACCAGCCGGCCACAGGCCTCAGAGCTCAGCTGGGCCCCACTTGCTGG CCACAAGGTGGCATCCCCTTGTCAGGATCTCCCCTCCTTGGCCCAGGCATGACCTGGTGCCTGGCCCAGCGGCAATAAAGAGTGGGTGCA >In-frame_PPFIA1_ENST00000389547_chr11_70118542_+_XRRA1_ENST00000340360_chr11_74559507_-_4455nt GCTCCTCCTCCGCTCCGCCAGTGTCCGGCCGCGGGCCGGCCTTAGTGACTGGGGCGGCGGGCCCCGGGGCCGCGGCGTGGGGCGGGCAGG CGGACGCCGGCCGCGGGCTGCTTTCGTCGGCTCCCAAGCTCTCCCGGAGCGAGCAGCCGCCCGCGAGCCGCCGCGGAGCCTCCTCGCCCG CTCCCGCCGGCGAGCAAGATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAGGTGGAGGCCATGGTTCC GGCTCCCCTTCACAGCCAGATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACCGCCTTCTTGATACACTG AGAGAGACTCAAGAAACGCTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGCAGAGACAGCTCAACACG GCACTTCCACAGGTGAAAAGCGAAATCCCAAAGGTGCCGAAGCAGCCTCTGGTGCTCCATCACCCGCGCATGACGACAACCAAGTCTCCC TCAAAGGATATGCTAGAGCCAGAGGCAGAGCTGGCTGAAGATCTGCCCACTACCAAAAGCACTTCTGTGGAGTCAGAGATGCCCACTGAG AACCTGGAAGGCCATTCCCCGTCTTGCCGGACCTTCGTGCCACTGCCTCCCATCTGCTCCAACTCCACTGTGCATAGTGAAGAGACCCTG TCCCACCTGAGTGACACAACTGTCCGCCTCAGCCCAGAGCGCCCATCAGATGAGGACTCCAAGAGCACAGAGTCCATCTTCCTGACCCAG GTGAGTGAACTGCCTTCCTCCGTCATCCATAAGGATGATTTAGAGTTAAAGGAGAAAGACCAAAAGAAACCACCAACGGCACCCAGAGAG GTGAAAGGGACTCGGAGGAAACTCCCAACTGCCTTCCTTCCCAGCAAGTACCACGGCTATGAAGAACTGCTGACAGCCAAGCCTGATCCA GCCTTCATTGAGCCAAAGGGAATCCAGAAGAATGCACAAGCCCTGCAACAAATGCTGAAGCACCCACTCCTGTGCCACTCCTCCAAGCCC AAGCTGGACACTCTTCAGAAACCCTATGTTCACAAAGAGAAACGGGCCCAGAGAATCCCGATTCCACCCCCAAAGAAGACTAGAGCCCAA CTTCTGGATGACATCTTCATTCGCTTGCGGGATCCCCGGAACATTACAGAGGCTCCACTAGGTGCTGTCCTGCACCAGTGGACAGAACGG CGGCTGGTGAACCACAAGCAGTACCTGGAGGCCAAGAGGCTGTTGAAGGAGTTCCAGGCACGTTACCGGCAGCTGGTGAGTGGCTCTCTG CGCACAGTGTTCGGGACTACCCCGCTCCCCATGGCCTGCCCAGCGCTGAGTGAGAGCCAGCCCAAGTTCGGCCACTTCCTCGAGTTCATG GATGAGTTCTGCCAGGAGCCCACAGCCAGTGACTCACAAGGCTAGAGCTGTGCATGGGGGCTGTGTGCACCACCCGGCCTGTGCCCCAGC TCTCCCCGAGGGCTCTGTGCCCTGGACCGCACCTCAAGGTTGACCAGCCGGCCACAGGCCTCAGAGCTCAGCTGGGCCCCACTTGCTGGC CACAAGGTGGCATCCCCTTGTCAGGATCTCCCCTCCTTGGCCCAGGCATGACCTGGTGCCTGGCCCAGCGGCAATAAAGAGTGGGTGCAC AGGGCAATAGACTGGGTGCCACATGCATTCTTTCTTGGAACCCAGGCCACAGCAGCATTGTCACACTTCCCTCTAAAAATGGTTTTCCAG TTCAGATGCAACAGGGATACATTTGTTCTCTGTTGTATGAGAAACTGACACCAAGGGGATCTTAACAAATTCCTGAACAATGGCTCCAAA AAAGGGTATTTTTAAAAACCAGATCTTGTGAGTACAGCCCTAATGTGCAGGGACAGTGTCATCCTGTATATTCGTTCTTTACTCAGACTC TTTCTTGGTTCCTTCATTAGGAGCATGAATGGTTGAATGTGAACATGACAGTAAATTGGAGCAAACTGTAAACTGGACATAACTTATGCC AAAAGACGTAGTTGTACACCATGGAAACCCCATCCCTGCTCCTAATCTCTACTGCCATTCTGAATGCCAAAGCAAGACATCCAACATGGG GCATCTCCCAGAGCACATACAGCACCAAAAATCCACACACAGCCTAAGCTTAACCCATGTTTTTGTCTGAGATTGTTCACCAGAGACAAG ACTCTGACTATAAACAGAACATCCACTTTCATGAGTTTCCTTTACTGTATTCTCAACTTGGGCCTTGCTTCAAGCAGGCAAACATACATT GAAGAATGCACTTTGGTACTGTTTAAATAACAACACATCAGCCCACTTGATTCCATGCCATGTCCTTGCTGACAGAAACATCCCCAACAG GGCATGCCCTGGTCCAAGTCCTCTGTCTTTGTCAAAATGCTCTTCTGATGAGTTGGAGAGGAGGCAGCCAGCAGTGGCAGTCCACAAGGA TCCAGGTACCTTCTCCAATCCTAAAGCAGACAGCAGGTTGAATAAAACCAATACACAACCTATTTTCTAGGCAGGAGGGGAAAAGGCCCT TAGGACAATAATATTTGTACAAAGAGTTGAGAGTAAACAAACAGTGTATCAGGTTCAAAAAAAAAAAAACTATTCGTTGGCATTTAAATT TTTTTCCCTTGCATAGTATCTATTCTCTCACTAGGACTTTTAAGTGCTCTGCTGGAGGCTCAGCGTTGGTAATACCATGTTTGATGCAAA CTTGAACCCAATGCTCTCATTGGTGGCACAGCTTTGGAGGGTGGTGGCCCCAAGAAGGGGCAATCTGCCTGCTGCTATATTAATCTGGAA CCAGGGCCAACAGCTACTCTTGAACTATGGTATTTGAAGAGCGAGTTCATTGCCTGTTTTACCTTAAATGACAGGAAAGGAAGATGAACA AACCTTGCTTTGCCTTGGCTTCAAACTAGTTCTTGATTTAAGACACCAGAAAGGGAGAGAGGGAGTCTGCTTAGAGTTTGAGGTTGCCTC TCACAAGATGACAGTTAAAAGTTGCCACCTTACTTAAAAGGCATTAAGGAGGCATTTACTCACAAAGGAGAGAGAGTAAATTTTTTTCTT AAGAGGAAAAAAATACTGATAATACATAGAACAATCTGCACATCCAGTCTTGGCACTTTTTCCAATTTGACTGATCTCTAAACTGGTGAC CCTTGCATATATCTTAGTCTCTTTTCTACAATCTTCTTCAGAAAGCTACAGCAGCTAACAATCATGTATAAAGATGCATTTCCTAGATCA TCTTCAGAAGAAAATCTCTTCAGCACTTTCCCTAGAATCTGTCTCCTGACCACCCCGCCCCAGACCTGCTTTCTCTTTTGAGAATTCATA ACCAGGTATGTTTAGATACCAGTTCAAAAGACCACTCTATGGGTTGATGAGGAAAAGGCTGCCTGAGGACAATTTAAGACCATAATGAGT TTCCAATTTTTAAAGAAAATTTGGCTAGCTGGCTTTTAATTCTTAATTAAAATCATTAAATTTAATTAAAATTATTCCAATCAAAATATA TCACTTTCCAAGATTCCACATTCATATTACTTACTTATACTATGGAGACTTTCTCTACCTGAGCATGTATTCAGGGGCTATAGGTACATT TAACTCTAACTAACTGAAAAAAATCAGGAAGAAAAAACTATTAAAATAAAATAACCTCCTAAATCATTTGGGGGTATCCCCATCATTGGT GCGTGTGTCTGCGTGTGTCAAACTTTAATGATTATTTATTCAGACCCTGGAAAACCACACTATAAAATAGGGCACTGGATCACAAGTTCG TTTGGTTAAAAAAAAAAAAAAAAAAAAGTGGGGGCGGGGGGCAGAGAAGAAGTTTAACTTGGATGATTTCCATGCCCATTCCAGCTGTAA CATTCTATGACTGTGACCCAGCCTTTGTTCTCTTTTCTCACTCTCCTACTAGACATTTCAATGAAAAGTTAGGCAGGAAAAAGGAAAGGA ATCCCAAGTTGCTGCCAGCTCTGATGAGAGATCAGGTTGGGGGAGAGATTAGGTGGTTACTGAATTGAGGTGTGGGCCTCCCCTGACCAT GTCAGTGATCCACAACCCACCTCACTTCTTGGGGCTTAAGCTAAAAGCAGCTTCTGAAGAGATGTTAATGTCCTGTAATCACTAGAGGAG AAAATTCATTCTCCTTCCATAACATTACTTAGTAAAGGAAAAGCGGTGGTGCAATCAAATTCACAAATACCAATGGGGTCTCTAAAATGT AGAATGCAGCTTGCTGGGTGCTGGTCAGTTTTCTAAATGGGACCAGAAATGGCTTTCCTAAGACCATAAATGAACTCTCCAGCCACACAT >In-frame_PPFIA1_ENST00000389547_chr11_70118542_+_XRRA1_ENST00000321448_chr11_74559507_-_3775nt GCTCCTCCTCCGCTCCGCCAGTGTCCGGCCGCGGGCCGGCCTTAGTGACTGGGGCGGCGGGCCCCGGGGCCGCGGCGTGGGGCGGGCAGG CGGACGCCGGCCGCGGGCTGCTTTCGTCGGCTCCCAAGCTCTCCCGGAGCGAGCAGCCGCCCGCGAGCCGCCGCGGAGCCTCCTCGCCCG CTCCCGCCGGCGAGCAAGATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAGGTGGAGGCCATGGTTCC GGCTCCCCTTCACAGCCAGATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACCGCCTTCTTGATACACTG AGAGAGACTCAAGAAACGCTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGCAGAGACAGCTCAACACG GCACTTCCACAGGTGAAAAGCGAAATCCCAAAGGTGCCGAAGCAGCCTCTGGTGCTCCATCACCCGCGCATGACGACAACCAAGTCTCCC TCAAAGGATATGCTAGAGCCAGAGGCAGAGCTGGCTGAAGATCTGCCCACTACCAAAAGCACTTCTGTGGAGTCAGAGATGCCCACTGAG AACCTGGAAGGCCATTCCCCGTCTTGCCGGACCTTCGTGCCACTGCCTCCCATCTGCTCCAACTCCACTGTGCATAGTGAAGAGACCCTG TCCCACCTGAGTGACACAACTGTCCGCCTCAGCCCAGAGCGCCCATCAGATGAGGACTCCAAGAGCACAGAGTCCATCTTCCTGACCCAG GTGAGTGAACTGCCTTCCTCCGTCATCCATAAGGATGATTTAGAGTTAAAGGAGAAAGACCAAAAGAAACCACCAACGGCACCCAGAGAG GTGAAAGGGACTCGGAGGAAACTCCCAACTGCCTTCCTTCCCAGCAAGTACCACGGCTATGAAGAACTGCTGACAGCCAAGCCTGATCCA GCCTTCATTGAGCCAAAGGGAATCCAGAAGAATGCACAAGCCCTGCAACAAATGCTGAAGCACCCACTCCTGTGCCACTCCTCCAAGCCC AAGCTGGACACTCTTCAGAAACCCTATGTTCACAAAGAGAAACGGGCCCAGAGAATCCCGATTCCACCCCCAAAGAAGACTAGAGCCCAA CTTCTGGATGACATCTTCATTCGCTTGCGGGATCCCCGGAACATTACAGAGGCTCCACTAGGTGCTGTCCTGCACCAGTGGACAGAACGG CGGCTGGTGAACCACAAGCAGTACCTGGAGGCCAAGAGGCTGTTGAAGGAGTTCCAGGCACGTTACCGGCAGCTGGTGAGTGGCTCTCTG CGCACAGTGTTCGGGACTACCCCGCTCCCCATGGCCTGCCCAGCGCTGAGTGAGAGCCAGCCCAAGTTCGGCCACTTCCTCGAGTTCATG GATGAGTTCTGCCAGGAGCCCACAGCCAGTGACTCACAAGGCTAGAGCTGTGCATGGGGGCTGTGTGCACCACCCGGCCTGTGCCCCAGC TCTCCCCGAGGGCTCTGTGCCCTGGACCGCACCTCAAGGTTGACCAGCCGGCCACAGGCCTCAGAGCTCAGCTGGGCCCCACTTGCTGGC CACAAGGTGGCATCCCCTTGTCAGGATCTCCCCTCCTTGGCCCAGGCATGACCTGGTGCCTGGCCCAGCGGCAATAAAGAGTGGGTGCAC AGGGCAATAGACTGGGTGCCACATGCATTCTTTCTTGGAACCCAGGCCACAGCAGCATTGTCACACTTCCCTCTAAAAATGGTTTTCCAG TTCAGATGCAACAGGGATACATTTGTTCTCTGTTGTATGAGAAACTGACACCAAGGGGATCTTAACAAATTCCTGAACAATGGCTCCAAA AAAGGGTATTTTTAAAAACCAGATCTTGTGAGTACAGCCCTAATGTGCAGGGACAGTGTCATCCTGTATATTCGTTCTTTACTCAGACTC TTTCTTGGTTCCTTCATTAGGAGCATGAATGGTTGAATGTGAACATGACAGTAAATTGGAGCAAACTGTAAACTGGACATAACTTATGCC AAAAGACGTAGTTGTACACCATGGAAACCCCATCCCTGCTCCTAATCTCTACTGCCATTCTGAATGCCAAAGCAAGACATCCAACATGGG GCATCTCCCAGAGCACATACAGCACCAAAAATCCACACACAGCCTAAGCTTAACCCATGTTTTTGTCTGAGATTGTTCACCAGAGACAAG ACTCTGACTATAAACAGAACATCCACTTTCATGAGTTTCCTTTACTGTATTCTCAACTTGGGCCTTGCTTCAAGCAGGCAAACATACATT GAAGAATGCACTTTGGTACTGTTTAAATAACAACACATCAGCCCACTTGATTCCATGCCATGTCCTTGCTGACAGAAACATCCCCAACAG GGCATGCCCTGGTCCAAGTCCTCTGTCTTTGTCAAAATGCTCTTCTGATGAGTTGGAGAGGAGGCAGCCAGCAGTGGCAGTCCACAAGGA TCCAGGTACCTTCTCCAATCCTAAAGCAGACAGCAGGTTGAATAAAACCAATACACAACCTATTTTCTAGGCAGGAGGGGAAAAGGCCCT TAGGACAATAATATTTGTACAAAGAGTTGAGAGTAAACAAACAGTGTATCAGGTTCAAAAAAAAAAAAACTATTCGTTGGCATTTAAATT TTTTTCCCTTGCATAGTATCTATTCTCTCACTAGGACTTTTAAGTGCTCTGCTGGAGGCTCAGCGTTGGTAATACCATGTTTGATGCAAA CTTGAACCCAATGCTCTCATTGGTGGCACAGCTTTGGAGGGTGGTGGCCCCAAGAAGGGGCAATCTGCCTGCTGCTATATTAATCTGGAA CCAGGGCCAACAGCTACTCTTGAACTATGGTATTTGAAGAGCGAGTTCATTGCCTGTTTTACCTTAAATGACAGGAAAGGAAGATGAACA AACCTTGCTTTGCCTTGGCTTCAAACTAGTTCTTGATTTAAGACACCAGAAAGGGAGAGAGGGAGTCTGCTTAGAGTTTGAGGTTGCCTC TCACAAGATGACAGTTAAAAGTTGCCACCTTACTTAAAAGGCATTAAGGAGGCATTTACTCACAAAGGAGAGAGAGTAAATTTTTTTCTT AAGAGGAAAAAAATACTGATAATACATAGAACAATCTGCACATCCAGTCTTGGCACTTTTTCCAATTTGACTGATCTCTAAACTGGTGAC CCTTGCATATATCTTAGTCTCTTTTCTACAATCTTCTTCAGAAAGCTACAGCAGCTAACAATCATGTATAAAGATGCATTTCCTAGATCA TCTTCAGAAGAAAATCTCTTCAGCACTTTCCCTAGAATCTGTCTCCTGACCACCCCGCCCCAGACCTGCTTTCTCTTTTGAGAATTCATA ACCAGGTATGTTTAGATACCAGTTCAAAAGACCACTCTATGGGTTGATGAGGAAAAGGCTGCCTGAGGACAATTTAAGACCATAATGAGT TTCCAATTTTTAAAGAAAATTTGGCTAGCTGGCTTTTAATTCTTAATTAAAATCATTAAATTTAATTAAAATTATTCCAATCAAAATATA TCACTTTCCAAGATTCCACATTCATATTACTTACTTATACTATGGAGACTTTCTCTACCTGAGCATGTATTCAGGGGCTATAGGTACATT >In-frame_PPFIA1_ENST00000389547_chr11_70118542_+_XRRA1_ENST00000527087_chr11_74559507_-_1611nt GCTCCTCCTCCGCTCCGCCAGTGTCCGGCCGCGGGCCGGCCTTAGTGACTGGGGCGGCGGGCCCCGGGGCCGCGGCGTGGGGCGGGCAGG CGGACGCCGGCCGCGGGCTGCTTTCGTCGGCTCCCAAGCTCTCCCGGAGCGAGCAGCCGCCCGCGAGCCGCCGCGGAGCCTCCTCGCCCG CTCCCGCCGGCGAGCAAGATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAGGTGGAGGCCATGGTTCC GGCTCCCCTTCACAGCCAGATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACCGCCTTCTTGATACACTG AGAGAGACTCAAGAAACGCTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGCAGAGACAGCTCAACACG GCACTTCCACAGGTGAAAAGCGAAATCCCAAAGGTGCCGAAGCAGCCTCTGGTGCTCCATCACCCGCGCATGACGACAACCAAGTCTCCC TCAAAGGATATGCTAGAGCCAGAGGCAGAGCTGGCTGAAGATCTGCCCACTACCAAAAGCACTTCTGTGGAGTCAGAGATGCCCACTGAG AACCTGGAAGGCCATTCCCCGTCTTGCCGGACCTTCGTGCCACTGCCTCCCATCTGCTCCAACTCCACTGTGCATAGTGAAGAGACCCTG TCCCACCTGAGTGACACAACTGTCCGCCTCAGCCCAGAGCGCCCATCAGATGAGGACTCCAAGAGCACAGAGTCCATCTTCCTGACCCAG GTGAGTGAACTGCCTTCCTCCGTCATCCATAAGGATGATTTAGAGTTAAAGGAGAAAGACCAAAAGAAACCACCAACGGCACCCAGAGAG GTGAAAGGGACTCGGAGGAAACTCCCAACTGCCTTCCTTCCCAGCAAGTACCACGGCTATGAAGAACTGCTGACAGCCAAGCCTGATCCA GCCTTCATTGAGCCAAAGGGAATCCAGAAGAATGCACAAGCCCTGCAACAAATGCTGAAGCACCCACTCCTGTGCCACTCCTCCAAGCCC AAGCTGGACACTCTTCAGAAACCCTATGTTCACAAAGAGAAACGGGTGCTGTCCTGCACCAGTGGACAGAACGGCGGCTGGTGAACCACA AGCAGTACCTGGAGGCCAAGAGGCTGTTGAAGGAGTTCCAGGCACGTTACCGGCAGCTGGTGAGTGGCTCTCTGCGCACAGTGTTCGGGA CTACCCCGCTCCCCATGGCCTGCCCAGCGCTGAGTGAGAGCCAGCCCAAGTTCGGCCACTTCCTCGAGTTCATGGATGAGTTCTGCCAGG AGCCCACAGCCAGTGACTCACAAGGCTAGAGCTGTGCATGGGGGCTGTGTGCACCACCCGGCCTGTGCCCCAGCTCTCCCCGAGGGCTCT GTGCCCTGGACCGCACCTCAAGGTTGACCAGCCGGCCACAGGCCTCAGAGCTCAGCTGGGCCCCACTTGCTGGCCACAAGGTGGCATCCC |
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FusionGenePPI for PPFIA1_XRRA1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| PPFIA1 | GIT1, ERC2, PPP2R5D, TNNT1, MBIP, GRIP2, PTPRF, PTPRD, PTPRS, NCOA2, PPP2CA, PPP2R1A, PPFIA1, PPFIA2, ING4, PPP2CB, CUL2, AGTPBP1, CEP70, AMOT, LATS2, YWHAB, IKBKG, PSMC4, PSMD1, PSMD13, PSMD8, SPTAN1, DROSHA, NDN, AURKB, CDKN1A, CCNH, DTNB, FAM161A, TXLNA, BRCA1, GPS2, C16orf70, CYP4X1, NTRK1, OSBP, PPFIA3, PPFIBP1, PPFIBP2, CAGE1, TUBG1, XRCC1, GBA2, CDC5L, NF2, IL17RE, LLGL2, SERPINB2, STX11, EXOC8, TTC9B, CCDC120, TRIM25 | XRRA1 | NXF1, EGFR |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for PPFIA1_XRRA1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for PPFIA1_XRRA1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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