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Fusion gene ID: 28151 |
FusionGeneSummary for PPFIA1_SLC39A11 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PPFIA1_SLC39A11 | Fusion gene ID: 28151 | Hgene | Tgene | Gene symbol | PPFIA1 | SLC39A11 | Gene ID | 8500 | 201266 |
| Gene name | PTPRF interacting protein alpha 1 | solute carrier family 39 member 11 | |
| Synonyms | LIP.1|LIP1|LIPRIN | C17orf26|ZIP-11|ZIP11 | |
| Cytomap | 11q13.3 | 17q24.3-q25.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | liprin-alpha-1LAR-interacting protein 1LIP-1Liprin-alpha1protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | zinc transporter ZIP11Zrt- and Irt-like protein 11solute carrier family 39 (metal ion transporter), member 11 | |
| Modification date | 20180522 | 20180523 | |
| UniProtAcc | Q13136 | Q8N1S5 | |
| Ensembl transtripts involved in fusion gene | ENST00000253925, ENST00000389547, ENST00000530548, | ENST00000255559, ENST00000542342, ENST00000579988, ENST00000579732, | |
| Fusion gene scores | * DoF score | 36 X 13 X 14=6552 | 12 X 6 X 7=504 |
| # samples | 41 | 12 | |
| ** MAII score | log2(41/6552*10)=-3.99823954213556 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(12/504*10)=-2.0703893278914 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: PPFIA1 [Title/Abstract] AND SLC39A11 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | BRCA | TCGA-BH-A0DD-01A | PPFIA1 | chr11 | 70172924 | + | SLC39A11 | chr17 | 71027853 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000253925 | ENST00000255559 | PPFIA1 | chr11 | 70172924 | + | SLC39A11 | chr17 | 71027853 | - |
| In-frame | ENST00000253925 | ENST00000542342 | PPFIA1 | chr11 | 70172924 | + | SLC39A11 | chr17 | 71027853 | - |
| 5CDS-intron | ENST00000253925 | ENST00000579988 | PPFIA1 | chr11 | 70172924 | + | SLC39A11 | chr17 | 71027853 | - |
| 5CDS-intron | ENST00000253925 | ENST00000579732 | PPFIA1 | chr11 | 70172924 | + | SLC39A11 | chr17 | 71027853 | - |
| In-frame | ENST00000389547 | ENST00000255559 | PPFIA1 | chr11 | 70172924 | + | SLC39A11 | chr17 | 71027853 | - |
| In-frame | ENST00000389547 | ENST00000542342 | PPFIA1 | chr11 | 70172924 | + | SLC39A11 | chr17 | 71027853 | - |
| 5CDS-intron | ENST00000389547 | ENST00000579988 | PPFIA1 | chr11 | 70172924 | + | SLC39A11 | chr17 | 71027853 | - |
| 5CDS-intron | ENST00000389547 | ENST00000579732 | PPFIA1 | chr11 | 70172924 | + | SLC39A11 | chr17 | 71027853 | - |
| intron-3CDS | ENST00000530548 | ENST00000255559 | PPFIA1 | chr11 | 70172924 | + | SLC39A11 | chr17 | 71027853 | - |
| intron-3CDS | ENST00000530548 | ENST00000542342 | PPFIA1 | chr11 | 70172924 | + | SLC39A11 | chr17 | 71027853 | - |
| intron-intron | ENST00000530548 | ENST00000579988 | PPFIA1 | chr11 | 70172924 | + | SLC39A11 | chr17 | 71027853 | - |
| intron-intron | ENST00000530548 | ENST00000579732 | PPFIA1 | chr11 | 70172924 | + | SLC39A11 | chr17 | 71027853 | - |
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FusionProtFeatures for PPFIA1_SLC39A11 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| PPFIA1 | SLC39A11 |
| May regulate the disassembly of focal adhesions. Maylocalize receptor-like tyrosine phosphatases type 2A at specificsites on the plasma membrane, possibly regulating theirinteraction with the extracellular environment and theirassociation with substrates. {ECO:0000269|PubMed:7796809}. | Functions as a cellular zinc transporter.{ECO:0000250|UniProtKB:Q8BWY7}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | PPFIA1 | chr11:70172924 | chr17:71027853 | ENST00000253925 | + | 7 | 28 | 176_214 | 310 | 1597 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | PPFIA1 | chr11:70172924 | chr17:71027853 | ENST00000253925 | + | 7 | 28 | 34_141 | 310 | 1597 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | PPFIA1 | chr11:70172924 | chr17:71027853 | ENST00000389547 | + | 7 | 26 | 176_214 | 310 | 1186 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | PPFIA1 | chr11:70172924 | chr17:71027853 | ENST00000389547 | + | 7 | 26 | 34_141 | 310 | 1186 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | PPFIA1 | chr11:70172924 | chr17:71027853 | ENST00000253925 | + | 7 | 28 | 17_25 | 310 | 1597 | Compositional bias | Note=Poly-Gly |
| Hgene | PPFIA1 | chr11:70172924 | chr17:71027853 | ENST00000389547 | + | 7 | 26 | 17_25 | 310 | 1186 | Compositional bias | Note=Poly-Gly |
| Tgene | >SLC39A11 | chr11:70172924 | chr17:71027853 | ENST00000255559 | - | 2 | 10 | 194_214 | 49 | 336 | Transmembrane | Helical |
| Tgene | >SLC39A11 | chr11:70172924 | chr17:71027853 | ENST00000255559 | - | 2 | 10 | 263_285 | 49 | 336 | Transmembrane | Helical |
| Tgene | >SLC39A11 | chr11:70172924 | chr17:71027853 | ENST00000255559 | - | 2 | 10 | 290_307 | 49 | 336 | Transmembrane | Helical |
| Tgene | >SLC39A11 | chr11:70172924 | chr17:71027853 | ENST00000255559 | - | 2 | 10 | 322_342 | 49 | 336 | Transmembrane | Helical |
| Tgene | >SLC39A11 | chr11:70172924 | chr17:71027853 | ENST00000255559 | - | 2 | 10 | 72_92 | 49 | 336 | Transmembrane | Helical |
| Tgene | >SLC39A11 | chr11:70172924 | chr17:71027853 | ENST00000542342 | - | 2 | 10 | 194_214 | 49 | 343 | Transmembrane | Helical |
| Tgene | >SLC39A11 | chr11:70172924 | chr17:71027853 | ENST00000542342 | - | 2 | 10 | 263_285 | 49 | 343 | Transmembrane | Helical |
| Tgene | >SLC39A11 | chr11:70172924 | chr17:71027853 | ENST00000542342 | - | 2 | 10 | 290_307 | 49 | 343 | Transmembrane | Helical |
| Tgene | >SLC39A11 | chr11:70172924 | chr17:71027853 | ENST00000542342 | - | 2 | 10 | 322_342 | 49 | 343 | Transmembrane | Helical |
| Tgene | >SLC39A11 | chr11:70172924 | chr17:71027853 | ENST00000542342 | - | 2 | 10 | 72_92 | 49 | 343 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >PPFIA1 | chr11:70172924 | chr17:71027853 | ENST00000253925 | + | 7 | 28 | 1021_1050 | 310 | 1597 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >PPFIA1 | chr11:70172924 | chr17:71027853 | ENST00000253925 | + | 7 | 28 | 249_521 | 310 | 1597 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >PPFIA1 | chr11:70172924 | chr17:71027853 | ENST00000253925 | + | 7 | 28 | 623_669 | 310 | 1597 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >PPFIA1 | chr11:70172924 | chr17:71027853 | ENST00000253925 | + | 7 | 28 | 847_871 | 310 | 1597 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >PPFIA1 | chr11:70172924 | chr17:71027853 | ENST00000389547 | + | 7 | 26 | 1021_1050 | 310 | 1186 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >PPFIA1 | chr11:70172924 | chr17:71027853 | ENST00000389547 | + | 7 | 26 | 249_521 | 310 | 1186 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >PPFIA1 | chr11:70172924 | chr17:71027853 | ENST00000389547 | + | 7 | 26 | 623_669 | 310 | 1186 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >PPFIA1 | chr11:70172924 | chr17:71027853 | ENST00000389547 | + | 7 | 26 | 847_871 | 310 | 1186 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >PPFIA1 | chr11:70172924 | chr17:71027853 | ENST00000253925 | + | 7 | 28 | 1051_1120 | 310 | 1597 | Domain | SAM 3 |
| Hgene | >PPFIA1 | chr11:70172924 | chr17:71027853 | ENST00000253925 | + | 7 | 28 | 878_944 | 310 | 1597 | Domain | SAM 1 |
| Hgene | >PPFIA1 | chr11:70172924 | chr17:71027853 | ENST00000253925 | + | 7 | 28 | 963_1027 | 310 | 1597 | Domain | SAM 2 |
| Hgene | >PPFIA1 | chr11:70172924 | chr17:71027853 | ENST00000389547 | + | 7 | 26 | 1051_1120 | 310 | 1186 | Domain | SAM 3 |
| Hgene | >PPFIA1 | chr11:70172924 | chr17:71027853 | ENST00000389547 | + | 7 | 26 | 878_944 | 310 | 1186 | Domain | SAM 1 |
| Hgene | >PPFIA1 | chr11:70172924 | chr17:71027853 | ENST00000389547 | + | 7 | 26 | 963_1027 | 310 | 1186 | Domain | SAM 2 |
| Tgene | SLC39A11 | chr11:70172924 | chr17:71027853 | ENST00000255559 | - | 2 | 10 | 12_32 | 49 | 336 | Transmembrane | Helical |
| Tgene | SLC39A11 | chr11:70172924 | chr17:71027853 | ENST00000255559 | - | 2 | 10 | 44_64 | 49 | 336 | Transmembrane | Helical |
| Tgene | SLC39A11 | chr11:70172924 | chr17:71027853 | ENST00000542342 | - | 2 | 10 | 12_32 | 49 | 343 | Transmembrane | Helical |
| Tgene | SLC39A11 | chr11:70172924 | chr17:71027853 | ENST00000542342 | - | 2 | 10 | 44_64 | 49 | 343 | Transmembrane | Helical |
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FusionGeneSequence for PPFIA1_SLC39A11 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_PPFIA1_ENST00000253925_chr11_70172924_+_SLC39A11_ENST00000255559_chr17_71027853_-_597aa MMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLMVSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQEF AALTKELNVCREQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPAGVSSEVEVLKALKSLFEHHKALDEKVRE RLRVALERCSLLEEELGATHKELMILKEQNNQKKTLTDGVLDINHEQENTPSTSGKRSSDGSLSHEEDLAKVIELQEIISKQSREQSQMK ERLASLSSHVTELEEDLDTARKDLIKSEEMNTKLQRDVREVMLAASYWSLLAPAVEMATSSGGFGAFAFFPVAVGFTLGAAFVYLADLLM PHLGAAEDPQTTLALNFGSTLMKKKSDPEGPALLFPESELSIRIDKSENGEAYQRKKAAATGLPEGPAVPVPSRGNLAQPGGSSWRRIAL LILAITIHNVPEGLAVGVGFGAIEKTASATFESARNLAIGIGIQNFPEGLAVSLPLRGAGFSTWRAFWYGQLSGMVEPLAGVFGAFAVVL >In-frame_PPFIA1_ENST00000253925_chr11_70172924_+_SLC39A11_ENST00000542342_chr17_71027853_-_604aa MMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLMVSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQEF AALTKELNVCREQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPAGVSSEVEVLKALKSLFEHHKALDEKVRE RLRVALERCSLLEEELGATHKELMILKEQNNQKKTLTDGVLDINHEQENTPSTSGKRSSDGSLSHEEDLAKVIELQEIISKQSREQSQMK ERLASLSSHVTELEEDLDTARKDLIKSEEMNTKLQRDVREVMLAASYWSLLAPAVEMATSSGGFGAFAFFPVAVGFTLGAAFVYLADLLM PHLGAAEDPQTTLALNFGSTLMKKKSDPEGPALLFPESELSIRIGRAGLLSDKSENGEAYQRKKAAATGLPEGPAVPVPSRGNLAQPGGS SWRRIALLILAITIHNVPEGLAVGVGFGAIEKTASATFESARNLAIGIGIQNFPEGLAVSLPLRGAGFSTWRAFWYGQLSGMVEPLAGVF >In-frame_PPFIA1_ENST00000389547_chr11_70172924_+_SLC39A11_ENST00000255559_chr17_71027853_-_597aa MMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLMVSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQEF AALTKELNVCREQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPAGVSSEVEVLKALKSLFEHHKALDEKVRE RLRVALERCSLLEEELGATHKELMILKEQNNQKKTLTDGVLDINHEQENTPSTSGKRSSDGSLSHEEDLAKVIELQEIISKQSREQSQMK ERLASLSSHVTELEEDLDTARKDLIKSEEMNTKLQRDVREVMLAASYWSLLAPAVEMATSSGGFGAFAFFPVAVGFTLGAAFVYLADLLM PHLGAAEDPQTTLALNFGSTLMKKKSDPEGPALLFPESELSIRIDKSENGEAYQRKKAAATGLPEGPAVPVPSRGNLAQPGGSSWRRIAL LILAITIHNVPEGLAVGVGFGAIEKTASATFESARNLAIGIGIQNFPEGLAVSLPLRGAGFSTWRAFWYGQLSGMVEPLAGVFGAFAVVL >In-frame_PPFIA1_ENST00000389547_chr11_70172924_+_SLC39A11_ENST00000542342_chr17_71027853_-_604aa MMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLMVSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQEF AALTKELNVCREQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPAGVSSEVEVLKALKSLFEHHKALDEKVRE RLRVALERCSLLEEELGATHKELMILKEQNNQKKTLTDGVLDINHEQENTPSTSGKRSSDGSLSHEEDLAKVIELQEIISKQSREQSQMK ERLASLSSHVTELEEDLDTARKDLIKSEEMNTKLQRDVREVMLAASYWSLLAPAVEMATSSGGFGAFAFFPVAVGFTLGAAFVYLADLLM PHLGAAEDPQTTLALNFGSTLMKKKSDPEGPALLFPESELSIRIGRAGLLSDKSENGEAYQRKKAAATGLPEGPAVPVPSRGNLAQPGGS SWRRIALLILAITIHNVPEGLAVGVGFGAIEKTASATFESARNLAIGIGIQNFPEGLAVSLPLRGAGFSTWRAFWYGQLSGMVEPLAGVF |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_PPFIA1_ENST00000253925_chr11_70172924_+_SLC39A11_ENST00000255559_chr17_71027853_-_1791nt ATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAGGTGGAGGCCATGGTTCCGGCTCCCCTTCACAGCCA GATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACCGCCTTCTTGATACACTGAGAGAGACTCAAGAAACG CTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGCAGAGACAGCTCAACACGGCACTTCCACAGGAGTTC GCAGCACTTACTAAAGAACTCAATGTATGCAGGGAACAGCTCCTTGAAAGGGAAGAAGAAATTGCTGAACTGAAAGCAGAAAGGAATAAC ACCAGGCTGCTGTTAGAGCATTTGGAATGCCTTGTCTCCAGGCATGAGCGGTCTCTTAGGATGACCGTGGTGAAGAGACAAGCGCAGTCT CCAGCAGGCGTGTCCAGCGAAGTGGAAGTGCTGAAAGCACTGAAGTCCTTATTTGAACACCACAAAGCTCTGGATGAAAAGGTGAGAGAG CGATTACGAGTAGCACTTGAAAGATGTAGTTTGTTAGAAGAGGAATTAGGTGCCACACACAAAGAGCTAATGATTCTTAAAGAACAGAAT AATCAGAAAAAAACTCTAACAGATGGAGTGCTGGACATAAACCATGAACAAGAAAATACACCAAGCACGAGTGGAAAGAGATCTTCTGAT GGTTCTTTAAGCCACGAGGAAGACCTTGCTAAAGTAATTGAGCTCCAAGAAATCATAAGTAAGCAGTCAAGGGAACAGAGCCAAATGAAA GAACGCCTGGCTTCCCTTTCCAGTCATGTGACAGAACTGGAAGAGGATCTGGACACGGCTAGAAAAGATCTCATCAAATCTGAAGAAATG AACACAAAATTGCAACGAGATGTCCGTGAAGTCATGTTGGCAGCTTCCTATTGGTCTCTTCTGGCCCCAGCAGTTGAGATGGCCACGTCC TCTGGGGGCTTCGGTGCCTTTGCCTTCTTCCCTGTGGCTGTTGGCTTCACCCTTGGAGCGGCTTTTGTCTACTTGGCTGACCTCCTGATG CCTCACTTGGGTGCAGCAGAAGACCCCCAGACGACCCTGGCACTGAACTTCGGCTCTACGTTGATGAAGAAGAAGTCTGATCCTGAGGGT CCCGCGCTGCTCTTCCCTGAGAGTGAACTTTCCATCCGGATAGACAAGAGTGAGAATGGTGAGGCATATCAGAGAAAGAAGGCGGCAGCC ACTGGCCTTCCAGAGGGTCCTGCTGTCCCTGTGCCTTCTCGAGGGAATCTGGCACAGCCCGGCGGCAGCAGCTGGAGGAGGATCGCACTG CTCATCTTGGCCATCACTATACACAACGTTCCAGAGGGTCTCGCTGTTGGAGTTGGATTTGGGGCTATAGAAAAGACGGCATCTGCTACC TTTGAGAGTGCCAGGAATTTGGCCATTGGAATCGGGATCCAGAATTTCCCCGAGGGCCTGGCTGTCAGCCTTCCCTTGCGAGGGGCAGGC TTCTCCACCTGGAGAGCTTTCTGGTATGGGCAGCTGAGCGGCATGGTGGAGCCCCTGGCCGGGGTCTTTGGTGCCTTTGCCGTGGTGCTG GCTGAGCCCATCCTGCCCTACGCTCTGGCCTTTGCTGCCGGTGCCATGGTCTACGTGGTCATGGACGACATCATCCCCGAAGCCCAGATC >In-frame_PPFIA1_ENST00000253925_chr11_70172924_+_SLC39A11_ENST00000542342_chr17_71027853_-_1812nt ATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAGGTGGAGGCCATGGTTCCGGCTCCCCTTCACAGCCA GATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACCGCCTTCTTGATACACTGAGAGAGACTCAAGAAACG CTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGCAGAGACAGCTCAACACGGCACTTCCACAGGAGTTC GCAGCACTTACTAAAGAACTCAATGTATGCAGGGAACAGCTCCTTGAAAGGGAAGAAGAAATTGCTGAACTGAAAGCAGAAAGGAATAAC ACCAGGCTGCTGTTAGAGCATTTGGAATGCCTTGTCTCCAGGCATGAGCGGTCTCTTAGGATGACCGTGGTGAAGAGACAAGCGCAGTCT CCAGCAGGCGTGTCCAGCGAAGTGGAAGTGCTGAAAGCACTGAAGTCCTTATTTGAACACCACAAAGCTCTGGATGAAAAGGTGAGAGAG CGATTACGAGTAGCACTTGAAAGATGTAGTTTGTTAGAAGAGGAATTAGGTGCCACACACAAAGAGCTAATGATTCTTAAAGAACAGAAT AATCAGAAAAAAACTCTAACAGATGGAGTGCTGGACATAAACCATGAACAAGAAAATACACCAAGCACGAGTGGAAAGAGATCTTCTGAT GGTTCTTTAAGCCACGAGGAAGACCTTGCTAAAGTAATTGAGCTCCAAGAAATCATAAGTAAGCAGTCAAGGGAACAGAGCCAAATGAAA GAACGCCTGGCTTCCCTTTCCAGTCATGTGACAGAACTGGAAGAGGATCTGGACACGGCTAGAAAAGATCTCATCAAATCTGAAGAAATG AACACAAAATTGCAACGAGATGTCCGTGAAGTCATGTTGGCAGCTTCCTATTGGTCTCTTCTGGCCCCAGCAGTTGAGATGGCCACGTCC TCTGGGGGCTTCGGTGCCTTTGCCTTCTTCCCTGTGGCTGTTGGCTTCACCCTTGGAGCGGCTTTTGTCTACTTGGCTGACCTCCTGATG CCTCACTTGGGTGCAGCAGAAGACCCCCAGACGACCCTGGCACTGAACTTCGGCTCTACGTTGATGAAGAAGAAGTCTGATCCTGAGGGT CCCGCGCTGCTCTTCCCTGAGAGTGAACTTTCCATCCGGATAGGTAGAGCTGGGCTTCTTTCAGACAAGAGTGAGAATGGTGAGGCATAT CAGAGAAAGAAGGCGGCAGCCACTGGCCTTCCAGAGGGTCCTGCTGTCCCTGTGCCTTCTCGAGGGAATCTGGCACAGCCCGGCGGCAGC AGCTGGAGGAGGATCGCACTGCTCATCTTGGCCATCACTATACACAACGTTCCAGAGGGTCTCGCTGTTGGAGTTGGATTTGGGGCTATA GAAAAGACGGCATCTGCTACCTTTGAGAGTGCCAGGAATTTGGCCATTGGAATCGGGATCCAGAATTTCCCCGAGGGCCTGGCTGTCAGC CTTCCCTTGCGAGGGGCAGGCTTCTCCACCTGGAGAGCTTTCTGGTATGGGCAGCTGAGCGGCATGGTGGAGCCCCTGGCCGGGGTCTTT GGTGCCTTTGCCGTGGTGCTGGCTGAGCCCATCCTGCCCTACGCTCTGGCCTTTGCTGCCGGTGCCATGGTCTACGTGGTCATGGACGAC ATCATCCCCGAAGCCCAGATCAGTGGTAATGGGAAACTGGCATCCTGGGCCTCCATCCTGGGATTTGTAGTGATGATGTCACTGGACGTT >In-frame_PPFIA1_ENST00000389547_chr11_70172924_+_SLC39A11_ENST00000255559_chr17_71027853_-_1791nt ATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAGGTGGAGGCCATGGTTCCGGCTCCCCTTCACAGCCA GATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACCGCCTTCTTGATACACTGAGAGAGACTCAAGAAACG CTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGCAGAGACAGCTCAACACGGCACTTCCACAGGAGTTC GCAGCACTTACTAAAGAACTCAATGTATGCAGGGAACAGCTCCTTGAAAGGGAAGAAGAAATTGCTGAACTGAAAGCAGAAAGGAATAAC ACCAGGCTGCTGTTAGAGCATTTGGAATGCCTTGTCTCCAGGCATGAGCGGTCTCTTAGGATGACCGTGGTGAAGAGACAAGCGCAGTCT CCAGCAGGCGTGTCCAGCGAAGTGGAAGTGCTGAAAGCACTGAAGTCCTTATTTGAACACCACAAAGCTCTGGATGAAAAGGTGAGAGAG CGATTACGAGTAGCACTTGAAAGATGTAGTTTGTTAGAAGAGGAATTAGGTGCCACACACAAAGAGCTAATGATTCTTAAAGAACAGAAT AATCAGAAAAAAACTCTAACAGATGGAGTGCTGGACATAAACCATGAACAAGAAAATACACCAAGCACGAGTGGAAAGAGATCTTCTGAT GGTTCTTTAAGCCACGAGGAAGACCTTGCTAAAGTAATTGAGCTCCAAGAAATCATAAGTAAGCAGTCAAGGGAACAGAGCCAAATGAAA GAACGCCTGGCTTCCCTTTCCAGTCATGTGACAGAACTGGAAGAGGATCTGGACACGGCTAGAAAAGATCTCATCAAATCTGAAGAAATG AACACAAAATTGCAACGAGATGTCCGTGAAGTCATGTTGGCAGCTTCCTATTGGTCTCTTCTGGCCCCAGCAGTTGAGATGGCCACGTCC TCTGGGGGCTTCGGTGCCTTTGCCTTCTTCCCTGTGGCTGTTGGCTTCACCCTTGGAGCGGCTTTTGTCTACTTGGCTGACCTCCTGATG CCTCACTTGGGTGCAGCAGAAGACCCCCAGACGACCCTGGCACTGAACTTCGGCTCTACGTTGATGAAGAAGAAGTCTGATCCTGAGGGT CCCGCGCTGCTCTTCCCTGAGAGTGAACTTTCCATCCGGATAGACAAGAGTGAGAATGGTGAGGCATATCAGAGAAAGAAGGCGGCAGCC ACTGGCCTTCCAGAGGGTCCTGCTGTCCCTGTGCCTTCTCGAGGGAATCTGGCACAGCCCGGCGGCAGCAGCTGGAGGAGGATCGCACTG CTCATCTTGGCCATCACTATACACAACGTTCCAGAGGGTCTCGCTGTTGGAGTTGGATTTGGGGCTATAGAAAAGACGGCATCTGCTACC TTTGAGAGTGCCAGGAATTTGGCCATTGGAATCGGGATCCAGAATTTCCCCGAGGGCCTGGCTGTCAGCCTTCCCTTGCGAGGGGCAGGC TTCTCCACCTGGAGAGCTTTCTGGTATGGGCAGCTGAGCGGCATGGTGGAGCCCCTGGCCGGGGTCTTTGGTGCCTTTGCCGTGGTGCTG GCTGAGCCCATCCTGCCCTACGCTCTGGCCTTTGCTGCCGGTGCCATGGTCTACGTGGTCATGGACGACATCATCCCCGAAGCCCAGATC >In-frame_PPFIA1_ENST00000389547_chr11_70172924_+_SLC39A11_ENST00000542342_chr17_71027853_-_1812nt ATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAGGTGGAGGCCATGGTTCCGGCTCCCCTTCACAGCCA GATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACCGCCTTCTTGATACACTGAGAGAGACTCAAGAAACG CTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGCAGAGACAGCTCAACACGGCACTTCCACAGGAGTTC GCAGCACTTACTAAAGAACTCAATGTATGCAGGGAACAGCTCCTTGAAAGGGAAGAAGAAATTGCTGAACTGAAAGCAGAAAGGAATAAC ACCAGGCTGCTGTTAGAGCATTTGGAATGCCTTGTCTCCAGGCATGAGCGGTCTCTTAGGATGACCGTGGTGAAGAGACAAGCGCAGTCT CCAGCAGGCGTGTCCAGCGAAGTGGAAGTGCTGAAAGCACTGAAGTCCTTATTTGAACACCACAAAGCTCTGGATGAAAAGGTGAGAGAG CGATTACGAGTAGCACTTGAAAGATGTAGTTTGTTAGAAGAGGAATTAGGTGCCACACACAAAGAGCTAATGATTCTTAAAGAACAGAAT AATCAGAAAAAAACTCTAACAGATGGAGTGCTGGACATAAACCATGAACAAGAAAATACACCAAGCACGAGTGGAAAGAGATCTTCTGAT GGTTCTTTAAGCCACGAGGAAGACCTTGCTAAAGTAATTGAGCTCCAAGAAATCATAAGTAAGCAGTCAAGGGAACAGAGCCAAATGAAA GAACGCCTGGCTTCCCTTTCCAGTCATGTGACAGAACTGGAAGAGGATCTGGACACGGCTAGAAAAGATCTCATCAAATCTGAAGAAATG AACACAAAATTGCAACGAGATGTCCGTGAAGTCATGTTGGCAGCTTCCTATTGGTCTCTTCTGGCCCCAGCAGTTGAGATGGCCACGTCC TCTGGGGGCTTCGGTGCCTTTGCCTTCTTCCCTGTGGCTGTTGGCTTCACCCTTGGAGCGGCTTTTGTCTACTTGGCTGACCTCCTGATG CCTCACTTGGGTGCAGCAGAAGACCCCCAGACGACCCTGGCACTGAACTTCGGCTCTACGTTGATGAAGAAGAAGTCTGATCCTGAGGGT CCCGCGCTGCTCTTCCCTGAGAGTGAACTTTCCATCCGGATAGGTAGAGCTGGGCTTCTTTCAGACAAGAGTGAGAATGGTGAGGCATAT CAGAGAAAGAAGGCGGCAGCCACTGGCCTTCCAGAGGGTCCTGCTGTCCCTGTGCCTTCTCGAGGGAATCTGGCACAGCCCGGCGGCAGC AGCTGGAGGAGGATCGCACTGCTCATCTTGGCCATCACTATACACAACGTTCCAGAGGGTCTCGCTGTTGGAGTTGGATTTGGGGCTATA GAAAAGACGGCATCTGCTACCTTTGAGAGTGCCAGGAATTTGGCCATTGGAATCGGGATCCAGAATTTCCCCGAGGGCCTGGCTGTCAGC CTTCCCTTGCGAGGGGCAGGCTTCTCCACCTGGAGAGCTTTCTGGTATGGGCAGCTGAGCGGCATGGTGGAGCCCCTGGCCGGGGTCTTT GGTGCCTTTGCCGTGGTGCTGGCTGAGCCCATCCTGCCCTACGCTCTGGCCTTTGCTGCCGGTGCCATGGTCTACGTGGTCATGGACGAC ATCATCCCCGAAGCCCAGATCAGTGGTAATGGGAAACTGGCATCCTGGGCCTCCATCCTGGGATTTGTAGTGATGATGTCACTGGACGTT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_PPFIA1_ENST00000253925_chr11_70172924_+_SLC39A11_ENST00000255559_chr17_71027853_-_3641nt GCCGCGCAGCCGGGCCCGCTCCTCCTCCGCTCCGCCAGTGTCCGGCCGCGGGCCGGCCTTAGTGACTGGGGCGGCGGGCCCCGGGGCCGC GGCGTGGGGCGGGCAGGCGGACGCCGGCCGCGGGCTGCTTTCGTCGGCTCCCAAGCTCTCCCGGAGCGAGCAGCCGCCCGCGAGCCGCCG CGGAGCCTCCTCGCCCGCTCCCGCCGGCGAGCAAGATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAG GTGGAGGCCATGGTTCCGGCTCCCCTTCACAGCCAGATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACC GCCTTCTTGATACACTGAGAGAGACTCAAGAAACGCTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGC AGAGACAGCTCAACACGGCACTTCCACAGGAGTTCGCAGCACTTACTAAAGAACTCAATGTATGCAGGGAACAGCTCCTTGAAAGGGAAG AAGAAATTGCTGAACTGAAAGCAGAAAGGAATAACACCAGGCTGCTGTTAGAGCATTTGGAATGCCTTGTCTCCAGGCATGAGCGGTCTC TTAGGATGACCGTGGTGAAGAGACAAGCGCAGTCTCCAGCAGGCGTGTCCAGCGAAGTGGAAGTGCTGAAAGCACTGAAGTCCTTATTTG AACACCACAAAGCTCTGGATGAAAAGGTGAGAGAGCGATTACGAGTAGCACTTGAAAGATGTAGTTTGTTAGAAGAGGAATTAGGTGCCA CACACAAAGAGCTAATGATTCTTAAAGAACAGAATAATCAGAAAAAAACTCTAACAGATGGAGTGCTGGACATAAACCATGAACAAGAAA ATACACCAAGCACGAGTGGAAAGAGATCTTCTGATGGTTCTTTAAGCCACGAGGAAGACCTTGCTAAAGTAATTGAGCTCCAAGAAATCA TAAGTAAGCAGTCAAGGGAACAGAGCCAAATGAAAGAACGCCTGGCTTCCCTTTCCAGTCATGTGACAGAACTGGAAGAGGATCTGGACA CGGCTAGAAAAGATCTCATCAAATCTGAAGAAATGAACACAAAATTGCAACGAGATGTCCGTGAAGTCATGTTGGCAGCTTCCTATTGGT CTCTTCTGGCCCCAGCAGTTGAGATGGCCACGTCCTCTGGGGGCTTCGGTGCCTTTGCCTTCTTCCCTGTGGCTGTTGGCTTCACCCTTG GAGCGGCTTTTGTCTACTTGGCTGACCTCCTGATGCCTCACTTGGGTGCAGCAGAAGACCCCCAGACGACCCTGGCACTGAACTTCGGCT CTACGTTGATGAAGAAGAAGTCTGATCCTGAGGGTCCCGCGCTGCTCTTCCCTGAGAGTGAACTTTCCATCCGGATAGACAAGAGTGAGA ATGGTGAGGCATATCAGAGAAAGAAGGCGGCAGCCACTGGCCTTCCAGAGGGTCCTGCTGTCCCTGTGCCTTCTCGAGGGAATCTGGCAC AGCCCGGCGGCAGCAGCTGGAGGAGGATCGCACTGCTCATCTTGGCCATCACTATACACAACGTTCCAGAGGGTCTCGCTGTTGGAGTTG GATTTGGGGCTATAGAAAAGACGGCATCTGCTACCTTTGAGAGTGCCAGGAATTTGGCCATTGGAATCGGGATCCAGAATTTCCCCGAGG GCCTGGCTGTCAGCCTTCCCTTGCGAGGGGCAGGCTTCTCCACCTGGAGAGCTTTCTGGTATGGGCAGCTGAGCGGCATGGTGGAGCCCC TGGCCGGGGTCTTTGGTGCCTTTGCCGTGGTGCTGGCTGAGCCCATCCTGCCCTACGCTCTGGCCTTTGCTGCCGGTGCCATGGTCTACG TGGTCATGGACGACATCATCCCCGAAGCCCAGATCAGTGGTAATGGGAAACTGGCATCCTGGGCCTCCATCCTGGGATTTGTAGTGATGA TGTCACTGGACGTTGGCCTGGGCTAGGGCTGAGACGCTTCGGACCCCGGGAAAGGCCATACGAAGAAACAGCAGTGGTTGGCTTCTATGG GACAACAAGCTTCTTTCTTCACATTAAAACTTTTTTCCTTCCTCTCTTCTTCATCTCATTATCCTGATTGACTCTGATTATAATAGAACC ATTTTTACTTTGCTTTGAGGGAGATTTTTGATTTAATGGGGAATTTTAAGGTGTCATGGAAATACAGATTCTTTGTTTTGGCCACTGAAT GGACTCTCTCTTCAGTGGGATTATCAAGGAACTTCAGATCAGGGAAATCTCCACTTCGGGACCTTCTATCTGCCTCCCAACTCCTCAAGG TCACCTATAGAAGCGAGCTACCAAAAGACGTCTCCTAAGCATTTTGGTGGCCTAGTGACTCAGGGCAGAGTGGCCAGCACACCTCTCATC CGCCCCTCCTGCTCCATCACTGCTGAGCCTCTCCCCATCTAGAATGTTGGAACTGGAGCATCATAAAGATAGCAAGCTACCTTCCAAGGC CGAGCCAGCCCAGAGAGGAGCATGTCTTCCTTTACCTCCCCCTAAGGAGATACTACATGGGAGGGGGACACAGAAAAAGGGAAGGAAATT GGCTAGTCTGGCTTTTTTTTTTTTTTTTTTTAAAGGCAAAGATTGACATTATTGAAGGAAAGGGGATGAGGACAACTGTGAACTCACAGT GAGCCCTGTGGAAAGAAGAGACAGACAGAGTGTGGGTTTGTTCGGAGGCCTCTGCTGTCAATGGATTCCAGGAGCAAGGCCATTTGTCGC GCTTTCCAAATTTCTTAGGCATTTATTTTGATAAGTTTATAGCCATCATGTTTCTAAGAGACTTGGAGACACCAGCAAACTGCTAGAACT CAAACTCTTCAATTACTCAAAGAAGGAGCCATTTCAGTTAACTCAAGTGAATGAAAGAGTTTTGGAATCTGCTGTGGGTCCTTCCCTGTT GACCATTTGGTAACTTATAATCTGACAAAAACTCTTGAGCTGCAACAGGCCTTGCCAGAGGGCTCAGGATGGGAAAGGAAGAAGGGGATA GGAAAAGAAGAGGTAATTTTACATTTCCCCTTTAAAGTAAATTTTAGCCAACTCATCATTCTGAAATGTCCCTATAAAGAATGAGTCGAA CTAGACCAGAAGCCAGCCTACTCCTTCTTACATAGCTTCTCCAACAGGGGTAGCAATGACCTGTCCACTTCAAACACAGATAAGGCCTGC CATCCTCATTGGTTAAAGGCACACGTGAGACTTTCAGTGGGCTCTGCTGAGAAGGAAGGCAGCCCAGGAGTCAGGTATGCAGGCATTGCA TTGTCAGTGTCTGCTCTCAGAGTTTACACATTCAATTGCTTCCAAGGGTGAATCTCCTGCTCTGTGAATGCTATCAGACCCCAAAGGCCA ACCTTGGGCTGGGTCTATGTACGTTCTTCCGAAGCACTGATGATCAAAATTGAAGACACATTCAGAGGTTTGATTGGTTGAGATTAACTG GTGTGGTGGTTGGTGTATGTATGTTTTATTTTTATGTCTTTGTATGTAGTTCTACATAATGCAAATTGTGCTTTCTGATGGACAAGACCT >In-frame_PPFIA1_ENST00000253925_chr11_70172924_+_SLC39A11_ENST00000542342_chr17_71027853_-_3661nt GCCGCGCAGCCGGGCCCGCTCCTCCTCCGCTCCGCCAGTGTCCGGCCGCGGGCCGGCCTTAGTGACTGGGGCGGCGGGCCCCGGGGCCGC GGCGTGGGGCGGGCAGGCGGACGCCGGCCGCGGGCTGCTTTCGTCGGCTCCCAAGCTCTCCCGGAGCGAGCAGCCGCCCGCGAGCCGCCG CGGAGCCTCCTCGCCCGCTCCCGCCGGCGAGCAAGATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAG GTGGAGGCCATGGTTCCGGCTCCCCTTCACAGCCAGATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACC GCCTTCTTGATACACTGAGAGAGACTCAAGAAACGCTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGC AGAGACAGCTCAACACGGCACTTCCACAGGAGTTCGCAGCACTTACTAAAGAACTCAATGTATGCAGGGAACAGCTCCTTGAAAGGGAAG AAGAAATTGCTGAACTGAAAGCAGAAAGGAATAACACCAGGCTGCTGTTAGAGCATTTGGAATGCCTTGTCTCCAGGCATGAGCGGTCTC TTAGGATGACCGTGGTGAAGAGACAAGCGCAGTCTCCAGCAGGCGTGTCCAGCGAAGTGGAAGTGCTGAAAGCACTGAAGTCCTTATTTG AACACCACAAAGCTCTGGATGAAAAGGTGAGAGAGCGATTACGAGTAGCACTTGAAAGATGTAGTTTGTTAGAAGAGGAATTAGGTGCCA CACACAAAGAGCTAATGATTCTTAAAGAACAGAATAATCAGAAAAAAACTCTAACAGATGGAGTGCTGGACATAAACCATGAACAAGAAA ATACACCAAGCACGAGTGGAAAGAGATCTTCTGATGGTTCTTTAAGCCACGAGGAAGACCTTGCTAAAGTAATTGAGCTCCAAGAAATCA TAAGTAAGCAGTCAAGGGAACAGAGCCAAATGAAAGAACGCCTGGCTTCCCTTTCCAGTCATGTGACAGAACTGGAAGAGGATCTGGACA CGGCTAGAAAAGATCTCATCAAATCTGAAGAAATGAACACAAAATTGCAACGAGATGTCCGTGAAGTCATGTTGGCAGCTTCCTATTGGT CTCTTCTGGCCCCAGCAGTTGAGATGGCCACGTCCTCTGGGGGCTTCGGTGCCTTTGCCTTCTTCCCTGTGGCTGTTGGCTTCACCCTTG GAGCGGCTTTTGTCTACTTGGCTGACCTCCTGATGCCTCACTTGGGTGCAGCAGAAGACCCCCAGACGACCCTGGCACTGAACTTCGGCT CTACGTTGATGAAGAAGAAGTCTGATCCTGAGGGTCCCGCGCTGCTCTTCCCTGAGAGTGAACTTTCCATCCGGATAGGTAGAGCTGGGC TTCTTTCAGACAAGAGTGAGAATGGTGAGGCATATCAGAGAAAGAAGGCGGCAGCCACTGGCCTTCCAGAGGGTCCTGCTGTCCCTGTGC CTTCTCGAGGGAATCTGGCACAGCCCGGCGGCAGCAGCTGGAGGAGGATCGCACTGCTCATCTTGGCCATCACTATACACAACGTTCCAG AGGGTCTCGCTGTTGGAGTTGGATTTGGGGCTATAGAAAAGACGGCATCTGCTACCTTTGAGAGTGCCAGGAATTTGGCCATTGGAATCG GGATCCAGAATTTCCCCGAGGGCCTGGCTGTCAGCCTTCCCTTGCGAGGGGCAGGCTTCTCCACCTGGAGAGCTTTCTGGTATGGGCAGC TGAGCGGCATGGTGGAGCCCCTGGCCGGGGTCTTTGGTGCCTTTGCCGTGGTGCTGGCTGAGCCCATCCTGCCCTACGCTCTGGCCTTTG CTGCCGGTGCCATGGTCTACGTGGTCATGGACGACATCATCCCCGAAGCCCAGATCAGTGGTAATGGGAAACTGGCATCCTGGGCCTCCA TCCTGGGATTTGTAGTGATGATGTCACTGGACGTTGGCCTGGGCTAGGGCTGAGACGCTTCGGACCCCGGGAAAGGCCATACGAAGAAAC AGCAGTGGTTGGCTTCTATGGGACAACAAGCTTCTTTCTTCACATTAAAACTTTTTTCCTTCCTCTCTTCTTCATCTCATTATCCTGATT GACTCTGATTATAATAGAACCATTTTTACTTTGCTTTGAGGGAGATTTTTGATTTAATGGGGAATTTTAAGGTGTCATGGAAATACAGAT TCTTTGTTTTGGCCACTGAATGGACTCTCTCTTCAGTGGGATTATCAAGGAACTTCAGATCAGGGAAATCTCCACTTCGGGACCTTCTAT CTGCCTCCCAACTCCTCAAGGTCACCTATAGAAGCGAGCTACCAAAAGACGTCTCCTAAGCATTTTGGTGGCCTAGTGACTCAGGGCAGA GTGGCCAGCACACCTCTCATCCGCCCCTCCTGCTCCATCACTGCTGAGCCTCTCCCCATCTAGAATGTTGGAACTGGAGCATCATAAAGA TAGCAAGCTACCTTCCAAGGCCGAGCCAGCCCAGAGAGGAGCATGTCTTCCTTTACCTCCCCCTAAGGAGATACTACATGGGAGGGGGAC ACAGAAAAAGGGAAGGAAATTGGCTAGTCTGGCTTTTTTTTTTTTTTTTTTTAAAGGCAAAGATTGACATTATTGAAGGAAAGGGGATGA GGACAACTGTGAACTCACAGTGAGCCCTGTGGAAAGAAGAGACAGACAGAGTGTGGGTTTGTTCGGAGGCCTCTGCTGTCAATGGATTCC AGGAGCAAGGCCATTTGTCGCGCTTTCCAAATTTCTTAGGCATTTATTTTGATAAGTTTATAGCCATCATGTTTCTAAGAGACTTGGAGA CACCAGCAAACTGCTAGAACTCAAACTCTTCAATTACTCAAAGAAGGAGCCATTTCAGTTAACTCAAGTGAATGAAAGAGTTTTGGAATC TGCTGTGGGTCCTTCCCTGTTGACCATTTGGTAACTTATAATCTGACAAAAACTCTTGAGCTGCAACAGGCCTTGCCAGAGGGCTCAGGA TGGGAAAGGAAGAAGGGGATAGGAAAAGAAGAGGTAATTTTACATTTCCCCTTTAAAGTAAATTTTAGCCAACTCATCATTCTGAAATGT CCCTATAAAGAATGAGTCGAACTAGACCAGAAGCCAGCCTACTCCTTCTTACATAGCTTCTCCAACAGGGGTAGCAATGACCTGTCCACT TCAAACACAGATAAGGCCTGCCATCCTCATTGGTTAAAGGCACACGTGAGACTTTCAGTGGGCTCTGCTGAGAAGGAAGGCAGCCCAGGA GTCAGGTATGCAGGCATTGCATTGTCAGTGTCTGCTCTCAGAGTTTACACATTCAATTGCTTCCAAGGGTGAATCTCCTGCTCTGTGAAT GCTATCAGACCCCAAAGGCCAACCTTGGGCTGGGTCTATGTACGTTCTTCCGAAGCACTGATGATCAAAATTGAAGACACATTCAGAGGT TTGATTGGTTGAGATTAACTGGTGTGGTGGTTGGTGTATGTATGTTTTATTTTTATGTCTTTGTATGTAGTTCTACATAATGCAAATTGT >In-frame_PPFIA1_ENST00000389547_chr11_70172924_+_SLC39A11_ENST00000255559_chr17_71027853_-_3624nt GCTCCTCCTCCGCTCCGCCAGTGTCCGGCCGCGGGCCGGCCTTAGTGACTGGGGCGGCGGGCCCCGGGGCCGCGGCGTGGGGCGGGCAGG CGGACGCCGGCCGCGGGCTGCTTTCGTCGGCTCCCAAGCTCTCCCGGAGCGAGCAGCCGCCCGCGAGCCGCCGCGGAGCCTCCTCGCCCG CTCCCGCCGGCGAGCAAGATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAGGTGGAGGCCATGGTTCC GGCTCCCCTTCACAGCCAGATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACCGCCTTCTTGATACACTG AGAGAGACTCAAGAAACGCTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGCAGAGACAGCTCAACACG GCACTTCCACAGGAGTTCGCAGCACTTACTAAAGAACTCAATGTATGCAGGGAACAGCTCCTTGAAAGGGAAGAAGAAATTGCTGAACTG AAAGCAGAAAGGAATAACACCAGGCTGCTGTTAGAGCATTTGGAATGCCTTGTCTCCAGGCATGAGCGGTCTCTTAGGATGACCGTGGTG AAGAGACAAGCGCAGTCTCCAGCAGGCGTGTCCAGCGAAGTGGAAGTGCTGAAAGCACTGAAGTCCTTATTTGAACACCACAAAGCTCTG GATGAAAAGGTGAGAGAGCGATTACGAGTAGCACTTGAAAGATGTAGTTTGTTAGAAGAGGAATTAGGTGCCACACACAAAGAGCTAATG ATTCTTAAAGAACAGAATAATCAGAAAAAAACTCTAACAGATGGAGTGCTGGACATAAACCATGAACAAGAAAATACACCAAGCACGAGT GGAAAGAGATCTTCTGATGGTTCTTTAAGCCACGAGGAAGACCTTGCTAAAGTAATTGAGCTCCAAGAAATCATAAGTAAGCAGTCAAGG GAACAGAGCCAAATGAAAGAACGCCTGGCTTCCCTTTCCAGTCATGTGACAGAACTGGAAGAGGATCTGGACACGGCTAGAAAAGATCTC ATCAAATCTGAAGAAATGAACACAAAATTGCAACGAGATGTCCGTGAAGTCATGTTGGCAGCTTCCTATTGGTCTCTTCTGGCCCCAGCA GTTGAGATGGCCACGTCCTCTGGGGGCTTCGGTGCCTTTGCCTTCTTCCCTGTGGCTGTTGGCTTCACCCTTGGAGCGGCTTTTGTCTAC TTGGCTGACCTCCTGATGCCTCACTTGGGTGCAGCAGAAGACCCCCAGACGACCCTGGCACTGAACTTCGGCTCTACGTTGATGAAGAAG AAGTCTGATCCTGAGGGTCCCGCGCTGCTCTTCCCTGAGAGTGAACTTTCCATCCGGATAGACAAGAGTGAGAATGGTGAGGCATATCAG AGAAAGAAGGCGGCAGCCACTGGCCTTCCAGAGGGTCCTGCTGTCCCTGTGCCTTCTCGAGGGAATCTGGCACAGCCCGGCGGCAGCAGC TGGAGGAGGATCGCACTGCTCATCTTGGCCATCACTATACACAACGTTCCAGAGGGTCTCGCTGTTGGAGTTGGATTTGGGGCTATAGAA AAGACGGCATCTGCTACCTTTGAGAGTGCCAGGAATTTGGCCATTGGAATCGGGATCCAGAATTTCCCCGAGGGCCTGGCTGTCAGCCTT CCCTTGCGAGGGGCAGGCTTCTCCACCTGGAGAGCTTTCTGGTATGGGCAGCTGAGCGGCATGGTGGAGCCCCTGGCCGGGGTCTTTGGT GCCTTTGCCGTGGTGCTGGCTGAGCCCATCCTGCCCTACGCTCTGGCCTTTGCTGCCGGTGCCATGGTCTACGTGGTCATGGACGACATC ATCCCCGAAGCCCAGATCAGTGGTAATGGGAAACTGGCATCCTGGGCCTCCATCCTGGGATTTGTAGTGATGATGTCACTGGACGTTGGC CTGGGCTAGGGCTGAGACGCTTCGGACCCCGGGAAAGGCCATACGAAGAAACAGCAGTGGTTGGCTTCTATGGGACAACAAGCTTCTTTC TTCACATTAAAACTTTTTTCCTTCCTCTCTTCTTCATCTCATTATCCTGATTGACTCTGATTATAATAGAACCATTTTTACTTTGCTTTG AGGGAGATTTTTGATTTAATGGGGAATTTTAAGGTGTCATGGAAATACAGATTCTTTGTTTTGGCCACTGAATGGACTCTCTCTTCAGTG GGATTATCAAGGAACTTCAGATCAGGGAAATCTCCACTTCGGGACCTTCTATCTGCCTCCCAACTCCTCAAGGTCACCTATAGAAGCGAG CTACCAAAAGACGTCTCCTAAGCATTTTGGTGGCCTAGTGACTCAGGGCAGAGTGGCCAGCACACCTCTCATCCGCCCCTCCTGCTCCAT CACTGCTGAGCCTCTCCCCATCTAGAATGTTGGAACTGGAGCATCATAAAGATAGCAAGCTACCTTCCAAGGCCGAGCCAGCCCAGAGAG GAGCATGTCTTCCTTTACCTCCCCCTAAGGAGATACTACATGGGAGGGGGACACAGAAAAAGGGAAGGAAATTGGCTAGTCTGGCTTTTT TTTTTTTTTTTTTTAAAGGCAAAGATTGACATTATTGAAGGAAAGGGGATGAGGACAACTGTGAACTCACAGTGAGCCCTGTGGAAAGAA GAGACAGACAGAGTGTGGGTTTGTTCGGAGGCCTCTGCTGTCAATGGATTCCAGGAGCAAGGCCATTTGTCGCGCTTTCCAAATTTCTTA GGCATTTATTTTGATAAGTTTATAGCCATCATGTTTCTAAGAGACTTGGAGACACCAGCAAACTGCTAGAACTCAAACTCTTCAATTACT CAAAGAAGGAGCCATTTCAGTTAACTCAAGTGAATGAAAGAGTTTTGGAATCTGCTGTGGGTCCTTCCCTGTTGACCATTTGGTAACTTA TAATCTGACAAAAACTCTTGAGCTGCAACAGGCCTTGCCAGAGGGCTCAGGATGGGAAAGGAAGAAGGGGATAGGAAAAGAAGAGGTAAT TTTACATTTCCCCTTTAAAGTAAATTTTAGCCAACTCATCATTCTGAAATGTCCCTATAAAGAATGAGTCGAACTAGACCAGAAGCCAGC CTACTCCTTCTTACATAGCTTCTCCAACAGGGGTAGCAATGACCTGTCCACTTCAAACACAGATAAGGCCTGCCATCCTCATTGGTTAAA GGCACACGTGAGACTTTCAGTGGGCTCTGCTGAGAAGGAAGGCAGCCCAGGAGTCAGGTATGCAGGCATTGCATTGTCAGTGTCTGCTCT CAGAGTTTACACATTCAATTGCTTCCAAGGGTGAATCTCCTGCTCTGTGAATGCTATCAGACCCCAAAGGCCAACCTTGGGCTGGGTCTA TGTACGTTCTTCCGAAGCACTGATGATCAAAATTGAAGACACATTCAGAGGTTTGATTGGTTGAGATTAACTGGTGTGGTGGTTGGTGTA TGTATGTTTTATTTTTATGTCTTTGTATGTAGTTCTACATAATGCAAATTGTGCTTTCTGATGGACAAGACCTCATAACTGTGATTAATA >In-frame_PPFIA1_ENST00000389547_chr11_70172924_+_SLC39A11_ENST00000542342_chr17_71027853_-_3644nt GCTCCTCCTCCGCTCCGCCAGTGTCCGGCCGCGGGCCGGCCTTAGTGACTGGGGCGGCGGGCCCCGGGGCCGCGGCGTGGGGCGGGCAGG CGGACGCCGGCCGCGGGCTGCTTTCGTCGGCTCCCAAGCTCTCCCGGAGCGAGCAGCCGCCCGCGAGCCGCCGCGGAGCCTCCTCGCCCG CTCCCGCCGGCGAGCAAGATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAGGTGGAGGCCATGGTTCC GGCTCCCCTTCACAGCCAGATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACCGCCTTCTTGATACACTG AGAGAGACTCAAGAAACGCTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGCAGAGACAGCTCAACACG GCACTTCCACAGGAGTTCGCAGCACTTACTAAAGAACTCAATGTATGCAGGGAACAGCTCCTTGAAAGGGAAGAAGAAATTGCTGAACTG AAAGCAGAAAGGAATAACACCAGGCTGCTGTTAGAGCATTTGGAATGCCTTGTCTCCAGGCATGAGCGGTCTCTTAGGATGACCGTGGTG AAGAGACAAGCGCAGTCTCCAGCAGGCGTGTCCAGCGAAGTGGAAGTGCTGAAAGCACTGAAGTCCTTATTTGAACACCACAAAGCTCTG GATGAAAAGGTGAGAGAGCGATTACGAGTAGCACTTGAAAGATGTAGTTTGTTAGAAGAGGAATTAGGTGCCACACACAAAGAGCTAATG ATTCTTAAAGAACAGAATAATCAGAAAAAAACTCTAACAGATGGAGTGCTGGACATAAACCATGAACAAGAAAATACACCAAGCACGAGT GGAAAGAGATCTTCTGATGGTTCTTTAAGCCACGAGGAAGACCTTGCTAAAGTAATTGAGCTCCAAGAAATCATAAGTAAGCAGTCAAGG GAACAGAGCCAAATGAAAGAACGCCTGGCTTCCCTTTCCAGTCATGTGACAGAACTGGAAGAGGATCTGGACACGGCTAGAAAAGATCTC ATCAAATCTGAAGAAATGAACACAAAATTGCAACGAGATGTCCGTGAAGTCATGTTGGCAGCTTCCTATTGGTCTCTTCTGGCCCCAGCA GTTGAGATGGCCACGTCCTCTGGGGGCTTCGGTGCCTTTGCCTTCTTCCCTGTGGCTGTTGGCTTCACCCTTGGAGCGGCTTTTGTCTAC TTGGCTGACCTCCTGATGCCTCACTTGGGTGCAGCAGAAGACCCCCAGACGACCCTGGCACTGAACTTCGGCTCTACGTTGATGAAGAAG AAGTCTGATCCTGAGGGTCCCGCGCTGCTCTTCCCTGAGAGTGAACTTTCCATCCGGATAGGTAGAGCTGGGCTTCTTTCAGACAAGAGT GAGAATGGTGAGGCATATCAGAGAAAGAAGGCGGCAGCCACTGGCCTTCCAGAGGGTCCTGCTGTCCCTGTGCCTTCTCGAGGGAATCTG GCACAGCCCGGCGGCAGCAGCTGGAGGAGGATCGCACTGCTCATCTTGGCCATCACTATACACAACGTTCCAGAGGGTCTCGCTGTTGGA GTTGGATTTGGGGCTATAGAAAAGACGGCATCTGCTACCTTTGAGAGTGCCAGGAATTTGGCCATTGGAATCGGGATCCAGAATTTCCCC GAGGGCCTGGCTGTCAGCCTTCCCTTGCGAGGGGCAGGCTTCTCCACCTGGAGAGCTTTCTGGTATGGGCAGCTGAGCGGCATGGTGGAG CCCCTGGCCGGGGTCTTTGGTGCCTTTGCCGTGGTGCTGGCTGAGCCCATCCTGCCCTACGCTCTGGCCTTTGCTGCCGGTGCCATGGTC TACGTGGTCATGGACGACATCATCCCCGAAGCCCAGATCAGTGGTAATGGGAAACTGGCATCCTGGGCCTCCATCCTGGGATTTGTAGTG ATGATGTCACTGGACGTTGGCCTGGGCTAGGGCTGAGACGCTTCGGACCCCGGGAAAGGCCATACGAAGAAACAGCAGTGGTTGGCTTCT ATGGGACAACAAGCTTCTTTCTTCACATTAAAACTTTTTTCCTTCCTCTCTTCTTCATCTCATTATCCTGATTGACTCTGATTATAATAG AACCATTTTTACTTTGCTTTGAGGGAGATTTTTGATTTAATGGGGAATTTTAAGGTGTCATGGAAATACAGATTCTTTGTTTTGGCCACT GAATGGACTCTCTCTTCAGTGGGATTATCAAGGAACTTCAGATCAGGGAAATCTCCACTTCGGGACCTTCTATCTGCCTCCCAACTCCTC AAGGTCACCTATAGAAGCGAGCTACCAAAAGACGTCTCCTAAGCATTTTGGTGGCCTAGTGACTCAGGGCAGAGTGGCCAGCACACCTCT CATCCGCCCCTCCTGCTCCATCACTGCTGAGCCTCTCCCCATCTAGAATGTTGGAACTGGAGCATCATAAAGATAGCAAGCTACCTTCCA AGGCCGAGCCAGCCCAGAGAGGAGCATGTCTTCCTTTACCTCCCCCTAAGGAGATACTACATGGGAGGGGGACACAGAAAAAGGGAAGGA AATTGGCTAGTCTGGCTTTTTTTTTTTTTTTTTTTAAAGGCAAAGATTGACATTATTGAAGGAAAGGGGATGAGGACAACTGTGAACTCA CAGTGAGCCCTGTGGAAAGAAGAGACAGACAGAGTGTGGGTTTGTTCGGAGGCCTCTGCTGTCAATGGATTCCAGGAGCAAGGCCATTTG TCGCGCTTTCCAAATTTCTTAGGCATTTATTTTGATAAGTTTATAGCCATCATGTTTCTAAGAGACTTGGAGACACCAGCAAACTGCTAG AACTCAAACTCTTCAATTACTCAAAGAAGGAGCCATTTCAGTTAACTCAAGTGAATGAAAGAGTTTTGGAATCTGCTGTGGGTCCTTCCC TGTTGACCATTTGGTAACTTATAATCTGACAAAAACTCTTGAGCTGCAACAGGCCTTGCCAGAGGGCTCAGGATGGGAAAGGAAGAAGGG GATAGGAAAAGAAGAGGTAATTTTACATTTCCCCTTTAAAGTAAATTTTAGCCAACTCATCATTCTGAAATGTCCCTATAAAGAATGAGT CGAACTAGACCAGAAGCCAGCCTACTCCTTCTTACATAGCTTCTCCAACAGGGGTAGCAATGACCTGTCCACTTCAAACACAGATAAGGC CTGCCATCCTCATTGGTTAAAGGCACACGTGAGACTTTCAGTGGGCTCTGCTGAGAAGGAAGGCAGCCCAGGAGTCAGGTATGCAGGCAT TGCATTGTCAGTGTCTGCTCTCAGAGTTTACACATTCAATTGCTTCCAAGGGTGAATCTCCTGCTCTGTGAATGCTATCAGACCCCAAAG GCCAACCTTGGGCTGGGTCTATGTACGTTCTTCCGAAGCACTGATGATCAAAATTGAAGACACATTCAGAGGTTTGATTGGTTGAGATTA ACTGGTGTGGTGGTTGGTGTATGTATGTTTTATTTTTATGTCTTTGTATGTAGTTCTACATAATGCAAATTGTGCTTTCTGATGGACAAG |
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FusionGenePPI for PPFIA1_SLC39A11 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| PPFIA1 | GIT1, ERC2, PPP2R5D, TNNT1, MBIP, GRIP2, PTPRF, PTPRD, PTPRS, NCOA2, PPP2CA, PPP2R1A, PPFIA1, PPFIA2, ING4, PPP2CB, CUL2, AGTPBP1, CEP70, AMOT, LATS2, YWHAB, IKBKG, PSMC4, PSMD1, PSMD13, PSMD8, SPTAN1, DROSHA, NDN, AURKB, CDKN1A, CCNH, DTNB, FAM161A, TXLNA, BRCA1, GPS2, C16orf70, CYP4X1, NTRK1, OSBP, PPFIA3, PPFIBP1, PPFIBP2, CAGE1, TUBG1, XRCC1, GBA2, CDC5L, NF2, IL17RE, LLGL2, SERPINB2, STX11, EXOC8, TTC9B, CCDC120, TRIM25 | SLC39A11 | ELAVL1, EGFR, CD33, TMEM51, CD274, PVRIG, SLAMF1, TMEFF1, WBP1, SPN, SCN2B, PON2, IZUMO1, EPHA1, FAM174A, SIGLEC12, GAPDHS, GALNT16, LRRC4C, A2ML1, ST3GAL1, HAL, PCDHB16, CLEC2D, VASN, PMEL, NTRK3 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for PPFIA1_SLC39A11 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for PPFIA1_SLC39A11 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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