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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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Fusion gene ID: 28139

FusionGeneSummary for PPFIA1_MARK2

check button Fusion gene summary
Fusion gene informationFusion gene name: PPFIA1_MARK2
Fusion gene ID: 28139
HgeneTgene
Gene symbol

PPFIA1

MARK2

Gene ID

8500

2011

Gene namePTPRF interacting protein alpha 1microtubule affinity regulating kinase 2
SynonymsLIP.1|LIP1|LIPRINEMK-1|EMK1|PAR-1|Par-1b|Par1b
Cytomap

11q13.3

11q13.1

Type of geneprotein-codingprotein-coding
Descriptionliprin-alpha-1LAR-interacting protein 1LIP-1Liprin-alpha1protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1serine/threonine-protein kinase MARK2ELKL motif kinase 1MAP/microtubule affinity-regulating kinase 2PAR1 homolog bSer/Thr protein kinase PAR-1Bserine/threonine protein kinase EMKtesticular tissue protein Li 117
Modification date2018052220180523
UniProtAcc

Q13136

Q7KZI7

Ensembl transtripts involved in fusion geneENST00000253925, ENST00000389547, 
ENST00000530548, 		ENST00000377809, 
ENST00000402010, ENST00000413835, 
ENST00000377810, ENST00000315032, 
ENST00000508192, ENST00000361128, 
ENST00000350490, ENST00000502399, 
ENST00000509502, ENST00000513765, 
ENST00000408948, ENST00000425897, 
Fusion gene scores* DoF score36 X 13 X 14=65524 X 3 X 3=36
# samples 415
** MAII scorelog2(41/6552*10)=-3.99823954213556
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/36*10)=0.473931188332412
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: PPFIA1 [Title/Abstract] AND MARK2 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationKinase involved fusion gene, inframe and retained kinase domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneMARK2

GO:0006468

protein phosphorylation

14976552

TgeneMARK2

GO:0010976

positive regulation of neuron projection development

12429843

TgeneMARK2

GO:0018105

peptidyl-serine phosphorylation

10542369

TgeneMARK2

GO:0030010

establishment of cell polarity

12429843

TgeneMARK2

GO:0035556

intracellular signal transduction

14976552

TgeneMARK2

GO:0045197

establishment or maintenance of epithelial cell apical/basal polarity

15324659

TgeneMARK2

GO:0070507

regulation of microtubule cytoskeleton organization

10542369


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVBRCATCGA-A2-A1G4-01APPFIA1chr11

70118542

+MARK2chr11

63662631

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000253925ENST00000377809PPFIA1chr11

70118542

+MARK2chr11

63662631

+
In-frameENST00000253925ENST00000402010PPFIA1chr11

70118542

+MARK2chr11

63662631

+
In-frameENST00000253925ENST00000413835PPFIA1chr11

70118542

+MARK2chr11

63662631

+
5CDS-5UTRENST00000253925ENST00000377810PPFIA1chr11

70118542

+MARK2chr11

63662631

+
5CDS-5UTRENST00000253925ENST00000315032PPFIA1chr11

70118542

+MARK2chr11

63662631

+
5CDS-5UTRENST00000253925ENST00000508192PPFIA1chr11

70118542

+MARK2chr11

63662631

+
5CDS-5UTRENST00000253925ENST00000361128PPFIA1chr11

70118542

+MARK2chr11

63662631

+
5CDS-5UTRENST00000253925ENST00000350490PPFIA1chr11

70118542

+MARK2chr11

63662631

+
5CDS-5UTRENST00000253925ENST00000502399PPFIA1chr11

70118542

+MARK2chr11

63662631

+
5CDS-5UTRENST00000253925ENST00000509502PPFIA1chr11

70118542

+MARK2chr11

63662631

+
5CDS-5UTRENST00000253925ENST00000513765PPFIA1chr11

70118542

+MARK2chr11

63662631

+
5CDS-intronENST00000253925ENST00000408948PPFIA1chr11

70118542

+MARK2chr11

63662631

+
5CDS-intronENST00000253925ENST00000425897PPFIA1chr11

70118542

+MARK2chr11

63662631

+
In-frameENST00000389547ENST00000377809PPFIA1chr11

70118542

+MARK2chr11

63662631

+
In-frameENST00000389547ENST00000402010PPFIA1chr11

70118542

+MARK2chr11

63662631

+
In-frameENST00000389547ENST00000413835PPFIA1chr11

70118542

+MARK2chr11

63662631

+
5CDS-5UTRENST00000389547ENST00000377810PPFIA1chr11

70118542

+MARK2chr11

63662631

+
5CDS-5UTRENST00000389547ENST00000315032PPFIA1chr11

70118542

+MARK2chr11

63662631

+
5CDS-5UTRENST00000389547ENST00000508192PPFIA1chr11

70118542

+MARK2chr11

63662631

+
5CDS-5UTRENST00000389547ENST00000361128PPFIA1chr11

70118542

+MARK2chr11

63662631

+
5CDS-5UTRENST00000389547ENST00000350490PPFIA1chr11

70118542

+MARK2chr11

63662631

+
5CDS-5UTRENST00000389547ENST00000502399PPFIA1chr11

70118542

+MARK2chr11

63662631

+
5CDS-5UTRENST00000389547ENST00000509502PPFIA1chr11

70118542

+MARK2chr11

63662631

+
5CDS-5UTRENST00000389547ENST00000513765PPFIA1chr11

70118542

+MARK2chr11

63662631

+
5CDS-intronENST00000389547ENST00000408948PPFIA1chr11

70118542

+MARK2chr11

63662631

+
5CDS-intronENST00000389547ENST00000425897PPFIA1chr11

70118542

+MARK2chr11

63662631

+
intron-3CDSENST00000530548ENST00000377809PPFIA1chr11

70118542

+MARK2chr11

63662631

+
intron-3CDSENST00000530548ENST00000402010PPFIA1chr11

70118542

+MARK2chr11

63662631

+
intron-3CDSENST00000530548ENST00000413835PPFIA1chr11

70118542

+MARK2chr11

63662631

+
intron-5UTRENST00000530548ENST00000377810PPFIA1chr11

70118542

+MARK2chr11

63662631

+
intron-5UTRENST00000530548ENST00000315032PPFIA1chr11

70118542

+MARK2chr11

63662631

+
intron-5UTRENST00000530548ENST00000508192PPFIA1chr11

70118542

+MARK2chr11

63662631

+
intron-5UTRENST00000530548ENST00000361128PPFIA1chr11

70118542

+MARK2chr11

63662631

+
intron-5UTRENST00000530548ENST00000350490PPFIA1chr11

70118542

+MARK2chr11

63662631

+
intron-5UTRENST00000530548ENST00000502399PPFIA1chr11

70118542

+MARK2chr11

63662631

+
intron-5UTRENST00000530548ENST00000509502PPFIA1chr11

70118542

+MARK2chr11

63662631

+
intron-5UTRENST00000530548ENST00000513765PPFIA1chr11

70118542

+MARK2chr11

63662631

+
intron-intronENST00000530548ENST00000408948PPFIA1chr11

70118542

+MARK2chr11

63662631

+
intron-intronENST00000530548ENST00000425897PPFIA1chr11

70118542

+MARK2chr11

63662631

+

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FusionProtFeatures for PPFIA1_MARK2


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
PPFIA1

Q13136

MARK2

Q7KZI7

May regulate the disassembly of focal adhesions. Maylocalize receptor-like tyrosine phosphatases type 2A at specificsites on the plasma membrane, possibly regulating theirinteraction with the extracellular environment and theirassociation with substrates. {ECO:0000269|PubMed:7796809}. Serine/threonine-protein kinase (PubMed:23666762).Involved in cell polarity and microtubule dynamics regulation.Phosphorylates CRTC2/TORC2, DCX, HDAC7, KIF13B, MAP2, MAP4 andRAB11FIP2. Phosphorylates the microtubule-associated proteinMAPT/TAU (PubMed:23666762). Plays a key role in cell polarity byphosphorylating the microtubule-associated proteins MAP2, MAP4 andMAPT/TAU at KXGS motifs, causing detachment from microtubules, andtheir disassembly. Regulates epithelial cell polarity byphosphorylating RAB11FIP2. Involved in the regulation of neuronalmigration through its dual activities in regulating cellularpolarity and microtubule dynamics, possibly by phosphorylating andregulating DCX. Regulates axogenesis by phosphorylating KIF13B,promoting interaction between KIF13B and 14-3-3 and inhibitingmicrotubule-dependent accumulation of KIF13B. Also required forneurite outgrowth and establishment of neuronal polarity.Regulates localization and activity of some histone deacetylasesby mediating phosphorylation of HDAC7, promoting subsequentinteraction between HDAC7 and 14-3-3 and export from the nucleus.Also acts as a positive regulator of the Wnt signaling pathway,probably by mediating phosphorylation of dishevelled proteins(DVL1, DVL2 and/or DVL3). Modulates the developmental decision tobuild a columnar versus a hepatic epithelial cell apparently bypromoting a switch from a direct to a transcytotic mode of apicalprotein delivery. Essential for the asymmetric development ofmembrane domains of polarized epithelial cells.{ECO:0000269|PubMed:11433294, ECO:0000269|PubMed:12429843,ECO:0000269|PubMed:14976552, ECO:0000269|PubMed:15158914,ECO:0000269|PubMed:15324659, ECO:0000269|PubMed:15365179,ECO:0000269|PubMed:16775013, ECO:0000269|PubMed:16980613,ECO:0000269|PubMed:18626018, ECO:0000269|PubMed:20194617,ECO:0000269|PubMed:23666762}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePPFIA1chr11:70118542chr11:63662631ENST00000253925+22817_25881597Compositional biasNote=Poly-Gly
HgenePPFIA1chr11:70118542chr11:63662631ENST00000389547+22617_25881186Compositional biasNote=Poly-Gly
TgeneMARK2chr11:70118542chr11:63662631ENST00000315032+018323_36218780DomainUBA
TgeneMARK2chr11:70118542chr11:63662631ENST00000315032+01853_30418780DomainProtein kinase
TgeneMARK2chr11:70118542chr11:63662631ENST00000315032+018739_78818780DomainKA1
TgeneMARK2chr11:70118542chr11:63662631ENST00000350490+016323_36218710DomainUBA
TgeneMARK2chr11:70118542chr11:63662631ENST00000350490+01653_30418710DomainProtein kinase
TgeneMARK2chr11:70118542chr11:63662631ENST00000350490+016739_78818710DomainKA1
TgeneMARK2chr11:70118542chr11:63662631ENST00000361128+017323_36218720DomainUBA
TgeneMARK2chr11:70118542chr11:63662631ENST00000361128+01753_30418720DomainProtein kinase
TgeneMARK2chr11:70118542chr11:63662631ENST00000361128+017739_78818720DomainKA1
TgeneMARK2chr11:70118542chr11:63662631ENST00000377809+018323_36218774DomainUBA
TgeneMARK2chr11:70118542chr11:63662631ENST00000377809+01853_30418774DomainProtein kinase
TgeneMARK2chr11:70118542chr11:63662631ENST00000377809+018739_78818774DomainKA1
TgeneMARK2chr11:70118542chr11:63662631ENST00000377810+017323_362-15692DomainUBA
TgeneMARK2chr11:70118542chr11:63662631ENST00000377810+01753_304-15692DomainProtein kinase
TgeneMARK2chr11:70118542chr11:63662631ENST00000377810+017739_788-15692DomainKA1
TgeneMARK2chr11:70118542chr11:63662631ENST00000402010+019323_36218789DomainUBA
TgeneMARK2chr11:70118542chr11:63662631ENST00000402010+01953_30418789DomainProtein kinase
TgeneMARK2chr11:70118542chr11:63662631ENST00000402010+019739_78818789DomainKA1
TgeneMARK2chr11:70118542chr11:63662631ENST00000408948+016323_362-6692DomainUBA
TgeneMARK2chr11:70118542chr11:63662631ENST00000408948+01653_304-6692DomainProtein kinase
TgeneMARK2chr11:70118542chr11:63662631ENST00000408948+016739_788-6692DomainKA1
TgeneMARK2chr11:70118542chr11:63662631ENST00000413835+018323_36218735DomainUBA
TgeneMARK2chr11:70118542chr11:63662631ENST00000413835+01853_30418735DomainProtein kinase
TgeneMARK2chr11:70118542chr11:63662631ENST00000413835+018739_78818735DomainKA1
TgeneMARK2chr11:70118542chr11:63662631ENST00000508192+017323_36218725DomainUBA
TgeneMARK2chr11:70118542chr11:63662631ENST00000508192+01753_30418725DomainProtein kinase
TgeneMARK2chr11:70118542chr11:63662631ENST00000508192+017739_78818725DomainKA1
TgeneMARK2chr11:70118542chr11:63662631ENST00000509502+018323_362-15746DomainUBA
TgeneMARK2chr11:70118542chr11:63662631ENST00000509502+01853_304-15746DomainProtein kinase
TgeneMARK2chr11:70118542chr11:63662631ENST00000509502+018739_788-15746DomainKA1
TgeneMARK2chr11:70118542chr11:63662631ENST00000513765+-118323_36245756DomainUBA
TgeneMARK2chr11:70118542chr11:63662631ENST00000513765+-11853_30445756DomainProtein kinase
TgeneMARK2chr11:70118542chr11:63662631ENST00000513765+-118739_78845756DomainKA1
TgeneMARK2chr11:70118542chr11:63662631ENST00000315032+01859_6718780Nucleotide bindingATP
TgeneMARK2chr11:70118542chr11:63662631ENST00000350490+01659_6718710Nucleotide bindingATP
TgeneMARK2chr11:70118542chr11:63662631ENST00000361128+01759_6718720Nucleotide bindingATP
TgeneMARK2chr11:70118542chr11:63662631ENST00000377809+01859_6718774Nucleotide bindingATP
TgeneMARK2chr11:70118542chr11:63662631ENST00000377810+01759_67-15692Nucleotide bindingATP
TgeneMARK2chr11:70118542chr11:63662631ENST00000402010+01959_6718789Nucleotide bindingATP
TgeneMARK2chr11:70118542chr11:63662631ENST00000408948+01659_67-6692Nucleotide bindingATP
TgeneMARK2chr11:70118542chr11:63662631ENST00000413835+01859_6718735Nucleotide bindingATP
TgeneMARK2chr11:70118542chr11:63662631ENST00000508192+01759_6718725Nucleotide bindingATP
TgeneMARK2chr11:70118542chr11:63662631ENST00000509502+01859_67-15746Nucleotide bindingATP
TgeneMARK2chr11:70118542chr11:63662631ENST00000513765+-11859_6745756Nucleotide bindingATP

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePPFIA1chr11:70118542chr11:63662631ENST00000253925+2281021_1050881597Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:63662631ENST00000253925+228176_214881597Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:63662631ENST00000253925+228249_521881597Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:63662631ENST00000253925+22834_141881597Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:63662631ENST00000253925+228623_669881597Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:63662631ENST00000253925+228847_871881597Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:63662631ENST00000389547+2261021_1050881186Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:63662631ENST00000389547+226176_214881186Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:63662631ENST00000389547+226249_521881186Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:63662631ENST00000389547+22634_141881186Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:63662631ENST00000389547+226623_669881186Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:63662631ENST00000389547+226847_871881186Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:63662631ENST00000253925+2281051_1120881597DomainSAM 3
HgenePPFIA1chr11:70118542chr11:63662631ENST00000253925+228878_944881597DomainSAM 1
HgenePPFIA1chr11:70118542chr11:63662631ENST00000253925+228963_1027881597DomainSAM 2
HgenePPFIA1chr11:70118542chr11:63662631ENST00000389547+2261051_1120881186DomainSAM 3
HgenePPFIA1chr11:70118542chr11:63662631ENST00000389547+226878_944881186DomainSAM 1
HgenePPFIA1chr11:70118542chr11:63662631ENST00000389547+226963_1027881186DomainSAM 2


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FusionGeneSequence for PPFIA1_MARK2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_PPFIA1_ENST00000253925_chr11_70118542_+_MARK2_ENST00000377809_chr11_63662631_+_844aa
MMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLMVSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQPT
LGHLDSKPSSKSNMIRGRNSATSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHP
NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEF
TFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPS
KRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLVGQRYNEVMATYLLLGYKSSELEGDTITLKPRPS
ADLTNSSAPSPSHKVQRSVSANPKQRRFSDQAAGPAIPTSNSYSKKTQSNNAENKRPEEDRESGRKASSTAKVPASPLPGLERKKTTPTP
STNSVLSTSTNRSRNSPLLERASLGQASIQNGKDSLTMPGSRASTASASAAVSAARPRQHQKSMSASVHPNKASGLPPTESNCEVPRPST
APQRVPVASPSAHNISSSGGAPDRTNFPRGVSSRSTFHAGQLRQVRDQQNLPYGVTPASPSGHSQGRRGASGSIFSKFTSKFVRRNLSFR
FARRPHVVGSGGNDKEKEEFREAKPRSLRFTWSMKTTSSMEPNEMMREIRKVLDANSCQSELHEKYMLLCMHGTPGHEDFVQWEMEVCKL

>In-frame_PPFIA1_ENST00000253925_chr11_70118542_+_MARK2_ENST00000402010_chr11_63662631_+_859aa
MMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLMVSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQPT
LGHLDSKPSSKSNMIRGRNSATSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHP
NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEF
TFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPS
KRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLVGQRYNEVMATYLLLGYKSSELEGDTITLKPRPS
ADLTNSSAPSPSHKVQRSVSANPKQRRFSDQAAGPAIPTSNSYSKKTQSNNAENKRPEEDRESGRKASSTAKVPASPLPGLERKKTTPTP
STNSVLSTSTNRSRNSPLLERASLGQASIQNGKDSLTMPGSRASTASASAAVSAARPRQHQKSMSASVHPNKASGLPPTESNCEVPRPST
APQRVPVASPSAHNISSSGGAPDRTNFPRGVSSRSTFHAGQLRQVRDQQNLPYGVTPASPSGHSQGRRGASGSIFSKFTSKFVRRNLSFR
FARRNLNEPESKDRVETLRPHVVGSGGNDKEKEEFREAKPRSLRFTWSMKTTSSMEPNEMMREIRKVLDANSCQSELHEKYMLLCMHGTP

>In-frame_PPFIA1_ENST00000253925_chr11_70118542_+_MARK2_ENST00000413835_chr11_63662631_+_805aa
MMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLMVSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQPT
LGHLDSKPSSKSNMIRGRNSATSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHP
NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEF
TFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPS
KRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLVGQRYNEVMATYLLLGYKSSELEGDTITLKPRPS
ADLTNSSAPSPSHKVQRSVSANPKQRRFSDQAAGPAIPTSNSYSKKTQSNNAENKRPEEDRESGRKASSTAKVPASPLPGLERKKTTPTP
STNSVLSTSTNRSRNSPLLERASLGQASIQNGKDSTAPQRVPVASPSAHNISSSGGAPDRTNFPRGVSSRSTFHAGQLRQVRDQQNLPYG
VTPASPSGHSQGRRGASGSIFSKFTSKFVRRNLSFRFARRNLNEPESKDRVETLRPHVVGSGGNDKEKEEFREAKPRSLRFTWSMKTTSS

>In-frame_PPFIA1_ENST00000389547_chr11_70118542_+_MARK2_ENST00000377809_chr11_63662631_+_844aa
MMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLMVSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQPT
LGHLDSKPSSKSNMIRGRNSATSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHP
NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEF
TFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPS
KRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLVGQRYNEVMATYLLLGYKSSELEGDTITLKPRPS
ADLTNSSAPSPSHKVQRSVSANPKQRRFSDQAAGPAIPTSNSYSKKTQSNNAENKRPEEDRESGRKASSTAKVPASPLPGLERKKTTPTP
STNSVLSTSTNRSRNSPLLERASLGQASIQNGKDSLTMPGSRASTASASAAVSAARPRQHQKSMSASVHPNKASGLPPTESNCEVPRPST
APQRVPVASPSAHNISSSGGAPDRTNFPRGVSSRSTFHAGQLRQVRDQQNLPYGVTPASPSGHSQGRRGASGSIFSKFTSKFVRRNLSFR
FARRPHVVGSGGNDKEKEEFREAKPRSLRFTWSMKTTSSMEPNEMMREIRKVLDANSCQSELHEKYMLLCMHGTPGHEDFVQWEMEVCKL

>In-frame_PPFIA1_ENST00000389547_chr11_70118542_+_MARK2_ENST00000402010_chr11_63662631_+_859aa
MMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLMVSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQPT
LGHLDSKPSSKSNMIRGRNSATSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHP
NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEF
TFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPS
KRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLVGQRYNEVMATYLLLGYKSSELEGDTITLKPRPS
ADLTNSSAPSPSHKVQRSVSANPKQRRFSDQAAGPAIPTSNSYSKKTQSNNAENKRPEEDRESGRKASSTAKVPASPLPGLERKKTTPTP
STNSVLSTSTNRSRNSPLLERASLGQASIQNGKDSLTMPGSRASTASASAAVSAARPRQHQKSMSASVHPNKASGLPPTESNCEVPRPST
APQRVPVASPSAHNISSSGGAPDRTNFPRGVSSRSTFHAGQLRQVRDQQNLPYGVTPASPSGHSQGRRGASGSIFSKFTSKFVRRNLSFR
FARRNLNEPESKDRVETLRPHVVGSGGNDKEKEEFREAKPRSLRFTWSMKTTSSMEPNEMMREIRKVLDANSCQSELHEKYMLLCMHGTP

>In-frame_PPFIA1_ENST00000389547_chr11_70118542_+_MARK2_ENST00000413835_chr11_63662631_+_805aa
MMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLMVSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQPT
LGHLDSKPSSKSNMIRGRNSATSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHP
NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEF
TFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPS
KRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLVGQRYNEVMATYLLLGYKSSELEGDTITLKPRPS
ADLTNSSAPSPSHKVQRSVSANPKQRRFSDQAAGPAIPTSNSYSKKTQSNNAENKRPEEDRESGRKASSTAKVPASPLPGLERKKTTPTP
STNSVLSTSTNRSRNSPLLERASLGQASIQNGKDSTAPQRVPVASPSAHNISSSGGAPDRTNFPRGVSSRSTFHAGQLRQVRDQQNLPYG
VTPASPSGHSQGRRGASGSIFSKFTSKFVRRNLSFRFARRNLNEPESKDRVETLRPHVVGSGGNDKEKEEFREAKPRSLRFTWSMKTTSS


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_PPFIA1_ENST00000253925_chr11_70118542_+_MARK2_ENST00000377809_chr11_63662631_+_2532nt
ATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAGGTGGAGGCCATGGTTCCGGCTCCCCTTCACAGCCA
GATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACCGCCTTCTTGATACACTGAGAGAGACTCAAGAAACG
CTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGCAGAGACAGCTCAACACGGCACTTCCACAGCCCACC
TTGGGACACCTTGACTCCAAGCCCAGCAGTAAGTCCAACATGATTCGGGGCCGCAACTCAGCCACCTCTGCTGATGAGCAGCCCCACATT
GGAAACTACCGGCTCCTCAAGACCATTGGCAAGGGTAATTTTGCCAAGGTGAAGTTGGCCCGACACATCCTGACTGGGAAAGAGGTAGCT
GTGAAGATCATTGACAAGACTCAACTGAACTCCTCCAGCCTCCAGAAACTATTCCGCGAAGTAAGAATAATGAAGGTTTTGAATCATCCC
AACATAGTTAAATTATTTGAAGTGATTGAGACTGAGAAAACGCTCTACCTTGTCATGGAGTACGCTAGTGGCGGAGAGGTATTTGATTAC
CTAGTGGCTCATGGCAGGATGAAAGAAAAAGAGGCTCGAGCCAAATTCCGCCAGATAGTGTCTGCTGTGCAGTACTGTCACCAGAAGTTT
ATTGTCCATAGAGACTTAAAGGCAGAAAACCTGCTCTTGGATGCTGATATGAACATCAAGATTGCAGACTTTGGCTTCAGCAATGAATTC
ACCTTTGGGAACAAGCTGGACACCTTCTGTGGCAGTCCCCCTTATGCTGCCCCAGAACTCTTCCAGGGCAAAAAATATGATGGACCCGAG
GTGGATGTGTGGAGCCTAGGAGTTATCCTCTATACACTGGTCAGCGGATCCCTGCCTTTTGATGGACAGAACCTCAAGGAGCTGCGGGAA
CGGGTACTGAGGGGAAAATACCGTATTCCATTCTACATGTCCACGGACTGTGAAAACCTGCTTAAGAAATTTCTCATTCTTAATCCCAGC
AAGAGAGGCACTTTAGAGCAAATCATGAAAGATCGATGGATGAATGTGGGTCACGAAGATGATGAACTAAAGCCTTACGTGGAGCCACTC
CCTGACTACAAGGACCCCCGGCGGACAGAGCTGATGGTGTCCATGGGTTATACACGGGAAGAGATCCAGGACTCGCTGGTGGGCCAGAGA
TACAACGAGGTGATGGCCACCTATCTGCTCCTGGGCTACAAGAGCTCCGAGCTGGAAGGCGACACCATCACCCTGAAACCCCGGCCTTCA
GCTGATCTGACCAATAGCAGCGCCCCATCCCCATCCCACAAGGTACAGCGCAGCGTGTCGGCCAATCCCAAGCAGCGGCGCTTCAGCGAC
CAGGCAGCTGGTCCTGCCATTCCCACCTCTAATTCTTACTCTAAGAAGACTCAGAGTAACAACGCAGAAAATAAGCGGCCTGAGGAGGAC
CGGGAGTCAGGGCGGAAAGCCAGCAGCACAGCCAAGGTGCCTGCCAGCCCCCTGCCCGGTCTGGAGAGGAAGAAGACCACCCCAACCCCC
TCCACGAACAGCGTCCTCTCCACCAGCACAAATCGAAGCAGGAATTCCCCACTTTTGGAGCGGGCCAGCCTCGGCCAGGCCTCCATCCAG
AATGGCAAAGACAGCCTAACCATGCCAGGGTCCCGGGCCTCCACGGCTTCTGCTTCTGCCGCAGTCTCTGCGGCCCGGCCCCGCCAGCAC
CAGAAATCCATGTCGGCCTCCGTGCACCCCAACAAGGCCTCTGGGCTGCCCCCCACGGAGAGTAACTGTGAGGTGCCGCGGCCCAGCACA
GCCCCCCAGCGTGTCCCTGTTGCCTCCCCATCCGCCCACAACATCAGCAGCAGTGGTGGAGCCCCAGACCGAACTAACTTCCCCCGGGGT
GTGTCCAGCCGAAGCACCTTCCATGCTGGGCAGCTCCGACAGGTGCGGGACCAGCAGAATTTGCCCTACGGTGTGACCCCAGCCTCTCCC
TCTGGCCACAGCCAGGGCCGGCGGGGGGCCTCTGGGAGCATCTTCAGCAAGTTCACCTCCAAGTTTGTACGCAGAAATCTGTCTTTCAGG
TTTGCCAGAAGACCTCACGTGGTGGGCAGTGGCGGCAACGACAAAGAAAAGGAAGAATTTCGGGAGGCCAAGCCCCGCTCCCTCCGCTTC
ACGTGGAGTATGAAGACCACGAGCTCCATGGAGCCCAACGAGATGATGCGGGAGATCCGCAAGGTGCTGGACGCGAACAGCTGCCAGAGC
GAGCTGCATGAGAAGTACATGCTGCTGTGCATGCACGGCACGCCGGGCCACGAGGACTTCGTGCAGTGGGAGATGGAGGTGTGCAAACTG
CCGCGGCTCTCTCTCAACGGGGTTCGATTTAAGCGGATATCGGGCACCTCCATGGCCTTCAAAAACATTGCCTCCAAAATAGCCAACGAG

>In-frame_PPFIA1_ENST00000253925_chr11_70118542_+_MARK2_ENST00000402010_chr11_63662631_+_2577nt
ATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAGGTGGAGGCCATGGTTCCGGCTCCCCTTCACAGCCA
GATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACCGCCTTCTTGATACACTGAGAGAGACTCAAGAAACG
CTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGCAGAGACAGCTCAACACGGCACTTCCACAGCCCACC
TTGGGACACCTTGACTCCAAGCCCAGCAGTAAGTCCAACATGATTCGGGGCCGCAACTCAGCCACCTCTGCTGATGAGCAGCCCCACATT
GGAAACTACCGGCTCCTCAAGACCATTGGCAAGGGTAATTTTGCCAAGGTGAAGTTGGCCCGACACATCCTGACTGGGAAAGAGGTAGCT
GTGAAGATCATTGACAAGACTCAACTGAACTCCTCCAGCCTCCAGAAACTATTCCGCGAAGTAAGAATAATGAAGGTTTTGAATCATCCC
AACATAGTTAAATTATTTGAAGTGATTGAGACTGAGAAAACGCTCTACCTTGTCATGGAGTACGCTAGTGGCGGAGAGGTATTTGATTAC
CTAGTGGCTCATGGCAGGATGAAAGAAAAAGAGGCTCGAGCCAAATTCCGCCAGATAGTGTCTGCTGTGCAGTACTGTCACCAGAAGTTT
ATTGTCCATAGAGACTTAAAGGCAGAAAACCTGCTCTTGGATGCTGATATGAACATCAAGATTGCAGACTTTGGCTTCAGCAATGAATTC
ACCTTTGGGAACAAGCTGGACACCTTCTGTGGCAGTCCCCCTTATGCTGCCCCAGAACTCTTCCAGGGCAAAAAATATGATGGACCCGAG
GTGGATGTGTGGAGCCTAGGAGTTATCCTCTATACACTGGTCAGCGGATCCCTGCCTTTTGATGGACAGAACCTCAAGGAGCTGCGGGAA
CGGGTACTGAGGGGAAAATACCGTATTCCATTCTACATGTCCACGGACTGTGAAAACCTGCTTAAGAAATTTCTCATTCTTAATCCCAGC
AAGAGAGGCACTTTAGAGCAAATCATGAAAGATCGATGGATGAATGTGGGTCACGAAGATGATGAACTAAAGCCTTACGTGGAGCCACTC
CCTGACTACAAGGACCCCCGGCGGACAGAGCTGATGGTGTCCATGGGTTATACACGGGAAGAGATCCAGGACTCGCTGGTGGGCCAGAGA
TACAACGAGGTGATGGCCACCTATCTGCTCCTGGGCTACAAGAGCTCCGAGCTGGAAGGCGACACCATCACCCTGAAACCCCGGCCTTCA
GCTGATCTGACCAATAGCAGCGCCCCATCCCCATCCCACAAGGTACAGCGCAGCGTGTCGGCCAATCCCAAGCAGCGGCGCTTCAGCGAC
CAGGCAGCTGGTCCTGCCATTCCCACCTCTAATTCTTACTCTAAGAAGACTCAGAGTAACAACGCAGAAAATAAGCGGCCTGAGGAGGAC
CGGGAGTCAGGGCGGAAAGCCAGCAGCACAGCCAAGGTGCCTGCCAGCCCCCTGCCCGGTCTGGAGAGGAAGAAGACCACCCCAACCCCC
TCCACGAACAGCGTCCTCTCCACCAGCACAAATCGAAGCAGGAATTCCCCACTTTTGGAGCGGGCCAGCCTCGGCCAGGCCTCCATCCAG
AATGGCAAAGACAGCCTAACCATGCCAGGGTCCCGGGCCTCCACGGCTTCTGCTTCTGCCGCAGTCTCTGCGGCCCGGCCCCGCCAGCAC
CAGAAATCCATGTCGGCCTCCGTGCACCCCAACAAGGCCTCTGGGCTGCCCCCCACGGAGAGTAACTGTGAGGTGCCGCGGCCCAGCACA
GCCCCCCAGCGTGTCCCTGTTGCCTCCCCATCCGCCCACAACATCAGCAGCAGTGGTGGAGCCCCAGACCGAACTAACTTCCCCCGGGGT
GTGTCCAGCCGAAGCACCTTCCATGCTGGGCAGCTCCGACAGGTGCGGGACCAGCAGAATTTGCCCTACGGTGTGACCCCAGCCTCTCCC
TCTGGCCACAGCCAGGGCCGGCGGGGGGCCTCTGGGAGCATCTTCAGCAAGTTCACCTCCAAGTTTGTACGCAGAAATCTGTCTTTCAGG
TTTGCCAGAAGGAACCTGAATGAACCTGAAAGCAAAGACCGAGTGGAGACGCTCAGACCTCACGTGGTGGGCAGTGGCGGCAACGACAAA
GAAAAGGAAGAATTTCGGGAGGCCAAGCCCCGCTCCCTCCGCTTCACGTGGAGTATGAAGACCACGAGCTCCATGGAGCCCAACGAGATG
ATGCGGGAGATCCGCAAGGTGCTGGACGCGAACAGCTGCCAGAGCGAGCTGCATGAGAAGTACATGCTGCTGTGCATGCACGGCACGCCG
GGCCACGAGGACTTCGTGCAGTGGGAGATGGAGGTGTGCAAACTGCCGCGGCTCTCTCTCAACGGGGTTCGATTTAAGCGGATATCGGGC

>In-frame_PPFIA1_ENST00000253925_chr11_70118542_+_MARK2_ENST00000413835_chr11_63662631_+_2415nt
ATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAGGTGGAGGCCATGGTTCCGGCTCCCCTTCACAGCCA
GATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACCGCCTTCTTGATACACTGAGAGAGACTCAAGAAACG
CTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGCAGAGACAGCTCAACACGGCACTTCCACAGCCCACC
TTGGGACACCTTGACTCCAAGCCCAGCAGTAAGTCCAACATGATTCGGGGCCGCAACTCAGCCACCTCTGCTGATGAGCAGCCCCACATT
GGAAACTACCGGCTCCTCAAGACCATTGGCAAGGGTAATTTTGCCAAGGTGAAGTTGGCCCGACACATCCTGACTGGGAAAGAGGTAGCT
GTGAAGATCATTGACAAGACTCAACTGAACTCCTCCAGCCTCCAGAAACTATTCCGCGAAGTAAGAATAATGAAGGTTTTGAATCATCCC
AACATAGTTAAATTATTTGAAGTGATTGAGACTGAGAAAACGCTCTACCTTGTCATGGAGTACGCTAGTGGCGGAGAGGTATTTGATTAC
CTAGTGGCTCATGGCAGGATGAAAGAAAAAGAGGCTCGAGCCAAATTCCGCCAGATAGTGTCTGCTGTGCAGTACTGTCACCAGAAGTTT
ATTGTCCATAGAGACTTAAAGGCAGAAAACCTGCTCTTGGATGCTGATATGAACATCAAGATTGCAGACTTTGGCTTCAGCAATGAATTC
ACCTTTGGGAACAAGCTGGACACCTTCTGTGGCAGTCCCCCTTATGCTGCCCCAGAACTCTTCCAGGGCAAAAAATATGATGGACCCGAG
GTGGATGTGTGGAGCCTAGGAGTTATCCTCTATACACTGGTCAGCGGATCCCTGCCTTTTGATGGACAGAACCTCAAGGAGCTGCGGGAA
CGGGTACTGAGGGGAAAATACCGTATTCCATTCTACATGTCCACGGACTGTGAAAACCTGCTTAAGAAATTTCTCATTCTTAATCCCAGC
AAGAGAGGCACTTTAGAGCAAATCATGAAAGATCGATGGATGAATGTGGGTCACGAAGATGATGAACTAAAGCCTTACGTGGAGCCACTC
CCTGACTACAAGGACCCCCGGCGGACAGAGCTGATGGTGTCCATGGGTTATACACGGGAAGAGATCCAGGACTCGCTGGTGGGCCAGAGA
TACAACGAGGTGATGGCCACCTATCTGCTCCTGGGCTACAAGAGCTCCGAGCTGGAAGGCGACACCATCACCCTGAAACCCCGGCCTTCA
GCTGATCTGACCAATAGCAGCGCCCCATCCCCATCCCACAAGGTACAGCGCAGCGTGTCGGCCAATCCCAAGCAGCGGCGCTTCAGCGAC
CAGGCAGCTGGTCCTGCCATTCCCACCTCTAATTCTTACTCTAAGAAGACTCAGAGTAACAACGCAGAAAATAAGCGGCCTGAGGAGGAC
CGGGAGTCAGGGCGGAAAGCCAGCAGCACAGCCAAGGTGCCTGCCAGCCCCCTGCCCGGTCTGGAGAGGAAGAAGACCACCCCAACCCCC
TCCACGAACAGCGTCCTCTCCACCAGCACAAATCGAAGCAGGAATTCCCCACTTTTGGAGCGGGCCAGCCTCGGCCAGGCCTCCATCCAG
AATGGCAAAGACAGCACAGCCCCCCAGCGTGTCCCTGTTGCCTCCCCATCCGCCCACAACATCAGCAGCAGTGGTGGAGCCCCAGACCGA
ACTAACTTCCCCCGGGGTGTGTCCAGCCGAAGCACCTTCCATGCTGGGCAGCTCCGACAGGTGCGGGACCAGCAGAATTTGCCCTACGGT
GTGACCCCAGCCTCTCCCTCTGGCCACAGCCAGGGCCGGCGGGGGGCCTCTGGGAGCATCTTCAGCAAGTTCACCTCCAAGTTTGTACGC
AGAAATCTGTCTTTCAGGTTTGCCAGAAGGAACCTGAATGAACCTGAAAGCAAAGACCGAGTGGAGACGCTCAGACCTCACGTGGTGGGC
AGTGGCGGCAACGACAAAGAAAAGGAAGAATTTCGGGAGGCCAAGCCCCGCTCCCTCCGCTTCACGTGGAGTATGAAGACCACGAGCTCC
ATGGAGCCCAACGAGATGATGCGGGAGATCCGCAAGGTGCTGGACGCGAACAGCTGCCAGAGCGAGCTGCATGAGAAGTACATGCTGCTG
TGCATGCACGGCACGCCGGGCCACGAGGACTTCGTGCAGTGGGAGATGGAGGTGTGCAAACTGCCGCGGCTCTCTCTCAACGGGGTTCGA

>In-frame_PPFIA1_ENST00000389547_chr11_70118542_+_MARK2_ENST00000377809_chr11_63662631_+_2532nt
ATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAGGTGGAGGCCATGGTTCCGGCTCCCCTTCACAGCCA
GATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACCGCCTTCTTGATACACTGAGAGAGACTCAAGAAACG
CTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGCAGAGACAGCTCAACACGGCACTTCCACAGCCCACC
TTGGGACACCTTGACTCCAAGCCCAGCAGTAAGTCCAACATGATTCGGGGCCGCAACTCAGCCACCTCTGCTGATGAGCAGCCCCACATT
GGAAACTACCGGCTCCTCAAGACCATTGGCAAGGGTAATTTTGCCAAGGTGAAGTTGGCCCGACACATCCTGACTGGGAAAGAGGTAGCT
GTGAAGATCATTGACAAGACTCAACTGAACTCCTCCAGCCTCCAGAAACTATTCCGCGAAGTAAGAATAATGAAGGTTTTGAATCATCCC
AACATAGTTAAATTATTTGAAGTGATTGAGACTGAGAAAACGCTCTACCTTGTCATGGAGTACGCTAGTGGCGGAGAGGTATTTGATTAC
CTAGTGGCTCATGGCAGGATGAAAGAAAAAGAGGCTCGAGCCAAATTCCGCCAGATAGTGTCTGCTGTGCAGTACTGTCACCAGAAGTTT
ATTGTCCATAGAGACTTAAAGGCAGAAAACCTGCTCTTGGATGCTGATATGAACATCAAGATTGCAGACTTTGGCTTCAGCAATGAATTC
ACCTTTGGGAACAAGCTGGACACCTTCTGTGGCAGTCCCCCTTATGCTGCCCCAGAACTCTTCCAGGGCAAAAAATATGATGGACCCGAG
GTGGATGTGTGGAGCCTAGGAGTTATCCTCTATACACTGGTCAGCGGATCCCTGCCTTTTGATGGACAGAACCTCAAGGAGCTGCGGGAA
CGGGTACTGAGGGGAAAATACCGTATTCCATTCTACATGTCCACGGACTGTGAAAACCTGCTTAAGAAATTTCTCATTCTTAATCCCAGC
AAGAGAGGCACTTTAGAGCAAATCATGAAAGATCGATGGATGAATGTGGGTCACGAAGATGATGAACTAAAGCCTTACGTGGAGCCACTC
CCTGACTACAAGGACCCCCGGCGGACAGAGCTGATGGTGTCCATGGGTTATACACGGGAAGAGATCCAGGACTCGCTGGTGGGCCAGAGA
TACAACGAGGTGATGGCCACCTATCTGCTCCTGGGCTACAAGAGCTCCGAGCTGGAAGGCGACACCATCACCCTGAAACCCCGGCCTTCA
GCTGATCTGACCAATAGCAGCGCCCCATCCCCATCCCACAAGGTACAGCGCAGCGTGTCGGCCAATCCCAAGCAGCGGCGCTTCAGCGAC
CAGGCAGCTGGTCCTGCCATTCCCACCTCTAATTCTTACTCTAAGAAGACTCAGAGTAACAACGCAGAAAATAAGCGGCCTGAGGAGGAC
CGGGAGTCAGGGCGGAAAGCCAGCAGCACAGCCAAGGTGCCTGCCAGCCCCCTGCCCGGTCTGGAGAGGAAGAAGACCACCCCAACCCCC
TCCACGAACAGCGTCCTCTCCACCAGCACAAATCGAAGCAGGAATTCCCCACTTTTGGAGCGGGCCAGCCTCGGCCAGGCCTCCATCCAG
AATGGCAAAGACAGCCTAACCATGCCAGGGTCCCGGGCCTCCACGGCTTCTGCTTCTGCCGCAGTCTCTGCGGCCCGGCCCCGCCAGCAC
CAGAAATCCATGTCGGCCTCCGTGCACCCCAACAAGGCCTCTGGGCTGCCCCCCACGGAGAGTAACTGTGAGGTGCCGCGGCCCAGCACA
GCCCCCCAGCGTGTCCCTGTTGCCTCCCCATCCGCCCACAACATCAGCAGCAGTGGTGGAGCCCCAGACCGAACTAACTTCCCCCGGGGT
GTGTCCAGCCGAAGCACCTTCCATGCTGGGCAGCTCCGACAGGTGCGGGACCAGCAGAATTTGCCCTACGGTGTGACCCCAGCCTCTCCC
TCTGGCCACAGCCAGGGCCGGCGGGGGGCCTCTGGGAGCATCTTCAGCAAGTTCACCTCCAAGTTTGTACGCAGAAATCTGTCTTTCAGG
TTTGCCAGAAGACCTCACGTGGTGGGCAGTGGCGGCAACGACAAAGAAAAGGAAGAATTTCGGGAGGCCAAGCCCCGCTCCCTCCGCTTC
ACGTGGAGTATGAAGACCACGAGCTCCATGGAGCCCAACGAGATGATGCGGGAGATCCGCAAGGTGCTGGACGCGAACAGCTGCCAGAGC
GAGCTGCATGAGAAGTACATGCTGCTGTGCATGCACGGCACGCCGGGCCACGAGGACTTCGTGCAGTGGGAGATGGAGGTGTGCAAACTG
CCGCGGCTCTCTCTCAACGGGGTTCGATTTAAGCGGATATCGGGCACCTCCATGGCCTTCAAAAACATTGCCTCCAAAATAGCCAACGAG

>In-frame_PPFIA1_ENST00000389547_chr11_70118542_+_MARK2_ENST00000402010_chr11_63662631_+_2577nt
ATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAGGTGGAGGCCATGGTTCCGGCTCCCCTTCACAGCCA
GATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACCGCCTTCTTGATACACTGAGAGAGACTCAAGAAACG
CTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGCAGAGACAGCTCAACACGGCACTTCCACAGCCCACC
TTGGGACACCTTGACTCCAAGCCCAGCAGTAAGTCCAACATGATTCGGGGCCGCAACTCAGCCACCTCTGCTGATGAGCAGCCCCACATT
GGAAACTACCGGCTCCTCAAGACCATTGGCAAGGGTAATTTTGCCAAGGTGAAGTTGGCCCGACACATCCTGACTGGGAAAGAGGTAGCT
GTGAAGATCATTGACAAGACTCAACTGAACTCCTCCAGCCTCCAGAAACTATTCCGCGAAGTAAGAATAATGAAGGTTTTGAATCATCCC
AACATAGTTAAATTATTTGAAGTGATTGAGACTGAGAAAACGCTCTACCTTGTCATGGAGTACGCTAGTGGCGGAGAGGTATTTGATTAC
CTAGTGGCTCATGGCAGGATGAAAGAAAAAGAGGCTCGAGCCAAATTCCGCCAGATAGTGTCTGCTGTGCAGTACTGTCACCAGAAGTTT
ATTGTCCATAGAGACTTAAAGGCAGAAAACCTGCTCTTGGATGCTGATATGAACATCAAGATTGCAGACTTTGGCTTCAGCAATGAATTC
ACCTTTGGGAACAAGCTGGACACCTTCTGTGGCAGTCCCCCTTATGCTGCCCCAGAACTCTTCCAGGGCAAAAAATATGATGGACCCGAG
GTGGATGTGTGGAGCCTAGGAGTTATCCTCTATACACTGGTCAGCGGATCCCTGCCTTTTGATGGACAGAACCTCAAGGAGCTGCGGGAA
CGGGTACTGAGGGGAAAATACCGTATTCCATTCTACATGTCCACGGACTGTGAAAACCTGCTTAAGAAATTTCTCATTCTTAATCCCAGC
AAGAGAGGCACTTTAGAGCAAATCATGAAAGATCGATGGATGAATGTGGGTCACGAAGATGATGAACTAAAGCCTTACGTGGAGCCACTC
CCTGACTACAAGGACCCCCGGCGGACAGAGCTGATGGTGTCCATGGGTTATACACGGGAAGAGATCCAGGACTCGCTGGTGGGCCAGAGA
TACAACGAGGTGATGGCCACCTATCTGCTCCTGGGCTACAAGAGCTCCGAGCTGGAAGGCGACACCATCACCCTGAAACCCCGGCCTTCA
GCTGATCTGACCAATAGCAGCGCCCCATCCCCATCCCACAAGGTACAGCGCAGCGTGTCGGCCAATCCCAAGCAGCGGCGCTTCAGCGAC
CAGGCAGCTGGTCCTGCCATTCCCACCTCTAATTCTTACTCTAAGAAGACTCAGAGTAACAACGCAGAAAATAAGCGGCCTGAGGAGGAC
CGGGAGTCAGGGCGGAAAGCCAGCAGCACAGCCAAGGTGCCTGCCAGCCCCCTGCCCGGTCTGGAGAGGAAGAAGACCACCCCAACCCCC
TCCACGAACAGCGTCCTCTCCACCAGCACAAATCGAAGCAGGAATTCCCCACTTTTGGAGCGGGCCAGCCTCGGCCAGGCCTCCATCCAG
AATGGCAAAGACAGCCTAACCATGCCAGGGTCCCGGGCCTCCACGGCTTCTGCTTCTGCCGCAGTCTCTGCGGCCCGGCCCCGCCAGCAC
CAGAAATCCATGTCGGCCTCCGTGCACCCCAACAAGGCCTCTGGGCTGCCCCCCACGGAGAGTAACTGTGAGGTGCCGCGGCCCAGCACA
GCCCCCCAGCGTGTCCCTGTTGCCTCCCCATCCGCCCACAACATCAGCAGCAGTGGTGGAGCCCCAGACCGAACTAACTTCCCCCGGGGT
GTGTCCAGCCGAAGCACCTTCCATGCTGGGCAGCTCCGACAGGTGCGGGACCAGCAGAATTTGCCCTACGGTGTGACCCCAGCCTCTCCC
TCTGGCCACAGCCAGGGCCGGCGGGGGGCCTCTGGGAGCATCTTCAGCAAGTTCACCTCCAAGTTTGTACGCAGAAATCTGTCTTTCAGG
TTTGCCAGAAGGAACCTGAATGAACCTGAAAGCAAAGACCGAGTGGAGACGCTCAGACCTCACGTGGTGGGCAGTGGCGGCAACGACAAA
GAAAAGGAAGAATTTCGGGAGGCCAAGCCCCGCTCCCTCCGCTTCACGTGGAGTATGAAGACCACGAGCTCCATGGAGCCCAACGAGATG
ATGCGGGAGATCCGCAAGGTGCTGGACGCGAACAGCTGCCAGAGCGAGCTGCATGAGAAGTACATGCTGCTGTGCATGCACGGCACGCCG
GGCCACGAGGACTTCGTGCAGTGGGAGATGGAGGTGTGCAAACTGCCGCGGCTCTCTCTCAACGGGGTTCGATTTAAGCGGATATCGGGC

>In-frame_PPFIA1_ENST00000389547_chr11_70118542_+_MARK2_ENST00000413835_chr11_63662631_+_2415nt
ATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAGGTGGAGGCCATGGTTCCGGCTCCCCTTCACAGCCA
GATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACCGCCTTCTTGATACACTGAGAGAGACTCAAGAAACG
CTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGCAGAGACAGCTCAACACGGCACTTCCACAGCCCACC
TTGGGACACCTTGACTCCAAGCCCAGCAGTAAGTCCAACATGATTCGGGGCCGCAACTCAGCCACCTCTGCTGATGAGCAGCCCCACATT
GGAAACTACCGGCTCCTCAAGACCATTGGCAAGGGTAATTTTGCCAAGGTGAAGTTGGCCCGACACATCCTGACTGGGAAAGAGGTAGCT
GTGAAGATCATTGACAAGACTCAACTGAACTCCTCCAGCCTCCAGAAACTATTCCGCGAAGTAAGAATAATGAAGGTTTTGAATCATCCC
AACATAGTTAAATTATTTGAAGTGATTGAGACTGAGAAAACGCTCTACCTTGTCATGGAGTACGCTAGTGGCGGAGAGGTATTTGATTAC
CTAGTGGCTCATGGCAGGATGAAAGAAAAAGAGGCTCGAGCCAAATTCCGCCAGATAGTGTCTGCTGTGCAGTACTGTCACCAGAAGTTT
ATTGTCCATAGAGACTTAAAGGCAGAAAACCTGCTCTTGGATGCTGATATGAACATCAAGATTGCAGACTTTGGCTTCAGCAATGAATTC
ACCTTTGGGAACAAGCTGGACACCTTCTGTGGCAGTCCCCCTTATGCTGCCCCAGAACTCTTCCAGGGCAAAAAATATGATGGACCCGAG
GTGGATGTGTGGAGCCTAGGAGTTATCCTCTATACACTGGTCAGCGGATCCCTGCCTTTTGATGGACAGAACCTCAAGGAGCTGCGGGAA
CGGGTACTGAGGGGAAAATACCGTATTCCATTCTACATGTCCACGGACTGTGAAAACCTGCTTAAGAAATTTCTCATTCTTAATCCCAGC
AAGAGAGGCACTTTAGAGCAAATCATGAAAGATCGATGGATGAATGTGGGTCACGAAGATGATGAACTAAAGCCTTACGTGGAGCCACTC
CCTGACTACAAGGACCCCCGGCGGACAGAGCTGATGGTGTCCATGGGTTATACACGGGAAGAGATCCAGGACTCGCTGGTGGGCCAGAGA
TACAACGAGGTGATGGCCACCTATCTGCTCCTGGGCTACAAGAGCTCCGAGCTGGAAGGCGACACCATCACCCTGAAACCCCGGCCTTCA
GCTGATCTGACCAATAGCAGCGCCCCATCCCCATCCCACAAGGTACAGCGCAGCGTGTCGGCCAATCCCAAGCAGCGGCGCTTCAGCGAC
CAGGCAGCTGGTCCTGCCATTCCCACCTCTAATTCTTACTCTAAGAAGACTCAGAGTAACAACGCAGAAAATAAGCGGCCTGAGGAGGAC
CGGGAGTCAGGGCGGAAAGCCAGCAGCACAGCCAAGGTGCCTGCCAGCCCCCTGCCCGGTCTGGAGAGGAAGAAGACCACCCCAACCCCC
TCCACGAACAGCGTCCTCTCCACCAGCACAAATCGAAGCAGGAATTCCCCACTTTTGGAGCGGGCCAGCCTCGGCCAGGCCTCCATCCAG
AATGGCAAAGACAGCACAGCCCCCCAGCGTGTCCCTGTTGCCTCCCCATCCGCCCACAACATCAGCAGCAGTGGTGGAGCCCCAGACCGA
ACTAACTTCCCCCGGGGTGTGTCCAGCCGAAGCACCTTCCATGCTGGGCAGCTCCGACAGGTGCGGGACCAGCAGAATTTGCCCTACGGT
GTGACCCCAGCCTCTCCCTCTGGCCACAGCCAGGGCCGGCGGGGGGCCTCTGGGAGCATCTTCAGCAAGTTCACCTCCAAGTTTGTACGC
AGAAATCTGTCTTTCAGGTTTGCCAGAAGGAACCTGAATGAACCTGAAAGCAAAGACCGAGTGGAGACGCTCAGACCTCACGTGGTGGGC
AGTGGCGGCAACGACAAAGAAAAGGAAGAATTTCGGGAGGCCAAGCCCCGCTCCCTCCGCTTCACGTGGAGTATGAAGACCACGAGCTCC
ATGGAGCCCAACGAGATGATGCGGGAGATCCGCAAGGTGCTGGACGCGAACAGCTGCCAGAGCGAGCTGCATGAGAAGTACATGCTGCTG
TGCATGCACGGCACGCCGGGCCACGAGGACTTCGTGCAGTGGGAGATGGAGGTGTGCAAACTGCCGCGGCTCTCTCTCAACGGGGTTCGA


* Fusion transcript sequences (Full-length transcript).
>In-frame_PPFIA1_ENST00000253925_chr11_70118542_+_MARK2_ENST00000377809_chr11_63662631_+_4529nt
GCCGCGCAGCCGGGCCCGCTCCTCCTCCGCTCCGCCAGTGTCCGGCCGCGGGCCGGCCTTAGTGACTGGGGCGGCGGGCCCCGGGGCCGC
GGCGTGGGGCGGGCAGGCGGACGCCGGCCGCGGGCTGCTTTCGTCGGCTCCCAAGCTCTCCCGGAGCGAGCAGCCGCCCGCGAGCCGCCG
CGGAGCCTCCTCGCCCGCTCCCGCCGGCGAGCAAGATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAG
GTGGAGGCCATGGTTCCGGCTCCCCTTCACAGCCAGATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACC
GCCTTCTTGATACACTGAGAGAGACTCAAGAAACGCTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGC
AGAGACAGCTCAACACGGCACTTCCACAGCCCACCTTGGGACACCTTGACTCCAAGCCCAGCAGTAAGTCCAACATGATTCGGGGCCGCA
ACTCAGCCACCTCTGCTGATGAGCAGCCCCACATTGGAAACTACCGGCTCCTCAAGACCATTGGCAAGGGTAATTTTGCCAAGGTGAAGT
TGGCCCGACACATCCTGACTGGGAAAGAGGTAGCTGTGAAGATCATTGACAAGACTCAACTGAACTCCTCCAGCCTCCAGAAACTATTCC
GCGAAGTAAGAATAATGAAGGTTTTGAATCATCCCAACATAGTTAAATTATTTGAAGTGATTGAGACTGAGAAAACGCTCTACCTTGTCA
TGGAGTACGCTAGTGGCGGAGAGGTATTTGATTACCTAGTGGCTCATGGCAGGATGAAAGAAAAAGAGGCTCGAGCCAAATTCCGCCAGA
TAGTGTCTGCTGTGCAGTACTGTCACCAGAAGTTTATTGTCCATAGAGACTTAAAGGCAGAAAACCTGCTCTTGGATGCTGATATGAACA
TCAAGATTGCAGACTTTGGCTTCAGCAATGAATTCACCTTTGGGAACAAGCTGGACACCTTCTGTGGCAGTCCCCCTTATGCTGCCCCAG
AACTCTTCCAGGGCAAAAAATATGATGGACCCGAGGTGGATGTGTGGAGCCTAGGAGTTATCCTCTATACACTGGTCAGCGGATCCCTGC
CTTTTGATGGACAGAACCTCAAGGAGCTGCGGGAACGGGTACTGAGGGGAAAATACCGTATTCCATTCTACATGTCCACGGACTGTGAAA
ACCTGCTTAAGAAATTTCTCATTCTTAATCCCAGCAAGAGAGGCACTTTAGAGCAAATCATGAAAGATCGATGGATGAATGTGGGTCACG
AAGATGATGAACTAAAGCCTTACGTGGAGCCACTCCCTGACTACAAGGACCCCCGGCGGACAGAGCTGATGGTGTCCATGGGTTATACAC
GGGAAGAGATCCAGGACTCGCTGGTGGGCCAGAGATACAACGAGGTGATGGCCACCTATCTGCTCCTGGGCTACAAGAGCTCCGAGCTGG
AAGGCGACACCATCACCCTGAAACCCCGGCCTTCAGCTGATCTGACCAATAGCAGCGCCCCATCCCCATCCCACAAGGTACAGCGCAGCG
TGTCGGCCAATCCCAAGCAGCGGCGCTTCAGCGACCAGGCAGCTGGTCCTGCCATTCCCACCTCTAATTCTTACTCTAAGAAGACTCAGA
GTAACAACGCAGAAAATAAGCGGCCTGAGGAGGACCGGGAGTCAGGGCGGAAAGCCAGCAGCACAGCCAAGGTGCCTGCCAGCCCCCTGC
CCGGTCTGGAGAGGAAGAAGACCACCCCAACCCCCTCCACGAACAGCGTCCTCTCCACCAGCACAAATCGAAGCAGGAATTCCCCACTTT
TGGAGCGGGCCAGCCTCGGCCAGGCCTCCATCCAGAATGGCAAAGACAGCCTAACCATGCCAGGGTCCCGGGCCTCCACGGCTTCTGCTT
CTGCCGCAGTCTCTGCGGCCCGGCCCCGCCAGCACCAGAAATCCATGTCGGCCTCCGTGCACCCCAACAAGGCCTCTGGGCTGCCCCCCA
CGGAGAGTAACTGTGAGGTGCCGCGGCCCAGCACAGCCCCCCAGCGTGTCCCTGTTGCCTCCCCATCCGCCCACAACATCAGCAGCAGTG
GTGGAGCCCCAGACCGAACTAACTTCCCCCGGGGTGTGTCCAGCCGAAGCACCTTCCATGCTGGGCAGCTCCGACAGGTGCGGGACCAGC
AGAATTTGCCCTACGGTGTGACCCCAGCCTCTCCCTCTGGCCACAGCCAGGGCCGGCGGGGGGCCTCTGGGAGCATCTTCAGCAAGTTCA
CCTCCAAGTTTGTACGCAGAAATCTGTCTTTCAGGTTTGCCAGAAGACCTCACGTGGTGGGCAGTGGCGGCAACGACAAAGAAAAGGAAG
AATTTCGGGAGGCCAAGCCCCGCTCCCTCCGCTTCACGTGGAGTATGAAGACCACGAGCTCCATGGAGCCCAACGAGATGATGCGGGAGA
TCCGCAAGGTGCTGGACGCGAACAGCTGCCAGAGCGAGCTGCATGAGAAGTACATGCTGCTGTGCATGCACGGCACGCCGGGCCACGAGG
ACTTCGTGCAGTGGGAGATGGAGGTGTGCAAACTGCCGCGGCTCTCTCTCAACGGGGTTCGATTTAAGCGGATATCGGGCACCTCCATGG
CCTTCAAAAACATTGCCTCCAAAATAGCCAACGAGCTGAAGCTTTAACAGGCTGCCAGGAGCGGGGGCGGCGGGGGCGGGCCAGCTGGAC
GGGCTGCCGGCCGCTGCGCCGCCCCACCTGGGCGAGACTGCAGCGATGGATTGGTGTGTCTCCCCTGCTGGCACTTCTCCCCTCCCTGGC
CCTTCTCAGTTTTCTCTTACATGTTTGTGGGGGGTGGGAGATTGTTCTCCAGCACCCCACATTCACCCCTGCCCAGAGATTCCCCCTTCT
CCTCTCCCCTACTGGAGGCAAAGGAAGGGGAGGGTGGATGGGGGGGCAGGGCTCCCCCTCGGTACTGCGGTTGCACAGAGTATTTCGCCT
AAACCAAGAAATTTTTTATTACCAAAAAGAAAAAAGAAAAAAAAAATCCCAGCGGCCACCTTTCCTCCCTGCCCCATTGGGACAGTCGAG
ACTGGATCTGTGGGGTTTCCCGGGAGGGTGGCTCAGGGCTGGAACACTCTCAGGCAAGAGTGGTGGAGCTCCCGTCAGGCCCTCCGCCAG
GCCCACTGTGGGCTTCTCCCCTCTCCTCCCTCCTTCCCCTCCAAGCAAACCACCAGAGGTGGCCTTCCCCTGACCTCAGGCCCCTGGGCT
GGAGGCCTGGGCGGTGGGGCAGGGGGCGGGGGTGCTGCGCAGCCCTGCAGTGGGTGGGGCTGGGGGCTGCTCCGGGGCTGCTGAGGCTGG
AGGGCCGGCACAAGGCTCCGCCTCCCTCCACACTGTACCCTCTGCCCCTCCTCCCCAGAGCTGGGCATTTCCTTCCACAAGCTGCTGTGG
GGACGTGTGTTCCCTCAAAGTCTGTGCCATCTTCTCCCACCCCTCCCGGGTAGAAGGAGGGGCTGACCCCAGGGCTGGGAGAGGGGAGGG
GACTGGAGGGCAGACTGGCTTCTCGGTCCCCAGGGGGCCGCTTGGGCTGTTGGTCTCCAGAGCAGGGCCACTGGGCACTCTGTGATGGGG
GAGCCTTTGTCTGAAAGCACAGCCCCCTCGCCCTTCCTCTCCCCATGGCTTCCCCTTCATTGGCATTAATCTGGGCACCAGCTCTCTCCA
TAGCAGTGACTTCCCTCACCACTCTCATCTCTCAGCCTTGCCTTTTCTTCCTGACACTGTCGCCCCCTCCTCTCAGGAGACACTGCCGAG
GGCCACCTGGCAGAAGGCTGAGTTAGGCAGCAGGGCCGGGAGCGTCTGCCCTCCACAGGGTGGGGGACAGATAGGCTAAGCGACTCCCAG
CTTGCTACCCTCAGTGGCCAGTGTGGGCGTGGGCGGTTTGGGGCGCTTGGCTGGTGGTGGCCACTGCATCCCTTAATTTATTTCTCTGCT
GTTTCTGTTCTTGAGAAATTGGGGGTGGGAGTCCTACACAGAGGCTGCCCCTACCCTCACCTGAGTTGTACATTTTTTTGTGATGGGTTT
TATTTTTTATTATTTTATTTTATTTTTTTTTTTTTTGATTTATGATGACTCCACCCCTCTTCATCACCCCCGCTCCCAGGCCAGGCTCAG
CGATTAAGCCGAGCCCTTGCGTCCTAGGAAGGGGCCTTGCCAACCTCAGCCCTCCTGCCCCACACTCCTACTGCGGCTCAGACCAAGGGC
TCCCCCTCCCTCCCTTCCCCCCTCCTGCCCTATGGAACAGCCCGGGTGCTCTGAGGGGGCTGGGAGGGCATGGCTTGGCTCCCAAAGGGG
GTAGGGGCCCGGGGCACCCAGGCAAGGTGGCCCCTCCCCGTCTAGCCCCCTCCTCCCCAACCCTGCACTTAGTTTCTCCTCTGGATCAAA

>In-frame_PPFIA1_ENST00000253925_chr11_70118542_+_MARK2_ENST00000402010_chr11_63662631_+_4574nt
GCCGCGCAGCCGGGCCCGCTCCTCCTCCGCTCCGCCAGTGTCCGGCCGCGGGCCGGCCTTAGTGACTGGGGCGGCGGGCCCCGGGGCCGC
GGCGTGGGGCGGGCAGGCGGACGCCGGCCGCGGGCTGCTTTCGTCGGCTCCCAAGCTCTCCCGGAGCGAGCAGCCGCCCGCGAGCCGCCG
CGGAGCCTCCTCGCCCGCTCCCGCCGGCGAGCAAGATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAG
GTGGAGGCCATGGTTCCGGCTCCCCTTCACAGCCAGATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACC
GCCTTCTTGATACACTGAGAGAGACTCAAGAAACGCTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGC
AGAGACAGCTCAACACGGCACTTCCACAGCCCACCTTGGGACACCTTGACTCCAAGCCCAGCAGTAAGTCCAACATGATTCGGGGCCGCA
ACTCAGCCACCTCTGCTGATGAGCAGCCCCACATTGGAAACTACCGGCTCCTCAAGACCATTGGCAAGGGTAATTTTGCCAAGGTGAAGT
TGGCCCGACACATCCTGACTGGGAAAGAGGTAGCTGTGAAGATCATTGACAAGACTCAACTGAACTCCTCCAGCCTCCAGAAACTATTCC
GCGAAGTAAGAATAATGAAGGTTTTGAATCATCCCAACATAGTTAAATTATTTGAAGTGATTGAGACTGAGAAAACGCTCTACCTTGTCA
TGGAGTACGCTAGTGGCGGAGAGGTATTTGATTACCTAGTGGCTCATGGCAGGATGAAAGAAAAAGAGGCTCGAGCCAAATTCCGCCAGA
TAGTGTCTGCTGTGCAGTACTGTCACCAGAAGTTTATTGTCCATAGAGACTTAAAGGCAGAAAACCTGCTCTTGGATGCTGATATGAACA
TCAAGATTGCAGACTTTGGCTTCAGCAATGAATTCACCTTTGGGAACAAGCTGGACACCTTCTGTGGCAGTCCCCCTTATGCTGCCCCAG
AACTCTTCCAGGGCAAAAAATATGATGGACCCGAGGTGGATGTGTGGAGCCTAGGAGTTATCCTCTATACACTGGTCAGCGGATCCCTGC
CTTTTGATGGACAGAACCTCAAGGAGCTGCGGGAACGGGTACTGAGGGGAAAATACCGTATTCCATTCTACATGTCCACGGACTGTGAAA
ACCTGCTTAAGAAATTTCTCATTCTTAATCCCAGCAAGAGAGGCACTTTAGAGCAAATCATGAAAGATCGATGGATGAATGTGGGTCACG
AAGATGATGAACTAAAGCCTTACGTGGAGCCACTCCCTGACTACAAGGACCCCCGGCGGACAGAGCTGATGGTGTCCATGGGTTATACAC
GGGAAGAGATCCAGGACTCGCTGGTGGGCCAGAGATACAACGAGGTGATGGCCACCTATCTGCTCCTGGGCTACAAGAGCTCCGAGCTGG
AAGGCGACACCATCACCCTGAAACCCCGGCCTTCAGCTGATCTGACCAATAGCAGCGCCCCATCCCCATCCCACAAGGTACAGCGCAGCG
TGTCGGCCAATCCCAAGCAGCGGCGCTTCAGCGACCAGGCAGCTGGTCCTGCCATTCCCACCTCTAATTCTTACTCTAAGAAGACTCAGA
GTAACAACGCAGAAAATAAGCGGCCTGAGGAGGACCGGGAGTCAGGGCGGAAAGCCAGCAGCACAGCCAAGGTGCCTGCCAGCCCCCTGC
CCGGTCTGGAGAGGAAGAAGACCACCCCAACCCCCTCCACGAACAGCGTCCTCTCCACCAGCACAAATCGAAGCAGGAATTCCCCACTTT
TGGAGCGGGCCAGCCTCGGCCAGGCCTCCATCCAGAATGGCAAAGACAGCCTAACCATGCCAGGGTCCCGGGCCTCCACGGCTTCTGCTT
CTGCCGCAGTCTCTGCGGCCCGGCCCCGCCAGCACCAGAAATCCATGTCGGCCTCCGTGCACCCCAACAAGGCCTCTGGGCTGCCCCCCA
CGGAGAGTAACTGTGAGGTGCCGCGGCCCAGCACAGCCCCCCAGCGTGTCCCTGTTGCCTCCCCATCCGCCCACAACATCAGCAGCAGTG
GTGGAGCCCCAGACCGAACTAACTTCCCCCGGGGTGTGTCCAGCCGAAGCACCTTCCATGCTGGGCAGCTCCGACAGGTGCGGGACCAGC
AGAATTTGCCCTACGGTGTGACCCCAGCCTCTCCCTCTGGCCACAGCCAGGGCCGGCGGGGGGCCTCTGGGAGCATCTTCAGCAAGTTCA
CCTCCAAGTTTGTACGCAGAAATCTGTCTTTCAGGTTTGCCAGAAGGAACCTGAATGAACCTGAAAGCAAAGACCGAGTGGAGACGCTCA
GACCTCACGTGGTGGGCAGTGGCGGCAACGACAAAGAAAAGGAAGAATTTCGGGAGGCCAAGCCCCGCTCCCTCCGCTTCACGTGGAGTA
TGAAGACCACGAGCTCCATGGAGCCCAACGAGATGATGCGGGAGATCCGCAAGGTGCTGGACGCGAACAGCTGCCAGAGCGAGCTGCATG
AGAAGTACATGCTGCTGTGCATGCACGGCACGCCGGGCCACGAGGACTTCGTGCAGTGGGAGATGGAGGTGTGCAAACTGCCGCGGCTCT
CTCTCAACGGGGTTCGATTTAAGCGGATATCGGGCACCTCCATGGCCTTCAAAAACATTGCCTCCAAAATAGCCAACGAGCTGAAGCTTT
AACAGGCTGCCAGGAGCGGGGGCGGCGGGGGCGGGCCAGCTGGACGGGCTGCCGGCCGCTGCGCCGCCCCACCTGGGCGAGACTGCAGCG
ATGGATTGGTGTGTCTCCCCTGCTGGCACTTCTCCCCTCCCTGGCCCTTCTCAGTTTTCTCTTACATGTTTGTGGGGGGTGGGAGATTGT
TCTCCAGCACCCCACATTCACCCCTGCCCAGAGATTCCCCCTTCTCCTCTCCCCTACTGGAGGCAAAGGAAGGGGAGGGTGGATGGGGGG
GCAGGGCTCCCCCTCGGTACTGCGGTTGCACAGAGTATTTCGCCTAAACCAAGAAATTTTTTATTACCAAAAAGAAAAAAGAAAAAAAAA
ATCCCAGCGGCCACCTTTCCTCCCTGCCCCATTGGGACAGTCGAGACTGGATCTGTGGGGTTTCCCGGGAGGGTGGCTCAGGGCTGGAAC
ACTCTCAGGCAAGAGTGGTGGAGCTCCCGTCAGGCCCTCCGCCAGGCCCACTGTGGGCTTCTCCCCTCTCCTCCCTCCTTCCCCTCCAAG
CAAACCACCAGAGGTGGCCTTCCCCTGACCTCAGGCCCCTGGGCTGGAGGCCTGGGCGGTGGGGCAGGGGGCGGGGGTGCTGCGCAGCCC
TGCAGTGGGTGGGGCTGGGGGCTGCTCCGGGGCTGCTGAGGCTGGAGGGCCGGCACAAGGCTCCGCCTCCCTCCACACTGTACCCTCTGC
CCCTCCTCCCCAGAGCTGGGCATTTCCTTCCACAAGCTGCTGTGGGGACGTGTGTTCCCTCAAAGTCTGTGCCATCTTCTCCCACCCCTC
CCGGGTAGAAGGAGGGGCTGACCCCAGGGCTGGGAGAGGGGAGGGGACTGGAGGGCAGACTGGCTTCTCGGTCCCCAGGGGGCCGCTTGG
GCTGTTGGTCTCCAGAGCAGGGCCACTGGGCACTCTGTGATGGGGGAGCCTTTGTCTGAAAGCACAGCCCCCTCGCCCTTCCTCTCCCCA
TGGCTTCCCCTTCATTGGCATTAATCTGGGCACCAGCTCTCTCCATAGCAGTGACTTCCCTCACCACTCTCATCTCTCAGCCTTGCCTTT
TCTTCCTGACACTGTCGCCCCCTCCTCTCAGGAGACACTGCCGAGGGCCACCTGGCAGAAGGCTGAGTTAGGCAGCAGGGCCGGGAGCGT
CTGCCCTCCACAGGGTGGGGGACAGATAGGCTAAGCGACTCCCAGCTTGCTACCCTCAGTGGCCAGTGTGGGCGTGGGCGGTTTGGGGCG
CTTGGCTGGTGGTGGCCACTGCATCCCTTAATTTATTTCTCTGCTGTTTCTGTTCTTGAGAAATTGGGGGTGGGAGTCCTACACAGAGGC
TGCCCCTACCCTCACCTGAGTTGTACATTTTTTTGTGATGGGTTTTATTTTTTATTATTTTATTTTATTTTTTTTTTTTTTGATTTATGA
TGACTCCACCCCTCTTCATCACCCCCGCTCCCAGGCCAGGCTCAGCGATTAAGCCGAGCCCTTGCGTCCTAGGAAGGGGCCTTGCCAACC
TCAGCCCTCCTGCCCCACACTCCTACTGCGGCTCAGACCAAGGGCTCCCCCTCCCTCCCTTCCCCCCTCCTGCCCTATGGAACAGCCCGG
GTGCTCTGAGGGGGCTGGGAGGGCATGGCTTGGCTCCCAAAGGGGGTAGGGGCCCGGGGCACCCAGGCAAGGTGGCCCCTCCCCGTCTAG

>In-frame_PPFIA1_ENST00000253925_chr11_70118542_+_MARK2_ENST00000413835_chr11_63662631_+_4412nt
GCCGCGCAGCCGGGCCCGCTCCTCCTCCGCTCCGCCAGTGTCCGGCCGCGGGCCGGCCTTAGTGACTGGGGCGGCGGGCCCCGGGGCCGC
GGCGTGGGGCGGGCAGGCGGACGCCGGCCGCGGGCTGCTTTCGTCGGCTCCCAAGCTCTCCCGGAGCGAGCAGCCGCCCGCGAGCCGCCG
CGGAGCCTCCTCGCCCGCTCCCGCCGGCGAGCAAGATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAG
GTGGAGGCCATGGTTCCGGCTCCCCTTCACAGCCAGATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACC
GCCTTCTTGATACACTGAGAGAGACTCAAGAAACGCTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGC
AGAGACAGCTCAACACGGCACTTCCACAGCCCACCTTGGGACACCTTGACTCCAAGCCCAGCAGTAAGTCCAACATGATTCGGGGCCGCA
ACTCAGCCACCTCTGCTGATGAGCAGCCCCACATTGGAAACTACCGGCTCCTCAAGACCATTGGCAAGGGTAATTTTGCCAAGGTGAAGT
TGGCCCGACACATCCTGACTGGGAAAGAGGTAGCTGTGAAGATCATTGACAAGACTCAACTGAACTCCTCCAGCCTCCAGAAACTATTCC
GCGAAGTAAGAATAATGAAGGTTTTGAATCATCCCAACATAGTTAAATTATTTGAAGTGATTGAGACTGAGAAAACGCTCTACCTTGTCA
TGGAGTACGCTAGTGGCGGAGAGGTATTTGATTACCTAGTGGCTCATGGCAGGATGAAAGAAAAAGAGGCTCGAGCCAAATTCCGCCAGA
TAGTGTCTGCTGTGCAGTACTGTCACCAGAAGTTTATTGTCCATAGAGACTTAAAGGCAGAAAACCTGCTCTTGGATGCTGATATGAACA
TCAAGATTGCAGACTTTGGCTTCAGCAATGAATTCACCTTTGGGAACAAGCTGGACACCTTCTGTGGCAGTCCCCCTTATGCTGCCCCAG
AACTCTTCCAGGGCAAAAAATATGATGGACCCGAGGTGGATGTGTGGAGCCTAGGAGTTATCCTCTATACACTGGTCAGCGGATCCCTGC
CTTTTGATGGACAGAACCTCAAGGAGCTGCGGGAACGGGTACTGAGGGGAAAATACCGTATTCCATTCTACATGTCCACGGACTGTGAAA
ACCTGCTTAAGAAATTTCTCATTCTTAATCCCAGCAAGAGAGGCACTTTAGAGCAAATCATGAAAGATCGATGGATGAATGTGGGTCACG
AAGATGATGAACTAAAGCCTTACGTGGAGCCACTCCCTGACTACAAGGACCCCCGGCGGACAGAGCTGATGGTGTCCATGGGTTATACAC
GGGAAGAGATCCAGGACTCGCTGGTGGGCCAGAGATACAACGAGGTGATGGCCACCTATCTGCTCCTGGGCTACAAGAGCTCCGAGCTGG
AAGGCGACACCATCACCCTGAAACCCCGGCCTTCAGCTGATCTGACCAATAGCAGCGCCCCATCCCCATCCCACAAGGTACAGCGCAGCG
TGTCGGCCAATCCCAAGCAGCGGCGCTTCAGCGACCAGGCAGCTGGTCCTGCCATTCCCACCTCTAATTCTTACTCTAAGAAGACTCAGA
GTAACAACGCAGAAAATAAGCGGCCTGAGGAGGACCGGGAGTCAGGGCGGAAAGCCAGCAGCACAGCCAAGGTGCCTGCCAGCCCCCTGC
CCGGTCTGGAGAGGAAGAAGACCACCCCAACCCCCTCCACGAACAGCGTCCTCTCCACCAGCACAAATCGAAGCAGGAATTCCCCACTTT
TGGAGCGGGCCAGCCTCGGCCAGGCCTCCATCCAGAATGGCAAAGACAGCACAGCCCCCCAGCGTGTCCCTGTTGCCTCCCCATCCGCCC
ACAACATCAGCAGCAGTGGTGGAGCCCCAGACCGAACTAACTTCCCCCGGGGTGTGTCCAGCCGAAGCACCTTCCATGCTGGGCAGCTCC
GACAGGTGCGGGACCAGCAGAATTTGCCCTACGGTGTGACCCCAGCCTCTCCCTCTGGCCACAGCCAGGGCCGGCGGGGGGCCTCTGGGA
GCATCTTCAGCAAGTTCACCTCCAAGTTTGTACGCAGAAATCTGTCTTTCAGGTTTGCCAGAAGGAACCTGAATGAACCTGAAAGCAAAG
ACCGAGTGGAGACGCTCAGACCTCACGTGGTGGGCAGTGGCGGCAACGACAAAGAAAAGGAAGAATTTCGGGAGGCCAAGCCCCGCTCCC
TCCGCTTCACGTGGAGTATGAAGACCACGAGCTCCATGGAGCCCAACGAGATGATGCGGGAGATCCGCAAGGTGCTGGACGCGAACAGCT
GCCAGAGCGAGCTGCATGAGAAGTACATGCTGCTGTGCATGCACGGCACGCCGGGCCACGAGGACTTCGTGCAGTGGGAGATGGAGGTGT
GCAAACTGCCGCGGCTCTCTCTCAACGGGGTTCGATTTAAGCGGATATCGGGCACCTCCATGGCCTTCAAAAACATTGCCTCCAAAATAG
CCAACGAGCTGAAGCTTTAACAGGCTGCCAGGAGCGGGGGCGGCGGGGGCGGGCCAGCTGGACGGGCTGCCGGCCGCTGCGCCGCCCCAC
CTGGGCGAGACTGCAGCGATGGATTGGTGTGTCTCCCCTGCTGGCACTTCTCCCCTCCCTGGCCCTTCTCAGTTTTCTCTTACATGTTTG
TGGGGGGTGGGAGATTGTTCTCCAGCACCCCACATTCACCCCTGCCCAGAGATTCCCCCTTCTCCTCTCCCCTACTGGAGGCAAAGGAAG
GGGAGGGTGGATGGGGGGGCAGGGCTCCCCCTCGGTACTGCGGTTGCACAGAGTATTTCGCCTAAACCAAGAAATTTTTTATTACCAAAA
AGAAAAAAGAAAAAAAAAATCCCAGCGGCCACCTTTCCTCCCTGCCCCATTGGGACAGTCGAGACTGGATCTGTGGGGTTTCCCGGGAGG
GTGGCTCAGGGCTGGAACACTCTCAGGCAAGAGTGGTGGAGCTCCCGTCAGGCCCTCCGCCAGGCCCACTGTGGGCTTCTCCCCTCTCCT
CCCTCCTTCCCCTCCAAGCAAACCACCAGAGGTGGCCTTCCCCTGACCTCAGGCCCCTGGGCTGGAGGCCTGGGCGGTGGGGCAGGGGGC
GGGGGTGCTGCGCAGCCCTGCAGTGGGTGGGGCTGGGGGCTGCTCCGGGGCTGCTGAGGCTGGAGGGCCGGCACAAGGCTCCGCCTCCCT
CCACACTGTACCCTCTGCCCCTCCTCCCCAGAGCTGGGCATTTCCTTCCACAAGCTGCTGTGGGGACGTGTGTTCCCTCAAAGTCTGTGC
CATCTTCTCCCACCCCTCCCGGGTAGAAGGAGGGGCTGACCCCAGGGCTGGGAGAGGGGAGGGGACTGGAGGGCAGACTGGCTTCTCGGT
CCCCAGGGGGCCGCTTGGGCTGTTGGTCTCCAGAGCAGGGCCACTGGGCACTCTGTGATGGGGGAGCCTTTGTCTGAAAGCACAGCCCCC
TCGCCCTTCCTCTCCCCATGGCTTCCCCTTCATTGGCATTAATCTGGGCACCAGCTCTCTCCATAGCAGTGACTTCCCTCACCACTCTCA
TCTCTCAGCCTTGCCTTTTCTTCCTGACACTGTCGCCCCCTCCTCTCAGGAGACACTGCCGAGGGCCACCTGGCAGAAGGCTGAGTTAGG
CAGCAGGGCCGGGAGCGTCTGCCCTCCACAGGGTGGGGGACAGATAGGCTAAGCGACTCCCAGCTTGCTACCCTCAGTGGCCAGTGTGGG
CGTGGGCGGTTTGGGGCGCTTGGCTGGTGGTGGCCACTGCATCCCTTAATTTATTTCTCTGCTGTTTCTGTTCTTGAGAAATTGGGGGTG
GGAGTCCTACACAGAGGCTGCCCCTACCCTCACCTGAGTTGTACATTTTTTTGTGATGGGTTTTATTTTTTATTATTTTATTTTATTTTT
TTTTTTTTTGATTTATGATGACTCCACCCCTCTTCATCACCCCCGCTCCCAGGCCAGGCTCAGCGATTAAGCCGAGCCCTTGCGTCCTAG
GAAGGGGCCTTGCCAACCTCAGCCCTCCTGCCCCACACTCCTACTGCGGCTCAGACCAAGGGCTCCCCCTCCCTCCCTTCCCCCCTCCTG
CCCTATGGAACAGCCCGGGTGCTCTGAGGGGGCTGGGAGGGCATGGCTTGGCTCCCAAAGGGGGTAGGGGCCCGGGGCACCCAGGCAAGG
TGGCCCCTCCCCGTCTAGCCCCCTCCTCCCCAACCCTGCACTTAGTTTCTCCTCTGGATCAAACACGTAATAAAGAGAATGTTTGGAATC

>In-frame_PPFIA1_ENST00000389547_chr11_70118542_+_MARK2_ENST00000377809_chr11_63662631_+_4512nt
GCTCCTCCTCCGCTCCGCCAGTGTCCGGCCGCGGGCCGGCCTTAGTGACTGGGGCGGCGGGCCCCGGGGCCGCGGCGTGGGGCGGGCAGG
CGGACGCCGGCCGCGGGCTGCTTTCGTCGGCTCCCAAGCTCTCCCGGAGCGAGCAGCCGCCCGCGAGCCGCCGCGGAGCCTCCTCGCCCG
CTCCCGCCGGCGAGCAAGATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAGGTGGAGGCCATGGTTCC
GGCTCCCCTTCACAGCCAGATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACCGCCTTCTTGATACACTG
AGAGAGACTCAAGAAACGCTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGCAGAGACAGCTCAACACG
GCACTTCCACAGCCCACCTTGGGACACCTTGACTCCAAGCCCAGCAGTAAGTCCAACATGATTCGGGGCCGCAACTCAGCCACCTCTGCT
GATGAGCAGCCCCACATTGGAAACTACCGGCTCCTCAAGACCATTGGCAAGGGTAATTTTGCCAAGGTGAAGTTGGCCCGACACATCCTG
ACTGGGAAAGAGGTAGCTGTGAAGATCATTGACAAGACTCAACTGAACTCCTCCAGCCTCCAGAAACTATTCCGCGAAGTAAGAATAATG
AAGGTTTTGAATCATCCCAACATAGTTAAATTATTTGAAGTGATTGAGACTGAGAAAACGCTCTACCTTGTCATGGAGTACGCTAGTGGC
GGAGAGGTATTTGATTACCTAGTGGCTCATGGCAGGATGAAAGAAAAAGAGGCTCGAGCCAAATTCCGCCAGATAGTGTCTGCTGTGCAG
TACTGTCACCAGAAGTTTATTGTCCATAGAGACTTAAAGGCAGAAAACCTGCTCTTGGATGCTGATATGAACATCAAGATTGCAGACTTT
GGCTTCAGCAATGAATTCACCTTTGGGAACAAGCTGGACACCTTCTGTGGCAGTCCCCCTTATGCTGCCCCAGAACTCTTCCAGGGCAAA
AAATATGATGGACCCGAGGTGGATGTGTGGAGCCTAGGAGTTATCCTCTATACACTGGTCAGCGGATCCCTGCCTTTTGATGGACAGAAC
CTCAAGGAGCTGCGGGAACGGGTACTGAGGGGAAAATACCGTATTCCATTCTACATGTCCACGGACTGTGAAAACCTGCTTAAGAAATTT
CTCATTCTTAATCCCAGCAAGAGAGGCACTTTAGAGCAAATCATGAAAGATCGATGGATGAATGTGGGTCACGAAGATGATGAACTAAAG
CCTTACGTGGAGCCACTCCCTGACTACAAGGACCCCCGGCGGACAGAGCTGATGGTGTCCATGGGTTATACACGGGAAGAGATCCAGGAC
TCGCTGGTGGGCCAGAGATACAACGAGGTGATGGCCACCTATCTGCTCCTGGGCTACAAGAGCTCCGAGCTGGAAGGCGACACCATCACC
CTGAAACCCCGGCCTTCAGCTGATCTGACCAATAGCAGCGCCCCATCCCCATCCCACAAGGTACAGCGCAGCGTGTCGGCCAATCCCAAG
CAGCGGCGCTTCAGCGACCAGGCAGCTGGTCCTGCCATTCCCACCTCTAATTCTTACTCTAAGAAGACTCAGAGTAACAACGCAGAAAAT
AAGCGGCCTGAGGAGGACCGGGAGTCAGGGCGGAAAGCCAGCAGCACAGCCAAGGTGCCTGCCAGCCCCCTGCCCGGTCTGGAGAGGAAG
AAGACCACCCCAACCCCCTCCACGAACAGCGTCCTCTCCACCAGCACAAATCGAAGCAGGAATTCCCCACTTTTGGAGCGGGCCAGCCTC
GGCCAGGCCTCCATCCAGAATGGCAAAGACAGCCTAACCATGCCAGGGTCCCGGGCCTCCACGGCTTCTGCTTCTGCCGCAGTCTCTGCG
GCCCGGCCCCGCCAGCACCAGAAATCCATGTCGGCCTCCGTGCACCCCAACAAGGCCTCTGGGCTGCCCCCCACGGAGAGTAACTGTGAG
GTGCCGCGGCCCAGCACAGCCCCCCAGCGTGTCCCTGTTGCCTCCCCATCCGCCCACAACATCAGCAGCAGTGGTGGAGCCCCAGACCGA
ACTAACTTCCCCCGGGGTGTGTCCAGCCGAAGCACCTTCCATGCTGGGCAGCTCCGACAGGTGCGGGACCAGCAGAATTTGCCCTACGGT
GTGACCCCAGCCTCTCCCTCTGGCCACAGCCAGGGCCGGCGGGGGGCCTCTGGGAGCATCTTCAGCAAGTTCACCTCCAAGTTTGTACGC
AGAAATCTGTCTTTCAGGTTTGCCAGAAGACCTCACGTGGTGGGCAGTGGCGGCAACGACAAAGAAAAGGAAGAATTTCGGGAGGCCAAG
CCCCGCTCCCTCCGCTTCACGTGGAGTATGAAGACCACGAGCTCCATGGAGCCCAACGAGATGATGCGGGAGATCCGCAAGGTGCTGGAC
GCGAACAGCTGCCAGAGCGAGCTGCATGAGAAGTACATGCTGCTGTGCATGCACGGCACGCCGGGCCACGAGGACTTCGTGCAGTGGGAG
ATGGAGGTGTGCAAACTGCCGCGGCTCTCTCTCAACGGGGTTCGATTTAAGCGGATATCGGGCACCTCCATGGCCTTCAAAAACATTGCC
TCCAAAATAGCCAACGAGCTGAAGCTTTAACAGGCTGCCAGGAGCGGGGGCGGCGGGGGCGGGCCAGCTGGACGGGCTGCCGGCCGCTGC
GCCGCCCCACCTGGGCGAGACTGCAGCGATGGATTGGTGTGTCTCCCCTGCTGGCACTTCTCCCCTCCCTGGCCCTTCTCAGTTTTCTCT
TACATGTTTGTGGGGGGTGGGAGATTGTTCTCCAGCACCCCACATTCACCCCTGCCCAGAGATTCCCCCTTCTCCTCTCCCCTACTGGAG
GCAAAGGAAGGGGAGGGTGGATGGGGGGGCAGGGCTCCCCCTCGGTACTGCGGTTGCACAGAGTATTTCGCCTAAACCAAGAAATTTTTT
ATTACCAAAAAGAAAAAAGAAAAAAAAAATCCCAGCGGCCACCTTTCCTCCCTGCCCCATTGGGACAGTCGAGACTGGATCTGTGGGGTT
TCCCGGGAGGGTGGCTCAGGGCTGGAACACTCTCAGGCAAGAGTGGTGGAGCTCCCGTCAGGCCCTCCGCCAGGCCCACTGTGGGCTTCT
CCCCTCTCCTCCCTCCTTCCCCTCCAAGCAAACCACCAGAGGTGGCCTTCCCCTGACCTCAGGCCCCTGGGCTGGAGGCCTGGGCGGTGG
GGCAGGGGGCGGGGGTGCTGCGCAGCCCTGCAGTGGGTGGGGCTGGGGGCTGCTCCGGGGCTGCTGAGGCTGGAGGGCCGGCACAAGGCT
CCGCCTCCCTCCACACTGTACCCTCTGCCCCTCCTCCCCAGAGCTGGGCATTTCCTTCCACAAGCTGCTGTGGGGACGTGTGTTCCCTCA
AAGTCTGTGCCATCTTCTCCCACCCCTCCCGGGTAGAAGGAGGGGCTGACCCCAGGGCTGGGAGAGGGGAGGGGACTGGAGGGCAGACTG
GCTTCTCGGTCCCCAGGGGGCCGCTTGGGCTGTTGGTCTCCAGAGCAGGGCCACTGGGCACTCTGTGATGGGGGAGCCTTTGTCTGAAAG
CACAGCCCCCTCGCCCTTCCTCTCCCCATGGCTTCCCCTTCATTGGCATTAATCTGGGCACCAGCTCTCTCCATAGCAGTGACTTCCCTC
ACCACTCTCATCTCTCAGCCTTGCCTTTTCTTCCTGACACTGTCGCCCCCTCCTCTCAGGAGACACTGCCGAGGGCCACCTGGCAGAAGG
CTGAGTTAGGCAGCAGGGCCGGGAGCGTCTGCCCTCCACAGGGTGGGGGACAGATAGGCTAAGCGACTCCCAGCTTGCTACCCTCAGTGG
CCAGTGTGGGCGTGGGCGGTTTGGGGCGCTTGGCTGGTGGTGGCCACTGCATCCCTTAATTTATTTCTCTGCTGTTTCTGTTCTTGAGAA
ATTGGGGGTGGGAGTCCTACACAGAGGCTGCCCCTACCCTCACCTGAGTTGTACATTTTTTTGTGATGGGTTTTATTTTTTATTATTTTA
TTTTATTTTTTTTTTTTTTGATTTATGATGACTCCACCCCTCTTCATCACCCCCGCTCCCAGGCCAGGCTCAGCGATTAAGCCGAGCCCT
TGCGTCCTAGGAAGGGGCCTTGCCAACCTCAGCCCTCCTGCCCCACACTCCTACTGCGGCTCAGACCAAGGGCTCCCCCTCCCTCCCTTC
CCCCCTCCTGCCCTATGGAACAGCCCGGGTGCTCTGAGGGGGCTGGGAGGGCATGGCTTGGCTCCCAAAGGGGGTAGGGGCCCGGGGCAC
CCAGGCAAGGTGGCCCCTCCCCGTCTAGCCCCCTCCTCCCCAACCCTGCACTTAGTTTCTCCTCTGGATCAAACACGTAATAAAGAGAAT

>In-frame_PPFIA1_ENST00000389547_chr11_70118542_+_MARK2_ENST00000402010_chr11_63662631_+_4557nt
GCTCCTCCTCCGCTCCGCCAGTGTCCGGCCGCGGGCCGGCCTTAGTGACTGGGGCGGCGGGCCCCGGGGCCGCGGCGTGGGGCGGGCAGG
CGGACGCCGGCCGCGGGCTGCTTTCGTCGGCTCCCAAGCTCTCCCGGAGCGAGCAGCCGCCCGCGAGCCGCCGCGGAGCCTCCTCGCCCG
CTCCCGCCGGCGAGCAAGATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAGGTGGAGGCCATGGTTCC
GGCTCCCCTTCACAGCCAGATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACCGCCTTCTTGATACACTG
AGAGAGACTCAAGAAACGCTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGCAGAGACAGCTCAACACG
GCACTTCCACAGCCCACCTTGGGACACCTTGACTCCAAGCCCAGCAGTAAGTCCAACATGATTCGGGGCCGCAACTCAGCCACCTCTGCT
GATGAGCAGCCCCACATTGGAAACTACCGGCTCCTCAAGACCATTGGCAAGGGTAATTTTGCCAAGGTGAAGTTGGCCCGACACATCCTG
ACTGGGAAAGAGGTAGCTGTGAAGATCATTGACAAGACTCAACTGAACTCCTCCAGCCTCCAGAAACTATTCCGCGAAGTAAGAATAATG
AAGGTTTTGAATCATCCCAACATAGTTAAATTATTTGAAGTGATTGAGACTGAGAAAACGCTCTACCTTGTCATGGAGTACGCTAGTGGC
GGAGAGGTATTTGATTACCTAGTGGCTCATGGCAGGATGAAAGAAAAAGAGGCTCGAGCCAAATTCCGCCAGATAGTGTCTGCTGTGCAG
TACTGTCACCAGAAGTTTATTGTCCATAGAGACTTAAAGGCAGAAAACCTGCTCTTGGATGCTGATATGAACATCAAGATTGCAGACTTT
GGCTTCAGCAATGAATTCACCTTTGGGAACAAGCTGGACACCTTCTGTGGCAGTCCCCCTTATGCTGCCCCAGAACTCTTCCAGGGCAAA
AAATATGATGGACCCGAGGTGGATGTGTGGAGCCTAGGAGTTATCCTCTATACACTGGTCAGCGGATCCCTGCCTTTTGATGGACAGAAC
CTCAAGGAGCTGCGGGAACGGGTACTGAGGGGAAAATACCGTATTCCATTCTACATGTCCACGGACTGTGAAAACCTGCTTAAGAAATTT
CTCATTCTTAATCCCAGCAAGAGAGGCACTTTAGAGCAAATCATGAAAGATCGATGGATGAATGTGGGTCACGAAGATGATGAACTAAAG
CCTTACGTGGAGCCACTCCCTGACTACAAGGACCCCCGGCGGACAGAGCTGATGGTGTCCATGGGTTATACACGGGAAGAGATCCAGGAC
TCGCTGGTGGGCCAGAGATACAACGAGGTGATGGCCACCTATCTGCTCCTGGGCTACAAGAGCTCCGAGCTGGAAGGCGACACCATCACC
CTGAAACCCCGGCCTTCAGCTGATCTGACCAATAGCAGCGCCCCATCCCCATCCCACAAGGTACAGCGCAGCGTGTCGGCCAATCCCAAG
CAGCGGCGCTTCAGCGACCAGGCAGCTGGTCCTGCCATTCCCACCTCTAATTCTTACTCTAAGAAGACTCAGAGTAACAACGCAGAAAAT
AAGCGGCCTGAGGAGGACCGGGAGTCAGGGCGGAAAGCCAGCAGCACAGCCAAGGTGCCTGCCAGCCCCCTGCCCGGTCTGGAGAGGAAG
AAGACCACCCCAACCCCCTCCACGAACAGCGTCCTCTCCACCAGCACAAATCGAAGCAGGAATTCCCCACTTTTGGAGCGGGCCAGCCTC
GGCCAGGCCTCCATCCAGAATGGCAAAGACAGCCTAACCATGCCAGGGTCCCGGGCCTCCACGGCTTCTGCTTCTGCCGCAGTCTCTGCG
GCCCGGCCCCGCCAGCACCAGAAATCCATGTCGGCCTCCGTGCACCCCAACAAGGCCTCTGGGCTGCCCCCCACGGAGAGTAACTGTGAG
GTGCCGCGGCCCAGCACAGCCCCCCAGCGTGTCCCTGTTGCCTCCCCATCCGCCCACAACATCAGCAGCAGTGGTGGAGCCCCAGACCGA
ACTAACTTCCCCCGGGGTGTGTCCAGCCGAAGCACCTTCCATGCTGGGCAGCTCCGACAGGTGCGGGACCAGCAGAATTTGCCCTACGGT
GTGACCCCAGCCTCTCCCTCTGGCCACAGCCAGGGCCGGCGGGGGGCCTCTGGGAGCATCTTCAGCAAGTTCACCTCCAAGTTTGTACGC
AGAAATCTGTCTTTCAGGTTTGCCAGAAGGAACCTGAATGAACCTGAAAGCAAAGACCGAGTGGAGACGCTCAGACCTCACGTGGTGGGC
AGTGGCGGCAACGACAAAGAAAAGGAAGAATTTCGGGAGGCCAAGCCCCGCTCCCTCCGCTTCACGTGGAGTATGAAGACCACGAGCTCC
ATGGAGCCCAACGAGATGATGCGGGAGATCCGCAAGGTGCTGGACGCGAACAGCTGCCAGAGCGAGCTGCATGAGAAGTACATGCTGCTG
TGCATGCACGGCACGCCGGGCCACGAGGACTTCGTGCAGTGGGAGATGGAGGTGTGCAAACTGCCGCGGCTCTCTCTCAACGGGGTTCGA
TTTAAGCGGATATCGGGCACCTCCATGGCCTTCAAAAACATTGCCTCCAAAATAGCCAACGAGCTGAAGCTTTAACAGGCTGCCAGGAGC
GGGGGCGGCGGGGGCGGGCCAGCTGGACGGGCTGCCGGCCGCTGCGCCGCCCCACCTGGGCGAGACTGCAGCGATGGATTGGTGTGTCTC
CCCTGCTGGCACTTCTCCCCTCCCTGGCCCTTCTCAGTTTTCTCTTACATGTTTGTGGGGGGTGGGAGATTGTTCTCCAGCACCCCACAT
TCACCCCTGCCCAGAGATTCCCCCTTCTCCTCTCCCCTACTGGAGGCAAAGGAAGGGGAGGGTGGATGGGGGGGCAGGGCTCCCCCTCGG
TACTGCGGTTGCACAGAGTATTTCGCCTAAACCAAGAAATTTTTTATTACCAAAAAGAAAAAAGAAAAAAAAAATCCCAGCGGCCACCTT
TCCTCCCTGCCCCATTGGGACAGTCGAGACTGGATCTGTGGGGTTTCCCGGGAGGGTGGCTCAGGGCTGGAACACTCTCAGGCAAGAGTG
GTGGAGCTCCCGTCAGGCCCTCCGCCAGGCCCACTGTGGGCTTCTCCCCTCTCCTCCCTCCTTCCCCTCCAAGCAAACCACCAGAGGTGG
CCTTCCCCTGACCTCAGGCCCCTGGGCTGGAGGCCTGGGCGGTGGGGCAGGGGGCGGGGGTGCTGCGCAGCCCTGCAGTGGGTGGGGCTG
GGGGCTGCTCCGGGGCTGCTGAGGCTGGAGGGCCGGCACAAGGCTCCGCCTCCCTCCACACTGTACCCTCTGCCCCTCCTCCCCAGAGCT
GGGCATTTCCTTCCACAAGCTGCTGTGGGGACGTGTGTTCCCTCAAAGTCTGTGCCATCTTCTCCCACCCCTCCCGGGTAGAAGGAGGGG
CTGACCCCAGGGCTGGGAGAGGGGAGGGGACTGGAGGGCAGACTGGCTTCTCGGTCCCCAGGGGGCCGCTTGGGCTGTTGGTCTCCAGAG
CAGGGCCACTGGGCACTCTGTGATGGGGGAGCCTTTGTCTGAAAGCACAGCCCCCTCGCCCTTCCTCTCCCCATGGCTTCCCCTTCATTG
GCATTAATCTGGGCACCAGCTCTCTCCATAGCAGTGACTTCCCTCACCACTCTCATCTCTCAGCCTTGCCTTTTCTTCCTGACACTGTCG
CCCCCTCCTCTCAGGAGACACTGCCGAGGGCCACCTGGCAGAAGGCTGAGTTAGGCAGCAGGGCCGGGAGCGTCTGCCCTCCACAGGGTG
GGGGACAGATAGGCTAAGCGACTCCCAGCTTGCTACCCTCAGTGGCCAGTGTGGGCGTGGGCGGTTTGGGGCGCTTGGCTGGTGGTGGCC
ACTGCATCCCTTAATTTATTTCTCTGCTGTTTCTGTTCTTGAGAAATTGGGGGTGGGAGTCCTACACAGAGGCTGCCCCTACCCTCACCT
GAGTTGTACATTTTTTTGTGATGGGTTTTATTTTTTATTATTTTATTTTATTTTTTTTTTTTTTGATTTATGATGACTCCACCCCTCTTC
ATCACCCCCGCTCCCAGGCCAGGCTCAGCGATTAAGCCGAGCCCTTGCGTCCTAGGAAGGGGCCTTGCCAACCTCAGCCCTCCTGCCCCA
CACTCCTACTGCGGCTCAGACCAAGGGCTCCCCCTCCCTCCCTTCCCCCCTCCTGCCCTATGGAACAGCCCGGGTGCTCTGAGGGGGCTG
GGAGGGCATGGCTTGGCTCCCAAAGGGGGTAGGGGCCCGGGGCACCCAGGCAAGGTGGCCCCTCCCCGTCTAGCCCCCTCCTCCCCAACC

>In-frame_PPFIA1_ENST00000389547_chr11_70118542_+_MARK2_ENST00000413835_chr11_63662631_+_4395nt
GCTCCTCCTCCGCTCCGCCAGTGTCCGGCCGCGGGCCGGCCTTAGTGACTGGGGCGGCGGGCCCCGGGGCCGCGGCGTGGGGCGGGCAGG
CGGACGCCGGCCGCGGGCTGCTTTCGTCGGCTCCCAAGCTCTCCCGGAGCGAGCAGCCGCCCGCGAGCCGCCGCGGAGCCTCCTCGCCCG
CTCCCGCCGGCGAGCAAGATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAGGTGGAGGCCATGGTTCC
GGCTCCCCTTCACAGCCAGATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACCGCCTTCTTGATACACTG
AGAGAGACTCAAGAAACGCTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGCAGAGACAGCTCAACACG
GCACTTCCACAGCCCACCTTGGGACACCTTGACTCCAAGCCCAGCAGTAAGTCCAACATGATTCGGGGCCGCAACTCAGCCACCTCTGCT
GATGAGCAGCCCCACATTGGAAACTACCGGCTCCTCAAGACCATTGGCAAGGGTAATTTTGCCAAGGTGAAGTTGGCCCGACACATCCTG
ACTGGGAAAGAGGTAGCTGTGAAGATCATTGACAAGACTCAACTGAACTCCTCCAGCCTCCAGAAACTATTCCGCGAAGTAAGAATAATG
AAGGTTTTGAATCATCCCAACATAGTTAAATTATTTGAAGTGATTGAGACTGAGAAAACGCTCTACCTTGTCATGGAGTACGCTAGTGGC
GGAGAGGTATTTGATTACCTAGTGGCTCATGGCAGGATGAAAGAAAAAGAGGCTCGAGCCAAATTCCGCCAGATAGTGTCTGCTGTGCAG
TACTGTCACCAGAAGTTTATTGTCCATAGAGACTTAAAGGCAGAAAACCTGCTCTTGGATGCTGATATGAACATCAAGATTGCAGACTTT
GGCTTCAGCAATGAATTCACCTTTGGGAACAAGCTGGACACCTTCTGTGGCAGTCCCCCTTATGCTGCCCCAGAACTCTTCCAGGGCAAA
AAATATGATGGACCCGAGGTGGATGTGTGGAGCCTAGGAGTTATCCTCTATACACTGGTCAGCGGATCCCTGCCTTTTGATGGACAGAAC
CTCAAGGAGCTGCGGGAACGGGTACTGAGGGGAAAATACCGTATTCCATTCTACATGTCCACGGACTGTGAAAACCTGCTTAAGAAATTT
CTCATTCTTAATCCCAGCAAGAGAGGCACTTTAGAGCAAATCATGAAAGATCGATGGATGAATGTGGGTCACGAAGATGATGAACTAAAG
CCTTACGTGGAGCCACTCCCTGACTACAAGGACCCCCGGCGGACAGAGCTGATGGTGTCCATGGGTTATACACGGGAAGAGATCCAGGAC
TCGCTGGTGGGCCAGAGATACAACGAGGTGATGGCCACCTATCTGCTCCTGGGCTACAAGAGCTCCGAGCTGGAAGGCGACACCATCACC
CTGAAACCCCGGCCTTCAGCTGATCTGACCAATAGCAGCGCCCCATCCCCATCCCACAAGGTACAGCGCAGCGTGTCGGCCAATCCCAAG
CAGCGGCGCTTCAGCGACCAGGCAGCTGGTCCTGCCATTCCCACCTCTAATTCTTACTCTAAGAAGACTCAGAGTAACAACGCAGAAAAT
AAGCGGCCTGAGGAGGACCGGGAGTCAGGGCGGAAAGCCAGCAGCACAGCCAAGGTGCCTGCCAGCCCCCTGCCCGGTCTGGAGAGGAAG
AAGACCACCCCAACCCCCTCCACGAACAGCGTCCTCTCCACCAGCACAAATCGAAGCAGGAATTCCCCACTTTTGGAGCGGGCCAGCCTC
GGCCAGGCCTCCATCCAGAATGGCAAAGACAGCACAGCCCCCCAGCGTGTCCCTGTTGCCTCCCCATCCGCCCACAACATCAGCAGCAGT
GGTGGAGCCCCAGACCGAACTAACTTCCCCCGGGGTGTGTCCAGCCGAAGCACCTTCCATGCTGGGCAGCTCCGACAGGTGCGGGACCAG
CAGAATTTGCCCTACGGTGTGACCCCAGCCTCTCCCTCTGGCCACAGCCAGGGCCGGCGGGGGGCCTCTGGGAGCATCTTCAGCAAGTTC
ACCTCCAAGTTTGTACGCAGAAATCTGTCTTTCAGGTTTGCCAGAAGGAACCTGAATGAACCTGAAAGCAAAGACCGAGTGGAGACGCTC
AGACCTCACGTGGTGGGCAGTGGCGGCAACGACAAAGAAAAGGAAGAATTTCGGGAGGCCAAGCCCCGCTCCCTCCGCTTCACGTGGAGT
ATGAAGACCACGAGCTCCATGGAGCCCAACGAGATGATGCGGGAGATCCGCAAGGTGCTGGACGCGAACAGCTGCCAGAGCGAGCTGCAT
GAGAAGTACATGCTGCTGTGCATGCACGGCACGCCGGGCCACGAGGACTTCGTGCAGTGGGAGATGGAGGTGTGCAAACTGCCGCGGCTC
TCTCTCAACGGGGTTCGATTTAAGCGGATATCGGGCACCTCCATGGCCTTCAAAAACATTGCCTCCAAAATAGCCAACGAGCTGAAGCTT
TAACAGGCTGCCAGGAGCGGGGGCGGCGGGGGCGGGCCAGCTGGACGGGCTGCCGGCCGCTGCGCCGCCCCACCTGGGCGAGACTGCAGC
GATGGATTGGTGTGTCTCCCCTGCTGGCACTTCTCCCCTCCCTGGCCCTTCTCAGTTTTCTCTTACATGTTTGTGGGGGGTGGGAGATTG
TTCTCCAGCACCCCACATTCACCCCTGCCCAGAGATTCCCCCTTCTCCTCTCCCCTACTGGAGGCAAAGGAAGGGGAGGGTGGATGGGGG
GGCAGGGCTCCCCCTCGGTACTGCGGTTGCACAGAGTATTTCGCCTAAACCAAGAAATTTTTTATTACCAAAAAGAAAAAAGAAAAAAAA
AATCCCAGCGGCCACCTTTCCTCCCTGCCCCATTGGGACAGTCGAGACTGGATCTGTGGGGTTTCCCGGGAGGGTGGCTCAGGGCTGGAA
CACTCTCAGGCAAGAGTGGTGGAGCTCCCGTCAGGCCCTCCGCCAGGCCCACTGTGGGCTTCTCCCCTCTCCTCCCTCCTTCCCCTCCAA
GCAAACCACCAGAGGTGGCCTTCCCCTGACCTCAGGCCCCTGGGCTGGAGGCCTGGGCGGTGGGGCAGGGGGCGGGGGTGCTGCGCAGCC
CTGCAGTGGGTGGGGCTGGGGGCTGCTCCGGGGCTGCTGAGGCTGGAGGGCCGGCACAAGGCTCCGCCTCCCTCCACACTGTACCCTCTG
CCCCTCCTCCCCAGAGCTGGGCATTTCCTTCCACAAGCTGCTGTGGGGACGTGTGTTCCCTCAAAGTCTGTGCCATCTTCTCCCACCCCT
CCCGGGTAGAAGGAGGGGCTGACCCCAGGGCTGGGAGAGGGGAGGGGACTGGAGGGCAGACTGGCTTCTCGGTCCCCAGGGGGCCGCTTG
GGCTGTTGGTCTCCAGAGCAGGGCCACTGGGCACTCTGTGATGGGGGAGCCTTTGTCTGAAAGCACAGCCCCCTCGCCCTTCCTCTCCCC
ATGGCTTCCCCTTCATTGGCATTAATCTGGGCACCAGCTCTCTCCATAGCAGTGACTTCCCTCACCACTCTCATCTCTCAGCCTTGCCTT
TTCTTCCTGACACTGTCGCCCCCTCCTCTCAGGAGACACTGCCGAGGGCCACCTGGCAGAAGGCTGAGTTAGGCAGCAGGGCCGGGAGCG
TCTGCCCTCCACAGGGTGGGGGACAGATAGGCTAAGCGACTCCCAGCTTGCTACCCTCAGTGGCCAGTGTGGGCGTGGGCGGTTTGGGGC
GCTTGGCTGGTGGTGGCCACTGCATCCCTTAATTTATTTCTCTGCTGTTTCTGTTCTTGAGAAATTGGGGGTGGGAGTCCTACACAGAGG
CTGCCCCTACCCTCACCTGAGTTGTACATTTTTTTGTGATGGGTTTTATTTTTTATTATTTTATTTTATTTTTTTTTTTTTTGATTTATG
ATGACTCCACCCCTCTTCATCACCCCCGCTCCCAGGCCAGGCTCAGCGATTAAGCCGAGCCCTTGCGTCCTAGGAAGGGGCCTTGCCAAC
CTCAGCCCTCCTGCCCCACACTCCTACTGCGGCTCAGACCAAGGGCTCCCCCTCCCTCCCTTCCCCCCTCCTGCCCTATGGAACAGCCCG
GGTGCTCTGAGGGGGCTGGGAGGGCATGGCTTGGCTCCCAAAGGGGGTAGGGGCCCGGGGCACCCAGGCAAGGTGGCCCCTCCCCGTCTA


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FusionGenePPI for PPFIA1_MARK2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
PPFIA1GIT1, ERC2, PPP2R5D, TNNT1, MBIP, GRIP2, PTPRF, PTPRD, PTPRS, NCOA2, PPP2CA, PPP2R1A, PPFIA1, PPFIA2, ING4, PPP2CB, CUL2, AGTPBP1, CEP70, AMOT, LATS2, YWHAB, IKBKG, PSMC4, PSMD1, PSMD13, PSMD8, SPTAN1, DROSHA, NDN, AURKB, CDKN1A, CCNH, DTNB, FAM161A, TXLNA, BRCA1, GPS2, C16orf70, CYP4X1, NTRK1, OSBP, PPFIA3, PPFIBP1, PPFIBP2, CAGE1, TUBG1, XRCC1, GBA2, CDC5L, NF2, IL17RE, LLGL2, SERPINB2, STX11, EXOC8, TTC9B, CCDC120, TRIM25MARK2YWHAG, YWHAQ, MAP3K3, SFN, AKT1, DTNA, USP21, FUCA1, KIF5B, MARK1, MARK3, PRKCI, SNTB2, UTRN, YWHAH, ARHGEF2, GPRASP1, COL4A3BP, C11orf58, CLASP2, PMPCA, PHLPP1, MTCL1, KIF13B, UTP18, MARK4, CEP85L, HDAC7, TADA2A, PRKAA1, NEDD4, PARD6A, YWHAZ, PARD6G, MARK2, NEDD4L, STK11, YWHAE, RAB11FIP2, PPP2R4, YWHAB, DMD, RHOA, PINK1, PRKCE, PKD1, VCP, GAB1, GAB2, PARD3, RNF41, CAMK1, AURKB, CDKN1A, CEP57, MAPT, BAIAP2, CCDC8, NAP1L5, CDK15, HNRNPA1, NTRK1, CEP89, DCTN1, TMEM17, CAPZA1, CAPZA2, CAPZB, AP2M1, APC, LDHD, PPP2R1A, PPP2R5E, HERC2, DLG5, WDR46, PDCD7, PRDX3, NUPL2, CAMSAP2, CLASP1, RSF1, CCDC82, SOGA1, FBXL16, FRYL, CDC5L, SMURF1, CDH1, TMCC2, NRROS, NUAK2, SIX2, MANSC1, CDH19, CAV3, CBY1


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for PPFIA1_MARK2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for PPFIA1_MARK2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneMARK2C0036341Schizophrenia2PSYGENET
TgeneMARK2C0010606Adenoid Cystic Carcinoma1CTD_human
TgeneMARK2C0036095Salivary Gland Neoplasms1CTD_human