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Fusion gene ID: 28008 |
FusionGeneSummary for POLR3K_L3MBTL4 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: POLR3K_L3MBTL4 | Fusion gene ID: 28008 | Hgene | Tgene | Gene symbol | POLR3K | L3MBTL4 | Gene ID | 51728 | 91133 |
| Gene name | RNA polymerase III subunit K | L3MBTL4, histone methyl-lysine binding protein | |
| Synonyms | C11|C11-RNP3|My010|RPC10|RPC11|RPC12.5 | HsT1031 | |
| Cytomap | 16p13.3 | 18p11.31 | |
| Type of gene | protein-coding | protein-coding | |
| Description | DNA-directed RNA polymerase III subunit RPC10DNA-directed RNA polymerase III subunit KDNA-directed RNA polymerases III 12.5 kDa polypeptideRNA polymerase III 12.5 kDa subunitRNA polymerase III subunit C10RNA polymerase III subunit C11RNA polymerase | lethal(3)malignant brain tumor-like protein 4H-l(3)mbt-like protein 4L3mbt-like 4l(3)mbt-like 4l(3)mbt-like protein 4 | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q9Y2Y1 | Q8NA19 | |
| Ensembl transtripts involved in fusion gene | ENST00000293860, | ENST00000400105, ENST00000317931, ENST00000284898, ENST00000400104, ENST00000535782, ENST00000578677, | |
| Fusion gene scores | * DoF score | 3 X 3 X 3=27 | 10 X 8 X 5=400 |
| # samples | 3 | 10 | |
| ** MAII score | log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(10/400*10)=-2 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: POLR3K [Title/Abstract] AND L3MBTL4 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. Tumor suppressor gene involved fusion gene, retained protein feature but frameshift. DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-A8-A079-01A | POLR3K | chr16 | 101558 | - | L3MBTL4 | chr18 | 6215834 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000293860 | ENST00000400105 | POLR3K | chr16 | 101558 | - | L3MBTL4 | chr18 | 6215834 | - |
| In-frame | ENST00000293860 | ENST00000317931 | POLR3K | chr16 | 101558 | - | L3MBTL4 | chr18 | 6215834 | - |
| In-frame | ENST00000293860 | ENST00000284898 | POLR3K | chr16 | 101558 | - | L3MBTL4 | chr18 | 6215834 | - |
| In-frame | ENST00000293860 | ENST00000400104 | POLR3K | chr16 | 101558 | - | L3MBTL4 | chr18 | 6215834 | - |
| In-frame | ENST00000293860 | ENST00000535782 | POLR3K | chr16 | 101558 | - | L3MBTL4 | chr18 | 6215834 | - |
| 5CDS-intron | ENST00000293860 | ENST00000578677 | POLR3K | chr16 | 101558 | - | L3MBTL4 | chr18 | 6215834 | - |
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FusionProtFeatures for POLR3K_L3MBTL4 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| POLR3K | L3MBTL4 |
| DNA-dependent RNA polymerase catalyzes the transcriptionof DNA into RNA using the four ribonucleoside triphosphates assubstrates. Component of RNA polymerase III which synthesizessmall RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensingand limiting infection by intracellular bacteria and DNA viruses.Acts as nuclear and cytosolic DNA sensor involved in innate immuneresponse. Can sense non-self dsDNA that serves as template fortranscription into dsRNA. The non-self RNA polymerase IIItranscripts, such as Epstein-Barr virus-encoded RNAs (EBERs)induce type I interferon and NF- Kappa-B through the RIG-I pathway(By similarity). {ECO:0000250, ECO:0000269|PubMed:19609254,ECO:0000269|PubMed:19631370}. | Putative Polycomb group (PcG) protein. PcG proteinsmaintain the transcriptionally repressive state of genes, probablyvia a modification of chromatin, rendering it heritably changed inits expressibility (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | POLR3K | chr16:101558 | chr18:6215834 | ENST00000293860 | - | 2 | 3 | 5_28 | 66 | 109 | Zinc finger | C4-type |
| Tgene | >L3MBTL4 | chr16:101558 | chr18:6215834 | ENST00000284898 | - | 9 | 20 | 543_607 | 261 | 624 | Domain | SAM |
| Tgene | >L3MBTL4 | chr16:101558 | chr18:6215834 | ENST00000400104 | - | 9 | 17 | 543_607 | 261 | 535 | Domain | SAM |
| Tgene | >L3MBTL4 | chr16:101558 | chr18:6215834 | ENST00000400105 | - | 9 | 20 | 543_607 | 261 | 624 | Domain | SAM |
| Tgene | >L3MBTL4 | chr16:101558 | chr18:6215834 | ENST00000284898 | - | 9 | 20 | 269_364 | 261 | 624 | Repeat | Note=MBT 3 |
| Tgene | >L3MBTL4 | chr16:101558 | chr18:6215834 | ENST00000400104 | - | 9 | 17 | 269_364 | 261 | 535 | Repeat | Note=MBT 3 |
| Tgene | >L3MBTL4 | chr16:101558 | chr18:6215834 | ENST00000400105 | - | 9 | 20 | 269_364 | 261 | 624 | Repeat | Note=MBT 3 |
| Tgene | >L3MBTL4 | chr16:101558 | chr18:6215834 | ENST00000284898 | - | 9 | 20 | 370_414 | 261 | 624 | Zinc finger | CCHHC-type |
| Tgene | >L3MBTL4 | chr16:101558 | chr18:6215834 | ENST00000400104 | - | 9 | 17 | 370_414 | 261 | 535 | Zinc finger | CCHHC-type |
| Tgene | >L3MBTL4 | chr16:101558 | chr18:6215834 | ENST00000400105 | - | 9 | 20 | 370_414 | 261 | 624 | Zinc finger | CCHHC-type |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >POLR3K | chr16:101558 | chr18:6215834 | ENST00000293860 | - | 2 | 3 | 65_107 | 66 | 109 | Zinc finger | TFIIS-type |
| Tgene | L3MBTL4 | chr16:101558 | chr18:6215834 | ENST00000284898 | - | 9 | 20 | 160_260 | 261 | 624 | Repeat | Note=MBT 2 |
| Tgene | L3MBTL4 | chr16:101558 | chr18:6215834 | ENST00000284898 | - | 9 | 20 | 52_152 | 261 | 624 | Repeat | Note=MBT 1 |
| Tgene | L3MBTL4 | chr16:101558 | chr18:6215834 | ENST00000400104 | - | 9 | 17 | 160_260 | 261 | 535 | Repeat | Note=MBT 2 |
| Tgene | L3MBTL4 | chr16:101558 | chr18:6215834 | ENST00000400104 | - | 9 | 17 | 52_152 | 261 | 535 | Repeat | Note=MBT 1 |
| Tgene | L3MBTL4 | chr16:101558 | chr18:6215834 | ENST00000400105 | - | 9 | 20 | 160_260 | 261 | 624 | Repeat | Note=MBT 2 |
| Tgene | L3MBTL4 | chr16:101558 | chr18:6215834 | ENST00000400105 | - | 9 | 20 | 52_152 | 261 | 624 | Repeat | Note=MBT 1 |
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FusionGeneSequence for POLR3K_L3MBTL4 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_POLR3K_ENST00000293860_chr16_101558_-_L3MBTL4_ENST00000400105_chr18_6215834_-_429aa MLLFCPGCGNGLIVEEGQRCHRFSCNTCPYVHNITRKVTNRKYPKLKEVDDVLGGAAAWENVDSTAGYPNPENFSWTEYLEATQTNAVPA KVFKMRLPHGFLPNMKLEVVDKRNPRLIRVATIVDVDDQRVKVHFDGWDHKYDYWVEADSPDIHPIGWCDVTGHPLEVPQRTNDLKILPG QAVCPTPGCRGIGHIRGPRYSGHHSAFGCPYSDMNLKKEATLHDRLREQTQANLESDSSHSKSKSLCSLNFNGKHEKVNSQPRLVQQAKC LKIKGKEDIDLDNLFRVLVLHPRGLEYSVEQAQQVLHQSVSMSTVSAHPFRDLPLGREQHCKLLPGVADIRASQVARWTVDEVAEFVQSL >In-frame_POLR3K_ENST00000293860_chr16_101558_-_L3MBTL4_ENST00000317931_chr18_6215834_-_420aa MLLFCPGCGNGLIVEEGQRCHRFSCNTCPYVHNITRKVTNRKYPKLKEVDDVLGGAAAWENVDSTAGYPNPENFSWTEYLEATQTNAVPA KVFKMRLPHGFLPNMKLEVVDKRNPRLIRVATIVDVDDQRVKVHFDGWDHKYDYWVEADSPDIHPIGWCDVTGHPLEVPQRTNDLKILPG QAVCPTPGCRGIGHIRGPRYSGHHSAFGCPYSDMNLKKEATLHDRLREQTQANLESDSSHSKSKSLCSLNFNGKHEKVNSQPRLVQQAKC LKIKGKEDIDLDNLFREYSVEQAQQVLHQSVSMSTVSAHPFRDLPLGREQHCKLLPGVADIRASQVARWTVDEVAEFVQSLLGCEEHAKC >In-frame_POLR3K_ENST00000293860_chr16_101558_-_L3MBTL4_ENST00000284898_chr18_6215834_-_429aa MLLFCPGCGNGLIVEEGQRCHRFSCNTCPYVHNITRKVTNRKYPKLKEVDDVLGGAAAWENVDSTAGYPNPENFSWTEYLEATQTNAVPA KVFKMRLPHGFLPNMKLEVVDKRNPRLIRVATIVDVDDQRVKVHFDGWDHKYDYWVEADSPDIHPIGWCDVTGHPLEVPQRTNDLKILPG QAVCPTPGCRGIGHIRGPRYSGHHSAFGCPYSDMNLKKEATLHDRLREQTQANLESDSSHSKSKSLCSLNFNGKHEKVNSQPRLVQQAKC LKIKGKEDIDLDNLFRVLVLHPRGLEYSVEQAQQVLHQSVSMSTVSAHPFRDLPLGREQHCKLLPGVADIRASQVARWTVDEVAEFVQSL >In-frame_POLR3K_ENST00000293860_chr16_101558_-_L3MBTL4_ENST00000400104_chr18_6215834_-_340aa MLLFCPGCGNGLIVEEGQRCHRFSCNTCPYVHNITRKVTNRKYPKLKEVDDVLGGAAAWENVDSTAGYPNPENFSWTEYLEATQTNAVPA KVFKMRLPHGFLPNMKLEVVDKRNPRLIRVATIVDVDDQRVKVHFDGWDHKYDYWVEADSPDIHPIGWCDVTGHPLEVPQRTNDLKILPG QAVCPTPGCRGIGHIRGPRYSGHHSAFGCPYSDMNLKKEATLHDRLREQTQANLESDSSHSKSKSLCSLNFNGKHEKVNSQPRLVQQAKC >In-frame_POLR3K_ENST00000293860_chr16_101558_-_L3MBTL4_ENST00000535782_chr18_6215834_-_420aa MLLFCPGCGNGLIVEEGQRCHRFSCNTCPYVHNITRKVTNRKYPKLKEVDDVLGGAAAWENVDSTAGYPNPENFSWTEYLEATQTNAVPA KVFKMRLPHGFLPNMKLEVVDKRNPRLIRVATIVDVDDQRVKVHFDGWDHKYDYWVEADSPDIHPIGWCDVTGHPLEVPQRTNDLKILPG QAVCPTPGCRGIGHIRGPRYSGHHSAFGCPYSDMNLKKEATLHDRLREQTQANLESDSSHSKSKSLCSLNFNGKHEKVNSQPRLVQQAKC LKIKGKEDIDLDNLFREYSVEQAQQVLHQSVSMSTVSAHPFRDLPLGREQHCKLLPGVADIRASQVARWTVDEVAEFVQSLLGCEEHAKC |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_POLR3K_ENST00000293860_chr16_101558_-_L3MBTL4_ENST00000400105_chr18_6215834_-_1287nt ATGCTGCTGTTCTGCCCCGGCTGCGGGAACGGGCTGATCGTGGAGGAGGGACAACGCTGCCACCGCTTCTCCTGCAACACGTGCCCCTAC GTGCACAACATCACCCGCAAGGTAACAAATCGGAAGTACCCAAAACTGAAAGAAGTGGATGATGTGCTTGGTGGAGCAGCTGCCTGGGAG AATGTTGACTCTACTGCAGGTTATCCCAATCCAGAAAATTTTTCCTGGACAGAATACCTGGAAGCTACTCAAACCAATGCAGTTCCTGCC AAAGTTTTTAAAATGAGGTTGCCTCATGGTTTTCTGCCAAATATGAAACTTGAAGTTGTGGATAAACGGAACCCCAGGTTAATTCGTGTT GCTACGATTGTAGATGTTGATGACCAAAGAGTAAAGGTTCATTTTGATGGTTGGGACCATAAGTATGACTACTGGGTGGAGGCAGACAGC CCTGATATCCACCCGATCGGATGGTGTGATGTCACAGGGCATCCACTGGAAGTGCCACAGCGAACGAATGACCTGAAGATCCTTCCAGGT CAAGCTGTCTGTCCTACTCCCGGGTGCCGAGGAATAGGCCATATCCGTGGTCCACGTTATTCGGGACATCACAGTGCTTTTGGCTGCCCG TATTCAGACATGAACTTGAAAAAGGAGGCAACACTTCACGATCGTTTGAGAGAACAAACACAGGCAAATTTGGAATCAGACTCTTCACAT TCAAAATCAAAAAGCCTCTGTAGTTTGAACTTCAATGGAAAACATGAAAAGGTGAACAGTCAGCCCAGACTTGTACAGCAGGCAAAGTGT TTGAAAATCAAAGGAAAAGAAGATATTGACTTGGATAATCTCTTCAGAGTGCTTGTGCTGCATCCCAGAGGTTTGGAATACTCGGTGGAG CAGGCGCAGCAGGTGCTTCACCAGTCAGTGTCCATGTCCACGGTGTCAGCCCACCCTTTTCGGGACCTTCCCCTCGGCAGGGAGCAACAC TGCAAGTTGCTTCCAGGCGTGGCTGACATCCGGGCCAGCCAAGTGGCACGTTGGACTGTGGATGAGGTGGCTGAGTTTGTACAGTCTCTT CTGGGCTGTGAAGAGCATGCCAAGTGCTTTAAGAAAGAGCAGATCGATGGCAAAGCCTTCCTGCTTCTGACACAGACGGACATTGTCAAA GTGATGAAGATCAAACTGGGCCCAGCACTGAAGATTTACAACTCTATCCTGATGTTCAGGCATTCCCAGGAACTCCCTGAAGAAGATATT >In-frame_POLR3K_ENST00000293860_chr16_101558_-_L3MBTL4_ENST00000317931_chr18_6215834_-_1260nt ATGCTGCTGTTCTGCCCCGGCTGCGGGAACGGGCTGATCGTGGAGGAGGGACAACGCTGCCACCGCTTCTCCTGCAACACGTGCCCCTAC GTGCACAACATCACCCGCAAGGTAACAAATCGGAAGTACCCAAAACTGAAAGAAGTGGATGATGTGCTTGGTGGAGCAGCTGCCTGGGAG AATGTTGACTCTACTGCAGGTTATCCCAATCCAGAAAATTTTTCCTGGACAGAATACCTGGAAGCTACTCAAACCAATGCAGTTCCTGCC AAAGTTTTTAAAATGAGGTTGCCTCATGGTTTTCTGCCAAATATGAAACTTGAAGTTGTGGATAAACGGAACCCCAGGTTAATTCGTGTT GCTACGATTGTAGATGTTGATGACCAAAGAGTAAAGGTTCATTTTGATGGTTGGGACCATAAGTATGACTACTGGGTGGAGGCAGACAGC CCTGATATCCACCCGATCGGATGGTGTGATGTCACAGGGCATCCACTGGAAGTGCCACAGCGAACGAATGACCTGAAGATCCTTCCAGGT CAAGCTGTCTGTCCTACTCCCGGGTGCCGAGGAATAGGCCATATCCGTGGTCCACGTTATTCGGGACATCACAGTGCTTTTGGCTGCCCG TATTCAGACATGAACTTGAAAAAGGAGGCAACACTTCACGATCGTTTGAGAGAACAAACACAGGCAAATTTGGAATCAGACTCTTCACAT TCAAAATCAAAAAGCCTCTGTAGTTTGAACTTCAATGGAAAACATGAAAAGGTGAACAGTCAGCCCAGACTTGTACAGCAGGCAAAGTGT TTGAAAATCAAAGGAAAAGAAGATATTGACTTGGATAATCTCTTCAGAGAATACTCGGTGGAGCAGGCGCAGCAGGTGCTTCACCAGTCA GTGTCCATGTCCACGGTGTCAGCCCACCCTTTTCGGGACCTTCCCCTCGGCAGGGAGCAACACTGCAAGTTGCTTCCAGGCGTGGCTGAC ATCCGGGCCAGCCAAGTGGCACGTTGGACTGTGGATGAGGTGGCTGAGTTTGTACAGTCTCTTCTGGGCTGTGAAGAGCATGCCAAGTGC TTTAAGAAAGAGCAGATCGATGGCAAAGCCTTCCTGCTTCTGACACAGACGGACATTGTCAAAGTGATGAAGATCAAACTGGGCCCAGCA CTGAAGATTTACAACTCTATCCTGATGTTCAGGCATTCCCAGGAACTCCCTGAAGAAGATATTGCCTCAGGCCAAGAAGTCAGGGGATGA >In-frame_POLR3K_ENST00000293860_chr16_101558_-_L3MBTL4_ENST00000284898_chr18_6215834_-_1287nt ATGCTGCTGTTCTGCCCCGGCTGCGGGAACGGGCTGATCGTGGAGGAGGGACAACGCTGCCACCGCTTCTCCTGCAACACGTGCCCCTAC GTGCACAACATCACCCGCAAGGTAACAAATCGGAAGTACCCAAAACTGAAAGAAGTGGATGATGTGCTTGGTGGAGCAGCTGCCTGGGAG AATGTTGACTCTACTGCAGGTTATCCCAATCCAGAAAATTTTTCCTGGACAGAATACCTGGAAGCTACTCAAACCAATGCAGTTCCTGCC AAAGTTTTTAAAATGAGGTTGCCTCATGGTTTTCTGCCAAATATGAAACTTGAAGTTGTGGATAAACGGAACCCCAGGTTAATTCGTGTT GCTACGATTGTAGATGTTGATGACCAAAGAGTAAAGGTTCATTTTGATGGTTGGGACCATAAGTATGACTACTGGGTGGAGGCAGACAGC CCTGATATCCACCCGATCGGATGGTGTGATGTCACAGGGCATCCACTGGAAGTGCCACAGCGAACGAATGACCTGAAGATCCTTCCAGGT CAAGCTGTCTGTCCTACTCCCGGGTGCCGAGGAATAGGCCATATCCGTGGTCCACGTTATTCGGGACATCACAGTGCTTTTGGCTGCCCG TATTCAGACATGAACTTGAAAAAGGAGGCAACACTTCACGATCGTTTGAGAGAACAAACACAGGCAAATTTGGAATCAGACTCTTCACAT TCAAAATCAAAAAGCCTCTGTAGTTTGAACTTCAATGGAAAACATGAAAAGGTGAACAGTCAGCCCAGACTTGTACAGCAGGCAAAGTGT TTGAAAATCAAAGGAAAAGAAGATATTGACTTGGATAATCTCTTCAGAGTGCTTGTGCTGCATCCCAGAGGTTTGGAATACTCGGTGGAG CAGGCGCAGCAGGTGCTTCACCAGTCAGTGTCCATGTCCACGGTGTCAGCCCACCCTTTTCGGGACCTTCCCCTCGGCAGGGAGCAACAC TGCAAGTTGCTTCCAGGCGTGGCTGACATCCGGGCCAGCCAAGTGGCACGTTGGACTGTGGATGAGGTGGCTGAGTTTGTACAGTCTCTT CTGGGCTGTGAAGAGCATGCCAAGTGCTTTAAGAAAGAGCAGATCGATGGCAAAGCCTTCCTGCTTCTGACACAGACGGACATTGTCAAA GTGATGAAGATCAAACTGGGCCCAGCACTGAAGATTTACAACTCTATCCTGATGTTCAGGCATTCCCAGGAACTCCCTGAAGAAGATATT >In-frame_POLR3K_ENST00000293860_chr16_101558_-_L3MBTL4_ENST00000400104_chr18_6215834_-_1020nt ATGCTGCTGTTCTGCCCCGGCTGCGGGAACGGGCTGATCGTGGAGGAGGGACAACGCTGCCACCGCTTCTCCTGCAACACGTGCCCCTAC GTGCACAACATCACCCGCAAGGTAACAAATCGGAAGTACCCAAAACTGAAAGAAGTGGATGATGTGCTTGGTGGAGCAGCTGCCTGGGAG AATGTTGACTCTACTGCAGGTTATCCCAATCCAGAAAATTTTTCCTGGACAGAATACCTGGAAGCTACTCAAACCAATGCAGTTCCTGCC AAAGTTTTTAAAATGAGGTTGCCTCATGGTTTTCTGCCAAATATGAAACTTGAAGTTGTGGATAAACGGAACCCCAGGTTAATTCGTGTT GCTACGATTGTAGATGTTGATGACCAAAGAGTAAAGGTTCATTTTGATGGTTGGGACCATAAGTATGACTACTGGGTGGAGGCAGACAGC CCTGATATCCACCCGATCGGATGGTGTGATGTCACAGGGCATCCACTGGAAGTGCCACAGCGAACGAATGACCTGAAGATCCTTCCAGGT CAAGCTGTCTGTCCTACTCCCGGGTGCCGAGGAATAGGCCATATCCGTGGTCCACGTTATTCGGGACATCACAGTGCTTTTGGCTGCCCG TATTCAGACATGAACTTGAAAAAGGAGGCAACACTTCACGATCGTTTGAGAGAACAAACACAGGCAAATTTGGAATCAGACTCTTCACAT TCAAAATCAAAAAGCCTCTGTAGTTTGAACTTCAATGGAAAACATGAAAAGGTGAACAGTCAGCCCAGACTTGTACAGCAGGCAAAGTGT TTGAAAATCAAAGGAAAAGAAGATATTGACTTGGATAATCTCTTCAGAGGCCGAGTGCGGTGGCTCATGCCTGTAATCCCAGCACTTTGG GAGGCCGAGGCAGGCAGATCACGAGATCAGGAGATCAAGACCATCCTGGCCAACGCAGTGAAACCCCGTCTCTACCAAAAATACAAAAAA >In-frame_POLR3K_ENST00000293860_chr16_101558_-_L3MBTL4_ENST00000535782_chr18_6215834_-_1260nt ATGCTGCTGTTCTGCCCCGGCTGCGGGAACGGGCTGATCGTGGAGGAGGGACAACGCTGCCACCGCTTCTCCTGCAACACGTGCCCCTAC GTGCACAACATCACCCGCAAGGTAACAAATCGGAAGTACCCAAAACTGAAAGAAGTGGATGATGTGCTTGGTGGAGCAGCTGCCTGGGAG AATGTTGACTCTACTGCAGGTTATCCCAATCCAGAAAATTTTTCCTGGACAGAATACCTGGAAGCTACTCAAACCAATGCAGTTCCTGCC AAAGTTTTTAAAATGAGGTTGCCTCATGGTTTTCTGCCAAATATGAAACTTGAAGTTGTGGATAAACGGAACCCCAGGTTAATTCGTGTT GCTACGATTGTAGATGTTGATGACCAAAGAGTAAAGGTTCATTTTGATGGTTGGGACCATAAGTATGACTACTGGGTGGAGGCAGACAGC CCTGATATCCACCCGATCGGATGGTGTGATGTCACAGGGCATCCACTGGAAGTGCCACAGCGAACGAATGACCTGAAGATCCTTCCAGGT CAAGCTGTCTGTCCTACTCCCGGGTGCCGAGGAATAGGCCATATCCGTGGTCCACGTTATTCGGGACATCACAGTGCTTTTGGCTGCCCG TATTCAGACATGAACTTGAAAAAGGAGGCAACACTTCACGATCGTTTGAGAGAACAAACACAGGCAAATTTGGAATCAGACTCTTCACAT TCAAAATCAAAAAGCCTCTGTAGTTTGAACTTCAATGGAAAACATGAAAAGGTGAACAGTCAGCCCAGACTTGTACAGCAGGCAAAGTGT TTGAAAATCAAAGGAAAAGAAGATATTGACTTGGATAATCTCTTCAGAGAATACTCGGTGGAGCAGGCGCAGCAGGTGCTTCACCAGTCA GTGTCCATGTCCACGGTGTCAGCCCACCCTTTTCGGGACCTTCCCCTCGGCAGGGAGCAACACTGCAAGTTGCTTCCAGGCGTGGCTGAC ATCCGGGCCAGCCAAGTGGCACGTTGGACTGTGGATGAGGTGGCTGAGTTTGTACAGTCTCTTCTGGGCTGTGAAGAGCATGCCAAGTGC TTTAAGAAAGAGCAGATCGATGGCAAAGCCTTCCTGCTTCTGACACAGACGGACATTGTCAAAGTGATGAAGATCAAACTGGGCCCAGCA CTGAAGATTTACAACTCTATCCTGATGTTCAGGCATTCCCAGGAACTCCCTGAAGAAGATATTGCCTCAGGCCAAGAAGTCAGGGGATGA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_POLR3K_ENST00000293860_chr16_101558_-_L3MBTL4_ENST00000400105_chr18_6215834_-_2843nt AGTGGGAGCTGCCGGGAGTTGGAGCCTGCGGAGTTCGAGACCATGCTGCTGTTCTGCCCCGGCTGCGGGAACGGGCTGATCGTGGAGGAG GGACAACGCTGCCACCGCTTCTCCTGCAACACGTGCCCCTACGTGCACAACATCACCCGCAAGGTAACAAATCGGAAGTACCCAAAACTG AAAGAAGTGGATGATGTGCTTGGTGGAGCAGCTGCCTGGGAGAATGTTGACTCTACTGCAGGTTATCCCAATCCAGAAAATTTTTCCTGG ACAGAATACCTGGAAGCTACTCAAACCAATGCAGTTCCTGCCAAAGTTTTTAAAATGAGGTTGCCTCATGGTTTTCTGCCAAATATGAAA CTTGAAGTTGTGGATAAACGGAACCCCAGGTTAATTCGTGTTGCTACGATTGTAGATGTTGATGACCAAAGAGTAAAGGTTCATTTTGAT GGTTGGGACCATAAGTATGACTACTGGGTGGAGGCAGACAGCCCTGATATCCACCCGATCGGATGGTGTGATGTCACAGGGCATCCACTG GAAGTGCCACAGCGAACGAATGACCTGAAGATCCTTCCAGGTCAAGCTGTCTGTCCTACTCCCGGGTGCCGAGGAATAGGCCATATCCGT GGTCCACGTTATTCGGGACATCACAGTGCTTTTGGCTGCCCGTATTCAGACATGAACTTGAAAAAGGAGGCAACACTTCACGATCGTTTG AGAGAACAAACACAGGCAAATTTGGAATCAGACTCTTCACATTCAAAATCAAAAAGCCTCTGTAGTTTGAACTTCAATGGAAAACATGAA AAGGTGAACAGTCAGCCCAGACTTGTACAGCAGGCAAAGTGTTTGAAAATCAAAGGAAAAGAAGATATTGACTTGGATAATCTCTTCAGA GTGCTTGTGCTGCATCCCAGAGGTTTGGAATACTCGGTGGAGCAGGCGCAGCAGGTGCTTCACCAGTCAGTGTCCATGTCCACGGTGTCA GCCCACCCTTTTCGGGACCTTCCCCTCGGCAGGGAGCAACACTGCAAGTTGCTTCCAGGCGTGGCTGACATCCGGGCCAGCCAAGTGGCA CGTTGGACTGTGGATGAGGTGGCTGAGTTTGTACAGTCTCTTCTGGGCTGTGAAGAGCATGCCAAGTGCTTTAAGAAAGAGCAGATCGAT GGCAAAGCCTTCCTGCTTCTGACACAGACGGACATTGTCAAAGTGATGAAGATCAAACTGGGCCCAGCACTGAAGATTTACAACTCTATC CTGATGTTCAGGCATTCCCAGGAACTCCCTGAAGAAGATATTGCCTCAGGCCAAGAAGTCAGGGGATGAATGGGCTCCCTGAACTTCCTC TGGCACCAAGACCTGCGCTCTTTCAGCAATAAAAGTGGAGCACATTAATTTGATGTGAATGTCCCCATGGCCGTATCCACACTGAATCTG GACTTTTTAAAGTGTCTGTGATTTGTTTACATGTTTAGAGGATTTTGATGACTGGTCCAGTGCCAATGACTCAGAGGCTTAGGCCCATCT GTGGGTTTGGTTTACGAACATTGTTATCTTTGGTGGGATCCGCTCAGCTCTGATTTGTTTGCAAGACAGACCAAAGAAGCCCACACATCC ACCTTTATTCTTCTCCGTCACCAGAAAAGAAACCATTTTCCATCTTACAAGCATAACACTCTCAAGTGGTGAAATATTAGAAAAGCAGTG TTCATGAATACATCGTTAATGTTTTTACCAGAGCAACATCGAGCTTGGCTCAGATCTGCCATGGAGCACAGCTAGTCTAAGAGCTAGAGG CCTGGTGCTTTCAAAAGACTTCATGTGAGATTTTTGTGTACTTTACTCAGGAAAGTGTGAATCTCTAAAAAATAATAATAATAAGCACAT GTTTTCATGATTCATTAATTCTCCTTTTTGTTCCATTAACCATTTCTTGGTTGTGCTCCCAAGCTTTCCTGGAGCCTCCACAAAGGAGAG TAGCCAGGAGTAATGAGAGGACGGTCAGGTGGGCACTTCCAAAAGCTGGAGAGACCCTTCTGAGGACCCTCCACCATCAGCGGGGCCTCA GGGGACCCTGTCCTAACACTGGTGTGGCTGCTGGGCCAGACGCTCACCTGCACAGAACTCCTCCCTGCTCCCACTCTGAAGGGCGTTTCA GAATTGACTCATTTCCACTGCAGTCTGCCAGAACCCCTGTAATAAGGAGCTGTGTTATATTACATCTGGGGCTGTGTGCATCTTTACAAA TGGAGACACACTATTCAAAGGGAAGATCTCTAAAGTAGGGAGCGTGGTACTTATTCTTTGTTTGAAACATTCCGATTTGTTGTCAGGCCT TATTTGTTTTTTGTAAGTGATTGTATCGGAGGCTTAAGTTGTGTGGAATCAGTCCCACAGTGTTGAAAGACAAGTACCTCTTTTCTGACA CTTCTTACTACTTTTACAGGTAGTAACAGCTACAAATACTCTCCCAGAAGTGGAGGGACACCATTTGTGGGTGGGGAGAAAGAGGGAGAG GTTCTATGTCCACTTGCTTCATTAAGAATGTTAAGGTTTAAGAAAGTTGATTCTGCTTGGAGAATTTCTCAAGCTTTACATTTTTTTTTC ACTGAAGAAAATAAACAAACTCTAAGAGGTGTGCATATATAACATTTCTTTAGATCTTTACCTAAAAGGAATTTTAATATATTATTGGTT GATGTAAATTTTGTTTCTGTGGAGTTTTGTTTGTTTTGCTTTTTGTAGACTGCCATGTGCAAGTAAAATTCCTGCTTCTGCCATGTTAAA >In-frame_POLR3K_ENST00000293860_chr16_101558_-_L3MBTL4_ENST00000317931_chr18_6215834_-_2816nt AGTGGGAGCTGCCGGGAGTTGGAGCCTGCGGAGTTCGAGACCATGCTGCTGTTCTGCCCCGGCTGCGGGAACGGGCTGATCGTGGAGGAG GGACAACGCTGCCACCGCTTCTCCTGCAACACGTGCCCCTACGTGCACAACATCACCCGCAAGGTAACAAATCGGAAGTACCCAAAACTG AAAGAAGTGGATGATGTGCTTGGTGGAGCAGCTGCCTGGGAGAATGTTGACTCTACTGCAGGTTATCCCAATCCAGAAAATTTTTCCTGG ACAGAATACCTGGAAGCTACTCAAACCAATGCAGTTCCTGCCAAAGTTTTTAAAATGAGGTTGCCTCATGGTTTTCTGCCAAATATGAAA CTTGAAGTTGTGGATAAACGGAACCCCAGGTTAATTCGTGTTGCTACGATTGTAGATGTTGATGACCAAAGAGTAAAGGTTCATTTTGAT GGTTGGGACCATAAGTATGACTACTGGGTGGAGGCAGACAGCCCTGATATCCACCCGATCGGATGGTGTGATGTCACAGGGCATCCACTG GAAGTGCCACAGCGAACGAATGACCTGAAGATCCTTCCAGGTCAAGCTGTCTGTCCTACTCCCGGGTGCCGAGGAATAGGCCATATCCGT GGTCCACGTTATTCGGGACATCACAGTGCTTTTGGCTGCCCGTATTCAGACATGAACTTGAAAAAGGAGGCAACACTTCACGATCGTTTG AGAGAACAAACACAGGCAAATTTGGAATCAGACTCTTCACATTCAAAATCAAAAAGCCTCTGTAGTTTGAACTTCAATGGAAAACATGAA AAGGTGAACAGTCAGCCCAGACTTGTACAGCAGGCAAAGTGTTTGAAAATCAAAGGAAAAGAAGATATTGACTTGGATAATCTCTTCAGA GAATACTCGGTGGAGCAGGCGCAGCAGGTGCTTCACCAGTCAGTGTCCATGTCCACGGTGTCAGCCCACCCTTTTCGGGACCTTCCCCTC GGCAGGGAGCAACACTGCAAGTTGCTTCCAGGCGTGGCTGACATCCGGGCCAGCCAAGTGGCACGTTGGACTGTGGATGAGGTGGCTGAG TTTGTACAGTCTCTTCTGGGCTGTGAAGAGCATGCCAAGTGCTTTAAGAAAGAGCAGATCGATGGCAAAGCCTTCCTGCTTCTGACACAG ACGGACATTGTCAAAGTGATGAAGATCAAACTGGGCCCAGCACTGAAGATTTACAACTCTATCCTGATGTTCAGGCATTCCCAGGAACTC CCTGAAGAAGATATTGCCTCAGGCCAAGAAGTCAGGGGATGAATGGGCTCCCTGAACTTCCTCTGGCACCAAGACCTGCGCTCTTTCAGC AATAAAAGTGGAGCACATTAATTTGATGTGAATGTCCCCATGGCCGTATCCACACTGAATCTGGACTTTTTAAAGTGTCTGTGATTTGTT TACATGTTTAGAGGATTTTGATGACTGGTCCAGTGCCAATGACTCAGAGGCTTAGGCCCATCTGTGGGTTTGGTTTACGAACATTGTTAT CTTTGGTGGGATCCGCTCAGCTCTGATTTGTTTGCAAGACAGACCAAAGAAGCCCACACATCCACCTTTATTCTTCTCCGTCACCAGAAA AGAAACCATTTTCCATCTTACAAGCATAACACTCTCAAGTGGTGAAATATTAGAAAAGCAGTGTTCATGAATACATCGTTAATGTTTTTA CCAGAGCAACATCGAGCTTGGCTCAGATCTGCCATGGAGCACAGCTAGTCTAAGAGCTAGAGGCCTGGTGCTTTCAAAAGACTTCATGTG AGATTTTTGTGTACTTTACTCAGGAAAGTGTGAATCTCTAAAAAATAATAATAATAAGCACATGTTTTCATGATTCATTAATTCTCCTTT TTGTTCCATTAACCATTTCTTGGTTGTGCTCCCAAGCTTTCCTGGAGCCTCCACAAAGGAGAGTAGCCAGGAGTAATGAGAGGACGGTCA GGTGGGCACTTCCAAAAGCTGGAGAGACCCTTCTGAGGACCCTCCACCATCAGCGGGGCCTCAGGGGACCCTGTCCTAACACTGGTGTGG CTGCTGGGCCAGACGCTCACCTGCACAGAACTCCTCCCTGCTCCCACTCTGAAGGGCGTTTCAGAATTGACTCATTTCCACTGCAGTCTG CCAGAACCCCTGTAATAAGGAGCTGTGTTATATTACATCTGGGGCTGTGTGCATCTTTACAAATGGAGACACACTATTCAAAGGGAAGAT CTCTAAAGTAGGGAGCGTGGTACTTATTCTTTGTTTGAAACATTCCGATTTGTTGTCAGGCCTTATTTGTTTTTTGTAAGTGATTGTATC GGAGGCTTAAGTTGTGTGGAATCAGTCCCACAGTGTTGAAAGACAAGTACCTCTTTTCTGACACTTCTTACTACTTTTACAGGTAGTAAC AGCTACAAATACTCTCCCAGAAGTGGAGGGACACCATTTGTGGGTGGGGAGAAAGAGGGAGAGGTTCTATGTCCACTTGCTTCATTAAGA ATGTTAAGGTTTAAGAAAGTTGATTCTGCTTGGAGAATTTCTCAAGCTTTACATTTTTTTTTCACTGAAGAAAATAAACAAACTCTAAGA GGTGTGCATATATAACATTTCTTTAGATCTTTACCTAAAAGGAATTTTAATATATTATTGGTTGATGTAAATTTTGTTTCTGTGGAGTTT TGTTTGTTTTGCTTTTTGTAGACTGCCATGTGCAAGTAAAATTCCTGCTTCTGCCATGTTAAAATTTTAATATATTTTAAATGATAATAA >In-frame_POLR3K_ENST00000293860_chr16_101558_-_L3MBTL4_ENST00000284898_chr18_6215834_-_2842nt AGTGGGAGCTGCCGGGAGTTGGAGCCTGCGGAGTTCGAGACCATGCTGCTGTTCTGCCCCGGCTGCGGGAACGGGCTGATCGTGGAGGAG GGACAACGCTGCCACCGCTTCTCCTGCAACACGTGCCCCTACGTGCACAACATCACCCGCAAGGTAACAAATCGGAAGTACCCAAAACTG AAAGAAGTGGATGATGTGCTTGGTGGAGCAGCTGCCTGGGAGAATGTTGACTCTACTGCAGGTTATCCCAATCCAGAAAATTTTTCCTGG ACAGAATACCTGGAAGCTACTCAAACCAATGCAGTTCCTGCCAAAGTTTTTAAAATGAGGTTGCCTCATGGTTTTCTGCCAAATATGAAA CTTGAAGTTGTGGATAAACGGAACCCCAGGTTAATTCGTGTTGCTACGATTGTAGATGTTGATGACCAAAGAGTAAAGGTTCATTTTGAT GGTTGGGACCATAAGTATGACTACTGGGTGGAGGCAGACAGCCCTGATATCCACCCGATCGGATGGTGTGATGTCACAGGGCATCCACTG GAAGTGCCACAGCGAACGAATGACCTGAAGATCCTTCCAGGTCAAGCTGTCTGTCCTACTCCCGGGTGCCGAGGAATAGGCCATATCCGT GGTCCACGTTATTCGGGACATCACAGTGCTTTTGGCTGCCCGTATTCAGACATGAACTTGAAAAAGGAGGCAACACTTCACGATCGTTTG AGAGAACAAACACAGGCAAATTTGGAATCAGACTCTTCACATTCAAAATCAAAAAGCCTCTGTAGTTTGAACTTCAATGGAAAACATGAA AAGGTGAACAGTCAGCCCAGACTTGTACAGCAGGCAAAGTGTTTGAAAATCAAAGGAAAAGAAGATATTGACTTGGATAATCTCTTCAGA GTGCTTGTGCTGCATCCCAGAGGTTTGGAATACTCGGTGGAGCAGGCGCAGCAGGTGCTTCACCAGTCAGTGTCCATGTCCACGGTGTCA GCCCACCCTTTTCGGGACCTTCCCCTCGGCAGGGAGCAACACTGCAAGTTGCTTCCAGGCGTGGCTGACATCCGGGCCAGCCAAGTGGCA CGTTGGACTGTGGATGAGGTGGCTGAGTTTGTACAGTCTCTTCTGGGCTGTGAAGAGCATGCCAAGTGCTTTAAGAAAGAGCAGATCGAT GGCAAAGCCTTCCTGCTTCTGACACAGACGGACATTGTCAAAGTGATGAAGATCAAACTGGGCCCAGCACTGAAGATTTACAACTCTATC CTGATGTTCAGGCATTCCCAGGAACTCCCTGAAGAAGATATTGCCTCAGGCCAAGAAGTCAGGGGATGAATGGGCTCCCTGAACTTCCTC TGGCACCAAGACCTGCGCTCTTTCAGCAATAAAAGTGGAGCACATTAATTTGATGTGAATGTCCCCATGGCCGTATCCACACTGAATCTG GACTTTTTAAAGTGTCTGTGATTTGTTTACATGTTTAGAGGATTTTGATGACTGGTCCAGTGCCAATGACTCAGAGGCTTAGGCCCATCT GTGGGTTTGGTTTACGAACATTGTTATCTTTGGTGGGATCCGCTCAGCTCTGATTTGTTTGCAAGACAGACCAAAGAAGCCCACACATCC ACCTTTATTCTTCTCCGTCACCAGAAAAGAAACCATTTTCCATCTTACAAGCATAACACTCTCAAGTGGTGAAATATTAGAAAAGCAGTG TTCATGAATACATCGTTAATGTTTTTACCAGAGCAACATCGAGCTTGGCTCAGATCTGCCATGGAGCACAGCTAGTCTAAGAGCTAGAGG CCTGGTGCTTTCAAAAGACTTCATGTGAGATTTTTGTGTACTTTACTCAGGAAAGTGTGAATCTCTAAAAAATAATAATAATAAGCACAT GTTTTCATGATTCATTAATTCTCCTTTTTGTTCCATTAACCATTTCTTGGTTGTGCTCCCAAGCTTTCCTGGAGCCTCCACAAAGGAGAG TAGCCAGGAGTAATGAGAGGACGGTCAGGTGGGCACTTCCAAAAGCTGGAGAGACCCTTCTGAGGACCCTCCACCATCAGCGGGGCCTCA GGGGACCCTGTCCTAACACTGGTGTGGCTGCTGGGCCAGACGCTCACCTGCACAGAACTCCTCCCTGCTCCCACTCTGAAGGGCGTTTCA GAATTGACTCATTTCCACTGCAGTCTGCCAGAACCCCTGTAATAAGGAGCTGTGTTATATTACATCTGGGGCTGTGTGCATCTTTACAAA TGGAGACACACTATTCAAAGGGAAGATCTCTAAAGTAGGGAGCGTGGTACTTATTCTTTGTTTGAAACATTCCGATTTGTTGTCAGGCCT TATTTGTTTTTTGTAAGTGATTGTATCGGAGGCTTAAGTTGTGTGGAATCAGTCCCACAGTGTTGAAAGACAAGTACCTCTTTTCTGACA CTTCTTACTACTTTTACAGGTAGTAACAGCTACAAATACTCTCCCAGAAGTGGAGGGACACCATTTGTGGGTGGGGAGAAAGAGGGAGAG GTTCTATGTCCACTTGCTTCATTAAGAATGTTAAGGTTTAAGAAAGTTGATTCTGCTTGGAGAATTTCTCAAGCTTTACATTTTTTTTTC ACTGAAGAAAATAAACAAACTCTAAGAGGTGTGCATATATAACATTTCTTTAGATCTTTACCTAAAAGGAATTTTAATATATTATTGGTT GATGTAAATTTTGTTTCTGTGGAGTTTTGTTTGTTTTGCTTTTTGTAGACTGCCATGTGCAAGTAAAATTCCTGCTTCTGCCATGTTAAA >In-frame_POLR3K_ENST00000293860_chr16_101558_-_L3MBTL4_ENST00000400104_chr18_6215834_-_3790nt AGTGGGAGCTGCCGGGAGTTGGAGCCTGCGGAGTTCGAGACCATGCTGCTGTTCTGCCCCGGCTGCGGGAACGGGCTGATCGTGGAGGAG GGACAACGCTGCCACCGCTTCTCCTGCAACACGTGCCCCTACGTGCACAACATCACCCGCAAGGTAACAAATCGGAAGTACCCAAAACTG AAAGAAGTGGATGATGTGCTTGGTGGAGCAGCTGCCTGGGAGAATGTTGACTCTACTGCAGGTTATCCCAATCCAGAAAATTTTTCCTGG ACAGAATACCTGGAAGCTACTCAAACCAATGCAGTTCCTGCCAAAGTTTTTAAAATGAGGTTGCCTCATGGTTTTCTGCCAAATATGAAA CTTGAAGTTGTGGATAAACGGAACCCCAGGTTAATTCGTGTTGCTACGATTGTAGATGTTGATGACCAAAGAGTAAAGGTTCATTTTGAT GGTTGGGACCATAAGTATGACTACTGGGTGGAGGCAGACAGCCCTGATATCCACCCGATCGGATGGTGTGATGTCACAGGGCATCCACTG GAAGTGCCACAGCGAACGAATGACCTGAAGATCCTTCCAGGTCAAGCTGTCTGTCCTACTCCCGGGTGCCGAGGAATAGGCCATATCCGT GGTCCACGTTATTCGGGACATCACAGTGCTTTTGGCTGCCCGTATTCAGACATGAACTTGAAAAAGGAGGCAACACTTCACGATCGTTTG AGAGAACAAACACAGGCAAATTTGGAATCAGACTCTTCACATTCAAAATCAAAAAGCCTCTGTAGTTTGAACTTCAATGGAAAACATGAA AAGGTGAACAGTCAGCCCAGACTTGTACAGCAGGCAAAGTGTTTGAAAATCAAAGGAAAAGAAGATATTGACTTGGATAATCTCTTCAGA GGCCGAGTGCGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGCAGATCACGAGATCAGGAGATCAAGACCATCCTG GCCAACGCAGTGAAACCCCGTCTCTACCAAAAATACAAAAAATTAGCCAGGCGTGGTGGCGGGTGCCTATAGTCCCACCTACTGGGGAAG CTGAGGCAGGAGAATTGCTTGAACCTGGGAGGCAGAGATTACACTGACCTGAGATTGCACCACTGCACTCCAGCCTGGGCAACAGAGCAA GACTCCGTCTCAAAAAAAAAAAGAAAGAAAGAAAAAATGGTGGAAAGGGTGGAGAAATTCCTTTTAATGGGTACAAACCACACAATGCAG GTGACCATTACTCTAAAAGCCCAGGCTTCATCACTATGCAATATATCTGTGTAACAAAACTGTACTTGTGCCTGCTAAATCTGTGAAATT AAAAAAAAAAAAAAACCATGAATCTGATTTGCCTTTAGTCACCAGATGACTGCAGATAGGCACACAGAGGTGTGAGACAGCACTTTCCAT TTGCCCTTCATCTCTTGTTCCTCTGCCATTCCCCATGAAGCCGTGCTGGGGCTGACCTGCTGGAGGATGAGACCTGTGAAGCTGAGTCAG CTGCCCTGGTCATCCCAGCCAAGGCCATGTCCTCTCTGCTCAGCCAACAACTGTCCAACAAACATGTGAATGAGCCCTGCTGAAATCAGA ACTGACCGGCCCACCTGAGCCTAAATTCCTGACAAACAGATGTGTGAACTAAGTAAATACTTAAAAAAATGAGATGCTGATGGTCCCTGA ATTTCTCAAGAGGCAAAGAATGGTCCCACCTCGCAACTTATAAATGTTCAGAAGTTAGACGGCCACAAAGAAGTAGCACCTCATATACAT TCTCTTGCTATCTACAATAAGGTGAAGGAAGGCATTTATCTTCTCTGCAACCAGAAAACCTATAACCCAAATGCCCAGGAACACAAGAAC ACTGTTCACCATTCTGCTGTGCTTATTAGCAGAAGATATATCAGCTCACAAAATCCCCTTTGAAACAGAAACTAAAATAATGCTCAATGA TCATTCTACTCCCACGGGGGAGGAGGGAGAGGAGCATAAATCAGGACAAGAGCTGGGTTTAGAACTTGGATCACGTGTGGCTTTTCTCCA TGATCACAAACCCCAGCTTCCTATAATTAATAATTGGATGTATTAAGTGTTTTATGGAGCAGTCCAGCCAGAGAGCAACTATAAAATGGA AACATGGACCAGCTTGGTAAAGGGAAAGATGAAATTGTAGAATTAATTTGTTTGTTCGTTCATTGAGTATTTCATAACAATAAACTTATT GTATTTATAAAGGGAAAAACCTCTGGGTGTAATTTGGCTGCCTGGTTGTTTATATCCTACAGTGCAGTTTCAGTATGTTTCATGTTAGTG TGCCTGTTTTAAAATGTTTTACTTCATTATCGTAAGACGTTTTTAATGCAATGAAACTTCAAGCCAGAAAAATCTTAGAAAATTAACGAA ATAGGGAGTAGAGAGAAATGGAGATAGCATTAAACTAAATACAAAGAAAAAATTGAAACAAATTTTTTTATTTGACAAAAATTAGCCGGG TGTGGTGGCAGGCACCTGTAATCCCAGCTACTCAGGAAGCTGAGGCGAGAGAATCGCTTGAACCTGGGAGGTGGAGGCAGTGAGCTGAGA TCGTGCCACTGTACATCACCAGCCTGGGCGACAGAGTGAGACTCCTTCTCCAAAAAAAAAAAAAAGAGTCTCTTCATTAAAATAAACCTA ATACTTCACTTGTTTAGTAAAGCAATGCAAATTAATACCTGATGATAAAGTCAGAAGATGTATATATGTTTGTGTTCCTGCTTTCTTTCA TTTCACAGTCTAATTCTCCCAGACTAGGATTTTTGCTAGCTATTTGTTCTATCACCCAGAATTTTGAGAAGGCTTAAAAGCATATTATTG ATTTGTGCATTTGGTGCAAAATTCAACAGGTATAAGGGGGTATCTCTCCCTGAACCTGATCCTCAGCCTTCAGTTTCCTCCCTTGGAATA ATCACTGTATACTTCTCTTGTGTGTCTTTCTAAAAATATGTTCTGTTTATTTAAATATATGTGTGTATGTGTATTTACACAAGTGATGGC ATACCACATACATTGTTAAACAGTTTCCTCGTGTCCTTTAGCAATAAAATCTGACGAGCAGTTCTTAACACATGGAGCGGCACACTATAA GTGACCAGTCCCTGCCCATGGCCATCTGGATGGTTTTCATGTTGCTGTGTAAAGGAGGCTTCAAAGTGTCTTCTGTAGGTGTCAGCTTGA CTGGAAAATAAAAAGTGTCTTCTGTACTCATCACTCATGCTTGTGAGAATCTACAGGATAGATTCTGTGTGTGAATCTATCCTATTCTAA TCCTTTTCGGCATTTCCTCAGCTACCCTTACTCGTTCATTTTTCCAAATGAACTTTAATATCAGTTTTTCTGGTACAACTTTTTTCCATT CCAGTTGGTTAATTTTTGGATTGCAATAAATTTATGATTTAACTTTTAATTTTACCCTTTGTGAACTTGACCATAGTAAGCTGTTCCCAT ACTCAAATATTTCCTGTCCTGTAATTGCATTTTAAGTTTTCCTTTATGTAGAACTTGCGTCCTTCTTACGAAGTTTATTCCTAAGCAGTT TATCGTTTTTGTTGCTGCAATAAATGGACGTATTTCTTCCTTGATGTCCTCCACCTAAGATTGTCTGTATGGAAAGATTGTATATTTCTG TGTATTACATTTAATCCTGCCACTGTAATCTCTTCTAATTTGTAATTTTTTTCATGTAATTATTTTGGGTTTCTAGGTAAATAAACATGT >In-frame_POLR3K_ENST00000293860_chr16_101558_-_L3MBTL4_ENST00000535782_chr18_6215834_-_2808nt AGTGGGAGCTGCCGGGAGTTGGAGCCTGCGGAGTTCGAGACCATGCTGCTGTTCTGCCCCGGCTGCGGGAACGGGCTGATCGTGGAGGAG GGACAACGCTGCCACCGCTTCTCCTGCAACACGTGCCCCTACGTGCACAACATCACCCGCAAGGTAACAAATCGGAAGTACCCAAAACTG AAAGAAGTGGATGATGTGCTTGGTGGAGCAGCTGCCTGGGAGAATGTTGACTCTACTGCAGGTTATCCCAATCCAGAAAATTTTTCCTGG ACAGAATACCTGGAAGCTACTCAAACCAATGCAGTTCCTGCCAAAGTTTTTAAAATGAGGTTGCCTCATGGTTTTCTGCCAAATATGAAA CTTGAAGTTGTGGATAAACGGAACCCCAGGTTAATTCGTGTTGCTACGATTGTAGATGTTGATGACCAAAGAGTAAAGGTTCATTTTGAT GGTTGGGACCATAAGTATGACTACTGGGTGGAGGCAGACAGCCCTGATATCCACCCGATCGGATGGTGTGATGTCACAGGGCATCCACTG GAAGTGCCACAGCGAACGAATGACCTGAAGATCCTTCCAGGTCAAGCTGTCTGTCCTACTCCCGGGTGCCGAGGAATAGGCCATATCCGT GGTCCACGTTATTCGGGACATCACAGTGCTTTTGGCTGCCCGTATTCAGACATGAACTTGAAAAAGGAGGCAACACTTCACGATCGTTTG AGAGAACAAACACAGGCAAATTTGGAATCAGACTCTTCACATTCAAAATCAAAAAGCCTCTGTAGTTTGAACTTCAATGGAAAACATGAA AAGGTGAACAGTCAGCCCAGACTTGTACAGCAGGCAAAGTGTTTGAAAATCAAAGGAAAAGAAGATATTGACTTGGATAATCTCTTCAGA GAATACTCGGTGGAGCAGGCGCAGCAGGTGCTTCACCAGTCAGTGTCCATGTCCACGGTGTCAGCCCACCCTTTTCGGGACCTTCCCCTC GGCAGGGAGCAACACTGCAAGTTGCTTCCAGGCGTGGCTGACATCCGGGCCAGCCAAGTGGCACGTTGGACTGTGGATGAGGTGGCTGAG TTTGTACAGTCTCTTCTGGGCTGTGAAGAGCATGCCAAGTGCTTTAAGAAAGAGCAGATCGATGGCAAAGCCTTCCTGCTTCTGACACAG ACGGACATTGTCAAAGTGATGAAGATCAAACTGGGCCCAGCACTGAAGATTTACAACTCTATCCTGATGTTCAGGCATTCCCAGGAACTC CCTGAAGAAGATATTGCCTCAGGCCAAGAAGTCAGGGGATGAATGGGCTCCCTGAACTTCCTCTGGCACCAAGACCTGCGCTCTTTCAGC AATAAAAGTGGAGCACATTAATTTGATGTGAATGTCCCCATGGCCGTATCCACACTGAATCTGGACTTTTTAAAGTGTCTGTGATTTGTT TACATGTTTAGAGGATTTTGATGACTGGTCCAGTGCCAATGACTCAGAGGCTTAGGCCCATCTGTGGGTTTGGTTTACGAACATTGTTAT CTTTGGTGGGATCCGCTCAGCTCTGATTTGTTTGCAAGACAGACCAAAGAAGCCCACACATCCACCTTTATTCTTCTCCGTCACCAGAAA AGAAACCATTTTCCATCTTACAAGCATAACACTCTCAAGTGGTGAAATATTAGAAAAGCAGTGTTCATGAATACATCGTTAATGTTTTTA CCAGAGCAACATCGAGCTTGGCTCAGATCTGCCATGGAGCACAGCTAGTCTAAGAGCTAGAGGCCTGGTGCTTTCAAAAGACTTCATGTG AGATTTTTGTGTACTTTACTCAGGAAAGTGTGAATCTCTAAAAAATAATAATAATAAGCACATGTTTTCATGATTCATTAATTCTCCTTT TTGTTCCATTAACCATTTCTTGGTTGTGCTCCCAAGCTTTCCTGGAGCCTCCACAAAGGAGAGTAGCCAGGAGTAATGAGAGGACGGTCA GGTGGGCACTTCCAAAAGCTGGAGAGACCCTTCTGAGGACCCTCCACCATCAGCGGGGCCTCAGGGGACCCTGTCCTAACACTGGTGTGG CTGCTGGGCCAGACGCTCACCTGCACAGAACTCCTCCCTGCTCCCACTCTGAAGGGCGTTTCAGAATTGACTCATTTCCACTGCAGTCTG CCAGAACCCCTGTAATAAGGAGCTGTGTTATATTACATCTGGGGCTGTGTGCATCTTTACAAATGGAGACACACTATTCAAAGGGAAGAT CTCTAAAGTAGGGAGCGTGGTACTTATTCTTTGTTTGAAACATTCCGATTTGTTGTCAGGCCTTATTTGTTTTTTGTAAGTGATTGTATC GGAGGCTTAAGTTGTGTGGAATCAGTCCCACAGTGTTGAAAGACAAGTACCTCTTTTCTGACACTTCTTACTACTTTTACAGGTAGTAAC AGCTACAAATACTCTCCCAGAAGTGGAGGGACACCATTTGTGGGTGGGGAGAAAGAGGGAGAGGTTCTATGTCCACTTGCTTCATTAAGA ATGTTAAGGTTTAAGAAAGTTGATTCTGCTTGGAGAATTTCTCAAGCTTTACATTTTTTTTTCACTGAAGAAAATAAACAAACTCTAAGA GGTGTGCATATATAACATTTCTTTAGATCTTTACCTAAAAGGAATTTTAATATATTATTGGTTGATGTAAATTTTGTTTCTGTGGAGTTT TGTTTGTTTTGCTTTTTGTAGACTGCCATGTGCAAGTAAAATTCCTGCTTCTGCCATGTTAAAATTTTAATATATTTTAAATGATAATAA 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FusionGenePPI for POLR3K_L3MBTL4 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| POLR3K | POLR3D, RFPL4B, GPN3, PIH1D1, POLR1C, CRCP, POLR2E, POLR2F, POLR3A, POLR3B, POLR3C, POLR3F, MUS81, PTTG1, POLR3E, POLR3GL | L3MBTL4 | APP, NINL |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for POLR3K_L3MBTL4 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for POLR3K_L3MBTL4 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | POLR3K | C0038356 | Stomach Neoplasms | 1 | CTD_human |
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