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Fusion gene ID: 27815 |
FusionGeneSummary for PMVK_FNBP1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PMVK_FNBP1 | Fusion gene ID: 27815 | Hgene | Tgene | Gene symbol | PMVK | FNBP1 | Gene ID | 10654 | 23048 |
| Gene name | phosphomevalonate kinase | formin binding protein 1 | |
| Synonyms | HUMPMKI|PMK|PMKA|PMKASE|POROK1 | FBP17 | |
| Cytomap | 1q21.3 | 9q34.11 | |
| Type of gene | protein-coding | protein-coding | |
| Description | phosphomevalonate kinasetestis tissue sperm-binding protein Li 95mP | formin-binding protein 1formin-binding protein 17 | |
| Modification date | 20180523 | 20180529 | |
| UniProtAcc | Q15126 | Q96RU3 | |
| Ensembl transtripts involved in fusion gene | ENST00000368467, | ENST00000446176, ENST00000420781, ENST00000355681, ENST00000443566, ENST00000478129, | |
| Fusion gene scores | * DoF score | 5 X 4 X 4=80 | 8 X 10 X 3=240 |
| # samples | 5 | 14 | |
| ** MAII score | log2(5/80*10)=-0.678071905112638 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(14/240*10)=-0.777607578663552 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: PMVK [Title/Abstract] AND FNBP1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | PMVK | GO:0006695 | cholesterol biosynthetic process | 8663599 |
| Hgene | PMVK | GO:0016126 | sterol biosynthetic process | 16519518 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | LIHC | TCGA-CC-5263-01A | PMVK | chr1 | 154909067 | - | FNBP1 | chr9 | 132691974 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000368467 | ENST00000446176 | PMVK | chr1 | 154909067 | - | FNBP1 | chr9 | 132691974 | - |
| In-frame | ENST00000368467 | ENST00000420781 | PMVK | chr1 | 154909067 | - | FNBP1 | chr9 | 132691974 | - |
| In-frame | ENST00000368467 | ENST00000355681 | PMVK | chr1 | 154909067 | - | FNBP1 | chr9 | 132691974 | - |
| 5CDS-intron | ENST00000368467 | ENST00000443566 | PMVK | chr1 | 154909067 | - | FNBP1 | chr9 | 132691974 | - |
| 5CDS-intron | ENST00000368467 | ENST00000478129 | PMVK | chr1 | 154909067 | - | FNBP1 | chr9 | 132691974 | - |
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FusionProtFeatures for PMVK_FNBP1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| PMVK | FNBP1 |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | PMVK | chr1:154909067 | chr9:132691974 | ENST00000368467 | - | 1 | 5 | 17_23 | 31 | 193 | Nucleotide binding | ATP |
| Tgene | >FNBP1 | chr1:154909067 | chr9:132691974 | ENST00000355681 | - | 5 | 16 | 398_490 | 171 | 593 | Coiled coil | Ontology_term=ECO:0000250 |
| Tgene | >FNBP1 | chr1:154909067 | chr9:132691974 | ENST00000446176 | - | 5 | 17 | 398_490 | 171 | 618 | Coiled coil | Ontology_term=ECO:0000250 |
| Tgene | >FNBP1 | chr1:154909067 | chr9:132691974 | ENST00000355681 | - | 5 | 16 | 340_345 | 171 | 593 | Compositional bias | Note=Poly-Pro |
| Tgene | >FNBP1 | chr1:154909067 | chr9:132691974 | ENST00000446176 | - | 5 | 17 | 340_345 | 171 | 618 | Compositional bias | Note=Poly-Pro |
| Tgene | >FNBP1 | chr1:154909067 | chr9:132691974 | ENST00000355681 | - | 5 | 16 | 404_481 | 171 | 593 | Domain | REM-1 |
| Tgene | >FNBP1 | chr1:154909067 | chr9:132691974 | ENST00000355681 | - | 5 | 16 | 550_611 | 171 | 593 | Domain | SH3 |
| Tgene | >FNBP1 | chr1:154909067 | chr9:132691974 | ENST00000446176 | - | 5 | 17 | 404_481 | 171 | 618 | Domain | REM-1 |
| Tgene | >FNBP1 | chr1:154909067 | chr9:132691974 | ENST00000446176 | - | 5 | 17 | 550_611 | 171 | 618 | Domain | SH3 |
| Tgene | >FNBP1 | chr1:154909067 | chr9:132691974 | ENST00000355681 | - | 5 | 16 | 251_617 | 171 | 593 | Region | Note=Required for self-association and induction of membrane tubulation |
| Tgene | >FNBP1 | chr1:154909067 | chr9:132691974 | ENST00000446176 | - | 5 | 17 | 251_617 | 171 | 618 | Region | Note=Required for self-association and induction of membrane tubulation |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | FNBP1 | chr1:154909067 | chr9:132691974 | ENST00000355681 | - | 5 | 16 | 67_259 | 171 | 593 | Coiled coil | Ontology_term=ECO:0000269 |
| Tgene | FNBP1 | chr1:154909067 | chr9:132691974 | ENST00000446176 | - | 5 | 17 | 67_259 | 171 | 618 | Coiled coil | Ontology_term=ECO:0000269 |
| Tgene | FNBP1 | chr1:154909067 | chr9:132691974 | ENST00000355681 | - | 5 | 16 | 1_264 | 171 | 593 | Domain | F-BAR |
| Tgene | FNBP1 | chr1:154909067 | chr9:132691974 | ENST00000446176 | - | 5 | 17 | 1_264 | 171 | 618 | Domain | F-BAR |
| Tgene | FNBP1 | chr1:154909067 | chr9:132691974 | ENST00000355681 | - | 5 | 16 | 1_79 | 171 | 593 | Region | Note=Required for self-association and induction of membrane tubulation |
| Tgene | FNBP1 | chr1:154909067 | chr9:132691974 | ENST00000446176 | - | 5 | 17 | 1_79 | 171 | 618 | Region | Note=Required for self-association and induction of membrane tubulation |
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FusionGeneSequence for PMVK_FNBP1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_PMVK_ENST00000368467_chr1_154909067_-_FNBP1_ENST00000446176_chr9_132691974_-_478aa MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRPDNKLKYVTKWQRTAKQITHPFSRNSTMSSMNITILTSPTSSRKYKRWRKGGL_EWES P_RHMQRLIGR_SQSLGSAWME__KQPNQLIRKMIHSW__KLINQGLSLLETLNLRITLSQ_SALCQITAFQIPEEKANQTSNLVANPKE STGRSSKKISLCPF_HPPISLPLPLLPLPHPLLFPTAPSLPSSKRNPSPIASTSS_PPNPKSTASGA_SVGFLSSWVQHRRISATSHLNK EGKSCSRKSMS_IKKFRRRWIKEMP_QK_KMST_RILRWETQPVWITN_QKSAKI_RNCE_RPRNLRPGWLRLKAGSQHAASRRAGRADC TTARTHPQSTTAPRTVRAQMAVTQRSRVRRVR_RCWPRILTTSLMMRSPSLP_GRAKLSTHLKVRMKERFP_LKEKHCMS_RKTKAMAGP >In-frame_PMVK_ENST00000368467_chr1_154909067_-_FNBP1_ENST00000420781_chr9_132691974_-_469aa MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRPDNKLKYVTKWQRTAKQITHPFSRNSTMSSMNITILTSPTSSRKYKRWRKGGL_EWES P_RHMQRLIGR_SQSLGSAWME__KQPNQLIRKMIHSW__KLINQGLSLLETLNLRITLSQ_SALCQITAFQIPEEKANQTSNLVANPKE STGRSSKKISLPLPLLPLPHPLLFPTAPSLPSSKRNPSPIASTSS_PPNPKSTASGA_SVGIASLCRVQHRRISATSHLNKEGKSCSRKS MS_IKKFRRRWIKEMP_QK_KMST_RILRWETQPVWITN_QKSAKI_RNCE_RPRNLRPGWLRLKAGSQHAASRRAGRADCTTARTHPQS TTAPRTVRAQMAVTQRSRVRRVR_RCWPRILTTSLMMRSPSLP_GRAKLSTHLKVRMKERFP_LKEKHCMS_RKTKAMAGPAFGEMKMKR >In-frame_PMVK_ENST00000368467_chr1_154909067_-_FNBP1_ENST00000355681_chr9_132691974_-_453aa MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRPDNKLKYVTKWQRTAKQITHPFSRNSTMSSMNITILTSPTSSRKYKRWRKGGL_EWES P_RHMQRLIGR_SQSLGSAWME__KQPNQLIRKMIHSW__KLINQGLSLLETLNLRITLSQ_SALCQITAFQIPEEKANQTSNLVANPKE STGRSSKKISLPSSKRNPSPIASTSS_PPNPKSTASGA_SVGFLSSWVQHRRISATSHLNKEGKSCSRKSMS_IKKFRRRWIKEMP_QK_ KMST_RILRWETQPVWITN_QKSAKI_RNCE_RPRNLRPGWLRLKAGSQHAASRRAGRADCTTARTHPQSTTAPRTVRAQMAVTQRSRVR RVR_RCWPRILTTSLMMRSPSLP_GRAKLSTHLKVRMKERFP_LKEKHCMS_RKTKAMAGPAFGEMKMKRVMSPLHMSKSVWTKMPKVLR |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_PMVK_ENST00000368467_chr1_154909067_-_FNBP1_ENST00000446176_chr9_132691974_-_1436nt ATGGCCCCGCTGGGAGGCGCCCCGCGGCTGGTACTGCTGTTCAGCGGCAAGAGGAAATCCGGGAAGGACTTCGTGACCGAGGCGCTGCAG AGCAGGCCCGACAACAAGCTCAAATACGTCACCAAATGGCAGAGGACAGCAAAGCAGATTACTCATCCATTCTCCAGAAATTCAACCATG AGCAGCATGAATATTACCATACTCACATCCCCAACATCTTCCAGAAAATACAAGAGATGGAGGAAAGGAGGATTGTGAGAATGGGAGAGT CCATGAAGACATATGCAGAGGTTGATCGGCAGGTGATCCCAATCATTGGGAAGTGCCTGGATGGAATAGTAAAAGCAGCCGAATCAATTG ATCAGAAAAATGATTCACAGCTGGTAATAGAAGCTTATAAATCAGGGTTTGAGCCTCCTGGAGACATTGAATTTGAGGATTACACTCAGC CAATGAAGCGCACTGTGTCAGATAACAGCCTTTCAAATTCCAGAGGAGAAGGCAAACCAGACCTCAAATTTGGTGGCAAATCCAAAGGAA AGTTATGGCCGTTCATCAAAAAAAATAAGCTTATGTCCCTTTTAACATCCCCCCATCAGCCTCCCCCTCCCCCTCCTGCCTCTGCCTCAC CCTCTGCTGTTCCCAACGGCCCCCAGTCTCCCAAGCAGCAAAAGGAACCCCTCTCCCATCGCTTCAACGAGTTCATGACCTCCAAACCCA AAATCCACTGCTTCAGGAGCCTAAAGCGTGGGCTTTCTCTCAAGCTGGGTGCAACACCGGAGGATTTCAGCAACCTCCCACCTGAACAAA GAAGGAAAAAGCTGCAGCAGAAAGTCGATGAGTTAAATAAAGAAATTCAGAAGGAGATGGATCAAAGAGATGCCATAACAAAAATGAAAG ATGTCTACCTAAAGAATCCTCAGATGGGAGACCCAGCCAGTTTGGATCACAAATTAGCAGAAGTCAGCCAAAATATAGAGAAACTGCGAG TAGAGACCCAGAAATTTGAGGCCTGGCTGGCTGAGGTTGAAGGCCGGCTCCCAGCACGCAGCGAGCAGGCGCGCCGGCAGAGCGGACTGT ACGACAGCCAGAACCCACCCACAGTCAACAACTGCGCCCAGGACCGTGAGAGCCCAGATGGCAGTTACACAGAGGAGCAGAGTCAGGAGA GTGAGATGAAGGTGCTGGCCACGGATTTTGACGACGAGTTTGATGATGAGGAGCCCCTCCCTGCCATAGGGACGTGCAAAGCTCTCTACA CATTTGAAGGTCAGAATGAAGGAACGATTTCCGTAGTTGAAGGAGAAACATTGTATGTCATAGAGGAAGACAAAGGCGATGGCTGGACCC >In-frame_PMVK_ENST00000368467_chr1_154909067_-_FNBP1_ENST00000420781_chr9_132691974_-_1409nt ATGGCCCCGCTGGGAGGCGCCCCGCGGCTGGTACTGCTGTTCAGCGGCAAGAGGAAATCCGGGAAGGACTTCGTGACCGAGGCGCTGCAG AGCAGGCCCGACAACAAGCTCAAATACGTCACCAAATGGCAGAGGACAGCAAAGCAGATTACTCATCCATTCTCCAGAAATTCAACCATG AGCAGCATGAATATTACCATACTCACATCCCCAACATCTTCCAGAAAATACAAGAGATGGAGGAAAGGAGGATTGTGAGAATGGGAGAGT CCATGAAGACATATGCAGAGGTTGATCGGCAGGTGATCCCAATCATTGGGAAGTGCCTGGATGGAATAGTAAAAGCAGCCGAATCAATTG ATCAGAAAAATGATTCACAGCTGGTAATAGAAGCTTATAAATCAGGGTTTGAGCCTCCTGGAGACATTGAATTTGAGGATTACACTCAGC CAATGAAGCGCACTGTGTCAGATAACAGCCTTTCAAATTCCAGAGGAGAAGGCAAACCAGACCTCAAATTTGGTGGCAAATCCAAAGGAA AGTTATGGCCGTTCATCAAAAAAAATAAGCCTCCCCCTCCCCCTCCTGCCTCTGCCTCACCCTCTGCTGTTCCCAACGGCCCCCAGTCTC CCAAGCAGCAAAAGGAACCCCTCTCCCATCGCTTCAACGAGTTCATGACCTCCAAACCCAAAATCCACTGCTTCAGGAGCCTAAAGCGTG GGCATAGCCTCACTCTGCAGGGTGCAACACCGGAGGATTTCAGCAACCTCCCACCTGAACAAAGAAGGAAAAAGCTGCAGCAGAAAGTCG ATGAGTTAAATAAAGAAATTCAGAAGGAGATGGATCAAAGAGATGCCATAACAAAAATGAAAGATGTCTACCTAAAGAATCCTCAGATGG GAGACCCAGCCAGTTTGGATCACAAATTAGCAGAAGTCAGCCAAAATATAGAGAAACTGCGAGTAGAGACCCAGAAATTTGAGGCCTGGC TGGCTGAGGTTGAAGGCCGGCTCCCAGCACGCAGCGAGCAGGCGCGCCGGCAGAGCGGACTGTACGACAGCCAGAACCCACCCACAGTCA ACAACTGCGCCCAGGACCGTGAGAGCCCAGATGGCAGTTACACAGAGGAGCAGAGTCAGGAGAGTGAGATGAAGGTGCTGGCCACGGATT TTGACGACGAGTTTGATGATGAGGAGCCCCTCCCTGCCATAGGGACGTGCAAAGCTCTCTACACATTTGAAGGTCAGAATGAAGGAACGA TTTCCGTAGTTGAAGGAGAAACATTGTATGTCATAGAGGAAGACAAAGGCGATGGCTGGACCCGCATTCGGAGAAATGAAGATGAAGAGG >In-frame_PMVK_ENST00000368467_chr1_154909067_-_FNBP1_ENST00000355681_chr9_132691974_-_1361nt ATGGCCCCGCTGGGAGGCGCCCCGCGGCTGGTACTGCTGTTCAGCGGCAAGAGGAAATCCGGGAAGGACTTCGTGACCGAGGCGCTGCAG AGCAGGCCCGACAACAAGCTCAAATACGTCACCAAATGGCAGAGGACAGCAAAGCAGATTACTCATCCATTCTCCAGAAATTCAACCATG AGCAGCATGAATATTACCATACTCACATCCCCAACATCTTCCAGAAAATACAAGAGATGGAGGAAAGGAGGATTGTGAGAATGGGAGAGT CCATGAAGACATATGCAGAGGTTGATCGGCAGGTGATCCCAATCATTGGGAAGTGCCTGGATGGAATAGTAAAAGCAGCCGAATCAATTG ATCAGAAAAATGATTCACAGCTGGTAATAGAAGCTTATAAATCAGGGTTTGAGCCTCCTGGAGACATTGAATTTGAGGATTACACTCAGC CAATGAAGCGCACTGTGTCAGATAACAGCCTTTCAAATTCCAGAGGAGAAGGCAAACCAGACCTCAAATTTGGTGGCAAATCCAAAGGAA AGTTATGGCCGTTCATCAAAAAAAATAAGTCTCCCAAGCAGCAAAAGGAACCCCTCTCCCATCGCTTCAACGAGTTCATGACCTCCAAAC CCAAAATCCACTGCTTCAGGAGCCTAAAGCGTGGGCTTTCTCTCAAGCTGGGTGCAACACCGGAGGATTTCAGCAACCTCCCACCTGAAC AAAGAAGGAAAAAGCTGCAGCAGAAAGTCGATGAGTTAAATAAAGAAATTCAGAAGGAGATGGATCAAAGAGATGCCATAACAAAAATGA AAGATGTCTACCTAAAGAATCCTCAGATGGGAGACCCAGCCAGTTTGGATCACAAATTAGCAGAAGTCAGCCAAAATATAGAGAAACTGC GAGTAGAGACCCAGAAATTTGAGGCCTGGCTGGCTGAGGTTGAAGGCCGGCTCCCAGCACGCAGCGAGCAGGCGCGCCGGCAGAGCGGAC TGTACGACAGCCAGAACCCACCCACAGTCAACAACTGCGCCCAGGACCGTGAGAGCCCAGATGGCAGTTACACAGAGGAGCAGAGTCAGG AGAGTGAGATGAAGGTGCTGGCCACGGATTTTGACGACGAGTTTGATGATGAGGAGCCCCTCCCTGCCATAGGGACGTGCAAAGCTCTCT ACACATTTGAAGGTCAGAATGAAGGAACGATTTCCGTAGTTGAAGGAGAAACATTGTATGTCATAGAGGAAGACAAAGGCGATGGCTGGA CCCGCATTCGGAGAAATGAAGATGAAGAGGGTTATGTCCCCACTTCATATGTCGAAGTCTGTTTGGACAAAAATGCCAAAGGTGCTAAGA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_PMVK_ENST00000368467_chr1_154909067_-_FNBP1_ENST00000446176_chr9_132691974_-_5094nt GAAGGTTCTGGGCGGGGCTGGACTGTTCTAAGTGAGTTCGGGTGGGGGAGCTTCACGAGGGGAGGCTGCTCTGTGAAGGAACCGCCTTTC TCTCCGCGTGTCTCACCCTTTTCTCCCCATATCTGTTTGGACATGAGCTGAGGGCACGGTCGCGGGCGGTCAGCCCTGTTCGCAGCTACG GCGAGGAGGGGCGCGATTGTTCCTTGTTGCCGCTCCGCTTAGTGGCCGCGTCCATTCCGCGCGGTGTCCCGATTTTAGGGGTAGGGAGAA GTGTCAGCTTCAGGCATCGCGAGGCGTGGCGGCCCCATGGCCCCGCTGGGAGGCGCCCCGCGGCTGGTACTGCTGTTCAGCGGCAAGAGG AAATCCGGGAAGGACTTCGTGACCGAGGCGCTGCAGAGCAGGCCCGACAACAAGCTCAAATACGTCACCAAATGGCAGAGGACAGCAAAG CAGATTACTCATCCATTCTCCAGAAATTCAACCATGAGCAGCATGAATATTACCATACTCACATCCCCAACATCTTCCAGAAAATACAAG AGATGGAGGAAAGGAGGATTGTGAGAATGGGAGAGTCCATGAAGACATATGCAGAGGTTGATCGGCAGGTGATCCCAATCATTGGGAAGT GCCTGGATGGAATAGTAAAAGCAGCCGAATCAATTGATCAGAAAAATGATTCACAGCTGGTAATAGAAGCTTATAAATCAGGGTTTGAGC CTCCTGGAGACATTGAATTTGAGGATTACACTCAGCCAATGAAGCGCACTGTGTCAGATAACAGCCTTTCAAATTCCAGAGGAGAAGGCA AACCAGACCTCAAATTTGGTGGCAAATCCAAAGGAAAGTTATGGCCGTTCATCAAAAAAAATAAGCTTATGTCCCTTTTAACATCCCCCC ATCAGCCTCCCCCTCCCCCTCCTGCCTCTGCCTCACCCTCTGCTGTTCCCAACGGCCCCCAGTCTCCCAAGCAGCAAAAGGAACCCCTCT CCCATCGCTTCAACGAGTTCATGACCTCCAAACCCAAAATCCACTGCTTCAGGAGCCTAAAGCGTGGGCTTTCTCTCAAGCTGGGTGCAA CACCGGAGGATTTCAGCAACCTCCCACCTGAACAAAGAAGGAAAAAGCTGCAGCAGAAAGTCGATGAGTTAAATAAAGAAATTCAGAAGG AGATGGATCAAAGAGATGCCATAACAAAAATGAAAGATGTCTACCTAAAGAATCCTCAGATGGGAGACCCAGCCAGTTTGGATCACAAAT TAGCAGAAGTCAGCCAAAATATAGAGAAACTGCGAGTAGAGACCCAGAAATTTGAGGCCTGGCTGGCTGAGGTTGAAGGCCGGCTCCCAG CACGCAGCGAGCAGGCGCGCCGGCAGAGCGGACTGTACGACAGCCAGAACCCACCCACAGTCAACAACTGCGCCCAGGACCGTGAGAGCC CAGATGGCAGTTACACAGAGGAGCAGAGTCAGGAGAGTGAGATGAAGGTGCTGGCCACGGATTTTGACGACGAGTTTGATGATGAGGAGC CCCTCCCTGCCATAGGGACGTGCAAAGCTCTCTACACATTTGAAGGTCAGAATGAAGGAACGATTTCCGTAGTTGAAGGAGAAACATTGT ATGTCATAGAGGAAGACAAAGGCGATGGCTGGACCCGCATTCGGAGAAATGAAGATGAAGAGGGTTATGTCCCCACTTCATATGTCGAAG TCTGTTTGGACAAAAATGCCAAAGATTCCTAGAGGGGAGTGCCTGCGAGCCTCGGGTGAGCCTTCCTGGAGGAGCCTCCGTCTGCTTGTT CCCACAGGCCTCCAGCGCCCTGCCCTGTGGACAGCCCACCCCTCCGCAGCCCCATCCCTGCGGGGCGGTCTCTCTCTCTCTCCAGCATGC TCCCTGCGGCCCTGCCCTCCCGCCCAGCCCGGGCCACCTCGTGGGGGACAAGTCTCGCCAGCGCCCACCCCCATGGCTCGGGTCAGTCCT CATCGCTCCCCCTCCCCACCCCGCGCAGGCCACTGAGACGGTGGGACACACGCCCCTACCTGCTCCTTCCTGGGCCCTCAGTCCACCCGG GCTCGTCCTGGCAGCCCTTCCGCGCTTCACACAGTGCCTTTTGTGAAAGTGTCATCACGGGTCCCCTGAGGAGACAAGGCAGGTCCAGCG CACATCAGGCGGACTGAGCACTCGATGTCATCCGTGTCGATGTCATCCGTGTGTCCCAGACTGTCTGCTGTAGAAAACACTTCCTCCTCT CCTGAGTCTGTGAAGTCCTCAGTGGTCCTTTTTGGATTCTAGGCTTGCACCTCATACTAAACATTGACCCTTTCACTATGCCCTCAACCT GGGAGCATCTGGCAGGCAGGGGGGCAGGTACACACACACCCACAGGCACACCCACCAGTACACACGCGTGCGCATACACACATTTTGGTT TGACGCCCTGTTTTCAGTGGCCTGGGGAGGTCCACACTGGAAGTCGAATTCCAGCTCGCCTTGTTGACTCGCCTGTGTCCACCGGCCATG AGGAGCCCACGCCTGTCCTCCCCATCACTTTCCTGTCCCTGAGAACTGTAGATCATGCGCTTGTGAGCGAGGCCCTCCCCTCTGCACCAG CTCATTGCAAAGCGAACATCCTCTCCTTTCCAGGAGCCCCAGGATTAGCATCTGAAAAGGGTAGCACTTCCTTTTTTGTTGTTGTTTTTT TTTTTTTTTTGAGACGGGAGTCTCGCTCTATTGTTCAGACTGGAGTGCAGTGGCATGATCTCGGCTCACTACAACCTCCACCTCCTGGGT TCCAGCGATTCTCCTGCCTCAGCCTCCCAAATAGCTGTGATTACAGGCGTGCACCACCACGCCCGGCTAATGTTTGTATTTTTAGTAGAG ACAGGGTTTCACCGTGTTGGTCAGGCTGGTCTCAAACTCCTGACCTCAGGTGATCCGCCCGCCTCAGCCTCCCAAAGTGCTGAGATTACA GGTGTGAGCTACCGCACCCCGCCGAGGTTAGCACTTTCATCACCAAAGACCCCGTGCCTCTCGTGGTCCTTTGAGGGATCCCGCCGCCAC CACCCTTGTATTTTATCACGTGCTCTTCAGGGCATGTGGAATTCGTTGAGTTTGCTTTTAGAGCCAAGTTTCTTTCCCTGTGTGGGTTTT TGAGGAAAACCTGAGGTCCCCTAATCTGTGGCCACCACCCCCCCCCCCCGCCACGCCTTAGAGCAGAGCAGCCCCTCCTCTCATTTGGTG CAGAAACAGTCAAGAGGAACCATTGGCCTAGAGCTCCTGTGACCGAGAGCGCCACGGAAGCCTGGGGATGACGTCGGGCAGCTTTATTCT TTGCTTGGCTTTGGTAACTAGGTGGTCCCCTCAAGCATCCTCAGTTCCTCTTGCTGTTTATGAATCTAAGACAAGGAAGTCCTATAGAAG CCAAAGGGACAGGGACGGAAAGGACAGGTCCCAAGGGATGGGGCTGTCTTTACTTGTGGAAACCAGGAAATTGCTCCTCTCAGCCAACCA AGGTTGACCACACACCACCCTTCCGGAGCAGCTCAGTCAGCCCTCGGGGACGAGAAACCACAAGCGCAGAGACGCTGAGGCCCAGGCAGG TGAAGAGGAAGTGGCTTTGGGTTTTTAAAGTAGGTGAGCGTGAGCCTCTCTGACTGCTTCTTCCCCGGGGGGGACTGCAAACCGCTCAGG GTTGCGGCAGAGCCATGGACTTCCGGTCCCTGCAACGGGTGACCTAAGCGTGGTGCACCCATCAGTCACGCAGGAGGACTGACTTGACAG ACGAAAGACAAGCCCGGATGACACAGGGTGAGAAGAGTCAGGGCCGCACCTCTGTCCCTGCAAACCAACAGGTGCATGGTGAGTGTGGCA GTCCCCACAGCTCCACAATGGGCTCCCCCGCCAACGGGGACGACAGGGATCTTCAGGAACTTCTGACCTCACCAAGTCAAGTGGACCACT CTCCACTCCACGAGGATGTGAAACGGTTCTTTAAAATGGGATTTTAGAGCCTCGGGAATGCATGTGCGTCACATCTTTCATATTATGGGT CAGGATAGATTCATTTCTTGCAACATAGTGGAAAAGATATAAGCTGCAGTAATTTGCTCTTTGAATGACCGTCACCCCCAGTATAGGATA TGCTTGTATCCCCCCGTCACTCCTCCGCCTGTTTTTTAAACTTTTCCACCACCTGCGTCCAAAAAGAATGTTATAGCGAGTGCTCTTAAA TGTTGAACCTGGGTGTTGCTTCCGGGCCAGTCTGCGTGGCTCCATGAAAAGCTCACTGCTGCCCCAGCCGGGCTTCTTAGAGGAGGTCAG TTGTCCTATGTATCATCATTTACTCTGGGAATCCTACTGTGAAATCATGTCTGTATTTTTCTGGAGCAGTTCACATAGAGTAGAATGTGG AATTTCCCGTGAACGTCTCCTTCCTCCCCCGTATCTGCCGCCTGTCACTTCGCCACCGTGCTAGAATACTGTTGTGTTGTAAGATGACTA ATTTTAAAAGAACCTGCCCTGAAAAGTTCTTAGAAACGCAGTGAAAGGGAGGAACTTGTCCTTTACCCAGTTTTTCCTTTGTAGGATGGG AAAGTATAAAAAGGCACAGAAGGTTGTCATGGGCTGTTCCTTGGGGGTTTTTATCCTGCTCACCGTGGAGATAAGCCTGCGGCTTGTCTA ACCAGCGCAGCGCAAAGGTCTCGATGCCTTTTGGTAACATCCGTCATTGCAGAAGAAAGTTTACACGACGTCAAAAAGTGACGTTCATGC TAAGTGTTTTTCCAGAAATATTGGTTTCATGTTTCTTATTGGCTCTGCCTCCTGTGCTTATATCATCCAAAAACTTTTTAAAAAGGTCCA GAATTCTATTTTAACCTGATGTTGAGCACCTTTAAAATGTTCGTATGTGTGTTGCACTAATTCTAAACTTTGGAGGCATTTTGCTGTGTG AGGCCGATCGCCACTGTAAAGGTCCTAGAGTTGCCTGTTTGTCTCTGGAGATGGAATTAAACCAAATAAAGAGCTTCCACTGGAGGCTTG >In-frame_PMVK_ENST00000368467_chr1_154909067_-_FNBP1_ENST00000420781_chr9_132691974_-_5067nt GAAGGTTCTGGGCGGGGCTGGACTGTTCTAAGTGAGTTCGGGTGGGGGAGCTTCACGAGGGGAGGCTGCTCTGTGAAGGAACCGCCTTTC TCTCCGCGTGTCTCACCCTTTTCTCCCCATATCTGTTTGGACATGAGCTGAGGGCACGGTCGCGGGCGGTCAGCCCTGTTCGCAGCTACG GCGAGGAGGGGCGCGATTGTTCCTTGTTGCCGCTCCGCTTAGTGGCCGCGTCCATTCCGCGCGGTGTCCCGATTTTAGGGGTAGGGAGAA GTGTCAGCTTCAGGCATCGCGAGGCGTGGCGGCCCCATGGCCCCGCTGGGAGGCGCCCCGCGGCTGGTACTGCTGTTCAGCGGCAAGAGG AAATCCGGGAAGGACTTCGTGACCGAGGCGCTGCAGAGCAGGCCCGACAACAAGCTCAAATACGTCACCAAATGGCAGAGGACAGCAAAG CAGATTACTCATCCATTCTCCAGAAATTCAACCATGAGCAGCATGAATATTACCATACTCACATCCCCAACATCTTCCAGAAAATACAAG AGATGGAGGAAAGGAGGATTGTGAGAATGGGAGAGTCCATGAAGACATATGCAGAGGTTGATCGGCAGGTGATCCCAATCATTGGGAAGT GCCTGGATGGAATAGTAAAAGCAGCCGAATCAATTGATCAGAAAAATGATTCACAGCTGGTAATAGAAGCTTATAAATCAGGGTTTGAGC CTCCTGGAGACATTGAATTTGAGGATTACACTCAGCCAATGAAGCGCACTGTGTCAGATAACAGCCTTTCAAATTCCAGAGGAGAAGGCA AACCAGACCTCAAATTTGGTGGCAAATCCAAAGGAAAGTTATGGCCGTTCATCAAAAAAAATAAGCCTCCCCCTCCCCCTCCTGCCTCTG CCTCACCCTCTGCTGTTCCCAACGGCCCCCAGTCTCCCAAGCAGCAAAAGGAACCCCTCTCCCATCGCTTCAACGAGTTCATGACCTCCA AACCCAAAATCCACTGCTTCAGGAGCCTAAAGCGTGGGCATAGCCTCACTCTGCAGGGTGCAACACCGGAGGATTTCAGCAACCTCCCAC CTGAACAAAGAAGGAAAAAGCTGCAGCAGAAAGTCGATGAGTTAAATAAAGAAATTCAGAAGGAGATGGATCAAAGAGATGCCATAACAA AAATGAAAGATGTCTACCTAAAGAATCCTCAGATGGGAGACCCAGCCAGTTTGGATCACAAATTAGCAGAAGTCAGCCAAAATATAGAGA AACTGCGAGTAGAGACCCAGAAATTTGAGGCCTGGCTGGCTGAGGTTGAAGGCCGGCTCCCAGCACGCAGCGAGCAGGCGCGCCGGCAGA GCGGACTGTACGACAGCCAGAACCCACCCACAGTCAACAACTGCGCCCAGGACCGTGAGAGCCCAGATGGCAGTTACACAGAGGAGCAGA GTCAGGAGAGTGAGATGAAGGTGCTGGCCACGGATTTTGACGACGAGTTTGATGATGAGGAGCCCCTCCCTGCCATAGGGACGTGCAAAG CTCTCTACACATTTGAAGGTCAGAATGAAGGAACGATTTCCGTAGTTGAAGGAGAAACATTGTATGTCATAGAGGAAGACAAAGGCGATG GCTGGACCCGCATTCGGAGAAATGAAGATGAAGAGGGTTATGTCCCCACTTCATATGTCGAAGTCTGTTTGGACAAAAATGCCAAAGATT CCTAGAGGGGAGTGCCTGCGAGCCTCGGGTGAGCCTTCCTGGAGGAGCCTCCGTCTGCTTGTTCCCACAGGCCTCCAGCGCCCTGCCCTG TGGACAGCCCACCCCTCCGCAGCCCCATCCCTGCGGGGCGGTCTCTCTCTCTCTCCAGCATGCTCCCTGCGGCCCTGCCCTCCCGCCCAG CCCGGGCCACCTCGTGGGGGACAAGTCTCGCCAGCGCCCACCCCCATGGCTCGGGTCAGTCCTCATCGCTCCCCCTCCCCACCCCGCGCA GGCCACTGAGACGGTGGGACACACGCCCCTACCTGCTCCTTCCTGGGCCCTCAGTCCACCCGGGCTCGTCCTGGCAGCCCTTCCGCGCTT CACACAGTGCCTTTTGTGAAAGTGTCATCACGGGTCCCCTGAGGAGACAAGGCAGGTCCAGCGCACATCAGGCGGACTGAGCACTCGATG TCATCCGTGTCGATGTCATCCGTGTGTCCCAGACTGTCTGCTGTAGAAAACACTTCCTCCTCTCCTGAGTCTGTGAAGTCCTCAGTGGTC CTTTTTGGATTCTAGGCTTGCACCTCATACTAAACATTGACCCTTTCACTATGCCCTCAACCTGGGAGCATCTGGCAGGCAGGGGGGCAG GTACACACACACCCACAGGCACACCCACCAGTACACACGCGTGCGCATACACACATTTTGGTTTGACGCCCTGTTTTCAGTGGCCTGGGG AGGTCCACACTGGAAGTCGAATTCCAGCTCGCCTTGTTGACTCGCCTGTGTCCACCGGCCATGAGGAGCCCACGCCTGTCCTCCCCATCA CTTTCCTGTCCCTGAGAACTGTAGATCATGCGCTTGTGAGCGAGGCCCTCCCCTCTGCACCAGCTCATTGCAAAGCGAACATCCTCTCCT TTCCAGGAGCCCCAGGATTAGCATCTGAAAAGGGTAGCACTTCCTTTTTTGTTGTTGTTTTTTTTTTTTTTTTGAGACGGGAGTCTCGCT CTATTGTTCAGACTGGAGTGCAGTGGCATGATCTCGGCTCACTACAACCTCCACCTCCTGGGTTCCAGCGATTCTCCTGCCTCAGCCTCC CAAATAGCTGTGATTACAGGCGTGCACCACCACGCCCGGCTAATGTTTGTATTTTTAGTAGAGACAGGGTTTCACCGTGTTGGTCAGGCT GGTCTCAAACTCCTGACCTCAGGTGATCCGCCCGCCTCAGCCTCCCAAAGTGCTGAGATTACAGGTGTGAGCTACCGCACCCCGCCGAGG TTAGCACTTTCATCACCAAAGACCCCGTGCCTCTCGTGGTCCTTTGAGGGATCCCGCCGCCACCACCCTTGTATTTTATCACGTGCTCTT CAGGGCATGTGGAATTCGTTGAGTTTGCTTTTAGAGCCAAGTTTCTTTCCCTGTGTGGGTTTTTGAGGAAAACCTGAGGTCCCCTAATCT GTGGCCACCACCCCCCCCCCCCGCCACGCCTTAGAGCAGAGCAGCCCCTCCTCTCATTTGGTGCAGAAACAGTCAAGAGGAACCATTGGC CTAGAGCTCCTGTGACCGAGAGCGCCACGGAAGCCTGGGGATGACGTCGGGCAGCTTTATTCTTTGCTTGGCTTTGGTAACTAGGTGGTC CCCTCAAGCATCCTCAGTTCCTCTTGCTGTTTATGAATCTAAGACAAGGAAGTCCTATAGAAGCCAAAGGGACAGGGACGGAAAGGACAG GTCCCAAGGGATGGGGCTGTCTTTACTTGTGGAAACCAGGAAATTGCTCCTCTCAGCCAACCAAGGTTGACCACACACCACCCTTCCGGA GCAGCTCAGTCAGCCCTCGGGGACGAGAAACCACAAGCGCAGAGACGCTGAGGCCCAGGCAGGTGAAGAGGAAGTGGCTTTGGGTTTTTA AAGTAGGTGAGCGTGAGCCTCTCTGACTGCTTCTTCCCCGGGGGGGACTGCAAACCGCTCAGGGTTGCGGCAGAGCCATGGACTTCCGGT CCCTGCAACGGGTGACCTAAGCGTGGTGCACCCATCAGTCACGCAGGAGGACTGACTTGACAGACGAAAGACAAGCCCGGATGACACAGG GTGAGAAGAGTCAGGGCCGCACCTCTGTCCCTGCAAACCAACAGGTGCATGGTGAGTGTGGCAGTCCCCACAGCTCCACAATGGGCTCCC CCGCCAACGGGGACGACAGGGATCTTCAGGAACTTCTGACCTCACCAAGTCAAGTGGACCACTCTCCACTCCACGAGGATGTGAAACGGT TCTTTAAAATGGGATTTTAGAGCCTCGGGAATGCATGTGCGTCACATCTTTCATATTATGGGTCAGGATAGATTCATTTCTTGCAACATA GTGGAAAAGATATAAGCTGCAGTAATTTGCTCTTTGAATGACCGTCACCCCCAGTATAGGATATGCTTGTATCCCCCCGTCACTCCTCCG CCTGTTTTTTAAACTTTTCCACCACCTGCGTCCAAAAAGAATGTTATAGCGAGTGCTCTTAAATGTTGAACCTGGGTGTTGCTTCCGGGC CAGTCTGCGTGGCTCCATGAAAAGCTCACTGCTGCCCCAGCCGGGCTTCTTAGAGGAGGTCAGTTGTCCTATGTATCATCATTTACTCTG GGAATCCTACTGTGAAATCATGTCTGTATTTTTCTGGAGCAGTTCACATAGAGTAGAATGTGGAATTTCCCGTGAACGTCTCCTTCCTCC CCCGTATCTGCCGCCTGTCACTTCGCCACCGTGCTAGAATACTGTTGTGTTGTAAGATGACTAATTTTAAAAGAACCTGCCCTGAAAAGT TCTTAGAAACGCAGTGAAAGGGAGGAACTTGTCCTTTACCCAGTTTTTCCTTTGTAGGATGGGAAAGTATAAAAAGGCACAGAAGGTTGT CATGGGCTGTTCCTTGGGGGTTTTTATCCTGCTCACCGTGGAGATAAGCCTGCGGCTTGTCTAACCAGCGCAGCGCAAAGGTCTCGATGC CTTTTGGTAACATCCGTCATTGCAGAAGAAAGTTTACACGACGTCAAAAAGTGACGTTCATGCTAAGTGTTTTTCCAGAAATATTGGTTT CATGTTTCTTATTGGCTCTGCCTCCTGTGCTTATATCATCCAAAAACTTTTTAAAAAGGTCCAGAATTCTATTTTAACCTGATGTTGAGC ACCTTTAAAATGTTCGTATGTGTGTTGCACTAATTCTAAACTTTGGAGGCATTTTGCTGTGTGAGGCCGATCGCCACTGTAAAGGTCCTA GAGTTGCCTGTTTGTCTCTGGAGATGGAATTAAACCAAATAAAGAGCTTCCACTGGAGGCTTGTATTGACCTTGTAACTATATGTTAATC >In-frame_PMVK_ENST00000368467_chr1_154909067_-_FNBP1_ENST00000355681_chr9_132691974_-_1673nt GAAGGTTCTGGGCGGGGCTGGACTGTTCTAAGTGAGTTCGGGTGGGGGAGCTTCACGAGGGGAGGCTGCTCTGTGAAGGAACCGCCTTTC TCTCCGCGTGTCTCACCCTTTTCTCCCCATATCTGTTTGGACATGAGCTGAGGGCACGGTCGCGGGCGGTCAGCCCTGTTCGCAGCTACG GCGAGGAGGGGCGCGATTGTTCCTTGTTGCCGCTCCGCTTAGTGGCCGCGTCCATTCCGCGCGGTGTCCCGATTTTAGGGGTAGGGAGAA GTGTCAGCTTCAGGCATCGCGAGGCGTGGCGGCCCCATGGCCCCGCTGGGAGGCGCCCCGCGGCTGGTACTGCTGTTCAGCGGCAAGAGG AAATCCGGGAAGGACTTCGTGACCGAGGCGCTGCAGAGCAGGCCCGACAACAAGCTCAAATACGTCACCAAATGGCAGAGGACAGCAAAG CAGATTACTCATCCATTCTCCAGAAATTCAACCATGAGCAGCATGAATATTACCATACTCACATCCCCAACATCTTCCAGAAAATACAAG AGATGGAGGAAAGGAGGATTGTGAGAATGGGAGAGTCCATGAAGACATATGCAGAGGTTGATCGGCAGGTGATCCCAATCATTGGGAAGT GCCTGGATGGAATAGTAAAAGCAGCCGAATCAATTGATCAGAAAAATGATTCACAGCTGGTAATAGAAGCTTATAAATCAGGGTTTGAGC CTCCTGGAGACATTGAATTTGAGGATTACACTCAGCCAATGAAGCGCACTGTGTCAGATAACAGCCTTTCAAATTCCAGAGGAGAAGGCA AACCAGACCTCAAATTTGGTGGCAAATCCAAAGGAAAGTTATGGCCGTTCATCAAAAAAAATAAGTCTCCCAAGCAGCAAAAGGAACCCC TCTCCCATCGCTTCAACGAGTTCATGACCTCCAAACCCAAAATCCACTGCTTCAGGAGCCTAAAGCGTGGGCTTTCTCTCAAGCTGGGTG CAACACCGGAGGATTTCAGCAACCTCCCACCTGAACAAAGAAGGAAAAAGCTGCAGCAGAAAGTCGATGAGTTAAATAAAGAAATTCAGA AGGAGATGGATCAAAGAGATGCCATAACAAAAATGAAAGATGTCTACCTAAAGAATCCTCAGATGGGAGACCCAGCCAGTTTGGATCACA AATTAGCAGAAGTCAGCCAAAATATAGAGAAACTGCGAGTAGAGACCCAGAAATTTGAGGCCTGGCTGGCTGAGGTTGAAGGCCGGCTCC CAGCACGCAGCGAGCAGGCGCGCCGGCAGAGCGGACTGTACGACAGCCAGAACCCACCCACAGTCAACAACTGCGCCCAGGACCGTGAGA GCCCAGATGGCAGTTACACAGAGGAGCAGAGTCAGGAGAGTGAGATGAAGGTGCTGGCCACGGATTTTGACGACGAGTTTGATGATGAGG AGCCCCTCCCTGCCATAGGGACGTGCAAAGCTCTCTACACATTTGAAGGTCAGAATGAAGGAACGATTTCCGTAGTTGAAGGAGAAACAT TGTATGTCATAGAGGAAGACAAAGGCGATGGCTGGACCCGCATTCGGAGAAATGAAGATGAAGAGGGTTATGTCCCCACTTCATATGTCG |
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FusionGenePPI for PMVK_FNBP1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| PMVK | CENPH, PITPNA, RGS20, TBPL1, MPDU1, SSB, MLF2, RASGRF2, WDR92, ARL6IP6, MBD5, SCNM1, SLC25A35, SLC25A32, SNRNP27, FGB, GTF2E2, C4orf26, SETD3, NPPA, FSD1, FYTTD1, NKD2, RDH12, SDHA, MCPH1 | FNBP1 | TNKS, AKAP9, FNBP1, DNM1, EGF, TF, SNX2, FASLG, ARHGAP17, TUBB, HSPA1A, WAS, GABARAP, ITSN1, ELAVL1, WASL, DNM2, SHMT2, NXF1, FCHO1, PPP2CA, MYO1E, SF3A1, TMEM17, RBPJ, TRIM25 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| Tgene | FNBP1 | chr1:154909067 | chr9:132691974 | ENST00000355681 | - | 5 | 16 | 550_617 | 171 | 593 | ARHGAP17%2C DAAM1%2C DIAPH1 and DIAPH2 |
| Tgene | FNBP1 | chr1:154909067 | chr9:132691974 | ENST00000446176 | - | 5 | 17 | 550_617 | 171 | 618 | ARHGAP17%2C DAAM1%2C DIAPH1 and DIAPH2 |
| Tgene | FNBP1 | chr1:154909067 | chr9:132691974 | ENST00000355681 | - | 5 | 16 | 535_617 | 171 | 593 | DNM1 and DNM3 |
| Tgene | FNBP1 | chr1:154909067 | chr9:132691974 | ENST00000446176 | - | 5 | 17 | 535_617 | 171 | 618 | DNM1 and DNM3 |
| Tgene | FNBP1 | chr1:154909067 | chr9:132691974 | ENST00000355681 | - | 5 | 16 | 553_609 | 171 | 593 | DNM2 and WASL |
| Tgene | FNBP1 | chr1:154909067 | chr9:132691974 | ENST00000446176 | - | 5 | 17 | 553_609 | 171 | 618 | DNM2 and WASL |
| Tgene | FNBP1 | chr1:154909067 | chr9:132691974 | ENST00000355681 | - | 5 | 16 | 553_610 | 171 | 593 | FASLG |
| Tgene | FNBP1 | chr1:154909067 | chr9:132691974 | ENST00000446176 | - | 5 | 17 | 553_610 | 171 | 618 | FASLG |
| Tgene | FNBP1 | chr1:154909067 | chr9:132691974 | ENST00000355681 | - | 5 | 16 | 495_617 | 171 | 593 | PDE6G |
| Tgene | FNBP1 | chr1:154909067 | chr9:132691974 | ENST00000446176 | - | 5 | 17 | 495_617 | 171 | 618 | PDE6G |
| Tgene | FNBP1 | chr1:154909067 | chr9:132691974 | ENST00000355681 | - | 5 | 16 | 400_552 | 171 | 593 | RND2 |
| Tgene | FNBP1 | chr1:154909067 | chr9:132691974 | ENST00000446176 | - | 5 | 17 | 400_552 | 171 | 618 | RND2 |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Tgene | FNBP1 | chr1:154909067 | chr9:132691974 | ENST00000355681 | - | 5 | 16 | 1_335 | 171 | 593 | microtubules |
| Tgene | FNBP1 | chr1:154909067 | chr9:132691974 | ENST00000446176 | - | 5 | 17 | 1_335 | 171 | 618 | microtubules |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for PMVK_FNBP1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for PMVK_FNBP1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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