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Fusion gene ID: 27813 |
FusionGeneSummary for PMS2_DNAH11 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PMS2_DNAH11 | Fusion gene ID: 27813 | Hgene | Tgene | Gene symbol | PMS2 | DNAH11 | Gene ID | 5395 | 8701 |
| Gene name | PMS1 homolog 2, mismatch repair system component | dynein axonemal heavy chain 11 | |
| Synonyms | HNPCC4|MLH4|PMS2CL|PMSL2 | CILD7|DNAHBL|DNAHC11|DNHBL|DPL11 | |
| Cytomap | 7p22.1 | 7p15.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | mismatch repair endonuclease PMS2DNA mismatch repair protein PMS2PMS1 homolog 2, mismatch repair proteinPMS1 protein homolog 2PMS2 postmeiotic segregation increased 2postmeiotic segregation increased 2 nirs variant 6 | dynein heavy chain 11, axonemalaxonemal beta dynein heavy chain 11axonemal dynein heavy chain 11ciliary dynein heavy chain 11dynein, axonemal, heavy polypeptide 11dynein, ciliary, heavy chain 11 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | P54278 | Q96DT5 | |
| Ensembl transtripts involved in fusion gene | ENST00000265849, ENST00000441476, ENST00000382321, ENST00000406569, ENST00000469652, | ENST00000409508, ENST00000328843, ENST00000465593, | |
| Fusion gene scores | * DoF score | 3 X 1 X 3=9 | 4 X 4 X 4=64 |
| # samples | 3 | 4 | |
| ** MAII score | log2(3/9*10)=1.73696559416621 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(4/64*10)=-0.678071905112638 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: PMS2 [Title/Abstract] AND DNAH11 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | PMS2 | GO:0006298 | mismatch repair | 10871409|23709753 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LGG | TCGA-E1-A7Z2-01A | PMS2 | chr7 | 6048628 | - | DNAH11 | chr7 | 21813384 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000265849 | ENST00000409508 | PMS2 | chr7 | 6048628 | - | DNAH11 | chr7 | 21813384 | + |
| In-frame | ENST00000265849 | ENST00000328843 | PMS2 | chr7 | 6048628 | - | DNAH11 | chr7 | 21813384 | + |
| 5CDS-intron | ENST00000265849 | ENST00000465593 | PMS2 | chr7 | 6048628 | - | DNAH11 | chr7 | 21813384 | + |
| intron-3CDS | ENST00000441476 | ENST00000409508 | PMS2 | chr7 | 6048628 | - | DNAH11 | chr7 | 21813384 | + |
| intron-3CDS | ENST00000441476 | ENST00000328843 | PMS2 | chr7 | 6048628 | - | DNAH11 | chr7 | 21813384 | + |
| intron-intron | ENST00000441476 | ENST00000465593 | PMS2 | chr7 | 6048628 | - | DNAH11 | chr7 | 21813384 | + |
| In-frame | ENST00000382321 | ENST00000409508 | PMS2 | chr7 | 6048628 | - | DNAH11 | chr7 | 21813384 | + |
| In-frame | ENST00000382321 | ENST00000328843 | PMS2 | chr7 | 6048628 | - | DNAH11 | chr7 | 21813384 | + |
| 5CDS-intron | ENST00000382321 | ENST00000465593 | PMS2 | chr7 | 6048628 | - | DNAH11 | chr7 | 21813384 | + |
| In-frame | ENST00000406569 | ENST00000409508 | PMS2 | chr7 | 6048628 | - | DNAH11 | chr7 | 21813384 | + |
| In-frame | ENST00000406569 | ENST00000328843 | PMS2 | chr7 | 6048628 | - | DNAH11 | chr7 | 21813384 | + |
| 5CDS-intron | ENST00000406569 | ENST00000465593 | PMS2 | chr7 | 6048628 | - | DNAH11 | chr7 | 21813384 | + |
| 5UTR-3CDS | ENST00000469652 | ENST00000409508 | PMS2 | chr7 | 6048628 | - | DNAH11 | chr7 | 21813384 | + |
| 5UTR-3CDS | ENST00000469652 | ENST00000328843 | PMS2 | chr7 | 6048628 | - | DNAH11 | chr7 | 21813384 | + |
| 5UTR-intron | ENST00000469652 | ENST00000465593 | PMS2 | chr7 | 6048628 | - | DNAH11 | chr7 | 21813384 | + |
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FusionProtFeatures for PMS2_DNAH11 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| PMS2 | DNAH11 |
| Component of the post-replicative DNA mismatch repairsystem (MMR). Heterodimerizes with MLH1 to form MutL alpha. DNArepair is initiated by MutS alpha (MSH2-MSH6) or MutS beta (MSH2-MSH3) binding to a dsDNA mismatch, then MutL alpha is recruited tothe heteroduplex. Assembly of the MutL-MutS-heteroduplex ternarycomplex in presence of RFC and PCNA is sufficient to activateendonuclease activity of PMS2. It introduces single-strand breaksnear the mismatch and thus generates new entry points for theexonuclease EXO1 to degrade the strand containing the mismatch.DNA methylation would prevent cleavage and therefore assure thatonly the newly mutated DNA strand is going to be corrected. MutLalpha (MLH1-PMS2) interacts physically with the clamp loadersubunits of DNA polymerase III, suggesting that it may play a roleto recruit the DNA polymerase III to the site of the MMR. Alsoimplicated in DNA damage signaling, a process which induces cellcycle arrest and can lead to apoptosis in case of major DNAdamages. {ECO:0000269|PubMed:16873062,ECO:0000269|PubMed:18206974, ECO:0000269|PubMed:23709753}. | Force generating protein of respiratory cilia. Producesforce towards the minus ends of microtubules. Dynein has ATPaseactivity; the force-producing power stroke is thought to occur onrelease of ADP. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >DNAH11 | chr7:6048628 | chr7:21813384 | ENST00000328843 | + | 55 | 83 | 3072_3136 | 3041 | 4524 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >DNAH11 | chr7:6048628 | chr7:21813384 | ENST00000328843 | + | 55 | 83 | 3312_3403 | 3041 | 4524 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >DNAH11 | chr7:6048628 | chr7:21813384 | ENST00000328843 | + | 55 | 83 | 3668_3703 | 3041 | 4524 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >DNAH11 | chr7:6048628 | chr7:21813384 | ENST00000328843 | + | 55 | 83 | 3072_3403 | 3041 | 4524 | Region | Stalk |
| Tgene | >DNAH11 | chr7:6048628 | chr7:21813384 | ENST00000328843 | + | 55 | 83 | 3459_3686 | 3041 | 4524 | Region | AAA 5 |
| Tgene | >DNAH11 | chr7:6048628 | chr7:21813384 | ENST00000328843 | + | 55 | 83 | 3896_4122 | 3041 | 4524 | Region | AAA 6 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | DNAH11 | chr7:6048628 | chr7:21813384 | ENST00000328843 | + | 55 | 83 | 1274_1327 | 3041 | 4524 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | DNAH11 | chr7:6048628 | chr7:21813384 | ENST00000328843 | + | 55 | 83 | 1893_1900 | 3041 | 4524 | Nucleotide binding | ATP |
| Tgene | DNAH11 | chr7:6048628 | chr7:21813384 | ENST00000328843 | + | 55 | 83 | 2174_2181 | 3041 | 4524 | Nucleotide binding | ATP |
| Tgene | DNAH11 | chr7:6048628 | chr7:21813384 | ENST00000328843 | + | 55 | 83 | 2510_2517 | 3041 | 4524 | Nucleotide binding | ATP |
| Tgene | DNAH11 | chr7:6048628 | chr7:21813384 | ENST00000328843 | + | 55 | 83 | 2855_2862 | 3041 | 4524 | Nucleotide binding | ATP |
| Tgene | DNAH11 | chr7:6048628 | chr7:21813384 | ENST00000328843 | + | 55 | 83 | 1855_2076 | 3041 | 4524 | Region | AAA 1 |
| Tgene | DNAH11 | chr7:6048628 | chr7:21813384 | ENST00000328843 | + | 55 | 83 | 1_1854 | 3041 | 4524 | Region | Stem |
| Tgene | DNAH11 | chr7:6048628 | chr7:21813384 | ENST00000328843 | + | 55 | 83 | 2136_2366 | 3041 | 4524 | Region | AAA 2 |
| Tgene | DNAH11 | chr7:6048628 | chr7:21813384 | ENST00000328843 | + | 55 | 83 | 2472_2719 | 3041 | 4524 | Region | AAA 3 |
| Tgene | DNAH11 | chr7:6048628 | chr7:21813384 | ENST00000328843 | + | 55 | 83 | 2817_3066 | 3041 | 4524 | Region | AAA 4 |
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FusionGeneSequence for PMS2_DNAH11 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_PMS2_ENST00000265849_chr7_6048628_-_DNAH11_ENST00000409508_chr7_21813384_+_1490aa MERAESSSQCTKTLLAFSWHMFTPLXMKXVPDITRMREDTTIPPQRVFXNKYHCLRTCXRRSKMRYPRKKNAWXTASKSXKPQPLRWEIX KPDLPLKKPSCNXEIMMPKLXSQRSAFRRRKXAGKRPSLMLRSERXQPFRLKCSRNRENVKLTYSRLSLHWWLLQLHSIHSTGSTSVSXK PFPTLPSQLPMLLQPXWSFWLLGEECPKTEVGKQLKSSWERLMIFCKHXLTMTKSTFQRTVXKWXMNTIXKTQSLIQTXFEPNLLQQLAC VPGSSTSLNSMRSTVMWSQNAKHXPKQTXNWLQLLKNXRLSGKSLWIWIEIXADSRLHLKKQQLRKSGVKKRXTKPTKPSNXLTDLSRNL RQRRFAGVNPLSPLKLKRRHSVEMFFSRRHLCLTSDPSQGSIARSWCTASGFPFFNRRFPFHXPKAWTXYPCXRMMLQLPPGITKDCPVT ECPPKMPLSXHTVSAGLWXXIPSNRELSGSRISMEWTXKSHIWARKGFXMPLKLLWPLVMSSXLKISRKRXIQSWIHYLAGTQLKKESIS GLEIKNVNLTRTFALSFTQNWQILTISRNYKLRQLSSISQSQKMVXKPSCWQRLSVLKGQIWRNLSWYXQSTKMILKLSSSIWKTISFCA FLRQREAFWMTPNWXRDWRQQRPPWQRXSTRXLKPKKMKEKSTRPENVTDQWQQEHLFFILLLMTSKKSTPSTNSLXRLLTCCSTERSSR LTRWKTCRDASLSXWRASPMLSSSTPARRCLRRTSSPSCPRWLFRFCXERKRXTLLNWISCFDSQLNTLIXVPLTSXLLSHGVLSRQLPS WKNFEAXTEMWKDLPSSGGSGXNPSVQKKKNYLKNGRRKVXYRSXFFXEQCALTEXRMLSEILXRKNWVRSMWRGPDWTXLKHSKKAAQP PPYSSSCLRGXMPLKTWRFLAKDLALQLTLENSTMCLXDKVRRRWQKWPWRKLPKEDTGSSSKMFIWXPSGXEPWRSSLKDSAKEATEIT GFSXVLSLHLHQMSISSLKDSWKIPLRSLMNPQQGCWPICMPPCTTLIRIHLKYAPRSRSLKASFFLSATSTPVLLGDXGLAPRAGAEAI LLILETSPFVPVSSTTTXRQTLKSHGKISVISLVRSCMEATSQMTGIANCVGCIXKNSXIHLXLKMNXCWHQVLLPHPTXIMQATTSTXR RCFLQKARHCMASTQMLKXNSXQXHPTLSSELCWRCSPGMHSVVMNWGSLQKKRLRMSWMTFWRNFQKSSTWQRXCKKIQIEAHMFLFAS KNVRGXIFSFGKYVYHLNNWTLVXRGNWHYLLLWKPSSLHXVMTRYQTLGANWLILLLMAXPSGSMTSSCDAENSILGHKTLPFRLSCGS PASSTLSPSXLQSCRRWLEKMSGPWIKRAXLLMLPKKQRKIMDTRQGKVHTSTDSSWRAPAGTPKQEPLLKPVSRSWHALCRSSLQKPPP >In-frame_PMS2_ENST00000265849_chr7_6048628_-_DNAH11_ENST00000328843_chr7_21813384_+_1490aa MERAESSSQCTKTLLAFSWHMFTPLXMKXVPDITRMREDTTIPPQRVFXNKYHCLRTCXRRSKMRYPRKKNAWXTASKSXKPQPLRWEIX KPDLPLKKPSCNXEIMMPKLXSQRSAFRRRKXAGKRPSLMLRSERXQPFRLKCSRNRENVKLTYSRLSLHWWLLQLHSIHSTGSTSVSXK PFPTLPSQLPMLLQPXWSFWLLGEECPKTEVGKQLKSSWERLMIFCKHXLTMTKSTFQRTVXKWXMNTIXKTQSLIQTXFEPNLLQQLAC VPGSSTSLNSMRSTVMWSQNAKHXPKQTXNWLQLLKNXRLSGKSLWIWIEIXADSRLHLKKQQLRKSGVKKRXTKPTKPSNXLTDLSRNL RQRRFAGVNPLSPLKLKRRHSVEMFFSRRHLCLTSDPSQGSIARSWCTASGFPFFNRRFPFHXPKAWTXYPCXRMMLQLPPGITKDCPVT ECPPKMPLSXHTVSAGLWXXIPSNRELSGSRISMEWTXKSHIWARKGFXMPLKLLWPLVMSSXLKISRKRXIQSWIHYLAGTQLKKESIS GLEIKNVNLTRTFALSFTQNWQILTISRNYKLRQLSSISQSQKMVXKPSCWQRLSVLKGQIWRNLSWYXQSTKMILKLSSSIWKTISFCA FLRQREAFWMTPNWXRDWRQQRPPWQRXSTRXLKPKKMKEKSTRPENVTDQWQQEHLFFILLLMTSKKSTPSTNSLXRLLTCCSTERSSR LTRWKTCRDASLSXWRASPMLSSSTPARRCLRRTSSPSCPRWLFRFCXERKRXTLLNWISCFDSQLNTLIXVPLTSXLLSHGVLSRQLPS WKNFEAXTEMWKDLPSSGGSGXNPSVQKKKNYLKNGRRKVXYRSXFFXEQCALTEXRMLSEILXRKNWVRSMWRGPDWTXLKHSKKAAQP PPYSSSCLRGXMPLKTWRFLAKDLALQLTLENSTMCLXDKVRRRWQKWPWRKLPKEDTGSSSKMFIWXPSGXEPWRSSLKDSAKEATEIT GFSXVLSLHLHQMSISSLKDSWKIPLRSLMNPQQGCWPICMPPCTTLIRIHLKYAPRSRSLKASFFLSATSTPVLLGDXGLAPRAGAEAI LLILETSPFVPVSSTTTXRQTLKSHGKISVISLVRSCMEATSQMTGIANCVGCIXKNSXIHLXLKMNXCWHQVLLPHPTXIMQATTSTXR RCFLQKARHCMASTQMLKXNSXQXHPTLSSELCWRCSPGMHSVVMNWGSLQKKRLRMSWMTFWRNFQKSSTWQRXCKKIQIEAHMFLFAS KNVRGXIFSFGKYVYHLNNWTLVXRGNWHYLLLWKPSSLHXVMTRYQTLGANWLILLLMAXPSGSMTSSCDAENSILGHKTLPFRLSCGS PASSTLSPSXLQSCRRWLEKMSGPWIKRAXLLMLPKKQRKIMDTRQGKVHTSTDSSWRAPAGTPKQEPLLKPVSRSWHALCRSSLQKPPP >In-frame_PMS2_ENST00000382321_chr7_6048628_-_DNAH11_ENST00000409508_chr7_21813384_+_1490aa MERAESSSQCTKTLLAFSWHMFTPLXMKXVPDITRMREDTTIPPQRVFXNKYHCLRTCXRRSKMRYPRKKNAWXTASKSXKPQPLRWEIX KPDLPLKKPSCNXEIMMPKLXSQRSAFRRRKXAGKRPSLMLRSERXQPFRLKCSRNRENVKLTYSRLSLHWWLLQLHSIHSTGSTSVSXK PFPTLPSQLPMLLQPXWSFWLLGEECPKTEVGKQLKSSWERLMIFCKHXLTMTKSTFQRTVXKWXMNTIXKTQSLIQTXFEPNLLQQLAC VPGSSTSLNSMRSTVMWSQNAKHXPKQTXNWLQLLKNXRLSGKSLWIWIEIXADSRLHLKKQQLRKSGVKKRXTKPTKPSNXLTDLSRNL RQRRFAGVNPLSPLKLKRRHSVEMFFSRRHLCLTSDPSQGSIARSWCTASGFPFFNRRFPFHXPKAWTXYPCXRMMLQLPPGITKDCPVT ECPPKMPLSXHTVSAGLWXXIPSNRELSGSRISMEWTXKSHIWARKGFXMPLKLLWPLVMSSXLKISRKRXIQSWIHYLAGTQLKKESIS GLEIKNVNLTRTFALSFTQNWQILTISRNYKLRQLSSISQSQKMVXKPSCWQRLSVLKGQIWRNLSWYXQSTKMILKLSSSIWKTISFCA FLRQREAFWMTPNWXRDWRQQRPPWQRXSTRXLKPKKMKEKSTRPENVTDQWQQEHLFFILLLMTSKKSTPSTNSLXRLLTCCSTERSSR LTRWKTCRDASLSXWRASPMLSSSTPARRCLRRTSSPSCPRWLFRFCXERKRXTLLNWISCFDSQLNTLIXVPLTSXLLSHGVLSRQLPS WKNFEAXTEMWKDLPSSGGSGXNPSVQKKKNYLKNGRRKVXYRSXFFXEQCALTEXRMLSEILXRKNWVRSMWRGPDWTXLKHSKKAAQP PPYSSSCLRGXMPLKTWRFLAKDLALQLTLENSTMCLXDKVRRRWQKWPWRKLPKEDTGSSSKMFIWXPSGXEPWRSSLKDSAKEATEIT GFSXVLSLHLHQMSISSLKDSWKIPLRSLMNPQQGCWPICMPPCTTLIRIHLKYAPRSRSLKASFFLSATSTPVLLGDXGLAPRAGAEAI LLILETSPFVPVSSTTTXRQTLKSHGKISVISLVRSCMEATSQMTGIANCVGCIXKNSXIHLXLKMNXCWHQVLLPHPTXIMQATTSTXR RCFLQKARHCMASTQMLKXNSXQXHPTLSSELCWRCSPGMHSVVMNWGSLQKKRLRMSWMTFWRNFQKSSTWQRXCKKIQIEAHMFLFAS KNVRGXIFSFGKYVYHLNNWTLVXRGNWHYLLLWKPSSLHXVMTRYQTLGANWLILLLMAXPSGSMTSSCDAENSILGHKTLPFRLSCGS PASSTLSPSXLQSCRRWLEKMSGPWIKRAXLLMLPKKQRKIMDTRQGKVHTSTDSSWRAPAGTPKQEPLLKPVSRSWHALCRSSLQKPPP >In-frame_PMS2_ENST00000382321_chr7_6048628_-_DNAH11_ENST00000328843_chr7_21813384_+_1490aa MERAESSSQCTKTLLAFSWHMFTPLXMKXVPDITRMREDTTIPPQRVFXNKYHCLRTCXRRSKMRYPRKKNAWXTASKSXKPQPLRWEIX KPDLPLKKPSCNXEIMMPKLXSQRSAFRRRKXAGKRPSLMLRSERXQPFRLKCSRNRENVKLTYSRLSLHWWLLQLHSIHSTGSTSVSXK PFPTLPSQLPMLLQPXWSFWLLGEECPKTEVGKQLKSSWERLMIFCKHXLTMTKSTFQRTVXKWXMNTIXKTQSLIQTXFEPNLLQQLAC VPGSSTSLNSMRSTVMWSQNAKHXPKQTXNWLQLLKNXRLSGKSLWIWIEIXADSRLHLKKQQLRKSGVKKRXTKPTKPSNXLTDLSRNL RQRRFAGVNPLSPLKLKRRHSVEMFFSRRHLCLTSDPSQGSIARSWCTASGFPFFNRRFPFHXPKAWTXYPCXRMMLQLPPGITKDCPVT ECPPKMPLSXHTVSAGLWXXIPSNRELSGSRISMEWTXKSHIWARKGFXMPLKLLWPLVMSSXLKISRKRXIQSWIHYLAGTQLKKESIS GLEIKNVNLTRTFALSFTQNWQILTISRNYKLRQLSSISQSQKMVXKPSCWQRLSVLKGQIWRNLSWYXQSTKMILKLSSSIWKTISFCA FLRQREAFWMTPNWXRDWRQQRPPWQRXSTRXLKPKKMKEKSTRPENVTDQWQQEHLFFILLLMTSKKSTPSTNSLXRLLTCCSTERSSR LTRWKTCRDASLSXWRASPMLSSSTPARRCLRRTSSPSCPRWLFRFCXERKRXTLLNWISCFDSQLNTLIXVPLTSXLLSHGVLSRQLPS WKNFEAXTEMWKDLPSSGGSGXNPSVQKKKNYLKNGRRKVXYRSXFFXEQCALTEXRMLSEILXRKNWVRSMWRGPDWTXLKHSKKAAQP PPYSSSCLRGXMPLKTWRFLAKDLALQLTLENSTMCLXDKVRRRWQKWPWRKLPKEDTGSSSKMFIWXPSGXEPWRSSLKDSAKEATEIT GFSXVLSLHLHQMSISSLKDSWKIPLRSLMNPQQGCWPICMPPCTTLIRIHLKYAPRSRSLKASFFLSATSTPVLLGDXGLAPRAGAEAI LLILETSPFVPVSSTTTXRQTLKSHGKISVISLVRSCMEATSQMTGIANCVGCIXKNSXIHLXLKMNXCWHQVLLPHPTXIMQATTSTXR RCFLQKARHCMASTQMLKXNSXQXHPTLSSELCWRCSPGMHSVVMNWGSLQKKRLRMSWMTFWRNFQKSSTWQRXCKKIQIEAHMFLFAS KNVRGXIFSFGKYVYHLNNWTLVXRGNWHYLLLWKPSSLHXVMTRYQTLGANWLILLLMAXPSGSMTSSCDAENSILGHKTLPFRLSCGS PASSTLSPSXLQSCRRWLEKMSGPWIKRAXLLMLPKKQRKIMDTRQGKVHTSTDSSWRAPAGTPKQEPLLKPVSRSWHALCRSSLQKPPP >In-frame_PMS2_ENST00000406569_chr7_6048628_-_DNAH11_ENST00000409508_chr7_21813384_+_1490aa MERAESSSQCTKTLLAFSWHMFTPLXMKXVPDITRMREDTTIPPQRVFXNKYHCLRTCXRRSKMRYPRKKNAWXTASKSXKPQPLRWEIX KPDLPLKKPSCNXEIMMPKLXSQRSAFRRRKXAGKRPSLMLRSERXQPFRLKCSRNRENVKLTYSRLSLHWWLLQLHSIHSTGSTSVSXK PFPTLPSQLPMLLQPXWSFWLLGEECPKTEVGKQLKSSWERLMIFCKHXLTMTKSTFQRTVXKWXMNTIXKTQSLIQTXFEPNLLQQLAC VPGSSTSLNSMRSTVMWSQNAKHXPKQTXNWLQLLKNXRLSGKSLWIWIEIXADSRLHLKKQQLRKSGVKKRXTKPTKPSNXLTDLSRNL RQRRFAGVNPLSPLKLKRRHSVEMFFSRRHLCLTSDPSQGSIARSWCTASGFPFFNRRFPFHXPKAWTXYPCXRMMLQLPPGITKDCPVT ECPPKMPLSXHTVSAGLWXXIPSNRELSGSRISMEWTXKSHIWARKGFXMPLKLLWPLVMSSXLKISRKRXIQSWIHYLAGTQLKKESIS GLEIKNVNLTRTFALSFTQNWQILTISRNYKLRQLSSISQSQKMVXKPSCWQRLSVLKGQIWRNLSWYXQSTKMILKLSSSIWKTISFCA FLRQREAFWMTPNWXRDWRQQRPPWQRXSTRXLKPKKMKEKSTRPENVTDQWQQEHLFFILLLMTSKKSTPSTNSLXRLLTCCSTERSSR LTRWKTCRDASLSXWRASPMLSSSTPARRCLRRTSSPSCPRWLFRFCXERKRXTLLNWISCFDSQLNTLIXVPLTSXLLSHGVLSRQLPS WKNFEAXTEMWKDLPSSGGSGXNPSVQKKKNYLKNGRRKVXYRSXFFXEQCALTEXRMLSEILXRKNWVRSMWRGPDWTXLKHSKKAAQP PPYSSSCLRGXMPLKTWRFLAKDLALQLTLENSTMCLXDKVRRRWQKWPWRKLPKEDTGSSSKMFIWXPSGXEPWRSSLKDSAKEATEIT GFSXVLSLHLHQMSISSLKDSWKIPLRSLMNPQQGCWPICMPPCTTLIRIHLKYAPRSRSLKASFFLSATSTPVLLGDXGLAPRAGAEAI LLILETSPFVPVSSTTTXRQTLKSHGKISVISLVRSCMEATSQMTGIANCVGCIXKNSXIHLXLKMNXCWHQVLLPHPTXIMQATTSTXR RCFLQKARHCMASTQMLKXNSXQXHPTLSSELCWRCSPGMHSVVMNWGSLQKKRLRMSWMTFWRNFQKSSTWQRXCKKIQIEAHMFLFAS KNVRGXIFSFGKYVYHLNNWTLVXRGNWHYLLLWKPSSLHXVMTRYQTLGANWLILLLMAXPSGSMTSSCDAENSILGHKTLPFRLSCGS PASSTLSPSXLQSCRRWLEKMSGPWIKRAXLLMLPKKQRKIMDTRQGKVHTSTDSSWRAPAGTPKQEPLLKPVSRSWHALCRSSLQKPPP >In-frame_PMS2_ENST00000406569_chr7_6048628_-_DNAH11_ENST00000328843_chr7_21813384_+_1490aa MERAESSSQCTKTLLAFSWHMFTPLXMKXVPDITRMREDTTIPPQRVFXNKYHCLRTCXRRSKMRYPRKKNAWXTASKSXKPQPLRWEIX KPDLPLKKPSCNXEIMMPKLXSQRSAFRRRKXAGKRPSLMLRSERXQPFRLKCSRNRENVKLTYSRLSLHWWLLQLHSIHSTGSTSVSXK PFPTLPSQLPMLLQPXWSFWLLGEECPKTEVGKQLKSSWERLMIFCKHXLTMTKSTFQRTVXKWXMNTIXKTQSLIQTXFEPNLLQQLAC VPGSSTSLNSMRSTVMWSQNAKHXPKQTXNWLQLLKNXRLSGKSLWIWIEIXADSRLHLKKQQLRKSGVKKRXTKPTKPSNXLTDLSRNL RQRRFAGVNPLSPLKLKRRHSVEMFFSRRHLCLTSDPSQGSIARSWCTASGFPFFNRRFPFHXPKAWTXYPCXRMMLQLPPGITKDCPVT ECPPKMPLSXHTVSAGLWXXIPSNRELSGSRISMEWTXKSHIWARKGFXMPLKLLWPLVMSSXLKISRKRXIQSWIHYLAGTQLKKESIS GLEIKNVNLTRTFALSFTQNWQILTISRNYKLRQLSSISQSQKMVXKPSCWQRLSVLKGQIWRNLSWYXQSTKMILKLSSSIWKTISFCA FLRQREAFWMTPNWXRDWRQQRPPWQRXSTRXLKPKKMKEKSTRPENVTDQWQQEHLFFILLLMTSKKSTPSTNSLXRLLTCCSTERSSR LTRWKTCRDASLSXWRASPMLSSSTPARRCLRRTSSPSCPRWLFRFCXERKRXTLLNWISCFDSQLNTLIXVPLTSXLLSHGVLSRQLPS WKNFEAXTEMWKDLPSSGGSGXNPSVQKKKNYLKNGRRKVXYRSXFFXEQCALTEXRMLSEILXRKNWVRSMWRGPDWTXLKHSKKAAQP PPYSSSCLRGXMPLKTWRFLAKDLALQLTLENSTMCLXDKVRRRWQKWPWRKLPKEDTGSSSKMFIWXPSGXEPWRSSLKDSAKEATEIT GFSXVLSLHLHQMSISSLKDSWKIPLRSLMNPQQGCWPICMPPCTTLIRIHLKYAPRSRSLKASFFLSATSTPVLLGDXGLAPRAGAEAI LLILETSPFVPVSSTTTXRQTLKSHGKISVISLVRSCMEATSQMTGIANCVGCIXKNSXIHLXLKMNXCWHQVLLPHPTXIMQATTSTXR RCFLQKARHCMASTQMLKXNSXQXHPTLSSELCWRCSPGMHSVVMNWGSLQKKRLRMSWMTFWRNFQKSSTWQRXCKKIQIEAHMFLFAS KNVRGXIFSFGKYVYHLNNWTLVXRGNWHYLLLWKPSSLHXVMTRYQTLGANWLILLLMAXPSGSMTSSCDAENSILGHKTLPFRLSCGS PASSTLSPSXLQSCRRWLEKMSGPWIKRAXLLMLPKKQRKIMDTRQGKVHTSTDSSWRAPAGTPKQEPLLKPVSRSWHALCRSSLQKPPP |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_PMS2_ENST00000265849_chr7_6048628_-_DNAH11_ENST00000409508_chr7_21813384_+_4472nt ATGGAGCGAGCTGAGAGCTCGAGCCAGTGCACAAAGACTCTATTAGCCTTTTCATGGCACATGTTCACACCACTGTAAATGAAATGAGTA CCAGATATTACCAGAATGAGAGAAGACACAACTATACCACCCCAAAGAGTTTTCTAGAACAAATATCACTGTTTAAGAACCTGTTGAAGA AGAAGCAAAATGAGGTATCCGAGAAAAAAGAACGCCTGGTGAACGGCATCCAAAAGCTAAAAACCACAGCCTCTCAGGTGGGAGATCTAA AAGCCAGACTTGCCTCTCAAGAAGCCGAGCTGCAACTGAGAAATCATGATGCCGAAGCTCTGATCACAAAGATCGGCCTTCAGACGGAGA AAGTGAGCCGGGAAAAGACCATCGCTGATGCTGAGGAGCGAAAGGTGACAGCCATTCAGACTGAAGTGTTCCAGAAACAGAGAGAATGTG AAGCTGACTTACTCAAGGCTGAGCCTGCACTGGTGGCTGCTACAGCTGCACTCAATACACTCAACAGGGTCAACCTCAGTGAGCTGAAAG CCTTTCCCAACCCTCCCATCGCAGTTACCAATGTTACTGCAGCCGTGATGGTCCTTCTGGCTCCTCGGGGAAGAGTGCCCAAAGACCGAA GTTGGAAAGCAGCTAAAGTCTTCATGGGAAAGGTTGATGATTTTTTGCAAGCATTAATTAACTATGACAAAGAGCACATTCCAGAGAACT GTCTAAAAGTGGTGAATGAACACTATTTGAAAGACCCAGAGTTTAATCCAAACCTGATTCGAACCAAATCTTTTGCAGCAGCTGGCCTGT GTGCCTGGGTCATCAACATCATTAAATTCTATGAGGTCTACTGTGATGTGGAGCCAAAACGCCAAGCATTAGCCCAAGCAAACTTAGAAC TGGCTGCAGCTACTGAAAAACTAGAGGCTATCAGGAAAAAGCTTGTGGATCTGGATCGAAATCTGAGCAGACTCACGGCTTCATTTGAAA AAGCAACAGCTGAGAAAGTCCGGTGTCAAGAAGAGGTGAACCAAACCAACAAAACCATCAAATTAGCTAACAGACTTGTCAAGGAACTTG AGGCAAAGAAGATTCGCTGGGGTCAATCCATTAAGTCCTTTGAAGCTCAAGAGAAGACACTCTGTGGAGATGTTCTTCTCACGGCGGCAT TTGTGTCTTACGTCGGACCCTTCACAAGGCAGTATCGCCAGGAGCTGGTGCACTGCAAGTGGGTTCCCTTTCTTCAACAGAAGGTTTCCA TTCCACTAACCGAAGGCCTGGACTTGATATCCATGTTGACGGATGATGCTACAATTGCCGCCTGGAATAACGAAGGACTGCCCAGTGACA GAATGTCCACCGAAAATGCCGCTATCCTAACACACTGTGAGCGCTGGCCTCTGGTGATAGATCCCCAGCAACAGGGAATTAAGTGGATCA AGAATAAGTATGGAATGGACCTGAAAGTCACACATTTGGGCCAGAAAGGGTTTTTGAATGCCATTGAAACTGCTTTGGCCTTTGGTGATG TCATCTTAATTGAAAATCTCGAGGAAACGATAGATCCAGTCCTGGATCCACTACTTGGCAGGAACACAATTAAAAAAGGAAAGTATATCA GGATTGGAGATAAAGAATGTGAATTTAACAAGAACTTTCGCCTTATCCTTCACACAAAATTGGCAAATCCTCACTATAAGCCGGAATTAC AAGCTCAGACAACTCTCCTCAATTTCACAGTCACAGAAGATGGTCTAGAAGCCCAGCTGCTGGCAGAGGTTGTCAGTATTGAAAGGCCAG ATTTGGAGAAACTTAAGTTGGTATTGACAAAGCACCAAAATGATTTTAAAATTGAGCTCAAGTATCTGGAAGACGATCTCCTTTTGCGCC TTTCTGCGGCAGAGGGAAGCTTTCTGGATGACACCAAACTGGTAGAGAGATTGGAGGCAACAAAGACCACCGTGGCAGAGATAGAGCACA AGGTGATTGAAGCCAAAGAAAATGAAAGAAAAATCAACGAGGCCCGAGAATGTTACAGACCAGTGGCAGCAAGAGCATCTCTTCTTTATT TTGTTATTAATGACCTCCAAAAAATCAACCCCCTCTACCAATTCTCTTTGAAGGCTTTTAACGTGCTGTTCCACAGAGCGATCGAGCAGG CTGACAAGGTGGAAGACATGCAGGGACGCATCTCTATCCTGATGGAGAGCATCACCCATGCTGTCTTCCTCTACACCAGCCAGGCGCTGT TTGAGAAGGACAAGCTCACCTTCCTGTCCCAGATGGCTTTTCAGATTTTGTTGAGAAAGAAAGAGATAGACCCTCTTGAATTGGATTTCC TGCTTCGATTCACAGTTGAACACACTCATCTGAGTCCCGTTGACTTCCTAACTTCTCAGTCATGGAGTGCTATCAAGGCAATTGCCGTCA TGGAAGAATTTCGAGGCATAGACCGAGATGTGGAAGGATCTGCCAAGCAGTGGAGGAAGTGGGTAGAATCCGAGTGTCCAGAAAAAGAAA AATTACCTCAAGAATGGAAGAAGAAAAGTTTAATACAGAAGCTGATTCTTCTGAGAGCAATGCGCCCTGACAGAATGACGTATGCTCTCA GAAATTTTGTAGAGGAAAAACTGGGTGCGAAGTATGTGGAGAGGACCAGATTGGACTTAGTTAAAGCATTCGAAGAAAGCAGCCCAGCCA CCCCCATATTCTTCATCCTGTCTCCGGGGGTAGATGCCCTTAAAGACCTGGAGATTCTTGGCAAAAGACTTGGCTTTACAATTGACTCTG GAAAATTCCACAATGTGTCTTTAGGACAAGGTCAGGAGACGGTGGCAGAAGTGGCCCTGGAGAAAGCTTCCAAAGGAGGACACTGGGTCA TCCTCCAAAATGTTCATTTGGTAGCCAAGTGGCTAGGAACCTTGGAGAAGCTCCTTGAAAGATTCAGCCAAGGAAGCCACAGAGATTACA GGGTTTTCATGAGTGCTGAGTCTGCACCTACACCAGATGAGCATATCATCCCTCAAGGACTCCTGGAAAATTCCATTAAGATCACTAATG AACCCCCAACAGGGATGCTGGCCAATTTGCATGCCGCCCTGTACAACTTTGATCAGGATACACTTGAAATATGCTCCAAGGAGCAGGAGT TTAAAAGCATCCTTTTTTCTCTCTGCTACTTCCACGCCTGTGTTGCTGGGAGACTGAGGTTTGGCCCCCAGGGCTGGAGCCGAAGCTATC CTTTTAATCCTGGAGACCTCACCATTTGTGCCAGTGTCCTCTACAACTACTTAGAGGCAAACTCTAAAGTCCCATGGGAAGATCTCCGTT ATCTCTTTGGTGAGATCATGTATGGAGGCCACATCACAGATGACTGGGATCGCAAACTGTGTCGGGTGTATTTAGAAGAATTCATGAATC CATCTCTGACTGAAGATGAACTGATGCTGGCACCAGGTTTTGCTGCCCCACCCTACCTAGATTATGCAGGCTACCACCAGTACATAGAGG AGATGCTTCCTCCAGAAAGCCCGGCACTGTATGGCCTCCACCCAAATGCTGAAATAGAATTCCTGACAGTGACATCCAACACTCTCTTCA GAACTTTGCTGGAGATGCAGCCCAGGAATGCACTCAGTGGTGATGAACTGGGGCAGTCTACAGAAGAAAAGGTTAAGAATGTCTTGGATG ACATTTTGGAGAAACTTCCAGAAGAGTTCAACATGGCAGAGATAATGCAAAAAAATTCAAATAGAAGCCCATATGTTCTTGTTTGCTTCC AAGAATGTGAGAGGATGAATATTCTCATTCGGGAAATACGTATATCACTTGAACAACTGGACCTTAGTTTGAAGGGGGAATTGGCATTAT CTCCTGCTGTGGAAGCCCAGCAGTTTGCATTGAGTTATGACACGGTACCAGACACTTGGAGCAAACTGGCTTATCCTTCTACTTATGGCC TAGCCCAGTGGTTCAATGACCTCCTCCTGCGATGCCGAGAACTCGATACTTGGACACAAGACCTTACCCTTCCGGCTGTCGTGTGGCTCT CCGGCTTCTTCAACCCTCAGTCCTTCTTAACTGCAATCATGCAGACGATGGCTCGAAAAAATGAGTGGCCCCTGGATAAAACGCGCTTGA CTGCTGATGTTACCAAAAAAACAAAGGAAGATTATGGACACCCGCCAAGGGAAGGTGCATACCTCCACGGACTCTTCATGGAGGGCGCCC GCTGGGACACCCAAGCAGGAACCATTGTTGAAGCCCGTCTCAAGGAGCTGGCATGCCCTATGCCGGTCATCTTTGCAAAAGCCACCCCCG TGGACAGACAAGAAACCAAACAGACCTACGAGTGCCCTGTGTATAGAACCAAACTGAGAGGCCCCAGCTACATCTGGACCTTCAGGCTGA >In-frame_PMS2_ENST00000265849_chr7_6048628_-_DNAH11_ENST00000328843_chr7_21813384_+_4472nt ATGGAGCGAGCTGAGAGCTCGAGCCAGTGCACAAAGACTCTATTAGCCTTTTCATGGCACATGTTCACACCACTGTAAATGAAATGAGTA CCAGATATTACCAGAATGAGAGAAGACACAACTATACCACCCCAAAGAGTTTTCTAGAACAAATATCACTGTTTAAGAACCTGTTGAAGA AGAAGCAAAATGAGGTATCCGAGAAAAAAGAACGCCTGGTGAACGGCATCCAAAAGCTAAAAACCACAGCCTCTCAGGTGGGAGATCTAA AAGCCAGACTTGCCTCTCAAGAAGCCGAGCTGCAACTGAGAAATCATGATGCCGAAGCTCTGATCACAAAGATCGGCCTTCAGACGGAGA AAGTGAGCCGGGAAAAGACCATCGCTGATGCTGAGGAGCGAAAGGTGACAGCCATTCAGACTGAAGTGTTCCAGAAACAGAGAGAATGTG AAGCTGACTTACTCAAGGCTGAGCCTGCACTGGTGGCTGCTACAGCTGCACTCAATACACTCAACAGGGTCAACCTCAGTGAGCTGAAAG CCTTTCCCAACCCTCCCATCGCAGTTACCAATGTTACTGCAGCCGTGATGGTCCTTCTGGCTCCTCGGGGAAGAGTGCCCAAAGACCGAA GTTGGAAAGCAGCTAAAGTCTTCATGGGAAAGGTTGATGATTTTTTGCAAGCATTAATTAACTATGACAAAGAGCACATTCCAGAGAACT GTCTAAAAGTGGTGAATGAACACTATTTGAAAGACCCAGAGTTTAATCCAAACCTGATTCGAACCAAATCTTTTGCAGCAGCTGGCCTGT GTGCCTGGGTCATCAACATCATTAAATTCTATGAGGTCTACTGTGATGTGGAGCCAAAACGCCAAGCATTAGCCCAAGCAAACTTAGAAC TGGCTGCAGCTACTGAAAAACTAGAGGCTATCAGGAAAAAGCTTGTGGATCTGGATCGAAATCTGAGCAGACTCACGGCTTCATTTGAAA AAGCAACAGCTGAGAAAGTCCGGTGTCAAGAAGAGGTGAACCAAACCAACAAAACCATCAAATTAGCTAACAGACTTGTCAAGGAACTTG AGGCAAAGAAGATTCGCTGGGGTCAATCCATTAAGTCCTTTGAAGCTCAAGAGAAGACACTCTGTGGAGATGTTCTTCTCACGGCGGCAT TTGTGTCTTACGTCGGACCCTTCACAAGGCAGTATCGCCAGGAGCTGGTGCACTGCAAGTGGGTTCCCTTTCTTCAACAGAAGGTTTCCA TTCCACTAACCGAAGGCCTGGACTTGATATCCATGTTGACGGATGATGCTACAATTGCCGCCTGGAATAACGAAGGACTGCCCAGTGACA GAATGTCCACCGAAAATGCCGCTATCCTAACACACTGTGAGCGCTGGCCTCTGGTGATAGATCCCCAGCAACAGGGAATTAAGTGGATCA AGAATAAGTATGGAATGGACCTGAAAGTCACACATTTGGGCCAGAAAGGGTTTTTGAATGCCATTGAAACTGCTTTGGCCTTTGGTGATG TCATCTTAATTGAAAATCTCGAGGAAACGATAGATCCAGTCCTGGATCCACTACTTGGCAGGAACACAATTAAAAAAGGAAAGTATATCA GGATTGGAGATAAAGAATGTGAATTTAACAAGAACTTTCGCCTTATCCTTCACACAAAATTGGCAAATCCTCACTATAAGCCGGAATTAC AAGCTCAGACAACTCTCCTCAATTTCACAGTCACAGAAGATGGTCTAGAAGCCCAGCTGCTGGCAGAGGTTGTCAGTATTGAAAGGCCAG ATTTGGAGAAACTTAAGTTGGTATTGACAAAGCACCAAAATGATTTTAAAATTGAGCTCAAGTATCTGGAAGACGATCTCCTTTTGCGCC TTTCTGCGGCAGAGGGAAGCTTTCTGGATGACACCAAACTGGTAGAGAGATTGGAGGCAACAAAGACCACCGTGGCAGAGATAGAGCACA AGGTGATTGAAGCCAAAGAAAATGAAAGAAAAATCAACGAGGCCCGAGAATGTTACAGACCAGTGGCAGCAAGAGCATCTCTTCTTTATT TTGTTATTAATGACCTCCAAAAAATCAACCCCCTCTACCAATTCTCTTTGAAGGCTTTTAACGTGCTGTTCCACAGAGCGATCGAGCAGG CTGACAAGGTGGAAGACATGCAGGGACGCATCTCTATCCTGATGGAGAGCATCACCCATGCTGTCTTCCTCTACACCAGCCAGGCGCTGT TTGAGAAGGACAAGCTCACCTTCCTGTCCCAGATGGCTTTTCAGATTTTGTTGAGAAAGAAAGAGATAGACCCTCTTGAATTGGATTTCC TGCTTCGATTCACAGTTGAACACACTCATCTGAGTCCCGTTGACTTCCTAACTTCTCAGTCATGGAGTGCTATCAAGGCAATTGCCGTCA TGGAAGAATTTCGAGGCATAGACCGAGATGTGGAAGGATCTGCCAAGCAGTGGAGGAAGTGGGTAGAATCCGAGTGTCCAGAAAAAGAAA AATTACCTCAAGAATGGAAGAAGAAAAGTTTAATACAGAAGCTGATTCTTCTGAGAGCAATGCGCCCTGACAGAATGACGTATGCTCTCA GAAATTTTGTAGAGGAAAAACTGGGTGCGAAGTATGTGGAGAGGACCAGATTGGACTTAGTTAAAGCATTCGAAGAAAGCAGCCCAGCCA CCCCCATATTCTTCATCCTGTCTCCGGGGGTAGATGCCCTTAAAGACCTGGAGATTCTTGGCAAAAGACTTGGCTTTACAATTGACTCTG GAAAATTCCACAATGTGTCTTTAGGACAAGGTCAGGAGACGGTGGCAGAAGTGGCCCTGGAGAAAGCTTCCAAAGGAGGACACTGGGTCA TCCTCCAAAATGTTCATTTGGTAGCCAAGTGGCTAGGAACCTTGGAGAAGCTCCTTGAAAGATTCAGCCAAGGAAGCCACAGAGATTACA GGGTTTTCATGAGTGCTGAGTCTGCACCTACACCAGATGAGCATATCATCCCTCAAGGACTCCTGGAAAATTCCATTAAGATCACTAATG AACCCCCAACAGGGATGCTGGCCAATTTGCATGCCGCCCTGTACAACTTTGATCAGGATACACTTGAAATATGCTCCAAGGAGCAGGAGT TTAAAAGCATCCTTTTTTCTCTCTGCTACTTCCACGCCTGTGTTGCTGGGAGACTGAGGTTTGGCCCCCAGGGCTGGAGCCGAAGCTATC CTTTTAATCCTGGAGACCTCACCATTTGTGCCAGTGTCCTCTACAACTACTTAGAGGCAAACTCTAAAGTCCCATGGGAAGATCTCCGTT ATCTCTTTGGTGAGATCATGTATGGAGGCCACATCACAGATGACTGGGATCGCAAACTGTGTCGGGTGTATTTAGAAGAATTCATGAATC CATCTCTGACTGAAGATGAACTGATGCTGGCACCAGGTTTTGCTGCCCCACCCTACCTAGATTATGCAGGCTACCACCAGTACATAGAGG AGATGCTTCCTCCAGAAAGCCCGGCACTGTATGGCCTCCACCCAAATGCTGAAATAGAATTCCTGACAGTGACATCCAACACTCTCTTCA GAACTTTGCTGGAGATGCAGCCCAGGAATGCACTCAGTGGTGATGAACTGGGGCAGTCTACAGAAGAAAAGGTTAAGAATGTCTTGGATG ACATTTTGGAGAAACTTCCAGAAGAGTTCAACATGGCAGAGATAATGCAAAAAAATTCAAATAGAAGCCCATATGTTCTTGTTTGCTTCC AAGAATGTGAGAGGATGAATATTCTCATTCGGGAAATACGTATATCACTTGAACAACTGGACCTTAGTTTGAAGGGGGAATTGGCATTAT CTCCTGCTGTGGAAGCCCAGCAGTTTGCATTGAGTTATGACACGGTACCAGACACTTGGAGCAAACTGGCTTATCCTTCTACTTATGGCC TAGCCCAGTGGTTCAATGACCTCCTCCTGCGATGCCGAGAACTCGATACTTGGACACAAGACCTTACCCTTCCGGCTGTCGTGTGGCTCT CCGGCTTCTTCAACCCTCAGTCCTTCTTAACTGCAATCATGCAGACGATGGCTCGAAAAAATGAGTGGCCCCTGGATAAAACGCGCTTGA CTGCTGATGTTACCAAAAAAACAAAGGAAGATTATGGACACCCGCCAAGGGAAGGTGCATACCTCCACGGACTCTTCATGGAGGGCGCCC GCTGGGACACCCAAGCAGGAACCATTGTTGAAGCCCGTCTCAAGGAGCTGGCATGCCCTATGCCGGTCATCTTTGCAAAAGCCACCCCCG TGGACAGACAAGAAACCAAACAGACCTACGAGTGCCCTGTGTATAGAACCAAACTGAGAGGCCCCAGCTACATCTGGACCTTCAGGCTGA >In-frame_PMS2_ENST00000382321_chr7_6048628_-_DNAH11_ENST00000409508_chr7_21813384_+_4472nt ATGGAGCGAGCTGAGAGCTCGAGCCAGTGCACAAAGACTCTATTAGCCTTTTCATGGCACATGTTCACACCACTGTAAATGAAATGAGTA CCAGATATTACCAGAATGAGAGAAGACACAACTATACCACCCCAAAGAGTTTTCTAGAACAAATATCACTGTTTAAGAACCTGTTGAAGA AGAAGCAAAATGAGGTATCCGAGAAAAAAGAACGCCTGGTGAACGGCATCCAAAAGCTAAAAACCACAGCCTCTCAGGTGGGAGATCTAA AAGCCAGACTTGCCTCTCAAGAAGCCGAGCTGCAACTGAGAAATCATGATGCCGAAGCTCTGATCACAAAGATCGGCCTTCAGACGGAGA AAGTGAGCCGGGAAAAGACCATCGCTGATGCTGAGGAGCGAAAGGTGACAGCCATTCAGACTGAAGTGTTCCAGAAACAGAGAGAATGTG AAGCTGACTTACTCAAGGCTGAGCCTGCACTGGTGGCTGCTACAGCTGCACTCAATACACTCAACAGGGTCAACCTCAGTGAGCTGAAAG CCTTTCCCAACCCTCCCATCGCAGTTACCAATGTTACTGCAGCCGTGATGGTCCTTCTGGCTCCTCGGGGAAGAGTGCCCAAAGACCGAA GTTGGAAAGCAGCTAAAGTCTTCATGGGAAAGGTTGATGATTTTTTGCAAGCATTAATTAACTATGACAAAGAGCACATTCCAGAGAACT GTCTAAAAGTGGTGAATGAACACTATTTGAAAGACCCAGAGTTTAATCCAAACCTGATTCGAACCAAATCTTTTGCAGCAGCTGGCCTGT GTGCCTGGGTCATCAACATCATTAAATTCTATGAGGTCTACTGTGATGTGGAGCCAAAACGCCAAGCATTAGCCCAAGCAAACTTAGAAC TGGCTGCAGCTACTGAAAAACTAGAGGCTATCAGGAAAAAGCTTGTGGATCTGGATCGAAATCTGAGCAGACTCACGGCTTCATTTGAAA AAGCAACAGCTGAGAAAGTCCGGTGTCAAGAAGAGGTGAACCAAACCAACAAAACCATCAAATTAGCTAACAGACTTGTCAAGGAACTTG AGGCAAAGAAGATTCGCTGGGGTCAATCCATTAAGTCCTTTGAAGCTCAAGAGAAGACACTCTGTGGAGATGTTCTTCTCACGGCGGCAT TTGTGTCTTACGTCGGACCCTTCACAAGGCAGTATCGCCAGGAGCTGGTGCACTGCAAGTGGGTTCCCTTTCTTCAACAGAAGGTTTCCA TTCCACTAACCGAAGGCCTGGACTTGATATCCATGTTGACGGATGATGCTACAATTGCCGCCTGGAATAACGAAGGACTGCCCAGTGACA GAATGTCCACCGAAAATGCCGCTATCCTAACACACTGTGAGCGCTGGCCTCTGGTGATAGATCCCCAGCAACAGGGAATTAAGTGGATCA AGAATAAGTATGGAATGGACCTGAAAGTCACACATTTGGGCCAGAAAGGGTTTTTGAATGCCATTGAAACTGCTTTGGCCTTTGGTGATG TCATCTTAATTGAAAATCTCGAGGAAACGATAGATCCAGTCCTGGATCCACTACTTGGCAGGAACACAATTAAAAAAGGAAAGTATATCA GGATTGGAGATAAAGAATGTGAATTTAACAAGAACTTTCGCCTTATCCTTCACACAAAATTGGCAAATCCTCACTATAAGCCGGAATTAC AAGCTCAGACAACTCTCCTCAATTTCACAGTCACAGAAGATGGTCTAGAAGCCCAGCTGCTGGCAGAGGTTGTCAGTATTGAAAGGCCAG ATTTGGAGAAACTTAAGTTGGTATTGACAAAGCACCAAAATGATTTTAAAATTGAGCTCAAGTATCTGGAAGACGATCTCCTTTTGCGCC TTTCTGCGGCAGAGGGAAGCTTTCTGGATGACACCAAACTGGTAGAGAGATTGGAGGCAACAAAGACCACCGTGGCAGAGATAGAGCACA AGGTGATTGAAGCCAAAGAAAATGAAAGAAAAATCAACGAGGCCCGAGAATGTTACAGACCAGTGGCAGCAAGAGCATCTCTTCTTTATT TTGTTATTAATGACCTCCAAAAAATCAACCCCCTCTACCAATTCTCTTTGAAGGCTTTTAACGTGCTGTTCCACAGAGCGATCGAGCAGG CTGACAAGGTGGAAGACATGCAGGGACGCATCTCTATCCTGATGGAGAGCATCACCCATGCTGTCTTCCTCTACACCAGCCAGGCGCTGT TTGAGAAGGACAAGCTCACCTTCCTGTCCCAGATGGCTTTTCAGATTTTGTTGAGAAAGAAAGAGATAGACCCTCTTGAATTGGATTTCC TGCTTCGATTCACAGTTGAACACACTCATCTGAGTCCCGTTGACTTCCTAACTTCTCAGTCATGGAGTGCTATCAAGGCAATTGCCGTCA TGGAAGAATTTCGAGGCATAGACCGAGATGTGGAAGGATCTGCCAAGCAGTGGAGGAAGTGGGTAGAATCCGAGTGTCCAGAAAAAGAAA AATTACCTCAAGAATGGAAGAAGAAAAGTTTAATACAGAAGCTGATTCTTCTGAGAGCAATGCGCCCTGACAGAATGACGTATGCTCTCA GAAATTTTGTAGAGGAAAAACTGGGTGCGAAGTATGTGGAGAGGACCAGATTGGACTTAGTTAAAGCATTCGAAGAAAGCAGCCCAGCCA CCCCCATATTCTTCATCCTGTCTCCGGGGGTAGATGCCCTTAAAGACCTGGAGATTCTTGGCAAAAGACTTGGCTTTACAATTGACTCTG GAAAATTCCACAATGTGTCTTTAGGACAAGGTCAGGAGACGGTGGCAGAAGTGGCCCTGGAGAAAGCTTCCAAAGGAGGACACTGGGTCA TCCTCCAAAATGTTCATTTGGTAGCCAAGTGGCTAGGAACCTTGGAGAAGCTCCTTGAAAGATTCAGCCAAGGAAGCCACAGAGATTACA GGGTTTTCATGAGTGCTGAGTCTGCACCTACACCAGATGAGCATATCATCCCTCAAGGACTCCTGGAAAATTCCATTAAGATCACTAATG AACCCCCAACAGGGATGCTGGCCAATTTGCATGCCGCCCTGTACAACTTTGATCAGGATACACTTGAAATATGCTCCAAGGAGCAGGAGT TTAAAAGCATCCTTTTTTCTCTCTGCTACTTCCACGCCTGTGTTGCTGGGAGACTGAGGTTTGGCCCCCAGGGCTGGAGCCGAAGCTATC CTTTTAATCCTGGAGACCTCACCATTTGTGCCAGTGTCCTCTACAACTACTTAGAGGCAAACTCTAAAGTCCCATGGGAAGATCTCCGTT ATCTCTTTGGTGAGATCATGTATGGAGGCCACATCACAGATGACTGGGATCGCAAACTGTGTCGGGTGTATTTAGAAGAATTCATGAATC CATCTCTGACTGAAGATGAACTGATGCTGGCACCAGGTTTTGCTGCCCCACCCTACCTAGATTATGCAGGCTACCACCAGTACATAGAGG AGATGCTTCCTCCAGAAAGCCCGGCACTGTATGGCCTCCACCCAAATGCTGAAATAGAATTCCTGACAGTGACATCCAACACTCTCTTCA GAACTTTGCTGGAGATGCAGCCCAGGAATGCACTCAGTGGTGATGAACTGGGGCAGTCTACAGAAGAAAAGGTTAAGAATGTCTTGGATG ACATTTTGGAGAAACTTCCAGAAGAGTTCAACATGGCAGAGATAATGCAAAAAAATTCAAATAGAAGCCCATATGTTCTTGTTTGCTTCC AAGAATGTGAGAGGATGAATATTCTCATTCGGGAAATACGTATATCACTTGAACAACTGGACCTTAGTTTGAAGGGGGAATTGGCATTAT CTCCTGCTGTGGAAGCCCAGCAGTTTGCATTGAGTTATGACACGGTACCAGACACTTGGAGCAAACTGGCTTATCCTTCTACTTATGGCC TAGCCCAGTGGTTCAATGACCTCCTCCTGCGATGCCGAGAACTCGATACTTGGACACAAGACCTTACCCTTCCGGCTGTCGTGTGGCTCT CCGGCTTCTTCAACCCTCAGTCCTTCTTAACTGCAATCATGCAGACGATGGCTCGAAAAAATGAGTGGCCCCTGGATAAAACGCGCTTGA CTGCTGATGTTACCAAAAAAACAAAGGAAGATTATGGACACCCGCCAAGGGAAGGTGCATACCTCCACGGACTCTTCATGGAGGGCGCCC GCTGGGACACCCAAGCAGGAACCATTGTTGAAGCCCGTCTCAAGGAGCTGGCATGCCCTATGCCGGTCATCTTTGCAAAAGCCACCCCCG TGGACAGACAAGAAACCAAACAGACCTACGAGTGCCCTGTGTATAGAACCAAACTGAGAGGCCCCAGCTACATCTGGACCTTCAGGCTGA >In-frame_PMS2_ENST00000382321_chr7_6048628_-_DNAH11_ENST00000328843_chr7_21813384_+_4472nt ATGGAGCGAGCTGAGAGCTCGAGCCAGTGCACAAAGACTCTATTAGCCTTTTCATGGCACATGTTCACACCACTGTAAATGAAATGAGTA CCAGATATTACCAGAATGAGAGAAGACACAACTATACCACCCCAAAGAGTTTTCTAGAACAAATATCACTGTTTAAGAACCTGTTGAAGA AGAAGCAAAATGAGGTATCCGAGAAAAAAGAACGCCTGGTGAACGGCATCCAAAAGCTAAAAACCACAGCCTCTCAGGTGGGAGATCTAA AAGCCAGACTTGCCTCTCAAGAAGCCGAGCTGCAACTGAGAAATCATGATGCCGAAGCTCTGATCACAAAGATCGGCCTTCAGACGGAGA AAGTGAGCCGGGAAAAGACCATCGCTGATGCTGAGGAGCGAAAGGTGACAGCCATTCAGACTGAAGTGTTCCAGAAACAGAGAGAATGTG AAGCTGACTTACTCAAGGCTGAGCCTGCACTGGTGGCTGCTACAGCTGCACTCAATACACTCAACAGGGTCAACCTCAGTGAGCTGAAAG CCTTTCCCAACCCTCCCATCGCAGTTACCAATGTTACTGCAGCCGTGATGGTCCTTCTGGCTCCTCGGGGAAGAGTGCCCAAAGACCGAA GTTGGAAAGCAGCTAAAGTCTTCATGGGAAAGGTTGATGATTTTTTGCAAGCATTAATTAACTATGACAAAGAGCACATTCCAGAGAACT GTCTAAAAGTGGTGAATGAACACTATTTGAAAGACCCAGAGTTTAATCCAAACCTGATTCGAACCAAATCTTTTGCAGCAGCTGGCCTGT GTGCCTGGGTCATCAACATCATTAAATTCTATGAGGTCTACTGTGATGTGGAGCCAAAACGCCAAGCATTAGCCCAAGCAAACTTAGAAC TGGCTGCAGCTACTGAAAAACTAGAGGCTATCAGGAAAAAGCTTGTGGATCTGGATCGAAATCTGAGCAGACTCACGGCTTCATTTGAAA AAGCAACAGCTGAGAAAGTCCGGTGTCAAGAAGAGGTGAACCAAACCAACAAAACCATCAAATTAGCTAACAGACTTGTCAAGGAACTTG AGGCAAAGAAGATTCGCTGGGGTCAATCCATTAAGTCCTTTGAAGCTCAAGAGAAGACACTCTGTGGAGATGTTCTTCTCACGGCGGCAT TTGTGTCTTACGTCGGACCCTTCACAAGGCAGTATCGCCAGGAGCTGGTGCACTGCAAGTGGGTTCCCTTTCTTCAACAGAAGGTTTCCA TTCCACTAACCGAAGGCCTGGACTTGATATCCATGTTGACGGATGATGCTACAATTGCCGCCTGGAATAACGAAGGACTGCCCAGTGACA GAATGTCCACCGAAAATGCCGCTATCCTAACACACTGTGAGCGCTGGCCTCTGGTGATAGATCCCCAGCAACAGGGAATTAAGTGGATCA AGAATAAGTATGGAATGGACCTGAAAGTCACACATTTGGGCCAGAAAGGGTTTTTGAATGCCATTGAAACTGCTTTGGCCTTTGGTGATG TCATCTTAATTGAAAATCTCGAGGAAACGATAGATCCAGTCCTGGATCCACTACTTGGCAGGAACACAATTAAAAAAGGAAAGTATATCA GGATTGGAGATAAAGAATGTGAATTTAACAAGAACTTTCGCCTTATCCTTCACACAAAATTGGCAAATCCTCACTATAAGCCGGAATTAC AAGCTCAGACAACTCTCCTCAATTTCACAGTCACAGAAGATGGTCTAGAAGCCCAGCTGCTGGCAGAGGTTGTCAGTATTGAAAGGCCAG ATTTGGAGAAACTTAAGTTGGTATTGACAAAGCACCAAAATGATTTTAAAATTGAGCTCAAGTATCTGGAAGACGATCTCCTTTTGCGCC TTTCTGCGGCAGAGGGAAGCTTTCTGGATGACACCAAACTGGTAGAGAGATTGGAGGCAACAAAGACCACCGTGGCAGAGATAGAGCACA AGGTGATTGAAGCCAAAGAAAATGAAAGAAAAATCAACGAGGCCCGAGAATGTTACAGACCAGTGGCAGCAAGAGCATCTCTTCTTTATT TTGTTATTAATGACCTCCAAAAAATCAACCCCCTCTACCAATTCTCTTTGAAGGCTTTTAACGTGCTGTTCCACAGAGCGATCGAGCAGG CTGACAAGGTGGAAGACATGCAGGGACGCATCTCTATCCTGATGGAGAGCATCACCCATGCTGTCTTCCTCTACACCAGCCAGGCGCTGT TTGAGAAGGACAAGCTCACCTTCCTGTCCCAGATGGCTTTTCAGATTTTGTTGAGAAAGAAAGAGATAGACCCTCTTGAATTGGATTTCC TGCTTCGATTCACAGTTGAACACACTCATCTGAGTCCCGTTGACTTCCTAACTTCTCAGTCATGGAGTGCTATCAAGGCAATTGCCGTCA TGGAAGAATTTCGAGGCATAGACCGAGATGTGGAAGGATCTGCCAAGCAGTGGAGGAAGTGGGTAGAATCCGAGTGTCCAGAAAAAGAAA AATTACCTCAAGAATGGAAGAAGAAAAGTTTAATACAGAAGCTGATTCTTCTGAGAGCAATGCGCCCTGACAGAATGACGTATGCTCTCA GAAATTTTGTAGAGGAAAAACTGGGTGCGAAGTATGTGGAGAGGACCAGATTGGACTTAGTTAAAGCATTCGAAGAAAGCAGCCCAGCCA CCCCCATATTCTTCATCCTGTCTCCGGGGGTAGATGCCCTTAAAGACCTGGAGATTCTTGGCAAAAGACTTGGCTTTACAATTGACTCTG GAAAATTCCACAATGTGTCTTTAGGACAAGGTCAGGAGACGGTGGCAGAAGTGGCCCTGGAGAAAGCTTCCAAAGGAGGACACTGGGTCA TCCTCCAAAATGTTCATTTGGTAGCCAAGTGGCTAGGAACCTTGGAGAAGCTCCTTGAAAGATTCAGCCAAGGAAGCCACAGAGATTACA GGGTTTTCATGAGTGCTGAGTCTGCACCTACACCAGATGAGCATATCATCCCTCAAGGACTCCTGGAAAATTCCATTAAGATCACTAATG AACCCCCAACAGGGATGCTGGCCAATTTGCATGCCGCCCTGTACAACTTTGATCAGGATACACTTGAAATATGCTCCAAGGAGCAGGAGT TTAAAAGCATCCTTTTTTCTCTCTGCTACTTCCACGCCTGTGTTGCTGGGAGACTGAGGTTTGGCCCCCAGGGCTGGAGCCGAAGCTATC CTTTTAATCCTGGAGACCTCACCATTTGTGCCAGTGTCCTCTACAACTACTTAGAGGCAAACTCTAAAGTCCCATGGGAAGATCTCCGTT ATCTCTTTGGTGAGATCATGTATGGAGGCCACATCACAGATGACTGGGATCGCAAACTGTGTCGGGTGTATTTAGAAGAATTCATGAATC CATCTCTGACTGAAGATGAACTGATGCTGGCACCAGGTTTTGCTGCCCCACCCTACCTAGATTATGCAGGCTACCACCAGTACATAGAGG AGATGCTTCCTCCAGAAAGCCCGGCACTGTATGGCCTCCACCCAAATGCTGAAATAGAATTCCTGACAGTGACATCCAACACTCTCTTCA GAACTTTGCTGGAGATGCAGCCCAGGAATGCACTCAGTGGTGATGAACTGGGGCAGTCTACAGAAGAAAAGGTTAAGAATGTCTTGGATG ACATTTTGGAGAAACTTCCAGAAGAGTTCAACATGGCAGAGATAATGCAAAAAAATTCAAATAGAAGCCCATATGTTCTTGTTTGCTTCC AAGAATGTGAGAGGATGAATATTCTCATTCGGGAAATACGTATATCACTTGAACAACTGGACCTTAGTTTGAAGGGGGAATTGGCATTAT CTCCTGCTGTGGAAGCCCAGCAGTTTGCATTGAGTTATGACACGGTACCAGACACTTGGAGCAAACTGGCTTATCCTTCTACTTATGGCC TAGCCCAGTGGTTCAATGACCTCCTCCTGCGATGCCGAGAACTCGATACTTGGACACAAGACCTTACCCTTCCGGCTGTCGTGTGGCTCT CCGGCTTCTTCAACCCTCAGTCCTTCTTAACTGCAATCATGCAGACGATGGCTCGAAAAAATGAGTGGCCCCTGGATAAAACGCGCTTGA CTGCTGATGTTACCAAAAAAACAAAGGAAGATTATGGACACCCGCCAAGGGAAGGTGCATACCTCCACGGACTCTTCATGGAGGGCGCCC GCTGGGACACCCAAGCAGGAACCATTGTTGAAGCCCGTCTCAAGGAGCTGGCATGCCCTATGCCGGTCATCTTTGCAAAAGCCACCCCCG TGGACAGACAAGAAACCAAACAGACCTACGAGTGCCCTGTGTATAGAACCAAACTGAGAGGCCCCAGCTACATCTGGACCTTCAGGCTGA >In-frame_PMS2_ENST00000406569_chr7_6048628_-_DNAH11_ENST00000409508_chr7_21813384_+_4472nt ATGGAGCGAGCTGAGAGCTCGAGCCAGTGCACAAAGACTCTATTAGCCTTTTCATGGCACATGTTCACACCACTGTAAATGAAATGAGTA CCAGATATTACCAGAATGAGAGAAGACACAACTATACCACCCCAAAGAGTTTTCTAGAACAAATATCACTGTTTAAGAACCTGTTGAAGA AGAAGCAAAATGAGGTATCCGAGAAAAAAGAACGCCTGGTGAACGGCATCCAAAAGCTAAAAACCACAGCCTCTCAGGTGGGAGATCTAA AAGCCAGACTTGCCTCTCAAGAAGCCGAGCTGCAACTGAGAAATCATGATGCCGAAGCTCTGATCACAAAGATCGGCCTTCAGACGGAGA AAGTGAGCCGGGAAAAGACCATCGCTGATGCTGAGGAGCGAAAGGTGACAGCCATTCAGACTGAAGTGTTCCAGAAACAGAGAGAATGTG AAGCTGACTTACTCAAGGCTGAGCCTGCACTGGTGGCTGCTACAGCTGCACTCAATACACTCAACAGGGTCAACCTCAGTGAGCTGAAAG CCTTTCCCAACCCTCCCATCGCAGTTACCAATGTTACTGCAGCCGTGATGGTCCTTCTGGCTCCTCGGGGAAGAGTGCCCAAAGACCGAA GTTGGAAAGCAGCTAAAGTCTTCATGGGAAAGGTTGATGATTTTTTGCAAGCATTAATTAACTATGACAAAGAGCACATTCCAGAGAACT GTCTAAAAGTGGTGAATGAACACTATTTGAAAGACCCAGAGTTTAATCCAAACCTGATTCGAACCAAATCTTTTGCAGCAGCTGGCCTGT GTGCCTGGGTCATCAACATCATTAAATTCTATGAGGTCTACTGTGATGTGGAGCCAAAACGCCAAGCATTAGCCCAAGCAAACTTAGAAC TGGCTGCAGCTACTGAAAAACTAGAGGCTATCAGGAAAAAGCTTGTGGATCTGGATCGAAATCTGAGCAGACTCACGGCTTCATTTGAAA AAGCAACAGCTGAGAAAGTCCGGTGTCAAGAAGAGGTGAACCAAACCAACAAAACCATCAAATTAGCTAACAGACTTGTCAAGGAACTTG AGGCAAAGAAGATTCGCTGGGGTCAATCCATTAAGTCCTTTGAAGCTCAAGAGAAGACACTCTGTGGAGATGTTCTTCTCACGGCGGCAT TTGTGTCTTACGTCGGACCCTTCACAAGGCAGTATCGCCAGGAGCTGGTGCACTGCAAGTGGGTTCCCTTTCTTCAACAGAAGGTTTCCA TTCCACTAACCGAAGGCCTGGACTTGATATCCATGTTGACGGATGATGCTACAATTGCCGCCTGGAATAACGAAGGACTGCCCAGTGACA GAATGTCCACCGAAAATGCCGCTATCCTAACACACTGTGAGCGCTGGCCTCTGGTGATAGATCCCCAGCAACAGGGAATTAAGTGGATCA AGAATAAGTATGGAATGGACCTGAAAGTCACACATTTGGGCCAGAAAGGGTTTTTGAATGCCATTGAAACTGCTTTGGCCTTTGGTGATG TCATCTTAATTGAAAATCTCGAGGAAACGATAGATCCAGTCCTGGATCCACTACTTGGCAGGAACACAATTAAAAAAGGAAAGTATATCA GGATTGGAGATAAAGAATGTGAATTTAACAAGAACTTTCGCCTTATCCTTCACACAAAATTGGCAAATCCTCACTATAAGCCGGAATTAC AAGCTCAGACAACTCTCCTCAATTTCACAGTCACAGAAGATGGTCTAGAAGCCCAGCTGCTGGCAGAGGTTGTCAGTATTGAAAGGCCAG ATTTGGAGAAACTTAAGTTGGTATTGACAAAGCACCAAAATGATTTTAAAATTGAGCTCAAGTATCTGGAAGACGATCTCCTTTTGCGCC TTTCTGCGGCAGAGGGAAGCTTTCTGGATGACACCAAACTGGTAGAGAGATTGGAGGCAACAAAGACCACCGTGGCAGAGATAGAGCACA AGGTGATTGAAGCCAAAGAAAATGAAAGAAAAATCAACGAGGCCCGAGAATGTTACAGACCAGTGGCAGCAAGAGCATCTCTTCTTTATT TTGTTATTAATGACCTCCAAAAAATCAACCCCCTCTACCAATTCTCTTTGAAGGCTTTTAACGTGCTGTTCCACAGAGCGATCGAGCAGG CTGACAAGGTGGAAGACATGCAGGGACGCATCTCTATCCTGATGGAGAGCATCACCCATGCTGTCTTCCTCTACACCAGCCAGGCGCTGT TTGAGAAGGACAAGCTCACCTTCCTGTCCCAGATGGCTTTTCAGATTTTGTTGAGAAAGAAAGAGATAGACCCTCTTGAATTGGATTTCC TGCTTCGATTCACAGTTGAACACACTCATCTGAGTCCCGTTGACTTCCTAACTTCTCAGTCATGGAGTGCTATCAAGGCAATTGCCGTCA TGGAAGAATTTCGAGGCATAGACCGAGATGTGGAAGGATCTGCCAAGCAGTGGAGGAAGTGGGTAGAATCCGAGTGTCCAGAAAAAGAAA AATTACCTCAAGAATGGAAGAAGAAAAGTTTAATACAGAAGCTGATTCTTCTGAGAGCAATGCGCCCTGACAGAATGACGTATGCTCTCA GAAATTTTGTAGAGGAAAAACTGGGTGCGAAGTATGTGGAGAGGACCAGATTGGACTTAGTTAAAGCATTCGAAGAAAGCAGCCCAGCCA CCCCCATATTCTTCATCCTGTCTCCGGGGGTAGATGCCCTTAAAGACCTGGAGATTCTTGGCAAAAGACTTGGCTTTACAATTGACTCTG GAAAATTCCACAATGTGTCTTTAGGACAAGGTCAGGAGACGGTGGCAGAAGTGGCCCTGGAGAAAGCTTCCAAAGGAGGACACTGGGTCA TCCTCCAAAATGTTCATTTGGTAGCCAAGTGGCTAGGAACCTTGGAGAAGCTCCTTGAAAGATTCAGCCAAGGAAGCCACAGAGATTACA GGGTTTTCATGAGTGCTGAGTCTGCACCTACACCAGATGAGCATATCATCCCTCAAGGACTCCTGGAAAATTCCATTAAGATCACTAATG AACCCCCAACAGGGATGCTGGCCAATTTGCATGCCGCCCTGTACAACTTTGATCAGGATACACTTGAAATATGCTCCAAGGAGCAGGAGT TTAAAAGCATCCTTTTTTCTCTCTGCTACTTCCACGCCTGTGTTGCTGGGAGACTGAGGTTTGGCCCCCAGGGCTGGAGCCGAAGCTATC CTTTTAATCCTGGAGACCTCACCATTTGTGCCAGTGTCCTCTACAACTACTTAGAGGCAAACTCTAAAGTCCCATGGGAAGATCTCCGTT ATCTCTTTGGTGAGATCATGTATGGAGGCCACATCACAGATGACTGGGATCGCAAACTGTGTCGGGTGTATTTAGAAGAATTCATGAATC CATCTCTGACTGAAGATGAACTGATGCTGGCACCAGGTTTTGCTGCCCCACCCTACCTAGATTATGCAGGCTACCACCAGTACATAGAGG AGATGCTTCCTCCAGAAAGCCCGGCACTGTATGGCCTCCACCCAAATGCTGAAATAGAATTCCTGACAGTGACATCCAACACTCTCTTCA GAACTTTGCTGGAGATGCAGCCCAGGAATGCACTCAGTGGTGATGAACTGGGGCAGTCTACAGAAGAAAAGGTTAAGAATGTCTTGGATG ACATTTTGGAGAAACTTCCAGAAGAGTTCAACATGGCAGAGATAATGCAAAAAAATTCAAATAGAAGCCCATATGTTCTTGTTTGCTTCC AAGAATGTGAGAGGATGAATATTCTCATTCGGGAAATACGTATATCACTTGAACAACTGGACCTTAGTTTGAAGGGGGAATTGGCATTAT CTCCTGCTGTGGAAGCCCAGCAGTTTGCATTGAGTTATGACACGGTACCAGACACTTGGAGCAAACTGGCTTATCCTTCTACTTATGGCC TAGCCCAGTGGTTCAATGACCTCCTCCTGCGATGCCGAGAACTCGATACTTGGACACAAGACCTTACCCTTCCGGCTGTCGTGTGGCTCT CCGGCTTCTTCAACCCTCAGTCCTTCTTAACTGCAATCATGCAGACGATGGCTCGAAAAAATGAGTGGCCCCTGGATAAAACGCGCTTGA CTGCTGATGTTACCAAAAAAACAAAGGAAGATTATGGACACCCGCCAAGGGAAGGTGCATACCTCCACGGACTCTTCATGGAGGGCGCCC GCTGGGACACCCAAGCAGGAACCATTGTTGAAGCCCGTCTCAAGGAGCTGGCATGCCCTATGCCGGTCATCTTTGCAAAAGCCACCCCCG TGGACAGACAAGAAACCAAACAGACCTACGAGTGCCCTGTGTATAGAACCAAACTGAGAGGCCCCAGCTACATCTGGACCTTCAGGCTGA >In-frame_PMS2_ENST00000406569_chr7_6048628_-_DNAH11_ENST00000328843_chr7_21813384_+_4472nt ATGGAGCGAGCTGAGAGCTCGAGCCAGTGCACAAAGACTCTATTAGCCTTTTCATGGCACATGTTCACACCACTGTAAATGAAATGAGTA CCAGATATTACCAGAATGAGAGAAGACACAACTATACCACCCCAAAGAGTTTTCTAGAACAAATATCACTGTTTAAGAACCTGTTGAAGA AGAAGCAAAATGAGGTATCCGAGAAAAAAGAACGCCTGGTGAACGGCATCCAAAAGCTAAAAACCACAGCCTCTCAGGTGGGAGATCTAA AAGCCAGACTTGCCTCTCAAGAAGCCGAGCTGCAACTGAGAAATCATGATGCCGAAGCTCTGATCACAAAGATCGGCCTTCAGACGGAGA AAGTGAGCCGGGAAAAGACCATCGCTGATGCTGAGGAGCGAAAGGTGACAGCCATTCAGACTGAAGTGTTCCAGAAACAGAGAGAATGTG AAGCTGACTTACTCAAGGCTGAGCCTGCACTGGTGGCTGCTACAGCTGCACTCAATACACTCAACAGGGTCAACCTCAGTGAGCTGAAAG CCTTTCCCAACCCTCCCATCGCAGTTACCAATGTTACTGCAGCCGTGATGGTCCTTCTGGCTCCTCGGGGAAGAGTGCCCAAAGACCGAA GTTGGAAAGCAGCTAAAGTCTTCATGGGAAAGGTTGATGATTTTTTGCAAGCATTAATTAACTATGACAAAGAGCACATTCCAGAGAACT GTCTAAAAGTGGTGAATGAACACTATTTGAAAGACCCAGAGTTTAATCCAAACCTGATTCGAACCAAATCTTTTGCAGCAGCTGGCCTGT GTGCCTGGGTCATCAACATCATTAAATTCTATGAGGTCTACTGTGATGTGGAGCCAAAACGCCAAGCATTAGCCCAAGCAAACTTAGAAC TGGCTGCAGCTACTGAAAAACTAGAGGCTATCAGGAAAAAGCTTGTGGATCTGGATCGAAATCTGAGCAGACTCACGGCTTCATTTGAAA AAGCAACAGCTGAGAAAGTCCGGTGTCAAGAAGAGGTGAACCAAACCAACAAAACCATCAAATTAGCTAACAGACTTGTCAAGGAACTTG AGGCAAAGAAGATTCGCTGGGGTCAATCCATTAAGTCCTTTGAAGCTCAAGAGAAGACACTCTGTGGAGATGTTCTTCTCACGGCGGCAT TTGTGTCTTACGTCGGACCCTTCACAAGGCAGTATCGCCAGGAGCTGGTGCACTGCAAGTGGGTTCCCTTTCTTCAACAGAAGGTTTCCA TTCCACTAACCGAAGGCCTGGACTTGATATCCATGTTGACGGATGATGCTACAATTGCCGCCTGGAATAACGAAGGACTGCCCAGTGACA GAATGTCCACCGAAAATGCCGCTATCCTAACACACTGTGAGCGCTGGCCTCTGGTGATAGATCCCCAGCAACAGGGAATTAAGTGGATCA AGAATAAGTATGGAATGGACCTGAAAGTCACACATTTGGGCCAGAAAGGGTTTTTGAATGCCATTGAAACTGCTTTGGCCTTTGGTGATG TCATCTTAATTGAAAATCTCGAGGAAACGATAGATCCAGTCCTGGATCCACTACTTGGCAGGAACACAATTAAAAAAGGAAAGTATATCA GGATTGGAGATAAAGAATGTGAATTTAACAAGAACTTTCGCCTTATCCTTCACACAAAATTGGCAAATCCTCACTATAAGCCGGAATTAC AAGCTCAGACAACTCTCCTCAATTTCACAGTCACAGAAGATGGTCTAGAAGCCCAGCTGCTGGCAGAGGTTGTCAGTATTGAAAGGCCAG ATTTGGAGAAACTTAAGTTGGTATTGACAAAGCACCAAAATGATTTTAAAATTGAGCTCAAGTATCTGGAAGACGATCTCCTTTTGCGCC TTTCTGCGGCAGAGGGAAGCTTTCTGGATGACACCAAACTGGTAGAGAGATTGGAGGCAACAAAGACCACCGTGGCAGAGATAGAGCACA AGGTGATTGAAGCCAAAGAAAATGAAAGAAAAATCAACGAGGCCCGAGAATGTTACAGACCAGTGGCAGCAAGAGCATCTCTTCTTTATT TTGTTATTAATGACCTCCAAAAAATCAACCCCCTCTACCAATTCTCTTTGAAGGCTTTTAACGTGCTGTTCCACAGAGCGATCGAGCAGG CTGACAAGGTGGAAGACATGCAGGGACGCATCTCTATCCTGATGGAGAGCATCACCCATGCTGTCTTCCTCTACACCAGCCAGGCGCTGT TTGAGAAGGACAAGCTCACCTTCCTGTCCCAGATGGCTTTTCAGATTTTGTTGAGAAAGAAAGAGATAGACCCTCTTGAATTGGATTTCC TGCTTCGATTCACAGTTGAACACACTCATCTGAGTCCCGTTGACTTCCTAACTTCTCAGTCATGGAGTGCTATCAAGGCAATTGCCGTCA TGGAAGAATTTCGAGGCATAGACCGAGATGTGGAAGGATCTGCCAAGCAGTGGAGGAAGTGGGTAGAATCCGAGTGTCCAGAAAAAGAAA AATTACCTCAAGAATGGAAGAAGAAAAGTTTAATACAGAAGCTGATTCTTCTGAGAGCAATGCGCCCTGACAGAATGACGTATGCTCTCA GAAATTTTGTAGAGGAAAAACTGGGTGCGAAGTATGTGGAGAGGACCAGATTGGACTTAGTTAAAGCATTCGAAGAAAGCAGCCCAGCCA CCCCCATATTCTTCATCCTGTCTCCGGGGGTAGATGCCCTTAAAGACCTGGAGATTCTTGGCAAAAGACTTGGCTTTACAATTGACTCTG GAAAATTCCACAATGTGTCTTTAGGACAAGGTCAGGAGACGGTGGCAGAAGTGGCCCTGGAGAAAGCTTCCAAAGGAGGACACTGGGTCA TCCTCCAAAATGTTCATTTGGTAGCCAAGTGGCTAGGAACCTTGGAGAAGCTCCTTGAAAGATTCAGCCAAGGAAGCCACAGAGATTACA GGGTTTTCATGAGTGCTGAGTCTGCACCTACACCAGATGAGCATATCATCCCTCAAGGACTCCTGGAAAATTCCATTAAGATCACTAATG AACCCCCAACAGGGATGCTGGCCAATTTGCATGCCGCCCTGTACAACTTTGATCAGGATACACTTGAAATATGCTCCAAGGAGCAGGAGT TTAAAAGCATCCTTTTTTCTCTCTGCTACTTCCACGCCTGTGTTGCTGGGAGACTGAGGTTTGGCCCCCAGGGCTGGAGCCGAAGCTATC CTTTTAATCCTGGAGACCTCACCATTTGTGCCAGTGTCCTCTACAACTACTTAGAGGCAAACTCTAAAGTCCCATGGGAAGATCTCCGTT ATCTCTTTGGTGAGATCATGTATGGAGGCCACATCACAGATGACTGGGATCGCAAACTGTGTCGGGTGTATTTAGAAGAATTCATGAATC CATCTCTGACTGAAGATGAACTGATGCTGGCACCAGGTTTTGCTGCCCCACCCTACCTAGATTATGCAGGCTACCACCAGTACATAGAGG AGATGCTTCCTCCAGAAAGCCCGGCACTGTATGGCCTCCACCCAAATGCTGAAATAGAATTCCTGACAGTGACATCCAACACTCTCTTCA GAACTTTGCTGGAGATGCAGCCCAGGAATGCACTCAGTGGTGATGAACTGGGGCAGTCTACAGAAGAAAAGGTTAAGAATGTCTTGGATG ACATTTTGGAGAAACTTCCAGAAGAGTTCAACATGGCAGAGATAATGCAAAAAAATTCAAATAGAAGCCCATATGTTCTTGTTTGCTTCC AAGAATGTGAGAGGATGAATATTCTCATTCGGGAAATACGTATATCACTTGAACAACTGGACCTTAGTTTGAAGGGGGAATTGGCATTAT CTCCTGCTGTGGAAGCCCAGCAGTTTGCATTGAGTTATGACACGGTACCAGACACTTGGAGCAAACTGGCTTATCCTTCTACTTATGGCC TAGCCCAGTGGTTCAATGACCTCCTCCTGCGATGCCGAGAACTCGATACTTGGACACAAGACCTTACCCTTCCGGCTGTCGTGTGGCTCT CCGGCTTCTTCAACCCTCAGTCCTTCTTAACTGCAATCATGCAGACGATGGCTCGAAAAAATGAGTGGCCCCTGGATAAAACGCGCTTGA CTGCTGATGTTACCAAAAAAACAAAGGAAGATTATGGACACCCGCCAAGGGAAGGTGCATACCTCCACGGACTCTTCATGGAGGGCGCCC GCTGGGACACCCAAGCAGGAACCATTGTTGAAGCCCGTCTCAAGGAGCTGGCATGCCCTATGCCGGTCATCTTTGCAAAAGCCACCCCCG TGGACAGACAAGAAACCAAACAGACCTACGAGTGCCCTGTGTATAGAACCAAACTGAGAGGCCCCAGCTACATCTGGACCTTCAGGCTGA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_PMS2_ENST00000265849_chr7_6048628_-_DNAH11_ENST00000409508_chr7_21813384_+_5163nt GGAGCACAACGTCGAAAGCAGCCAATGGGAGTTCAGGAGGCGGAGCGCCTGTGGGAGCCCTGGAGGGAACTTTCCCAGTCCCCGAGGCGG ATCGGGTGTTGCATCCATGGAGCGAGCTGAGAGCTCGAGCCAGTGCACAAAGACTCTATTAGCCTTTTCATGGCACATGTTCACACCACT GTAAATGAAATGAGTACCAGATATTACCAGAATGAGAGAAGACACAACTATACCACCCCAAAGAGTTTTCTAGAACAAATATCACTGTTT AAGAACCTGTTGAAGAAGAAGCAAAATGAGGTATCCGAGAAAAAAGAACGCCTGGTGAACGGCATCCAAAAGCTAAAAACCACAGCCTCT CAGGTGGGAGATCTAAAAGCCAGACTTGCCTCTCAAGAAGCCGAGCTGCAACTGAGAAATCATGATGCCGAAGCTCTGATCACAAAGATC GGCCTTCAGACGGAGAAAGTGAGCCGGGAAAAGACCATCGCTGATGCTGAGGAGCGAAAGGTGACAGCCATTCAGACTGAAGTGTTCCAG AAACAGAGAGAATGTGAAGCTGACTTACTCAAGGCTGAGCCTGCACTGGTGGCTGCTACAGCTGCACTCAATACACTCAACAGGGTCAAC CTCAGTGAGCTGAAAGCCTTTCCCAACCCTCCCATCGCAGTTACCAATGTTACTGCAGCCGTGATGGTCCTTCTGGCTCCTCGGGGAAGA GTGCCCAAAGACCGAAGTTGGAAAGCAGCTAAAGTCTTCATGGGAAAGGTTGATGATTTTTTGCAAGCATTAATTAACTATGACAAAGAG CACATTCCAGAGAACTGTCTAAAAGTGGTGAATGAACACTATTTGAAAGACCCAGAGTTTAATCCAAACCTGATTCGAACCAAATCTTTT GCAGCAGCTGGCCTGTGTGCCTGGGTCATCAACATCATTAAATTCTATGAGGTCTACTGTGATGTGGAGCCAAAACGCCAAGCATTAGCC CAAGCAAACTTAGAACTGGCTGCAGCTACTGAAAAACTAGAGGCTATCAGGAAAAAGCTTGTGGATCTGGATCGAAATCTGAGCAGACTC ACGGCTTCATTTGAAAAAGCAACAGCTGAGAAAGTCCGGTGTCAAGAAGAGGTGAACCAAACCAACAAAACCATCAAATTAGCTAACAGA CTTGTCAAGGAACTTGAGGCAAAGAAGATTCGCTGGGGTCAATCCATTAAGTCCTTTGAAGCTCAAGAGAAGACACTCTGTGGAGATGTT CTTCTCACGGCGGCATTTGTGTCTTACGTCGGACCCTTCACAAGGCAGTATCGCCAGGAGCTGGTGCACTGCAAGTGGGTTCCCTTTCTT CAACAGAAGGTTTCCATTCCACTAACCGAAGGCCTGGACTTGATATCCATGTTGACGGATGATGCTACAATTGCCGCCTGGAATAACGAA GGACTGCCCAGTGACAGAATGTCCACCGAAAATGCCGCTATCCTAACACACTGTGAGCGCTGGCCTCTGGTGATAGATCCCCAGCAACAG GGAATTAAGTGGATCAAGAATAAGTATGGAATGGACCTGAAAGTCACACATTTGGGCCAGAAAGGGTTTTTGAATGCCATTGAAACTGCT TTGGCCTTTGGTGATGTCATCTTAATTGAAAATCTCGAGGAAACGATAGATCCAGTCCTGGATCCACTACTTGGCAGGAACACAATTAAA AAAGGAAAGTATATCAGGATTGGAGATAAAGAATGTGAATTTAACAAGAACTTTCGCCTTATCCTTCACACAAAATTGGCAAATCCTCAC TATAAGCCGGAATTACAAGCTCAGACAACTCTCCTCAATTTCACAGTCACAGAAGATGGTCTAGAAGCCCAGCTGCTGGCAGAGGTTGTC AGTATTGAAAGGCCAGATTTGGAGAAACTTAAGTTGGTATTGACAAAGCACCAAAATGATTTTAAAATTGAGCTCAAGTATCTGGAAGAC GATCTCCTTTTGCGCCTTTCTGCGGCAGAGGGAAGCTTTCTGGATGACACCAAACTGGTAGAGAGATTGGAGGCAACAAAGACCACCGTG GCAGAGATAGAGCACAAGGTGATTGAAGCCAAAGAAAATGAAAGAAAAATCAACGAGGCCCGAGAATGTTACAGACCAGTGGCAGCAAGA GCATCTCTTCTTTATTTTGTTATTAATGACCTCCAAAAAATCAACCCCCTCTACCAATTCTCTTTGAAGGCTTTTAACGTGCTGTTCCAC AGAGCGATCGAGCAGGCTGACAAGGTGGAAGACATGCAGGGACGCATCTCTATCCTGATGGAGAGCATCACCCATGCTGTCTTCCTCTAC ACCAGCCAGGCGCTGTTTGAGAAGGACAAGCTCACCTTCCTGTCCCAGATGGCTTTTCAGATTTTGTTGAGAAAGAAAGAGATAGACCCT CTTGAATTGGATTTCCTGCTTCGATTCACAGTTGAACACACTCATCTGAGTCCCGTTGACTTCCTAACTTCTCAGTCATGGAGTGCTATC AAGGCAATTGCCGTCATGGAAGAATTTCGAGGCATAGACCGAGATGTGGAAGGATCTGCCAAGCAGTGGAGGAAGTGGGTAGAATCCGAG TGTCCAGAAAAAGAAAAATTACCTCAAGAATGGAAGAAGAAAAGTTTAATACAGAAGCTGATTCTTCTGAGAGCAATGCGCCCTGACAGA ATGACGTATGCTCTCAGAAATTTTGTAGAGGAAAAACTGGGTGCGAAGTATGTGGAGAGGACCAGATTGGACTTAGTTAAAGCATTCGAA GAAAGCAGCCCAGCCACCCCCATATTCTTCATCCTGTCTCCGGGGGTAGATGCCCTTAAAGACCTGGAGATTCTTGGCAAAAGACTTGGC TTTACAATTGACTCTGGAAAATTCCACAATGTGTCTTTAGGACAAGGTCAGGAGACGGTGGCAGAAGTGGCCCTGGAGAAAGCTTCCAAA GGAGGACACTGGGTCATCCTCCAAAATGTTCATTTGGTAGCCAAGTGGCTAGGAACCTTGGAGAAGCTCCTTGAAAGATTCAGCCAAGGA AGCCACAGAGATTACAGGGTTTTCATGAGTGCTGAGTCTGCACCTACACCAGATGAGCATATCATCCCTCAAGGACTCCTGGAAAATTCC ATTAAGATCACTAATGAACCCCCAACAGGGATGCTGGCCAATTTGCATGCCGCCCTGTACAACTTTGATCAGGATACACTTGAAATATGC TCCAAGGAGCAGGAGTTTAAAAGCATCCTTTTTTCTCTCTGCTACTTCCACGCCTGTGTTGCTGGGAGACTGAGGTTTGGCCCCCAGGGC TGGAGCCGAAGCTATCCTTTTAATCCTGGAGACCTCACCATTTGTGCCAGTGTCCTCTACAACTACTTAGAGGCAAACTCTAAAGTCCCA TGGGAAGATCTCCGTTATCTCTTTGGTGAGATCATGTATGGAGGCCACATCACAGATGACTGGGATCGCAAACTGTGTCGGGTGTATTTA GAAGAATTCATGAATCCATCTCTGACTGAAGATGAACTGATGCTGGCACCAGGTTTTGCTGCCCCACCCTACCTAGATTATGCAGGCTAC CACCAGTACATAGAGGAGATGCTTCCTCCAGAAAGCCCGGCACTGTATGGCCTCCACCCAAATGCTGAAATAGAATTCCTGACAGTGACA TCCAACACTCTCTTCAGAACTTTGCTGGAGATGCAGCCCAGGAATGCACTCAGTGGTGATGAACTGGGGCAGTCTACAGAAGAAAAGGTT AAGAATGTCTTGGATGACATTTTGGAGAAACTTCCAGAAGAGTTCAACATGGCAGAGATAATGCAAAAAAATTCAAATAGAAGCCCATAT GTTCTTGTTTGCTTCCAAGAATGTGAGAGGATGAATATTCTCATTCGGGAAATACGTATATCACTTGAACAACTGGACCTTAGTTTGAAG GGGGAATTGGCATTATCTCCTGCTGTGGAAGCCCAGCAGTTTGCATTGAGTTATGACACGGTACCAGACACTTGGAGCAAACTGGCTTAT CCTTCTACTTATGGCCTAGCCCAGTGGTTCAATGACCTCCTCCTGCGATGCCGAGAACTCGATACTTGGACACAAGACCTTACCCTTCCG GCTGTCGTGTGGCTCTCCGGCTTCTTCAACCCTCAGTCCTTCTTAACTGCAATCATGCAGACGATGGCTCGAAAAAATGAGTGGCCCCTG GATAAAACGCGCTTGACTGCTGATGTTACCAAAAAAACAAAGGAAGATTATGGACACCCGCCAAGGGAAGGTGCATACCTCCACGGACTC TTCATGGAGGGCGCCCGCTGGGACACCCAAGCAGGAACCATTGTTGAAGCCCGTCTCAAGGAGCTGGCATGCCCTATGCCGGTCATCTTT GCAAAAGCCACCCCCGTGGACAGACAAGAAACCAAACAGACCTACGAGTGCCCTGTGTATAGAACCAAACTGAGAGGCCCCAGCTACATC TGGACCTTCAGGCTGAAGAGCGAAGAGAAGACTGCAAAATGGGTTCTGGCTGGAGTGGCTCTGCTTCTAGAAGCGTAAGGTAACACTGGC ATTCCTCTAGCCTCTGCTGGAGTGCAGTGAGGATTTTCTAGCATGTTGCTGCACTGTTCCCATGCACATTATTCTAACTTTTTAGTAACT CACACGTGCATTCTTTTTTCAACGCTATCCTTAGAGTGAAAGTCAGAAAAAAATACTAGAAACTAACTCAGGGCTGAGCGTGGTGGCACA CGACTGTAATCCCAGTTACTCAGGAGGTAGGAGAATCACTTGAACCTAGGAGGCAAAGGTTGCAGTGAGCCGAGGTTGCACCACTGCACT CCCTCCTGGGCAACAGAACAAGACTCCATCTCAAAAAAAAAAAAGTACATCATAAAAGTACATCATATGTGAACATGCAAAAGCAATGCA GCCGGAAAGAACGGAGATTTTAATTTTTAACAAACAACAAATTAAATTATTAGCCCTTAAACTCTTTCAAAATATAAAAGCAGCAGGCCC CAGGTGAGTCCTGAAGGAAGAGGCTAGCACTCTGTAAGGCCTCCAGTGTCCAGTGTCTACAATGTTGATGGTCCCCTTTTGTTCAGTCAA >In-frame_PMS2_ENST00000265849_chr7_6048628_-_DNAH11_ENST00000328843_chr7_21813384_+_5163nt GGAGCACAACGTCGAAAGCAGCCAATGGGAGTTCAGGAGGCGGAGCGCCTGTGGGAGCCCTGGAGGGAACTTTCCCAGTCCCCGAGGCGG ATCGGGTGTTGCATCCATGGAGCGAGCTGAGAGCTCGAGCCAGTGCACAAAGACTCTATTAGCCTTTTCATGGCACATGTTCACACCACT GTAAATGAAATGAGTACCAGATATTACCAGAATGAGAGAAGACACAACTATACCACCCCAAAGAGTTTTCTAGAACAAATATCACTGTTT AAGAACCTGTTGAAGAAGAAGCAAAATGAGGTATCCGAGAAAAAAGAACGCCTGGTGAACGGCATCCAAAAGCTAAAAACCACAGCCTCT CAGGTGGGAGATCTAAAAGCCAGACTTGCCTCTCAAGAAGCCGAGCTGCAACTGAGAAATCATGATGCCGAAGCTCTGATCACAAAGATC GGCCTTCAGACGGAGAAAGTGAGCCGGGAAAAGACCATCGCTGATGCTGAGGAGCGAAAGGTGACAGCCATTCAGACTGAAGTGTTCCAG AAACAGAGAGAATGTGAAGCTGACTTACTCAAGGCTGAGCCTGCACTGGTGGCTGCTACAGCTGCACTCAATACACTCAACAGGGTCAAC CTCAGTGAGCTGAAAGCCTTTCCCAACCCTCCCATCGCAGTTACCAATGTTACTGCAGCCGTGATGGTCCTTCTGGCTCCTCGGGGAAGA GTGCCCAAAGACCGAAGTTGGAAAGCAGCTAAAGTCTTCATGGGAAAGGTTGATGATTTTTTGCAAGCATTAATTAACTATGACAAAGAG CACATTCCAGAGAACTGTCTAAAAGTGGTGAATGAACACTATTTGAAAGACCCAGAGTTTAATCCAAACCTGATTCGAACCAAATCTTTT GCAGCAGCTGGCCTGTGTGCCTGGGTCATCAACATCATTAAATTCTATGAGGTCTACTGTGATGTGGAGCCAAAACGCCAAGCATTAGCC CAAGCAAACTTAGAACTGGCTGCAGCTACTGAAAAACTAGAGGCTATCAGGAAAAAGCTTGTGGATCTGGATCGAAATCTGAGCAGACTC ACGGCTTCATTTGAAAAAGCAACAGCTGAGAAAGTCCGGTGTCAAGAAGAGGTGAACCAAACCAACAAAACCATCAAATTAGCTAACAGA CTTGTCAAGGAACTTGAGGCAAAGAAGATTCGCTGGGGTCAATCCATTAAGTCCTTTGAAGCTCAAGAGAAGACACTCTGTGGAGATGTT CTTCTCACGGCGGCATTTGTGTCTTACGTCGGACCCTTCACAAGGCAGTATCGCCAGGAGCTGGTGCACTGCAAGTGGGTTCCCTTTCTT CAACAGAAGGTTTCCATTCCACTAACCGAAGGCCTGGACTTGATATCCATGTTGACGGATGATGCTACAATTGCCGCCTGGAATAACGAA GGACTGCCCAGTGACAGAATGTCCACCGAAAATGCCGCTATCCTAACACACTGTGAGCGCTGGCCTCTGGTGATAGATCCCCAGCAACAG GGAATTAAGTGGATCAAGAATAAGTATGGAATGGACCTGAAAGTCACACATTTGGGCCAGAAAGGGTTTTTGAATGCCATTGAAACTGCT TTGGCCTTTGGTGATGTCATCTTAATTGAAAATCTCGAGGAAACGATAGATCCAGTCCTGGATCCACTACTTGGCAGGAACACAATTAAA AAAGGAAAGTATATCAGGATTGGAGATAAAGAATGTGAATTTAACAAGAACTTTCGCCTTATCCTTCACACAAAATTGGCAAATCCTCAC TATAAGCCGGAATTACAAGCTCAGACAACTCTCCTCAATTTCACAGTCACAGAAGATGGTCTAGAAGCCCAGCTGCTGGCAGAGGTTGTC AGTATTGAAAGGCCAGATTTGGAGAAACTTAAGTTGGTATTGACAAAGCACCAAAATGATTTTAAAATTGAGCTCAAGTATCTGGAAGAC GATCTCCTTTTGCGCCTTTCTGCGGCAGAGGGAAGCTTTCTGGATGACACCAAACTGGTAGAGAGATTGGAGGCAACAAAGACCACCGTG GCAGAGATAGAGCACAAGGTGATTGAAGCCAAAGAAAATGAAAGAAAAATCAACGAGGCCCGAGAATGTTACAGACCAGTGGCAGCAAGA GCATCTCTTCTTTATTTTGTTATTAATGACCTCCAAAAAATCAACCCCCTCTACCAATTCTCTTTGAAGGCTTTTAACGTGCTGTTCCAC AGAGCGATCGAGCAGGCTGACAAGGTGGAAGACATGCAGGGACGCATCTCTATCCTGATGGAGAGCATCACCCATGCTGTCTTCCTCTAC ACCAGCCAGGCGCTGTTTGAGAAGGACAAGCTCACCTTCCTGTCCCAGATGGCTTTTCAGATTTTGTTGAGAAAGAAAGAGATAGACCCT CTTGAATTGGATTTCCTGCTTCGATTCACAGTTGAACACACTCATCTGAGTCCCGTTGACTTCCTAACTTCTCAGTCATGGAGTGCTATC AAGGCAATTGCCGTCATGGAAGAATTTCGAGGCATAGACCGAGATGTGGAAGGATCTGCCAAGCAGTGGAGGAAGTGGGTAGAATCCGAG TGTCCAGAAAAAGAAAAATTACCTCAAGAATGGAAGAAGAAAAGTTTAATACAGAAGCTGATTCTTCTGAGAGCAATGCGCCCTGACAGA ATGACGTATGCTCTCAGAAATTTTGTAGAGGAAAAACTGGGTGCGAAGTATGTGGAGAGGACCAGATTGGACTTAGTTAAAGCATTCGAA GAAAGCAGCCCAGCCACCCCCATATTCTTCATCCTGTCTCCGGGGGTAGATGCCCTTAAAGACCTGGAGATTCTTGGCAAAAGACTTGGC TTTACAATTGACTCTGGAAAATTCCACAATGTGTCTTTAGGACAAGGTCAGGAGACGGTGGCAGAAGTGGCCCTGGAGAAAGCTTCCAAA GGAGGACACTGGGTCATCCTCCAAAATGTTCATTTGGTAGCCAAGTGGCTAGGAACCTTGGAGAAGCTCCTTGAAAGATTCAGCCAAGGA AGCCACAGAGATTACAGGGTTTTCATGAGTGCTGAGTCTGCACCTACACCAGATGAGCATATCATCCCTCAAGGACTCCTGGAAAATTCC ATTAAGATCACTAATGAACCCCCAACAGGGATGCTGGCCAATTTGCATGCCGCCCTGTACAACTTTGATCAGGATACACTTGAAATATGC TCCAAGGAGCAGGAGTTTAAAAGCATCCTTTTTTCTCTCTGCTACTTCCACGCCTGTGTTGCTGGGAGACTGAGGTTTGGCCCCCAGGGC TGGAGCCGAAGCTATCCTTTTAATCCTGGAGACCTCACCATTTGTGCCAGTGTCCTCTACAACTACTTAGAGGCAAACTCTAAAGTCCCA TGGGAAGATCTCCGTTATCTCTTTGGTGAGATCATGTATGGAGGCCACATCACAGATGACTGGGATCGCAAACTGTGTCGGGTGTATTTA GAAGAATTCATGAATCCATCTCTGACTGAAGATGAACTGATGCTGGCACCAGGTTTTGCTGCCCCACCCTACCTAGATTATGCAGGCTAC CACCAGTACATAGAGGAGATGCTTCCTCCAGAAAGCCCGGCACTGTATGGCCTCCACCCAAATGCTGAAATAGAATTCCTGACAGTGACA TCCAACACTCTCTTCAGAACTTTGCTGGAGATGCAGCCCAGGAATGCACTCAGTGGTGATGAACTGGGGCAGTCTACAGAAGAAAAGGTT AAGAATGTCTTGGATGACATTTTGGAGAAACTTCCAGAAGAGTTCAACATGGCAGAGATAATGCAAAAAAATTCAAATAGAAGCCCATAT GTTCTTGTTTGCTTCCAAGAATGTGAGAGGATGAATATTCTCATTCGGGAAATACGTATATCACTTGAACAACTGGACCTTAGTTTGAAG GGGGAATTGGCATTATCTCCTGCTGTGGAAGCCCAGCAGTTTGCATTGAGTTATGACACGGTACCAGACACTTGGAGCAAACTGGCTTAT CCTTCTACTTATGGCCTAGCCCAGTGGTTCAATGACCTCCTCCTGCGATGCCGAGAACTCGATACTTGGACACAAGACCTTACCCTTCCG GCTGTCGTGTGGCTCTCCGGCTTCTTCAACCCTCAGTCCTTCTTAACTGCAATCATGCAGACGATGGCTCGAAAAAATGAGTGGCCCCTG GATAAAACGCGCTTGACTGCTGATGTTACCAAAAAAACAAAGGAAGATTATGGACACCCGCCAAGGGAAGGTGCATACCTCCACGGACTC TTCATGGAGGGCGCCCGCTGGGACACCCAAGCAGGAACCATTGTTGAAGCCCGTCTCAAGGAGCTGGCATGCCCTATGCCGGTCATCTTT GCAAAAGCCACCCCCGTGGACAGACAAGAAACCAAACAGACCTACGAGTGCCCTGTGTATAGAACCAAACTGAGAGGCCCCAGCTACATC TGGACCTTCAGGCTGAAGAGCGAAGAGAAGACTGCAAAATGGGTTCTGGCTGGAGTGGCTCTGCTTCTAGAAGCGTAAGGTAACACTGGC ATTCCTCTAGCCTCTGCTGGAGTGCAGTGAGGATTTTCTAGCATGTTGCTGCACTGTTCCCATGCACATTATTCTAACTTTTTAGTAACT CACACGTGCATTCTTTTTTCAACGCTATCCTTAGAGTGAAAGTCAGAAAAAAATACTAGAAACTAACTCAGGGCTGAGCGTGGTGGCACA CGACTGTAATCCCAGTTACTCAGGAGGTAGGAGAATCACTTGAACCTAGGAGGCAAAGGTTGCAGTGAGCCGAGGTTGCACCACTGCACT CCCTCCTGGGCAACAGAACAAGACTCCATCTCAAAAAAAAAAAAGTACATCATAAAAGTACATCATATGTGAACATGCAAAAGCAATGCA GCCGGAAAGAACGGAGATTTTAATTTTTAACAAACAACAAATTAAATTATTAGCCCTTAAACTCTTTCAAAATATAAAAGCAGCAGGCCC CAGGTGAGTCCTGAAGGAAGAGGCTAGCACTCTGTAAGGCCTCCAGTGTCCAGTGTCTACAATGTTGATGGTCCCCTTTTGTTCAGTCAA >In-frame_PMS2_ENST00000382321_chr7_6048628_-_DNAH11_ENST00000409508_chr7_21813384_+_5057nt ATGGAGCGAGCTGAGAGCTCGAGCCAGTGCACAAAGACTCTATTAGCCTTTTCATGGCACATGTTCACACCACTGTAAATGAAATGAGTA CCAGATATTACCAGAATGAGAGAAGACACAACTATACCACCCCAAAGAGTTTTCTAGAACAAATATCACTGTTTAAGAACCTGTTGAAGA AGAAGCAAAATGAGGTATCCGAGAAAAAAGAACGCCTGGTGAACGGCATCCAAAAGCTAAAAACCACAGCCTCTCAGGTGGGAGATCTAA AAGCCAGACTTGCCTCTCAAGAAGCCGAGCTGCAACTGAGAAATCATGATGCCGAAGCTCTGATCACAAAGATCGGCCTTCAGACGGAGA AAGTGAGCCGGGAAAAGACCATCGCTGATGCTGAGGAGCGAAAGGTGACAGCCATTCAGACTGAAGTGTTCCAGAAACAGAGAGAATGTG AAGCTGACTTACTCAAGGCTGAGCCTGCACTGGTGGCTGCTACAGCTGCACTCAATACACTCAACAGGGTCAACCTCAGTGAGCTGAAAG CCTTTCCCAACCCTCCCATCGCAGTTACCAATGTTACTGCAGCCGTGATGGTCCTTCTGGCTCCTCGGGGAAGAGTGCCCAAAGACCGAA GTTGGAAAGCAGCTAAAGTCTTCATGGGAAAGGTTGATGATTTTTTGCAAGCATTAATTAACTATGACAAAGAGCACATTCCAGAGAACT GTCTAAAAGTGGTGAATGAACACTATTTGAAAGACCCAGAGTTTAATCCAAACCTGATTCGAACCAAATCTTTTGCAGCAGCTGGCCTGT GTGCCTGGGTCATCAACATCATTAAATTCTATGAGGTCTACTGTGATGTGGAGCCAAAACGCCAAGCATTAGCCCAAGCAAACTTAGAAC TGGCTGCAGCTACTGAAAAACTAGAGGCTATCAGGAAAAAGCTTGTGGATCTGGATCGAAATCTGAGCAGACTCACGGCTTCATTTGAAA AAGCAACAGCTGAGAAAGTCCGGTGTCAAGAAGAGGTGAACCAAACCAACAAAACCATCAAATTAGCTAACAGACTTGTCAAGGAACTTG AGGCAAAGAAGATTCGCTGGGGTCAATCCATTAAGTCCTTTGAAGCTCAAGAGAAGACACTCTGTGGAGATGTTCTTCTCACGGCGGCAT TTGTGTCTTACGTCGGACCCTTCACAAGGCAGTATCGCCAGGAGCTGGTGCACTGCAAGTGGGTTCCCTTTCTTCAACAGAAGGTTTCCA TTCCACTAACCGAAGGCCTGGACTTGATATCCATGTTGACGGATGATGCTACAATTGCCGCCTGGAATAACGAAGGACTGCCCAGTGACA GAATGTCCACCGAAAATGCCGCTATCCTAACACACTGTGAGCGCTGGCCTCTGGTGATAGATCCCCAGCAACAGGGAATTAAGTGGATCA AGAATAAGTATGGAATGGACCTGAAAGTCACACATTTGGGCCAGAAAGGGTTTTTGAATGCCATTGAAACTGCTTTGGCCTTTGGTGATG TCATCTTAATTGAAAATCTCGAGGAAACGATAGATCCAGTCCTGGATCCACTACTTGGCAGGAACACAATTAAAAAAGGAAAGTATATCA GGATTGGAGATAAAGAATGTGAATTTAACAAGAACTTTCGCCTTATCCTTCACACAAAATTGGCAAATCCTCACTATAAGCCGGAATTAC AAGCTCAGACAACTCTCCTCAATTTCACAGTCACAGAAGATGGTCTAGAAGCCCAGCTGCTGGCAGAGGTTGTCAGTATTGAAAGGCCAG ATTTGGAGAAACTTAAGTTGGTATTGACAAAGCACCAAAATGATTTTAAAATTGAGCTCAAGTATCTGGAAGACGATCTCCTTTTGCGCC TTTCTGCGGCAGAGGGAAGCTTTCTGGATGACACCAAACTGGTAGAGAGATTGGAGGCAACAAAGACCACCGTGGCAGAGATAGAGCACA AGGTGATTGAAGCCAAAGAAAATGAAAGAAAAATCAACGAGGCCCGAGAATGTTACAGACCAGTGGCAGCAAGAGCATCTCTTCTTTATT TTGTTATTAATGACCTCCAAAAAATCAACCCCCTCTACCAATTCTCTTTGAAGGCTTTTAACGTGCTGTTCCACAGAGCGATCGAGCAGG CTGACAAGGTGGAAGACATGCAGGGACGCATCTCTATCCTGATGGAGAGCATCACCCATGCTGTCTTCCTCTACACCAGCCAGGCGCTGT TTGAGAAGGACAAGCTCACCTTCCTGTCCCAGATGGCTTTTCAGATTTTGTTGAGAAAGAAAGAGATAGACCCTCTTGAATTGGATTTCC TGCTTCGATTCACAGTTGAACACACTCATCTGAGTCCCGTTGACTTCCTAACTTCTCAGTCATGGAGTGCTATCAAGGCAATTGCCGTCA TGGAAGAATTTCGAGGCATAGACCGAGATGTGGAAGGATCTGCCAAGCAGTGGAGGAAGTGGGTAGAATCCGAGTGTCCAGAAAAAGAAA AATTACCTCAAGAATGGAAGAAGAAAAGTTTAATACAGAAGCTGATTCTTCTGAGAGCAATGCGCCCTGACAGAATGACGTATGCTCTCA GAAATTTTGTAGAGGAAAAACTGGGTGCGAAGTATGTGGAGAGGACCAGATTGGACTTAGTTAAAGCATTCGAAGAAAGCAGCCCAGCCA CCCCCATATTCTTCATCCTGTCTCCGGGGGTAGATGCCCTTAAAGACCTGGAGATTCTTGGCAAAAGACTTGGCTTTACAATTGACTCTG GAAAATTCCACAATGTGTCTTTAGGACAAGGTCAGGAGACGGTGGCAGAAGTGGCCCTGGAGAAAGCTTCCAAAGGAGGACACTGGGTCA TCCTCCAAAATGTTCATTTGGTAGCCAAGTGGCTAGGAACCTTGGAGAAGCTCCTTGAAAGATTCAGCCAAGGAAGCCACAGAGATTACA GGGTTTTCATGAGTGCTGAGTCTGCACCTACACCAGATGAGCATATCATCCCTCAAGGACTCCTGGAAAATTCCATTAAGATCACTAATG AACCCCCAACAGGGATGCTGGCCAATTTGCATGCCGCCCTGTACAACTTTGATCAGGATACACTTGAAATATGCTCCAAGGAGCAGGAGT TTAAAAGCATCCTTTTTTCTCTCTGCTACTTCCACGCCTGTGTTGCTGGGAGACTGAGGTTTGGCCCCCAGGGCTGGAGCCGAAGCTATC CTTTTAATCCTGGAGACCTCACCATTTGTGCCAGTGTCCTCTACAACTACTTAGAGGCAAACTCTAAAGTCCCATGGGAAGATCTCCGTT ATCTCTTTGGTGAGATCATGTATGGAGGCCACATCACAGATGACTGGGATCGCAAACTGTGTCGGGTGTATTTAGAAGAATTCATGAATC CATCTCTGACTGAAGATGAACTGATGCTGGCACCAGGTTTTGCTGCCCCACCCTACCTAGATTATGCAGGCTACCACCAGTACATAGAGG AGATGCTTCCTCCAGAAAGCCCGGCACTGTATGGCCTCCACCCAAATGCTGAAATAGAATTCCTGACAGTGACATCCAACACTCTCTTCA GAACTTTGCTGGAGATGCAGCCCAGGAATGCACTCAGTGGTGATGAACTGGGGCAGTCTACAGAAGAAAAGGTTAAGAATGTCTTGGATG ACATTTTGGAGAAACTTCCAGAAGAGTTCAACATGGCAGAGATAATGCAAAAAAATTCAAATAGAAGCCCATATGTTCTTGTTTGCTTCC AAGAATGTGAGAGGATGAATATTCTCATTCGGGAAATACGTATATCACTTGAACAACTGGACCTTAGTTTGAAGGGGGAATTGGCATTAT CTCCTGCTGTGGAAGCCCAGCAGTTTGCATTGAGTTATGACACGGTACCAGACACTTGGAGCAAACTGGCTTATCCTTCTACTTATGGCC TAGCCCAGTGGTTCAATGACCTCCTCCTGCGATGCCGAGAACTCGATACTTGGACACAAGACCTTACCCTTCCGGCTGTCGTGTGGCTCT CCGGCTTCTTCAACCCTCAGTCCTTCTTAACTGCAATCATGCAGACGATGGCTCGAAAAAATGAGTGGCCCCTGGATAAAACGCGCTTGA CTGCTGATGTTACCAAAAAAACAAAGGAAGATTATGGACACCCGCCAAGGGAAGGTGCATACCTCCACGGACTCTTCATGGAGGGCGCCC GCTGGGACACCCAAGCAGGAACCATTGTTGAAGCCCGTCTCAAGGAGCTGGCATGCCCTATGCCGGTCATCTTTGCAAAAGCCACCCCCG TGGACAGACAAGAAACCAAACAGACCTACGAGTGCCCTGTGTATAGAACCAAACTGAGAGGCCCCAGCTACATCTGGACCTTCAGGCTGA AGAGCGAAGAGAAGACTGCAAAATGGGTTCTGGCTGGAGTGGCTCTGCTTCTAGAAGCGTAAGGTAACACTGGCATTCCTCTAGCCTCTG CTGGAGTGCAGTGAGGATTTTCTAGCATGTTGCTGCACTGTTCCCATGCACATTATTCTAACTTTTTAGTAACTCACACGTGCATTCTTT TTTCAACGCTATCCTTAGAGTGAAAGTCAGAAAAAAATACTAGAAACTAACTCAGGGCTGAGCGTGGTGGCACACGACTGTAATCCCAGT TACTCAGGAGGTAGGAGAATCACTTGAACCTAGGAGGCAAAGGTTGCAGTGAGCCGAGGTTGCACCACTGCACTCCCTCCTGGGCAACAG AACAAGACTCCATCTCAAAAAAAAAAAAGTACATCATAAAAGTACATCATATGTGAACATGCAAAAGCAATGCAGCCGGAAAGAACGGAG ATTTTAATTTTTAACAAACAACAAATTAAATTATTAGCCCTTAAACTCTTTCAAAATATAAAAGCAGCAGGCCCCAGGTGAGTCCTGAAG GAAGAGGCTAGCACTCTGTAAGGCCTCCAGTGTCCAGTGTCTACAATGTTGATGGTCCCCTTTTGTTCAGTCAAGTTTTAATAAAAATAA >In-frame_PMS2_ENST00000382321_chr7_6048628_-_DNAH11_ENST00000328843_chr7_21813384_+_5057nt ATGGAGCGAGCTGAGAGCTCGAGCCAGTGCACAAAGACTCTATTAGCCTTTTCATGGCACATGTTCACACCACTGTAAATGAAATGAGTA CCAGATATTACCAGAATGAGAGAAGACACAACTATACCACCCCAAAGAGTTTTCTAGAACAAATATCACTGTTTAAGAACCTGTTGAAGA AGAAGCAAAATGAGGTATCCGAGAAAAAAGAACGCCTGGTGAACGGCATCCAAAAGCTAAAAACCACAGCCTCTCAGGTGGGAGATCTAA AAGCCAGACTTGCCTCTCAAGAAGCCGAGCTGCAACTGAGAAATCATGATGCCGAAGCTCTGATCACAAAGATCGGCCTTCAGACGGAGA AAGTGAGCCGGGAAAAGACCATCGCTGATGCTGAGGAGCGAAAGGTGACAGCCATTCAGACTGAAGTGTTCCAGAAACAGAGAGAATGTG AAGCTGACTTACTCAAGGCTGAGCCTGCACTGGTGGCTGCTACAGCTGCACTCAATACACTCAACAGGGTCAACCTCAGTGAGCTGAAAG CCTTTCCCAACCCTCCCATCGCAGTTACCAATGTTACTGCAGCCGTGATGGTCCTTCTGGCTCCTCGGGGAAGAGTGCCCAAAGACCGAA GTTGGAAAGCAGCTAAAGTCTTCATGGGAAAGGTTGATGATTTTTTGCAAGCATTAATTAACTATGACAAAGAGCACATTCCAGAGAACT GTCTAAAAGTGGTGAATGAACACTATTTGAAAGACCCAGAGTTTAATCCAAACCTGATTCGAACCAAATCTTTTGCAGCAGCTGGCCTGT GTGCCTGGGTCATCAACATCATTAAATTCTATGAGGTCTACTGTGATGTGGAGCCAAAACGCCAAGCATTAGCCCAAGCAAACTTAGAAC TGGCTGCAGCTACTGAAAAACTAGAGGCTATCAGGAAAAAGCTTGTGGATCTGGATCGAAATCTGAGCAGACTCACGGCTTCATTTGAAA AAGCAACAGCTGAGAAAGTCCGGTGTCAAGAAGAGGTGAACCAAACCAACAAAACCATCAAATTAGCTAACAGACTTGTCAAGGAACTTG AGGCAAAGAAGATTCGCTGGGGTCAATCCATTAAGTCCTTTGAAGCTCAAGAGAAGACACTCTGTGGAGATGTTCTTCTCACGGCGGCAT TTGTGTCTTACGTCGGACCCTTCACAAGGCAGTATCGCCAGGAGCTGGTGCACTGCAAGTGGGTTCCCTTTCTTCAACAGAAGGTTTCCA TTCCACTAACCGAAGGCCTGGACTTGATATCCATGTTGACGGATGATGCTACAATTGCCGCCTGGAATAACGAAGGACTGCCCAGTGACA GAATGTCCACCGAAAATGCCGCTATCCTAACACACTGTGAGCGCTGGCCTCTGGTGATAGATCCCCAGCAACAGGGAATTAAGTGGATCA AGAATAAGTATGGAATGGACCTGAAAGTCACACATTTGGGCCAGAAAGGGTTTTTGAATGCCATTGAAACTGCTTTGGCCTTTGGTGATG TCATCTTAATTGAAAATCTCGAGGAAACGATAGATCCAGTCCTGGATCCACTACTTGGCAGGAACACAATTAAAAAAGGAAAGTATATCA GGATTGGAGATAAAGAATGTGAATTTAACAAGAACTTTCGCCTTATCCTTCACACAAAATTGGCAAATCCTCACTATAAGCCGGAATTAC AAGCTCAGACAACTCTCCTCAATTTCACAGTCACAGAAGATGGTCTAGAAGCCCAGCTGCTGGCAGAGGTTGTCAGTATTGAAAGGCCAG ATTTGGAGAAACTTAAGTTGGTATTGACAAAGCACCAAAATGATTTTAAAATTGAGCTCAAGTATCTGGAAGACGATCTCCTTTTGCGCC TTTCTGCGGCAGAGGGAAGCTTTCTGGATGACACCAAACTGGTAGAGAGATTGGAGGCAACAAAGACCACCGTGGCAGAGATAGAGCACA AGGTGATTGAAGCCAAAGAAAATGAAAGAAAAATCAACGAGGCCCGAGAATGTTACAGACCAGTGGCAGCAAGAGCATCTCTTCTTTATT TTGTTATTAATGACCTCCAAAAAATCAACCCCCTCTACCAATTCTCTTTGAAGGCTTTTAACGTGCTGTTCCACAGAGCGATCGAGCAGG CTGACAAGGTGGAAGACATGCAGGGACGCATCTCTATCCTGATGGAGAGCATCACCCATGCTGTCTTCCTCTACACCAGCCAGGCGCTGT TTGAGAAGGACAAGCTCACCTTCCTGTCCCAGATGGCTTTTCAGATTTTGTTGAGAAAGAAAGAGATAGACCCTCTTGAATTGGATTTCC TGCTTCGATTCACAGTTGAACACACTCATCTGAGTCCCGTTGACTTCCTAACTTCTCAGTCATGGAGTGCTATCAAGGCAATTGCCGTCA TGGAAGAATTTCGAGGCATAGACCGAGATGTGGAAGGATCTGCCAAGCAGTGGAGGAAGTGGGTAGAATCCGAGTGTCCAGAAAAAGAAA AATTACCTCAAGAATGGAAGAAGAAAAGTTTAATACAGAAGCTGATTCTTCTGAGAGCAATGCGCCCTGACAGAATGACGTATGCTCTCA GAAATTTTGTAGAGGAAAAACTGGGTGCGAAGTATGTGGAGAGGACCAGATTGGACTTAGTTAAAGCATTCGAAGAAAGCAGCCCAGCCA CCCCCATATTCTTCATCCTGTCTCCGGGGGTAGATGCCCTTAAAGACCTGGAGATTCTTGGCAAAAGACTTGGCTTTACAATTGACTCTG GAAAATTCCACAATGTGTCTTTAGGACAAGGTCAGGAGACGGTGGCAGAAGTGGCCCTGGAGAAAGCTTCCAAAGGAGGACACTGGGTCA TCCTCCAAAATGTTCATTTGGTAGCCAAGTGGCTAGGAACCTTGGAGAAGCTCCTTGAAAGATTCAGCCAAGGAAGCCACAGAGATTACA GGGTTTTCATGAGTGCTGAGTCTGCACCTACACCAGATGAGCATATCATCCCTCAAGGACTCCTGGAAAATTCCATTAAGATCACTAATG AACCCCCAACAGGGATGCTGGCCAATTTGCATGCCGCCCTGTACAACTTTGATCAGGATACACTTGAAATATGCTCCAAGGAGCAGGAGT TTAAAAGCATCCTTTTTTCTCTCTGCTACTTCCACGCCTGTGTTGCTGGGAGACTGAGGTTTGGCCCCCAGGGCTGGAGCCGAAGCTATC CTTTTAATCCTGGAGACCTCACCATTTGTGCCAGTGTCCTCTACAACTACTTAGAGGCAAACTCTAAAGTCCCATGGGAAGATCTCCGTT ATCTCTTTGGTGAGATCATGTATGGAGGCCACATCACAGATGACTGGGATCGCAAACTGTGTCGGGTGTATTTAGAAGAATTCATGAATC CATCTCTGACTGAAGATGAACTGATGCTGGCACCAGGTTTTGCTGCCCCACCCTACCTAGATTATGCAGGCTACCACCAGTACATAGAGG AGATGCTTCCTCCAGAAAGCCCGGCACTGTATGGCCTCCACCCAAATGCTGAAATAGAATTCCTGACAGTGACATCCAACACTCTCTTCA GAACTTTGCTGGAGATGCAGCCCAGGAATGCACTCAGTGGTGATGAACTGGGGCAGTCTACAGAAGAAAAGGTTAAGAATGTCTTGGATG ACATTTTGGAGAAACTTCCAGAAGAGTTCAACATGGCAGAGATAATGCAAAAAAATTCAAATAGAAGCCCATATGTTCTTGTTTGCTTCC AAGAATGTGAGAGGATGAATATTCTCATTCGGGAAATACGTATATCACTTGAACAACTGGACCTTAGTTTGAAGGGGGAATTGGCATTAT CTCCTGCTGTGGAAGCCCAGCAGTTTGCATTGAGTTATGACACGGTACCAGACACTTGGAGCAAACTGGCTTATCCTTCTACTTATGGCC TAGCCCAGTGGTTCAATGACCTCCTCCTGCGATGCCGAGAACTCGATACTTGGACACAAGACCTTACCCTTCCGGCTGTCGTGTGGCTCT CCGGCTTCTTCAACCCTCAGTCCTTCTTAACTGCAATCATGCAGACGATGGCTCGAAAAAATGAGTGGCCCCTGGATAAAACGCGCTTGA CTGCTGATGTTACCAAAAAAACAAAGGAAGATTATGGACACCCGCCAAGGGAAGGTGCATACCTCCACGGACTCTTCATGGAGGGCGCCC GCTGGGACACCCAAGCAGGAACCATTGTTGAAGCCCGTCTCAAGGAGCTGGCATGCCCTATGCCGGTCATCTTTGCAAAAGCCACCCCCG TGGACAGACAAGAAACCAAACAGACCTACGAGTGCCCTGTGTATAGAACCAAACTGAGAGGCCCCAGCTACATCTGGACCTTCAGGCTGA AGAGCGAAGAGAAGACTGCAAAATGGGTTCTGGCTGGAGTGGCTCTGCTTCTAGAAGCGTAAGGTAACACTGGCATTCCTCTAGCCTCTG CTGGAGTGCAGTGAGGATTTTCTAGCATGTTGCTGCACTGTTCCCATGCACATTATTCTAACTTTTTAGTAACTCACACGTGCATTCTTT TTTCAACGCTATCCTTAGAGTGAAAGTCAGAAAAAAATACTAGAAACTAACTCAGGGCTGAGCGTGGTGGCACACGACTGTAATCCCAGT TACTCAGGAGGTAGGAGAATCACTTGAACCTAGGAGGCAAAGGTTGCAGTGAGCCGAGGTTGCACCACTGCACTCCCTCCTGGGCAACAG AACAAGACTCCATCTCAAAAAAAAAAAAGTACATCATAAAAGTACATCATATGTGAACATGCAAAAGCAATGCAGCCGGAAAGAACGGAG ATTTTAATTTTTAACAAACAACAAATTAAATTATTAGCCCTTAAACTCTTTCAAAATATAAAAGCAGCAGGCCCCAGGTGAGTCCTGAAG GAAGAGGCTAGCACTCTGTAAGGCCTCCAGTGTCCAGTGTCTACAATGTTGATGGTCCCCTTTTGTTCAGTCAAGTTTTAATAAAAATAA >In-frame_PMS2_ENST00000406569_chr7_6048628_-_DNAH11_ENST00000409508_chr7_21813384_+_5057nt ATGGAGCGAGCTGAGAGCTCGAGCCAGTGCACAAAGACTCTATTAGCCTTTTCATGGCACATGTTCACACCACTGTAAATGAAATGAGTA CCAGATATTACCAGAATGAGAGAAGACACAACTATACCACCCCAAAGAGTTTTCTAGAACAAATATCACTGTTTAAGAACCTGTTGAAGA AGAAGCAAAATGAGGTATCCGAGAAAAAAGAACGCCTGGTGAACGGCATCCAAAAGCTAAAAACCACAGCCTCTCAGGTGGGAGATCTAA AAGCCAGACTTGCCTCTCAAGAAGCCGAGCTGCAACTGAGAAATCATGATGCCGAAGCTCTGATCACAAAGATCGGCCTTCAGACGGAGA AAGTGAGCCGGGAAAAGACCATCGCTGATGCTGAGGAGCGAAAGGTGACAGCCATTCAGACTGAAGTGTTCCAGAAACAGAGAGAATGTG AAGCTGACTTACTCAAGGCTGAGCCTGCACTGGTGGCTGCTACAGCTGCACTCAATACACTCAACAGGGTCAACCTCAGTGAGCTGAAAG CCTTTCCCAACCCTCCCATCGCAGTTACCAATGTTACTGCAGCCGTGATGGTCCTTCTGGCTCCTCGGGGAAGAGTGCCCAAAGACCGAA GTTGGAAAGCAGCTAAAGTCTTCATGGGAAAGGTTGATGATTTTTTGCAAGCATTAATTAACTATGACAAAGAGCACATTCCAGAGAACT GTCTAAAAGTGGTGAATGAACACTATTTGAAAGACCCAGAGTTTAATCCAAACCTGATTCGAACCAAATCTTTTGCAGCAGCTGGCCTGT GTGCCTGGGTCATCAACATCATTAAATTCTATGAGGTCTACTGTGATGTGGAGCCAAAACGCCAAGCATTAGCCCAAGCAAACTTAGAAC TGGCTGCAGCTACTGAAAAACTAGAGGCTATCAGGAAAAAGCTTGTGGATCTGGATCGAAATCTGAGCAGACTCACGGCTTCATTTGAAA AAGCAACAGCTGAGAAAGTCCGGTGTCAAGAAGAGGTGAACCAAACCAACAAAACCATCAAATTAGCTAACAGACTTGTCAAGGAACTTG AGGCAAAGAAGATTCGCTGGGGTCAATCCATTAAGTCCTTTGAAGCTCAAGAGAAGACACTCTGTGGAGATGTTCTTCTCACGGCGGCAT TTGTGTCTTACGTCGGACCCTTCACAAGGCAGTATCGCCAGGAGCTGGTGCACTGCAAGTGGGTTCCCTTTCTTCAACAGAAGGTTTCCA TTCCACTAACCGAAGGCCTGGACTTGATATCCATGTTGACGGATGATGCTACAATTGCCGCCTGGAATAACGAAGGACTGCCCAGTGACA GAATGTCCACCGAAAATGCCGCTATCCTAACACACTGTGAGCGCTGGCCTCTGGTGATAGATCCCCAGCAACAGGGAATTAAGTGGATCA AGAATAAGTATGGAATGGACCTGAAAGTCACACATTTGGGCCAGAAAGGGTTTTTGAATGCCATTGAAACTGCTTTGGCCTTTGGTGATG TCATCTTAATTGAAAATCTCGAGGAAACGATAGATCCAGTCCTGGATCCACTACTTGGCAGGAACACAATTAAAAAAGGAAAGTATATCA GGATTGGAGATAAAGAATGTGAATTTAACAAGAACTTTCGCCTTATCCTTCACACAAAATTGGCAAATCCTCACTATAAGCCGGAATTAC AAGCTCAGACAACTCTCCTCAATTTCACAGTCACAGAAGATGGTCTAGAAGCCCAGCTGCTGGCAGAGGTTGTCAGTATTGAAAGGCCAG ATTTGGAGAAACTTAAGTTGGTATTGACAAAGCACCAAAATGATTTTAAAATTGAGCTCAAGTATCTGGAAGACGATCTCCTTTTGCGCC TTTCTGCGGCAGAGGGAAGCTTTCTGGATGACACCAAACTGGTAGAGAGATTGGAGGCAACAAAGACCACCGTGGCAGAGATAGAGCACA AGGTGATTGAAGCCAAAGAAAATGAAAGAAAAATCAACGAGGCCCGAGAATGTTACAGACCAGTGGCAGCAAGAGCATCTCTTCTTTATT TTGTTATTAATGACCTCCAAAAAATCAACCCCCTCTACCAATTCTCTTTGAAGGCTTTTAACGTGCTGTTCCACAGAGCGATCGAGCAGG CTGACAAGGTGGAAGACATGCAGGGACGCATCTCTATCCTGATGGAGAGCATCACCCATGCTGTCTTCCTCTACACCAGCCAGGCGCTGT TTGAGAAGGACAAGCTCACCTTCCTGTCCCAGATGGCTTTTCAGATTTTGTTGAGAAAGAAAGAGATAGACCCTCTTGAATTGGATTTCC TGCTTCGATTCACAGTTGAACACACTCATCTGAGTCCCGTTGACTTCCTAACTTCTCAGTCATGGAGTGCTATCAAGGCAATTGCCGTCA TGGAAGAATTTCGAGGCATAGACCGAGATGTGGAAGGATCTGCCAAGCAGTGGAGGAAGTGGGTAGAATCCGAGTGTCCAGAAAAAGAAA AATTACCTCAAGAATGGAAGAAGAAAAGTTTAATACAGAAGCTGATTCTTCTGAGAGCAATGCGCCCTGACAGAATGACGTATGCTCTCA GAAATTTTGTAGAGGAAAAACTGGGTGCGAAGTATGTGGAGAGGACCAGATTGGACTTAGTTAAAGCATTCGAAGAAAGCAGCCCAGCCA CCCCCATATTCTTCATCCTGTCTCCGGGGGTAGATGCCCTTAAAGACCTGGAGATTCTTGGCAAAAGACTTGGCTTTACAATTGACTCTG GAAAATTCCACAATGTGTCTTTAGGACAAGGTCAGGAGACGGTGGCAGAAGTGGCCCTGGAGAAAGCTTCCAAAGGAGGACACTGGGTCA TCCTCCAAAATGTTCATTTGGTAGCCAAGTGGCTAGGAACCTTGGAGAAGCTCCTTGAAAGATTCAGCCAAGGAAGCCACAGAGATTACA GGGTTTTCATGAGTGCTGAGTCTGCACCTACACCAGATGAGCATATCATCCCTCAAGGACTCCTGGAAAATTCCATTAAGATCACTAATG AACCCCCAACAGGGATGCTGGCCAATTTGCATGCCGCCCTGTACAACTTTGATCAGGATACACTTGAAATATGCTCCAAGGAGCAGGAGT TTAAAAGCATCCTTTTTTCTCTCTGCTACTTCCACGCCTGTGTTGCTGGGAGACTGAGGTTTGGCCCCCAGGGCTGGAGCCGAAGCTATC CTTTTAATCCTGGAGACCTCACCATTTGTGCCAGTGTCCTCTACAACTACTTAGAGGCAAACTCTAAAGTCCCATGGGAAGATCTCCGTT ATCTCTTTGGTGAGATCATGTATGGAGGCCACATCACAGATGACTGGGATCGCAAACTGTGTCGGGTGTATTTAGAAGAATTCATGAATC CATCTCTGACTGAAGATGAACTGATGCTGGCACCAGGTTTTGCTGCCCCACCCTACCTAGATTATGCAGGCTACCACCAGTACATAGAGG AGATGCTTCCTCCAGAAAGCCCGGCACTGTATGGCCTCCACCCAAATGCTGAAATAGAATTCCTGACAGTGACATCCAACACTCTCTTCA GAACTTTGCTGGAGATGCAGCCCAGGAATGCACTCAGTGGTGATGAACTGGGGCAGTCTACAGAAGAAAAGGTTAAGAATGTCTTGGATG ACATTTTGGAGAAACTTCCAGAAGAGTTCAACATGGCAGAGATAATGCAAAAAAATTCAAATAGAAGCCCATATGTTCTTGTTTGCTTCC AAGAATGTGAGAGGATGAATATTCTCATTCGGGAAATACGTATATCACTTGAACAACTGGACCTTAGTTTGAAGGGGGAATTGGCATTAT CTCCTGCTGTGGAAGCCCAGCAGTTTGCATTGAGTTATGACACGGTACCAGACACTTGGAGCAAACTGGCTTATCCTTCTACTTATGGCC TAGCCCAGTGGTTCAATGACCTCCTCCTGCGATGCCGAGAACTCGATACTTGGACACAAGACCTTACCCTTCCGGCTGTCGTGTGGCTCT CCGGCTTCTTCAACCCTCAGTCCTTCTTAACTGCAATCATGCAGACGATGGCTCGAAAAAATGAGTGGCCCCTGGATAAAACGCGCTTGA CTGCTGATGTTACCAAAAAAACAAAGGAAGATTATGGACACCCGCCAAGGGAAGGTGCATACCTCCACGGACTCTTCATGGAGGGCGCCC GCTGGGACACCCAAGCAGGAACCATTGTTGAAGCCCGTCTCAAGGAGCTGGCATGCCCTATGCCGGTCATCTTTGCAAAAGCCACCCCCG TGGACAGACAAGAAACCAAACAGACCTACGAGTGCCCTGTGTATAGAACCAAACTGAGAGGCCCCAGCTACATCTGGACCTTCAGGCTGA AGAGCGAAGAGAAGACTGCAAAATGGGTTCTGGCTGGAGTGGCTCTGCTTCTAGAAGCGTAAGGTAACACTGGCATTCCTCTAGCCTCTG CTGGAGTGCAGTGAGGATTTTCTAGCATGTTGCTGCACTGTTCCCATGCACATTATTCTAACTTTTTAGTAACTCACACGTGCATTCTTT TTTCAACGCTATCCTTAGAGTGAAAGTCAGAAAAAAATACTAGAAACTAACTCAGGGCTGAGCGTGGTGGCACACGACTGTAATCCCAGT TACTCAGGAGGTAGGAGAATCACTTGAACCTAGGAGGCAAAGGTTGCAGTGAGCCGAGGTTGCACCACTGCACTCCCTCCTGGGCAACAG AACAAGACTCCATCTCAAAAAAAAAAAAGTACATCATAAAAGTACATCATATGTGAACATGCAAAAGCAATGCAGCCGGAAAGAACGGAG ATTTTAATTTTTAACAAACAACAAATTAAATTATTAGCCCTTAAACTCTTTCAAAATATAAAAGCAGCAGGCCCCAGGTGAGTCCTGAAG GAAGAGGCTAGCACTCTGTAAGGCCTCCAGTGTCCAGTGTCTACAATGTTGATGGTCCCCTTTTGTTCAGTCAAGTTTTAATAAAAATAA >In-frame_PMS2_ENST00000406569_chr7_6048628_-_DNAH11_ENST00000328843_chr7_21813384_+_5057nt ATGGAGCGAGCTGAGAGCTCGAGCCAGTGCACAAAGACTCTATTAGCCTTTTCATGGCACATGTTCACACCACTGTAAATGAAATGAGTA CCAGATATTACCAGAATGAGAGAAGACACAACTATACCACCCCAAAGAGTTTTCTAGAACAAATATCACTGTTTAAGAACCTGTTGAAGA AGAAGCAAAATGAGGTATCCGAGAAAAAAGAACGCCTGGTGAACGGCATCCAAAAGCTAAAAACCACAGCCTCTCAGGTGGGAGATCTAA AAGCCAGACTTGCCTCTCAAGAAGCCGAGCTGCAACTGAGAAATCATGATGCCGAAGCTCTGATCACAAAGATCGGCCTTCAGACGGAGA AAGTGAGCCGGGAAAAGACCATCGCTGATGCTGAGGAGCGAAAGGTGACAGCCATTCAGACTGAAGTGTTCCAGAAACAGAGAGAATGTG AAGCTGACTTACTCAAGGCTGAGCCTGCACTGGTGGCTGCTACAGCTGCACTCAATACACTCAACAGGGTCAACCTCAGTGAGCTGAAAG CCTTTCCCAACCCTCCCATCGCAGTTACCAATGTTACTGCAGCCGTGATGGTCCTTCTGGCTCCTCGGGGAAGAGTGCCCAAAGACCGAA GTTGGAAAGCAGCTAAAGTCTTCATGGGAAAGGTTGATGATTTTTTGCAAGCATTAATTAACTATGACAAAGAGCACATTCCAGAGAACT GTCTAAAAGTGGTGAATGAACACTATTTGAAAGACCCAGAGTTTAATCCAAACCTGATTCGAACCAAATCTTTTGCAGCAGCTGGCCTGT GTGCCTGGGTCATCAACATCATTAAATTCTATGAGGTCTACTGTGATGTGGAGCCAAAACGCCAAGCATTAGCCCAAGCAAACTTAGAAC TGGCTGCAGCTACTGAAAAACTAGAGGCTATCAGGAAAAAGCTTGTGGATCTGGATCGAAATCTGAGCAGACTCACGGCTTCATTTGAAA AAGCAACAGCTGAGAAAGTCCGGTGTCAAGAAGAGGTGAACCAAACCAACAAAACCATCAAATTAGCTAACAGACTTGTCAAGGAACTTG AGGCAAAGAAGATTCGCTGGGGTCAATCCATTAAGTCCTTTGAAGCTCAAGAGAAGACACTCTGTGGAGATGTTCTTCTCACGGCGGCAT TTGTGTCTTACGTCGGACCCTTCACAAGGCAGTATCGCCAGGAGCTGGTGCACTGCAAGTGGGTTCCCTTTCTTCAACAGAAGGTTTCCA TTCCACTAACCGAAGGCCTGGACTTGATATCCATGTTGACGGATGATGCTACAATTGCCGCCTGGAATAACGAAGGACTGCCCAGTGACA GAATGTCCACCGAAAATGCCGCTATCCTAACACACTGTGAGCGCTGGCCTCTGGTGATAGATCCCCAGCAACAGGGAATTAAGTGGATCA AGAATAAGTATGGAATGGACCTGAAAGTCACACATTTGGGCCAGAAAGGGTTTTTGAATGCCATTGAAACTGCTTTGGCCTTTGGTGATG TCATCTTAATTGAAAATCTCGAGGAAACGATAGATCCAGTCCTGGATCCACTACTTGGCAGGAACACAATTAAAAAAGGAAAGTATATCA GGATTGGAGATAAAGAATGTGAATTTAACAAGAACTTTCGCCTTATCCTTCACACAAAATTGGCAAATCCTCACTATAAGCCGGAATTAC AAGCTCAGACAACTCTCCTCAATTTCACAGTCACAGAAGATGGTCTAGAAGCCCAGCTGCTGGCAGAGGTTGTCAGTATTGAAAGGCCAG ATTTGGAGAAACTTAAGTTGGTATTGACAAAGCACCAAAATGATTTTAAAATTGAGCTCAAGTATCTGGAAGACGATCTCCTTTTGCGCC TTTCTGCGGCAGAGGGAAGCTTTCTGGATGACACCAAACTGGTAGAGAGATTGGAGGCAACAAAGACCACCGTGGCAGAGATAGAGCACA AGGTGATTGAAGCCAAAGAAAATGAAAGAAAAATCAACGAGGCCCGAGAATGTTACAGACCAGTGGCAGCAAGAGCATCTCTTCTTTATT TTGTTATTAATGACCTCCAAAAAATCAACCCCCTCTACCAATTCTCTTTGAAGGCTTTTAACGTGCTGTTCCACAGAGCGATCGAGCAGG CTGACAAGGTGGAAGACATGCAGGGACGCATCTCTATCCTGATGGAGAGCATCACCCATGCTGTCTTCCTCTACACCAGCCAGGCGCTGT TTGAGAAGGACAAGCTCACCTTCCTGTCCCAGATGGCTTTTCAGATTTTGTTGAGAAAGAAAGAGATAGACCCTCTTGAATTGGATTTCC TGCTTCGATTCACAGTTGAACACACTCATCTGAGTCCCGTTGACTTCCTAACTTCTCAGTCATGGAGTGCTATCAAGGCAATTGCCGTCA TGGAAGAATTTCGAGGCATAGACCGAGATGTGGAAGGATCTGCCAAGCAGTGGAGGAAGTGGGTAGAATCCGAGTGTCCAGAAAAAGAAA AATTACCTCAAGAATGGAAGAAGAAAAGTTTAATACAGAAGCTGATTCTTCTGAGAGCAATGCGCCCTGACAGAATGACGTATGCTCTCA GAAATTTTGTAGAGGAAAAACTGGGTGCGAAGTATGTGGAGAGGACCAGATTGGACTTAGTTAAAGCATTCGAAGAAAGCAGCCCAGCCA CCCCCATATTCTTCATCCTGTCTCCGGGGGTAGATGCCCTTAAAGACCTGGAGATTCTTGGCAAAAGACTTGGCTTTACAATTGACTCTG GAAAATTCCACAATGTGTCTTTAGGACAAGGTCAGGAGACGGTGGCAGAAGTGGCCCTGGAGAAAGCTTCCAAAGGAGGACACTGGGTCA TCCTCCAAAATGTTCATTTGGTAGCCAAGTGGCTAGGAACCTTGGAGAAGCTCCTTGAAAGATTCAGCCAAGGAAGCCACAGAGATTACA GGGTTTTCATGAGTGCTGAGTCTGCACCTACACCAGATGAGCATATCATCCCTCAAGGACTCCTGGAAAATTCCATTAAGATCACTAATG AACCCCCAACAGGGATGCTGGCCAATTTGCATGCCGCCCTGTACAACTTTGATCAGGATACACTTGAAATATGCTCCAAGGAGCAGGAGT TTAAAAGCATCCTTTTTTCTCTCTGCTACTTCCACGCCTGTGTTGCTGGGAGACTGAGGTTTGGCCCCCAGGGCTGGAGCCGAAGCTATC CTTTTAATCCTGGAGACCTCACCATTTGTGCCAGTGTCCTCTACAACTACTTAGAGGCAAACTCTAAAGTCCCATGGGAAGATCTCCGTT ATCTCTTTGGTGAGATCATGTATGGAGGCCACATCACAGATGACTGGGATCGCAAACTGTGTCGGGTGTATTTAGAAGAATTCATGAATC CATCTCTGACTGAAGATGAACTGATGCTGGCACCAGGTTTTGCTGCCCCACCCTACCTAGATTATGCAGGCTACCACCAGTACATAGAGG AGATGCTTCCTCCAGAAAGCCCGGCACTGTATGGCCTCCACCCAAATGCTGAAATAGAATTCCTGACAGTGACATCCAACACTCTCTTCA GAACTTTGCTGGAGATGCAGCCCAGGAATGCACTCAGTGGTGATGAACTGGGGCAGTCTACAGAAGAAAAGGTTAAGAATGTCTTGGATG ACATTTTGGAGAAACTTCCAGAAGAGTTCAACATGGCAGAGATAATGCAAAAAAATTCAAATAGAAGCCCATATGTTCTTGTTTGCTTCC AAGAATGTGAGAGGATGAATATTCTCATTCGGGAAATACGTATATCACTTGAACAACTGGACCTTAGTTTGAAGGGGGAATTGGCATTAT CTCCTGCTGTGGAAGCCCAGCAGTTTGCATTGAGTTATGACACGGTACCAGACACTTGGAGCAAACTGGCTTATCCTTCTACTTATGGCC TAGCCCAGTGGTTCAATGACCTCCTCCTGCGATGCCGAGAACTCGATACTTGGACACAAGACCTTACCCTTCCGGCTGTCGTGTGGCTCT CCGGCTTCTTCAACCCTCAGTCCTTCTTAACTGCAATCATGCAGACGATGGCTCGAAAAAATGAGTGGCCCCTGGATAAAACGCGCTTGA CTGCTGATGTTACCAAAAAAACAAAGGAAGATTATGGACACCCGCCAAGGGAAGGTGCATACCTCCACGGACTCTTCATGGAGGGCGCCC GCTGGGACACCCAAGCAGGAACCATTGTTGAAGCCCGTCTCAAGGAGCTGGCATGCCCTATGCCGGTCATCTTTGCAAAAGCCACCCCCG TGGACAGACAAGAAACCAAACAGACCTACGAGTGCCCTGTGTATAGAACCAAACTGAGAGGCCCCAGCTACATCTGGACCTTCAGGCTGA AGAGCGAAGAGAAGACTGCAAAATGGGTTCTGGCTGGAGTGGCTCTGCTTCTAGAAGCGTAAGGTAACACTGGCATTCCTCTAGCCTCTG CTGGAGTGCAGTGAGGATTTTCTAGCATGTTGCTGCACTGTTCCCATGCACATTATTCTAACTTTTTAGTAACTCACACGTGCATTCTTT TTTCAACGCTATCCTTAGAGTGAAAGTCAGAAAAAAATACTAGAAACTAACTCAGGGCTGAGCGTGGTGGCACACGACTGTAATCCCAGT TACTCAGGAGGTAGGAGAATCACTTGAACCTAGGAGGCAAAGGTTGCAGTGAGCCGAGGTTGCACCACTGCACTCCCTCCTGGGCAACAG AACAAGACTCCATCTCAAAAAAAAAAAAGTACATCATAAAAGTACATCATATGTGAACATGCAAAAGCAATGCAGCCGGAAAGAACGGAG ATTTTAATTTTTAACAAACAACAAATTAAATTATTAGCCCTTAAACTCTTTCAAAATATAAAAGCAGCAGGCCCCAGGTGAGTCCTGAAG GAAGAGGCTAGCACTCTGTAAGGCCTCCAGTGTCCAGTGTCTACAATGTTGATGGTCCCCTTTTGTTCAGTCAAGTTTTAATAAAAATAA |
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FusionGenePPI for PMS2_DNAH11 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| PMS2 | MLH1, EXO1, MSH3, BRCA2, PSD2, UBC, PRKDC, KPNA2, KPNB1, RUVBL1, RUVBL2, FAN1, PPP2CA, AIFM1, PIK3C2A, ATAD3A, MSH2, MSH6, PCNA, RFC2, DDB1, MCM3, SMARCA4, XPO1, COPB1, COPG1, COPG2, PSMC1, PSMC6, PSMD5, PSD3, PSMC3, PSMC2, CYLD, UBR5, NSUN2, BRIP1, MMS19, TOPBP1, CLSPN, SPRTN, NSF, LMNA, PMS2P1, BRCA1, REXO2, HIST1H2BG, ABCA2, FYN, XRCC3, CTR9, PARD6A, ZNRD1 | DNAH11 | ZDHHC17 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for PMS2_DNAH11 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for PMS2_DNAH11 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | PMS2 | C0265325 | Turcot syndrome (disorder) | 4 | CTD_human;ORPHANET;UNIPROT |
| Hgene | PMS2 | C0009405 | Hereditary Nonpolyposis Colorectal Neoplasms | 3 | CTD_human |
| Hgene | PMS2 | C0027627 | Neoplasm Metastasis | 1 | CTD_human |
| Hgene | PMS2 | C0035412 | Rhabdomyosarcoma | 1 | CTD_human;HPO |
| Hgene | PMS2 | C0038874 | Supratentorial Neoplasms | 1 | CTD_human |
| Hgene | PMS2 | C0206663 | Neuroectodermal Tumor, Primitive | 1 | CTD_human |
| Hgene | PMS2 | C0221263 | Cafe-au-Lait Spots | 1 | CTD_human;HPO |
| Tgene | DNAH11 | C0010068 | Coronary heart disease | 1 | CTD_human |
| Tgene | DNAH11 | C0043094 | Weight Gain | 1 | CTD_human |
| Tgene | DNAH11 | C0242339 | Dyslipidemias | 1 | CTD_human |
| Tgene | DNAH11 | C2678473 | CILIARY DYSKINESIA, PRIMARY, 7 (disorder) | 1 | CTD_human;UNIPROT |
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