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Fusion gene ID: 27731 |
FusionGeneSummary for PLXNA1_CHCHD6 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PLXNA1_CHCHD6 | Fusion gene ID: 27731 | Hgene | Tgene | Gene symbol | PLXNA1 | CHCHD6 | Gene ID | 5361 | 84303 |
| Gene name | plexin A1 | coiled-coil-helix-coiled-coil-helix domain containing 6 | |
| Synonyms | NOV|NOVP|PLEXIN-A1|PLXN1 | CHCM1|Mic25|PPP1R23 | |
| Cytomap | 3q21.3 | 3q21.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | plexin-A1plexin 1semaphorin receptor NOV | MICOS complex subunit MIC25coiled coil helix cristae morphology 1coiled-coil-helix cristae morphology protein 1coiled-coil-helix-coiled-coil-helix domain-containing protein 6, mitochondrialprotein phosphatase 1, regulatory subunit 23 | |
| Modification date | 20180523 | 20180522 | |
| UniProtAcc | Q9UIW2 | Q9BRQ6 | |
| Ensembl transtripts involved in fusion gene | ENST00000393409, ENST00000251772, ENST00000505278, | ENST00000290913, ENST00000508789, ENST00000515867, | |
| Fusion gene scores | * DoF score | 4 X 3 X 4=48 | 5 X 6 X 6=180 |
| # samples | 6 | 6 | |
| ** MAII score | log2(6/48*10)=0.321928094887362 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(6/180*10)=-1.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: PLXNA1 [Title/Abstract] AND CHCHD6 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | CHCHD6 | GO:0006974 | cellular response to DNA damage stimulus | 22228767 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | BLCA | TCGA-CF-A1HS-01A | PLXNA1 | chr3 | 126708630 | + | CHCHD6 | chr3 | 126633523 | + |
| TCGA | RV | PRAD | TCGA-HC-8265-01A | PLXNA1 | chr3 | 126710409 | + | CHCHD6 | chr3 | 126445921 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000393409 | ENST00000290913 | PLXNA1 | chr3 | 126708630 | + | CHCHD6 | chr3 | 126633523 | + |
| In-frame | ENST00000393409 | ENST00000508789 | PLXNA1 | chr3 | 126708630 | + | CHCHD6 | chr3 | 126633523 | + |
| 5CDS-3UTR | ENST00000393409 | ENST00000515867 | PLXNA1 | chr3 | 126708630 | + | CHCHD6 | chr3 | 126633523 | + |
| In-frame | ENST00000251772 | ENST00000290913 | PLXNA1 | chr3 | 126708630 | + | CHCHD6 | chr3 | 126633523 | + |
| In-frame | ENST00000251772 | ENST00000508789 | PLXNA1 | chr3 | 126708630 | + | CHCHD6 | chr3 | 126633523 | + |
| 5CDS-3UTR | ENST00000251772 | ENST00000515867 | PLXNA1 | chr3 | 126708630 | + | CHCHD6 | chr3 | 126633523 | + |
| intron-3CDS | ENST00000505278 | ENST00000290913 | PLXNA1 | chr3 | 126708630 | + | CHCHD6 | chr3 | 126633523 | + |
| intron-3CDS | ENST00000505278 | ENST00000508789 | PLXNA1 | chr3 | 126708630 | + | CHCHD6 | chr3 | 126633523 | + |
| intron-3UTR | ENST00000505278 | ENST00000515867 | PLXNA1 | chr3 | 126708630 | + | CHCHD6 | chr3 | 126633523 | + |
| In-frame | ENST00000393409 | ENST00000290913 | PLXNA1 | chr3 | 126710409 | + | CHCHD6 | chr3 | 126445921 | + |
| In-frame | ENST00000393409 | ENST00000508789 | PLXNA1 | chr3 | 126710409 | + | CHCHD6 | chr3 | 126445921 | + |
| 5CDS-intron | ENST00000393409 | ENST00000515867 | PLXNA1 | chr3 | 126710409 | + | CHCHD6 | chr3 | 126445921 | + |
| In-frame | ENST00000251772 | ENST00000290913 | PLXNA1 | chr3 | 126710409 | + | CHCHD6 | chr3 | 126445921 | + |
| In-frame | ENST00000251772 | ENST00000508789 | PLXNA1 | chr3 | 126710409 | + | CHCHD6 | chr3 | 126445921 | + |
| 5CDS-intron | ENST00000251772 | ENST00000515867 | PLXNA1 | chr3 | 126710409 | + | CHCHD6 | chr3 | 126445921 | + |
| intron-3CDS | ENST00000505278 | ENST00000290913 | PLXNA1 | chr3 | 126710409 | + | CHCHD6 | chr3 | 126445921 | + |
| intron-3CDS | ENST00000505278 | ENST00000508789 | PLXNA1 | chr3 | 126710409 | + | CHCHD6 | chr3 | 126445921 | + |
| intron-intron | ENST00000505278 | ENST00000515867 | PLXNA1 | chr3 | 126710409 | + | CHCHD6 | chr3 | 126445921 | + |
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FusionProtFeatures for PLXNA1_CHCHD6 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| PLXNA1 | CHCHD6 |
| Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D.Necessary for signaling by class 3 semaphorins and subsequentremodeling of the cytoskeleton. Plays a role in axon guidance,invasive growth and cell migration. Class 3 semaphorins bind to acomplex composed of a neuropilin and a plexin. The plexinmodulates the affinity of the complex for specific semaphorins,and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm (By similarity).{ECO:0000250}. | Component of the MICOS complex, a large protein complexof the mitochondrial inner membrane that plays crucial roles inthe maintenance of crista junctions, inner membrane architecture,and formation of contact sites to the outer membrane.{ECO:0000269|PubMed:22228767}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >CHCHD6 | chr3:126710409 | chr3:126445921 | ENST00000290913 | + | 0 | 8 | 129_176 | 29 | 236 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >CHCHD6 | chr3:126708630 | chr3:126633523 | ENST00000290913 | + | 4 | 8 | 194_235 | 165 | 236 | Domain | CHCH |
| Tgene | >CHCHD6 | chr3:126710409 | chr3:126445921 | ENST00000290913 | + | 0 | 8 | 194_235 | 29 | 236 | Domain | CHCH |
| Tgene | >CHCHD6 | chr3:126708630 | chr3:126633523 | ENST00000290913 | + | 4 | 8 | 197_207 | 165 | 236 | Motif | Cx9C motif 1 |
| Tgene | >CHCHD6 | chr3:126708630 | chr3:126633523 | ENST00000290913 | + | 4 | 8 | 218_228 | 165 | 236 | Motif | Cx9C motif 2 |
| Tgene | >CHCHD6 | chr3:126710409 | chr3:126445921 | ENST00000290913 | + | 0 | 8 | 197_207 | 29 | 236 | Motif | Cx9C motif 1 |
| Tgene | >CHCHD6 | chr3:126710409 | chr3:126445921 | ENST00000290913 | + | 0 | 8 | 218_228 | 29 | 236 | Motif | Cx9C motif 2 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >PLXNA1 | chr3:126708630 | chr3:126633523 | ENST00000393409 | + | 1 | 31 | 1264_1317 | 398 | 1897 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >PLXNA1 | chr3:126710409 | chr3:126445921 | ENST00000393409 | + | 2 | 31 | 1264_1317 | 459 | 1897 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >PLXNA1 | chr3:126708630 | chr3:126633523 | ENST00000393409 | + | 1 | 31 | 1048_1147 | 398 | 1897 | Domain | Note=IPT/TIG 3 |
| Hgene | >PLXNA1 | chr3:126708630 | chr3:126633523 | ENST00000393409 | + | 1 | 31 | 1150_1236 | 398 | 1897 | Domain | Note=IPT/TIG 4 |
| Hgene | >PLXNA1 | chr3:126708630 | chr3:126633523 | ENST00000393409 | + | 1 | 31 | 27_512 | 398 | 1897 | Domain | Sema |
| Hgene | >PLXNA1 | chr3:126708630 | chr3:126633523 | ENST00000393409 | + | 1 | 31 | 864_959 | 398 | 1897 | Domain | Note=IPT/TIG 1 |
| Hgene | >PLXNA1 | chr3:126708630 | chr3:126633523 | ENST00000393409 | + | 1 | 31 | 961_1045 | 398 | 1897 | Domain | Note=IPT/TIG 2 |
| Hgene | >PLXNA1 | chr3:126710409 | chr3:126445921 | ENST00000393409 | + | 2 | 31 | 1048_1147 | 459 | 1897 | Domain | Note=IPT/TIG 3 |
| Hgene | >PLXNA1 | chr3:126710409 | chr3:126445921 | ENST00000393409 | + | 2 | 31 | 1150_1236 | 459 | 1897 | Domain | Note=IPT/TIG 4 |
| Hgene | >PLXNA1 | chr3:126710409 | chr3:126445921 | ENST00000393409 | + | 2 | 31 | 27_512 | 459 | 1897 | Domain | Sema |
| Hgene | >PLXNA1 | chr3:126710409 | chr3:126445921 | ENST00000393409 | + | 2 | 31 | 864_959 | 459 | 1897 | Domain | Note=IPT/TIG 1 |
| Hgene | >PLXNA1 | chr3:126710409 | chr3:126445921 | ENST00000393409 | + | 2 | 31 | 961_1045 | 459 | 1897 | Domain | Note=IPT/TIG 2 |
| Hgene | >PLXNA1 | chr3:126708630 | chr3:126633523 | ENST00000393409 | + | 1 | 31 | 1266_1896 | 398 | 1897 | Topological domain | Cytoplasmic |
| Hgene | >PLXNA1 | chr3:126708630 | chr3:126633523 | ENST00000393409 | + | 1 | 31 | 27_1244 | 398 | 1897 | Topological domain | Extracellular |
| Hgene | >PLXNA1 | chr3:126710409 | chr3:126445921 | ENST00000393409 | + | 2 | 31 | 1266_1896 | 459 | 1897 | Topological domain | Cytoplasmic |
| Hgene | >PLXNA1 | chr3:126710409 | chr3:126445921 | ENST00000393409 | + | 2 | 31 | 27_1244 | 459 | 1897 | Topological domain | Extracellular |
| Hgene | >PLXNA1 | chr3:126708630 | chr3:126633523 | ENST00000393409 | + | 1 | 31 | 1245_1265 | 398 | 1897 | Transmembrane | Helical |
| Hgene | >PLXNA1 | chr3:126710409 | chr3:126445921 | ENST00000393409 | + | 2 | 31 | 1245_1265 | 459 | 1897 | Transmembrane | Helical |
| Tgene | CHCHD6 | chr3:126708630 | chr3:126633523 | ENST00000290913 | + | 4 | 8 | 129_176 | 165 | 236 | Coiled coil | Ontology_term=ECO:0000255 |
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FusionGeneSequence for PLXNA1_CHCHD6 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_PLXNA1_ENST00000393409_chr3_126710409_+_CHCHD6_ENST00000290913_chr3_126445921_+_666aa MPLPPRSLQVLLLLLLLLLLLPGMWAEAGLPRAGGGSQPPFRTFSASDWGLTHLVVHEQTGEVYVGAVNRIYKLSGNLTLLRAHVTGPVE DNEKCYPPPSVQSCPHGLGSTDNVNKLLLLDYAANRLLACGSASQGICQFLRLDDLFKLGEPHHRKEHYLSSVQEAGSMAGVLIAGPPGQ GQAKLFVGTPIDGKSEYFPTLSSRRLMANEEDADMFGFVYQDEFVSSQLKIPSDTLSKFPAFDIYYVYSFRSEQFVYYLTLQLDTQLTSP DAAGEHFFTSKIVRLCVDDPKFYSYVEFPIGCEQAGVEYRLVQDAYLSRPGRALAHQLGLAEDEDVLFTVFAQGQKNRVKPPKESALCLF TLRAIKEKIKERIQSCYRGEGKLSLPWLLNKELGCINSPLQIDDDFCGQDFNQPLGGTVTIEGTPLFVDKDDGLTAVAAYDYRGRTVVFA GTRSGRIRKLSENVVNRMKEPSSPPPAPTSSTFGLQDGNLRAPHKESTLPRSGSSGGQQPSGMKEGVKRYEQEHAAIQDKLFQVAKRERE AATKHSKASLPTGEGSISHEEQKSVRLARELESREAELRRRDTFYKEQLERIERKNAEMYKLSSEQFHEAASKMESTIKPRRVEPVCSGL >In-frame_PLXNA1_ENST00000393409_chr3_126710409_+_CHCHD6_ENST00000508789_chr3_126445921_+_687aa MPLPPRSLQVLLLLLLLLLLLPGMWAEAGLPRAGGGSQPPFRTFSASDWGLTHLVVHEQTGEVYVGAVNRIYKLSGNLTLLRAHVTGPVE DNEKCYPPPSVQSCPHGLGSTDNVNKLLLLDYAANRLLACGSASQGICQFLRLDDLFKLGEPHHRKEHYLSSVQEAGSMAGVLIAGPPGQ GQAKLFVGTPIDGKSEYFPTLSSRRLMANEEDADMFGFVYQDEFVSSQLKIPSDTLSKFPAFDIYYVYSFRSEQFVYYLTLQLDTQLTSP DAAGEHFFTSKIVRLCVDDPKFYSYVEFPIGCEQAGVEYRLVQDAYLSRPGRALAHQLGLAEDEDVLFTVFAQGQKNRVKPPKESALCLF TLRAIKEKIKERIQSCYRGEGKLSLPWLLNKELGCINSPLQIDDDFCGQDFNQPLGGTVTIEGTPLFVDKDDGLTAVAAYDYRGRTVVFA GTRSGRIRKLSENVVNRMKEPSSPPPAPTSSTFGLQDGNLRAPHKESTLPRSGSSGGQQPSGMKEGVKRYEQEHAAIQDKLFQVAKRERE AATKHSKASLPTGEGSISHEEQKSVRLQARELESREAELRRRDTFYKEQLERIERKNAEMYKLSSEQFHEAASKMESTIKPRRVEPVCSG >In-frame_PLXNA1_ENST00000251772_chr3_126710409_+_CHCHD6_ENST00000290913_chr3_126445921_+_643aa MWAEAGLPRAGGGSQPPFRTFSASDWGLTHLVVHEQTGEVYVGAVNRIYKLSGNLTLLRAHVTGPVEDNEKCYPPPSVQSCPHGLGSTDN VNKLLLLDYAANRLLACGSASQGICQFLRLDDLFKLGEPHHRKEHYLSSVQEAGSMAGVLIAGPPGQGQAKLFVGTPIDGKSEYFPTLSS RRLMANEEDADMFGFVYQDEFVSSQLKIPSDTLSKFPAFDIYYVYSFRSEQFVYYLTLQLDTQLTSPDAAGEHFFTSKIVRLCVDDPKFY SYVEFPIGCEQAGVEYRLVQDAYLSRPGRALAHQLGLAEDEDVLFTVFAQGQKNRVKPPKESALCLFTLRAIKEKIKERIQSCYRGEGKL SLPWLLNKELGCINSPLQIDDDFCGQDFNQPLGGTVTIEGTPLFVDKDDGLTAVAAYDYRGRTVVFAGTRSGRIRKLSENVVNRMKEPSS PPPAPTSSTFGLQDGNLRAPHKESTLPRSGSSGGQQPSGMKEGVKRYEQEHAAIQDKLFQVAKREREAATKHSKASLPTGEGSISHEEQK SVRLARELESREAELRRRDTFYKEQLERIERKNAEMYKLSSEQFHEAASKMESTIKPRRVEPVCSGLQAQILHCYRDRPHEVLLCSDLVK >In-frame_PLXNA1_ENST00000251772_chr3_126710409_+_CHCHD6_ENST00000508789_chr3_126445921_+_664aa MWAEAGLPRAGGGSQPPFRTFSASDWGLTHLVVHEQTGEVYVGAVNRIYKLSGNLTLLRAHVTGPVEDNEKCYPPPSVQSCPHGLGSTDN VNKLLLLDYAANRLLACGSASQGICQFLRLDDLFKLGEPHHRKEHYLSSVQEAGSMAGVLIAGPPGQGQAKLFVGTPIDGKSEYFPTLSS RRLMANEEDADMFGFVYQDEFVSSQLKIPSDTLSKFPAFDIYYVYSFRSEQFVYYLTLQLDTQLTSPDAAGEHFFTSKIVRLCVDDPKFY SYVEFPIGCEQAGVEYRLVQDAYLSRPGRALAHQLGLAEDEDVLFTVFAQGQKNRVKPPKESALCLFTLRAIKEKIKERIQSCYRGEGKL SLPWLLNKELGCINSPLQIDDDFCGQDFNQPLGGTVTIEGTPLFVDKDDGLTAVAAYDYRGRTVVFAGTRSGRIRKLSENVVNRMKEPSS PPPAPTSSTFGLQDGNLRAPHKESTLPRSGSSGGQQPSGMKEGVKRYEQEHAAIQDKLFQVAKREREAATKHSKASLPTGEGSISHEEQK SVRLQARELESREAELRRRDTFYKEQLERIERKNAEMYKLSSEQFHEAASKMESTIKPRRVEPVCSGLQAQILHCYRDRPHEVLLCSDLV |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_PLXNA1_ENST00000393409_chr3_126710409_+_CHCHD6_ENST00000290913_chr3_126445921_+_1998nt ATGCCGCTGCCACCGCGGAGCCTGCAGGTGCTCCTGCTGCTGCTGCTGTTGCTGCTGCTGCTGCCGGGCATGTGGGCTGAGGCAGGCTTG CCCAGGGCAGGCGGGGGTTCACAGCCCCCCTTCCGCACCTTCTCGGCCAGCGACTGGGGCCTCACCCACCTAGTGGTGCATGAGCAGACA GGCGAGGTGTATGTGGGCGCAGTGAACCGCATCTATAAGCTGTCGGGGAACCTGACACTGCTGCGGGCCCACGTCACGGGCCCTGTGGAG GACAACGAGAAGTGCTACCCGCCGCCCAGCGTGCAGTCCTGCCCCCACGGCCTGGGCAGTACTGACAACGTCAACAAGCTGCTGCTGCTG GACTATGCCGCTAACCGCCTGCTGGCCTGTGGCAGCGCCTCCCAGGGCATCTGCCAGTTCCTGCGTCTGGACGATCTCTTCAAACTGGGT GAGCCACACCACCGTAAGGAGCACTACCTGTCCAGCGTGCAGGAGGCAGGCAGCATGGCGGGCGTGCTCATTGCCGGGCCACCGGGCCAG GGCCAGGCCAAGCTCTTCGTGGGCACACCCATCGATGGCAAGTCCGAGTACTTCCCCACACTGTCCAGCCGTCGGCTCATGGCCAACGAG GAGGATGCCGACATGTTCGGCTTCGTGTACCAGGATGAGTTTGTGTCATCACAGCTCAAGATCCCTTCGGACACGCTGTCCAAGTTCCCG GCCTTTGACATCTACTATGTGTACAGCTTCCGCAGCGAGCAGTTTGTCTACTACCTCACGCTGCAGCTAGACACACAGCTGACCTCGCCT GATGCCGCCGGCGAGCACTTCTTCACGTCCAAGATCGTGCGGCTCTGTGTGGACGACCCCAAATTCTACTCGTACGTTGAGTTCCCCATT GGCTGCGAGCAGGCGGGTGTGGAGTACCGCCTGGTGCAGGATGCCTACCTGAGCCGGCCCGGCCGTGCCCTGGCCCACCAGCTGGGCCTG GCTGAGGACGAGGACGTGCTGTTCACTGTGTTCGCCCAGGGCCAGAAGAACCGCGTGAAGCCACCAAAGGAGTCAGCACTGTGCCTGTTC ACGCTCAGGGCCATCAAGGAGAAGATTAAGGAGCGCATCCAGTCCTGCTACCGTGGTGAGGGCAAGCTCTCCCTGCCGTGGCTGCTCAAC AAGGAGCTGGGCTGCATCAACTCGCCCCTGCAGATCGATGACGACTTCTGCGGGCAGGACTTCAACCAGCCCCTGGGGGGCACAGTCACC ATTGAGGGGACGCCCCTGTTCGTGGACAAGGATGATGGCCTGACCGCCGTGGCTGCCTATGACTATCGGGGCCGCACTGTGGTATTCGCC GGCACGCGAAGTGGCCGCATCCGCAAGCTGTCTGAAAACGTGGTGAACCGCATGAAGGAGCCCAGCTCTCCACCCCCTGCTCCCACATCT TCTACCTTTGGCCTTCAAGATGGCAACTTGAGAGCCCCTCACAAAGAATCCACACTGCCCAGGTCGGGGAGCAGTGGTGGCCAGCAGCCC TCAGGGATGAAGGAGGGTGTCAAGAGGTATGAACAGGAGCATGCTGCTATCCAGGATAAGCTCTTCCAGGTGGCAAAGAGGGAAAGAGAG GCTGCCACCAAGCACTCCAAGGCATCCCTGCCCACGGGCGAAGGCAGCATCAGCCATGAGGAGCAGAAGTCAGTCCGGCTGGCCAGGGAG CTGGAGAGCAGAGAGGCAGAGCTAAGACGCCGTGACACCTTCTACAAGGAGCAGCTGGAGCGTATTGAGAGGAAGAATGCTGAGATGTAT AAACTGTCTTCAGAGCAATTCCATGAGGCAGCCTCAAAGATGGAGAGCACAATAAAGCCCCGCAGGGTGGAGCCCGTCTGCTCAGGGTTG CAGGCCCAGATTCTCCACTGCTACCGAGATCGCCCGCATGAGGTGCTGCTGTGCTCGGACCTGGTCAAGGCATACCAGCGCTGCGTGAGC >In-frame_PLXNA1_ENST00000393409_chr3_126710409_+_CHCHD6_ENST00000508789_chr3_126445921_+_2061nt ATGCCGCTGCCACCGCGGAGCCTGCAGGTGCTCCTGCTGCTGCTGCTGTTGCTGCTGCTGCTGCCGGGCATGTGGGCTGAGGCAGGCTTG CCCAGGGCAGGCGGGGGTTCACAGCCCCCCTTCCGCACCTTCTCGGCCAGCGACTGGGGCCTCACCCACCTAGTGGTGCATGAGCAGACA GGCGAGGTGTATGTGGGCGCAGTGAACCGCATCTATAAGCTGTCGGGGAACCTGACACTGCTGCGGGCCCACGTCACGGGCCCTGTGGAG GACAACGAGAAGTGCTACCCGCCGCCCAGCGTGCAGTCCTGCCCCCACGGCCTGGGCAGTACTGACAACGTCAACAAGCTGCTGCTGCTG GACTATGCCGCTAACCGCCTGCTGGCCTGTGGCAGCGCCTCCCAGGGCATCTGCCAGTTCCTGCGTCTGGACGATCTCTTCAAACTGGGT GAGCCACACCACCGTAAGGAGCACTACCTGTCCAGCGTGCAGGAGGCAGGCAGCATGGCGGGCGTGCTCATTGCCGGGCCACCGGGCCAG GGCCAGGCCAAGCTCTTCGTGGGCACACCCATCGATGGCAAGTCCGAGTACTTCCCCACACTGTCCAGCCGTCGGCTCATGGCCAACGAG GAGGATGCCGACATGTTCGGCTTCGTGTACCAGGATGAGTTTGTGTCATCACAGCTCAAGATCCCTTCGGACACGCTGTCCAAGTTCCCG GCCTTTGACATCTACTATGTGTACAGCTTCCGCAGCGAGCAGTTTGTCTACTACCTCACGCTGCAGCTAGACACACAGCTGACCTCGCCT GATGCCGCCGGCGAGCACTTCTTCACGTCCAAGATCGTGCGGCTCTGTGTGGACGACCCCAAATTCTACTCGTACGTTGAGTTCCCCATT GGCTGCGAGCAGGCGGGTGTGGAGTACCGCCTGGTGCAGGATGCCTACCTGAGCCGGCCCGGCCGTGCCCTGGCCCACCAGCTGGGCCTG GCTGAGGACGAGGACGTGCTGTTCACTGTGTTCGCCCAGGGCCAGAAGAACCGCGTGAAGCCACCAAAGGAGTCAGCACTGTGCCTGTTC ACGCTCAGGGCCATCAAGGAGAAGATTAAGGAGCGCATCCAGTCCTGCTACCGTGGTGAGGGCAAGCTCTCCCTGCCGTGGCTGCTCAAC AAGGAGCTGGGCTGCATCAACTCGCCCCTGCAGATCGATGACGACTTCTGCGGGCAGGACTTCAACCAGCCCCTGGGGGGCACAGTCACC ATTGAGGGGACGCCCCTGTTCGTGGACAAGGATGATGGCCTGACCGCCGTGGCTGCCTATGACTATCGGGGCCGCACTGTGGTATTCGCC GGCACGCGAAGTGGCCGCATCCGCAAGCTGTCTGAAAACGTGGTGAACCGCATGAAGGAGCCCAGCTCTCCACCCCCTGCTCCCACATCT TCTACCTTTGGCCTTCAAGATGGCAACTTGAGAGCCCCTCACAAAGAATCCACACTGCCCAGGTCGGGGAGCAGTGGTGGCCAGCAGCCC TCAGGGATGAAGGAGGGTGTCAAGAGGTATGAACAGGAGCATGCTGCTATCCAGGATAAGCTCTTCCAGGTGGCAAAGAGGGAAAGAGAG GCTGCCACCAAGCACTCCAAGGCATCCCTGCCCACGGGCGAAGGCAGCATCAGCCATGAGGAGCAGAAGTCAGTCCGGCTGCAGGCCAGG GAGCTGGAGAGCAGAGAGGCAGAGCTAAGACGCCGTGACACCTTCTACAAGGAGCAGCTGGAGCGTATTGAGAGGAAGAATGCTGAGATG TATAAACTGTCTTCAGAGCAATTCCATGAGGCAGCCTCAAAGATGGAGAGCACAATAAAGCCCCGCAGGGTGGAGCCCGTCTGCTCAGGG TTGCAGGCCCAGATTCTCCACTGCTACCGAGATCGCCCGCATGAGGTGCTGCTGTGCTCGGACCTGGTCAAGGCATACCAGCGCTGCGTG >In-frame_PLXNA1_ENST00000251772_chr3_126710409_+_CHCHD6_ENST00000290913_chr3_126445921_+_1929nt ATGTGGGCTGAGGCAGGCTTGCCCAGGGCAGGCGGGGGTTCACAGCCCCCCTTCCGCACCTTCTCGGCCAGCGACTGGGGCCTCACCCAC CTAGTGGTGCATGAGCAGACAGGCGAGGTGTATGTGGGCGCAGTGAACCGCATCTATAAGCTGTCGGGGAACCTGACACTGCTGCGGGCC CACGTCACGGGCCCTGTGGAGGACAACGAGAAGTGCTACCCGCCGCCCAGCGTGCAGTCCTGCCCCCACGGCCTGGGCAGTACTGACAAC GTCAACAAGCTGCTGCTGCTGGACTATGCCGCTAACCGCCTGCTGGCCTGTGGCAGCGCCTCCCAGGGCATCTGCCAGTTCCTGCGTCTG GACGATCTCTTCAAACTGGGTGAGCCACACCACCGTAAGGAGCACTACCTGTCCAGCGTGCAGGAGGCAGGCAGCATGGCGGGCGTGCTC ATTGCCGGGCCACCGGGCCAGGGCCAGGCCAAGCTCTTCGTGGGCACACCCATCGATGGCAAGTCCGAGTACTTCCCCACACTGTCCAGC CGTCGGCTCATGGCCAACGAGGAGGATGCCGACATGTTCGGCTTCGTGTACCAGGATGAGTTTGTGTCATCACAGCTCAAGATCCCTTCG GACACGCTGTCCAAGTTCCCGGCCTTTGACATCTACTATGTGTACAGCTTCCGCAGCGAGCAGTTTGTCTACTACCTCACGCTGCAGCTA GACACACAGCTGACCTCGCCTGATGCCGCCGGCGAGCACTTCTTCACGTCCAAGATCGTGCGGCTCTGTGTGGACGACCCCAAATTCTAC TCGTACGTTGAGTTCCCCATTGGCTGCGAGCAGGCGGGTGTGGAGTACCGCCTGGTGCAGGATGCCTACCTGAGCCGGCCCGGCCGTGCC CTGGCCCACCAGCTGGGCCTGGCTGAGGACGAGGACGTGCTGTTCACTGTGTTCGCCCAGGGCCAGAAGAACCGCGTGAAGCCACCAAAG GAGTCAGCACTGTGCCTGTTCACGCTCAGGGCCATCAAGGAGAAGATTAAGGAGCGCATCCAGTCCTGCTACCGTGGTGAGGGCAAGCTC TCCCTGCCGTGGCTGCTCAACAAGGAGCTGGGCTGCATCAACTCGCCCCTGCAGATCGATGACGACTTCTGCGGGCAGGACTTCAACCAG CCCCTGGGGGGCACAGTCACCATTGAGGGGACGCCCCTGTTCGTGGACAAGGATGATGGCCTGACCGCCGTGGCTGCCTATGACTATCGG GGCCGCACTGTGGTATTCGCCGGCACGCGAAGTGGCCGCATCCGCAAGCTGTCTGAAAACGTGGTGAACCGCATGAAGGAGCCCAGCTCT CCACCCCCTGCTCCCACATCTTCTACCTTTGGCCTTCAAGATGGCAACTTGAGAGCCCCTCACAAAGAATCCACACTGCCCAGGTCGGGG AGCAGTGGTGGCCAGCAGCCCTCAGGGATGAAGGAGGGTGTCAAGAGGTATGAACAGGAGCATGCTGCTATCCAGGATAAGCTCTTCCAG GTGGCAAAGAGGGAAAGAGAGGCTGCCACCAAGCACTCCAAGGCATCCCTGCCCACGGGCGAAGGCAGCATCAGCCATGAGGAGCAGAAG TCAGTCCGGCTGGCCAGGGAGCTGGAGAGCAGAGAGGCAGAGCTAAGACGCCGTGACACCTTCTACAAGGAGCAGCTGGAGCGTATTGAG AGGAAGAATGCTGAGATGTATAAACTGTCTTCAGAGCAATTCCATGAGGCAGCCTCAAAGATGGAGAGCACAATAAAGCCCCGCAGGGTG GAGCCCGTCTGCTCAGGGTTGCAGGCCCAGATTCTCCACTGCTACCGAGATCGCCCGCATGAGGTGCTGCTGTGCTCGGACCTGGTCAAG >In-frame_PLXNA1_ENST00000251772_chr3_126710409_+_CHCHD6_ENST00000508789_chr3_126445921_+_1992nt ATGTGGGCTGAGGCAGGCTTGCCCAGGGCAGGCGGGGGTTCACAGCCCCCCTTCCGCACCTTCTCGGCCAGCGACTGGGGCCTCACCCAC CTAGTGGTGCATGAGCAGACAGGCGAGGTGTATGTGGGCGCAGTGAACCGCATCTATAAGCTGTCGGGGAACCTGACACTGCTGCGGGCC CACGTCACGGGCCCTGTGGAGGACAACGAGAAGTGCTACCCGCCGCCCAGCGTGCAGTCCTGCCCCCACGGCCTGGGCAGTACTGACAAC GTCAACAAGCTGCTGCTGCTGGACTATGCCGCTAACCGCCTGCTGGCCTGTGGCAGCGCCTCCCAGGGCATCTGCCAGTTCCTGCGTCTG GACGATCTCTTCAAACTGGGTGAGCCACACCACCGTAAGGAGCACTACCTGTCCAGCGTGCAGGAGGCAGGCAGCATGGCGGGCGTGCTC ATTGCCGGGCCACCGGGCCAGGGCCAGGCCAAGCTCTTCGTGGGCACACCCATCGATGGCAAGTCCGAGTACTTCCCCACACTGTCCAGC CGTCGGCTCATGGCCAACGAGGAGGATGCCGACATGTTCGGCTTCGTGTACCAGGATGAGTTTGTGTCATCACAGCTCAAGATCCCTTCG GACACGCTGTCCAAGTTCCCGGCCTTTGACATCTACTATGTGTACAGCTTCCGCAGCGAGCAGTTTGTCTACTACCTCACGCTGCAGCTA GACACACAGCTGACCTCGCCTGATGCCGCCGGCGAGCACTTCTTCACGTCCAAGATCGTGCGGCTCTGTGTGGACGACCCCAAATTCTAC TCGTACGTTGAGTTCCCCATTGGCTGCGAGCAGGCGGGTGTGGAGTACCGCCTGGTGCAGGATGCCTACCTGAGCCGGCCCGGCCGTGCC CTGGCCCACCAGCTGGGCCTGGCTGAGGACGAGGACGTGCTGTTCACTGTGTTCGCCCAGGGCCAGAAGAACCGCGTGAAGCCACCAAAG GAGTCAGCACTGTGCCTGTTCACGCTCAGGGCCATCAAGGAGAAGATTAAGGAGCGCATCCAGTCCTGCTACCGTGGTGAGGGCAAGCTC TCCCTGCCGTGGCTGCTCAACAAGGAGCTGGGCTGCATCAACTCGCCCCTGCAGATCGATGACGACTTCTGCGGGCAGGACTTCAACCAG CCCCTGGGGGGCACAGTCACCATTGAGGGGACGCCCCTGTTCGTGGACAAGGATGATGGCCTGACCGCCGTGGCTGCCTATGACTATCGG GGCCGCACTGTGGTATTCGCCGGCACGCGAAGTGGCCGCATCCGCAAGCTGTCTGAAAACGTGGTGAACCGCATGAAGGAGCCCAGCTCT CCACCCCCTGCTCCCACATCTTCTACCTTTGGCCTTCAAGATGGCAACTTGAGAGCCCCTCACAAAGAATCCACACTGCCCAGGTCGGGG AGCAGTGGTGGCCAGCAGCCCTCAGGGATGAAGGAGGGTGTCAAGAGGTATGAACAGGAGCATGCTGCTATCCAGGATAAGCTCTTCCAG GTGGCAAAGAGGGAAAGAGAGGCTGCCACCAAGCACTCCAAGGCATCCCTGCCCACGGGCGAAGGCAGCATCAGCCATGAGGAGCAGAAG TCAGTCCGGCTGCAGGCCAGGGAGCTGGAGAGCAGAGAGGCAGAGCTAAGACGCCGTGACACCTTCTACAAGGAGCAGCTGGAGCGTATT GAGAGGAAGAATGCTGAGATGTATAAACTGTCTTCAGAGCAATTCCATGAGGCAGCCTCAAAGATGGAGAGCACAATAAAGCCCCGCAGG GTGGAGCCCGTCTGCTCAGGGTTGCAGGCCCAGATTCTCCACTGCTACCGAGATCGCCCGCATGAGGTGCTGCTGTGCTCGGACCTGGTC AAGGCATACCAGCGCTGCGTGAGCGCCGCCCACAAGGTAAGGCCTTGCCTGCCTCCCAGGTTTCCAAGGGCCTTGGGAGGTAGGCGAGGT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_PLXNA1_ENST00000393409_chr3_126710409_+_CHCHD6_ENST00000290913_chr3_126445921_+_2203nt ATGCCGCTGCCACCGCGGAGCCTGCAGGTGCTCCTGCTGCTGCTGCTGTTGCTGCTGCTGCTGCCGGGCATGTGGGCTGAGGCAGGCTTG CCCAGGGCAGGCGGGGGTTCACAGCCCCCCTTCCGCACCTTCTCGGCCAGCGACTGGGGCCTCACCCACCTAGTGGTGCATGAGCAGACA GGCGAGGTGTATGTGGGCGCAGTGAACCGCATCTATAAGCTGTCGGGGAACCTGACACTGCTGCGGGCCCACGTCACGGGCCCTGTGGAG GACAACGAGAAGTGCTACCCGCCGCCCAGCGTGCAGTCCTGCCCCCACGGCCTGGGCAGTACTGACAACGTCAACAAGCTGCTGCTGCTG GACTATGCCGCTAACCGCCTGCTGGCCTGTGGCAGCGCCTCCCAGGGCATCTGCCAGTTCCTGCGTCTGGACGATCTCTTCAAACTGGGT GAGCCACACCACCGTAAGGAGCACTACCTGTCCAGCGTGCAGGAGGCAGGCAGCATGGCGGGCGTGCTCATTGCCGGGCCACCGGGCCAG GGCCAGGCCAAGCTCTTCGTGGGCACACCCATCGATGGCAAGTCCGAGTACTTCCCCACACTGTCCAGCCGTCGGCTCATGGCCAACGAG GAGGATGCCGACATGTTCGGCTTCGTGTACCAGGATGAGTTTGTGTCATCACAGCTCAAGATCCCTTCGGACACGCTGTCCAAGTTCCCG GCCTTTGACATCTACTATGTGTACAGCTTCCGCAGCGAGCAGTTTGTCTACTACCTCACGCTGCAGCTAGACACACAGCTGACCTCGCCT GATGCCGCCGGCGAGCACTTCTTCACGTCCAAGATCGTGCGGCTCTGTGTGGACGACCCCAAATTCTACTCGTACGTTGAGTTCCCCATT GGCTGCGAGCAGGCGGGTGTGGAGTACCGCCTGGTGCAGGATGCCTACCTGAGCCGGCCCGGCCGTGCCCTGGCCCACCAGCTGGGCCTG GCTGAGGACGAGGACGTGCTGTTCACTGTGTTCGCCCAGGGCCAGAAGAACCGCGTGAAGCCACCAAAGGAGTCAGCACTGTGCCTGTTC ACGCTCAGGGCCATCAAGGAGAAGATTAAGGAGCGCATCCAGTCCTGCTACCGTGGTGAGGGCAAGCTCTCCCTGCCGTGGCTGCTCAAC AAGGAGCTGGGCTGCATCAACTCGCCCCTGCAGATCGATGACGACTTCTGCGGGCAGGACTTCAACCAGCCCCTGGGGGGCACAGTCACC ATTGAGGGGACGCCCCTGTTCGTGGACAAGGATGATGGCCTGACCGCCGTGGCTGCCTATGACTATCGGGGCCGCACTGTGGTATTCGCC GGCACGCGAAGTGGCCGCATCCGCAAGCTGTCTGAAAACGTGGTGAACCGCATGAAGGAGCCCAGCTCTCCACCCCCTGCTCCCACATCT TCTACCTTTGGCCTTCAAGATGGCAACTTGAGAGCCCCTCACAAAGAATCCACACTGCCCAGGTCGGGGAGCAGTGGTGGCCAGCAGCCC TCAGGGATGAAGGAGGGTGTCAAGAGGTATGAACAGGAGCATGCTGCTATCCAGGATAAGCTCTTCCAGGTGGCAAAGAGGGAAAGAGAG GCTGCCACCAAGCACTCCAAGGCATCCCTGCCCACGGGCGAAGGCAGCATCAGCCATGAGGAGCAGAAGTCAGTCCGGCTGGCCAGGGAG CTGGAGAGCAGAGAGGCAGAGCTAAGACGCCGTGACACCTTCTACAAGGAGCAGCTGGAGCGTATTGAGAGGAAGAATGCTGAGATGTAT AAACTGTCTTCAGAGCAATTCCATGAGGCAGCCTCAAAGATGGAGAGCACAATAAAGCCCCGCAGGGTGGAGCCCGTCTGCTCAGGGTTG CAGGCCCAGATTCTCCACTGCTACCGAGATCGCCCGCATGAGGTGCTGCTGTGCTCGGACCTGGTCAAGGCATACCAGCGCTGCGTGAGC GCCGCCCACAAGGGCTGAGGAGCAGACATCATTCCCTGCCCTGGCAGTGACTTGGAGCCCTGAAGAAGGGACCAATCATGGGACCACAGC CACTGTGCCCTGCCGTTTCCTGCTGGGCCCCTGCATATGCCCCTGAGCCTGGGGCTGCCACGTGTTTAGGAAACAAAGTATGCGCTACTG >In-frame_PLXNA1_ENST00000393409_chr3_126710409_+_CHCHD6_ENST00000508789_chr3_126445921_+_2377nt ATGCCGCTGCCACCGCGGAGCCTGCAGGTGCTCCTGCTGCTGCTGCTGTTGCTGCTGCTGCTGCCGGGCATGTGGGCTGAGGCAGGCTTG CCCAGGGCAGGCGGGGGTTCACAGCCCCCCTTCCGCACCTTCTCGGCCAGCGACTGGGGCCTCACCCACCTAGTGGTGCATGAGCAGACA GGCGAGGTGTATGTGGGCGCAGTGAACCGCATCTATAAGCTGTCGGGGAACCTGACACTGCTGCGGGCCCACGTCACGGGCCCTGTGGAG GACAACGAGAAGTGCTACCCGCCGCCCAGCGTGCAGTCCTGCCCCCACGGCCTGGGCAGTACTGACAACGTCAACAAGCTGCTGCTGCTG GACTATGCCGCTAACCGCCTGCTGGCCTGTGGCAGCGCCTCCCAGGGCATCTGCCAGTTCCTGCGTCTGGACGATCTCTTCAAACTGGGT GAGCCACACCACCGTAAGGAGCACTACCTGTCCAGCGTGCAGGAGGCAGGCAGCATGGCGGGCGTGCTCATTGCCGGGCCACCGGGCCAG GGCCAGGCCAAGCTCTTCGTGGGCACACCCATCGATGGCAAGTCCGAGTACTTCCCCACACTGTCCAGCCGTCGGCTCATGGCCAACGAG GAGGATGCCGACATGTTCGGCTTCGTGTACCAGGATGAGTTTGTGTCATCACAGCTCAAGATCCCTTCGGACACGCTGTCCAAGTTCCCG GCCTTTGACATCTACTATGTGTACAGCTTCCGCAGCGAGCAGTTTGTCTACTACCTCACGCTGCAGCTAGACACACAGCTGACCTCGCCT GATGCCGCCGGCGAGCACTTCTTCACGTCCAAGATCGTGCGGCTCTGTGTGGACGACCCCAAATTCTACTCGTACGTTGAGTTCCCCATT GGCTGCGAGCAGGCGGGTGTGGAGTACCGCCTGGTGCAGGATGCCTACCTGAGCCGGCCCGGCCGTGCCCTGGCCCACCAGCTGGGCCTG GCTGAGGACGAGGACGTGCTGTTCACTGTGTTCGCCCAGGGCCAGAAGAACCGCGTGAAGCCACCAAAGGAGTCAGCACTGTGCCTGTTC ACGCTCAGGGCCATCAAGGAGAAGATTAAGGAGCGCATCCAGTCCTGCTACCGTGGTGAGGGCAAGCTCTCCCTGCCGTGGCTGCTCAAC AAGGAGCTGGGCTGCATCAACTCGCCCCTGCAGATCGATGACGACTTCTGCGGGCAGGACTTCAACCAGCCCCTGGGGGGCACAGTCACC ATTGAGGGGACGCCCCTGTTCGTGGACAAGGATGATGGCCTGACCGCCGTGGCTGCCTATGACTATCGGGGCCGCACTGTGGTATTCGCC GGCACGCGAAGTGGCCGCATCCGCAAGCTGTCTGAAAACGTGGTGAACCGCATGAAGGAGCCCAGCTCTCCACCCCCTGCTCCCACATCT TCTACCTTTGGCCTTCAAGATGGCAACTTGAGAGCCCCTCACAAAGAATCCACACTGCCCAGGTCGGGGAGCAGTGGTGGCCAGCAGCCC TCAGGGATGAAGGAGGGTGTCAAGAGGTATGAACAGGAGCATGCTGCTATCCAGGATAAGCTCTTCCAGGTGGCAAAGAGGGAAAGAGAG GCTGCCACCAAGCACTCCAAGGCATCCCTGCCCACGGGCGAAGGCAGCATCAGCCATGAGGAGCAGAAGTCAGTCCGGCTGCAGGCCAGG GAGCTGGAGAGCAGAGAGGCAGAGCTAAGACGCCGTGACACCTTCTACAAGGAGCAGCTGGAGCGTATTGAGAGGAAGAATGCTGAGATG TATAAACTGTCTTCAGAGCAATTCCATGAGGCAGCCTCAAAGATGGAGAGCACAATAAAGCCCCGCAGGGTGGAGCCCGTCTGCTCAGGG TTGCAGGCCCAGATTCTCCACTGCTACCGAGATCGCCCGCATGAGGTGCTGCTGTGCTCGGACCTGGTCAAGGCATACCAGCGCTGCGTG AGCGCCGCCCACAAGGTAAGGCCTTGCCTGCCTCCCAGGTTTCCAAGGGCCTTGGGAGGTAGGCGAGGTACCTCTATCTAGCATTGGAGA TCTCTGCCTGCCTTTTCCTGTTAGAATCAGATGCTCCACTTGGAGGTCTCTGCATTTGCCAAGGGAGGGATTCTTCGCTTTCCTCAGTCA CCTGCACACTCTCCTGGCTGCTTCCAGGAGCGCCTTGGACATCTGGCCCCAGGGAGATGATCCCTGTTGCGTTTGCCCTATTAGGCTGGG TGGGAGCAGGCTGGGTAAAGTCAGGCCCCACCTTCAAGGGCCGGGCCCCTTGTGGGTGCCGGGGACTTCTTAGCCCTCGGCACTTAGGGG >In-frame_PLXNA1_ENST00000251772_chr3_126710409_+_CHCHD6_ENST00000290913_chr3_126445921_+_2203nt ATGCCGCTGCCACCGCGGAGCCTGCAGGTGCTCCTGCTGCTGCTGCTGTTGCTGCTGCTGCTGCCGGGCATGTGGGCTGAGGCAGGCTTG CCCAGGGCAGGCGGGGGTTCACAGCCCCCCTTCCGCACCTTCTCGGCCAGCGACTGGGGCCTCACCCACCTAGTGGTGCATGAGCAGACA GGCGAGGTGTATGTGGGCGCAGTGAACCGCATCTATAAGCTGTCGGGGAACCTGACACTGCTGCGGGCCCACGTCACGGGCCCTGTGGAG GACAACGAGAAGTGCTACCCGCCGCCCAGCGTGCAGTCCTGCCCCCACGGCCTGGGCAGTACTGACAACGTCAACAAGCTGCTGCTGCTG GACTATGCCGCTAACCGCCTGCTGGCCTGTGGCAGCGCCTCCCAGGGCATCTGCCAGTTCCTGCGTCTGGACGATCTCTTCAAACTGGGT GAGCCACACCACCGTAAGGAGCACTACCTGTCCAGCGTGCAGGAGGCAGGCAGCATGGCGGGCGTGCTCATTGCCGGGCCACCGGGCCAG GGCCAGGCCAAGCTCTTCGTGGGCACACCCATCGATGGCAAGTCCGAGTACTTCCCCACACTGTCCAGCCGTCGGCTCATGGCCAACGAG GAGGATGCCGACATGTTCGGCTTCGTGTACCAGGATGAGTTTGTGTCATCACAGCTCAAGATCCCTTCGGACACGCTGTCCAAGTTCCCG GCCTTTGACATCTACTATGTGTACAGCTTCCGCAGCGAGCAGTTTGTCTACTACCTCACGCTGCAGCTAGACACACAGCTGACCTCGCCT GATGCCGCCGGCGAGCACTTCTTCACGTCCAAGATCGTGCGGCTCTGTGTGGACGACCCCAAATTCTACTCGTACGTTGAGTTCCCCATT GGCTGCGAGCAGGCGGGTGTGGAGTACCGCCTGGTGCAGGATGCCTACCTGAGCCGGCCCGGCCGTGCCCTGGCCCACCAGCTGGGCCTG GCTGAGGACGAGGACGTGCTGTTCACTGTGTTCGCCCAGGGCCAGAAGAACCGCGTGAAGCCACCAAAGGAGTCAGCACTGTGCCTGTTC ACGCTCAGGGCCATCAAGGAGAAGATTAAGGAGCGCATCCAGTCCTGCTACCGTGGTGAGGGCAAGCTCTCCCTGCCGTGGCTGCTCAAC AAGGAGCTGGGCTGCATCAACTCGCCCCTGCAGATCGATGACGACTTCTGCGGGCAGGACTTCAACCAGCCCCTGGGGGGCACAGTCACC ATTGAGGGGACGCCCCTGTTCGTGGACAAGGATGATGGCCTGACCGCCGTGGCTGCCTATGACTATCGGGGCCGCACTGTGGTATTCGCC GGCACGCGAAGTGGCCGCATCCGCAAGCTGTCTGAAAACGTGGTGAACCGCATGAAGGAGCCCAGCTCTCCACCCCCTGCTCCCACATCT TCTACCTTTGGCCTTCAAGATGGCAACTTGAGAGCCCCTCACAAAGAATCCACACTGCCCAGGTCGGGGAGCAGTGGTGGCCAGCAGCCC TCAGGGATGAAGGAGGGTGTCAAGAGGTATGAACAGGAGCATGCTGCTATCCAGGATAAGCTCTTCCAGGTGGCAAAGAGGGAAAGAGAG GCTGCCACCAAGCACTCCAAGGCATCCCTGCCCACGGGCGAAGGCAGCATCAGCCATGAGGAGCAGAAGTCAGTCCGGCTGGCCAGGGAG CTGGAGAGCAGAGAGGCAGAGCTAAGACGCCGTGACACCTTCTACAAGGAGCAGCTGGAGCGTATTGAGAGGAAGAATGCTGAGATGTAT AAACTGTCTTCAGAGCAATTCCATGAGGCAGCCTCAAAGATGGAGAGCACAATAAAGCCCCGCAGGGTGGAGCCCGTCTGCTCAGGGTTG CAGGCCCAGATTCTCCACTGCTACCGAGATCGCCCGCATGAGGTGCTGCTGTGCTCGGACCTGGTCAAGGCATACCAGCGCTGCGTGAGC GCCGCCCACAAGGGCTGAGGAGCAGACATCATTCCCTGCCCTGGCAGTGACTTGGAGCCCTGAAGAAGGGACCAATCATGGGACCACAGC CACTGTGCCCTGCCGTTTCCTGCTGGGCCCCTGCATATGCCCCTGAGCCTGGGGCTGCCACGTGTTTAGGAAACAAAGTATGCGCTACTG >In-frame_PLXNA1_ENST00000251772_chr3_126710409_+_CHCHD6_ENST00000508789_chr3_126445921_+_2377nt ATGCCGCTGCCACCGCGGAGCCTGCAGGTGCTCCTGCTGCTGCTGCTGTTGCTGCTGCTGCTGCCGGGCATGTGGGCTGAGGCAGGCTTG CCCAGGGCAGGCGGGGGTTCACAGCCCCCCTTCCGCACCTTCTCGGCCAGCGACTGGGGCCTCACCCACCTAGTGGTGCATGAGCAGACA GGCGAGGTGTATGTGGGCGCAGTGAACCGCATCTATAAGCTGTCGGGGAACCTGACACTGCTGCGGGCCCACGTCACGGGCCCTGTGGAG GACAACGAGAAGTGCTACCCGCCGCCCAGCGTGCAGTCCTGCCCCCACGGCCTGGGCAGTACTGACAACGTCAACAAGCTGCTGCTGCTG GACTATGCCGCTAACCGCCTGCTGGCCTGTGGCAGCGCCTCCCAGGGCATCTGCCAGTTCCTGCGTCTGGACGATCTCTTCAAACTGGGT GAGCCACACCACCGTAAGGAGCACTACCTGTCCAGCGTGCAGGAGGCAGGCAGCATGGCGGGCGTGCTCATTGCCGGGCCACCGGGCCAG GGCCAGGCCAAGCTCTTCGTGGGCACACCCATCGATGGCAAGTCCGAGTACTTCCCCACACTGTCCAGCCGTCGGCTCATGGCCAACGAG GAGGATGCCGACATGTTCGGCTTCGTGTACCAGGATGAGTTTGTGTCATCACAGCTCAAGATCCCTTCGGACACGCTGTCCAAGTTCCCG GCCTTTGACATCTACTATGTGTACAGCTTCCGCAGCGAGCAGTTTGTCTACTACCTCACGCTGCAGCTAGACACACAGCTGACCTCGCCT GATGCCGCCGGCGAGCACTTCTTCACGTCCAAGATCGTGCGGCTCTGTGTGGACGACCCCAAATTCTACTCGTACGTTGAGTTCCCCATT GGCTGCGAGCAGGCGGGTGTGGAGTACCGCCTGGTGCAGGATGCCTACCTGAGCCGGCCCGGCCGTGCCCTGGCCCACCAGCTGGGCCTG GCTGAGGACGAGGACGTGCTGTTCACTGTGTTCGCCCAGGGCCAGAAGAACCGCGTGAAGCCACCAAAGGAGTCAGCACTGTGCCTGTTC ACGCTCAGGGCCATCAAGGAGAAGATTAAGGAGCGCATCCAGTCCTGCTACCGTGGTGAGGGCAAGCTCTCCCTGCCGTGGCTGCTCAAC AAGGAGCTGGGCTGCATCAACTCGCCCCTGCAGATCGATGACGACTTCTGCGGGCAGGACTTCAACCAGCCCCTGGGGGGCACAGTCACC ATTGAGGGGACGCCCCTGTTCGTGGACAAGGATGATGGCCTGACCGCCGTGGCTGCCTATGACTATCGGGGCCGCACTGTGGTATTCGCC GGCACGCGAAGTGGCCGCATCCGCAAGCTGTCTGAAAACGTGGTGAACCGCATGAAGGAGCCCAGCTCTCCACCCCCTGCTCCCACATCT TCTACCTTTGGCCTTCAAGATGGCAACTTGAGAGCCCCTCACAAAGAATCCACACTGCCCAGGTCGGGGAGCAGTGGTGGCCAGCAGCCC TCAGGGATGAAGGAGGGTGTCAAGAGGTATGAACAGGAGCATGCTGCTATCCAGGATAAGCTCTTCCAGGTGGCAAAGAGGGAAAGAGAG GCTGCCACCAAGCACTCCAAGGCATCCCTGCCCACGGGCGAAGGCAGCATCAGCCATGAGGAGCAGAAGTCAGTCCGGCTGCAGGCCAGG GAGCTGGAGAGCAGAGAGGCAGAGCTAAGACGCCGTGACACCTTCTACAAGGAGCAGCTGGAGCGTATTGAGAGGAAGAATGCTGAGATG TATAAACTGTCTTCAGAGCAATTCCATGAGGCAGCCTCAAAGATGGAGAGCACAATAAAGCCCCGCAGGGTGGAGCCCGTCTGCTCAGGG TTGCAGGCCCAGATTCTCCACTGCTACCGAGATCGCCCGCATGAGGTGCTGCTGTGCTCGGACCTGGTCAAGGCATACCAGCGCTGCGTG AGCGCCGCCCACAAGGTAAGGCCTTGCCTGCCTCCCAGGTTTCCAAGGGCCTTGGGAGGTAGGCGAGGTACCTCTATCTAGCATTGGAGA TCTCTGCCTGCCTTTTCCTGTTAGAATCAGATGCTCCACTTGGAGGTCTCTGCATTTGCCAAGGGAGGGATTCTTCGCTTTCCTCAGTCA CCTGCACACTCTCCTGGCTGCTTCCAGGAGCGCCTTGGACATCTGGCCCCAGGGAGATGATCCCTGTTGCGTTTGCCCTATTAGGCTGGG TGGGAGCAGGCTGGGTAAAGTCAGGCCCCACCTTCAAGGGCCGGGCCCCTTGTGGGTGCCGGGGACTTCTTAGCCCTCGGCACTTAGGGG |
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FusionGenePPI for PLXNA1_CHCHD6 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| PLXNA1 | AKT1, PLXNA1, KDR, RHOD, FBXO6, PDIA3, HLA-DRA, TAZ, SUSD4, LGALS9, TMEM25, CANT1, PTCH1, PTPRK, NRP1, GAN, OS9, FAM19A4, ST8SIA4, DEFA5, SCGB1D1, DEFA1, MGAT4C | CHCHD6 | UBC, APP, ERLIN1, TMED4, SLC25A12, PTPLAD1, NPM1, CLEC5A, CHCHD2, NDUFA8, RAB7A, VAPA, MTX2, GOLT1B, MMGT1, C19orf70, APOOL, SLC22A16, CD244, INVS |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for PLXNA1_CHCHD6 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for PLXNA1_CHCHD6 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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