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Fusion gene ID: 27666 |
FusionGeneSummary for PLEKHM2_ECE1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PLEKHM2_ECE1 | Fusion gene ID: 27666 | Hgene | Tgene | Gene symbol | PLEKHM2 | ECE1 | Gene ID | 23207 | 1889 |
| Gene name | pleckstrin homology and RUN domain containing M2 | endothelin converting enzyme 1 | |
| Synonyms | SKIP | ECE | |
| Cytomap | 1p36.21 | 1p36.12 | |
| Type of gene | protein-coding | protein-coding | |
| Description | pleckstrin homology domain-containing family M member 2PH domain-containing family M member 2SifA (Salmonella-induced filaments A) and kinesin-interacting proteinnovel RUN and PH domain-containing proteinpleckstrin homology domain containing, family M | endothelin-converting enzyme 1ECE-1 | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q8IWE5 | P42892 | |
| Ensembl transtripts involved in fusion gene | ENST00000375799, ENST00000375793, ENST00000477849, | ENST00000415912, ENST00000357071, ENST00000374893, ENST00000436918, ENST00000264205, ENST00000528294, | |
| Fusion gene scores | * DoF score | 4 X 3 X 4=48 | 8 X 10 X 6=480 |
| # samples | 4 | 13 | |
| ** MAII score | log2(4/48*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(13/480*10)=-1.88452278258006 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: PLEKHM2 [Title/Abstract] AND ECE1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | PLEKHM2 | GO:1903527 | positive regulation of membrane tubulation | 18996344 |
| Tgene | ECE1 | GO:0010814 | substance P catabolic process | 18039931 |
| Tgene | ECE1 | GO:0010815 | bradykinin catabolic process | 18039931 |
| Tgene | ECE1 | GO:0010816 | calcitonin catabolic process | 18039931 |
| Tgene | ECE1 | GO:0016485 | protein processing | 7805846 |
| Tgene | ECE1 | GO:0016486 | peptide hormone processing | 7864876 |
| Tgene | ECE1 | GO:0034959 | endothelin maturation | 7805846 |
| Tgene | ECE1 | GO:0042447 | hormone catabolic process | 7864876 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | SARC | TCGA-DX-A8BV-01A | PLEKHM2 | chr1 | 16045120 | + | ECE1 | chr1 | 21573856 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000375799 | ENST00000415912 | PLEKHM2 | chr1 | 16045120 | + | ECE1 | chr1 | 21573856 | - |
| In-frame | ENST00000375799 | ENST00000357071 | PLEKHM2 | chr1 | 16045120 | + | ECE1 | chr1 | 21573856 | - |
| In-frame | ENST00000375799 | ENST00000374893 | PLEKHM2 | chr1 | 16045120 | + | ECE1 | chr1 | 21573856 | - |
| In-frame | ENST00000375799 | ENST00000436918 | PLEKHM2 | chr1 | 16045120 | + | ECE1 | chr1 | 21573856 | - |
| In-frame | ENST00000375799 | ENST00000264205 | PLEKHM2 | chr1 | 16045120 | + | ECE1 | chr1 | 21573856 | - |
| 5CDS-5UTR | ENST00000375799 | ENST00000528294 | PLEKHM2 | chr1 | 16045120 | + | ECE1 | chr1 | 21573856 | - |
| In-frame | ENST00000375793 | ENST00000415912 | PLEKHM2 | chr1 | 16045120 | + | ECE1 | chr1 | 21573856 | - |
| In-frame | ENST00000375793 | ENST00000357071 | PLEKHM2 | chr1 | 16045120 | + | ECE1 | chr1 | 21573856 | - |
| In-frame | ENST00000375793 | ENST00000374893 | PLEKHM2 | chr1 | 16045120 | + | ECE1 | chr1 | 21573856 | - |
| In-frame | ENST00000375793 | ENST00000436918 | PLEKHM2 | chr1 | 16045120 | + | ECE1 | chr1 | 21573856 | - |
| In-frame | ENST00000375793 | ENST00000264205 | PLEKHM2 | chr1 | 16045120 | + | ECE1 | chr1 | 21573856 | - |
| 5CDS-5UTR | ENST00000375793 | ENST00000528294 | PLEKHM2 | chr1 | 16045120 | + | ECE1 | chr1 | 21573856 | - |
| intron-3CDS | ENST00000477849 | ENST00000415912 | PLEKHM2 | chr1 | 16045120 | + | ECE1 | chr1 | 21573856 | - |
| intron-3CDS | ENST00000477849 | ENST00000357071 | PLEKHM2 | chr1 | 16045120 | + | ECE1 | chr1 | 21573856 | - |
| intron-3CDS | ENST00000477849 | ENST00000374893 | PLEKHM2 | chr1 | 16045120 | + | ECE1 | chr1 | 21573856 | - |
| intron-3CDS | ENST00000477849 | ENST00000436918 | PLEKHM2 | chr1 | 16045120 | + | ECE1 | chr1 | 21573856 | - |
| intron-3CDS | ENST00000477849 | ENST00000264205 | PLEKHM2 | chr1 | 16045120 | + | ECE1 | chr1 | 21573856 | - |
| intron-5UTR | ENST00000477849 | ENST00000528294 | PLEKHM2 | chr1 | 16045120 | + | ECE1 | chr1 | 21573856 | - |
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FusionProtFeatures for PLEKHM2_ECE1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| PLEKHM2 | ECE1 |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | PLEKHM2 | chr1:16045120 | chr1:21573856 | ENST00000375799 | + | 5 | 20 | 36_158 | 155 | 1020 | Domain | RUN |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >PLEKHM2 | chr1:16045120 | chr1:21573856 | ENST00000375799 | + | 5 | 20 | 317_320 | 155 | 1020 | Compositional bias | Note=Poly-Lys |
| Hgene | >PLEKHM2 | chr1:16045120 | chr1:21573856 | ENST00000375799 | + | 5 | 20 | 323_326 | 155 | 1020 | Compositional bias | Note=Poly-Lys |
| Hgene | >PLEKHM2 | chr1:16045120 | chr1:21573856 | ENST00000375799 | + | 5 | 20 | 506_511 | 155 | 1020 | Compositional bias | Note=Poly-Gly |
| Hgene | >PLEKHM2 | chr1:16045120 | chr1:21573856 | ENST00000375799 | + | 5 | 20 | 593_596 | 155 | 1020 | Compositional bias | Note=Poly-Leu |
| Hgene | >PLEKHM2 | chr1:16045120 | chr1:21573856 | ENST00000375799 | + | 5 | 20 | 771_873 | 155 | 1020 | Domain | PH |
| Tgene | ECE1 | chr1:16045120 | chr1:21573856 | ENST00000264205 | - | 6 | 18 | 1_68 | 337 | 768 | Topological domain | Cytoplasmic |
| Tgene | ECE1 | chr1:16045120 | chr1:21573856 | ENST00000264205 | - | 6 | 18 | 90_770 | 337 | 768 | Topological domain | Extracellular |
| Tgene | ECE1 | chr1:16045120 | chr1:21573856 | ENST00000357071 | - | 5 | 17 | 1_68 | 328 | 759 | Topological domain | Cytoplasmic |
| Tgene | ECE1 | chr1:16045120 | chr1:21573856 | ENST00000357071 | - | 5 | 17 | 90_770 | 328 | 759 | Topological domain | Extracellular |
| Tgene | ECE1 | chr1:16045120 | chr1:21573856 | ENST00000374893 | - | 7 | 19 | 1_68 | 340 | 771 | Topological domain | Cytoplasmic |
| Tgene | ECE1 | chr1:16045120 | chr1:21573856 | ENST00000374893 | - | 7 | 19 | 90_770 | 340 | 771 | Topological domain | Extracellular |
| Tgene | ECE1 | chr1:16045120 | chr1:21573856 | ENST00000415912 | - | 7 | 19 | 1_68 | 324 | 755 | Topological domain | Cytoplasmic |
| Tgene | ECE1 | chr1:16045120 | chr1:21573856 | ENST00000415912 | - | 7 | 19 | 90_770 | 324 | 755 | Topological domain | Extracellular |
| Tgene | ECE1 | chr1:16045120 | chr1:21573856 | ENST00000264205 | - | 6 | 18 | 69_89 | 337 | 768 | Transmembrane | Helical%3B Signal-anchor for type II membrane protein |
| Tgene | ECE1 | chr1:16045120 | chr1:21573856 | ENST00000357071 | - | 5 | 17 | 69_89 | 328 | 759 | Transmembrane | Helical%3B Signal-anchor for type II membrane protein |
| Tgene | ECE1 | chr1:16045120 | chr1:21573856 | ENST00000374893 | - | 7 | 19 | 69_89 | 340 | 771 | Transmembrane | Helical%3B Signal-anchor for type II membrane protein |
| Tgene | ECE1 | chr1:16045120 | chr1:21573856 | ENST00000415912 | - | 7 | 19 | 69_89 | 324 | 755 | Transmembrane | Helical%3B Signal-anchor for type II membrane protein |
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FusionGeneSequence for PLEKHM2_ECE1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_PLEKHM2_ENST00000375799_chr1_16045120_+_ECE1_ENST00000415912_chr1_21573856_-_586aa MEPGEVKDRILENISLSVKKLQSYFAACEDEIPAIRNHDKVLQRLCEHLDHALLYGLQDLSSGYWVLVVHFTRREAIKQIEVLQHVATNL GRSRAWLYLALNENSLESYLRLFQENLGLLHKYYVKNALVCSHDHLTLFLTLVSGLEFIRFELDLTLAPAINWLPFLNTIFYPVEINESE PIVVYDKEYLEQISTLINTTDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMFVKAT FAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVT ADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSV EAFKRQTECMVEQYSNYSVNGEPVNGRHTLGENIADNGGLKAAYRAYQNWVKKNGAEHSLPTLGLTNNQLFFLGFAQVWCSVRTPESSHE >In-frame_PLEKHM2_ENST00000375799_chr1_16045120_+_ECE1_ENST00000357071_chr1_21573856_-_586aa MEPGEVKDRILENISLSVKKLQSYFAACEDEIPAIRNHDKVLQRLCEHLDHALLYGLQDLSSGYWVLVVHFTRREAIKQIEVLQHVATNL GRSRAWLYLALNENSLESYLRLFQENLGLLHKYYVKNALVCSHDHLTLFLTLVSGLEFIRFELDLTLAPAINWLPFLNTIFYPVEINESE PIVVYDKEYLEQISTLINTTDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMFVKAT FAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVT ADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSV EAFKRQTECMVEQYSNYSVNGEPVNGRHTLGENIADNGGLKAAYRAYQNWVKKNGAEHSLPTLGLTNNQLFFLGFAQVWCSVRTPESSHE >In-frame_PLEKHM2_ENST00000375799_chr1_16045120_+_ECE1_ENST00000374893_chr1_21573856_-_586aa MEPGEVKDRILENISLSVKKLQSYFAACEDEIPAIRNHDKVLQRLCEHLDHALLYGLQDLSSGYWVLVVHFTRREAIKQIEVLQHVATNL GRSRAWLYLALNENSLESYLRLFQENLGLLHKYYVKNALVCSHDHLTLFLTLVSGLEFIRFELDLTLAPAINWLPFLNTIFYPVEINESE PIVVYDKEYLEQISTLINTTDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMFVKAT FAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVT ADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSV EAFKRQTECMVEQYSNYSVNGEPVNGRHTLGENIADNGGLKAAYRAYQNWVKKNGAEHSLPTLGLTNNQLFFLGFAQVWCSVRTPESSHE >In-frame_PLEKHM2_ENST00000375799_chr1_16045120_+_ECE1_ENST00000436918_chr1_21573856_-_554aa MEPGEVKDRILENISLSVKKLQSYFAACEDEIPAIRNHDKVLQRLCEHLDHALLYGLQDLSSGYWVLVVHFTRREAIKQIEVLQHVATNL GRSRAWLYLALNENSLESYLRLFQENLGLLHKYYVKNALVCSHDHLTLFLTLVSGLEFIRFELDLTLAPAINWLPFLNTIFYPVEINESE PIVVYDKEYLEQISTLINTTDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMFVKAT FAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVT ADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSV EAFKRQTECMVEQYSNYSVNGEPVNGRHTLGENIADNGGLKAAYRVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPP >In-frame_PLEKHM2_ENST00000375799_chr1_16045120_+_ECE1_ENST00000264205_chr1_21573856_-_586aa MEPGEVKDRILENISLSVKKLQSYFAACEDEIPAIRNHDKVLQRLCEHLDHALLYGLQDLSSGYWVLVVHFTRREAIKQIEVLQHVATNL GRSRAWLYLALNENSLESYLRLFQENLGLLHKYYVKNALVCSHDHLTLFLTLVSGLEFIRFELDLTLAPAINWLPFLNTIFYPVEINESE PIVVYDKEYLEQISTLINTTDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMFVKAT FAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVT ADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSV EAFKRQTECMVEQYSNYSVNGEPVNGRHTLGENIADNGGLKAAYRAYQNWVKKNGAEHSLPTLGLTNNQLFFLGFAQVWCSVRTPESSHE >In-frame_PLEKHM2_ENST00000375793_chr1_16045120_+_ECE1_ENST00000415912_chr1_21573856_-_586aa MEPGEVKDRILENISLSVKKLQSYFAACEDEIPAIRNHDKVLQRLCEHLDHALLYGLQDLSSGYWVLVVHFTRREAIKQIEVLQHVATNL GRSRAWLYLALNENSLESYLRLFQENLGLLHKYYVKNALVCSHDHLTLFLTLVSGLEFIRFELDLTLAPAINWLPFLNTIFYPVEINESE PIVVYDKEYLEQISTLINTTDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMFVKAT FAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVT ADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSV EAFKRQTECMVEQYSNYSVNGEPVNGRHTLGENIADNGGLKAAYRAYQNWVKKNGAEHSLPTLGLTNNQLFFLGFAQVWCSVRTPESSHE >In-frame_PLEKHM2_ENST00000375793_chr1_16045120_+_ECE1_ENST00000357071_chr1_21573856_-_586aa MEPGEVKDRILENISLSVKKLQSYFAACEDEIPAIRNHDKVLQRLCEHLDHALLYGLQDLSSGYWVLVVHFTRREAIKQIEVLQHVATNL GRSRAWLYLALNENSLESYLRLFQENLGLLHKYYVKNALVCSHDHLTLFLTLVSGLEFIRFELDLTLAPAINWLPFLNTIFYPVEINESE PIVVYDKEYLEQISTLINTTDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMFVKAT FAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVT ADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSV EAFKRQTECMVEQYSNYSVNGEPVNGRHTLGENIADNGGLKAAYRAYQNWVKKNGAEHSLPTLGLTNNQLFFLGFAQVWCSVRTPESSHE >In-frame_PLEKHM2_ENST00000375793_chr1_16045120_+_ECE1_ENST00000374893_chr1_21573856_-_586aa MEPGEVKDRILENISLSVKKLQSYFAACEDEIPAIRNHDKVLQRLCEHLDHALLYGLQDLSSGYWVLVVHFTRREAIKQIEVLQHVATNL GRSRAWLYLALNENSLESYLRLFQENLGLLHKYYVKNALVCSHDHLTLFLTLVSGLEFIRFELDLTLAPAINWLPFLNTIFYPVEINESE PIVVYDKEYLEQISTLINTTDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMFVKAT FAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVT ADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSV EAFKRQTECMVEQYSNYSVNGEPVNGRHTLGENIADNGGLKAAYRAYQNWVKKNGAEHSLPTLGLTNNQLFFLGFAQVWCSVRTPESSHE >In-frame_PLEKHM2_ENST00000375793_chr1_16045120_+_ECE1_ENST00000436918_chr1_21573856_-_554aa MEPGEVKDRILENISLSVKKLQSYFAACEDEIPAIRNHDKVLQRLCEHLDHALLYGLQDLSSGYWVLVVHFTRREAIKQIEVLQHVATNL GRSRAWLYLALNENSLESYLRLFQENLGLLHKYYVKNALVCSHDHLTLFLTLVSGLEFIRFELDLTLAPAINWLPFLNTIFYPVEINESE PIVVYDKEYLEQISTLINTTDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMFVKAT FAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVT ADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSV EAFKRQTECMVEQYSNYSVNGEPVNGRHTLGENIADNGGLKAAYRVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPP >In-frame_PLEKHM2_ENST00000375793_chr1_16045120_+_ECE1_ENST00000264205_chr1_21573856_-_586aa MEPGEVKDRILENISLSVKKLQSYFAACEDEIPAIRNHDKVLQRLCEHLDHALLYGLQDLSSGYWVLVVHFTRREAIKQIEVLQHVATNL GRSRAWLYLALNENSLESYLRLFQENLGLLHKYYVKNALVCSHDHLTLFLTLVSGLEFIRFELDLTLAPAINWLPFLNTIFYPVEINESE PIVVYDKEYLEQISTLINTTDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMFVKAT FAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVT ADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSV EAFKRQTECMVEQYSNYSVNGEPVNGRHTLGENIADNGGLKAAYRAYQNWVKKNGAEHSLPTLGLTNNQLFFLGFAQVWCSVRTPESSHE |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_PLEKHM2_ENST00000375799_chr1_16045120_+_ECE1_ENST00000415912_chr1_21573856_-_1758nt ATGGAGCCGGGGGAGGTGAAGGACCGGATCCTGGAGAACATCTCGCTGTCGGTGAAGAAGTTGCAGAGCTATTTTGCTGCATGTGAGGAT GAGATCCCTGCCATCCGGAACCATGACAAGGTCCTACAGCGTCTGTGTGAGCACCTGGACCACGCCCTGCTGTACGGACTGCAAGACCTC TCCTCTGGCTACTGGGTGCTCGTGGTGCATTTTACTCGGAGAGAGGCCATCAAGCAGATCGAGGTGCTGCAGCACGTGGCCACCAACCTG GGGCGCAGCCGTGCCTGGCTGTACCTGGCCCTCAACGAGAACTCCTTGGAGAGCTACCTGCGGTTGTTCCAGGAGAACCTGGGCCTGCTG CATAAGTACTACGTCAAGAATGCCCTGGTCTGCAGCCACGATCACCTGACGCTCTTCCTGACCTTGGTGTCCGGGCTAGAGTTCATTCGT TTCGAGCTGGATCTGACCTTGGCACCCGCCATCAACTGGTTGCCTTTTCTCAACACCATCTTCTACCCCGTGGAGATCAATGAATCCGAG CCTATTGTGGTCTATGACAAGGAATACCTTGAGCAGATCTCCACTCTCATCAACACCACCGACAGATGCCTGCTCAACAACTACATGATC TGGAACCTGGTGCGGAAAACAAGCTCCTTCCTTGACCAGCGCTTTCAGGACGCCGATGAGAAGTTCATGGAAGTCATGTACGGGACCAAG AAGACCTGTCTTCCTCGCTGGAAGTTTTGCGTGAGTGACACAGAAAACAACCTGGGCTTTGCGTTGGGCCCCATGTTTGTCAAAGCAACC TTCGCCGAGGACAGCAAGAGCATAGCCACCGAGATCATCCTGGAGATTAAGAAGGCATTTGAGGAAAGCCTGAGCACCCTGAAGTGGATG GATGAGGAAACCCGAAAATCAGCCAAGGAAAAGGCCGATGCCATCTACAACATGATAGGATACCCCAACTTCATCATGGATCCCAAGGAG CTGGACAAAGTGTTTAATGACTACACTGCAGTTCCAGACCTCTACTTTGAAAATGCCATGCGGTTTTTCAACTTCTCATGGAGGGTCACT GCCGATCAGCTCAGGAAAGCCCCCAACAGAGATCAGTGGAGCATGACCCCGCCCATGGTGAACGCCTACTACTCGCCCACCAAGAATGAG ATTGTGTTTCCGGCCGGGATCCTGCAGGCACCATTCTACACACGCTCCTCACCCAAGGCCTTAAACTTTGGTGGCATAGGTGTCGTCGTG GGCCATGAGCTGACTCATGCTTTTGATGATCAAGGACGGGAGTATGACAAGGACGGGAACCTCCGGCCATGGTGGAAGAACTCATCCGTG GAGGCCTTCAAGCGTCAGACCGAGTGCATGGTAGAGCAGTACAGCAACTACAGCGTGAACGGGGAGCCGGTGAACGGGCGGCACACCCTG GGGGAGAACATCGCCGACAACGGGGGTCTCAAGGCGGCCTATCGGGCTTACCAGAACTGGGTGAAGAAGAACGGGGCTGAGCACTCGCTC CCCACCCTGGGCCTCACCAATAACCAGCTCTTCTTCCTGGGCTTTGCACAGGTCTGGTGCTCCGTCCGCACACCTGAGAGCTCCCACGAA GGCCTCATCACCGATCCCCACAGCCCCTCTCGCTTCCGGGTCATCGGCTCCCTCTCCAATTCCAAGGAGTTCTCAGAACACTTCCGCTGC >In-frame_PLEKHM2_ENST00000375799_chr1_16045120_+_ECE1_ENST00000357071_chr1_21573856_-_1758nt ATGGAGCCGGGGGAGGTGAAGGACCGGATCCTGGAGAACATCTCGCTGTCGGTGAAGAAGTTGCAGAGCTATTTTGCTGCATGTGAGGAT GAGATCCCTGCCATCCGGAACCATGACAAGGTCCTACAGCGTCTGTGTGAGCACCTGGACCACGCCCTGCTGTACGGACTGCAAGACCTC TCCTCTGGCTACTGGGTGCTCGTGGTGCATTTTACTCGGAGAGAGGCCATCAAGCAGATCGAGGTGCTGCAGCACGTGGCCACCAACCTG GGGCGCAGCCGTGCCTGGCTGTACCTGGCCCTCAACGAGAACTCCTTGGAGAGCTACCTGCGGTTGTTCCAGGAGAACCTGGGCCTGCTG CATAAGTACTACGTCAAGAATGCCCTGGTCTGCAGCCACGATCACCTGACGCTCTTCCTGACCTTGGTGTCCGGGCTAGAGTTCATTCGT TTCGAGCTGGATCTGACCTTGGCACCCGCCATCAACTGGTTGCCTTTTCTCAACACCATCTTCTACCCCGTGGAGATCAATGAATCCGAG CCTATTGTGGTCTATGACAAGGAATACCTTGAGCAGATCTCCACTCTCATCAACACCACCGACAGATGCCTGCTCAACAACTACATGATC TGGAACCTGGTGCGGAAAACAAGCTCCTTCCTTGACCAGCGCTTTCAGGACGCCGATGAGAAGTTCATGGAAGTCATGTACGGGACCAAG AAGACCTGTCTTCCTCGCTGGAAGTTTTGCGTGAGTGACACAGAAAACAACCTGGGCTTTGCGTTGGGCCCCATGTTTGTCAAAGCAACC TTCGCCGAGGACAGCAAGAGCATAGCCACCGAGATCATCCTGGAGATTAAGAAGGCATTTGAGGAAAGCCTGAGCACCCTGAAGTGGATG GATGAGGAAACCCGAAAATCAGCCAAGGAAAAGGCCGATGCCATCTACAACATGATAGGATACCCCAACTTCATCATGGATCCCAAGGAG CTGGACAAAGTGTTTAATGACTACACTGCAGTTCCAGACCTCTACTTTGAAAATGCCATGCGGTTTTTCAACTTCTCATGGAGGGTCACT GCCGATCAGCTCAGGAAAGCCCCCAACAGAGATCAGTGGAGCATGACCCCGCCCATGGTGAACGCCTACTACTCGCCCACCAAGAATGAG ATTGTGTTTCCGGCCGGGATCCTGCAGGCACCATTCTACACACGCTCCTCACCCAAGGCCTTAAACTTTGGTGGCATAGGTGTCGTCGTG GGCCATGAGCTGACTCATGCTTTTGATGATCAAGGACGGGAGTATGACAAGGACGGGAACCTCCGGCCATGGTGGAAGAACTCATCCGTG GAGGCCTTCAAGCGTCAGACCGAGTGCATGGTAGAGCAGTACAGCAACTACAGCGTGAACGGGGAGCCGGTGAACGGGCGGCACACCCTG GGGGAGAACATCGCCGACAACGGGGGTCTCAAGGCGGCCTATCGGGCTTACCAGAACTGGGTGAAGAAGAACGGGGCTGAGCACTCGCTC CCCACCCTGGGCCTCACCAATAACCAGCTCTTCTTCCTGGGCTTTGCACAGGTCTGGTGCTCCGTCCGCACACCTGAGAGCTCCCACGAA GGCCTCATCACCGATCCCCACAGCCCCTCTCGCTTCCGGGTCATCGGCTCCCTCTCCAATTCCAAGGAGTTCTCAGAACACTTCCGCTGC >In-frame_PLEKHM2_ENST00000375799_chr1_16045120_+_ECE1_ENST00000374893_chr1_21573856_-_1758nt ATGGAGCCGGGGGAGGTGAAGGACCGGATCCTGGAGAACATCTCGCTGTCGGTGAAGAAGTTGCAGAGCTATTTTGCTGCATGTGAGGAT GAGATCCCTGCCATCCGGAACCATGACAAGGTCCTACAGCGTCTGTGTGAGCACCTGGACCACGCCCTGCTGTACGGACTGCAAGACCTC TCCTCTGGCTACTGGGTGCTCGTGGTGCATTTTACTCGGAGAGAGGCCATCAAGCAGATCGAGGTGCTGCAGCACGTGGCCACCAACCTG GGGCGCAGCCGTGCCTGGCTGTACCTGGCCCTCAACGAGAACTCCTTGGAGAGCTACCTGCGGTTGTTCCAGGAGAACCTGGGCCTGCTG CATAAGTACTACGTCAAGAATGCCCTGGTCTGCAGCCACGATCACCTGACGCTCTTCCTGACCTTGGTGTCCGGGCTAGAGTTCATTCGT TTCGAGCTGGATCTGACCTTGGCACCCGCCATCAACTGGTTGCCTTTTCTCAACACCATCTTCTACCCCGTGGAGATCAATGAATCCGAG CCTATTGTGGTCTATGACAAGGAATACCTTGAGCAGATCTCCACTCTCATCAACACCACCGACAGATGCCTGCTCAACAACTACATGATC TGGAACCTGGTGCGGAAAACAAGCTCCTTCCTTGACCAGCGCTTTCAGGACGCCGATGAGAAGTTCATGGAAGTCATGTACGGGACCAAG AAGACCTGTCTTCCTCGCTGGAAGTTTTGCGTGAGTGACACAGAAAACAACCTGGGCTTTGCGTTGGGCCCCATGTTTGTCAAAGCAACC TTCGCCGAGGACAGCAAGAGCATAGCCACCGAGATCATCCTGGAGATTAAGAAGGCATTTGAGGAAAGCCTGAGCACCCTGAAGTGGATG GATGAGGAAACCCGAAAATCAGCCAAGGAAAAGGCCGATGCCATCTACAACATGATAGGATACCCCAACTTCATCATGGATCCCAAGGAG CTGGACAAAGTGTTTAATGACTACACTGCAGTTCCAGACCTCTACTTTGAAAATGCCATGCGGTTTTTCAACTTCTCATGGAGGGTCACT GCCGATCAGCTCAGGAAAGCCCCCAACAGAGATCAGTGGAGCATGACCCCGCCCATGGTGAACGCCTACTACTCGCCCACCAAGAATGAG ATTGTGTTTCCGGCCGGGATCCTGCAGGCACCATTCTACACACGCTCCTCACCCAAGGCCTTAAACTTTGGTGGCATAGGTGTCGTCGTG GGCCATGAGCTGACTCATGCTTTTGATGATCAAGGACGGGAGTATGACAAGGACGGGAACCTCCGGCCATGGTGGAAGAACTCATCCGTG GAGGCCTTCAAGCGTCAGACCGAGTGCATGGTAGAGCAGTACAGCAACTACAGCGTGAACGGGGAGCCGGTGAACGGGCGGCACACCCTG GGGGAGAACATCGCCGACAACGGGGGTCTCAAGGCGGCCTATCGGGCTTACCAGAACTGGGTGAAGAAGAACGGGGCTGAGCACTCGCTC CCCACCCTGGGCCTCACCAATAACCAGCTCTTCTTCCTGGGCTTTGCACAGGTCTGGTGCTCCGTCCGCACACCTGAGAGCTCCCACGAA GGCCTCATCACCGATCCCCACAGCCCCTCTCGCTTCCGGGTCATCGGCTCCCTCTCCAATTCCAAGGAGTTCTCAGAACACTTCCGCTGC >In-frame_PLEKHM2_ENST00000375799_chr1_16045120_+_ECE1_ENST00000436918_chr1_21573856_-_1662nt ATGGAGCCGGGGGAGGTGAAGGACCGGATCCTGGAGAACATCTCGCTGTCGGTGAAGAAGTTGCAGAGCTATTTTGCTGCATGTGAGGAT GAGATCCCTGCCATCCGGAACCATGACAAGGTCCTACAGCGTCTGTGTGAGCACCTGGACCACGCCCTGCTGTACGGACTGCAAGACCTC TCCTCTGGCTACTGGGTGCTCGTGGTGCATTTTACTCGGAGAGAGGCCATCAAGCAGATCGAGGTGCTGCAGCACGTGGCCACCAACCTG GGGCGCAGCCGTGCCTGGCTGTACCTGGCCCTCAACGAGAACTCCTTGGAGAGCTACCTGCGGTTGTTCCAGGAGAACCTGGGCCTGCTG CATAAGTACTACGTCAAGAATGCCCTGGTCTGCAGCCACGATCACCTGACGCTCTTCCTGACCTTGGTGTCCGGGCTAGAGTTCATTCGT TTCGAGCTGGATCTGACCTTGGCACCCGCCATCAACTGGTTGCCTTTTCTCAACACCATCTTCTACCCCGTGGAGATCAATGAATCCGAG CCTATTGTGGTCTATGACAAGGAATACCTTGAGCAGATCTCCACTCTCATCAACACCACCGACAGATGCCTGCTCAACAACTACATGATC TGGAACCTGGTGCGGAAAACAAGCTCCTTCCTTGACCAGCGCTTTCAGGACGCCGATGAGAAGTTCATGGAAGTCATGTACGGGACCAAG AAGACCTGTCTTCCTCGCTGGAAGTTTTGCGTGAGTGACACAGAAAACAACCTGGGCTTTGCGTTGGGCCCCATGTTTGTCAAAGCAACC TTCGCCGAGGACAGCAAGAGCATAGCCACCGAGATCATCCTGGAGATTAAGAAGGCATTTGAGGAAAGCCTGAGCACCCTGAAGTGGATG GATGAGGAAACCCGAAAATCAGCCAAGGAAAAGGCCGATGCCATCTACAACATGATAGGATACCCCAACTTCATCATGGATCCCAAGGAG CTGGACAAAGTGTTTAATGACTACACTGCAGTTCCAGACCTCTACTTTGAAAATGCCATGCGGTTTTTCAACTTCTCATGGAGGGTCACT GCCGATCAGCTCAGGAAAGCCCCCAACAGAGATCAGTGGAGCATGACCCCGCCCATGGTGAACGCCTACTACTCGCCCACCAAGAATGAG ATTGTGTTTCCGGCCGGGATCCTGCAGGCACCATTCTACACACGCTCCTCACCCAAGGCCTTAAACTTTGGTGGCATAGGTGTCGTCGTG GGCCATGAGCTGACTCATGCTTTTGATGATCAAGGACGGGAGTATGACAAGGACGGGAACCTCCGGCCATGGTGGAAGAACTCATCCGTG GAGGCCTTCAAGCGTCAGACCGAGTGCATGGTAGAGCAGTACAGCAACTACAGCGTGAACGGGGAGCCGGTGAACGGGCGGCACACCCTG GGGGAGAACATCGCCGACAACGGGGGTCTCAAGGCGGCCTATCGGGTCTGGTGCTCCGTCCGCACACCTGAGAGCTCCCACGAAGGCCTC ATCACCGATCCCCACAGCCCCTCTCGCTTCCGGGTCATCGGCTCCCTCTCCAATTCCAAGGAGTTCTCAGAACACTTCCGCTGCCCACCT >In-frame_PLEKHM2_ENST00000375799_chr1_16045120_+_ECE1_ENST00000264205_chr1_21573856_-_1758nt ATGGAGCCGGGGGAGGTGAAGGACCGGATCCTGGAGAACATCTCGCTGTCGGTGAAGAAGTTGCAGAGCTATTTTGCTGCATGTGAGGAT GAGATCCCTGCCATCCGGAACCATGACAAGGTCCTACAGCGTCTGTGTGAGCACCTGGACCACGCCCTGCTGTACGGACTGCAAGACCTC TCCTCTGGCTACTGGGTGCTCGTGGTGCATTTTACTCGGAGAGAGGCCATCAAGCAGATCGAGGTGCTGCAGCACGTGGCCACCAACCTG GGGCGCAGCCGTGCCTGGCTGTACCTGGCCCTCAACGAGAACTCCTTGGAGAGCTACCTGCGGTTGTTCCAGGAGAACCTGGGCCTGCTG CATAAGTACTACGTCAAGAATGCCCTGGTCTGCAGCCACGATCACCTGACGCTCTTCCTGACCTTGGTGTCCGGGCTAGAGTTCATTCGT TTCGAGCTGGATCTGACCTTGGCACCCGCCATCAACTGGTTGCCTTTTCTCAACACCATCTTCTACCCCGTGGAGATCAATGAATCCGAG CCTATTGTGGTCTATGACAAGGAATACCTTGAGCAGATCTCCACTCTCATCAACACCACCGACAGATGCCTGCTCAACAACTACATGATC TGGAACCTGGTGCGGAAAACAAGCTCCTTCCTTGACCAGCGCTTTCAGGACGCCGATGAGAAGTTCATGGAAGTCATGTACGGGACCAAG AAGACCTGTCTTCCTCGCTGGAAGTTTTGCGTGAGTGACACAGAAAACAACCTGGGCTTTGCGTTGGGCCCCATGTTTGTCAAAGCAACC TTCGCCGAGGACAGCAAGAGCATAGCCACCGAGATCATCCTGGAGATTAAGAAGGCATTTGAGGAAAGCCTGAGCACCCTGAAGTGGATG GATGAGGAAACCCGAAAATCAGCCAAGGAAAAGGCCGATGCCATCTACAACATGATAGGATACCCCAACTTCATCATGGATCCCAAGGAG CTGGACAAAGTGTTTAATGACTACACTGCAGTTCCAGACCTCTACTTTGAAAATGCCATGCGGTTTTTCAACTTCTCATGGAGGGTCACT GCCGATCAGCTCAGGAAAGCCCCCAACAGAGATCAGTGGAGCATGACCCCGCCCATGGTGAACGCCTACTACTCGCCCACCAAGAATGAG ATTGTGTTTCCGGCCGGGATCCTGCAGGCACCATTCTACACACGCTCCTCACCCAAGGCCTTAAACTTTGGTGGCATAGGTGTCGTCGTG GGCCATGAGCTGACTCATGCTTTTGATGATCAAGGACGGGAGTATGACAAGGACGGGAACCTCCGGCCATGGTGGAAGAACTCATCCGTG GAGGCCTTCAAGCGTCAGACCGAGTGCATGGTAGAGCAGTACAGCAACTACAGCGTGAACGGGGAGCCGGTGAACGGGCGGCACACCCTG GGGGAGAACATCGCCGACAACGGGGGTCTCAAGGCGGCCTATCGGGCTTACCAGAACTGGGTGAAGAAGAACGGGGCTGAGCACTCGCTC CCCACCCTGGGCCTCACCAATAACCAGCTCTTCTTCCTGGGCTTTGCACAGGTCTGGTGCTCCGTCCGCACACCTGAGAGCTCCCACGAA GGCCTCATCACCGATCCCCACAGCCCCTCTCGCTTCCGGGTCATCGGCTCCCTCTCCAATTCCAAGGAGTTCTCAGAACACTTCCGCTGC >In-frame_PLEKHM2_ENST00000375793_chr1_16045120_+_ECE1_ENST00000415912_chr1_21573856_-_1758nt ATGGAGCCGGGGGAGGTGAAGGACCGGATCCTGGAGAACATCTCGCTGTCGGTGAAGAAGTTGCAGAGCTATTTTGCTGCATGTGAGGAT GAGATCCCTGCCATCCGGAACCATGACAAGGTCCTACAGCGTCTGTGTGAGCACCTGGACCACGCCCTGCTGTACGGACTGCAAGACCTC TCCTCTGGCTACTGGGTGCTCGTGGTGCATTTTACTCGGAGAGAGGCCATCAAGCAGATCGAGGTGCTGCAGCACGTGGCCACCAACCTG GGGCGCAGCCGTGCCTGGCTGTACCTGGCCCTCAACGAGAACTCCTTGGAGAGCTACCTGCGGTTGTTCCAGGAGAACCTGGGCCTGCTG CATAAGTACTACGTCAAGAATGCCCTGGTCTGCAGCCACGATCACCTGACGCTCTTCCTGACCTTGGTGTCCGGGCTAGAGTTCATTCGT TTCGAGCTGGATCTGACCTTGGCACCCGCCATCAACTGGTTGCCTTTTCTCAACACCATCTTCTACCCCGTGGAGATCAATGAATCCGAG CCTATTGTGGTCTATGACAAGGAATACCTTGAGCAGATCTCCACTCTCATCAACACCACCGACAGATGCCTGCTCAACAACTACATGATC TGGAACCTGGTGCGGAAAACAAGCTCCTTCCTTGACCAGCGCTTTCAGGACGCCGATGAGAAGTTCATGGAAGTCATGTACGGGACCAAG AAGACCTGTCTTCCTCGCTGGAAGTTTTGCGTGAGTGACACAGAAAACAACCTGGGCTTTGCGTTGGGCCCCATGTTTGTCAAAGCAACC TTCGCCGAGGACAGCAAGAGCATAGCCACCGAGATCATCCTGGAGATTAAGAAGGCATTTGAGGAAAGCCTGAGCACCCTGAAGTGGATG GATGAGGAAACCCGAAAATCAGCCAAGGAAAAGGCCGATGCCATCTACAACATGATAGGATACCCCAACTTCATCATGGATCCCAAGGAG CTGGACAAAGTGTTTAATGACTACACTGCAGTTCCAGACCTCTACTTTGAAAATGCCATGCGGTTTTTCAACTTCTCATGGAGGGTCACT GCCGATCAGCTCAGGAAAGCCCCCAACAGAGATCAGTGGAGCATGACCCCGCCCATGGTGAACGCCTACTACTCGCCCACCAAGAATGAG ATTGTGTTTCCGGCCGGGATCCTGCAGGCACCATTCTACACACGCTCCTCACCCAAGGCCTTAAACTTTGGTGGCATAGGTGTCGTCGTG GGCCATGAGCTGACTCATGCTTTTGATGATCAAGGACGGGAGTATGACAAGGACGGGAACCTCCGGCCATGGTGGAAGAACTCATCCGTG GAGGCCTTCAAGCGTCAGACCGAGTGCATGGTAGAGCAGTACAGCAACTACAGCGTGAACGGGGAGCCGGTGAACGGGCGGCACACCCTG GGGGAGAACATCGCCGACAACGGGGGTCTCAAGGCGGCCTATCGGGCTTACCAGAACTGGGTGAAGAAGAACGGGGCTGAGCACTCGCTC CCCACCCTGGGCCTCACCAATAACCAGCTCTTCTTCCTGGGCTTTGCACAGGTCTGGTGCTCCGTCCGCACACCTGAGAGCTCCCACGAA GGCCTCATCACCGATCCCCACAGCCCCTCTCGCTTCCGGGTCATCGGCTCCCTCTCCAATTCCAAGGAGTTCTCAGAACACTTCCGCTGC >In-frame_PLEKHM2_ENST00000375793_chr1_16045120_+_ECE1_ENST00000357071_chr1_21573856_-_1758nt ATGGAGCCGGGGGAGGTGAAGGACCGGATCCTGGAGAACATCTCGCTGTCGGTGAAGAAGTTGCAGAGCTATTTTGCTGCATGTGAGGAT GAGATCCCTGCCATCCGGAACCATGACAAGGTCCTACAGCGTCTGTGTGAGCACCTGGACCACGCCCTGCTGTACGGACTGCAAGACCTC TCCTCTGGCTACTGGGTGCTCGTGGTGCATTTTACTCGGAGAGAGGCCATCAAGCAGATCGAGGTGCTGCAGCACGTGGCCACCAACCTG GGGCGCAGCCGTGCCTGGCTGTACCTGGCCCTCAACGAGAACTCCTTGGAGAGCTACCTGCGGTTGTTCCAGGAGAACCTGGGCCTGCTG CATAAGTACTACGTCAAGAATGCCCTGGTCTGCAGCCACGATCACCTGACGCTCTTCCTGACCTTGGTGTCCGGGCTAGAGTTCATTCGT TTCGAGCTGGATCTGACCTTGGCACCCGCCATCAACTGGTTGCCTTTTCTCAACACCATCTTCTACCCCGTGGAGATCAATGAATCCGAG CCTATTGTGGTCTATGACAAGGAATACCTTGAGCAGATCTCCACTCTCATCAACACCACCGACAGATGCCTGCTCAACAACTACATGATC TGGAACCTGGTGCGGAAAACAAGCTCCTTCCTTGACCAGCGCTTTCAGGACGCCGATGAGAAGTTCATGGAAGTCATGTACGGGACCAAG AAGACCTGTCTTCCTCGCTGGAAGTTTTGCGTGAGTGACACAGAAAACAACCTGGGCTTTGCGTTGGGCCCCATGTTTGTCAAAGCAACC TTCGCCGAGGACAGCAAGAGCATAGCCACCGAGATCATCCTGGAGATTAAGAAGGCATTTGAGGAAAGCCTGAGCACCCTGAAGTGGATG GATGAGGAAACCCGAAAATCAGCCAAGGAAAAGGCCGATGCCATCTACAACATGATAGGATACCCCAACTTCATCATGGATCCCAAGGAG CTGGACAAAGTGTTTAATGACTACACTGCAGTTCCAGACCTCTACTTTGAAAATGCCATGCGGTTTTTCAACTTCTCATGGAGGGTCACT GCCGATCAGCTCAGGAAAGCCCCCAACAGAGATCAGTGGAGCATGACCCCGCCCATGGTGAACGCCTACTACTCGCCCACCAAGAATGAG ATTGTGTTTCCGGCCGGGATCCTGCAGGCACCATTCTACACACGCTCCTCACCCAAGGCCTTAAACTTTGGTGGCATAGGTGTCGTCGTG GGCCATGAGCTGACTCATGCTTTTGATGATCAAGGACGGGAGTATGACAAGGACGGGAACCTCCGGCCATGGTGGAAGAACTCATCCGTG GAGGCCTTCAAGCGTCAGACCGAGTGCATGGTAGAGCAGTACAGCAACTACAGCGTGAACGGGGAGCCGGTGAACGGGCGGCACACCCTG GGGGAGAACATCGCCGACAACGGGGGTCTCAAGGCGGCCTATCGGGCTTACCAGAACTGGGTGAAGAAGAACGGGGCTGAGCACTCGCTC CCCACCCTGGGCCTCACCAATAACCAGCTCTTCTTCCTGGGCTTTGCACAGGTCTGGTGCTCCGTCCGCACACCTGAGAGCTCCCACGAA GGCCTCATCACCGATCCCCACAGCCCCTCTCGCTTCCGGGTCATCGGCTCCCTCTCCAATTCCAAGGAGTTCTCAGAACACTTCCGCTGC >In-frame_PLEKHM2_ENST00000375793_chr1_16045120_+_ECE1_ENST00000374893_chr1_21573856_-_1758nt ATGGAGCCGGGGGAGGTGAAGGACCGGATCCTGGAGAACATCTCGCTGTCGGTGAAGAAGTTGCAGAGCTATTTTGCTGCATGTGAGGAT GAGATCCCTGCCATCCGGAACCATGACAAGGTCCTACAGCGTCTGTGTGAGCACCTGGACCACGCCCTGCTGTACGGACTGCAAGACCTC TCCTCTGGCTACTGGGTGCTCGTGGTGCATTTTACTCGGAGAGAGGCCATCAAGCAGATCGAGGTGCTGCAGCACGTGGCCACCAACCTG GGGCGCAGCCGTGCCTGGCTGTACCTGGCCCTCAACGAGAACTCCTTGGAGAGCTACCTGCGGTTGTTCCAGGAGAACCTGGGCCTGCTG CATAAGTACTACGTCAAGAATGCCCTGGTCTGCAGCCACGATCACCTGACGCTCTTCCTGACCTTGGTGTCCGGGCTAGAGTTCATTCGT TTCGAGCTGGATCTGACCTTGGCACCCGCCATCAACTGGTTGCCTTTTCTCAACACCATCTTCTACCCCGTGGAGATCAATGAATCCGAG CCTATTGTGGTCTATGACAAGGAATACCTTGAGCAGATCTCCACTCTCATCAACACCACCGACAGATGCCTGCTCAACAACTACATGATC TGGAACCTGGTGCGGAAAACAAGCTCCTTCCTTGACCAGCGCTTTCAGGACGCCGATGAGAAGTTCATGGAAGTCATGTACGGGACCAAG AAGACCTGTCTTCCTCGCTGGAAGTTTTGCGTGAGTGACACAGAAAACAACCTGGGCTTTGCGTTGGGCCCCATGTTTGTCAAAGCAACC TTCGCCGAGGACAGCAAGAGCATAGCCACCGAGATCATCCTGGAGATTAAGAAGGCATTTGAGGAAAGCCTGAGCACCCTGAAGTGGATG GATGAGGAAACCCGAAAATCAGCCAAGGAAAAGGCCGATGCCATCTACAACATGATAGGATACCCCAACTTCATCATGGATCCCAAGGAG CTGGACAAAGTGTTTAATGACTACACTGCAGTTCCAGACCTCTACTTTGAAAATGCCATGCGGTTTTTCAACTTCTCATGGAGGGTCACT GCCGATCAGCTCAGGAAAGCCCCCAACAGAGATCAGTGGAGCATGACCCCGCCCATGGTGAACGCCTACTACTCGCCCACCAAGAATGAG ATTGTGTTTCCGGCCGGGATCCTGCAGGCACCATTCTACACACGCTCCTCACCCAAGGCCTTAAACTTTGGTGGCATAGGTGTCGTCGTG GGCCATGAGCTGACTCATGCTTTTGATGATCAAGGACGGGAGTATGACAAGGACGGGAACCTCCGGCCATGGTGGAAGAACTCATCCGTG GAGGCCTTCAAGCGTCAGACCGAGTGCATGGTAGAGCAGTACAGCAACTACAGCGTGAACGGGGAGCCGGTGAACGGGCGGCACACCCTG GGGGAGAACATCGCCGACAACGGGGGTCTCAAGGCGGCCTATCGGGCTTACCAGAACTGGGTGAAGAAGAACGGGGCTGAGCACTCGCTC CCCACCCTGGGCCTCACCAATAACCAGCTCTTCTTCCTGGGCTTTGCACAGGTCTGGTGCTCCGTCCGCACACCTGAGAGCTCCCACGAA GGCCTCATCACCGATCCCCACAGCCCCTCTCGCTTCCGGGTCATCGGCTCCCTCTCCAATTCCAAGGAGTTCTCAGAACACTTCCGCTGC >In-frame_PLEKHM2_ENST00000375793_chr1_16045120_+_ECE1_ENST00000436918_chr1_21573856_-_1662nt ATGGAGCCGGGGGAGGTGAAGGACCGGATCCTGGAGAACATCTCGCTGTCGGTGAAGAAGTTGCAGAGCTATTTTGCTGCATGTGAGGAT GAGATCCCTGCCATCCGGAACCATGACAAGGTCCTACAGCGTCTGTGTGAGCACCTGGACCACGCCCTGCTGTACGGACTGCAAGACCTC TCCTCTGGCTACTGGGTGCTCGTGGTGCATTTTACTCGGAGAGAGGCCATCAAGCAGATCGAGGTGCTGCAGCACGTGGCCACCAACCTG GGGCGCAGCCGTGCCTGGCTGTACCTGGCCCTCAACGAGAACTCCTTGGAGAGCTACCTGCGGTTGTTCCAGGAGAACCTGGGCCTGCTG CATAAGTACTACGTCAAGAATGCCCTGGTCTGCAGCCACGATCACCTGACGCTCTTCCTGACCTTGGTGTCCGGGCTAGAGTTCATTCGT TTCGAGCTGGATCTGACCTTGGCACCCGCCATCAACTGGTTGCCTTTTCTCAACACCATCTTCTACCCCGTGGAGATCAATGAATCCGAG CCTATTGTGGTCTATGACAAGGAATACCTTGAGCAGATCTCCACTCTCATCAACACCACCGACAGATGCCTGCTCAACAACTACATGATC TGGAACCTGGTGCGGAAAACAAGCTCCTTCCTTGACCAGCGCTTTCAGGACGCCGATGAGAAGTTCATGGAAGTCATGTACGGGACCAAG AAGACCTGTCTTCCTCGCTGGAAGTTTTGCGTGAGTGACACAGAAAACAACCTGGGCTTTGCGTTGGGCCCCATGTTTGTCAAAGCAACC TTCGCCGAGGACAGCAAGAGCATAGCCACCGAGATCATCCTGGAGATTAAGAAGGCATTTGAGGAAAGCCTGAGCACCCTGAAGTGGATG GATGAGGAAACCCGAAAATCAGCCAAGGAAAAGGCCGATGCCATCTACAACATGATAGGATACCCCAACTTCATCATGGATCCCAAGGAG CTGGACAAAGTGTTTAATGACTACACTGCAGTTCCAGACCTCTACTTTGAAAATGCCATGCGGTTTTTCAACTTCTCATGGAGGGTCACT GCCGATCAGCTCAGGAAAGCCCCCAACAGAGATCAGTGGAGCATGACCCCGCCCATGGTGAACGCCTACTACTCGCCCACCAAGAATGAG ATTGTGTTTCCGGCCGGGATCCTGCAGGCACCATTCTACACACGCTCCTCACCCAAGGCCTTAAACTTTGGTGGCATAGGTGTCGTCGTG GGCCATGAGCTGACTCATGCTTTTGATGATCAAGGACGGGAGTATGACAAGGACGGGAACCTCCGGCCATGGTGGAAGAACTCATCCGTG GAGGCCTTCAAGCGTCAGACCGAGTGCATGGTAGAGCAGTACAGCAACTACAGCGTGAACGGGGAGCCGGTGAACGGGCGGCACACCCTG GGGGAGAACATCGCCGACAACGGGGGTCTCAAGGCGGCCTATCGGGTCTGGTGCTCCGTCCGCACACCTGAGAGCTCCCACGAAGGCCTC ATCACCGATCCCCACAGCCCCTCTCGCTTCCGGGTCATCGGCTCCCTCTCCAATTCCAAGGAGTTCTCAGAACACTTCCGCTGCCCACCT >In-frame_PLEKHM2_ENST00000375793_chr1_16045120_+_ECE1_ENST00000264205_chr1_21573856_-_1758nt ATGGAGCCGGGGGAGGTGAAGGACCGGATCCTGGAGAACATCTCGCTGTCGGTGAAGAAGTTGCAGAGCTATTTTGCTGCATGTGAGGAT GAGATCCCTGCCATCCGGAACCATGACAAGGTCCTACAGCGTCTGTGTGAGCACCTGGACCACGCCCTGCTGTACGGACTGCAAGACCTC TCCTCTGGCTACTGGGTGCTCGTGGTGCATTTTACTCGGAGAGAGGCCATCAAGCAGATCGAGGTGCTGCAGCACGTGGCCACCAACCTG GGGCGCAGCCGTGCCTGGCTGTACCTGGCCCTCAACGAGAACTCCTTGGAGAGCTACCTGCGGTTGTTCCAGGAGAACCTGGGCCTGCTG CATAAGTACTACGTCAAGAATGCCCTGGTCTGCAGCCACGATCACCTGACGCTCTTCCTGACCTTGGTGTCCGGGCTAGAGTTCATTCGT TTCGAGCTGGATCTGACCTTGGCACCCGCCATCAACTGGTTGCCTTTTCTCAACACCATCTTCTACCCCGTGGAGATCAATGAATCCGAG CCTATTGTGGTCTATGACAAGGAATACCTTGAGCAGATCTCCACTCTCATCAACACCACCGACAGATGCCTGCTCAACAACTACATGATC TGGAACCTGGTGCGGAAAACAAGCTCCTTCCTTGACCAGCGCTTTCAGGACGCCGATGAGAAGTTCATGGAAGTCATGTACGGGACCAAG AAGACCTGTCTTCCTCGCTGGAAGTTTTGCGTGAGTGACACAGAAAACAACCTGGGCTTTGCGTTGGGCCCCATGTTTGTCAAAGCAACC TTCGCCGAGGACAGCAAGAGCATAGCCACCGAGATCATCCTGGAGATTAAGAAGGCATTTGAGGAAAGCCTGAGCACCCTGAAGTGGATG GATGAGGAAACCCGAAAATCAGCCAAGGAAAAGGCCGATGCCATCTACAACATGATAGGATACCCCAACTTCATCATGGATCCCAAGGAG CTGGACAAAGTGTTTAATGACTACACTGCAGTTCCAGACCTCTACTTTGAAAATGCCATGCGGTTTTTCAACTTCTCATGGAGGGTCACT GCCGATCAGCTCAGGAAAGCCCCCAACAGAGATCAGTGGAGCATGACCCCGCCCATGGTGAACGCCTACTACTCGCCCACCAAGAATGAG ATTGTGTTTCCGGCCGGGATCCTGCAGGCACCATTCTACACACGCTCCTCACCCAAGGCCTTAAACTTTGGTGGCATAGGTGTCGTCGTG GGCCATGAGCTGACTCATGCTTTTGATGATCAAGGACGGGAGTATGACAAGGACGGGAACCTCCGGCCATGGTGGAAGAACTCATCCGTG GAGGCCTTCAAGCGTCAGACCGAGTGCATGGTAGAGCAGTACAGCAACTACAGCGTGAACGGGGAGCCGGTGAACGGGCGGCACACCCTG GGGGAGAACATCGCCGACAACGGGGGTCTCAAGGCGGCCTATCGGGCTTACCAGAACTGGGTGAAGAAGAACGGGGCTGAGCACTCGCTC CCCACCCTGGGCCTCACCAATAACCAGCTCTTCTTCCTGGGCTTTGCACAGGTCTGGTGCTCCGTCCGCACACCTGAGAGCTCCCACGAA GGCCTCATCACCGATCCCCACAGCCCCTCTCGCTTCCGGGTCATCGGCTCCCTCTCCAATTCCAAGGAGTTCTCAGAACACTTCCGCTGC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_PLEKHM2_ENST00000375799_chr1_16045120_+_ECE1_ENST00000415912_chr1_21573856_-_4693nt GCCTCCTTCCCCGCCGGCCGCGCTCCGGAGCCTCCGGGCCGCGGTGGAGCGAGGGCCCAGGCGAGGCGAGGGCCGGGCGGCGGGCGCCGG GCCCCGCGGCCGGCACGACGGAGCCCCCGTACGGCCGGCGGCAGCGGTTGGCGGCGGCCCCCGGCCCCCGGCGCGGGAAGCGGCGGCGGG GCGGCGGCGGCGGTGGCGGTGGCGGTGGCGGCGACGGTGGCAGCGCCATGGAGCCGGGGGAGGTGAAGGACCGGATCCTGGAGAACATCT CGCTGTCGGTGAAGAAGTTGCAGAGCTATTTTGCTGCATGTGAGGATGAGATCCCTGCCATCCGGAACCATGACAAGGTCCTACAGCGTC TGTGTGAGCACCTGGACCACGCCCTGCTGTACGGACTGCAAGACCTCTCCTCTGGCTACTGGGTGCTCGTGGTGCATTTTACTCGGAGAG AGGCCATCAAGCAGATCGAGGTGCTGCAGCACGTGGCCACCAACCTGGGGCGCAGCCGTGCCTGGCTGTACCTGGCCCTCAACGAGAACT CCTTGGAGAGCTACCTGCGGTTGTTCCAGGAGAACCTGGGCCTGCTGCATAAGTACTACGTCAAGAATGCCCTGGTCTGCAGCCACGATC ACCTGACGCTCTTCCTGACCTTGGTGTCCGGGCTAGAGTTCATTCGTTTCGAGCTGGATCTGACCTTGGCACCCGCCATCAACTGGTTGC CTTTTCTCAACACCATCTTCTACCCCGTGGAGATCAATGAATCCGAGCCTATTGTGGTCTATGACAAGGAATACCTTGAGCAGATCTCCA CTCTCATCAACACCACCGACAGATGCCTGCTCAACAACTACATGATCTGGAACCTGGTGCGGAAAACAAGCTCCTTCCTTGACCAGCGCT TTCAGGACGCCGATGAGAAGTTCATGGAAGTCATGTACGGGACCAAGAAGACCTGTCTTCCTCGCTGGAAGTTTTGCGTGAGTGACACAG AAAACAACCTGGGCTTTGCGTTGGGCCCCATGTTTGTCAAAGCAACCTTCGCCGAGGACAGCAAGAGCATAGCCACCGAGATCATCCTGG AGATTAAGAAGGCATTTGAGGAAAGCCTGAGCACCCTGAAGTGGATGGATGAGGAAACCCGAAAATCAGCCAAGGAAAAGGCCGATGCCA TCTACAACATGATAGGATACCCCAACTTCATCATGGATCCCAAGGAGCTGGACAAAGTGTTTAATGACTACACTGCAGTTCCAGACCTCT ACTTTGAAAATGCCATGCGGTTTTTCAACTTCTCATGGAGGGTCACTGCCGATCAGCTCAGGAAAGCCCCCAACAGAGATCAGTGGAGCA TGACCCCGCCCATGGTGAACGCCTACTACTCGCCCACCAAGAATGAGATTGTGTTTCCGGCCGGGATCCTGCAGGCACCATTCTACACAC GCTCCTCACCCAAGGCCTTAAACTTTGGTGGCATAGGTGTCGTCGTGGGCCATGAGCTGACTCATGCTTTTGATGATCAAGGACGGGAGT ATGACAAGGACGGGAACCTCCGGCCATGGTGGAAGAACTCATCCGTGGAGGCCTTCAAGCGTCAGACCGAGTGCATGGTAGAGCAGTACA GCAACTACAGCGTGAACGGGGAGCCGGTGAACGGGCGGCACACCCTGGGGGAGAACATCGCCGACAACGGGGGTCTCAAGGCGGCCTATC GGGCTTACCAGAACTGGGTGAAGAAGAACGGGGCTGAGCACTCGCTCCCCACCCTGGGCCTCACCAATAACCAGCTCTTCTTCCTGGGCT TTGCACAGGTCTGGTGCTCCGTCCGCACACCTGAGAGCTCCCACGAAGGCCTCATCACCGATCCCCACAGCCCCTCTCGCTTCCGGGTCA TCGGCTCCCTCTCCAATTCCAAGGAGTTCTCAGAACACTTCCGCTGCCCACCTGGCTCACCCATGAACCCGCCTCACAAGTGCGAAGTCT GGTAAGGACGAAGCGGAGAGAGCCAAGACGGAGGAGGGGAAGGGGCTGAGGACGAGACCCCCATCCAGCCTCCAGGGCATTGCTCAGCCC GCTTGGCCACCCGGGGCCCTGCTTCCTCACACTGGCGGGTTTTCAGCCGGAACCGAGCCCATGGTGTTGGCTCTCAACGTGACCCGCAGT CTGATCCCCTGTGAAGAGCCGGACATCCCAGGCACACGTGTGCGCCACCTTCAGCAGGCATTCGGGTGCTGGGCTGGTGGCTCATCAGGC CTGGGCCCCACACTGACAAGCGCCAGATACGCCACAAATACCACTGTGTCAAATGCTTTCAAGATATATTTTTGGGGAAACTATTTTTTA AACACTGTGGAATACACTGGAAATCTTCAGGGAAAAACACATTTAAACACTTTTTTTTTTAAGGAAAGAATTGGTATATTTATTATGTTC TGTTTTTCTAAATAACCTGTGGACAAGGGAAGCCCCACTGATTTACTCCCTCTCTTCCCCACTCCCTGTGAGGCTGGGCTGAGGCACGGA TCCCTGGGCCACAGAGCAAGTCTCCAAATCAGACAGCTGCCTCAGCCCCTGGGATGTGTGATTTCAGCTCCTGTCACCTCATGCAAGGGC GTGGAGACCAGTAGAGGTGTGGAGGCCAGGCAGAGAGAGGAGCCTGCTCTGCGGGGGGCCCAGCTCATGGGCACTGCCCCTTCAGCTAGC CTGCCTCCGTCCCCTGAGTCCAACAGTGGGAGCCCTAGCTGGGAAGTTCTGATCCCCAAAGCCACAGCAGGGGACTGATGGCTATAGCAG AATGAGGTCGGGTCAGGACCCTCAAACACCATCTGGGAACACCAAGCACCCTGAATCGAGACTGCAGGAGCCCTGCGGGGTGAGACTGTG TCAGAGATACACTGCTGGCCACAAGTGTCCCCTCTCAGTCCCACCTTTTCGGGCTGTCCCATGTCTATCTCAGGGGCCCGTTACCTCTCT GCAGCAGTCCCCCATCCCAGCCACACCAGGGTCTGTCCGGCCAACCCTCTTCCCCAGGGAAAGGAGAAAAGAGAAAACAGGCTGGGCCCG GTGGCTCACTCCTGTAATCCCAGCACTTTGGGAGGTTGAGGTGGGCGGATCACCTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACGTG GTGAAACCCCATCTCTACTAAAAAAAATTACAAAAATTAGCCGGGAGTGGTGGTGGGCACCTGTAATCCCAGTTACTCGGGAGGCTGAGG CAAGAGAATCTCTTGAGCTCAGGAGGCAGAGGTTGCAGTGAGCTGAGATTGCGCCACTGCACTCCAGCCTGGGTGACAGAGGGAGACTCC GTCCCAAAAAAAAGAAAAGAGAAACAGCTGTCACCTCCCGCAGGACCCAAATCCTCTCTCTGAGCACCGTCATCCACCACATGGCTGGGC CTGGCTCCCAGGACCAGTCCAGTCCTCTAGTGCCTTATCTGAGGCTGCAGCCGCCAGTCTCCACCCCAAGGAGACAGCCCCTGCTCCTAG ATGCCCTTGGCCTCCGCAGTGCAGCCCCCAGGTGTCCTGACTGAAGCACAGGCCATAGCCCCATTTCCCCGGTGCCTGCAGGGCTAACCT CCACGGGAGCCCAGGAGCTCTGGCCGGCAGGTCCATGGCACAGGGCATCGGAAGACTGCAAAACTGCTGGACTTACCCTGGGCTGCAGTC CATTGTCGGCCCCTGGGTTGAATCAAGATAGTACTTGCAGCTAGATGGATGCTTTTAGCCAGGGGACATTGTGAGGGGAAGATTCCTCCA CCCAGTCTGGCCTGTGGTGTCTGTCTCCTCCCTGAGACCACAGCTTCTCCAGTAGCAGACTCATGGGCGCCACCAAGTGGAAGCACCTGG AGCGGCCTCTGCCATCCAGTGGGGAAGCCAGGCCCCGAGACGGAGGTGGGGGCAGCACGTGCCCTCCACAGCCACCGCTTTCCCGCCTCA GCAGCCCAGGCCTCCTGGCCCAGCCCTGCCTGGACAGTGCTCTCCCCTCACCCGGGAAGCTGGAATCCTCCTGCCCGAGAGGAAGCAGAC GGCACAGGGACACCCCTGCCACCTTGGGATCTGCCTCCAAGCTGGTGCAGGGTATCGAGAGTGGATTCCAGATGGAGGTCCTGGTCCCAG CACGCAGCAGTCCTGGTAGCTCTGCAGAGGAGACAGGAACCCGAGAAGTAGCTGAAGCAGAAGCCAGCCGCAGTCCCCTTGCCACATAGA GGCGGGCTTCTCCCAGCCATGGTGTCCCCTCTGCCTCCCCTCCCCCGACCCTCCTGCCTTCCGCGTGGAGGGTGGTGGTCCTGTAGTGTC AGCACCAGCACCATGGGCTTGGACCCCCTCCCTGGACACAGGCAGGTGTCCTAGGGCTGGGGGTGCAGCCCGAGGGAATGGAGACCACAC TCATGGCTCAGGTCTGCCGGGGCCGGCAGGGGGTTGGGGAAGAAGAGGGCTCAGGCCCAGCAGGGGTGGAAGCCCCTGCCACTGCCACTA CCCGCTCCAGAGCTTTAAGGAAAATGAAGTGAGACCCCTCCCCTTAGGCCTGGGGAGCCATAGGGCTGGCTTCTCTGTGGGTGCGTGGAC GTGGGGTTGGGAGCTGGGAATCTATTTTTTGTATTATGTTTTGAGCTACTGTAGTTTTGGCGTGGCACTATTGTAATGGAAATAAAATAC >In-frame_PLEKHM2_ENST00000375799_chr1_16045120_+_ECE1_ENST00000357071_chr1_21573856_-_3356nt GCCTCCTTCCCCGCCGGCCGCGCTCCGGAGCCTCCGGGCCGCGGTGGAGCGAGGGCCCAGGCGAGGCGAGGGCCGGGCGGCGGGCGCCGG GCCCCGCGGCCGGCACGACGGAGCCCCCGTACGGCCGGCGGCAGCGGTTGGCGGCGGCCCCCGGCCCCCGGCGCGGGAAGCGGCGGCGGG GCGGCGGCGGCGGTGGCGGTGGCGGTGGCGGCGACGGTGGCAGCGCCATGGAGCCGGGGGAGGTGAAGGACCGGATCCTGGAGAACATCT CGCTGTCGGTGAAGAAGTTGCAGAGCTATTTTGCTGCATGTGAGGATGAGATCCCTGCCATCCGGAACCATGACAAGGTCCTACAGCGTC TGTGTGAGCACCTGGACCACGCCCTGCTGTACGGACTGCAAGACCTCTCCTCTGGCTACTGGGTGCTCGTGGTGCATTTTACTCGGAGAG AGGCCATCAAGCAGATCGAGGTGCTGCAGCACGTGGCCACCAACCTGGGGCGCAGCCGTGCCTGGCTGTACCTGGCCCTCAACGAGAACT CCTTGGAGAGCTACCTGCGGTTGTTCCAGGAGAACCTGGGCCTGCTGCATAAGTACTACGTCAAGAATGCCCTGGTCTGCAGCCACGATC ACCTGACGCTCTTCCTGACCTTGGTGTCCGGGCTAGAGTTCATTCGTTTCGAGCTGGATCTGACCTTGGCACCCGCCATCAACTGGTTGC CTTTTCTCAACACCATCTTCTACCCCGTGGAGATCAATGAATCCGAGCCTATTGTGGTCTATGACAAGGAATACCTTGAGCAGATCTCCA CTCTCATCAACACCACCGACAGATGCCTGCTCAACAACTACATGATCTGGAACCTGGTGCGGAAAACAAGCTCCTTCCTTGACCAGCGCT TTCAGGACGCCGATGAGAAGTTCATGGAAGTCATGTACGGGACCAAGAAGACCTGTCTTCCTCGCTGGAAGTTTTGCGTGAGTGACACAG AAAACAACCTGGGCTTTGCGTTGGGCCCCATGTTTGTCAAAGCAACCTTCGCCGAGGACAGCAAGAGCATAGCCACCGAGATCATCCTGG AGATTAAGAAGGCATTTGAGGAAAGCCTGAGCACCCTGAAGTGGATGGATGAGGAAACCCGAAAATCAGCCAAGGAAAAGGCCGATGCCA TCTACAACATGATAGGATACCCCAACTTCATCATGGATCCCAAGGAGCTGGACAAAGTGTTTAATGACTACACTGCAGTTCCAGACCTCT ACTTTGAAAATGCCATGCGGTTTTTCAACTTCTCATGGAGGGTCACTGCCGATCAGCTCAGGAAAGCCCCCAACAGAGATCAGTGGAGCA TGACCCCGCCCATGGTGAACGCCTACTACTCGCCCACCAAGAATGAGATTGTGTTTCCGGCCGGGATCCTGCAGGCACCATTCTACACAC GCTCCTCACCCAAGGCCTTAAACTTTGGTGGCATAGGTGTCGTCGTGGGCCATGAGCTGACTCATGCTTTTGATGATCAAGGACGGGAGT ATGACAAGGACGGGAACCTCCGGCCATGGTGGAAGAACTCATCCGTGGAGGCCTTCAAGCGTCAGACCGAGTGCATGGTAGAGCAGTACA GCAACTACAGCGTGAACGGGGAGCCGGTGAACGGGCGGCACACCCTGGGGGAGAACATCGCCGACAACGGGGGTCTCAAGGCGGCCTATC GGGCTTACCAGAACTGGGTGAAGAAGAACGGGGCTGAGCACTCGCTCCCCACCCTGGGCCTCACCAATAACCAGCTCTTCTTCCTGGGCT TTGCACAGGTCTGGTGCTCCGTCCGCACACCTGAGAGCTCCCACGAAGGCCTCATCACCGATCCCCACAGCCCCTCTCGCTTCCGGGTCA TCGGCTCCCTCTCCAATTCCAAGGAGTTCTCAGAACACTTCCGCTGCCCACCTGGCTCACCCATGAACCCGCCTCACAAGTGCGAAGTCT GGTAAGGACGAAGCGGAGAGAGCCAAGACGGAGGAGGGGAAGGGGCTGAGGACGAGACCCCCATCCAGCCTCCAGGGCATTGCTCAGCCC GCTTGGCCACCCGGGGCCCTGCTTCCTCACACTGGCGGGTTTTCAGCCGGAACCGAGCCCATGGTGTTGGCTCTCAACGTGACCCGCAGT CTGATCCCCTGTGAAGAGCCGGACATCCCAGGCACACGTGTGCGCCACCTTCAGCAGGCATTCGGGTGCTGGGCTGGTGGCTCATCAGGC CTGGGCCCCACACTGACAAGCGCCAGATACGCCACAAATACCACTGTGTCAAATGCTTTCAAGATATATTTTTGGGGAAACTATTTTTTA AACACTGTGGAATACACTGGAAATCTTCAGGGAAAAACACATTTAAACACTTTTTTTTTTAAGGAAAGAATTGGTATATTTATTATGTTC TGTTTTTCTAAATAACCTGTGGACAAGGGAAGCCCCACTGATTTACTCCCTCTCTTCCCCACTCCCTGTGAGGCTGGGCTGAGGCACGGA TCCCTGGGCCACAGAGCAAGTCTCCAAATCAGACAGCTGCCTCAGCCCCTGGGATGTGTGATTTCAGCTCCTGTCACCTCATGCAAGGGC GTGGAGACCAGTAGAGGTGTGGAGGCCAGGCAGAGAGAGGAGCCTGCTCTGCGGGGGGCCCAGCTCATGGGCACTGCCCCTTCAGCTAGC CTGCCTCCGTCCCCTGAGTCCAACAGTGGGAGCCCTAGCTGGGAAGTTCTGATCCCCAAAGCCACAGCAGGGGACTGATGGCTATAGCAG AATGAGGTCGGGTCAGGACCCTCAAACACCATCTGGGAACACCAAGCACCCTGAATCGAGACTGCAGGAGCCCTGCGGGGTGAGACTGTG TCAGAGATACACTGCTGGCCACAAGTGTCCCCTCTCAGTCCCACCTTTTCGGGCTGTCCCATGTCTATCTCAGGGGCCCGTTACCTCTCT GCAGCAGTCCCCCATCCCAGCCACACCAGGGTCTGTCCGGCCAACCCTCTTCCCCAGGGAAAGGAGAAAAGAGAAAACAGGCTGGGCCCG GTGGCTCACTCCTGTAATCCCAGCACTTTGGGAGGTTGAGGTGGGCGGATCACCTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACGTG GTGAAACCCCATCTCTACTAAAAAAAATTACAAAAATTAGCCGGGAGTGGTGGTGGGCACCTGTAATCCCAGTTACTCGGGAGGCTGAGG CAAGAGAATCTCTTGAGCTCAGGAGGCAGAGGTTGCAGTGAGCTGAGATTGCGCCACTGCACTCCAGCCTGGGTGACAGAGGGAGACTCC >In-frame_PLEKHM2_ENST00000375799_chr1_16045120_+_ECE1_ENST00000374893_chr1_21573856_-_2081nt GCCTCCTTCCCCGCCGGCCGCGCTCCGGAGCCTCCGGGCCGCGGTGGAGCGAGGGCCCAGGCGAGGCGAGGGCCGGGCGGCGGGCGCCGG GCCCCGCGGCCGGCACGACGGAGCCCCCGTACGGCCGGCGGCAGCGGTTGGCGGCGGCCCCCGGCCCCCGGCGCGGGAAGCGGCGGCGGG GCGGCGGCGGCGGTGGCGGTGGCGGTGGCGGCGACGGTGGCAGCGCCATGGAGCCGGGGGAGGTGAAGGACCGGATCCTGGAGAACATCT CGCTGTCGGTGAAGAAGTTGCAGAGCTATTTTGCTGCATGTGAGGATGAGATCCCTGCCATCCGGAACCATGACAAGGTCCTACAGCGTC TGTGTGAGCACCTGGACCACGCCCTGCTGTACGGACTGCAAGACCTCTCCTCTGGCTACTGGGTGCTCGTGGTGCATTTTACTCGGAGAG AGGCCATCAAGCAGATCGAGGTGCTGCAGCACGTGGCCACCAACCTGGGGCGCAGCCGTGCCTGGCTGTACCTGGCCCTCAACGAGAACT CCTTGGAGAGCTACCTGCGGTTGTTCCAGGAGAACCTGGGCCTGCTGCATAAGTACTACGTCAAGAATGCCCTGGTCTGCAGCCACGATC ACCTGACGCTCTTCCTGACCTTGGTGTCCGGGCTAGAGTTCATTCGTTTCGAGCTGGATCTGACCTTGGCACCCGCCATCAACTGGTTGC CTTTTCTCAACACCATCTTCTACCCCGTGGAGATCAATGAATCCGAGCCTATTGTGGTCTATGACAAGGAATACCTTGAGCAGATCTCCA CTCTCATCAACACCACCGACAGATGCCTGCTCAACAACTACATGATCTGGAACCTGGTGCGGAAAACAAGCTCCTTCCTTGACCAGCGCT TTCAGGACGCCGATGAGAAGTTCATGGAAGTCATGTACGGGACCAAGAAGACCTGTCTTCCTCGCTGGAAGTTTTGCGTGAGTGACACAG AAAACAACCTGGGCTTTGCGTTGGGCCCCATGTTTGTCAAAGCAACCTTCGCCGAGGACAGCAAGAGCATAGCCACCGAGATCATCCTGG AGATTAAGAAGGCATTTGAGGAAAGCCTGAGCACCCTGAAGTGGATGGATGAGGAAACCCGAAAATCAGCCAAGGAAAAGGCCGATGCCA TCTACAACATGATAGGATACCCCAACTTCATCATGGATCCCAAGGAGCTGGACAAAGTGTTTAATGACTACACTGCAGTTCCAGACCTCT ACTTTGAAAATGCCATGCGGTTTTTCAACTTCTCATGGAGGGTCACTGCCGATCAGCTCAGGAAAGCCCCCAACAGAGATCAGTGGAGCA TGACCCCGCCCATGGTGAACGCCTACTACTCGCCCACCAAGAATGAGATTGTGTTTCCGGCCGGGATCCTGCAGGCACCATTCTACACAC GCTCCTCACCCAAGGCCTTAAACTTTGGTGGCATAGGTGTCGTCGTGGGCCATGAGCTGACTCATGCTTTTGATGATCAAGGACGGGAGT ATGACAAGGACGGGAACCTCCGGCCATGGTGGAAGAACTCATCCGTGGAGGCCTTCAAGCGTCAGACCGAGTGCATGGTAGAGCAGTACA GCAACTACAGCGTGAACGGGGAGCCGGTGAACGGGCGGCACACCCTGGGGGAGAACATCGCCGACAACGGGGGTCTCAAGGCGGCCTATC GGGCTTACCAGAACTGGGTGAAGAAGAACGGGGCTGAGCACTCGCTCCCCACCCTGGGCCTCACCAATAACCAGCTCTTCTTCCTGGGCT TTGCACAGGTCTGGTGCTCCGTCCGCACACCTGAGAGCTCCCACGAAGGCCTCATCACCGATCCCCACAGCCCCTCTCGCTTCCGGGTCA TCGGCTCCCTCTCCAATTCCAAGGAGTTCTCAGAACACTTCCGCTGCCCACCTGGCTCACCCATGAACCCGCCTCACAAGTGCGAAGTCT GGTAAGGACGAAGCGGAGAGAGCCAAGACGGAGGAGGGGAAGGGGCTGAGGACGAGACCCCCATCCAGCCTCCAGGGCATTGCTCAGCCC >In-frame_PLEKHM2_ENST00000375799_chr1_16045120_+_ECE1_ENST00000436918_chr1_21573856_-_1950nt GCCTCCTTCCCCGCCGGCCGCGCTCCGGAGCCTCCGGGCCGCGGTGGAGCGAGGGCCCAGGCGAGGCGAGGGCCGGGCGGCGGGCGCCGG GCCCCGCGGCCGGCACGACGGAGCCCCCGTACGGCCGGCGGCAGCGGTTGGCGGCGGCCCCCGGCCCCCGGCGCGGGAAGCGGCGGCGGG GCGGCGGCGGCGGTGGCGGTGGCGGTGGCGGCGACGGTGGCAGCGCCATGGAGCCGGGGGAGGTGAAGGACCGGATCCTGGAGAACATCT CGCTGTCGGTGAAGAAGTTGCAGAGCTATTTTGCTGCATGTGAGGATGAGATCCCTGCCATCCGGAACCATGACAAGGTCCTACAGCGTC TGTGTGAGCACCTGGACCACGCCCTGCTGTACGGACTGCAAGACCTCTCCTCTGGCTACTGGGTGCTCGTGGTGCATTTTACTCGGAGAG AGGCCATCAAGCAGATCGAGGTGCTGCAGCACGTGGCCACCAACCTGGGGCGCAGCCGTGCCTGGCTGTACCTGGCCCTCAACGAGAACT CCTTGGAGAGCTACCTGCGGTTGTTCCAGGAGAACCTGGGCCTGCTGCATAAGTACTACGTCAAGAATGCCCTGGTCTGCAGCCACGATC ACCTGACGCTCTTCCTGACCTTGGTGTCCGGGCTAGAGTTCATTCGTTTCGAGCTGGATCTGACCTTGGCACCCGCCATCAACTGGTTGC CTTTTCTCAACACCATCTTCTACCCCGTGGAGATCAATGAATCCGAGCCTATTGTGGTCTATGACAAGGAATACCTTGAGCAGATCTCCA CTCTCATCAACACCACCGACAGATGCCTGCTCAACAACTACATGATCTGGAACCTGGTGCGGAAAACAAGCTCCTTCCTTGACCAGCGCT TTCAGGACGCCGATGAGAAGTTCATGGAAGTCATGTACGGGACCAAGAAGACCTGTCTTCCTCGCTGGAAGTTTTGCGTGAGTGACACAG AAAACAACCTGGGCTTTGCGTTGGGCCCCATGTTTGTCAAAGCAACCTTCGCCGAGGACAGCAAGAGCATAGCCACCGAGATCATCCTGG AGATTAAGAAGGCATTTGAGGAAAGCCTGAGCACCCTGAAGTGGATGGATGAGGAAACCCGAAAATCAGCCAAGGAAAAGGCCGATGCCA TCTACAACATGATAGGATACCCCAACTTCATCATGGATCCCAAGGAGCTGGACAAAGTGTTTAATGACTACACTGCAGTTCCAGACCTCT ACTTTGAAAATGCCATGCGGTTTTTCAACTTCTCATGGAGGGTCACTGCCGATCAGCTCAGGAAAGCCCCCAACAGAGATCAGTGGAGCA TGACCCCGCCCATGGTGAACGCCTACTACTCGCCCACCAAGAATGAGATTGTGTTTCCGGCCGGGATCCTGCAGGCACCATTCTACACAC GCTCCTCACCCAAGGCCTTAAACTTTGGTGGCATAGGTGTCGTCGTGGGCCATGAGCTGACTCATGCTTTTGATGATCAAGGACGGGAGT ATGACAAGGACGGGAACCTCCGGCCATGGTGGAAGAACTCATCCGTGGAGGCCTTCAAGCGTCAGACCGAGTGCATGGTAGAGCAGTACA GCAACTACAGCGTGAACGGGGAGCCGGTGAACGGGCGGCACACCCTGGGGGAGAACATCGCCGACAACGGGGGTCTCAAGGCGGCCTATC GGGTCTGGTGCTCCGTCCGCACACCTGAGAGCTCCCACGAAGGCCTCATCACCGATCCCCACAGCCCCTCTCGCTTCCGGGTCATCGGCT CCCTCTCCAATTCCAAGGAGTTCTCAGAACACTTCCGCTGCCCACCTGGCTCACCCATGAACCCGCCTCACAAGTGCGAAGTCTGGTAAG >In-frame_PLEKHM2_ENST00000375799_chr1_16045120_+_ECE1_ENST00000264205_chr1_21573856_-_2003nt GCCTCCTTCCCCGCCGGCCGCGCTCCGGAGCCTCCGGGCCGCGGTGGAGCGAGGGCCCAGGCGAGGCGAGGGCCGGGCGGCGGGCGCCGG GCCCCGCGGCCGGCACGACGGAGCCCCCGTACGGCCGGCGGCAGCGGTTGGCGGCGGCCCCCGGCCCCCGGCGCGGGAAGCGGCGGCGGG GCGGCGGCGGCGGTGGCGGTGGCGGTGGCGGCGACGGTGGCAGCGCCATGGAGCCGGGGGAGGTGAAGGACCGGATCCTGGAGAACATCT CGCTGTCGGTGAAGAAGTTGCAGAGCTATTTTGCTGCATGTGAGGATGAGATCCCTGCCATCCGGAACCATGACAAGGTCCTACAGCGTC TGTGTGAGCACCTGGACCACGCCCTGCTGTACGGACTGCAAGACCTCTCCTCTGGCTACTGGGTGCTCGTGGTGCATTTTACTCGGAGAG AGGCCATCAAGCAGATCGAGGTGCTGCAGCACGTGGCCACCAACCTGGGGCGCAGCCGTGCCTGGCTGTACCTGGCCCTCAACGAGAACT CCTTGGAGAGCTACCTGCGGTTGTTCCAGGAGAACCTGGGCCTGCTGCATAAGTACTACGTCAAGAATGCCCTGGTCTGCAGCCACGATC ACCTGACGCTCTTCCTGACCTTGGTGTCCGGGCTAGAGTTCATTCGTTTCGAGCTGGATCTGACCTTGGCACCCGCCATCAACTGGTTGC CTTTTCTCAACACCATCTTCTACCCCGTGGAGATCAATGAATCCGAGCCTATTGTGGTCTATGACAAGGAATACCTTGAGCAGATCTCCA CTCTCATCAACACCACCGACAGATGCCTGCTCAACAACTACATGATCTGGAACCTGGTGCGGAAAACAAGCTCCTTCCTTGACCAGCGCT TTCAGGACGCCGATGAGAAGTTCATGGAAGTCATGTACGGGACCAAGAAGACCTGTCTTCCTCGCTGGAAGTTTTGCGTGAGTGACACAG AAAACAACCTGGGCTTTGCGTTGGGCCCCATGTTTGTCAAAGCAACCTTCGCCGAGGACAGCAAGAGCATAGCCACCGAGATCATCCTGG AGATTAAGAAGGCATTTGAGGAAAGCCTGAGCACCCTGAAGTGGATGGATGAGGAAACCCGAAAATCAGCCAAGGAAAAGGCCGATGCCA TCTACAACATGATAGGATACCCCAACTTCATCATGGATCCCAAGGAGCTGGACAAAGTGTTTAATGACTACACTGCAGTTCCAGACCTCT ACTTTGAAAATGCCATGCGGTTTTTCAACTTCTCATGGAGGGTCACTGCCGATCAGCTCAGGAAAGCCCCCAACAGAGATCAGTGGAGCA TGACCCCGCCCATGGTGAACGCCTACTACTCGCCCACCAAGAATGAGATTGTGTTTCCGGCCGGGATCCTGCAGGCACCATTCTACACAC GCTCCTCACCCAAGGCCTTAAACTTTGGTGGCATAGGTGTCGTCGTGGGCCATGAGCTGACTCATGCTTTTGATGATCAAGGACGGGAGT ATGACAAGGACGGGAACCTCCGGCCATGGTGGAAGAACTCATCCGTGGAGGCCTTCAAGCGTCAGACCGAGTGCATGGTAGAGCAGTACA GCAACTACAGCGTGAACGGGGAGCCGGTGAACGGGCGGCACACCCTGGGGGAGAACATCGCCGACAACGGGGGTCTCAAGGCGGCCTATC GGGCTTACCAGAACTGGGTGAAGAAGAACGGGGCTGAGCACTCGCTCCCCACCCTGGGCCTCACCAATAACCAGCTCTTCTTCCTGGGCT TTGCACAGGTCTGGTGCTCCGTCCGCACACCTGAGAGCTCCCACGAAGGCCTCATCACCGATCCCCACAGCCCCTCTCGCTTCCGGGTCA TCGGCTCCCTCTCCAATTCCAAGGAGTTCTCAGAACACTTCCGCTGCCCACCTGGCTCACCCATGAACCCGCCTCACAAGTGCGAAGTCT >In-frame_PLEKHM2_ENST00000375793_chr1_16045120_+_ECE1_ENST00000415912_chr1_21573856_-_4635nt AGGCGAGGCGAGGGCCGGGCGGCGGGCGCCGGGCCCCGCGGCCGGCACGACGGAGCCCCCGTACGGCCGGCGGCAGCGGTTGGCGGCGGC CCCCGGCCCCCGGCGCGGGAAGCGGCGGCGGGGCGGCGGCGGCGGTGGCGGTGGCGGTGGCGGCGACGGTGGCAGCGCCATGGAGCCGGG GGAGGTGAAGGACCGGATCCTGGAGAACATCTCGCTGTCGGTGAAGAAGTTGCAGAGCTATTTTGCTGCATGTGAGGATGAGATCCCTGC CATCCGGAACCATGACAAGGTCCTACAGCGTCTGTGTGAGCACCTGGACCACGCCCTGCTGTACGGACTGCAAGACCTCTCCTCTGGCTA CTGGGTGCTCGTGGTGCATTTTACTCGGAGAGAGGCCATCAAGCAGATCGAGGTGCTGCAGCACGTGGCCACCAACCTGGGGCGCAGCCG TGCCTGGCTGTACCTGGCCCTCAACGAGAACTCCTTGGAGAGCTACCTGCGGTTGTTCCAGGAGAACCTGGGCCTGCTGCATAAGTACTA CGTCAAGAATGCCCTGGTCTGCAGCCACGATCACCTGACGCTCTTCCTGACCTTGGTGTCCGGGCTAGAGTTCATTCGTTTCGAGCTGGA TCTGACCTTGGCACCCGCCATCAACTGGTTGCCTTTTCTCAACACCATCTTCTACCCCGTGGAGATCAATGAATCCGAGCCTATTGTGGT CTATGACAAGGAATACCTTGAGCAGATCTCCACTCTCATCAACACCACCGACAGATGCCTGCTCAACAACTACATGATCTGGAACCTGGT GCGGAAAACAAGCTCCTTCCTTGACCAGCGCTTTCAGGACGCCGATGAGAAGTTCATGGAAGTCATGTACGGGACCAAGAAGACCTGTCT TCCTCGCTGGAAGTTTTGCGTGAGTGACACAGAAAACAACCTGGGCTTTGCGTTGGGCCCCATGTTTGTCAAAGCAACCTTCGCCGAGGA CAGCAAGAGCATAGCCACCGAGATCATCCTGGAGATTAAGAAGGCATTTGAGGAAAGCCTGAGCACCCTGAAGTGGATGGATGAGGAAAC CCGAAAATCAGCCAAGGAAAAGGCCGATGCCATCTACAACATGATAGGATACCCCAACTTCATCATGGATCCCAAGGAGCTGGACAAAGT GTTTAATGACTACACTGCAGTTCCAGACCTCTACTTTGAAAATGCCATGCGGTTTTTCAACTTCTCATGGAGGGTCACTGCCGATCAGCT CAGGAAAGCCCCCAACAGAGATCAGTGGAGCATGACCCCGCCCATGGTGAACGCCTACTACTCGCCCACCAAGAATGAGATTGTGTTTCC GGCCGGGATCCTGCAGGCACCATTCTACACACGCTCCTCACCCAAGGCCTTAAACTTTGGTGGCATAGGTGTCGTCGTGGGCCATGAGCT GACTCATGCTTTTGATGATCAAGGACGGGAGTATGACAAGGACGGGAACCTCCGGCCATGGTGGAAGAACTCATCCGTGGAGGCCTTCAA GCGTCAGACCGAGTGCATGGTAGAGCAGTACAGCAACTACAGCGTGAACGGGGAGCCGGTGAACGGGCGGCACACCCTGGGGGAGAACAT CGCCGACAACGGGGGTCTCAAGGCGGCCTATCGGGCTTACCAGAACTGGGTGAAGAAGAACGGGGCTGAGCACTCGCTCCCCACCCTGGG CCTCACCAATAACCAGCTCTTCTTCCTGGGCTTTGCACAGGTCTGGTGCTCCGTCCGCACACCTGAGAGCTCCCACGAAGGCCTCATCAC CGATCCCCACAGCCCCTCTCGCTTCCGGGTCATCGGCTCCCTCTCCAATTCCAAGGAGTTCTCAGAACACTTCCGCTGCCCACCTGGCTC ACCCATGAACCCGCCTCACAAGTGCGAAGTCTGGTAAGGACGAAGCGGAGAGAGCCAAGACGGAGGAGGGGAAGGGGCTGAGGACGAGAC CCCCATCCAGCCTCCAGGGCATTGCTCAGCCCGCTTGGCCACCCGGGGCCCTGCTTCCTCACACTGGCGGGTTTTCAGCCGGAACCGAGC CCATGGTGTTGGCTCTCAACGTGACCCGCAGTCTGATCCCCTGTGAAGAGCCGGACATCCCAGGCACACGTGTGCGCCACCTTCAGCAGG CATTCGGGTGCTGGGCTGGTGGCTCATCAGGCCTGGGCCCCACACTGACAAGCGCCAGATACGCCACAAATACCACTGTGTCAAATGCTT TCAAGATATATTTTTGGGGAAACTATTTTTTAAACACTGTGGAATACACTGGAAATCTTCAGGGAAAAACACATTTAAACACTTTTTTTT TTAAGGAAAGAATTGGTATATTTATTATGTTCTGTTTTTCTAAATAACCTGTGGACAAGGGAAGCCCCACTGATTTACTCCCTCTCTTCC CCACTCCCTGTGAGGCTGGGCTGAGGCACGGATCCCTGGGCCACAGAGCAAGTCTCCAAATCAGACAGCTGCCTCAGCCCCTGGGATGTG TGATTTCAGCTCCTGTCACCTCATGCAAGGGCGTGGAGACCAGTAGAGGTGTGGAGGCCAGGCAGAGAGAGGAGCCTGCTCTGCGGGGGG CCCAGCTCATGGGCACTGCCCCTTCAGCTAGCCTGCCTCCGTCCCCTGAGTCCAACAGTGGGAGCCCTAGCTGGGAAGTTCTGATCCCCA AAGCCACAGCAGGGGACTGATGGCTATAGCAGAATGAGGTCGGGTCAGGACCCTCAAACACCATCTGGGAACACCAAGCACCCTGAATCG AGACTGCAGGAGCCCTGCGGGGTGAGACTGTGTCAGAGATACACTGCTGGCCACAAGTGTCCCCTCTCAGTCCCACCTTTTCGGGCTGTC CCATGTCTATCTCAGGGGCCCGTTACCTCTCTGCAGCAGTCCCCCATCCCAGCCACACCAGGGTCTGTCCGGCCAACCCTCTTCCCCAGG GAAAGGAGAAAAGAGAAAACAGGCTGGGCCCGGTGGCTCACTCCTGTAATCCCAGCACTTTGGGAGGTTGAGGTGGGCGGATCACCTGAG GTCAGGAGTTTGAGACCAGCCTGGCCAACGTGGTGAAACCCCATCTCTACTAAAAAAAATTACAAAAATTAGCCGGGAGTGGTGGTGGGC ACCTGTAATCCCAGTTACTCGGGAGGCTGAGGCAAGAGAATCTCTTGAGCTCAGGAGGCAGAGGTTGCAGTGAGCTGAGATTGCGCCACT GCACTCCAGCCTGGGTGACAGAGGGAGACTCCGTCCCAAAAAAAAGAAAAGAGAAACAGCTGTCACCTCCCGCAGGACCCAAATCCTCTC TCTGAGCACCGTCATCCACCACATGGCTGGGCCTGGCTCCCAGGACCAGTCCAGTCCTCTAGTGCCTTATCTGAGGCTGCAGCCGCCAGT CTCCACCCCAAGGAGACAGCCCCTGCTCCTAGATGCCCTTGGCCTCCGCAGTGCAGCCCCCAGGTGTCCTGACTGAAGCACAGGCCATAG CCCCATTTCCCCGGTGCCTGCAGGGCTAACCTCCACGGGAGCCCAGGAGCTCTGGCCGGCAGGTCCATGGCACAGGGCATCGGAAGACTG CAAAACTGCTGGACTTACCCTGGGCTGCAGTCCATTGTCGGCCCCTGGGTTGAATCAAGATAGTACTTGCAGCTAGATGGATGCTTTTAG CCAGGGGACATTGTGAGGGGAAGATTCCTCCACCCAGTCTGGCCTGTGGTGTCTGTCTCCTCCCTGAGACCACAGCTTCTCCAGTAGCAG ACTCATGGGCGCCACCAAGTGGAAGCACCTGGAGCGGCCTCTGCCATCCAGTGGGGAAGCCAGGCCCCGAGACGGAGGTGGGGGCAGCAC GTGCCCTCCACAGCCACCGCTTTCCCGCCTCAGCAGCCCAGGCCTCCTGGCCCAGCCCTGCCTGGACAGTGCTCTCCCCTCACCCGGGAA GCTGGAATCCTCCTGCCCGAGAGGAAGCAGACGGCACAGGGACACCCCTGCCACCTTGGGATCTGCCTCCAAGCTGGTGCAGGGTATCGA GAGTGGATTCCAGATGGAGGTCCTGGTCCCAGCACGCAGCAGTCCTGGTAGCTCTGCAGAGGAGACAGGAACCCGAGAAGTAGCTGAAGC AGAAGCCAGCCGCAGTCCCCTTGCCACATAGAGGCGGGCTTCTCCCAGCCATGGTGTCCCCTCTGCCTCCCCTCCCCCGACCCTCCTGCC TTCCGCGTGGAGGGTGGTGGTCCTGTAGTGTCAGCACCAGCACCATGGGCTTGGACCCCCTCCCTGGACACAGGCAGGTGTCCTAGGGCT GGGGGTGCAGCCCGAGGGAATGGAGACCACACTCATGGCTCAGGTCTGCCGGGGCCGGCAGGGGGTTGGGGAAGAAGAGGGCTCAGGCCC AGCAGGGGTGGAAGCCCCTGCCACTGCCACTACCCGCTCCAGAGCTTTAAGGAAAATGAAGTGAGACCCCTCCCCTTAGGCCTGGGGAGC CATAGGGCTGGCTTCTCTGTGGGTGCGTGGACGTGGGGTTGGGAGCTGGGAATCTATTTTTTGTATTATGTTTTGAGCTACTGTAGTTTT >In-frame_PLEKHM2_ENST00000375793_chr1_16045120_+_ECE1_ENST00000357071_chr1_21573856_-_3298nt AGGCGAGGCGAGGGCCGGGCGGCGGGCGCCGGGCCCCGCGGCCGGCACGACGGAGCCCCCGTACGGCCGGCGGCAGCGGTTGGCGGCGGC CCCCGGCCCCCGGCGCGGGAAGCGGCGGCGGGGCGGCGGCGGCGGTGGCGGTGGCGGTGGCGGCGACGGTGGCAGCGCCATGGAGCCGGG GGAGGTGAAGGACCGGATCCTGGAGAACATCTCGCTGTCGGTGAAGAAGTTGCAGAGCTATTTTGCTGCATGTGAGGATGAGATCCCTGC CATCCGGAACCATGACAAGGTCCTACAGCGTCTGTGTGAGCACCTGGACCACGCCCTGCTGTACGGACTGCAAGACCTCTCCTCTGGCTA CTGGGTGCTCGTGGTGCATTTTACTCGGAGAGAGGCCATCAAGCAGATCGAGGTGCTGCAGCACGTGGCCACCAACCTGGGGCGCAGCCG TGCCTGGCTGTACCTGGCCCTCAACGAGAACTCCTTGGAGAGCTACCTGCGGTTGTTCCAGGAGAACCTGGGCCTGCTGCATAAGTACTA CGTCAAGAATGCCCTGGTCTGCAGCCACGATCACCTGACGCTCTTCCTGACCTTGGTGTCCGGGCTAGAGTTCATTCGTTTCGAGCTGGA TCTGACCTTGGCACCCGCCATCAACTGGTTGCCTTTTCTCAACACCATCTTCTACCCCGTGGAGATCAATGAATCCGAGCCTATTGTGGT CTATGACAAGGAATACCTTGAGCAGATCTCCACTCTCATCAACACCACCGACAGATGCCTGCTCAACAACTACATGATCTGGAACCTGGT GCGGAAAACAAGCTCCTTCCTTGACCAGCGCTTTCAGGACGCCGATGAGAAGTTCATGGAAGTCATGTACGGGACCAAGAAGACCTGTCT TCCTCGCTGGAAGTTTTGCGTGAGTGACACAGAAAACAACCTGGGCTTTGCGTTGGGCCCCATGTTTGTCAAAGCAACCTTCGCCGAGGA CAGCAAGAGCATAGCCACCGAGATCATCCTGGAGATTAAGAAGGCATTTGAGGAAAGCCTGAGCACCCTGAAGTGGATGGATGAGGAAAC CCGAAAATCAGCCAAGGAAAAGGCCGATGCCATCTACAACATGATAGGATACCCCAACTTCATCATGGATCCCAAGGAGCTGGACAAAGT GTTTAATGACTACACTGCAGTTCCAGACCTCTACTTTGAAAATGCCATGCGGTTTTTCAACTTCTCATGGAGGGTCACTGCCGATCAGCT CAGGAAAGCCCCCAACAGAGATCAGTGGAGCATGACCCCGCCCATGGTGAACGCCTACTACTCGCCCACCAAGAATGAGATTGTGTTTCC GGCCGGGATCCTGCAGGCACCATTCTACACACGCTCCTCACCCAAGGCCTTAAACTTTGGTGGCATAGGTGTCGTCGTGGGCCATGAGCT GACTCATGCTTTTGATGATCAAGGACGGGAGTATGACAAGGACGGGAACCTCCGGCCATGGTGGAAGAACTCATCCGTGGAGGCCTTCAA GCGTCAGACCGAGTGCATGGTAGAGCAGTACAGCAACTACAGCGTGAACGGGGAGCCGGTGAACGGGCGGCACACCCTGGGGGAGAACAT CGCCGACAACGGGGGTCTCAAGGCGGCCTATCGGGCTTACCAGAACTGGGTGAAGAAGAACGGGGCTGAGCACTCGCTCCCCACCCTGGG CCTCACCAATAACCAGCTCTTCTTCCTGGGCTTTGCACAGGTCTGGTGCTCCGTCCGCACACCTGAGAGCTCCCACGAAGGCCTCATCAC CGATCCCCACAGCCCCTCTCGCTTCCGGGTCATCGGCTCCCTCTCCAATTCCAAGGAGTTCTCAGAACACTTCCGCTGCCCACCTGGCTC ACCCATGAACCCGCCTCACAAGTGCGAAGTCTGGTAAGGACGAAGCGGAGAGAGCCAAGACGGAGGAGGGGAAGGGGCTGAGGACGAGAC CCCCATCCAGCCTCCAGGGCATTGCTCAGCCCGCTTGGCCACCCGGGGCCCTGCTTCCTCACACTGGCGGGTTTTCAGCCGGAACCGAGC CCATGGTGTTGGCTCTCAACGTGACCCGCAGTCTGATCCCCTGTGAAGAGCCGGACATCCCAGGCACACGTGTGCGCCACCTTCAGCAGG CATTCGGGTGCTGGGCTGGTGGCTCATCAGGCCTGGGCCCCACACTGACAAGCGCCAGATACGCCACAAATACCACTGTGTCAAATGCTT TCAAGATATATTTTTGGGGAAACTATTTTTTAAACACTGTGGAATACACTGGAAATCTTCAGGGAAAAACACATTTAAACACTTTTTTTT TTAAGGAAAGAATTGGTATATTTATTATGTTCTGTTTTTCTAAATAACCTGTGGACAAGGGAAGCCCCACTGATTTACTCCCTCTCTTCC CCACTCCCTGTGAGGCTGGGCTGAGGCACGGATCCCTGGGCCACAGAGCAAGTCTCCAAATCAGACAGCTGCCTCAGCCCCTGGGATGTG TGATTTCAGCTCCTGTCACCTCATGCAAGGGCGTGGAGACCAGTAGAGGTGTGGAGGCCAGGCAGAGAGAGGAGCCTGCTCTGCGGGGGG CCCAGCTCATGGGCACTGCCCCTTCAGCTAGCCTGCCTCCGTCCCCTGAGTCCAACAGTGGGAGCCCTAGCTGGGAAGTTCTGATCCCCA AAGCCACAGCAGGGGACTGATGGCTATAGCAGAATGAGGTCGGGTCAGGACCCTCAAACACCATCTGGGAACACCAAGCACCCTGAATCG AGACTGCAGGAGCCCTGCGGGGTGAGACTGTGTCAGAGATACACTGCTGGCCACAAGTGTCCCCTCTCAGTCCCACCTTTTCGGGCTGTC CCATGTCTATCTCAGGGGCCCGTTACCTCTCTGCAGCAGTCCCCCATCCCAGCCACACCAGGGTCTGTCCGGCCAACCCTCTTCCCCAGG GAAAGGAGAAAAGAGAAAACAGGCTGGGCCCGGTGGCTCACTCCTGTAATCCCAGCACTTTGGGAGGTTGAGGTGGGCGGATCACCTGAG GTCAGGAGTTTGAGACCAGCCTGGCCAACGTGGTGAAACCCCATCTCTACTAAAAAAAATTACAAAAATTAGCCGGGAGTGGTGGTGGGC ACCTGTAATCCCAGTTACTCGGGAGGCTGAGGCAAGAGAATCTCTTGAGCTCAGGAGGCAGAGGTTGCAGTGAGCTGAGATTGCGCCACT >In-frame_PLEKHM2_ENST00000375793_chr1_16045120_+_ECE1_ENST00000374893_chr1_21573856_-_2023nt AGGCGAGGCGAGGGCCGGGCGGCGGGCGCCGGGCCCCGCGGCCGGCACGACGGAGCCCCCGTACGGCCGGCGGCAGCGGTTGGCGGCGGC CCCCGGCCCCCGGCGCGGGAAGCGGCGGCGGGGCGGCGGCGGCGGTGGCGGTGGCGGTGGCGGCGACGGTGGCAGCGCCATGGAGCCGGG GGAGGTGAAGGACCGGATCCTGGAGAACATCTCGCTGTCGGTGAAGAAGTTGCAGAGCTATTTTGCTGCATGTGAGGATGAGATCCCTGC CATCCGGAACCATGACAAGGTCCTACAGCGTCTGTGTGAGCACCTGGACCACGCCCTGCTGTACGGACTGCAAGACCTCTCCTCTGGCTA CTGGGTGCTCGTGGTGCATTTTACTCGGAGAGAGGCCATCAAGCAGATCGAGGTGCTGCAGCACGTGGCCACCAACCTGGGGCGCAGCCG TGCCTGGCTGTACCTGGCCCTCAACGAGAACTCCTTGGAGAGCTACCTGCGGTTGTTCCAGGAGAACCTGGGCCTGCTGCATAAGTACTA CGTCAAGAATGCCCTGGTCTGCAGCCACGATCACCTGACGCTCTTCCTGACCTTGGTGTCCGGGCTAGAGTTCATTCGTTTCGAGCTGGA TCTGACCTTGGCACCCGCCATCAACTGGTTGCCTTTTCTCAACACCATCTTCTACCCCGTGGAGATCAATGAATCCGAGCCTATTGTGGT CTATGACAAGGAATACCTTGAGCAGATCTCCACTCTCATCAACACCACCGACAGATGCCTGCTCAACAACTACATGATCTGGAACCTGGT GCGGAAAACAAGCTCCTTCCTTGACCAGCGCTTTCAGGACGCCGATGAGAAGTTCATGGAAGTCATGTACGGGACCAAGAAGACCTGTCT TCCTCGCTGGAAGTTTTGCGTGAGTGACACAGAAAACAACCTGGGCTTTGCGTTGGGCCCCATGTTTGTCAAAGCAACCTTCGCCGAGGA CAGCAAGAGCATAGCCACCGAGATCATCCTGGAGATTAAGAAGGCATTTGAGGAAAGCCTGAGCACCCTGAAGTGGATGGATGAGGAAAC CCGAAAATCAGCCAAGGAAAAGGCCGATGCCATCTACAACATGATAGGATACCCCAACTTCATCATGGATCCCAAGGAGCTGGACAAAGT GTTTAATGACTACACTGCAGTTCCAGACCTCTACTTTGAAAATGCCATGCGGTTTTTCAACTTCTCATGGAGGGTCACTGCCGATCAGCT CAGGAAAGCCCCCAACAGAGATCAGTGGAGCATGACCCCGCCCATGGTGAACGCCTACTACTCGCCCACCAAGAATGAGATTGTGTTTCC GGCCGGGATCCTGCAGGCACCATTCTACACACGCTCCTCACCCAAGGCCTTAAACTTTGGTGGCATAGGTGTCGTCGTGGGCCATGAGCT GACTCATGCTTTTGATGATCAAGGACGGGAGTATGACAAGGACGGGAACCTCCGGCCATGGTGGAAGAACTCATCCGTGGAGGCCTTCAA GCGTCAGACCGAGTGCATGGTAGAGCAGTACAGCAACTACAGCGTGAACGGGGAGCCGGTGAACGGGCGGCACACCCTGGGGGAGAACAT CGCCGACAACGGGGGTCTCAAGGCGGCCTATCGGGCTTACCAGAACTGGGTGAAGAAGAACGGGGCTGAGCACTCGCTCCCCACCCTGGG CCTCACCAATAACCAGCTCTTCTTCCTGGGCTTTGCACAGGTCTGGTGCTCCGTCCGCACACCTGAGAGCTCCCACGAAGGCCTCATCAC CGATCCCCACAGCCCCTCTCGCTTCCGGGTCATCGGCTCCCTCTCCAATTCCAAGGAGTTCTCAGAACACTTCCGCTGCCCACCTGGCTC ACCCATGAACCCGCCTCACAAGTGCGAAGTCTGGTAAGGACGAAGCGGAGAGAGCCAAGACGGAGGAGGGGAAGGGGCTGAGGACGAGAC >In-frame_PLEKHM2_ENST00000375793_chr1_16045120_+_ECE1_ENST00000436918_chr1_21573856_-_1892nt AGGCGAGGCGAGGGCCGGGCGGCGGGCGCCGGGCCCCGCGGCCGGCACGACGGAGCCCCCGTACGGCCGGCGGCAGCGGTTGGCGGCGGC CCCCGGCCCCCGGCGCGGGAAGCGGCGGCGGGGCGGCGGCGGCGGTGGCGGTGGCGGTGGCGGCGACGGTGGCAGCGCCATGGAGCCGGG GGAGGTGAAGGACCGGATCCTGGAGAACATCTCGCTGTCGGTGAAGAAGTTGCAGAGCTATTTTGCTGCATGTGAGGATGAGATCCCTGC CATCCGGAACCATGACAAGGTCCTACAGCGTCTGTGTGAGCACCTGGACCACGCCCTGCTGTACGGACTGCAAGACCTCTCCTCTGGCTA CTGGGTGCTCGTGGTGCATTTTACTCGGAGAGAGGCCATCAAGCAGATCGAGGTGCTGCAGCACGTGGCCACCAACCTGGGGCGCAGCCG TGCCTGGCTGTACCTGGCCCTCAACGAGAACTCCTTGGAGAGCTACCTGCGGTTGTTCCAGGAGAACCTGGGCCTGCTGCATAAGTACTA CGTCAAGAATGCCCTGGTCTGCAGCCACGATCACCTGACGCTCTTCCTGACCTTGGTGTCCGGGCTAGAGTTCATTCGTTTCGAGCTGGA TCTGACCTTGGCACCCGCCATCAACTGGTTGCCTTTTCTCAACACCATCTTCTACCCCGTGGAGATCAATGAATCCGAGCCTATTGTGGT CTATGACAAGGAATACCTTGAGCAGATCTCCACTCTCATCAACACCACCGACAGATGCCTGCTCAACAACTACATGATCTGGAACCTGGT GCGGAAAACAAGCTCCTTCCTTGACCAGCGCTTTCAGGACGCCGATGAGAAGTTCATGGAAGTCATGTACGGGACCAAGAAGACCTGTCT TCCTCGCTGGAAGTTTTGCGTGAGTGACACAGAAAACAACCTGGGCTTTGCGTTGGGCCCCATGTTTGTCAAAGCAACCTTCGCCGAGGA CAGCAAGAGCATAGCCACCGAGATCATCCTGGAGATTAAGAAGGCATTTGAGGAAAGCCTGAGCACCCTGAAGTGGATGGATGAGGAAAC CCGAAAATCAGCCAAGGAAAAGGCCGATGCCATCTACAACATGATAGGATACCCCAACTTCATCATGGATCCCAAGGAGCTGGACAAAGT GTTTAATGACTACACTGCAGTTCCAGACCTCTACTTTGAAAATGCCATGCGGTTTTTCAACTTCTCATGGAGGGTCACTGCCGATCAGCT CAGGAAAGCCCCCAACAGAGATCAGTGGAGCATGACCCCGCCCATGGTGAACGCCTACTACTCGCCCACCAAGAATGAGATTGTGTTTCC GGCCGGGATCCTGCAGGCACCATTCTACACACGCTCCTCACCCAAGGCCTTAAACTTTGGTGGCATAGGTGTCGTCGTGGGCCATGAGCT GACTCATGCTTTTGATGATCAAGGACGGGAGTATGACAAGGACGGGAACCTCCGGCCATGGTGGAAGAACTCATCCGTGGAGGCCTTCAA GCGTCAGACCGAGTGCATGGTAGAGCAGTACAGCAACTACAGCGTGAACGGGGAGCCGGTGAACGGGCGGCACACCCTGGGGGAGAACAT CGCCGACAACGGGGGTCTCAAGGCGGCCTATCGGGTCTGGTGCTCCGTCCGCACACCTGAGAGCTCCCACGAAGGCCTCATCACCGATCC CCACAGCCCCTCTCGCTTCCGGGTCATCGGCTCCCTCTCCAATTCCAAGGAGTTCTCAGAACACTTCCGCTGCCCACCTGGCTCACCCAT GAACCCGCCTCACAAGTGCGAAGTCTGGTAAGGACGAAGCGGAGAGAGCCAAGACGGAGGAGGGGAAGGGGCTGAGGACGAGACCCCCAT >In-frame_PLEKHM2_ENST00000375793_chr1_16045120_+_ECE1_ENST00000264205_chr1_21573856_-_1945nt AGGCGAGGCGAGGGCCGGGCGGCGGGCGCCGGGCCCCGCGGCCGGCACGACGGAGCCCCCGTACGGCCGGCGGCAGCGGTTGGCGGCGGC CCCCGGCCCCCGGCGCGGGAAGCGGCGGCGGGGCGGCGGCGGCGGTGGCGGTGGCGGTGGCGGCGACGGTGGCAGCGCCATGGAGCCGGG GGAGGTGAAGGACCGGATCCTGGAGAACATCTCGCTGTCGGTGAAGAAGTTGCAGAGCTATTTTGCTGCATGTGAGGATGAGATCCCTGC CATCCGGAACCATGACAAGGTCCTACAGCGTCTGTGTGAGCACCTGGACCACGCCCTGCTGTACGGACTGCAAGACCTCTCCTCTGGCTA CTGGGTGCTCGTGGTGCATTTTACTCGGAGAGAGGCCATCAAGCAGATCGAGGTGCTGCAGCACGTGGCCACCAACCTGGGGCGCAGCCG TGCCTGGCTGTACCTGGCCCTCAACGAGAACTCCTTGGAGAGCTACCTGCGGTTGTTCCAGGAGAACCTGGGCCTGCTGCATAAGTACTA CGTCAAGAATGCCCTGGTCTGCAGCCACGATCACCTGACGCTCTTCCTGACCTTGGTGTCCGGGCTAGAGTTCATTCGTTTCGAGCTGGA TCTGACCTTGGCACCCGCCATCAACTGGTTGCCTTTTCTCAACACCATCTTCTACCCCGTGGAGATCAATGAATCCGAGCCTATTGTGGT CTATGACAAGGAATACCTTGAGCAGATCTCCACTCTCATCAACACCACCGACAGATGCCTGCTCAACAACTACATGATCTGGAACCTGGT GCGGAAAACAAGCTCCTTCCTTGACCAGCGCTTTCAGGACGCCGATGAGAAGTTCATGGAAGTCATGTACGGGACCAAGAAGACCTGTCT TCCTCGCTGGAAGTTTTGCGTGAGTGACACAGAAAACAACCTGGGCTTTGCGTTGGGCCCCATGTTTGTCAAAGCAACCTTCGCCGAGGA CAGCAAGAGCATAGCCACCGAGATCATCCTGGAGATTAAGAAGGCATTTGAGGAAAGCCTGAGCACCCTGAAGTGGATGGATGAGGAAAC CCGAAAATCAGCCAAGGAAAAGGCCGATGCCATCTACAACATGATAGGATACCCCAACTTCATCATGGATCCCAAGGAGCTGGACAAAGT GTTTAATGACTACACTGCAGTTCCAGACCTCTACTTTGAAAATGCCATGCGGTTTTTCAACTTCTCATGGAGGGTCACTGCCGATCAGCT CAGGAAAGCCCCCAACAGAGATCAGTGGAGCATGACCCCGCCCATGGTGAACGCCTACTACTCGCCCACCAAGAATGAGATTGTGTTTCC GGCCGGGATCCTGCAGGCACCATTCTACACACGCTCCTCACCCAAGGCCTTAAACTTTGGTGGCATAGGTGTCGTCGTGGGCCATGAGCT GACTCATGCTTTTGATGATCAAGGACGGGAGTATGACAAGGACGGGAACCTCCGGCCATGGTGGAAGAACTCATCCGTGGAGGCCTTCAA GCGTCAGACCGAGTGCATGGTAGAGCAGTACAGCAACTACAGCGTGAACGGGGAGCCGGTGAACGGGCGGCACACCCTGGGGGAGAACAT CGCCGACAACGGGGGTCTCAAGGCGGCCTATCGGGCTTACCAGAACTGGGTGAAGAAGAACGGGGCTGAGCACTCGCTCCCCACCCTGGG CCTCACCAATAACCAGCTCTTCTTCCTGGGCTTTGCACAGGTCTGGTGCTCCGTCCGCACACCTGAGAGCTCCCACGAAGGCCTCATCAC CGATCCCCACAGCCCCTCTCGCTTCCGGGTCATCGGCTCCCTCTCCAATTCCAAGGAGTTCTCAGAACACTTCCGCTGCCCACCTGGCTC |
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FusionGenePPI for PLEKHM2_ECE1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| PLEKHM2 | CBR1, POLR2F, OFD1 | ECE1 | MYOC, SSR4, LAMTOR2, RPS26, RPSA, DNAJC5, DBN1, FKBP10, RPL19, FAF2, VMA21, CALCA, AGT, KNG1, FBXO6, CLK2, KRTAP10-1, KRTAP10-5, PTPRK, LGALS3, CLK1, LGALS9, LGALS8, NPB, FUT3, SUSD4, C7orf69, MTNR1A |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | PLEKHM2 | chr1:16045120 | chr1:21573856 | ENST00000375799 | + | 5 | 20 | 1_310 | 155 | 1020 | KIF5B |
| Hgene | PLEKHM2 | chr1:16045120 | chr1:21573856 | ENST00000375799 | + | 5 | 20 | 762_885 | 155 | 1020 | sifA |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for PLEKHM2_ECE1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for PLEKHM2_ECE1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | ECE1 | C0018798 | Congenital Heart Defects | 2 | CTD_human |
| Tgene | ECE1 | C0011860 | Diabetes Mellitus, Non-Insulin-Dependent | 1 | CTD_human |
| Tgene | ECE1 | C0019569 | Hirschsprung Disease | 1 | CTD_human;HPO;ORPHANET |
| Tgene | ECE1 | C0020538 | Hypertensive disease | 1 | CTD_human |
| Tgene | ECE1 | C0376634 | Craniofacial Abnormalities | 1 | CTD_human |
| Tgene | ECE1 | C1145628 | Autonomic nervous system disorders | 1 | CTD_human;HPO |
| Tgene | ECE1 | C3151237 | Hirschsprung Disease, Cardiac Defects, and Autonomic Dysfunction | 1 | UNIPROT |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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