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Fusion gene ID: 27509 |
FusionGeneSummary for PLCG1_EYA2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PLCG1_EYA2 | Fusion gene ID: 27509 | Hgene | Tgene | Gene symbol | PLCG1 | EYA2 | Gene ID | 5335 | 2139 |
| Gene name | phospholipase C gamma 1 | EYA transcriptional coactivator and phosphatase 2 | |
| Synonyms | NCKAP3|PLC-II|PLC1|PLC148|PLCgamma1 | EAB1 | |
| Cytomap | 20q12 | 20q13.12 | |
| Type of gene | protein-coding | protein-coding | |
| Description | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-11-phosphatidyl-D-myo-inositol-4,5-bisphosphatePLC-148PLC-gamma-1inositoltrisphosphohydrolasemonophosphatidylinositol phosphodiesterasephosphatidylinositol phospholipase Cphosphoinosit | eyes absent homolog 2 | |
| Modification date | 20180522 | 20180523 | |
| UniProtAcc | P19174 | O00167 | |
| Ensembl transtripts involved in fusion gene | ENST00000244007, ENST00000373272, ENST00000373271, ENST00000608689, | ENST00000357410, ENST00000327619, ENST00000497428, ENST00000317304, | |
| Fusion gene scores | * DoF score | 4 X 3 X 3=36 | 11 X 7 X 8=616 |
| # samples | 4 | 16 | |
| ** MAII score | log2(4/36*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(16/616*10)=-1.94485844580754 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: PLCG1 [Title/Abstract] AND EYA2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Oncogene involved fusion gene, in-frame and retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | PLCG1 | GO:0043536 | positive regulation of blood vessel endothelial cell migration | 20011604 |
| Hgene | PLCG1 | GO:0045766 | positive regulation of angiogenesis | 20011604 |
| Hgene | PLCG1 | GO:0071364 | cellular response to epidermal growth factor stimulus | 17229814 |
| Tgene | EYA2 | GO:0016576 | histone dephosphorylation | 19351884 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | STAD | TCGA-VQ-A8PH-01A | PLCG1 | chr20 | 39798909 | + | EYA2 | chr20 | 45797787 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000244007 | ENST00000357410 | PLCG1 | chr20 | 39798909 | + | EYA2 | chr20 | 45797787 | + |
| In-frame | ENST00000244007 | ENST00000327619 | PLCG1 | chr20 | 39798909 | + | EYA2 | chr20 | 45797787 | + |
| 5CDS-intron | ENST00000244007 | ENST00000497428 | PLCG1 | chr20 | 39798909 | + | EYA2 | chr20 | 45797787 | + |
| 5CDS-intron | ENST00000244007 | ENST00000317304 | PLCG1 | chr20 | 39798909 | + | EYA2 | chr20 | 45797787 | + |
| In-frame | ENST00000373272 | ENST00000357410 | PLCG1 | chr20 | 39798909 | + | EYA2 | chr20 | 45797787 | + |
| In-frame | ENST00000373272 | ENST00000327619 | PLCG1 | chr20 | 39798909 | + | EYA2 | chr20 | 45797787 | + |
| 5CDS-intron | ENST00000373272 | ENST00000497428 | PLCG1 | chr20 | 39798909 | + | EYA2 | chr20 | 45797787 | + |
| 5CDS-intron | ENST00000373272 | ENST00000317304 | PLCG1 | chr20 | 39798909 | + | EYA2 | chr20 | 45797787 | + |
| In-frame | ENST00000373271 | ENST00000357410 | PLCG1 | chr20 | 39798909 | + | EYA2 | chr20 | 45797787 | + |
| In-frame | ENST00000373271 | ENST00000327619 | PLCG1 | chr20 | 39798909 | + | EYA2 | chr20 | 45797787 | + |
| 5CDS-intron | ENST00000373271 | ENST00000497428 | PLCG1 | chr20 | 39798909 | + | EYA2 | chr20 | 45797787 | + |
| 5CDS-intron | ENST00000373271 | ENST00000317304 | PLCG1 | chr20 | 39798909 | + | EYA2 | chr20 | 45797787 | + |
| intron-3CDS | ENST00000608689 | ENST00000357410 | PLCG1 | chr20 | 39798909 | + | EYA2 | chr20 | 45797787 | + |
| intron-3CDS | ENST00000608689 | ENST00000327619 | PLCG1 | chr20 | 39798909 | + | EYA2 | chr20 | 45797787 | + |
| intron-intron | ENST00000608689 | ENST00000497428 | PLCG1 | chr20 | 39798909 | + | EYA2 | chr20 | 45797787 | + |
| intron-intron | ENST00000608689 | ENST00000317304 | PLCG1 | chr20 | 39798909 | + | EYA2 | chr20 | 45797787 | + |
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FusionProtFeatures for PLCG1_EYA2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| PLCG1 | EYA2 |
| Mediates the production of the second messengermolecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate(IP3). Plays an important role in the regulation of intracellularsignaling cascades. Becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, such asPDGFRA, PDGFRB, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role inactin reorganization and cell migration.{ECO:0000269|PubMed:17229814}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | PLCG1 | chr20:39798909 | chr20:45797787 | ENST00000244007 | + | 25 | 33 | 165_176 | 936 | 1292 | Calcium binding | Ontology_term=ECO:0000255 |
| Hgene | PLCG1 | chr20:39798909 | chr20:45797787 | ENST00000373271 | + | 24 | 32 | 165_176 | 936 | 1291 | Calcium binding | Ontology_term=ECO:0000255 |
| Hgene | PLCG1 | chr20:39798909 | chr20:45797787 | ENST00000373272 | + | 24 | 32 | 165_176 | 936 | 1292 | Calcium binding | Ontology_term=ECO:0000255 |
| Hgene | PLCG1 | chr20:39798909 | chr20:45797787 | ENST00000244007 | + | 25 | 33 | 152_187 | 936 | 1292 | Domain | EF-hand |
| Hgene | PLCG1 | chr20:39798909 | chr20:45797787 | ENST00000244007 | + | 25 | 33 | 27_142 | 936 | 1292 | Domain | PH 1 |
| Hgene | PLCG1 | chr20:39798909 | chr20:45797787 | ENST00000244007 | + | 25 | 33 | 320_464 | 936 | 1292 | Domain | PI-PLC X-box |
| Hgene | PLCG1 | chr20:39798909 | chr20:45797787 | ENST00000244007 | + | 25 | 33 | 489_523 | 936 | 1292 | Domain | PH 2%3B first part |
| Hgene | PLCG1 | chr20:39798909 | chr20:45797787 | ENST00000244007 | + | 25 | 33 | 550_657 | 936 | 1292 | Domain | SH2 1 |
| Hgene | PLCG1 | chr20:39798909 | chr20:45797787 | ENST00000244007 | + | 25 | 33 | 668_756 | 936 | 1292 | Domain | SH2 2 |
| Hgene | PLCG1 | chr20:39798909 | chr20:45797787 | ENST00000244007 | + | 25 | 33 | 791_851 | 936 | 1292 | Domain | SH3 |
| Hgene | PLCG1 | chr20:39798909 | chr20:45797787 | ENST00000244007 | + | 25 | 33 | 895_931 | 936 | 1292 | Domain | PH 2%3B second part |
| Hgene | PLCG1 | chr20:39798909 | chr20:45797787 | ENST00000373271 | + | 24 | 32 | 152_187 | 936 | 1291 | Domain | EF-hand |
| Hgene | PLCG1 | chr20:39798909 | chr20:45797787 | ENST00000373271 | + | 24 | 32 | 27_142 | 936 | 1291 | Domain | PH 1 |
| Hgene | PLCG1 | chr20:39798909 | chr20:45797787 | ENST00000373271 | + | 24 | 32 | 320_464 | 936 | 1291 | Domain | PI-PLC X-box |
| Hgene | PLCG1 | chr20:39798909 | chr20:45797787 | ENST00000373271 | + | 24 | 32 | 489_523 | 936 | 1291 | Domain | PH 2%3B first part |
| Hgene | PLCG1 | chr20:39798909 | chr20:45797787 | ENST00000373271 | + | 24 | 32 | 550_657 | 936 | 1291 | Domain | SH2 1 |
| Hgene | PLCG1 | chr20:39798909 | chr20:45797787 | ENST00000373271 | + | 24 | 32 | 668_756 | 936 | 1291 | Domain | SH2 2 |
| Hgene | PLCG1 | chr20:39798909 | chr20:45797787 | ENST00000373271 | + | 24 | 32 | 791_851 | 936 | 1291 | Domain | SH3 |
| Hgene | PLCG1 | chr20:39798909 | chr20:45797787 | ENST00000373271 | + | 24 | 32 | 895_931 | 936 | 1291 | Domain | PH 2%3B second part |
| Hgene | PLCG1 | chr20:39798909 | chr20:45797787 | ENST00000373272 | + | 24 | 32 | 152_187 | 936 | 1292 | Domain | EF-hand |
| Hgene | PLCG1 | chr20:39798909 | chr20:45797787 | ENST00000373272 | + | 24 | 32 | 27_142 | 936 | 1292 | Domain | PH 1 |
| Hgene | PLCG1 | chr20:39798909 | chr20:45797787 | ENST00000373272 | + | 24 | 32 | 320_464 | 936 | 1292 | Domain | PI-PLC X-box |
| Hgene | PLCG1 | chr20:39798909 | chr20:45797787 | ENST00000373272 | + | 24 | 32 | 489_523 | 936 | 1292 | Domain | PH 2%3B first part |
| Hgene | PLCG1 | chr20:39798909 | chr20:45797787 | ENST00000373272 | + | 24 | 32 | 550_657 | 936 | 1292 | Domain | SH2 1 |
| Hgene | PLCG1 | chr20:39798909 | chr20:45797787 | ENST00000373272 | + | 24 | 32 | 668_756 | 936 | 1292 | Domain | SH2 2 |
| Hgene | PLCG1 | chr20:39798909 | chr20:45797787 | ENST00000373272 | + | 24 | 32 | 791_851 | 936 | 1292 | Domain | SH3 |
| Hgene | PLCG1 | chr20:39798909 | chr20:45797787 | ENST00000373272 | + | 24 | 32 | 895_931 | 936 | 1292 | Domain | PH 2%3B second part |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >PLCG1 | chr20:39798909 | chr20:45797787 | ENST00000244007 | + | 25 | 33 | 1075_1177 | 936 | 1292 | Domain | C2 |
| Hgene | >PLCG1 | chr20:39798909 | chr20:45797787 | ENST00000244007 | + | 25 | 33 | 953_1070 | 936 | 1292 | Domain | PI-PLC Y-box |
| Hgene | >PLCG1 | chr20:39798909 | chr20:45797787 | ENST00000373271 | + | 24 | 32 | 1075_1177 | 936 | 1291 | Domain | C2 |
| Hgene | >PLCG1 | chr20:39798909 | chr20:45797787 | ENST00000373271 | + | 24 | 32 | 953_1070 | 936 | 1291 | Domain | PI-PLC Y-box |
| Hgene | >PLCG1 | chr20:39798909 | chr20:45797787 | ENST00000373272 | + | 24 | 32 | 1075_1177 | 936 | 1292 | Domain | C2 |
| Hgene | >PLCG1 | chr20:39798909 | chr20:45797787 | ENST00000373272 | + | 24 | 32 | 953_1070 | 936 | 1292 | Domain | PI-PLC Y-box |
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FusionGeneSequence for PLCG1_EYA2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_PLCG1_ENST00000244007_chr20_39798909_+_EYA2_ENST00000357410_chr20_45797787_+_1070aa MAGAASPCANGCGPGAPSDAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQITWSRGADKIEGAIDIREIKEIRPGKTSRDF DRYQEDPAFRPDQSHCFVILYGMEFRLKTLSLQATSEDEVNMWIKGLTWLMEDTLQAPTPLQIERWLRKQFYSVDRNREDRISAKDLKNM LSQVNYRVPNMRFLRERLTDLEQRSGDITYGQFAQLYRSLMYSAQKTMDLPFLEASTLRAGERPELCRVSLPEFQQFLLDYQGELWAVDR LQVQEFMLSFLRDPLREIEEPYFFLDEFVTFLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMG CRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIAQQRNMAQYFKKVLGDTLLTKPVEISADGLP SPNQLKRKILIKHKKLAEGSAYEEVPTSMMYSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEVSS STELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFD SLYDLITHYQQVPLRCNEFEMRLSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQE GQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQREDEL TFIKSAIIQNVEKQEGGWWRGDYGGKKQLWFPSNYVEEMVNPVALEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNNRLFVFSIS MASVAHWSLDVAADSQEELQDWVKKIREVAQTADARDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKL >In-frame_PLCG1_ENST00000244007_chr20_39798909_+_EYA2_ENST00000327619_chr20_45797787_+_1149aa MAGAASPCANGCGPGAPSDAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQITWSRGADKIEGAIDIREIKEIRPGKTSRDF DRYQEDPAFRPDQSHCFVILYGMEFRLKTLSLQATSEDEVNMWIKGLTWLMEDTLQAPTPLQIERWLRKQFYSVDRNREDRISAKDLKNM LSQVNYRVPNMRFLRERLTDLEQRSGDITYGQFAQLYRSLMYSAQKTMDLPFLEASTLRAGERPELCRVSLPEFQQFLLDYQGELWAVDR LQVQEFMLSFLRDPLREIEEPYFFLDEFVTFLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMG CRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIAQQRNMAQYFKKVLGDTLLTKPVEISADGLP SPNQLKRKILIKHKKLAEGSAYEEVPTSMMYSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEVSS STELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFD SLYDLITHYQQVPLRCNEFEMRLSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQE GQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQREDEL TFIKSAIIQNVEKQEGGWWRGDYGGKKQLWFPSNYVEEMVNPVALEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNNRLFVFSIS MASVAHWSLDVAADSQEELQDWVKKIREVAQTADARDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKL AFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIE >In-frame_PLCG1_ENST00000373272_chr20_39798909_+_EYA2_ENST00000357410_chr20_45797787_+_1070aa MAGAASPCANGCGPGAPSDAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQITWSRGADKIEGAIDIREIKEIRPGKTSRDF DRYQEDPAFRPDQSHCFVILYGMEFRLKTLSLQATSEDEVNMWIKGLTWLMEDTLQAPTPLQIERWLRKQFYSVDRNREDRISAKDLKNM LSQVNYRVPNMRFLRERLTDLEQRSGDITYGQFAQLYRSLMYSAQKTMDLPFLEASTLRAGERPELCRVSLPEFQQFLLDYQGELWAVDR LQVQEFMLSFLRDPLREIEEPYFFLDEFVTFLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMG CRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIAQQRNMAQYFKKVLGDTLLTKPVEISADGLP SPNQLKRKILIKHKKLAEGSAYEEVPTSMMYSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEVSS STELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFD SLYDLITHYQQVPLRCNEFEMRLSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQE GQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQREDEL TFIKSAIIQNVEKQEGGWWRGDYGGKKQLWFPSNYVEEMVNPVALEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNNRLFVFSIS MASVAHWSLDVAADSQEELQDWVKKIREVAQTADARDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKL >In-frame_PLCG1_ENST00000373272_chr20_39798909_+_EYA2_ENST00000327619_chr20_45797787_+_1149aa MAGAASPCANGCGPGAPSDAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQITWSRGADKIEGAIDIREIKEIRPGKTSRDF DRYQEDPAFRPDQSHCFVILYGMEFRLKTLSLQATSEDEVNMWIKGLTWLMEDTLQAPTPLQIERWLRKQFYSVDRNREDRISAKDLKNM LSQVNYRVPNMRFLRERLTDLEQRSGDITYGQFAQLYRSLMYSAQKTMDLPFLEASTLRAGERPELCRVSLPEFQQFLLDYQGELWAVDR LQVQEFMLSFLRDPLREIEEPYFFLDEFVTFLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMG CRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIAQQRNMAQYFKKVLGDTLLTKPVEISADGLP SPNQLKRKILIKHKKLAEGSAYEEVPTSMMYSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEVSS STELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFD SLYDLITHYQQVPLRCNEFEMRLSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQE GQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQREDEL TFIKSAIIQNVEKQEGGWWRGDYGGKKQLWFPSNYVEEMVNPVALEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNNRLFVFSIS MASVAHWSLDVAADSQEELQDWVKKIREVAQTADARDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKL AFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIE >In-frame_PLCG1_ENST00000373271_chr20_39798909_+_EYA2_ENST00000357410_chr20_45797787_+_1070aa MAGAASPCANGCGPGAPSDAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQITWSRGADKIEGAIDIREIKEIRPGKTSRDF DRYQEDPAFRPDQSHCFVILYGMEFRLKTLSLQATSEDEVNMWIKGLTWLMEDTLQAPTPLQIERWLRKQFYSVDRNREDRISAKDLKNM LSQVNYRVPNMRFLRERLTDLEQRSGDITYGQFAQLYRSLMYSAQKTMDLPFLEASTLRAGERPELCRVSLPEFQQFLLDYQGELWAVDR LQVQEFMLSFLRDPLREIEEPYFFLDEFVTFLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMG CRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIAQQRNMAQYFKKVLGDTLLTKPVEISADGLP SPNQLKRKILIKHKKLAEGSAYEEVPTSMMYSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEVSS STELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFD SLYDLITHYQQVPLRCNEFEMRLSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQE GQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQREDEL TFIKSAIIQNVEKQEGGWWRGDYGGKKQLWFPSNYVEEMVNPVALEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNNRLFVFSIS MASVAHWSLDVAADSQEELQDWVKKIREVAQTADARDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKL >In-frame_PLCG1_ENST00000373271_chr20_39798909_+_EYA2_ENST00000327619_chr20_45797787_+_1149aa MAGAASPCANGCGPGAPSDAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQITWSRGADKIEGAIDIREIKEIRPGKTSRDF DRYQEDPAFRPDQSHCFVILYGMEFRLKTLSLQATSEDEVNMWIKGLTWLMEDTLQAPTPLQIERWLRKQFYSVDRNREDRISAKDLKNM LSQVNYRVPNMRFLRERLTDLEQRSGDITYGQFAQLYRSLMYSAQKTMDLPFLEASTLRAGERPELCRVSLPEFQQFLLDYQGELWAVDR LQVQEFMLSFLRDPLREIEEPYFFLDEFVTFLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMG CRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILSIEDHCSIAQQRNMAQYFKKVLGDTLLTKPVEISADGLP SPNQLKRKILIKHKKLAEGSAYEEVPTSMMYSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEVSS STELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFD SLYDLITHYQQVPLRCNEFEMRLSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQE GQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQREDEL TFIKSAIIQNVEKQEGGWWRGDYGGKKQLWFPSNYVEEMVNPVALEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNNRLFVFSIS MASVAHWSLDVAADSQEELQDWVKKIREVAQTADARDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKL AFRYRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVNVLVTTTQLIPALAKVLLYGLGSVFPIE |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_PLCG1_ENST00000244007_chr20_39798909_+_EYA2_ENST00000357410_chr20_45797787_+_3210nt ATGGCGGGCGCCGCGTCCCCTTGCGCCAACGGCTGCGGGCCCGGCGCGCCCTCGGACGCCGAGGTGCTGCACCTCTGCCGCAGCCTCGAG GTGGGCACCGTCATGACTTTGTTCTACTCCAAGAAGTCGCAGCGACCCGAGCGGAAGACCTTCCAGGTCAAGCTGGAGACGCGCCAGATC ACGTGGAGCCGGGGCGCCGACAAGATCGAGGGGGCCATTGACATTCGTGAAATTAAGGAGATCCGCCCAGGGAAGACCTCACGGGACTTT GATCGCTATCAAGAGGACCCAGCTTTCCGGCCGGACCAGTCACATTGCTTTGTCATTCTCTATGGAATGGAATTTCGCCTGAAAACGCTG AGCCTGCAAGCCACATCTGAGGATGAAGTGAACATGTGGATCAAGGGCTTAACTTGGCTGATGGAGGATACATTGCAGGCACCCACACCC CTGCAGATTGAGAGGTGGCTCCGGAAGCAGTTTTACTCAGTGGATCGGAATCGTGAGGATCGTATATCAGCCAAGGACCTGAAGAACATG CTGTCCCAGGTCAACTACCGGGTCCCCAACATGCGCTTCCTCCGAGAGCGGCTGACGGACCTGGAGCAGCGCAGCGGGGACATCACCTAC GGGCAGTTTGCTCAGCTGTACCGCAGCCTCATGTACAGCGCCCAGAAGACGATGGACCTCCCCTTCTTGGAAGCCAGTACTCTGAGGGCT GGGGAGCGGCCGGAGCTTTGCCGAGTGTCCCTTCCTGAGTTCCAGCAGTTCCTTCTTGACTACCAGGGGGAGCTGTGGGCTGTTGATCGC CTCCAGGTGCAGGAGTTCATGCTCAGCTTCCTCCGAGACCCCTTACGAGAGATCGAGGAGCCATACTTCTTCCTGGATGAGTTTGTCACC TTCCTGTTCTCCAAAGAGAACAGTGTGTGGAACTCGCAGCTGGATGCAGTATGCCCGGACACCATGAACAACCCTCTTTCCCACTACTGG ATCTCCTCCTCGCACAACACGTACCTGACCGGGGACCAGTTCTCCAGTGAGTCCTCCTTGGAAGCCTATGCTCGCTGCCTGCGGATGGGC TGTCGCTGCATTGAGTTGGACTGCTGGGACGGCCCGGATGGGATGCCAGTTATTTACCATGGGCACACCCTTACCACCAAGATCAAGTTC TCAGATGTCCTGCACACCATCAAGGAGCATGCCTTTGTGGCCTCAGAGTACCCAGTCATCCTGTCCATTGAGGACCACTGCAGCATTGCC CAGCAGAGAAACATGGCCCAATACTTCAAGAAGGTGCTGGGGGACACACTCCTCACCAAGCCCGTGGAGATCTCTGCCGACGGGCTCCCC TCACCCAACCAGCTTAAGAGGAAGATCCTCATCAAGCACAAGAAGCTGGCTGAGGGCAGTGCCTACGAGGAGGTGCCTACATCCATGATG TACTCTGAGAACGACATCAGCAACTCTATCAAGAATGGCATCCTCTACCTGGAGGACCCTGTGAACCACGAATGGTATCCCCACTACTTT GTTCTGACCAGCAGCAAGATCTACTACTCTGAGGAGACCAGCAGTGACCAGGGCAACGAGGATGAGGAGGAGCCCAAGGAGGTCAGCAGC AGCACAGAGCTGCACTCCAATGAGAAGTGGTTCCATGGGAAGCTAGGGGCAGGGCGTGACGGGCGTCACATCGCTGAGCGCCTGCTTACT GAGTACTGCATCGAGACCGGAGCCCCTGACGGCTCCTTCCTCGTGCGAGAGAGTGAGACCTTCGTGGGCGACTACACGCTCTCTTTCTGG CGGAACGGGAAAGTCCAGCACTGCCGTATCCACTCCCGGCAAGATGCTGGGACCCCCAAGTTCTTCTTGACAGACAACCTCGTCTTTGAC TCCCTCTATGACCTCATCACGCACTACCAGCAGGTGCCCCTGCGCTGTAATGAGTTTGAGATGCGACTTTCAGAGCCTGTCCCACAGACC AACGCCCACGAGAGCAAAGAGTGGTACCACGCGAGCCTGACCAGAGCACAGGCTGAGCACATGCTAATGCGCGTCCCTCGTGATGGGGCC TTCCTGGTGCGGAAGCGGAATGAACCCAACTCATATGCCATCTCTTTCCGGGCTGAGGGCAAGATCAAGCATTGCCGTGTCCAGCAAGAG GGCCAGACAGTGATGCTAGGGAACTCGGAGTTCGACAGCCTTGTTGACCTCATCAGCTACTATGAGAAACACCCGCTATACCGCAAGATG AAGCTGCGCTATCCCATCAACGAGGAGGCACTGGAGAAGATTGGCACAGCTGAGCCTGACTACGGGGCCCTGTATGAGGGACGCAACCCT GGCTTCTATGTAGAGGCAAACCCTATGCCAACTTTCAAGTGTGCAGTCAAAGCCCTCTTTGACTACAAGGCCCAGAGGGAGGACGAGCTG ACCTTCATCAAGAGCGCCATCATCCAGAATGTGGAGAAGCAAGAGGGAGGCTGGTGGCGAGGGGACTACGGAGGGAAGAAGCAGCTGTGG TTCCCATCAAACTACGTGGAAGAGATGGTCAACCCCGTGGCCCTGGAGCCGGAGAGGGAGCACTTGGACGAGAACAGCCCCCTAGGGGAC TTGCTGCGGGGGGTCTTGGATGTGCCGGCTTGTCAGATTGCCATCCGTCCTGAGGGCAAGAACAACCGGCTCTTCGTCTTCTCCATCAGC ATGGCGTCGGTGGCCCACTGGTCCCTGGATGTTGCTGCCGACTCACAGGAGGAGCTGCAGGACTGGGTGAAAAAGATCCGTGAAGTGGCC CAGACAGCAGACGCCAGGGATTGTGACCAGATCCACGTTGATGACGTCTCATCAGATGACAATGGCCAAGATTTAAGCACATACAACTTC TCCGCTGACGGCTTCCACAGTTCGGCCCCAGGAGCCAACCTGTGCCTGGGCTCTGGCGTGCACGGCGGCGTGGACTGGATGAGGAAGCTG GCCTTCCGCTACCGGCGGGTGAAGGAGATGTACAATACCTACAAGAACAACGTTGGTGGGAAGGAGAGCTGCTTCGAGAGGATAATGCAG AGATTCGGCAGAAAAGCTGTCTACGTGGTGATCGGTGATGGTGTGGAAGAGGAGCAAGGAGCGAAAAAGCACAACATGCCTTTCTGGCGG >In-frame_PLCG1_ENST00000244007_chr20_39798909_+_EYA2_ENST00000327619_chr20_45797787_+_3447nt ATGGCGGGCGCCGCGTCCCCTTGCGCCAACGGCTGCGGGCCCGGCGCGCCCTCGGACGCCGAGGTGCTGCACCTCTGCCGCAGCCTCGAG GTGGGCACCGTCATGACTTTGTTCTACTCCAAGAAGTCGCAGCGACCCGAGCGGAAGACCTTCCAGGTCAAGCTGGAGACGCGCCAGATC ACGTGGAGCCGGGGCGCCGACAAGATCGAGGGGGCCATTGACATTCGTGAAATTAAGGAGATCCGCCCAGGGAAGACCTCACGGGACTTT GATCGCTATCAAGAGGACCCAGCTTTCCGGCCGGACCAGTCACATTGCTTTGTCATTCTCTATGGAATGGAATTTCGCCTGAAAACGCTG AGCCTGCAAGCCACATCTGAGGATGAAGTGAACATGTGGATCAAGGGCTTAACTTGGCTGATGGAGGATACATTGCAGGCACCCACACCC CTGCAGATTGAGAGGTGGCTCCGGAAGCAGTTTTACTCAGTGGATCGGAATCGTGAGGATCGTATATCAGCCAAGGACCTGAAGAACATG CTGTCCCAGGTCAACTACCGGGTCCCCAACATGCGCTTCCTCCGAGAGCGGCTGACGGACCTGGAGCAGCGCAGCGGGGACATCACCTAC GGGCAGTTTGCTCAGCTGTACCGCAGCCTCATGTACAGCGCCCAGAAGACGATGGACCTCCCCTTCTTGGAAGCCAGTACTCTGAGGGCT GGGGAGCGGCCGGAGCTTTGCCGAGTGTCCCTTCCTGAGTTCCAGCAGTTCCTTCTTGACTACCAGGGGGAGCTGTGGGCTGTTGATCGC CTCCAGGTGCAGGAGTTCATGCTCAGCTTCCTCCGAGACCCCTTACGAGAGATCGAGGAGCCATACTTCTTCCTGGATGAGTTTGTCACC TTCCTGTTCTCCAAAGAGAACAGTGTGTGGAACTCGCAGCTGGATGCAGTATGCCCGGACACCATGAACAACCCTCTTTCCCACTACTGG ATCTCCTCCTCGCACAACACGTACCTGACCGGGGACCAGTTCTCCAGTGAGTCCTCCTTGGAAGCCTATGCTCGCTGCCTGCGGATGGGC TGTCGCTGCATTGAGTTGGACTGCTGGGACGGCCCGGATGGGATGCCAGTTATTTACCATGGGCACACCCTTACCACCAAGATCAAGTTC TCAGATGTCCTGCACACCATCAAGGAGCATGCCTTTGTGGCCTCAGAGTACCCAGTCATCCTGTCCATTGAGGACCACTGCAGCATTGCC CAGCAGAGAAACATGGCCCAATACTTCAAGAAGGTGCTGGGGGACACACTCCTCACCAAGCCCGTGGAGATCTCTGCCGACGGGCTCCCC TCACCCAACCAGCTTAAGAGGAAGATCCTCATCAAGCACAAGAAGCTGGCTGAGGGCAGTGCCTACGAGGAGGTGCCTACATCCATGATG TACTCTGAGAACGACATCAGCAACTCTATCAAGAATGGCATCCTCTACCTGGAGGACCCTGTGAACCACGAATGGTATCCCCACTACTTT GTTCTGACCAGCAGCAAGATCTACTACTCTGAGGAGACCAGCAGTGACCAGGGCAACGAGGATGAGGAGGAGCCCAAGGAGGTCAGCAGC AGCACAGAGCTGCACTCCAATGAGAAGTGGTTCCATGGGAAGCTAGGGGCAGGGCGTGACGGGCGTCACATCGCTGAGCGCCTGCTTACT GAGTACTGCATCGAGACCGGAGCCCCTGACGGCTCCTTCCTCGTGCGAGAGAGTGAGACCTTCGTGGGCGACTACACGCTCTCTTTCTGG CGGAACGGGAAAGTCCAGCACTGCCGTATCCACTCCCGGCAAGATGCTGGGACCCCCAAGTTCTTCTTGACAGACAACCTCGTCTTTGAC TCCCTCTATGACCTCATCACGCACTACCAGCAGGTGCCCCTGCGCTGTAATGAGTTTGAGATGCGACTTTCAGAGCCTGTCCCACAGACC AACGCCCACGAGAGCAAAGAGTGGTACCACGCGAGCCTGACCAGAGCACAGGCTGAGCACATGCTAATGCGCGTCCCTCGTGATGGGGCC TTCCTGGTGCGGAAGCGGAATGAACCCAACTCATATGCCATCTCTTTCCGGGCTGAGGGCAAGATCAAGCATTGCCGTGTCCAGCAAGAG GGCCAGACAGTGATGCTAGGGAACTCGGAGTTCGACAGCCTTGTTGACCTCATCAGCTACTATGAGAAACACCCGCTATACCGCAAGATG AAGCTGCGCTATCCCATCAACGAGGAGGCACTGGAGAAGATTGGCACAGCTGAGCCTGACTACGGGGCCCTGTATGAGGGACGCAACCCT GGCTTCTATGTAGAGGCAAACCCTATGCCAACTTTCAAGTGTGCAGTCAAAGCCCTCTTTGACTACAAGGCCCAGAGGGAGGACGAGCTG ACCTTCATCAAGAGCGCCATCATCCAGAATGTGGAGAAGCAAGAGGGAGGCTGGTGGCGAGGGGACTACGGAGGGAAGAAGCAGCTGTGG TTCCCATCAAACTACGTGGAAGAGATGGTCAACCCCGTGGCCCTGGAGCCGGAGAGGGAGCACTTGGACGAGAACAGCCCCCTAGGGGAC TTGCTGCGGGGGGTCTTGGATGTGCCGGCTTGTCAGATTGCCATCCGTCCTGAGGGCAAGAACAACCGGCTCTTCGTCTTCTCCATCAGC ATGGCGTCGGTGGCCCACTGGTCCCTGGATGTTGCTGCCGACTCACAGGAGGAGCTGCAGGACTGGGTGAAAAAGATCCGTGAAGTGGCC CAGACAGCAGACGCCAGGGATTGTGACCAGATCCACGTTGATGACGTCTCATCAGATGACAATGGCCAAGATTTAAGCACATACAACTTC TCCGCTGACGGCTTCCACAGTTCGGCCCCAGGAGCCAACCTGTGCCTGGGCTCTGGCGTGCACGGCGGCGTGGACTGGATGAGGAAGCTG GCCTTCCGCTACCGGCGGGTGAAGGAGATGTACAATACCTACAAGAACAACGTTGGTGGGTTGATAGGCACTCCCAAAAGGGAGACCTGG CTACAGCTCCGAGCTGAGCTGGAAGCTCTCACAGACCTCTGGCTGACCCACTCCCTGAAGGCACTAAACCTCATCAACTCCCGGCCCAAC TGTGTCAATGTGCTGGTCACCACCACTCAACTAATTCCTGCCCTGGCCAAAGTCCTGCTATATGGCCTGGGGTCTGTGTTTCCTATTGAG AACATCTACAGTGCAACCAAGACAGGGAAGGAGAGCTGCTTCGAGAGGATAATGCAGAGATTCGGCAGAAAAGCTGTCTACGTGGTGATC GGTGATGGTGTGGAAGAGGAGCAAGGAGCGAAAAAGCACAACATGCCTTTCTGGCGGATATCCTGCCACGCAGACCTGGAGGCACTGAGG >In-frame_PLCG1_ENST00000373272_chr20_39798909_+_EYA2_ENST00000357410_chr20_45797787_+_3210nt ATGGCGGGCGCCGCGTCCCCTTGCGCCAACGGCTGCGGGCCCGGCGCGCCCTCGGACGCCGAGGTGCTGCACCTCTGCCGCAGCCTCGAG GTGGGCACCGTCATGACTTTGTTCTACTCCAAGAAGTCGCAGCGACCCGAGCGGAAGACCTTCCAGGTCAAGCTGGAGACGCGCCAGATC ACGTGGAGCCGGGGCGCCGACAAGATCGAGGGGGCCATTGACATTCGTGAAATTAAGGAGATCCGCCCAGGGAAGACCTCACGGGACTTT GATCGCTATCAAGAGGACCCAGCTTTCCGGCCGGACCAGTCACATTGCTTTGTCATTCTCTATGGAATGGAATTTCGCCTGAAAACGCTG AGCCTGCAAGCCACATCTGAGGATGAAGTGAACATGTGGATCAAGGGCTTAACTTGGCTGATGGAGGATACATTGCAGGCACCCACACCC CTGCAGATTGAGAGGTGGCTCCGGAAGCAGTTTTACTCAGTGGATCGGAATCGTGAGGATCGTATATCAGCCAAGGACCTGAAGAACATG CTGTCCCAGGTCAACTACCGGGTCCCCAACATGCGCTTCCTCCGAGAGCGGCTGACGGACCTGGAGCAGCGCAGCGGGGACATCACCTAC GGGCAGTTTGCTCAGCTGTACCGCAGCCTCATGTACAGCGCCCAGAAGACGATGGACCTCCCCTTCTTGGAAGCCAGTACTCTGAGGGCT GGGGAGCGGCCGGAGCTTTGCCGAGTGTCCCTTCCTGAGTTCCAGCAGTTCCTTCTTGACTACCAGGGGGAGCTGTGGGCTGTTGATCGC CTCCAGGTGCAGGAGTTCATGCTCAGCTTCCTCCGAGACCCCTTACGAGAGATCGAGGAGCCATACTTCTTCCTGGATGAGTTTGTCACC TTCCTGTTCTCCAAAGAGAACAGTGTGTGGAACTCGCAGCTGGATGCAGTATGCCCGGACACCATGAACAACCCTCTTTCCCACTACTGG ATCTCCTCCTCGCACAACACGTACCTGACCGGGGACCAGTTCTCCAGTGAGTCCTCCTTGGAAGCCTATGCTCGCTGCCTGCGGATGGGC TGTCGCTGCATTGAGTTGGACTGCTGGGACGGCCCGGATGGGATGCCAGTTATTTACCATGGGCACACCCTTACCACCAAGATCAAGTTC TCAGATGTCCTGCACACCATCAAGGAGCATGCCTTTGTGGCCTCAGAGTACCCAGTCATCCTGTCCATTGAGGACCACTGCAGCATTGCC CAGCAGAGAAACATGGCCCAATACTTCAAGAAGGTGCTGGGGGACACACTCCTCACCAAGCCCGTGGAGATCTCTGCCGACGGGCTCCCC TCACCCAACCAGCTTAAGAGGAAGATCCTCATCAAGCACAAGAAGCTGGCTGAGGGCAGTGCCTACGAGGAGGTGCCTACATCCATGATG TACTCTGAGAACGACATCAGCAACTCTATCAAGAATGGCATCCTCTACCTGGAGGACCCTGTGAACCACGAATGGTATCCCCACTACTTT GTTCTGACCAGCAGCAAGATCTACTACTCTGAGGAGACCAGCAGTGACCAGGGCAACGAGGATGAGGAGGAGCCCAAGGAGGTCAGCAGC AGCACAGAGCTGCACTCCAATGAGAAGTGGTTCCATGGGAAGCTAGGGGCAGGGCGTGACGGGCGTCACATCGCTGAGCGCCTGCTTACT GAGTACTGCATCGAGACCGGAGCCCCTGACGGCTCCTTCCTCGTGCGAGAGAGTGAGACCTTCGTGGGCGACTACACGCTCTCTTTCTGG CGGAACGGGAAAGTCCAGCACTGCCGTATCCACTCCCGGCAAGATGCTGGGACCCCCAAGTTCTTCTTGACAGACAACCTCGTCTTTGAC TCCCTCTATGACCTCATCACGCACTACCAGCAGGTGCCCCTGCGCTGTAATGAGTTTGAGATGCGACTTTCAGAGCCTGTCCCACAGACC AACGCCCACGAGAGCAAAGAGTGGTACCACGCGAGCCTGACCAGAGCACAGGCTGAGCACATGCTAATGCGCGTCCCTCGTGATGGGGCC TTCCTGGTGCGGAAGCGGAATGAACCCAACTCATATGCCATCTCTTTCCGGGCTGAGGGCAAGATCAAGCATTGCCGTGTCCAGCAAGAG GGCCAGACAGTGATGCTAGGGAACTCGGAGTTCGACAGCCTTGTTGACCTCATCAGCTACTATGAGAAACACCCGCTATACCGCAAGATG AAGCTGCGCTATCCCATCAACGAGGAGGCACTGGAGAAGATTGGCACAGCTGAGCCTGACTACGGGGCCCTGTATGAGGGACGCAACCCT GGCTTCTATGTAGAGGCAAACCCTATGCCAACTTTCAAGTGTGCAGTCAAAGCCCTCTTTGACTACAAGGCCCAGAGGGAGGACGAGCTG ACCTTCATCAAGAGCGCCATCATCCAGAATGTGGAGAAGCAAGAGGGAGGCTGGTGGCGAGGGGACTACGGAGGGAAGAAGCAGCTGTGG TTCCCATCAAACTACGTGGAAGAGATGGTCAACCCCGTGGCCCTGGAGCCGGAGAGGGAGCACTTGGACGAGAACAGCCCCCTAGGGGAC TTGCTGCGGGGGGTCTTGGATGTGCCGGCTTGTCAGATTGCCATCCGTCCTGAGGGCAAGAACAACCGGCTCTTCGTCTTCTCCATCAGC ATGGCGTCGGTGGCCCACTGGTCCCTGGATGTTGCTGCCGACTCACAGGAGGAGCTGCAGGACTGGGTGAAAAAGATCCGTGAAGTGGCC CAGACAGCAGACGCCAGGGATTGTGACCAGATCCACGTTGATGACGTCTCATCAGATGACAATGGCCAAGATTTAAGCACATACAACTTC TCCGCTGACGGCTTCCACAGTTCGGCCCCAGGAGCCAACCTGTGCCTGGGCTCTGGCGTGCACGGCGGCGTGGACTGGATGAGGAAGCTG GCCTTCCGCTACCGGCGGGTGAAGGAGATGTACAATACCTACAAGAACAACGTTGGTGGGAAGGAGAGCTGCTTCGAGAGGATAATGCAG AGATTCGGCAGAAAAGCTGTCTACGTGGTGATCGGTGATGGTGTGGAAGAGGAGCAAGGAGCGAAAAAGCACAACATGCCTTTCTGGCGG >In-frame_PLCG1_ENST00000373272_chr20_39798909_+_EYA2_ENST00000327619_chr20_45797787_+_3447nt ATGGCGGGCGCCGCGTCCCCTTGCGCCAACGGCTGCGGGCCCGGCGCGCCCTCGGACGCCGAGGTGCTGCACCTCTGCCGCAGCCTCGAG GTGGGCACCGTCATGACTTTGTTCTACTCCAAGAAGTCGCAGCGACCCGAGCGGAAGACCTTCCAGGTCAAGCTGGAGACGCGCCAGATC ACGTGGAGCCGGGGCGCCGACAAGATCGAGGGGGCCATTGACATTCGTGAAATTAAGGAGATCCGCCCAGGGAAGACCTCACGGGACTTT GATCGCTATCAAGAGGACCCAGCTTTCCGGCCGGACCAGTCACATTGCTTTGTCATTCTCTATGGAATGGAATTTCGCCTGAAAACGCTG AGCCTGCAAGCCACATCTGAGGATGAAGTGAACATGTGGATCAAGGGCTTAACTTGGCTGATGGAGGATACATTGCAGGCACCCACACCC CTGCAGATTGAGAGGTGGCTCCGGAAGCAGTTTTACTCAGTGGATCGGAATCGTGAGGATCGTATATCAGCCAAGGACCTGAAGAACATG CTGTCCCAGGTCAACTACCGGGTCCCCAACATGCGCTTCCTCCGAGAGCGGCTGACGGACCTGGAGCAGCGCAGCGGGGACATCACCTAC GGGCAGTTTGCTCAGCTGTACCGCAGCCTCATGTACAGCGCCCAGAAGACGATGGACCTCCCCTTCTTGGAAGCCAGTACTCTGAGGGCT GGGGAGCGGCCGGAGCTTTGCCGAGTGTCCCTTCCTGAGTTCCAGCAGTTCCTTCTTGACTACCAGGGGGAGCTGTGGGCTGTTGATCGC CTCCAGGTGCAGGAGTTCATGCTCAGCTTCCTCCGAGACCCCTTACGAGAGATCGAGGAGCCATACTTCTTCCTGGATGAGTTTGTCACC TTCCTGTTCTCCAAAGAGAACAGTGTGTGGAACTCGCAGCTGGATGCAGTATGCCCGGACACCATGAACAACCCTCTTTCCCACTACTGG ATCTCCTCCTCGCACAACACGTACCTGACCGGGGACCAGTTCTCCAGTGAGTCCTCCTTGGAAGCCTATGCTCGCTGCCTGCGGATGGGC TGTCGCTGCATTGAGTTGGACTGCTGGGACGGCCCGGATGGGATGCCAGTTATTTACCATGGGCACACCCTTACCACCAAGATCAAGTTC TCAGATGTCCTGCACACCATCAAGGAGCATGCCTTTGTGGCCTCAGAGTACCCAGTCATCCTGTCCATTGAGGACCACTGCAGCATTGCC CAGCAGAGAAACATGGCCCAATACTTCAAGAAGGTGCTGGGGGACACACTCCTCACCAAGCCCGTGGAGATCTCTGCCGACGGGCTCCCC TCACCCAACCAGCTTAAGAGGAAGATCCTCATCAAGCACAAGAAGCTGGCTGAGGGCAGTGCCTACGAGGAGGTGCCTACATCCATGATG TACTCTGAGAACGACATCAGCAACTCTATCAAGAATGGCATCCTCTACCTGGAGGACCCTGTGAACCACGAATGGTATCCCCACTACTTT GTTCTGACCAGCAGCAAGATCTACTACTCTGAGGAGACCAGCAGTGACCAGGGCAACGAGGATGAGGAGGAGCCCAAGGAGGTCAGCAGC AGCACAGAGCTGCACTCCAATGAGAAGTGGTTCCATGGGAAGCTAGGGGCAGGGCGTGACGGGCGTCACATCGCTGAGCGCCTGCTTACT GAGTACTGCATCGAGACCGGAGCCCCTGACGGCTCCTTCCTCGTGCGAGAGAGTGAGACCTTCGTGGGCGACTACACGCTCTCTTTCTGG CGGAACGGGAAAGTCCAGCACTGCCGTATCCACTCCCGGCAAGATGCTGGGACCCCCAAGTTCTTCTTGACAGACAACCTCGTCTTTGAC TCCCTCTATGACCTCATCACGCACTACCAGCAGGTGCCCCTGCGCTGTAATGAGTTTGAGATGCGACTTTCAGAGCCTGTCCCACAGACC AACGCCCACGAGAGCAAAGAGTGGTACCACGCGAGCCTGACCAGAGCACAGGCTGAGCACATGCTAATGCGCGTCCCTCGTGATGGGGCC TTCCTGGTGCGGAAGCGGAATGAACCCAACTCATATGCCATCTCTTTCCGGGCTGAGGGCAAGATCAAGCATTGCCGTGTCCAGCAAGAG GGCCAGACAGTGATGCTAGGGAACTCGGAGTTCGACAGCCTTGTTGACCTCATCAGCTACTATGAGAAACACCCGCTATACCGCAAGATG AAGCTGCGCTATCCCATCAACGAGGAGGCACTGGAGAAGATTGGCACAGCTGAGCCTGACTACGGGGCCCTGTATGAGGGACGCAACCCT GGCTTCTATGTAGAGGCAAACCCTATGCCAACTTTCAAGTGTGCAGTCAAAGCCCTCTTTGACTACAAGGCCCAGAGGGAGGACGAGCTG ACCTTCATCAAGAGCGCCATCATCCAGAATGTGGAGAAGCAAGAGGGAGGCTGGTGGCGAGGGGACTACGGAGGGAAGAAGCAGCTGTGG TTCCCATCAAACTACGTGGAAGAGATGGTCAACCCCGTGGCCCTGGAGCCGGAGAGGGAGCACTTGGACGAGAACAGCCCCCTAGGGGAC TTGCTGCGGGGGGTCTTGGATGTGCCGGCTTGTCAGATTGCCATCCGTCCTGAGGGCAAGAACAACCGGCTCTTCGTCTTCTCCATCAGC ATGGCGTCGGTGGCCCACTGGTCCCTGGATGTTGCTGCCGACTCACAGGAGGAGCTGCAGGACTGGGTGAAAAAGATCCGTGAAGTGGCC CAGACAGCAGACGCCAGGGATTGTGACCAGATCCACGTTGATGACGTCTCATCAGATGACAATGGCCAAGATTTAAGCACATACAACTTC TCCGCTGACGGCTTCCACAGTTCGGCCCCAGGAGCCAACCTGTGCCTGGGCTCTGGCGTGCACGGCGGCGTGGACTGGATGAGGAAGCTG GCCTTCCGCTACCGGCGGGTGAAGGAGATGTACAATACCTACAAGAACAACGTTGGTGGGTTGATAGGCACTCCCAAAAGGGAGACCTGG CTACAGCTCCGAGCTGAGCTGGAAGCTCTCACAGACCTCTGGCTGACCCACTCCCTGAAGGCACTAAACCTCATCAACTCCCGGCCCAAC TGTGTCAATGTGCTGGTCACCACCACTCAACTAATTCCTGCCCTGGCCAAAGTCCTGCTATATGGCCTGGGGTCTGTGTTTCCTATTGAG AACATCTACAGTGCAACCAAGACAGGGAAGGAGAGCTGCTTCGAGAGGATAATGCAGAGATTCGGCAGAAAAGCTGTCTACGTGGTGATC GGTGATGGTGTGGAAGAGGAGCAAGGAGCGAAAAAGCACAACATGCCTTTCTGGCGGATATCCTGCCACGCAGACCTGGAGGCACTGAGG >In-frame_PLCG1_ENST00000373271_chr20_39798909_+_EYA2_ENST00000357410_chr20_45797787_+_3210nt ATGGCGGGCGCCGCGTCCCCTTGCGCCAACGGCTGCGGGCCCGGCGCGCCCTCGGACGCCGAGGTGCTGCACCTCTGCCGCAGCCTCGAG GTGGGCACCGTCATGACTTTGTTCTACTCCAAGAAGTCGCAGCGACCCGAGCGGAAGACCTTCCAGGTCAAGCTGGAGACGCGCCAGATC ACGTGGAGCCGGGGCGCCGACAAGATCGAGGGGGCCATTGACATTCGTGAAATTAAGGAGATCCGCCCAGGGAAGACCTCACGGGACTTT GATCGCTATCAAGAGGACCCAGCTTTCCGGCCGGACCAGTCACATTGCTTTGTCATTCTCTATGGAATGGAATTTCGCCTGAAAACGCTG AGCCTGCAAGCCACATCTGAGGATGAAGTGAACATGTGGATCAAGGGCTTAACTTGGCTGATGGAGGATACATTGCAGGCACCCACACCC CTGCAGATTGAGAGGTGGCTCCGGAAGCAGTTTTACTCAGTGGATCGGAATCGTGAGGATCGTATATCAGCCAAGGACCTGAAGAACATG CTGTCCCAGGTCAACTACCGGGTCCCCAACATGCGCTTCCTCCGAGAGCGGCTGACGGACCTGGAGCAGCGCAGCGGGGACATCACCTAC GGGCAGTTTGCTCAGCTGTACCGCAGCCTCATGTACAGCGCCCAGAAGACGATGGACCTCCCCTTCTTGGAAGCCAGTACTCTGAGGGCT GGGGAGCGGCCGGAGCTTTGCCGAGTGTCCCTTCCTGAGTTCCAGCAGTTCCTTCTTGACTACCAGGGGGAGCTGTGGGCTGTTGATCGC CTCCAGGTGCAGGAGTTCATGCTCAGCTTCCTCCGAGACCCCTTACGAGAGATCGAGGAGCCATACTTCTTCCTGGATGAGTTTGTCACC TTCCTGTTCTCCAAAGAGAACAGTGTGTGGAACTCGCAGCTGGATGCAGTATGCCCGGACACCATGAACAACCCTCTTTCCCACTACTGG ATCTCCTCCTCGCACAACACGTACCTGACCGGGGACCAGTTCTCCAGTGAGTCCTCCTTGGAAGCCTATGCTCGCTGCCTGCGGATGGGC TGTCGCTGCATTGAGTTGGACTGCTGGGACGGCCCGGATGGGATGCCAGTTATTTACCATGGGCACACCCTTACCACCAAGATCAAGTTC TCAGATGTCCTGCACACCATCAAGGAGCATGCCTTTGTGGCCTCAGAGTACCCAGTCATCCTGTCCATTGAGGACCACTGCAGCATTGCC CAGCAGAGAAACATGGCCCAATACTTCAAGAAGGTGCTGGGGGACACACTCCTCACCAAGCCCGTGGAGATCTCTGCCGACGGGCTCCCC TCACCCAACCAGCTTAAGAGGAAGATCCTCATCAAGCACAAGAAGCTGGCTGAGGGCAGTGCCTACGAGGAGGTGCCTACATCCATGATG TACTCTGAGAACGACATCAGCAACTCTATCAAGAATGGCATCCTCTACCTGGAGGACCCTGTGAACCACGAATGGTATCCCCACTACTTT GTTCTGACCAGCAGCAAGATCTACTACTCTGAGGAGACCAGCAGTGACCAGGGCAACGAGGATGAGGAGGAGCCCAAGGAGGTCAGCAGC AGCACAGAGCTGCACTCCAATGAGAAGTGGTTCCATGGGAAGCTAGGGGCAGGGCGTGACGGGCGTCACATCGCTGAGCGCCTGCTTACT GAGTACTGCATCGAGACCGGAGCCCCTGACGGCTCCTTCCTCGTGCGAGAGAGTGAGACCTTCGTGGGCGACTACACGCTCTCTTTCTGG CGGAACGGGAAAGTCCAGCACTGCCGTATCCACTCCCGGCAAGATGCTGGGACCCCCAAGTTCTTCTTGACAGACAACCTCGTCTTTGAC TCCCTCTATGACCTCATCACGCACTACCAGCAGGTGCCCCTGCGCTGTAATGAGTTTGAGATGCGACTTTCAGAGCCTGTCCCACAGACC AACGCCCACGAGAGCAAAGAGTGGTACCACGCGAGCCTGACCAGAGCACAGGCTGAGCACATGCTAATGCGCGTCCCTCGTGATGGGGCC TTCCTGGTGCGGAAGCGGAATGAACCCAACTCATATGCCATCTCTTTCCGGGCTGAGGGCAAGATCAAGCATTGCCGTGTCCAGCAAGAG GGCCAGACAGTGATGCTAGGGAACTCGGAGTTCGACAGCCTTGTTGACCTCATCAGCTACTATGAGAAACACCCGCTATACCGCAAGATG AAGCTGCGCTATCCCATCAACGAGGAGGCACTGGAGAAGATTGGCACAGCTGAGCCTGACTACGGGGCCCTGTATGAGGGACGCAACCCT GGCTTCTATGTAGAGGCAAACCCTATGCCAACTTTCAAGTGTGCAGTCAAAGCCCTCTTTGACTACAAGGCCCAGAGGGAGGACGAGCTG ACCTTCATCAAGAGCGCCATCATCCAGAATGTGGAGAAGCAAGAGGGAGGCTGGTGGCGAGGGGACTACGGAGGGAAGAAGCAGCTGTGG TTCCCATCAAACTACGTGGAAGAGATGGTCAACCCCGTGGCCCTGGAGCCGGAGAGGGAGCACTTGGACGAGAACAGCCCCCTAGGGGAC TTGCTGCGGGGGGTCTTGGATGTGCCGGCTTGTCAGATTGCCATCCGTCCTGAGGGCAAGAACAACCGGCTCTTCGTCTTCTCCATCAGC ATGGCGTCGGTGGCCCACTGGTCCCTGGATGTTGCTGCCGACTCACAGGAGGAGCTGCAGGACTGGGTGAAAAAGATCCGTGAAGTGGCC CAGACAGCAGACGCCAGGGATTGTGACCAGATCCACGTTGATGACGTCTCATCAGATGACAATGGCCAAGATTTAAGCACATACAACTTC TCCGCTGACGGCTTCCACAGTTCGGCCCCAGGAGCCAACCTGTGCCTGGGCTCTGGCGTGCACGGCGGCGTGGACTGGATGAGGAAGCTG GCCTTCCGCTACCGGCGGGTGAAGGAGATGTACAATACCTACAAGAACAACGTTGGTGGGAAGGAGAGCTGCTTCGAGAGGATAATGCAG AGATTCGGCAGAAAAGCTGTCTACGTGGTGATCGGTGATGGTGTGGAAGAGGAGCAAGGAGCGAAAAAGCACAACATGCCTTTCTGGCGG >In-frame_PLCG1_ENST00000373271_chr20_39798909_+_EYA2_ENST00000327619_chr20_45797787_+_3447nt ATGGCGGGCGCCGCGTCCCCTTGCGCCAACGGCTGCGGGCCCGGCGCGCCCTCGGACGCCGAGGTGCTGCACCTCTGCCGCAGCCTCGAG GTGGGCACCGTCATGACTTTGTTCTACTCCAAGAAGTCGCAGCGACCCGAGCGGAAGACCTTCCAGGTCAAGCTGGAGACGCGCCAGATC ACGTGGAGCCGGGGCGCCGACAAGATCGAGGGGGCCATTGACATTCGTGAAATTAAGGAGATCCGCCCAGGGAAGACCTCACGGGACTTT GATCGCTATCAAGAGGACCCAGCTTTCCGGCCGGACCAGTCACATTGCTTTGTCATTCTCTATGGAATGGAATTTCGCCTGAAAACGCTG AGCCTGCAAGCCACATCTGAGGATGAAGTGAACATGTGGATCAAGGGCTTAACTTGGCTGATGGAGGATACATTGCAGGCACCCACACCC CTGCAGATTGAGAGGTGGCTCCGGAAGCAGTTTTACTCAGTGGATCGGAATCGTGAGGATCGTATATCAGCCAAGGACCTGAAGAACATG CTGTCCCAGGTCAACTACCGGGTCCCCAACATGCGCTTCCTCCGAGAGCGGCTGACGGACCTGGAGCAGCGCAGCGGGGACATCACCTAC GGGCAGTTTGCTCAGCTGTACCGCAGCCTCATGTACAGCGCCCAGAAGACGATGGACCTCCCCTTCTTGGAAGCCAGTACTCTGAGGGCT GGGGAGCGGCCGGAGCTTTGCCGAGTGTCCCTTCCTGAGTTCCAGCAGTTCCTTCTTGACTACCAGGGGGAGCTGTGGGCTGTTGATCGC CTCCAGGTGCAGGAGTTCATGCTCAGCTTCCTCCGAGACCCCTTACGAGAGATCGAGGAGCCATACTTCTTCCTGGATGAGTTTGTCACC TTCCTGTTCTCCAAAGAGAACAGTGTGTGGAACTCGCAGCTGGATGCAGTATGCCCGGACACCATGAACAACCCTCTTTCCCACTACTGG ATCTCCTCCTCGCACAACACGTACCTGACCGGGGACCAGTTCTCCAGTGAGTCCTCCTTGGAAGCCTATGCTCGCTGCCTGCGGATGGGC TGTCGCTGCATTGAGTTGGACTGCTGGGACGGCCCGGATGGGATGCCAGTTATTTACCATGGGCACACCCTTACCACCAAGATCAAGTTC TCAGATGTCCTGCACACCATCAAGGAGCATGCCTTTGTGGCCTCAGAGTACCCAGTCATCCTGTCCATTGAGGACCACTGCAGCATTGCC CAGCAGAGAAACATGGCCCAATACTTCAAGAAGGTGCTGGGGGACACACTCCTCACCAAGCCCGTGGAGATCTCTGCCGACGGGCTCCCC TCACCCAACCAGCTTAAGAGGAAGATCCTCATCAAGCACAAGAAGCTGGCTGAGGGCAGTGCCTACGAGGAGGTGCCTACATCCATGATG TACTCTGAGAACGACATCAGCAACTCTATCAAGAATGGCATCCTCTACCTGGAGGACCCTGTGAACCACGAATGGTATCCCCACTACTTT GTTCTGACCAGCAGCAAGATCTACTACTCTGAGGAGACCAGCAGTGACCAGGGCAACGAGGATGAGGAGGAGCCCAAGGAGGTCAGCAGC AGCACAGAGCTGCACTCCAATGAGAAGTGGTTCCATGGGAAGCTAGGGGCAGGGCGTGACGGGCGTCACATCGCTGAGCGCCTGCTTACT GAGTACTGCATCGAGACCGGAGCCCCTGACGGCTCCTTCCTCGTGCGAGAGAGTGAGACCTTCGTGGGCGACTACACGCTCTCTTTCTGG CGGAACGGGAAAGTCCAGCACTGCCGTATCCACTCCCGGCAAGATGCTGGGACCCCCAAGTTCTTCTTGACAGACAACCTCGTCTTTGAC TCCCTCTATGACCTCATCACGCACTACCAGCAGGTGCCCCTGCGCTGTAATGAGTTTGAGATGCGACTTTCAGAGCCTGTCCCACAGACC AACGCCCACGAGAGCAAAGAGTGGTACCACGCGAGCCTGACCAGAGCACAGGCTGAGCACATGCTAATGCGCGTCCCTCGTGATGGGGCC TTCCTGGTGCGGAAGCGGAATGAACCCAACTCATATGCCATCTCTTTCCGGGCTGAGGGCAAGATCAAGCATTGCCGTGTCCAGCAAGAG GGCCAGACAGTGATGCTAGGGAACTCGGAGTTCGACAGCCTTGTTGACCTCATCAGCTACTATGAGAAACACCCGCTATACCGCAAGATG AAGCTGCGCTATCCCATCAACGAGGAGGCACTGGAGAAGATTGGCACAGCTGAGCCTGACTACGGGGCCCTGTATGAGGGACGCAACCCT GGCTTCTATGTAGAGGCAAACCCTATGCCAACTTTCAAGTGTGCAGTCAAAGCCCTCTTTGACTACAAGGCCCAGAGGGAGGACGAGCTG ACCTTCATCAAGAGCGCCATCATCCAGAATGTGGAGAAGCAAGAGGGAGGCTGGTGGCGAGGGGACTACGGAGGGAAGAAGCAGCTGTGG TTCCCATCAAACTACGTGGAAGAGATGGTCAACCCCGTGGCCCTGGAGCCGGAGAGGGAGCACTTGGACGAGAACAGCCCCCTAGGGGAC TTGCTGCGGGGGGTCTTGGATGTGCCGGCTTGTCAGATTGCCATCCGTCCTGAGGGCAAGAACAACCGGCTCTTCGTCTTCTCCATCAGC ATGGCGTCGGTGGCCCACTGGTCCCTGGATGTTGCTGCCGACTCACAGGAGGAGCTGCAGGACTGGGTGAAAAAGATCCGTGAAGTGGCC CAGACAGCAGACGCCAGGGATTGTGACCAGATCCACGTTGATGACGTCTCATCAGATGACAATGGCCAAGATTTAAGCACATACAACTTC TCCGCTGACGGCTTCCACAGTTCGGCCCCAGGAGCCAACCTGTGCCTGGGCTCTGGCGTGCACGGCGGCGTGGACTGGATGAGGAAGCTG GCCTTCCGCTACCGGCGGGTGAAGGAGATGTACAATACCTACAAGAACAACGTTGGTGGGTTGATAGGCACTCCCAAAAGGGAGACCTGG CTACAGCTCCGAGCTGAGCTGGAAGCTCTCACAGACCTCTGGCTGACCCACTCCCTGAAGGCACTAAACCTCATCAACTCCCGGCCCAAC TGTGTCAATGTGCTGGTCACCACCACTCAACTAATTCCTGCCCTGGCCAAAGTCCTGCTATATGGCCTGGGGTCTGTGTTTCCTATTGAG AACATCTACAGTGCAACCAAGACAGGGAAGGAGAGCTGCTTCGAGAGGATAATGCAGAGATTCGGCAGAAAAGCTGTCTACGTGGTGATC GGTGATGGTGTGGAAGAGGAGCAAGGAGCGAAAAAGCACAACATGCCTTTCTGGCGGATATCCTGCCACGCAGACCTGGAGGCACTGAGG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_PLCG1_ENST00000244007_chr20_39798909_+_EYA2_ENST00000357410_chr20_45797787_+_4118nt GAGGGCGCGCGGAGGACCCGCCGCCGCCGGTGTGAGGCGGCCCGTCCTGGCTCCCTTGTCCGGGAAGCCCGCCCAGGAGCCGCCGCCGGG TCCCGCTCGTCTGCCGCCTCAGCCTCAGCCCCAACCTCAGCCGCCGCCGTTGCGCTTGCTCCCGGGCGGTCCTGGCCTGTGCCGCCGCCG CCCCCAGCGTCGGAGCCATGGCGGGCGCCGCGTCCCCTTGCGCCAACGGCTGCGGGCCCGGCGCGCCCTCGGACGCCGAGGTGCTGCACC TCTGCCGCAGCCTCGAGGTGGGCACCGTCATGACTTTGTTCTACTCCAAGAAGTCGCAGCGACCCGAGCGGAAGACCTTCCAGGTCAAGC TGGAGACGCGCCAGATCACGTGGAGCCGGGGCGCCGACAAGATCGAGGGGGCCATTGACATTCGTGAAATTAAGGAGATCCGCCCAGGGA AGACCTCACGGGACTTTGATCGCTATCAAGAGGACCCAGCTTTCCGGCCGGACCAGTCACATTGCTTTGTCATTCTCTATGGAATGGAAT TTCGCCTGAAAACGCTGAGCCTGCAAGCCACATCTGAGGATGAAGTGAACATGTGGATCAAGGGCTTAACTTGGCTGATGGAGGATACAT TGCAGGCACCCACACCCCTGCAGATTGAGAGGTGGCTCCGGAAGCAGTTTTACTCAGTGGATCGGAATCGTGAGGATCGTATATCAGCCA AGGACCTGAAGAACATGCTGTCCCAGGTCAACTACCGGGTCCCCAACATGCGCTTCCTCCGAGAGCGGCTGACGGACCTGGAGCAGCGCA GCGGGGACATCACCTACGGGCAGTTTGCTCAGCTGTACCGCAGCCTCATGTACAGCGCCCAGAAGACGATGGACCTCCCCTTCTTGGAAG CCAGTACTCTGAGGGCTGGGGAGCGGCCGGAGCTTTGCCGAGTGTCCCTTCCTGAGTTCCAGCAGTTCCTTCTTGACTACCAGGGGGAGC TGTGGGCTGTTGATCGCCTCCAGGTGCAGGAGTTCATGCTCAGCTTCCTCCGAGACCCCTTACGAGAGATCGAGGAGCCATACTTCTTCC TGGATGAGTTTGTCACCTTCCTGTTCTCCAAAGAGAACAGTGTGTGGAACTCGCAGCTGGATGCAGTATGCCCGGACACCATGAACAACC CTCTTTCCCACTACTGGATCTCCTCCTCGCACAACACGTACCTGACCGGGGACCAGTTCTCCAGTGAGTCCTCCTTGGAAGCCTATGCTC GCTGCCTGCGGATGGGCTGTCGCTGCATTGAGTTGGACTGCTGGGACGGCCCGGATGGGATGCCAGTTATTTACCATGGGCACACCCTTA CCACCAAGATCAAGTTCTCAGATGTCCTGCACACCATCAAGGAGCATGCCTTTGTGGCCTCAGAGTACCCAGTCATCCTGTCCATTGAGG ACCACTGCAGCATTGCCCAGCAGAGAAACATGGCCCAATACTTCAAGAAGGTGCTGGGGGACACACTCCTCACCAAGCCCGTGGAGATCT CTGCCGACGGGCTCCCCTCACCCAACCAGCTTAAGAGGAAGATCCTCATCAAGCACAAGAAGCTGGCTGAGGGCAGTGCCTACGAGGAGG TGCCTACATCCATGATGTACTCTGAGAACGACATCAGCAACTCTATCAAGAATGGCATCCTCTACCTGGAGGACCCTGTGAACCACGAAT GGTATCCCCACTACTTTGTTCTGACCAGCAGCAAGATCTACTACTCTGAGGAGACCAGCAGTGACCAGGGCAACGAGGATGAGGAGGAGC CCAAGGAGGTCAGCAGCAGCACAGAGCTGCACTCCAATGAGAAGTGGTTCCATGGGAAGCTAGGGGCAGGGCGTGACGGGCGTCACATCG CTGAGCGCCTGCTTACTGAGTACTGCATCGAGACCGGAGCCCCTGACGGCTCCTTCCTCGTGCGAGAGAGTGAGACCTTCGTGGGCGACT ACACGCTCTCTTTCTGGCGGAACGGGAAAGTCCAGCACTGCCGTATCCACTCCCGGCAAGATGCTGGGACCCCCAAGTTCTTCTTGACAG ACAACCTCGTCTTTGACTCCCTCTATGACCTCATCACGCACTACCAGCAGGTGCCCCTGCGCTGTAATGAGTTTGAGATGCGACTTTCAG AGCCTGTCCCACAGACCAACGCCCACGAGAGCAAAGAGTGGTACCACGCGAGCCTGACCAGAGCACAGGCTGAGCACATGCTAATGCGCG TCCCTCGTGATGGGGCCTTCCTGGTGCGGAAGCGGAATGAACCCAACTCATATGCCATCTCTTTCCGGGCTGAGGGCAAGATCAAGCATT GCCGTGTCCAGCAAGAGGGCCAGACAGTGATGCTAGGGAACTCGGAGTTCGACAGCCTTGTTGACCTCATCAGCTACTATGAGAAACACC CGCTATACCGCAAGATGAAGCTGCGCTATCCCATCAACGAGGAGGCACTGGAGAAGATTGGCACAGCTGAGCCTGACTACGGGGCCCTGT ATGAGGGACGCAACCCTGGCTTCTATGTAGAGGCAAACCCTATGCCAACTTTCAAGTGTGCAGTCAAAGCCCTCTTTGACTACAAGGCCC AGAGGGAGGACGAGCTGACCTTCATCAAGAGCGCCATCATCCAGAATGTGGAGAAGCAAGAGGGAGGCTGGTGGCGAGGGGACTACGGAG GGAAGAAGCAGCTGTGGTTCCCATCAAACTACGTGGAAGAGATGGTCAACCCCGTGGCCCTGGAGCCGGAGAGGGAGCACTTGGACGAGA ACAGCCCCCTAGGGGACTTGCTGCGGGGGGTCTTGGATGTGCCGGCTTGTCAGATTGCCATCCGTCCTGAGGGCAAGAACAACCGGCTCT TCGTCTTCTCCATCAGCATGGCGTCGGTGGCCCACTGGTCCCTGGATGTTGCTGCCGACTCACAGGAGGAGCTGCAGGACTGGGTGAAAA AGATCCGTGAAGTGGCCCAGACAGCAGACGCCAGGGATTGTGACCAGATCCACGTTGATGACGTCTCATCAGATGACAATGGCCAAGATT TAAGCACATACAACTTCTCCGCTGACGGCTTCCACAGTTCGGCCCCAGGAGCCAACCTGTGCCTGGGCTCTGGCGTGCACGGCGGCGTGG ACTGGATGAGGAAGCTGGCCTTCCGCTACCGGCGGGTGAAGGAGATGTACAATACCTACAAGAACAACGTTGGTGGGAAGGAGAGCTGCT TCGAGAGGATAATGCAGAGATTCGGCAGAAAAGCTGTCTACGTGGTGATCGGTGATGGTGTGGAAGAGGAGCAAGGAGCGAAAAAGCACA ACATGCCTTTCTGGCGGATATCCTGCCACGCAGACCTGGAGGCACTGAGGCACGCCCTGGAGCTGGAGTATTTATAGCAGGATCAGCAGC ATCTCCACCTGCCATCTCACCCTCAGACCCCCTCGCCTTCCCCACCTCCCCACCGAGAACTCCAGAGACCCAGATGTTGGACACCAGGAA GGGGCCCCACAGCCGAGACGACGTGTCCAGTGACCATCTCAGAAGCCGTCCATCAGTCCAAATGGGGGTTCTGAGAAGGAAAGTACCCAA CATTGGCTTCGGAGTATTTGACTTTGGGGAAAAGGGCTGGCTCGGAGTCTAGACTCTTCTGTAAGACTCACAGAACAAAAGCAAGGAATT GCTGATTTGGGGGGTGCCTGGTGATGAGGAGGGGATGGGTTTGTCTTGTCTTCTTTTTAATTTATGGACTAGTCTCATTACTCCGGAATT ATGCTCTTGTACCTGTGTGGCTGGGTTTCTTAGTCGTTGGTTTGGTTTGGTTTTTTGAACTGGTATGTGGGGTGGTTCACAGTTCTAATG TAAGCACTCTATTCTCCAAGTTGTGCTTTGTGGGGACAATCATTCTTTGAACATTAGAGAGGAAGGCAGTTCAAGCTGTTGAAAAGACTA TTGCTTATTTTTGTTTTTAAAGACCTACTTGACGTCATGTGGACAGTGCACGTGCCTTACGCTACATCTTGTTTTCTAGGAAGAGGGGGA >In-frame_PLCG1_ENST00000244007_chr20_39798909_+_EYA2_ENST00000327619_chr20_45797787_+_4355nt GAGGGCGCGCGGAGGACCCGCCGCCGCCGGTGTGAGGCGGCCCGTCCTGGCTCCCTTGTCCGGGAAGCCCGCCCAGGAGCCGCCGCCGGG TCCCGCTCGTCTGCCGCCTCAGCCTCAGCCCCAACCTCAGCCGCCGCCGTTGCGCTTGCTCCCGGGCGGTCCTGGCCTGTGCCGCCGCCG CCCCCAGCGTCGGAGCCATGGCGGGCGCCGCGTCCCCTTGCGCCAACGGCTGCGGGCCCGGCGCGCCCTCGGACGCCGAGGTGCTGCACC TCTGCCGCAGCCTCGAGGTGGGCACCGTCATGACTTTGTTCTACTCCAAGAAGTCGCAGCGACCCGAGCGGAAGACCTTCCAGGTCAAGC TGGAGACGCGCCAGATCACGTGGAGCCGGGGCGCCGACAAGATCGAGGGGGCCATTGACATTCGTGAAATTAAGGAGATCCGCCCAGGGA AGACCTCACGGGACTTTGATCGCTATCAAGAGGACCCAGCTTTCCGGCCGGACCAGTCACATTGCTTTGTCATTCTCTATGGAATGGAAT TTCGCCTGAAAACGCTGAGCCTGCAAGCCACATCTGAGGATGAAGTGAACATGTGGATCAAGGGCTTAACTTGGCTGATGGAGGATACAT TGCAGGCACCCACACCCCTGCAGATTGAGAGGTGGCTCCGGAAGCAGTTTTACTCAGTGGATCGGAATCGTGAGGATCGTATATCAGCCA AGGACCTGAAGAACATGCTGTCCCAGGTCAACTACCGGGTCCCCAACATGCGCTTCCTCCGAGAGCGGCTGACGGACCTGGAGCAGCGCA GCGGGGACATCACCTACGGGCAGTTTGCTCAGCTGTACCGCAGCCTCATGTACAGCGCCCAGAAGACGATGGACCTCCCCTTCTTGGAAG CCAGTACTCTGAGGGCTGGGGAGCGGCCGGAGCTTTGCCGAGTGTCCCTTCCTGAGTTCCAGCAGTTCCTTCTTGACTACCAGGGGGAGC TGTGGGCTGTTGATCGCCTCCAGGTGCAGGAGTTCATGCTCAGCTTCCTCCGAGACCCCTTACGAGAGATCGAGGAGCCATACTTCTTCC TGGATGAGTTTGTCACCTTCCTGTTCTCCAAAGAGAACAGTGTGTGGAACTCGCAGCTGGATGCAGTATGCCCGGACACCATGAACAACC CTCTTTCCCACTACTGGATCTCCTCCTCGCACAACACGTACCTGACCGGGGACCAGTTCTCCAGTGAGTCCTCCTTGGAAGCCTATGCTC GCTGCCTGCGGATGGGCTGTCGCTGCATTGAGTTGGACTGCTGGGACGGCCCGGATGGGATGCCAGTTATTTACCATGGGCACACCCTTA CCACCAAGATCAAGTTCTCAGATGTCCTGCACACCATCAAGGAGCATGCCTTTGTGGCCTCAGAGTACCCAGTCATCCTGTCCATTGAGG ACCACTGCAGCATTGCCCAGCAGAGAAACATGGCCCAATACTTCAAGAAGGTGCTGGGGGACACACTCCTCACCAAGCCCGTGGAGATCT CTGCCGACGGGCTCCCCTCACCCAACCAGCTTAAGAGGAAGATCCTCATCAAGCACAAGAAGCTGGCTGAGGGCAGTGCCTACGAGGAGG TGCCTACATCCATGATGTACTCTGAGAACGACATCAGCAACTCTATCAAGAATGGCATCCTCTACCTGGAGGACCCTGTGAACCACGAAT GGTATCCCCACTACTTTGTTCTGACCAGCAGCAAGATCTACTACTCTGAGGAGACCAGCAGTGACCAGGGCAACGAGGATGAGGAGGAGC CCAAGGAGGTCAGCAGCAGCACAGAGCTGCACTCCAATGAGAAGTGGTTCCATGGGAAGCTAGGGGCAGGGCGTGACGGGCGTCACATCG CTGAGCGCCTGCTTACTGAGTACTGCATCGAGACCGGAGCCCCTGACGGCTCCTTCCTCGTGCGAGAGAGTGAGACCTTCGTGGGCGACT ACACGCTCTCTTTCTGGCGGAACGGGAAAGTCCAGCACTGCCGTATCCACTCCCGGCAAGATGCTGGGACCCCCAAGTTCTTCTTGACAG ACAACCTCGTCTTTGACTCCCTCTATGACCTCATCACGCACTACCAGCAGGTGCCCCTGCGCTGTAATGAGTTTGAGATGCGACTTTCAG AGCCTGTCCCACAGACCAACGCCCACGAGAGCAAAGAGTGGTACCACGCGAGCCTGACCAGAGCACAGGCTGAGCACATGCTAATGCGCG TCCCTCGTGATGGGGCCTTCCTGGTGCGGAAGCGGAATGAACCCAACTCATATGCCATCTCTTTCCGGGCTGAGGGCAAGATCAAGCATT GCCGTGTCCAGCAAGAGGGCCAGACAGTGATGCTAGGGAACTCGGAGTTCGACAGCCTTGTTGACCTCATCAGCTACTATGAGAAACACC CGCTATACCGCAAGATGAAGCTGCGCTATCCCATCAACGAGGAGGCACTGGAGAAGATTGGCACAGCTGAGCCTGACTACGGGGCCCTGT ATGAGGGACGCAACCCTGGCTTCTATGTAGAGGCAAACCCTATGCCAACTTTCAAGTGTGCAGTCAAAGCCCTCTTTGACTACAAGGCCC AGAGGGAGGACGAGCTGACCTTCATCAAGAGCGCCATCATCCAGAATGTGGAGAAGCAAGAGGGAGGCTGGTGGCGAGGGGACTACGGAG GGAAGAAGCAGCTGTGGTTCCCATCAAACTACGTGGAAGAGATGGTCAACCCCGTGGCCCTGGAGCCGGAGAGGGAGCACTTGGACGAGA ACAGCCCCCTAGGGGACTTGCTGCGGGGGGTCTTGGATGTGCCGGCTTGTCAGATTGCCATCCGTCCTGAGGGCAAGAACAACCGGCTCT TCGTCTTCTCCATCAGCATGGCGTCGGTGGCCCACTGGTCCCTGGATGTTGCTGCCGACTCACAGGAGGAGCTGCAGGACTGGGTGAAAA AGATCCGTGAAGTGGCCCAGACAGCAGACGCCAGGGATTGTGACCAGATCCACGTTGATGACGTCTCATCAGATGACAATGGCCAAGATT TAAGCACATACAACTTCTCCGCTGACGGCTTCCACAGTTCGGCCCCAGGAGCCAACCTGTGCCTGGGCTCTGGCGTGCACGGCGGCGTGG ACTGGATGAGGAAGCTGGCCTTCCGCTACCGGCGGGTGAAGGAGATGTACAATACCTACAAGAACAACGTTGGTGGGTTGATAGGCACTC CCAAAAGGGAGACCTGGCTACAGCTCCGAGCTGAGCTGGAAGCTCTCACAGACCTCTGGCTGACCCACTCCCTGAAGGCACTAAACCTCA TCAACTCCCGGCCCAACTGTGTCAATGTGCTGGTCACCACCACTCAACTAATTCCTGCCCTGGCCAAAGTCCTGCTATATGGCCTGGGGT CTGTGTTTCCTATTGAGAACATCTACAGTGCAACCAAGACAGGGAAGGAGAGCTGCTTCGAGAGGATAATGCAGAGATTCGGCAGAAAAG CTGTCTACGTGGTGATCGGTGATGGTGTGGAAGAGGAGCAAGGAGCGAAAAAGCACAACATGCCTTTCTGGCGGATATCCTGCCACGCAG ACCTGGAGGCACTGAGGCACGCCCTGGAGCTGGAGTATTTATAGCAGGATCAGCAGCATCTCCACCTGCCATCTCACCCTCAGACCCCCT CGCCTTCCCCACCTCCCCACCGAGAACTCCAGAGACCCAGATGTTGGACACCAGGAAGGGGCCCCACAGCCGAGACGACGTGTCCAGTGA CCATCTCAGAAGCCGTCCATCAGTCCAAATGGGGGTTCTGAGAAGGAAAGTACCCAACATTGGCTTCGGAGTATTTGACTTTGGGGAAAA GGGCTGGCTCGGAGTCTAGACTCTTCTGTAAGACTCACAGAACAAAAGCAAGGAATTGCTGATTTGGGGGGTGCCTGGTGATGAGGAGGG GATGGGTTTGTCTTGTCTTCTTTTTAATTTATGGACTAGTCTCATTACTCCGGAATTATGCTCTTGTACCTGTGTGGCTGGGTTTCTTAG TCGTTGGTTTGGTTTGGTTTTTTGAACTGGTATGTGGGGTGGTTCACAGTTCTAATGTAAGCACTCTATTCTCCAAGTTGTGCTTTGTGG GGACAATCATTCTTTGAACATTAGAGAGGAAGGCAGTTCAAGCTGTTGAAAAGACTATTGCTTATTTTTGTTTTTAAAGACCTACTTGAC GTCATGTGGACAGTGCACGTGCCTTACGCTACATCTTGTTTTCTAGGAAGAGGGGGATGCTGGGAAGGAATGGGTGCTTTGTGATGGATA >In-frame_PLCG1_ENST00000373272_chr20_39798909_+_EYA2_ENST00000357410_chr20_45797787_+_4326nt GCCGCTCGTGGCCGCCGGGCTGTGTCCGGGGCCGCGTGAGAAAGCTCTGCGGGACTGAGGGCTGGGTGGGTCGACCGGGAACGGCGCGCG CTCCCGCCGCCATCGCGCCTCCGTCCCCGCCTGCGGCCTGTCTGGGGGTCGCGGGGCGCAGGCGCGGCGGGCCGACGGGCGGGGGTCCTC CCCACGGGTGCGCGGGCGCCTTTGTTCCCGGCGCCGAAGCGGGGTGGGGCCTCAGGGCAGCCCCGCCCCGCCGCGCTGAGGCCCCGCCCC GTGTCCGCCTGCAGGAGCCGCCGCCGGGTCCCGCTCGTCTGCCGCCTCAGCCTCAGCCCCAACCTCAGCCGCCGCCGTTGCGCTTGCTCC CGGGCGGTCCTGGCCTGTGCCGCCGCCGCCCCCAGCGTCGGAGCCATGGCGGGCGCCGCGTCCCCTTGCGCCAACGGCTGCGGGCCCGGC GCGCCCTCGGACGCCGAGGTGCTGCACCTCTGCCGCAGCCTCGAGGTGGGCACCGTCATGACTTTGTTCTACTCCAAGAAGTCGCAGCGA CCCGAGCGGAAGACCTTCCAGGTCAAGCTGGAGACGCGCCAGATCACGTGGAGCCGGGGCGCCGACAAGATCGAGGGGGCCATTGACATT CGTGAAATTAAGGAGATCCGCCCAGGGAAGACCTCACGGGACTTTGATCGCTATCAAGAGGACCCAGCTTTCCGGCCGGACCAGTCACAT TGCTTTGTCATTCTCTATGGAATGGAATTTCGCCTGAAAACGCTGAGCCTGCAAGCCACATCTGAGGATGAAGTGAACATGTGGATCAAG GGCTTAACTTGGCTGATGGAGGATACATTGCAGGCACCCACACCCCTGCAGATTGAGAGGTGGCTCCGGAAGCAGTTTTACTCAGTGGAT CGGAATCGTGAGGATCGTATATCAGCCAAGGACCTGAAGAACATGCTGTCCCAGGTCAACTACCGGGTCCCCAACATGCGCTTCCTCCGA GAGCGGCTGACGGACCTGGAGCAGCGCAGCGGGGACATCACCTACGGGCAGTTTGCTCAGCTGTACCGCAGCCTCATGTACAGCGCCCAG AAGACGATGGACCTCCCCTTCTTGGAAGCCAGTACTCTGAGGGCTGGGGAGCGGCCGGAGCTTTGCCGAGTGTCCCTTCCTGAGTTCCAG CAGTTCCTTCTTGACTACCAGGGGGAGCTGTGGGCTGTTGATCGCCTCCAGGTGCAGGAGTTCATGCTCAGCTTCCTCCGAGACCCCTTA CGAGAGATCGAGGAGCCATACTTCTTCCTGGATGAGTTTGTCACCTTCCTGTTCTCCAAAGAGAACAGTGTGTGGAACTCGCAGCTGGAT GCAGTATGCCCGGACACCATGAACAACCCTCTTTCCCACTACTGGATCTCCTCCTCGCACAACACGTACCTGACCGGGGACCAGTTCTCC AGTGAGTCCTCCTTGGAAGCCTATGCTCGCTGCCTGCGGATGGGCTGTCGCTGCATTGAGTTGGACTGCTGGGACGGCCCGGATGGGATG CCAGTTATTTACCATGGGCACACCCTTACCACCAAGATCAAGTTCTCAGATGTCCTGCACACCATCAAGGAGCATGCCTTTGTGGCCTCA GAGTACCCAGTCATCCTGTCCATTGAGGACCACTGCAGCATTGCCCAGCAGAGAAACATGGCCCAATACTTCAAGAAGGTGCTGGGGGAC ACACTCCTCACCAAGCCCGTGGAGATCTCTGCCGACGGGCTCCCCTCACCCAACCAGCTTAAGAGGAAGATCCTCATCAAGCACAAGAAG CTGGCTGAGGGCAGTGCCTACGAGGAGGTGCCTACATCCATGATGTACTCTGAGAACGACATCAGCAACTCTATCAAGAATGGCATCCTC TACCTGGAGGACCCTGTGAACCACGAATGGTATCCCCACTACTTTGTTCTGACCAGCAGCAAGATCTACTACTCTGAGGAGACCAGCAGT GACCAGGGCAACGAGGATGAGGAGGAGCCCAAGGAGGTCAGCAGCAGCACAGAGCTGCACTCCAATGAGAAGTGGTTCCATGGGAAGCTA GGGGCAGGGCGTGACGGGCGTCACATCGCTGAGCGCCTGCTTACTGAGTACTGCATCGAGACCGGAGCCCCTGACGGCTCCTTCCTCGTG CGAGAGAGTGAGACCTTCGTGGGCGACTACACGCTCTCTTTCTGGCGGAACGGGAAAGTCCAGCACTGCCGTATCCACTCCCGGCAAGAT GCTGGGACCCCCAAGTTCTTCTTGACAGACAACCTCGTCTTTGACTCCCTCTATGACCTCATCACGCACTACCAGCAGGTGCCCCTGCGC TGTAATGAGTTTGAGATGCGACTTTCAGAGCCTGTCCCACAGACCAACGCCCACGAGAGCAAAGAGTGGTACCACGCGAGCCTGACCAGA GCACAGGCTGAGCACATGCTAATGCGCGTCCCTCGTGATGGGGCCTTCCTGGTGCGGAAGCGGAATGAACCCAACTCATATGCCATCTCT TTCCGGGCTGAGGGCAAGATCAAGCATTGCCGTGTCCAGCAAGAGGGCCAGACAGTGATGCTAGGGAACTCGGAGTTCGACAGCCTTGTT GACCTCATCAGCTACTATGAGAAACACCCGCTATACCGCAAGATGAAGCTGCGCTATCCCATCAACGAGGAGGCACTGGAGAAGATTGGC ACAGCTGAGCCTGACTACGGGGCCCTGTATGAGGGACGCAACCCTGGCTTCTATGTAGAGGCAAACCCTATGCCAACTTTCAAGTGTGCA GTCAAAGCCCTCTTTGACTACAAGGCCCAGAGGGAGGACGAGCTGACCTTCATCAAGAGCGCCATCATCCAGAATGTGGAGAAGCAAGAG GGAGGCTGGTGGCGAGGGGACTACGGAGGGAAGAAGCAGCTGTGGTTCCCATCAAACTACGTGGAAGAGATGGTCAACCCCGTGGCCCTG GAGCCGGAGAGGGAGCACTTGGACGAGAACAGCCCCCTAGGGGACTTGCTGCGGGGGGTCTTGGATGTGCCGGCTTGTCAGATTGCCATC CGTCCTGAGGGCAAGAACAACCGGCTCTTCGTCTTCTCCATCAGCATGGCGTCGGTGGCCCACTGGTCCCTGGATGTTGCTGCCGACTCA CAGGAGGAGCTGCAGGACTGGGTGAAAAAGATCCGTGAAGTGGCCCAGACAGCAGACGCCAGGGATTGTGACCAGATCCACGTTGATGAC GTCTCATCAGATGACAATGGCCAAGATTTAAGCACATACAACTTCTCCGCTGACGGCTTCCACAGTTCGGCCCCAGGAGCCAACCTGTGC CTGGGCTCTGGCGTGCACGGCGGCGTGGACTGGATGAGGAAGCTGGCCTTCCGCTACCGGCGGGTGAAGGAGATGTACAATACCTACAAG AACAACGTTGGTGGGAAGGAGAGCTGCTTCGAGAGGATAATGCAGAGATTCGGCAGAAAAGCTGTCTACGTGGTGATCGGTGATGGTGTG GAAGAGGAGCAAGGAGCGAAAAAGCACAACATGCCTTTCTGGCGGATATCCTGCCACGCAGACCTGGAGGCACTGAGGCACGCCCTGGAG CTGGAGTATTTATAGCAGGATCAGCAGCATCTCCACCTGCCATCTCACCCTCAGACCCCCTCGCCTTCCCCACCTCCCCACCGAGAACTC CAGAGACCCAGATGTTGGACACCAGGAAGGGGCCCCACAGCCGAGACGACGTGTCCAGTGACCATCTCAGAAGCCGTCCATCAGTCCAAA TGGGGGTTCTGAGAAGGAAAGTACCCAACATTGGCTTCGGAGTATTTGACTTTGGGGAAAAGGGCTGGCTCGGAGTCTAGACTCTTCTGT AAGACTCACAGAACAAAAGCAAGGAATTGCTGATTTGGGGGGTGCCTGGTGATGAGGAGGGGATGGGTTTGTCTTGTCTTCTTTTTAATT TATGGACTAGTCTCATTACTCCGGAATTATGCTCTTGTACCTGTGTGGCTGGGTTTCTTAGTCGTTGGTTTGGTTTGGTTTTTTGAACTG GTATGTGGGGTGGTTCACAGTTCTAATGTAAGCACTCTATTCTCCAAGTTGTGCTTTGTGGGGACAATCATTCTTTGAACATTAGAGAGG AAGGCAGTTCAAGCTGTTGAAAAGACTATTGCTTATTTTTGTTTTTAAAGACCTACTTGACGTCATGTGGACAGTGCACGTGCCTTACGC TACATCTTGTTTTCTAGGAAGAGGGGGATGCTGGGAAGGAATGGGTGCTTTGTGATGGATAAAAGGCATTAAATAAAACCACGTTTACAT >In-frame_PLCG1_ENST00000373272_chr20_39798909_+_EYA2_ENST00000327619_chr20_45797787_+_4563nt GCCGCTCGTGGCCGCCGGGCTGTGTCCGGGGCCGCGTGAGAAAGCTCTGCGGGACTGAGGGCTGGGTGGGTCGACCGGGAACGGCGCGCG CTCCCGCCGCCATCGCGCCTCCGTCCCCGCCTGCGGCCTGTCTGGGGGTCGCGGGGCGCAGGCGCGGCGGGCCGACGGGCGGGGGTCCTC CCCACGGGTGCGCGGGCGCCTTTGTTCCCGGCGCCGAAGCGGGGTGGGGCCTCAGGGCAGCCCCGCCCCGCCGCGCTGAGGCCCCGCCCC GTGTCCGCCTGCAGGAGCCGCCGCCGGGTCCCGCTCGTCTGCCGCCTCAGCCTCAGCCCCAACCTCAGCCGCCGCCGTTGCGCTTGCTCC CGGGCGGTCCTGGCCTGTGCCGCCGCCGCCCCCAGCGTCGGAGCCATGGCGGGCGCCGCGTCCCCTTGCGCCAACGGCTGCGGGCCCGGC GCGCCCTCGGACGCCGAGGTGCTGCACCTCTGCCGCAGCCTCGAGGTGGGCACCGTCATGACTTTGTTCTACTCCAAGAAGTCGCAGCGA CCCGAGCGGAAGACCTTCCAGGTCAAGCTGGAGACGCGCCAGATCACGTGGAGCCGGGGCGCCGACAAGATCGAGGGGGCCATTGACATT CGTGAAATTAAGGAGATCCGCCCAGGGAAGACCTCACGGGACTTTGATCGCTATCAAGAGGACCCAGCTTTCCGGCCGGACCAGTCACAT TGCTTTGTCATTCTCTATGGAATGGAATTTCGCCTGAAAACGCTGAGCCTGCAAGCCACATCTGAGGATGAAGTGAACATGTGGATCAAG GGCTTAACTTGGCTGATGGAGGATACATTGCAGGCACCCACACCCCTGCAGATTGAGAGGTGGCTCCGGAAGCAGTTTTACTCAGTGGAT CGGAATCGTGAGGATCGTATATCAGCCAAGGACCTGAAGAACATGCTGTCCCAGGTCAACTACCGGGTCCCCAACATGCGCTTCCTCCGA GAGCGGCTGACGGACCTGGAGCAGCGCAGCGGGGACATCACCTACGGGCAGTTTGCTCAGCTGTACCGCAGCCTCATGTACAGCGCCCAG AAGACGATGGACCTCCCCTTCTTGGAAGCCAGTACTCTGAGGGCTGGGGAGCGGCCGGAGCTTTGCCGAGTGTCCCTTCCTGAGTTCCAG CAGTTCCTTCTTGACTACCAGGGGGAGCTGTGGGCTGTTGATCGCCTCCAGGTGCAGGAGTTCATGCTCAGCTTCCTCCGAGACCCCTTA CGAGAGATCGAGGAGCCATACTTCTTCCTGGATGAGTTTGTCACCTTCCTGTTCTCCAAAGAGAACAGTGTGTGGAACTCGCAGCTGGAT GCAGTATGCCCGGACACCATGAACAACCCTCTTTCCCACTACTGGATCTCCTCCTCGCACAACACGTACCTGACCGGGGACCAGTTCTCC AGTGAGTCCTCCTTGGAAGCCTATGCTCGCTGCCTGCGGATGGGCTGTCGCTGCATTGAGTTGGACTGCTGGGACGGCCCGGATGGGATG CCAGTTATTTACCATGGGCACACCCTTACCACCAAGATCAAGTTCTCAGATGTCCTGCACACCATCAAGGAGCATGCCTTTGTGGCCTCA GAGTACCCAGTCATCCTGTCCATTGAGGACCACTGCAGCATTGCCCAGCAGAGAAACATGGCCCAATACTTCAAGAAGGTGCTGGGGGAC ACACTCCTCACCAAGCCCGTGGAGATCTCTGCCGACGGGCTCCCCTCACCCAACCAGCTTAAGAGGAAGATCCTCATCAAGCACAAGAAG CTGGCTGAGGGCAGTGCCTACGAGGAGGTGCCTACATCCATGATGTACTCTGAGAACGACATCAGCAACTCTATCAAGAATGGCATCCTC TACCTGGAGGACCCTGTGAACCACGAATGGTATCCCCACTACTTTGTTCTGACCAGCAGCAAGATCTACTACTCTGAGGAGACCAGCAGT GACCAGGGCAACGAGGATGAGGAGGAGCCCAAGGAGGTCAGCAGCAGCACAGAGCTGCACTCCAATGAGAAGTGGTTCCATGGGAAGCTA GGGGCAGGGCGTGACGGGCGTCACATCGCTGAGCGCCTGCTTACTGAGTACTGCATCGAGACCGGAGCCCCTGACGGCTCCTTCCTCGTG CGAGAGAGTGAGACCTTCGTGGGCGACTACACGCTCTCTTTCTGGCGGAACGGGAAAGTCCAGCACTGCCGTATCCACTCCCGGCAAGAT GCTGGGACCCCCAAGTTCTTCTTGACAGACAACCTCGTCTTTGACTCCCTCTATGACCTCATCACGCACTACCAGCAGGTGCCCCTGCGC TGTAATGAGTTTGAGATGCGACTTTCAGAGCCTGTCCCACAGACCAACGCCCACGAGAGCAAAGAGTGGTACCACGCGAGCCTGACCAGA GCACAGGCTGAGCACATGCTAATGCGCGTCCCTCGTGATGGGGCCTTCCTGGTGCGGAAGCGGAATGAACCCAACTCATATGCCATCTCT TTCCGGGCTGAGGGCAAGATCAAGCATTGCCGTGTCCAGCAAGAGGGCCAGACAGTGATGCTAGGGAACTCGGAGTTCGACAGCCTTGTT GACCTCATCAGCTACTATGAGAAACACCCGCTATACCGCAAGATGAAGCTGCGCTATCCCATCAACGAGGAGGCACTGGAGAAGATTGGC ACAGCTGAGCCTGACTACGGGGCCCTGTATGAGGGACGCAACCCTGGCTTCTATGTAGAGGCAAACCCTATGCCAACTTTCAAGTGTGCA GTCAAAGCCCTCTTTGACTACAAGGCCCAGAGGGAGGACGAGCTGACCTTCATCAAGAGCGCCATCATCCAGAATGTGGAGAAGCAAGAG GGAGGCTGGTGGCGAGGGGACTACGGAGGGAAGAAGCAGCTGTGGTTCCCATCAAACTACGTGGAAGAGATGGTCAACCCCGTGGCCCTG GAGCCGGAGAGGGAGCACTTGGACGAGAACAGCCCCCTAGGGGACTTGCTGCGGGGGGTCTTGGATGTGCCGGCTTGTCAGATTGCCATC CGTCCTGAGGGCAAGAACAACCGGCTCTTCGTCTTCTCCATCAGCATGGCGTCGGTGGCCCACTGGTCCCTGGATGTTGCTGCCGACTCA CAGGAGGAGCTGCAGGACTGGGTGAAAAAGATCCGTGAAGTGGCCCAGACAGCAGACGCCAGGGATTGTGACCAGATCCACGTTGATGAC GTCTCATCAGATGACAATGGCCAAGATTTAAGCACATACAACTTCTCCGCTGACGGCTTCCACAGTTCGGCCCCAGGAGCCAACCTGTGC CTGGGCTCTGGCGTGCACGGCGGCGTGGACTGGATGAGGAAGCTGGCCTTCCGCTACCGGCGGGTGAAGGAGATGTACAATACCTACAAG AACAACGTTGGTGGGTTGATAGGCACTCCCAAAAGGGAGACCTGGCTACAGCTCCGAGCTGAGCTGGAAGCTCTCACAGACCTCTGGCTG ACCCACTCCCTGAAGGCACTAAACCTCATCAACTCCCGGCCCAACTGTGTCAATGTGCTGGTCACCACCACTCAACTAATTCCTGCCCTG GCCAAAGTCCTGCTATATGGCCTGGGGTCTGTGTTTCCTATTGAGAACATCTACAGTGCAACCAAGACAGGGAAGGAGAGCTGCTTCGAG AGGATAATGCAGAGATTCGGCAGAAAAGCTGTCTACGTGGTGATCGGTGATGGTGTGGAAGAGGAGCAAGGAGCGAAAAAGCACAACATG CCTTTCTGGCGGATATCCTGCCACGCAGACCTGGAGGCACTGAGGCACGCCCTGGAGCTGGAGTATTTATAGCAGGATCAGCAGCATCTC CACCTGCCATCTCACCCTCAGACCCCCTCGCCTTCCCCACCTCCCCACCGAGAACTCCAGAGACCCAGATGTTGGACACCAGGAAGGGGC CCCACAGCCGAGACGACGTGTCCAGTGACCATCTCAGAAGCCGTCCATCAGTCCAAATGGGGGTTCTGAGAAGGAAAGTACCCAACATTG GCTTCGGAGTATTTGACTTTGGGGAAAAGGGCTGGCTCGGAGTCTAGACTCTTCTGTAAGACTCACAGAACAAAAGCAAGGAATTGCTGA TTTGGGGGGTGCCTGGTGATGAGGAGGGGATGGGTTTGTCTTGTCTTCTTTTTAATTTATGGACTAGTCTCATTACTCCGGAATTATGCT CTTGTACCTGTGTGGCTGGGTTTCTTAGTCGTTGGTTTGGTTTGGTTTTTTGAACTGGTATGTGGGGTGGTTCACAGTTCTAATGTAAGC ACTCTATTCTCCAAGTTGTGCTTTGTGGGGACAATCATTCTTTGAACATTAGAGAGGAAGGCAGTTCAAGCTGTTGAAAAGACTATTGCT TATTTTTGTTTTTAAAGACCTACTTGACGTCATGTGGACAGTGCACGTGCCTTACGCTACATCTTGTTTTCTAGGAAGAGGGGGATGCTG >In-frame_PLCG1_ENST00000373271_chr20_39798909_+_EYA2_ENST00000357410_chr20_45797787_+_4326nt GCCGCTCGTGGCCGCCGGGCTGTGTCCGGGGCCGCGTGAGAAAGCTCTGCGGGACTGAGGGCTGGGTGGGTCGACCGGGAACGGCGCGCG CTCCCGCCGCCATCGCGCCTCCGTCCCCGCCTGCGGCCTGTCTGGGGGTCGCGGGGCGCAGGCGCGGCGGGCCGACGGGCGGGGGTCCTC CCCACGGGTGCGCGGGCGCCTTTGTTCCCGGCGCCGAAGCGGGGTGGGGCCTCAGGGCAGCCCCGCCCCGCCGCGCTGAGGCCCCGCCCC GTGTCCGCCTGCAGGAGCCGCCGCCGGGTCCCGCTCGTCTGCCGCCTCAGCCTCAGCCCCAACCTCAGCCGCCGCCGTTGCGCTTGCTCC CGGGCGGTCCTGGCCTGTGCCGCCGCCGCCCCCAGCGTCGGAGCCATGGCGGGCGCCGCGTCCCCTTGCGCCAACGGCTGCGGGCCCGGC GCGCCCTCGGACGCCGAGGTGCTGCACCTCTGCCGCAGCCTCGAGGTGGGCACCGTCATGACTTTGTTCTACTCCAAGAAGTCGCAGCGA CCCGAGCGGAAGACCTTCCAGGTCAAGCTGGAGACGCGCCAGATCACGTGGAGCCGGGGCGCCGACAAGATCGAGGGGGCCATTGACATT CGTGAAATTAAGGAGATCCGCCCAGGGAAGACCTCACGGGACTTTGATCGCTATCAAGAGGACCCAGCTTTCCGGCCGGACCAGTCACAT TGCTTTGTCATTCTCTATGGAATGGAATTTCGCCTGAAAACGCTGAGCCTGCAAGCCACATCTGAGGATGAAGTGAACATGTGGATCAAG GGCTTAACTTGGCTGATGGAGGATACATTGCAGGCACCCACACCCCTGCAGATTGAGAGGTGGCTCCGGAAGCAGTTTTACTCAGTGGAT CGGAATCGTGAGGATCGTATATCAGCCAAGGACCTGAAGAACATGCTGTCCCAGGTCAACTACCGGGTCCCCAACATGCGCTTCCTCCGA GAGCGGCTGACGGACCTGGAGCAGCGCAGCGGGGACATCACCTACGGGCAGTTTGCTCAGCTGTACCGCAGCCTCATGTACAGCGCCCAG AAGACGATGGACCTCCCCTTCTTGGAAGCCAGTACTCTGAGGGCTGGGGAGCGGCCGGAGCTTTGCCGAGTGTCCCTTCCTGAGTTCCAG CAGTTCCTTCTTGACTACCAGGGGGAGCTGTGGGCTGTTGATCGCCTCCAGGTGCAGGAGTTCATGCTCAGCTTCCTCCGAGACCCCTTA CGAGAGATCGAGGAGCCATACTTCTTCCTGGATGAGTTTGTCACCTTCCTGTTCTCCAAAGAGAACAGTGTGTGGAACTCGCAGCTGGAT GCAGTATGCCCGGACACCATGAACAACCCTCTTTCCCACTACTGGATCTCCTCCTCGCACAACACGTACCTGACCGGGGACCAGTTCTCC AGTGAGTCCTCCTTGGAAGCCTATGCTCGCTGCCTGCGGATGGGCTGTCGCTGCATTGAGTTGGACTGCTGGGACGGCCCGGATGGGATG CCAGTTATTTACCATGGGCACACCCTTACCACCAAGATCAAGTTCTCAGATGTCCTGCACACCATCAAGGAGCATGCCTTTGTGGCCTCA GAGTACCCAGTCATCCTGTCCATTGAGGACCACTGCAGCATTGCCCAGCAGAGAAACATGGCCCAATACTTCAAGAAGGTGCTGGGGGAC ACACTCCTCACCAAGCCCGTGGAGATCTCTGCCGACGGGCTCCCCTCACCCAACCAGCTTAAGAGGAAGATCCTCATCAAGCACAAGAAG CTGGCTGAGGGCAGTGCCTACGAGGAGGTGCCTACATCCATGATGTACTCTGAGAACGACATCAGCAACTCTATCAAGAATGGCATCCTC TACCTGGAGGACCCTGTGAACCACGAATGGTATCCCCACTACTTTGTTCTGACCAGCAGCAAGATCTACTACTCTGAGGAGACCAGCAGT GACCAGGGCAACGAGGATGAGGAGGAGCCCAAGGAGGTCAGCAGCAGCACAGAGCTGCACTCCAATGAGAAGTGGTTCCATGGGAAGCTA GGGGCAGGGCGTGACGGGCGTCACATCGCTGAGCGCCTGCTTACTGAGTACTGCATCGAGACCGGAGCCCCTGACGGCTCCTTCCTCGTG CGAGAGAGTGAGACCTTCGTGGGCGACTACACGCTCTCTTTCTGGCGGAACGGGAAAGTCCAGCACTGCCGTATCCACTCCCGGCAAGAT GCTGGGACCCCCAAGTTCTTCTTGACAGACAACCTCGTCTTTGACTCCCTCTATGACCTCATCACGCACTACCAGCAGGTGCCCCTGCGC TGTAATGAGTTTGAGATGCGACTTTCAGAGCCTGTCCCACAGACCAACGCCCACGAGAGCAAAGAGTGGTACCACGCGAGCCTGACCAGA GCACAGGCTGAGCACATGCTAATGCGCGTCCCTCGTGATGGGGCCTTCCTGGTGCGGAAGCGGAATGAACCCAACTCATATGCCATCTCT TTCCGGGCTGAGGGCAAGATCAAGCATTGCCGTGTCCAGCAAGAGGGCCAGACAGTGATGCTAGGGAACTCGGAGTTCGACAGCCTTGTT GACCTCATCAGCTACTATGAGAAACACCCGCTATACCGCAAGATGAAGCTGCGCTATCCCATCAACGAGGAGGCACTGGAGAAGATTGGC ACAGCTGAGCCTGACTACGGGGCCCTGTATGAGGGACGCAACCCTGGCTTCTATGTAGAGGCAAACCCTATGCCAACTTTCAAGTGTGCA GTCAAAGCCCTCTTTGACTACAAGGCCCAGAGGGAGGACGAGCTGACCTTCATCAAGAGCGCCATCATCCAGAATGTGGAGAAGCAAGAG GGAGGCTGGTGGCGAGGGGACTACGGAGGGAAGAAGCAGCTGTGGTTCCCATCAAACTACGTGGAAGAGATGGTCAACCCCGTGGCCCTG GAGCCGGAGAGGGAGCACTTGGACGAGAACAGCCCCCTAGGGGACTTGCTGCGGGGGGTCTTGGATGTGCCGGCTTGTCAGATTGCCATC CGTCCTGAGGGCAAGAACAACCGGCTCTTCGTCTTCTCCATCAGCATGGCGTCGGTGGCCCACTGGTCCCTGGATGTTGCTGCCGACTCA CAGGAGGAGCTGCAGGACTGGGTGAAAAAGATCCGTGAAGTGGCCCAGACAGCAGACGCCAGGGATTGTGACCAGATCCACGTTGATGAC GTCTCATCAGATGACAATGGCCAAGATTTAAGCACATACAACTTCTCCGCTGACGGCTTCCACAGTTCGGCCCCAGGAGCCAACCTGTGC CTGGGCTCTGGCGTGCACGGCGGCGTGGACTGGATGAGGAAGCTGGCCTTCCGCTACCGGCGGGTGAAGGAGATGTACAATACCTACAAG AACAACGTTGGTGGGAAGGAGAGCTGCTTCGAGAGGATAATGCAGAGATTCGGCAGAAAAGCTGTCTACGTGGTGATCGGTGATGGTGTG GAAGAGGAGCAAGGAGCGAAAAAGCACAACATGCCTTTCTGGCGGATATCCTGCCACGCAGACCTGGAGGCACTGAGGCACGCCCTGGAG CTGGAGTATTTATAGCAGGATCAGCAGCATCTCCACCTGCCATCTCACCCTCAGACCCCCTCGCCTTCCCCACCTCCCCACCGAGAACTC CAGAGACCCAGATGTTGGACACCAGGAAGGGGCCCCACAGCCGAGACGACGTGTCCAGTGACCATCTCAGAAGCCGTCCATCAGTCCAAA TGGGGGTTCTGAGAAGGAAAGTACCCAACATTGGCTTCGGAGTATTTGACTTTGGGGAAAAGGGCTGGCTCGGAGTCTAGACTCTTCTGT AAGACTCACAGAACAAAAGCAAGGAATTGCTGATTTGGGGGGTGCCTGGTGATGAGGAGGGGATGGGTTTGTCTTGTCTTCTTTTTAATT TATGGACTAGTCTCATTACTCCGGAATTATGCTCTTGTACCTGTGTGGCTGGGTTTCTTAGTCGTTGGTTTGGTTTGGTTTTTTGAACTG GTATGTGGGGTGGTTCACAGTTCTAATGTAAGCACTCTATTCTCCAAGTTGTGCTTTGTGGGGACAATCATTCTTTGAACATTAGAGAGG AAGGCAGTTCAAGCTGTTGAAAAGACTATTGCTTATTTTTGTTTTTAAAGACCTACTTGACGTCATGTGGACAGTGCACGTGCCTTACGC TACATCTTGTTTTCTAGGAAGAGGGGGATGCTGGGAAGGAATGGGTGCTTTGTGATGGATAAAAGGCATTAAATAAAACCACGTTTACAT >In-frame_PLCG1_ENST00000373271_chr20_39798909_+_EYA2_ENST00000327619_chr20_45797787_+_4563nt GCCGCTCGTGGCCGCCGGGCTGTGTCCGGGGCCGCGTGAGAAAGCTCTGCGGGACTGAGGGCTGGGTGGGTCGACCGGGAACGGCGCGCG CTCCCGCCGCCATCGCGCCTCCGTCCCCGCCTGCGGCCTGTCTGGGGGTCGCGGGGCGCAGGCGCGGCGGGCCGACGGGCGGGGGTCCTC CCCACGGGTGCGCGGGCGCCTTTGTTCCCGGCGCCGAAGCGGGGTGGGGCCTCAGGGCAGCCCCGCCCCGCCGCGCTGAGGCCCCGCCCC GTGTCCGCCTGCAGGAGCCGCCGCCGGGTCCCGCTCGTCTGCCGCCTCAGCCTCAGCCCCAACCTCAGCCGCCGCCGTTGCGCTTGCTCC CGGGCGGTCCTGGCCTGTGCCGCCGCCGCCCCCAGCGTCGGAGCCATGGCGGGCGCCGCGTCCCCTTGCGCCAACGGCTGCGGGCCCGGC GCGCCCTCGGACGCCGAGGTGCTGCACCTCTGCCGCAGCCTCGAGGTGGGCACCGTCATGACTTTGTTCTACTCCAAGAAGTCGCAGCGA CCCGAGCGGAAGACCTTCCAGGTCAAGCTGGAGACGCGCCAGATCACGTGGAGCCGGGGCGCCGACAAGATCGAGGGGGCCATTGACATT CGTGAAATTAAGGAGATCCGCCCAGGGAAGACCTCACGGGACTTTGATCGCTATCAAGAGGACCCAGCTTTCCGGCCGGACCAGTCACAT TGCTTTGTCATTCTCTATGGAATGGAATTTCGCCTGAAAACGCTGAGCCTGCAAGCCACATCTGAGGATGAAGTGAACATGTGGATCAAG GGCTTAACTTGGCTGATGGAGGATACATTGCAGGCACCCACACCCCTGCAGATTGAGAGGTGGCTCCGGAAGCAGTTTTACTCAGTGGAT CGGAATCGTGAGGATCGTATATCAGCCAAGGACCTGAAGAACATGCTGTCCCAGGTCAACTACCGGGTCCCCAACATGCGCTTCCTCCGA GAGCGGCTGACGGACCTGGAGCAGCGCAGCGGGGACATCACCTACGGGCAGTTTGCTCAGCTGTACCGCAGCCTCATGTACAGCGCCCAG AAGACGATGGACCTCCCCTTCTTGGAAGCCAGTACTCTGAGGGCTGGGGAGCGGCCGGAGCTTTGCCGAGTGTCCCTTCCTGAGTTCCAG CAGTTCCTTCTTGACTACCAGGGGGAGCTGTGGGCTGTTGATCGCCTCCAGGTGCAGGAGTTCATGCTCAGCTTCCTCCGAGACCCCTTA CGAGAGATCGAGGAGCCATACTTCTTCCTGGATGAGTTTGTCACCTTCCTGTTCTCCAAAGAGAACAGTGTGTGGAACTCGCAGCTGGAT GCAGTATGCCCGGACACCATGAACAACCCTCTTTCCCACTACTGGATCTCCTCCTCGCACAACACGTACCTGACCGGGGACCAGTTCTCC AGTGAGTCCTCCTTGGAAGCCTATGCTCGCTGCCTGCGGATGGGCTGTCGCTGCATTGAGTTGGACTGCTGGGACGGCCCGGATGGGATG CCAGTTATTTACCATGGGCACACCCTTACCACCAAGATCAAGTTCTCAGATGTCCTGCACACCATCAAGGAGCATGCCTTTGTGGCCTCA GAGTACCCAGTCATCCTGTCCATTGAGGACCACTGCAGCATTGCCCAGCAGAGAAACATGGCCCAATACTTCAAGAAGGTGCTGGGGGAC ACACTCCTCACCAAGCCCGTGGAGATCTCTGCCGACGGGCTCCCCTCACCCAACCAGCTTAAGAGGAAGATCCTCATCAAGCACAAGAAG CTGGCTGAGGGCAGTGCCTACGAGGAGGTGCCTACATCCATGATGTACTCTGAGAACGACATCAGCAACTCTATCAAGAATGGCATCCTC TACCTGGAGGACCCTGTGAACCACGAATGGTATCCCCACTACTTTGTTCTGACCAGCAGCAAGATCTACTACTCTGAGGAGACCAGCAGT GACCAGGGCAACGAGGATGAGGAGGAGCCCAAGGAGGTCAGCAGCAGCACAGAGCTGCACTCCAATGAGAAGTGGTTCCATGGGAAGCTA GGGGCAGGGCGTGACGGGCGTCACATCGCTGAGCGCCTGCTTACTGAGTACTGCATCGAGACCGGAGCCCCTGACGGCTCCTTCCTCGTG CGAGAGAGTGAGACCTTCGTGGGCGACTACACGCTCTCTTTCTGGCGGAACGGGAAAGTCCAGCACTGCCGTATCCACTCCCGGCAAGAT GCTGGGACCCCCAAGTTCTTCTTGACAGACAACCTCGTCTTTGACTCCCTCTATGACCTCATCACGCACTACCAGCAGGTGCCCCTGCGC TGTAATGAGTTTGAGATGCGACTTTCAGAGCCTGTCCCACAGACCAACGCCCACGAGAGCAAAGAGTGGTACCACGCGAGCCTGACCAGA GCACAGGCTGAGCACATGCTAATGCGCGTCCCTCGTGATGGGGCCTTCCTGGTGCGGAAGCGGAATGAACCCAACTCATATGCCATCTCT TTCCGGGCTGAGGGCAAGATCAAGCATTGCCGTGTCCAGCAAGAGGGCCAGACAGTGATGCTAGGGAACTCGGAGTTCGACAGCCTTGTT GACCTCATCAGCTACTATGAGAAACACCCGCTATACCGCAAGATGAAGCTGCGCTATCCCATCAACGAGGAGGCACTGGAGAAGATTGGC ACAGCTGAGCCTGACTACGGGGCCCTGTATGAGGGACGCAACCCTGGCTTCTATGTAGAGGCAAACCCTATGCCAACTTTCAAGTGTGCA GTCAAAGCCCTCTTTGACTACAAGGCCCAGAGGGAGGACGAGCTGACCTTCATCAAGAGCGCCATCATCCAGAATGTGGAGAAGCAAGAG GGAGGCTGGTGGCGAGGGGACTACGGAGGGAAGAAGCAGCTGTGGTTCCCATCAAACTACGTGGAAGAGATGGTCAACCCCGTGGCCCTG GAGCCGGAGAGGGAGCACTTGGACGAGAACAGCCCCCTAGGGGACTTGCTGCGGGGGGTCTTGGATGTGCCGGCTTGTCAGATTGCCATC CGTCCTGAGGGCAAGAACAACCGGCTCTTCGTCTTCTCCATCAGCATGGCGTCGGTGGCCCACTGGTCCCTGGATGTTGCTGCCGACTCA CAGGAGGAGCTGCAGGACTGGGTGAAAAAGATCCGTGAAGTGGCCCAGACAGCAGACGCCAGGGATTGTGACCAGATCCACGTTGATGAC GTCTCATCAGATGACAATGGCCAAGATTTAAGCACATACAACTTCTCCGCTGACGGCTTCCACAGTTCGGCCCCAGGAGCCAACCTGTGC CTGGGCTCTGGCGTGCACGGCGGCGTGGACTGGATGAGGAAGCTGGCCTTCCGCTACCGGCGGGTGAAGGAGATGTACAATACCTACAAG AACAACGTTGGTGGGTTGATAGGCACTCCCAAAAGGGAGACCTGGCTACAGCTCCGAGCTGAGCTGGAAGCTCTCACAGACCTCTGGCTG ACCCACTCCCTGAAGGCACTAAACCTCATCAACTCCCGGCCCAACTGTGTCAATGTGCTGGTCACCACCACTCAACTAATTCCTGCCCTG GCCAAAGTCCTGCTATATGGCCTGGGGTCTGTGTTTCCTATTGAGAACATCTACAGTGCAACCAAGACAGGGAAGGAGAGCTGCTTCGAG AGGATAATGCAGAGATTCGGCAGAAAAGCTGTCTACGTGGTGATCGGTGATGGTGTGGAAGAGGAGCAAGGAGCGAAAAAGCACAACATG CCTTTCTGGCGGATATCCTGCCACGCAGACCTGGAGGCACTGAGGCACGCCCTGGAGCTGGAGTATTTATAGCAGGATCAGCAGCATCTC CACCTGCCATCTCACCCTCAGACCCCCTCGCCTTCCCCACCTCCCCACCGAGAACTCCAGAGACCCAGATGTTGGACACCAGGAAGGGGC CCCACAGCCGAGACGACGTGTCCAGTGACCATCTCAGAAGCCGTCCATCAGTCCAAATGGGGGTTCTGAGAAGGAAAGTACCCAACATTG GCTTCGGAGTATTTGACTTTGGGGAAAAGGGCTGGCTCGGAGTCTAGACTCTTCTGTAAGACTCACAGAACAAAAGCAAGGAATTGCTGA TTTGGGGGGTGCCTGGTGATGAGGAGGGGATGGGTTTGTCTTGTCTTCTTTTTAATTTATGGACTAGTCTCATTACTCCGGAATTATGCT CTTGTACCTGTGTGGCTGGGTTTCTTAGTCGTTGGTTTGGTTTGGTTTTTTGAACTGGTATGTGGGGTGGTTCACAGTTCTAATGTAAGC ACTCTATTCTCCAAGTTGTGCTTTGTGGGGACAATCATTCTTTGAACATTAGAGAGGAAGGCAGTTCAAGCTGTTGAAAAGACTATTGCT TATTTTTGTTTTTAAAGACCTACTTGACGTCATGTGGACAGTGCACGTGCCTTACGCTACATCTTGTTTTCTAGGAAGAGGGGGATGCTG |
Top |
FusionGenePPI for PLCG1_EYA2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| PLCG1 | EEF1A1, GIT1, SELE, DGKZ, PLD2, SRC, WAS, VAV1, KHDRBS1, GAB1, LCP2, SH3BP2, DOK1, KIT, GRB2, SHC1, NTRK1, RASA1, SYK, SHB, LAT, RHOA, PKN2, ALK, PDGFA, PDGFRB, PAK1, PTK2, PRKD1, ITK, SYNCRIP, FGFR1, ZAP70, PDGFRA, ARHGAP32, NTRK2, NTRK3, LAT2, SH2B3, RET, TRPM7, TNK1, ERBB2, FLT1, KDR, CBL, EGFR, GNB2L1, IRS2, PTPRJ, PICALM, SOS1, PECAM1, CD22, GHR, SOS2, TUB, MST1R, ABL1, GAB2, GSN, BAG3, LTK, PARK2, EPHB2, PLXNB1, PLXNB2, ARHGEF2, CAMK2A, EPOR, BLNK, IBTK, PML, NCAM1, NPM1, SPRY1, NTMT1, INSR, ERBB3, JAK1, JAK2, EHD4, GTF3C4, LIMD1, AASDHPPT, DPP7, RIC8A, RPL38, SARNP, UBR7, WDR61, PYGB, NXF1, AKT1, CAV1, MVB12B, GAS2L1, SNX11, TEKT2, LDLRAD4, CTPS1, MCMBP, NPEPL1, PFKP, RNF40, STRAP, UCHL5, SKIV2L, TIPRL, UNC45A, FGFR2, PLCG2, PTPN6, DOK2, NCKIPSD, CACNB3, KHDRBS2, RAB11A, CCDC120, TTC9B, KCNJ5, LZTS2, ZNF785, HNRNPK | EYA2 | DMRTB1, RBPMS, SIX4, GNAZ, GNAI2, SIX1, MMS19, ZNF609, TRPS1, NCOR2, CGN, ARID1A, ARID1B, KMT2D, BCOR, NCOR1, TFAP2A, GSE1, CEP85, TLE3, RBM20, KDM6A, PRRC2B, TNRC6A, RAVER1, SEC16A, PUM1, HELZ, CIC, CCDC18, SDCCAG3, KIF14, CNOT1, CEP192, LZTS2, AGO2, NBN, BAG3, MIA3, EYA2, THEM6, PHKG2, CGRRF1, TMEM9, PHKB, NPPC, PHKA2, DUSP1, GPX8, FAM3A, NDUFAF3, NDUFAF4, GMPPB, TMCO1, DCD, PHKA1, CYC1, NDUFA9, GNB2, PIGT, CCDC28A, GDAP1, QPCTL, TIMM21, ETFB, SCO1, ACAD9, AKR7A2, DCAF11, NME1, IDE, LOC442497, DNAJB12, GMPPA, C2orf47, OXA1L, PNKD, UQCRFS1P1, VAPB, SIX2, CCDC85C, AATK, ROR2 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for PLCG1_EYA2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for PLCG1_EYA2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | PLCG1 | C0005586 | Bipolar Disorder | 1 | PSYGENET |
| Hgene | PLCG1 | C0018923 | Hemangiosarcoma | 1 | CTD_human |
| Hgene | PLCG1 | C0023493 | Adult T-Cell Lymphoma/Leukemia | 1 | CTD_human |
| Hgene | PLCG1 | C0036920 | Sezary Syndrome | 1 | CTD_human |
| Hgene | PLCG1 | C0079773 | Lymphoma, T-Cell, Cutaneous | 1 | CTD_human |
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