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Fusion gene ID: 27389 |
FusionGeneSummary for PKM_TRPV3 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PKM_TRPV3 | Fusion gene ID: 27389 | Hgene | Tgene | Gene symbol | PKM | TRPV3 | Gene ID | 5315 | 162514 |
| Gene name | pyruvate kinase M1/2 | transient receptor potential cation channel subfamily V member 3 | |
| Synonyms | CTHBP|HEL-S-30|OIP3|PK3|PKM2|TCB|THBP1 | FNEPPK2|OLMS|VRL3 | |
| Cytomap | 15q23 | 17p13.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | pyruvate kinase PKMOIP-3OPA-interacting protein 3PK, muscle typecytosolic thyroid hormone-binding proteinepididymis secretory protein Li 30p58pyruvate kinase 2/3pyruvate kinase isozymes M1/M2pyruvate kinase muscle isozymepyruvate kinase, muscle | transient receptor potential cation channel subfamily V member 3VRL-3vanilloid receptor-like 3vanilloid receptor-related osmotically activated channel protein | |
| Modification date | 20180527 | 20180527 | |
| UniProtAcc | P14618 | Q8NET8 | |
| Ensembl transtripts involved in fusion gene | ENST00000319622, ENST00000565184, ENST00000389093, ENST00000335181, ENST00000568883, ENST00000449901, ENST00000565154, ENST00000568459, | ENST00000301365, ENST00000576742, ENST00000572519, | |
| Fusion gene scores | * DoF score | 17 X 21 X 3=1071 | 1 X 1 X 1=1 |
| # samples | 21 | 1 | |
| ** MAII score | log2(21/1071*10)=-2.35049724708413 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: PKM [Title/Abstract] AND TRPV3 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | PKM | GO:0012501 | programmed cell death | 17308100 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-BH-A18V-01A | PKM | chr15 | 72502014 | - | TRPV3 | chr17 | 3439007 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shit | ENST00000319622 | ENST00000301365 | PKM | chr15 | 72502014 | - | TRPV3 | chr17 | 3439007 | - |
| Frame-shit | ENST00000319622 | ENST00000576742 | PKM | chr15 | 72502014 | - | TRPV3 | chr17 | 3439007 | - |
| Frame-shit | ENST00000319622 | ENST00000572519 | PKM | chr15 | 72502014 | - | TRPV3 | chr17 | 3439007 | - |
| Frame-shit | ENST00000565184 | ENST00000301365 | PKM | chr15 | 72502014 | - | TRPV3 | chr17 | 3439007 | - |
| Frame-shit | ENST00000565184 | ENST00000576742 | PKM | chr15 | 72502014 | - | TRPV3 | chr17 | 3439007 | - |
| Frame-shit | ENST00000565184 | ENST00000572519 | PKM | chr15 | 72502014 | - | TRPV3 | chr17 | 3439007 | - |
| Frame-shit | ENST00000389093 | ENST00000301365 | PKM | chr15 | 72502014 | - | TRPV3 | chr17 | 3439007 | - |
| Frame-shit | ENST00000389093 | ENST00000576742 | PKM | chr15 | 72502014 | - | TRPV3 | chr17 | 3439007 | - |
| Frame-shit | ENST00000389093 | ENST00000572519 | PKM | chr15 | 72502014 | - | TRPV3 | chr17 | 3439007 | - |
| Frame-shit | ENST00000335181 | ENST00000301365 | PKM | chr15 | 72502014 | - | TRPV3 | chr17 | 3439007 | - |
| Frame-shit | ENST00000335181 | ENST00000576742 | PKM | chr15 | 72502014 | - | TRPV3 | chr17 | 3439007 | - |
| Frame-shit | ENST00000335181 | ENST00000572519 | PKM | chr15 | 72502014 | - | TRPV3 | chr17 | 3439007 | - |
| intron-3CDS | ENST00000568883 | ENST00000301365 | PKM | chr15 | 72502014 | - | TRPV3 | chr17 | 3439007 | - |
| intron-3CDS | ENST00000568883 | ENST00000576742 | PKM | chr15 | 72502014 | - | TRPV3 | chr17 | 3439007 | - |
| intron-3CDS | ENST00000568883 | ENST00000572519 | PKM | chr15 | 72502014 | - | TRPV3 | chr17 | 3439007 | - |
| In-frame | ENST00000449901 | ENST00000301365 | PKM | chr15 | 72502014 | - | TRPV3 | chr17 | 3439007 | - |
| In-frame | ENST00000449901 | ENST00000576742 | PKM | chr15 | 72502014 | - | TRPV3 | chr17 | 3439007 | - |
| In-frame | ENST00000449901 | ENST00000572519 | PKM | chr15 | 72502014 | - | TRPV3 | chr17 | 3439007 | - |
| Frame-shit | ENST00000565154 | ENST00000301365 | PKM | chr15 | 72502014 | - | TRPV3 | chr17 | 3439007 | - |
| Frame-shit | ENST00000565154 | ENST00000576742 | PKM | chr15 | 72502014 | - | TRPV3 | chr17 | 3439007 | - |
| Frame-shit | ENST00000565154 | ENST00000572519 | PKM | chr15 | 72502014 | - | TRPV3 | chr17 | 3439007 | - |
| Frame-shit | ENST00000568459 | ENST00000301365 | PKM | chr15 | 72502014 | - | TRPV3 | chr17 | 3439007 | - |
| Frame-shit | ENST00000568459 | ENST00000576742 | PKM | chr15 | 72502014 | - | TRPV3 | chr17 | 3439007 | - |
| Frame-shit | ENST00000568459 | ENST00000572519 | PKM | chr15 | 72502014 | - | TRPV3 | chr17 | 3439007 | - |
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FusionProtFeatures for PKM_TRPV3 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| PKM | TRPV3 |
| Putative receptor-activated non-selective calciumpermeant cation channel. It is activated by innocuous (warm)temperatures and shows an increased response at noxioustemperatures greater than 39 degrees Celsius. Activation exhibitsan outward rectification. May associate with TRPV1 and maymodulate its activity. Is a negative regulator of hair growth andcycling: TRPV3-coupled signaling suppresses keratinocyteproliferation in hair follicles and induces apoptosis andpremature hair follicle regression (catagen).{ECO:0000269|PubMed:12077604, ECO:0000269|PubMed:12077606,ECO:0000269|PubMed:21593771}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for PKM_TRPV3 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_PKM_ENST00000449901_chr15_72502014_-_TRPV3_ENST00000301365_chr17_3439007_-_751aa MSPEAQPQRTKGPQQPCRSPIVKPGLPSFRPSSCTQPWLTHSWSTCAAWTLIHHPSQPGTLASSVPLYHAETIKNVRTATESFASDPILY RPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGQTALNI AIERRQGDIAALLIAAGADVNAHAKGAFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMEHEQTDITSRDSRGNNILHALVTVAEDFK TQNDFVKRMYDMILLRSGNWELETTRNNDGLTPLQLAAKMGKAEILKYILSREIKEKRLRSLSRKFTDWAYGPVSSSLYDLTNVDTTTDN SVLEITVYNTNIDNRHEMLTLEPLHTLLHMKWKKFAKHMFFLSFCFYFFYNITLTLVSYYRPREEEAIPHPLALTHKMGWLQLLGRMFVL IWAMCISVKEGIAIFLLRPSDLQSILSDAWFHFVFFIQAVLVILSVFLYLFAYKEYLACLVLAMALGWANMLYYTRGFQSMGMYSVMIQK VILHDVLKFLFVYIVFLLGFGVALASLIEKCPKDNKDCSSYGSFSDAVLELFKLTIGLGDLNIQQNSKYPILFLFLLITYVILTFVLLLN MLIALMGETVENVSKESERIWRLQRARTILEFEKMLPEWLRSRFRMGELCKVAEDDFRLCLRINEVKWTEWKTHVSFLNEDPGPVRRTAD >In-frame_PKM_ENST00000449901_chr15_72502014_-_TRPV3_ENST00000576742_chr17_3439007_-_750aa MSPEAQPQRTKGPQQPCRSPIVKPGLPSFRPSSCTQPWLTHSWSTCAAWTLIHHPSQPGTLASSVPLYHAETIKNVRTATESFASDPILY RPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGQTALNI AIERRQGDIAALLIAAGADVNAHAKGAFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMEHEQTDITSRDSRGNNILHALVTVAEDFK TQNDFVKRMYDMILLRSGNWELETTRNNDGLTPLQLAAKMGKAEILKYILSREIKEKRLRSLSRKFTDWAYGPVSSSLYDLTNVDTTTDN SVLEITVYNTNIDNRHEMLTLEPLHTLLHMKWKKFAKHMFFLSFCFYFFYNITLTLVSYYRPREEEAIPHPLALTHKMGWLQLLGRMFVL IWAMCISVKEGIAIFLLRPSDLQSILSDAWFHFVFFIQAVLVILSVFLYLFAYKEYLACLVLAMALGWANMLYYTRGFQSMGMYSVMIQK VILHDVLKFLFVYIVFLLGFGVALASLIEKCPKDNKDCSSYGSFSDAVLELFKLTIGLGDLNIQQNSKYPILFLFLLITYVILTFVLLLN MLIALMGETVENVSKESERIWRLQRARTILEFEKMLPEWLRSRFRMGELCKVAEDDFRLCLRINEVKWTEWKTHVSFLNEDPGPVRRTDF >In-frame_PKM_ENST00000449901_chr15_72502014_-_TRPV3_ENST00000572519_chr17_3439007_-_725aa MSPEAQPQRTKGPQQPCRSPIVKPGLPSFRPSSCTQPWLTHSWSTCAAWTLIHHPSQPGTLASSVPLYHAETIKNVRTATESFASDPILY RPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGQTALNI AIERRQGDIAALLIAAGADVNAHAKGAFFNPKYQHEGFYFGETPLALAACTNQPEIVQLLMEHEQTDITSRDSRGNNILHALVTVAEDFK TQNDFVKRMYDMILLRSGNWELETTRNNDGLTPLQLAAKMGKAEILKYILSREIKEKRLRSLSRKFTDWAYGPVSSSLYDLTNVDTTTDN SVLEITVYNTNIDNRHEMLTLEPLHTLLHMKWKKFAKHMFFLSFCFYFFYNITLTLVSYYRPREEEAIPHPLALTHKMGWLQLLGRMFVL IWAMCISVKEGIAIFLLRPSDLQSILSDAWFHFVFFIQAVLVILSVFLYLFAYKEYLACLVLAMALGWANMLYYTRGFQSMGMYSVMIQK VILHDVLKFLFVYIVFLLGFGVALASLIEKCPKDNKDCSSYGSFSDAVLELFKLTIGLGDLNIQQNSKYPILFLFLLITYVILTFVLLLN MLIALMGETVENVSKESERIWRLQRARTILEFEKMLPEWLRSRFRMGELCKVAEDDFRLCLRINEVKWTEWKTHVSFLNEDPGPVRRTGT |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_PKM_ENST00000449901_chr15_72502014_-_TRPV3_ENST00000301365_chr17_3439007_-_2253nt ATGTCACCGGAAGCCCAACCCCAGAGAACCAAAGGACCTCAGCAGCCATGTCGAAGCCCCATAGTGAAGCCGGGACTGCCTTCATTCAGA CCCAGCAGCTGCACGCAGCCATGGCTGACACATTCCTGGAGCACATGTGCCGCCTGGACATTGATTCACCACCCATCACAGCCCGGAACA CTGGCATCATCTGTACCATTGTACCATGCGGAGACCATCAAGAATGTGCGCACAGCCACGGAAAGCTTTGCTTCTGACCCCATCCTCTAC CGGCCCGTTGCTGTGGCTCTAGACACTAAAGGACCTGAGATCCGAACTGGGCTCATCAAGGGCAGCGGCACTGCAGAGGTGGAGCTGAAG AAGGGAGCCACTCTCAAAATCACGCTGGATAACGCCTACATGGAAAAGTGTGACGAGAACATCCTGTGGCTGGACTACAAGAACATCTGC AAGGTGGTGGAAGTGGGCAGCAAGATCTACGTGGATGATGGGCTTATTTCTCTCCAGGTGAAGCAGAAAGGGCAGACGGCGCTGAACATC GCCATCGAGCGGCGGCAGGGGGACATCGCAGCCCTGCTCATCGCCGCCGGCGCCGACGTCAACGCGCACGCCAAGGGGGCCTTCTTCAAC CCCAAGTACCAACACGAAGGCTTCTACTTCGGTGAGACGCCCCTGGCCCTGGCAGCATGCACCAACCAGCCCGAGATTGTGCAGCTGCTG ATGGAGCACGAGCAGACGGACATCACCTCGCGGGACTCACGAGGCAACAACATCCTTCACGCCCTGGTGACCGTGGCCGAGGACTTCAAG ACGCAGAATGACTTTGTGAAGCGCATGTACGACATGATCCTACTGCGGAGTGGCAACTGGGAGCTGGAGACCACTCGCAACAACGATGGC CTCACGCCGCTGCAGCTGGCCGCCAAGATGGGCAAGGCGGAGATCCTGAAGTACATCCTCAGTCGTGAGATCAAGGAGAAGCGGCTCCGG AGCCTGTCCAGGAAGTTCACCGACTGGGCGTACGGACCCGTGTCATCCTCCCTCTACGACCTCACCAACGTGGACACCACCACGGACAAC TCAGTGCTGGAAATCACTGTCTACAACACCAACATCGACAACCGGCATGAGATGCTGACCCTGGAGCCGCTGCACACGCTGCTGCATATG AAGTGGAAGAAGTTTGCCAAGCACATGTTCTTTCTGTCCTTCTGCTTTTATTTCTTCTACAACATCACCCTGACCCTCGTCTCGTACTAC CGCCCCCGGGAGGAGGAGGCCATCCCGCACCCCTTGGCCCTGACGCACAAGATGGGGTGGCTGCAGCTCCTAGGGAGGATGTTTGTGCTC ATCTGGGCCATGTGCATCTCTGTGAAAGAGGGCATTGCCATCTTCCTGCTGAGACCCTCGGATCTGCAGTCCATCCTCTCGGATGCCTGG TTCCACTTTGTCTTTTTTATCCAAGCTGTGCTTGTGATACTGTCTGTCTTCTTGTACTTGTTTGCCTACAAAGAGTACCTCGCCTGCCTC GTGCTGGCCATGGCCCTGGGCTGGGCGAACATGCTCTACTATACGCGGGGTTTCCAGTCCATGGGCATGTACAGCGTCATGATCCAGAAG GTCATTTTGCATGATGTTCTGAAGTTCTTGTTTGTATATATCGTGTTTTTGCTTGGATTTGGAGTAGCCTTGGCCTCGCTGATCGAGAAG TGTCCCAAAGACAACAAGGACTGCAGCTCCTACGGCAGCTTCAGCGACGCAGTGCTGGAACTCTTCAAGCTCACCATAGGCCTGGGTGAC CTGAACATCCAGCAGAACTCCAAGTATCCCATTCTCTTTCTGTTCCTGCTCATCACCTATGTCATCCTCACCTTTGTTCTCCTCCTCAAC ATGCTCATTGCTCTGATGGGCGAGACTGTGGAGAACGTCTCCAAGGAGAGCGAACGCATCTGGCGCCTGCAGAGAGCCAGGACCATCTTG GAGTTTGAGAAAATGTTACCAGAATGGCTGAGGAGCAGATTCCGGATGGGAGAGCTGTGCAAAGTGGCCGAGGATGATTTCCGACTGTGT TTGCGGATCAATGAGGTGAAGTGGACTGAATGGAAGACGCACGTCTCCTTCCTTAACGAAGACCCGGGGCCTGTAAGACGAACAGCAGAT TTCAACAAAATCCAAGATTCTTCCAGGAACAACAGCAAAACCACTCTCAATGCATTTGAAGAAGTCGAGGAATTCCCGGAAACCTCGGTG >In-frame_PKM_ENST00000449901_chr15_72502014_-_TRPV3_ENST00000576742_chr17_3439007_-_2250nt ATGTCACCGGAAGCCCAACCCCAGAGAACCAAAGGACCTCAGCAGCCATGTCGAAGCCCCATAGTGAAGCCGGGACTGCCTTCATTCAGA CCCAGCAGCTGCACGCAGCCATGGCTGACACATTCCTGGAGCACATGTGCCGCCTGGACATTGATTCACCACCCATCACAGCCCGGAACA CTGGCATCATCTGTACCATTGTACCATGCGGAGACCATCAAGAATGTGCGCACAGCCACGGAAAGCTTTGCTTCTGACCCCATCCTCTAC CGGCCCGTTGCTGTGGCTCTAGACACTAAAGGACCTGAGATCCGAACTGGGCTCATCAAGGGCAGCGGCACTGCAGAGGTGGAGCTGAAG AAGGGAGCCACTCTCAAAATCACGCTGGATAACGCCTACATGGAAAAGTGTGACGAGAACATCCTGTGGCTGGACTACAAGAACATCTGC AAGGTGGTGGAAGTGGGCAGCAAGATCTACGTGGATGATGGGCTTATTTCTCTCCAGGTGAAGCAGAAAGGGCAGACGGCGCTGAACATC GCCATCGAGCGGCGGCAGGGGGACATCGCAGCCCTGCTCATCGCCGCCGGCGCCGACGTCAACGCGCACGCCAAGGGGGCCTTCTTCAAC CCCAAGTACCAACACGAAGGCTTCTACTTCGGTGAGACGCCCCTGGCCCTGGCAGCATGCACCAACCAGCCCGAGATTGTGCAGCTGCTG ATGGAGCACGAGCAGACGGACATCACCTCGCGGGACTCACGAGGCAACAACATCCTTCACGCCCTGGTGACCGTGGCCGAGGACTTCAAG ACGCAGAATGACTTTGTGAAGCGCATGTACGACATGATCCTACTGCGGAGTGGCAACTGGGAGCTGGAGACCACTCGCAACAACGATGGC CTCACGCCGCTGCAGCTGGCCGCCAAGATGGGCAAGGCGGAGATCCTGAAGTACATCCTCAGTCGTGAGATCAAGGAGAAGCGGCTCCGG AGCCTGTCCAGGAAGTTCACCGACTGGGCGTACGGACCCGTGTCATCCTCCCTCTACGACCTCACCAACGTGGACACCACCACGGACAAC TCAGTGCTGGAAATCACTGTCTACAACACCAACATCGACAACCGGCATGAGATGCTGACCCTGGAGCCGCTGCACACGCTGCTGCATATG AAGTGGAAGAAGTTTGCCAAGCACATGTTCTTTCTGTCCTTCTGCTTTTATTTCTTCTACAACATCACCCTGACCCTCGTCTCGTACTAC CGCCCCCGGGAGGAGGAGGCCATCCCGCACCCCTTGGCCCTGACGCACAAGATGGGGTGGCTGCAGCTCCTAGGGAGGATGTTTGTGCTC ATCTGGGCCATGTGCATCTCTGTGAAAGAGGGCATTGCCATCTTCCTGCTGAGACCCTCGGATCTGCAGTCCATCCTCTCGGATGCCTGG TTCCACTTTGTCTTTTTTATCCAAGCTGTGCTTGTGATACTGTCTGTCTTCTTGTACTTGTTTGCCTACAAAGAGTACCTCGCCTGCCTC GTGCTGGCCATGGCCCTGGGCTGGGCGAACATGCTCTACTATACGCGGGGTTTCCAGTCCATGGGCATGTACAGCGTCATGATCCAGAAG GTCATTTTGCATGATGTTCTGAAGTTCTTGTTTGTATATATCGTGTTTTTGCTTGGATTTGGAGTAGCCTTGGCCTCGCTGATCGAGAAG TGTCCCAAAGACAACAAGGACTGCAGCTCCTACGGCAGCTTCAGCGACGCAGTGCTGGAACTCTTCAAGCTCACCATAGGCCTGGGTGAC CTGAACATCCAGCAGAACTCCAAGTATCCCATTCTCTTTCTGTTCCTGCTCATCACCTATGTCATCCTCACCTTTGTTCTCCTCCTCAAC ATGCTCATTGCTCTGATGGGCGAGACTGTGGAGAACGTCTCCAAGGAGAGCGAACGCATCTGGCGCCTGCAGAGAGCCAGGACCATCTTG GAGTTTGAGAAAATGTTACCAGAATGGCTGAGGAGCAGATTCCGGATGGGAGAGCTGTGCAAAGTGGCCGAGGATGATTTCCGACTGTGT TTGCGGATCAATGAGGTGAAGTGGACTGAATGGAAGACGCACGTCTCCTTCCTTAACGAAGACCCGGGGCCTGTAAGACGAACAGATTTC AACAAAATCCAAGATTCTTCCAGGAACAACAGCAAAACCACTCTCAATGCATTTGAAGAAGTCGAGGAATTCCCGGAAACCTCGGTGTAG >In-frame_PKM_ENST00000449901_chr15_72502014_-_TRPV3_ENST00000572519_chr17_3439007_-_2175nt ATGTCACCGGAAGCCCAACCCCAGAGAACCAAAGGACCTCAGCAGCCATGTCGAAGCCCCATAGTGAAGCCGGGACTGCCTTCATTCAGA CCCAGCAGCTGCACGCAGCCATGGCTGACACATTCCTGGAGCACATGTGCCGCCTGGACATTGATTCACCACCCATCACAGCCCGGAACA CTGGCATCATCTGTACCATTGTACCATGCGGAGACCATCAAGAATGTGCGCACAGCCACGGAAAGCTTTGCTTCTGACCCCATCCTCTAC CGGCCCGTTGCTGTGGCTCTAGACACTAAAGGACCTGAGATCCGAACTGGGCTCATCAAGGGCAGCGGCACTGCAGAGGTGGAGCTGAAG AAGGGAGCCACTCTCAAAATCACGCTGGATAACGCCTACATGGAAAAGTGTGACGAGAACATCCTGTGGCTGGACTACAAGAACATCTGC AAGGTGGTGGAAGTGGGCAGCAAGATCTACGTGGATGATGGGCTTATTTCTCTCCAGGTGAAGCAGAAAGGGCAGACGGCGCTGAACATC GCCATCGAGCGGCGGCAGGGGGACATCGCAGCCCTGCTCATCGCCGCCGGCGCCGACGTCAACGCGCACGCCAAGGGGGCCTTCTTCAAC CCCAAGTACCAACACGAAGGCTTCTACTTCGGTGAGACGCCCCTGGCCCTGGCAGCATGCACCAACCAGCCCGAGATTGTGCAGCTGCTG ATGGAGCACGAGCAGACGGACATCACCTCGCGGGACTCACGAGGCAACAACATCCTTCACGCCCTGGTGACCGTGGCCGAGGACTTCAAG ACGCAGAATGACTTTGTGAAGCGCATGTACGACATGATCCTACTGCGGAGTGGCAACTGGGAGCTGGAGACCACTCGCAACAACGATGGC CTCACGCCGCTGCAGCTGGCCGCCAAGATGGGCAAGGCGGAGATCCTGAAGTACATCCTCAGTCGTGAGATCAAGGAGAAGCGGCTCCGG AGCCTGTCCAGGAAGTTCACCGACTGGGCGTACGGACCCGTGTCATCCTCCCTCTACGACCTCACCAACGTGGACACCACCACGGACAAC TCAGTGCTGGAAATCACTGTCTACAACACCAACATCGACAACCGGCATGAGATGCTGACCCTGGAGCCGCTGCACACGCTGCTGCATATG AAGTGGAAGAAGTTTGCCAAGCACATGTTCTTTCTGTCCTTCTGCTTTTATTTCTTCTACAACATCACCCTGACCCTCGTCTCGTACTAC CGCCCCCGGGAGGAGGAGGCCATCCCGCACCCCTTGGCCCTGACGCACAAGATGGGGTGGCTGCAGCTCCTAGGGAGGATGTTTGTGCTC ATCTGGGCCATGTGCATCTCTGTGAAAGAGGGCATTGCCATCTTCCTGCTGAGACCCTCGGATCTGCAGTCCATCCTCTCGGATGCCTGG TTCCACTTTGTCTTTTTTATCCAAGCTGTGCTTGTGATACTGTCTGTCTTCTTGTACTTGTTTGCCTACAAAGAGTACCTCGCCTGCCTC GTGCTGGCCATGGCCCTGGGCTGGGCGAACATGCTCTACTATACGCGGGGTTTCCAGTCCATGGGCATGTACAGCGTCATGATCCAGAAG GTCATTTTGCATGATGTTCTGAAGTTCTTGTTTGTATATATCGTGTTTTTGCTTGGATTTGGAGTAGCCTTGGCCTCGCTGATCGAGAAG TGTCCCAAAGACAACAAGGACTGCAGCTCCTACGGCAGCTTCAGCGACGCAGTGCTGGAACTCTTCAAGCTCACCATAGGCCTGGGTGAC CTGAACATCCAGCAGAACTCCAAGTATCCCATTCTCTTTCTGTTCCTGCTCATCACCTATGTCATCCTCACCTTTGTTCTCCTCCTCAAC ATGCTCATTGCTCTGATGGGCGAGACTGTGGAGAACGTCTCCAAGGAGAGCGAACGCATCTGGCGCCTGCAGAGAGCCAGGACCATCTTG GAGTTTGAGAAAATGTTACCAGAATGGCTGAGGAGCAGATTCCGGATGGGAGAGCTGTGCAAAGTGGCCGAGGATGATTTCCGACTGTGT TTGCGGATCAATGAGGTGAAGTGGACTGAATGGAAGACGCACGTCTCCTTCCTTAACGAAGACCCGGGGCCTGTAAGACGAACAGGTACT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_PKM_ENST00000449901_chr15_72502014_-_TRPV3_ENST00000301365_chr17_3439007_-_3138nt GCACAGCAGCTGCACGCGCCGTGGCTCCGGATCTCTTCGTCTTTGCAGCGTAGCCCGAGTCGGTCAGCGCCGGAGCTCTCCAGGGCACAC CGTATTCAGCTCTGAGCGGTCTTTGCTAGTGAGGCCAAGGAGCCACCCTGAGCCAAAAGGGGAGCATTATGTCACCGGAAGCCCAACCCC AGAGAACCAAAGGACCTCAGCAGCCATGTCGAAGCCCCATAGTGAAGCCGGGACTGCCTTCATTCAGACCCAGCAGCTGCACGCAGCCAT GGCTGACACATTCCTGGAGCACATGTGCCGCCTGGACATTGATTCACCACCCATCACAGCCCGGAACACTGGCATCATCTGTACCATTGT ACCATGCGGAGACCATCAAGAATGTGCGCACAGCCACGGAAAGCTTTGCTTCTGACCCCATCCTCTACCGGCCCGTTGCTGTGGCTCTAG ACACTAAAGGACCTGAGATCCGAACTGGGCTCATCAAGGGCAGCGGCACTGCAGAGGTGGAGCTGAAGAAGGGAGCCACTCTCAAAATCA CGCTGGATAACGCCTACATGGAAAAGTGTGACGAGAACATCCTGTGGCTGGACTACAAGAACATCTGCAAGGTGGTGGAAGTGGGCAGCA AGATCTACGTGGATGATGGGCTTATTTCTCTCCAGGTGAAGCAGAAAGGGCAGACGGCGCTGAACATCGCCATCGAGCGGCGGCAGGGGG ACATCGCAGCCCTGCTCATCGCCGCCGGCGCCGACGTCAACGCGCACGCCAAGGGGGCCTTCTTCAACCCCAAGTACCAACACGAAGGCT TCTACTTCGGTGAGACGCCCCTGGCCCTGGCAGCATGCACCAACCAGCCCGAGATTGTGCAGCTGCTGATGGAGCACGAGCAGACGGACA TCACCTCGCGGGACTCACGAGGCAACAACATCCTTCACGCCCTGGTGACCGTGGCCGAGGACTTCAAGACGCAGAATGACTTTGTGAAGC GCATGTACGACATGATCCTACTGCGGAGTGGCAACTGGGAGCTGGAGACCACTCGCAACAACGATGGCCTCACGCCGCTGCAGCTGGCCG CCAAGATGGGCAAGGCGGAGATCCTGAAGTACATCCTCAGTCGTGAGATCAAGGAGAAGCGGCTCCGGAGCCTGTCCAGGAAGTTCACCG ACTGGGCGTACGGACCCGTGTCATCCTCCCTCTACGACCTCACCAACGTGGACACCACCACGGACAACTCAGTGCTGGAAATCACTGTCT ACAACACCAACATCGACAACCGGCATGAGATGCTGACCCTGGAGCCGCTGCACACGCTGCTGCATATGAAGTGGAAGAAGTTTGCCAAGC ACATGTTCTTTCTGTCCTTCTGCTTTTATTTCTTCTACAACATCACCCTGACCCTCGTCTCGTACTACCGCCCCCGGGAGGAGGAGGCCA TCCCGCACCCCTTGGCCCTGACGCACAAGATGGGGTGGCTGCAGCTCCTAGGGAGGATGTTTGTGCTCATCTGGGCCATGTGCATCTCTG TGAAAGAGGGCATTGCCATCTTCCTGCTGAGACCCTCGGATCTGCAGTCCATCCTCTCGGATGCCTGGTTCCACTTTGTCTTTTTTATCC AAGCTGTGCTTGTGATACTGTCTGTCTTCTTGTACTTGTTTGCCTACAAAGAGTACCTCGCCTGCCTCGTGCTGGCCATGGCCCTGGGCT GGGCGAACATGCTCTACTATACGCGGGGTTTCCAGTCCATGGGCATGTACAGCGTCATGATCCAGAAGGTCATTTTGCATGATGTTCTGA AGTTCTTGTTTGTATATATCGTGTTTTTGCTTGGATTTGGAGTAGCCTTGGCCTCGCTGATCGAGAAGTGTCCCAAAGACAACAAGGACT GCAGCTCCTACGGCAGCTTCAGCGACGCAGTGCTGGAACTCTTCAAGCTCACCATAGGCCTGGGTGACCTGAACATCCAGCAGAACTCCA AGTATCCCATTCTCTTTCTGTTCCTGCTCATCACCTATGTCATCCTCACCTTTGTTCTCCTCCTCAACATGCTCATTGCTCTGATGGGCG AGACTGTGGAGAACGTCTCCAAGGAGAGCGAACGCATCTGGCGCCTGCAGAGAGCCAGGACCATCTTGGAGTTTGAGAAAATGTTACCAG AATGGCTGAGGAGCAGATTCCGGATGGGAGAGCTGTGCAAAGTGGCCGAGGATGATTTCCGACTGTGTTTGCGGATCAATGAGGTGAAGT GGACTGAATGGAAGACGCACGTCTCCTTCCTTAACGAAGACCCGGGGCCTGTAAGACGAACAGCAGATTTCAACAAAATCCAAGATTCTT CCAGGAACAACAGCAAAACCACTCTCAATGCATTTGAAGAAGTCGAGGAATTCCCGGAAACCTCGGTGTAGAAGCGGAACCCAGAGCTGG TGTGCGCGTGCGCTGTCTGGCGCTGCAGGCGGAGTCACCGACTCTGTGCAGAGAGGCTTTGAGGGATGGTGGAGTCCGGCTCTGCTGGCC TAGAAGCAGAGTGCACCCTCGTGCTCAGTGCTCAGTGGGTGTCTGAACTGAGGGGCAGTTGTCAATTTGTCTGAGTGGGAAACATCCTGG ATTTTGTTACTTGGCAAACAGCTGGTGTAAACCTACAGCCAGCAGCAGTCTGGAGCCTGGGAGCCTCCTGAAGTCCCGGGTGAAGCCTCT GGTTTTACCAATTGCAGGTCGGCTTGGCTGGGAGAGATGGATGGCGGGAAAGGGGCAGCAGTCTTGAGGAGCAGGGAGAGGAGTCTTTCC TCCTGCCAGCTTCCCCCGTCAGCCCCAACCCCAGCCCACACATTGTACCATCTCTTCTGCTGTGACTGGGTTGCCTGAATTTGTGGGAGA CCCGTGATCCCATCCCAGAGTGTGCGGGGGACGGAGGTAAGCTGGATATCCTGGGGGAGGAGGGGAATGCGCTCTGGAAACACCCTTCCG GAACCCTTCGGGGAAAAGGAGACCATCCTTGGAGTGAACGTCCCCTGACACCCCAAGGTTCAAACTGTCTCAAGCTGAGAGATGTTTTTA >In-frame_PKM_ENST00000449901_chr15_72502014_-_TRPV3_ENST00000576742_chr17_3439007_-_2479nt GCACAGCAGCTGCACGCGCCGTGGCTCCGGATCTCTTCGTCTTTGCAGCGTAGCCCGAGTCGGTCAGCGCCGGAGCTCTCCAGGGCACAC CGTATTCAGCTCTGAGCGGTCTTTGCTAGTGAGGCCAAGGAGCCACCCTGAGCCAAAAGGGGAGCATTATGTCACCGGAAGCCCAACCCC AGAGAACCAAAGGACCTCAGCAGCCATGTCGAAGCCCCATAGTGAAGCCGGGACTGCCTTCATTCAGACCCAGCAGCTGCACGCAGCCAT GGCTGACACATTCCTGGAGCACATGTGCCGCCTGGACATTGATTCACCACCCATCACAGCCCGGAACACTGGCATCATCTGTACCATTGT ACCATGCGGAGACCATCAAGAATGTGCGCACAGCCACGGAAAGCTTTGCTTCTGACCCCATCCTCTACCGGCCCGTTGCTGTGGCTCTAG ACACTAAAGGACCTGAGATCCGAACTGGGCTCATCAAGGGCAGCGGCACTGCAGAGGTGGAGCTGAAGAAGGGAGCCACTCTCAAAATCA CGCTGGATAACGCCTACATGGAAAAGTGTGACGAGAACATCCTGTGGCTGGACTACAAGAACATCTGCAAGGTGGTGGAAGTGGGCAGCA AGATCTACGTGGATGATGGGCTTATTTCTCTCCAGGTGAAGCAGAAAGGGCAGACGGCGCTGAACATCGCCATCGAGCGGCGGCAGGGGG ACATCGCAGCCCTGCTCATCGCCGCCGGCGCCGACGTCAACGCGCACGCCAAGGGGGCCTTCTTCAACCCCAAGTACCAACACGAAGGCT TCTACTTCGGTGAGACGCCCCTGGCCCTGGCAGCATGCACCAACCAGCCCGAGATTGTGCAGCTGCTGATGGAGCACGAGCAGACGGACA TCACCTCGCGGGACTCACGAGGCAACAACATCCTTCACGCCCTGGTGACCGTGGCCGAGGACTTCAAGACGCAGAATGACTTTGTGAAGC GCATGTACGACATGATCCTACTGCGGAGTGGCAACTGGGAGCTGGAGACCACTCGCAACAACGATGGCCTCACGCCGCTGCAGCTGGCCG CCAAGATGGGCAAGGCGGAGATCCTGAAGTACATCCTCAGTCGTGAGATCAAGGAGAAGCGGCTCCGGAGCCTGTCCAGGAAGTTCACCG ACTGGGCGTACGGACCCGTGTCATCCTCCCTCTACGACCTCACCAACGTGGACACCACCACGGACAACTCAGTGCTGGAAATCACTGTCT ACAACACCAACATCGACAACCGGCATGAGATGCTGACCCTGGAGCCGCTGCACACGCTGCTGCATATGAAGTGGAAGAAGTTTGCCAAGC ACATGTTCTTTCTGTCCTTCTGCTTTTATTTCTTCTACAACATCACCCTGACCCTCGTCTCGTACTACCGCCCCCGGGAGGAGGAGGCCA TCCCGCACCCCTTGGCCCTGACGCACAAGATGGGGTGGCTGCAGCTCCTAGGGAGGATGTTTGTGCTCATCTGGGCCATGTGCATCTCTG TGAAAGAGGGCATTGCCATCTTCCTGCTGAGACCCTCGGATCTGCAGTCCATCCTCTCGGATGCCTGGTTCCACTTTGTCTTTTTTATCC AAGCTGTGCTTGTGATACTGTCTGTCTTCTTGTACTTGTTTGCCTACAAAGAGTACCTCGCCTGCCTCGTGCTGGCCATGGCCCTGGGCT GGGCGAACATGCTCTACTATACGCGGGGTTTCCAGTCCATGGGCATGTACAGCGTCATGATCCAGAAGGTCATTTTGCATGATGTTCTGA AGTTCTTGTTTGTATATATCGTGTTTTTGCTTGGATTTGGAGTAGCCTTGGCCTCGCTGATCGAGAAGTGTCCCAAAGACAACAAGGACT GCAGCTCCTACGGCAGCTTCAGCGACGCAGTGCTGGAACTCTTCAAGCTCACCATAGGCCTGGGTGACCTGAACATCCAGCAGAACTCCA AGTATCCCATTCTCTTTCTGTTCCTGCTCATCACCTATGTCATCCTCACCTTTGTTCTCCTCCTCAACATGCTCATTGCTCTGATGGGCG AGACTGTGGAGAACGTCTCCAAGGAGAGCGAACGCATCTGGCGCCTGCAGAGAGCCAGGACCATCTTGGAGTTTGAGAAAATGTTACCAG AATGGCTGAGGAGCAGATTCCGGATGGGAGAGCTGTGCAAAGTGGCCGAGGATGATTTCCGACTGTGTTTGCGGATCAATGAGGTGAAGT GGACTGAATGGAAGACGCACGTCTCCTTCCTTAACGAAGACCCGGGGCCTGTAAGACGAACAGATTTCAACAAAATCCAAGATTCTTCCA GGAACAACAGCAAAACCACTCTCAATGCATTTGAAGAAGTCGAGGAATTCCCGGAAACCTCGGTGTAGAAGCGGAACCCAGAGCTGGTGT >In-frame_PKM_ENST00000449901_chr15_72502014_-_TRPV3_ENST00000572519_chr17_3439007_-_2840nt GCACAGCAGCTGCACGCGCCGTGGCTCCGGATCTCTTCGTCTTTGCAGCGTAGCCCGAGTCGGTCAGCGCCGGAGCTCTCCAGGGCACAC CGTATTCAGCTCTGAGCGGTCTTTGCTAGTGAGGCCAAGGAGCCACCCTGAGCCAAAAGGGGAGCATTATGTCACCGGAAGCCCAACCCC AGAGAACCAAAGGACCTCAGCAGCCATGTCGAAGCCCCATAGTGAAGCCGGGACTGCCTTCATTCAGACCCAGCAGCTGCACGCAGCCAT GGCTGACACATTCCTGGAGCACATGTGCCGCCTGGACATTGATTCACCACCCATCACAGCCCGGAACACTGGCATCATCTGTACCATTGT ACCATGCGGAGACCATCAAGAATGTGCGCACAGCCACGGAAAGCTTTGCTTCTGACCCCATCCTCTACCGGCCCGTTGCTGTGGCTCTAG ACACTAAAGGACCTGAGATCCGAACTGGGCTCATCAAGGGCAGCGGCACTGCAGAGGTGGAGCTGAAGAAGGGAGCCACTCTCAAAATCA CGCTGGATAACGCCTACATGGAAAAGTGTGACGAGAACATCCTGTGGCTGGACTACAAGAACATCTGCAAGGTGGTGGAAGTGGGCAGCA AGATCTACGTGGATGATGGGCTTATTTCTCTCCAGGTGAAGCAGAAAGGGCAGACGGCGCTGAACATCGCCATCGAGCGGCGGCAGGGGG ACATCGCAGCCCTGCTCATCGCCGCCGGCGCCGACGTCAACGCGCACGCCAAGGGGGCCTTCTTCAACCCCAAGTACCAACACGAAGGCT TCTACTTCGGTGAGACGCCCCTGGCCCTGGCAGCATGCACCAACCAGCCCGAGATTGTGCAGCTGCTGATGGAGCACGAGCAGACGGACA TCACCTCGCGGGACTCACGAGGCAACAACATCCTTCACGCCCTGGTGACCGTGGCCGAGGACTTCAAGACGCAGAATGACTTTGTGAAGC GCATGTACGACATGATCCTACTGCGGAGTGGCAACTGGGAGCTGGAGACCACTCGCAACAACGATGGCCTCACGCCGCTGCAGCTGGCCG CCAAGATGGGCAAGGCGGAGATCCTGAAGTACATCCTCAGTCGTGAGATCAAGGAGAAGCGGCTCCGGAGCCTGTCCAGGAAGTTCACCG ACTGGGCGTACGGACCCGTGTCATCCTCCCTCTACGACCTCACCAACGTGGACACCACCACGGACAACTCAGTGCTGGAAATCACTGTCT ACAACACCAACATCGACAACCGGCATGAGATGCTGACCCTGGAGCCGCTGCACACGCTGCTGCATATGAAGTGGAAGAAGTTTGCCAAGC ACATGTTCTTTCTGTCCTTCTGCTTTTATTTCTTCTACAACATCACCCTGACCCTCGTCTCGTACTACCGCCCCCGGGAGGAGGAGGCCA TCCCGCACCCCTTGGCCCTGACGCACAAGATGGGGTGGCTGCAGCTCCTAGGGAGGATGTTTGTGCTCATCTGGGCCATGTGCATCTCTG TGAAAGAGGGCATTGCCATCTTCCTGCTGAGACCCTCGGATCTGCAGTCCATCCTCTCGGATGCCTGGTTCCACTTTGTCTTTTTTATCC AAGCTGTGCTTGTGATACTGTCTGTCTTCTTGTACTTGTTTGCCTACAAAGAGTACCTCGCCTGCCTCGTGCTGGCCATGGCCCTGGGCT GGGCGAACATGCTCTACTATACGCGGGGTTTCCAGTCCATGGGCATGTACAGCGTCATGATCCAGAAGGTCATTTTGCATGATGTTCTGA AGTTCTTGTTTGTATATATCGTGTTTTTGCTTGGATTTGGAGTAGCCTTGGCCTCGCTGATCGAGAAGTGTCCCAAAGACAACAAGGACT GCAGCTCCTACGGCAGCTTCAGCGACGCAGTGCTGGAACTCTTCAAGCTCACCATAGGCCTGGGTGACCTGAACATCCAGCAGAACTCCA AGTATCCCATTCTCTTTCTGTTCCTGCTCATCACCTATGTCATCCTCACCTTTGTTCTCCTCCTCAACATGCTCATTGCTCTGATGGGCG AGACTGTGGAGAACGTCTCCAAGGAGAGCGAACGCATCTGGCGCCTGCAGAGAGCCAGGACCATCTTGGAGTTTGAGAAAATGTTACCAG AATGGCTGAGGAGCAGATTCCGGATGGGAGAGCTGTGCAAAGTGGCCGAGGATGATTTCCGACTGTGTTTGCGGATCAATGAGGTGAAGT GGACTGAATGGAAGACGCACGTCTCCTTCCTTAACGAAGACCCGGGGCCTGTAAGACGAACAGGTACTGTCGCTGTGAGGTGACATGGTG TCCGCTCCTGTCTCAGACCATGTAACCTTGGGCAGATCAAGTCTAAGGGTCCTGACTTTCCCCATCTGTCAAATGGGAGGGTTGAATGGA AATGCTTCTTAGGTCTCTTCCAGCTCTGACTTTTAGAACCCTAGTTGGCACAACTTTTAAAATGGCGTAGCCCTAAGCCATAGAAACACA TCATGCAGGCCGGGCGCGGTGGCTCGTGCCTGTAATCCCAGCACTTTGGGAGGACGAGTCGGGTGAATCACCTGAGGTCAGGAGTTTGAG ACCAGCCTGGCCAACATGGTGACACCTTGTCTCTACTAAAGATACAAAAATTAGCCGAACGTGGTGGCAGGTGCCTATAATCCCAGCTAC TCGAGAGGCTGAGTCAGGAGAATTGCTTGAACCTGGGAGGTGGAGGTTGCAGTGAGCTGAGATCACACCACTGCACTGCAGCCTGGGTGA 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FusionGenePPI for PKM_TRPV3 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| PKM | TRIM63, BANF1, MGMT, HERC1, H2AFX, RNF185, UCHL5, HDAC5, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, PSMA3, RAP1B, GRB7, RPP14, TK1, CDKN1A, CDK4, NAGK, SMN1, RCC1, PIN1, ANXA7, NDRG1, ARRB1, ARRB2, ISG15, TERF1, TINF2, CUL3, CUL5, CUL2, CDK2, CUL1, COPS5, SHBG, MYOC, PML, APP, ENO3, GAPDH, FUBP1, PCBP1, TKT, PRDX2, PRDX6, IKBKAP, HIF1A, EGLN1, EGLN3, EP300, VCP, TRAF3IP1, HSP90AA1, HSP90AB1, FN1, ATF2, IQCB1, ITGA4, MPG, PAN2, CD81, IGSF8, NPM1, MAPK7, HDAC6, LMO7, RELA, PAX8, RAF1, EXOSC5, MDM2, NLK, YWHAQ, FBXO6, ACAT2, ANP32A, CBS, EIF4A3, NPLOC4, PDLIM5, CAPZA2, CTPS1, IPO11, PPP1CA, PLIN3, RAD23B, SRP14, TWF2, UBA2, STAU1, HUWE1, FUS, POLE2, NXT2, LNX1, CUL7, OBSL1, CCDC8, EZH2, SUZ12, SUMO1, CDK16, HNRNPA1, AGL, AKR1A1, ALDH5A1, ALDOA, AMDHD2, ASS1, BAX, DAZAP1, DNAJA3, EEF1D, FAM49B, FH, GNG12, HNRNPD, HNRNPK, HSPB1, LYPLA2, ME1, NANS, PFKM, PGK1, C9orf64, CFL1, EEF1A1, EEF1A2, LDHA, LDHAL6A, LDHB, PAICS, PFKL, PFKP, PPID, RAB10, RAC1, RPN1, SLC3A2, TRAP1, TUBA4A, TUBB, UFM1, NTRK1, PTEN, EWSR1, PPME1, CCDC88A, ARAF, TRIM35, FGFR1, ETS1, USP7, CRY1, DDB2, EPM2A, MCM2, MCM5, CDC37, U2AF2, CDC25A, CTNNB1, CDC73, WWP2, ZNF746, CDH1, CYP1A1, SNRNP27, DDX19B, PAPLN, MYL2, AURKB, MAPK1, KPNA1, TRIM25, BRCA1 | TRPV3 | AKAP5 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for PKM_TRPV3 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Hgene | PKM | P14618 | DB11638 | Artenimol | Pyruvate kinase PKM | small molecule | approved|investigational |
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RelatedDiseases for PKM_TRPV3 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | PKM | C0027626 | Neoplasm Invasiveness | 2 | CTD_human |
| Hgene | PKM | C0024667 | Animal Mammary Neoplasms | 1 | CTD_human |
| Hgene | PKM | C0024668 | Mammary Neoplasms, Experimental | 1 | CTD_human |
| Hgene | PKM | C0029456 | Osteoporosis | 1 | CTD_human |
| Hgene | PKM | C2239176 | Liver carcinoma | 1 | CTD_human |
| Tgene | TRPV3 | C2609071 | Olmsted syndrome | 2 | ORPHANET;UNIPROT |
| Tgene | TRPV3 | C4225339 | PALMOPLANTAR KERATODERMA, NONEPIDERMOLYTIC, FOCAL 2 | 1 | ORPHANET;UNIPROT |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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