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Fusion gene ID: 27300 |
FusionGeneSummary for PITPNA_PRPF8 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PITPNA_PRPF8 | Fusion gene ID: 27300 | Hgene | Tgene | Gene symbol | PITPNA | PRPF8 | Gene ID | 5306 | 10594 |
| Gene name | phosphatidylinositol transfer protein alpha | pre-mRNA processing factor 8 | |
| Synonyms | HEL-S-36|PI-TPalpha|PITPN|VIB1A | HPRP8|PRP8|PRPC8|RP13|SNRNP220 | |
| Cytomap | 17p13.3 | 17p13.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | phosphatidylinositol transfer protein alpha isoformPI-TP-alphaepididymis secretory protein Li 36ptdIns transfer protein alphaptdInsTP alpha | pre-mRNA-processing-splicing factor 8220 kDa U5 snRNP-specific proteinPRP8 homologPRP8 pre-mRNA processing factor 8 homologU5 snRNP-specific protein (220 kD), ortholog of S. cerevisiae Prp8papoptosis-regulated protein 1apoptosis-regulated protein 2 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q00169 | Q6P2Q9 | |
| Ensembl transtripts involved in fusion gene | ENST00000313486, ENST00000539476, | ENST00000304992, ENST00000572621, ENST00000575116, | |
| Fusion gene scores | * DoF score | 9 X 8 X 7=504 | 6 X 9 X 4=216 |
| # samples | 10 | 10 | |
| ** MAII score | log2(10/504*10)=-2.33342373372519 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(10/216*10)=-1.11103131238874 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: PITPNA [Title/Abstract] AND PRPF8 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | PITPNA | GO:0015914 | phospholipid transport | 16274224|22822086 |
| Tgene | PRPF8 | GO:0000244 | spliceosomal tri-snRNP complex assembly | 20595234 |
| Tgene | PRPF8 | GO:0000398 | mRNA splicing, via spliceosome | 28781166 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LUSC | TCGA-43-8116-01A | PITPNA | chr17 | 1456298 | - | PRPF8 | chr17 | 1557310 | - |
| TCGA | RV | OV | TCGA-36-1581-01A | PITPNA | chr17 | 1444860 | - | PRPF8 | chr17 | 1565447 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000313486 | ENST00000304992 | PITPNA | chr17 | 1456298 | - | PRPF8 | chr17 | 1557310 | - |
| Frame-shift | ENST00000313486 | ENST00000572621 | PITPNA | chr17 | 1456298 | - | PRPF8 | chr17 | 1557310 | - |
| 5CDS-intron | ENST00000313486 | ENST00000575116 | PITPNA | chr17 | 1456298 | - | PRPF8 | chr17 | 1557310 | - |
| Frame-shift | ENST00000539476 | ENST00000304992 | PITPNA | chr17 | 1456298 | - | PRPF8 | chr17 | 1557310 | - |
| Frame-shift | ENST00000539476 | ENST00000572621 | PITPNA | chr17 | 1456298 | - | PRPF8 | chr17 | 1557310 | - |
| 5CDS-intron | ENST00000539476 | ENST00000575116 | PITPNA | chr17 | 1456298 | - | PRPF8 | chr17 | 1557310 | - |
| In-frame | ENST00000313486 | ENST00000304992 | PITPNA | chr17 | 1444860 | - | PRPF8 | chr17 | 1565447 | - |
| In-frame | ENST00000313486 | ENST00000572621 | PITPNA | chr17 | 1444860 | - | PRPF8 | chr17 | 1565447 | - |
| 5CDS-intron | ENST00000313486 | ENST00000575116 | PITPNA | chr17 | 1444860 | - | PRPF8 | chr17 | 1565447 | - |
| In-frame | ENST00000539476 | ENST00000304992 | PITPNA | chr17 | 1444860 | - | PRPF8 | chr17 | 1565447 | - |
| In-frame | ENST00000539476 | ENST00000572621 | PITPNA | chr17 | 1444860 | - | PRPF8 | chr17 | 1565447 | - |
| 5CDS-intron | ENST00000539476 | ENST00000575116 | PITPNA | chr17 | 1444860 | - | PRPF8 | chr17 | 1565447 | - |
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FusionProtFeatures for PITPNA_PRPF8 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| PITPNA | PRPF8 |
| Catalyzes the transfer of PtdIns and phosphatidylcholinebetween membranes. | Functions as a scaffold that mediates the orderedassembly of spliceosomal proteins and snRNAs. Required for theassembly of the U4/U6-U5 tri-snRNP complex. Functions as scaffoldthat positions spliceosomal U2, U5 and U6 snRNAs at splice siteson pre-mRNA substrates, so that splicing can occur. Interacts withboth the 5' and the 3' splice site. {ECO:0000269|PubMed:20595234,ECO:0000303|PubMed:15840809}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >PRPF8 | chr17:1444860 | chr17:1565447 | ENST00000304992 | - | 23 | 43 | 2103_2234 | 1258 | 2336 | Domain | MPN |
| Tgene | >PRPF8 | chr17:1444860 | chr17:1565447 | ENST00000572621 | - | 22 | 42 | 2103_2234 | 1258 | 2336 | Domain | MPN |
| Tgene | >PRPF8 | chr17:1444860 | chr17:1565447 | ENST00000304992 | - | 23 | 43 | 1304_1577 | 1258 | 2336 | Region | Note=Linker |
| Tgene | >PRPF8 | chr17:1444860 | chr17:1565447 | ENST00000304992 | - | 23 | 43 | 1513_1526 | 1258 | 2336 | Region | Important for branch point selection |
| Tgene | >PRPF8 | chr17:1444860 | chr17:1565447 | ENST00000304992 | - | 23 | 43 | 1581_1752 | 1258 | 2336 | Region | Note=Restriction endonuclease homology domain |
| Tgene | >PRPF8 | chr17:1444860 | chr17:1565447 | ENST00000304992 | - | 23 | 43 | 1767_2020 | 1258 | 2336 | Region | Note=RNase H homology domain |
| Tgene | >PRPF8 | chr17:1444860 | chr17:1565447 | ENST00000572621 | - | 22 | 42 | 1304_1577 | 1258 | 2336 | Region | Note=Linker |
| Tgene | >PRPF8 | chr17:1444860 | chr17:1565447 | ENST00000572621 | - | 22 | 42 | 1513_1526 | 1258 | 2336 | Region | Important for branch point selection |
| Tgene | >PRPF8 | chr17:1444860 | chr17:1565447 | ENST00000572621 | - | 22 | 42 | 1581_1752 | 1258 | 2336 | Region | Note=Restriction endonuclease homology domain |
| Tgene | >PRPF8 | chr17:1444860 | chr17:1565447 | ENST00000572621 | - | 22 | 42 | 1767_2020 | 1258 | 2336 | Region | Note=RNase H homology domain |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | PRPF8 | chr17:1444860 | chr17:1565447 | ENST00000304992 | - | 23 | 43 | 812_1303 | 1258 | 2336 | Region | Note=Reverse transcriptase homology domain |
| Tgene | PRPF8 | chr17:1444860 | chr17:1565447 | ENST00000572621 | - | 22 | 42 | 812_1303 | 1258 | 2336 | Region | Note=Reverse transcriptase homology domain |
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FusionGeneSequence for PITPNA_PRPF8 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_PITPNA_ENST00000313486_chr17_1444860_-_PRPF8_ENST00000304992_chr17_1565447_-_1202aa MVLLKEYRVILPVSVDEYQVGQLYSVAEASKNETGGGEGVEVLVNEPYEKDGEKGQYTHKIYHLQSKVPTFVRMLAPEGALNIHEKAWNA YPYCRTVITNEYMKEDFLIKIETWHKPDLGTQENIVNKWNTALIGLMTYFREAVVNTQELLDLLVKCENKIQTRIKIGLNSKMPSRFPPV VFYTPKELGGLGMLSMGHVLIPQSDLRWSKQTDVGITHFRSGMSHEEDQLIPNLYRYIQPWESEFIDSQRVWAEYALKRQEAIAQNRRLT LEDLEDSWDRGIPRINTLFQKDRHTLAYDKGWRVRTDFKQYQVLKQNPFWWTHQRHDGKLWNLNNYRTDMIQALGGVEGILEHTLFKGTY FPTWEGLFWEKASGFEESMKWKKLTNAQRSGLNQIPNRRFTLWWSPTINRANVYVGFQVQLDLTGIFMHGKIPTLKISLIQIFRAHLWQK IHESIVMDLCQVFDQELDALEIETVQKETIHPRKSYKMNSSCADILLFASYKWNVSRPSLLADSKDVMDSTTTQKYWIDIQLRWGDYDSH DIERYARAKFLDYTTDNMSIYPSPTGVLIAIDLAYNLHSAYGNWFPGSKPLIQQAMAKIMKANPALYVLRERIRKGLQLYSSEPTEPYLS SQNYGELFSNQIIWFVDDTNVYRVTIHKTFEGNLTTKPINGAIFIFNPRTGQLFLKIIHTSVWAGQKRLGQLAKWKTAEEVAALIRSLPV EEQPKQIIVTRKGMLDPLEVHLLDFPNIVIKGSELQLPFQACLKVEKFGDLILKATEPQMVLFNLYDDWLKTISSYTAFSRLILILRALH VNNDRAKVILKPDKTTITEPHHIWPTLTDEEWIKVEVQLKDLILADYGKKNNVNVASLTQSEIRDIILGMEISAPSQQRQQIAEIEKQTK EQSQLTATQTRTVNKHGDEIITSTTSNYETQTFSSKTEWRVRAISAANLHLRTNHIYVSSDDIKETGYTYILPKNVLKKFICISDLRAQI AGYLYGVSPPDNPQVKEIRCIVMVPQWGTHQTVHLPGQLPQHEYLKEMEPLGWIHTQPNESPQLSPQDVTTHAKIMADNPSWDGEKTIII TCSFTPGSCTLTAYKLTPSGYEWGRQNTDKGNNPKGYLPSHYERVQMLLSDRFLGFFMVPAQSSWNYNFMGVRHDPNMKYELQLANPKEF >In-frame_PITPNA_ENST00000313486_chr17_1444860_-_PRPF8_ENST00000572621_chr17_1565447_-_1202aa MVLLKEYRVILPVSVDEYQVGQLYSVAEASKNETGGGEGVEVLVNEPYEKDGEKGQYTHKIYHLQSKVPTFVRMLAPEGALNIHEKAWNA YPYCRTVITNEYMKEDFLIKIETWHKPDLGTQENIVNKWNTALIGLMTYFREAVVNTQELLDLLVKCENKIQTRIKIGLNSKMPSRFPPV VFYTPKELGGLGMLSMGHVLIPQSDLRWSKQTDVGITHFRSGMSHEEDQLIPNLYRYIQPWESEFIDSQRVWAEYALKRQEAIAQNRRLT LEDLEDSWDRGIPRINTLFQKDRHTLAYDKGWRVRTDFKQYQVLKQNPFWWTHQRHDGKLWNLNNYRTDMIQALGGVEGILEHTLFKGTY FPTWEGLFWEKASGFEESMKWKKLTNAQRSGLNQIPNRRFTLWWSPTINRANVYVGFQVQLDLTGIFMHGKIPTLKISLIQIFRAHLWQK IHESIVMDLCQVFDQELDALEIETVQKETIHPRKSYKMNSSCADILLFASYKWNVSRPSLLADSKDVMDSTTTQKYWIDIQLRWGDYDSH DIERYARAKFLDYTTDNMSIYPSPTGVLIAIDLAYNLHSAYGNWFPGSKPLIQQAMAKIMKANPALYVLRERIRKGLQLYSSEPTEPYLS SQNYGELFSNQIIWFVDDTNVYRVTIHKTFEGNLTTKPINGAIFIFNPRTGQLFLKIIHTSVWAGQKRLGQLAKWKTAEEVAALIRSLPV EEQPKQIIVTRKGMLDPLEVHLLDFPNIVIKGSELQLPFQACLKVEKFGDLILKATEPQMVLFNLYDDWLKTISSYTAFSRLILILRALH VNNDRAKVILKPDKTTITEPHHIWPTLTDEEWIKVEVQLKDLILADYGKKNNVNVASLTQSEIRDIILGMEISAPSQQRQQIAEIEKQTK EQSQLTATQTRTVNKHGDEIITSTTSNYETQTFSSKTEWRVRAISAANLHLRTNHIYVSSDDIKETGYTYILPKNVLKKFICISDLRAQI AGYLYGVSPPDNPQVKEIRCIVMVPQWGTHQTVHLPGQLPQHEYLKEMEPLGWIHTQPNESPQLSPQDVTTHAKIMADNPSWDGEKTIII TCSFTPGSCTLTAYKLTPSGYEWGRQNTDKGNNPKGYLPSHYERVQMLLSDRFLGFFMVPAQSSWNYNFMGVRHDPNMKYELQLANPKEF >In-frame_PITPNA_ENST00000539476_chr17_1444860_-_PRPF8_ENST00000304992_chr17_1565447_-_1202aa MVLLKEYRVILPVSVDEYQVGQLYSVAEASKNETGGGEGVEVLVNEPYEKDGEKGQYTHKIYHLQSKVPTFVRMLAPEGALNIHEKAWNA YPYCRTVLPNEYMKEDFLIKIETWHKPDLGTQENIVNKWNTALIGLMTYFREAVVNTQELLDLLVKCENKIQTRIKIGLNSKMPSRFPPV VFYTPKELGGLGMLSMGHVLIPQSDLRWSKQTDVGITHFRSGMSHEEDQLIPNLYRYIQPWESEFIDSQRVWAEYALKRQEAIAQNRRLT LEDLEDSWDRGIPRINTLFQKDRHTLAYDKGWRVRTDFKQYQVLKQNPFWWTHQRHDGKLWNLNNYRTDMIQALGGVEGILEHTLFKGTY FPTWEGLFWEKASGFEESMKWKKLTNAQRSGLNQIPNRRFTLWWSPTINRANVYVGFQVQLDLTGIFMHGKIPTLKISLIQIFRAHLWQK IHESIVMDLCQVFDQELDALEIETVQKETIHPRKSYKMNSSCADILLFASYKWNVSRPSLLADSKDVMDSTTTQKYWIDIQLRWGDYDSH DIERYARAKFLDYTTDNMSIYPSPTGVLIAIDLAYNLHSAYGNWFPGSKPLIQQAMAKIMKANPALYVLRERIRKGLQLYSSEPTEPYLS SQNYGELFSNQIIWFVDDTNVYRVTIHKTFEGNLTTKPINGAIFIFNPRTGQLFLKIIHTSVWAGQKRLGQLAKWKTAEEVAALIRSLPV EEQPKQIIVTRKGMLDPLEVHLLDFPNIVIKGSELQLPFQACLKVEKFGDLILKATEPQMVLFNLYDDWLKTISSYTAFSRLILILRALH VNNDRAKVILKPDKTTITEPHHIWPTLTDEEWIKVEVQLKDLILADYGKKNNVNVASLTQSEIRDIILGMEISAPSQQRQQIAEIEKQTK EQSQLTATQTRTVNKHGDEIITSTTSNYETQTFSSKTEWRVRAISAANLHLRTNHIYVSSDDIKETGYTYILPKNVLKKFICISDLRAQI AGYLYGVSPPDNPQVKEIRCIVMVPQWGTHQTVHLPGQLPQHEYLKEMEPLGWIHTQPNESPQLSPQDVTTHAKIMADNPSWDGEKTIII TCSFTPGSCTLTAYKLTPSGYEWGRQNTDKGNNPKGYLPSHYERVQMLLSDRFLGFFMVPAQSSWNYNFMGVRHDPNMKYELQLANPKEF >In-frame_PITPNA_ENST00000539476_chr17_1444860_-_PRPF8_ENST00000572621_chr17_1565447_-_1202aa MVLLKEYRVILPVSVDEYQVGQLYSVAEASKNETGGGEGVEVLVNEPYEKDGEKGQYTHKIYHLQSKVPTFVRMLAPEGALNIHEKAWNA YPYCRTVLPNEYMKEDFLIKIETWHKPDLGTQENIVNKWNTALIGLMTYFREAVVNTQELLDLLVKCENKIQTRIKIGLNSKMPSRFPPV VFYTPKELGGLGMLSMGHVLIPQSDLRWSKQTDVGITHFRSGMSHEEDQLIPNLYRYIQPWESEFIDSQRVWAEYALKRQEAIAQNRRLT LEDLEDSWDRGIPRINTLFQKDRHTLAYDKGWRVRTDFKQYQVLKQNPFWWTHQRHDGKLWNLNNYRTDMIQALGGVEGILEHTLFKGTY FPTWEGLFWEKASGFEESMKWKKLTNAQRSGLNQIPNRRFTLWWSPTINRANVYVGFQVQLDLTGIFMHGKIPTLKISLIQIFRAHLWQK IHESIVMDLCQVFDQELDALEIETVQKETIHPRKSYKMNSSCADILLFASYKWNVSRPSLLADSKDVMDSTTTQKYWIDIQLRWGDYDSH DIERYARAKFLDYTTDNMSIYPSPTGVLIAIDLAYNLHSAYGNWFPGSKPLIQQAMAKIMKANPALYVLRERIRKGLQLYSSEPTEPYLS SQNYGELFSNQIIWFVDDTNVYRVTIHKTFEGNLTTKPINGAIFIFNPRTGQLFLKIIHTSVWAGQKRLGQLAKWKTAEEVAALIRSLPV EEQPKQIIVTRKGMLDPLEVHLLDFPNIVIKGSELQLPFQACLKVEKFGDLILKATEPQMVLFNLYDDWLKTISSYTAFSRLILILRALH VNNDRAKVILKPDKTTITEPHHIWPTLTDEEWIKVEVQLKDLILADYGKKNNVNVASLTQSEIRDIILGMEISAPSQQRQQIAEIEKQTK EQSQLTATQTRTVNKHGDEIITSTTSNYETQTFSSKTEWRVRAISAANLHLRTNHIYVSSDDIKETGYTYILPKNVLKKFICISDLRAQI AGYLYGVSPPDNPQVKEIRCIVMVPQWGTHQTVHLPGQLPQHEYLKEMEPLGWIHTQPNESPQLSPQDVTTHAKIMADNPSWDGEKTIII TCSFTPGSCTLTAYKLTPSGYEWGRQNTDKGNNPKGYLPSHYERVQMLLSDRFLGFFMVPAQSSWNYNFMGVRHDPNMKYELQLANPKEF |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_PITPNA_ENST00000313486_chr17_1444860_-_PRPF8_ENST00000304992_chr17_1565447_-_3606nt ATGGTGCTGCTCAAGGAGTATCGAGTAATCCTGCCTGTGTCTGTAGATGAGTATCAAGTGGGGCAGCTGTATTCTGTGGCTGAGGCCAGT AAAAATGAAACGGGTGGTGGCGAAGGCGTGGAGGTCCTGGTGAATGAGCCCTACGAGAAGGACGGTGAGAAAGGCCAGTACACACACAAG ATCTACCACCTGCAGAGCAAAGTACCCACGTTTGTTCGAATGCTGGCCCCAGAGGGAGCCCTGAATATACACGAGAAAGCCTGGAATGCT TACCCCTACTGCAGAACCGTTATTACAAATGAGTACATGAAAGAAGACTTTCTGATTAAAATTGAAACCTGGCACAAACCAGATCTTGGC ACGCAGGAGAATATTGTGAATAAGTGGAATACAGCTCTCATTGGCCTTATGACATACTTTCGGGAGGCTGTGGTGAACACCCAAGAGCTC TTGGACTTACTGGTGAAGTGTGAGAACAAAATCCAGACACGTATCAAGATTGGACTCAACTCCAAGATGCCAAGTCGGTTCCCCCCGGTT GTGTTCTACACCCCTAAGGAGTTGGGTGGACTCGGCATGCTCTCAATGGGCCATGTGCTCATCCCCCAATCCGACCTCAGGTGGTCCAAA CAGACAGATGTAGGTATCACACACTTTCGTTCAGGAATGAGCCATGAAGAAGACCAGCTCATTCCCAACTTGTACCGCTACATACAGCCA TGGGAGAGCGAGTTCATTGATTCTCAGCGGGTCTGGGCTGAGTACGCACTCAAGAGGCAAGAGGCCATTGCTCAGAACAGACGCCTGACT TTAGAAGACCTAGAAGATTCATGGGATCGTGGCATTCCTCGAATCAATACCCTCTTCCAGAAGGACCGGCACACACTGGCTTATGATAAG GGCTGGCGTGTCAGAACTGACTTTAAGCAGTATCAGGTTTTGAAGCAGAATCCGTTCTGGTGGACACACCAGCGGCATGATGGGAAGCTC TGGAACCTGAACAACTACCGTACAGACATGATCCAGGCCCTGGGCGGTGTGGAAGGCATTCTGGAACACACACTCTTTAAGGGCACTTAC TTCCCTACCTGGGAGGGGCTTTTCTGGGAGAAGGCCAGTGGCTTTGAGGAATCTATGAAGTGGAAGAAGCTAACTAATGCTCAGCGATCA GGACTGAACCAGATTCCCAATCGTAGATTCACCCTCTGGTGGTCCCCGACCATTAATCGAGCCAATGTATATGTAGGCTTTCAGGTGCAG CTAGACCTGACGGGTATCTTCATGCACGGCAAGATCCCCACGCTGAAGATCTCTCTCATCCAGATCTTCCGAGCTCACTTGTGGCAGAAG ATCCATGAGAGCATTGTTATGGACTTATGTCAGGTGTTTGACCAGGAACTTGATGCACTGGAAATTGAGACAGTACAAAAGGAGACAATC CATCCCCGAAAGTCATATAAGATGAACTCTTCCTGTGCAGATATCCTGCTCTTTGCCTCCTATAAGTGGAATGTCTCCCGGCCCTCATTG CTGGCTGACTCCAAGGATGTGATGGACAGCACCACCACCCAGAAATACTGGATTGACATCCAGTTGCGCTGGGGGGACTATGATTCCCAC GACATTGAGCGCTACGCCCGGGCCAAGTTCCTGGACTACACCACCGACAACATGAGTATCTACCCTTCGCCCACAGGTGTACTCATCGCC ATTGACCTGGCCTATAACTTGCACAGTGCCTATGGAAACTGGTTCCCAGGCAGCAAGCCTCTCATACAACAGGCCATGGCCAAGATCATG AAGGCAAACCCTGCCCTGTATGTGTTACGTGAACGGATCCGCAAGGGGCTACAGCTCTATTCATCTGAACCCACTGAGCCTTATTTGTCT TCTCAGAACTATGGTGAGCTCTTCTCCAACCAGATTATCTGGTTTGTGGATGACACCAACGTCTACAGAGTGACTATTCACAAGACCTTT GAAGGGAACTTGACAACCAAGCCCATCAACGGAGCCATCTTCATCTTCAACCCACGCACAGGGCAGCTGTTCCTCAAGATAATCCACACG TCCGTGTGGGCGGGACAGAAGCGTTTGGGGCAGTTGGCTAAGTGGAAGACAGCTGAGGAGGTGGCCGCCCTGATCCGATCTCTGCCTGTG GAGGAGCAGCCCAAGCAGATCATTGTCACCAGGAAGGGCATGCTGGACCCACTGGAGGTGCACTTACTGGACTTCCCCAATATTGTCATC AAAGGATCGGAGCTCCAACTCCCTTTCCAGGCGTGTCTCAAGGTGGAAAAATTCGGGGATCTCATCCTTAAAGCCACTGAGCCCCAGATG GTTCTCTTCAACCTCTATGACGACTGGCTCAAGACTATTTCATCTTACACGGCCTTCTCCCGTCTCATCCTGATTCTGCGTGCCCTACAT GTGAACAACGATCGGGCAAAAGTGATCCTGAAGCCAGACAAGACTACTATTACAGAACCACACCACATCTGGCCCACTCTGACTGACGAA GAATGGATCAAGGTCGAGGTGCAGCTCAAGGATCTGATCTTGGCTGACTACGGCAAGAAAAACAATGTGAACGTGGCATCACTGACACAA TCAGAAATTCGAGACATCATCCTGGGTATGGAGATCTCGGCACCGTCACAGCAGCGGCAGCAGATCGCTGAGATCGAGAAGCAGACCAAG GAACAATCGCAGCTGACGGCAACACAGACTCGCACTGTCAACAAGCATGGCGATGAGATCATCACCTCCACCACCAGCAACTATGAGACC CAGACTTTCTCATCCAAGACTGAGTGGAGGGTCAGGGCCATCTCTGCTGCCAACCTGCACCTAAGGACCAATCACATCTATGTTTCATCT GACGACATCAAGGAGACTGGCTACACCTACATCCTTCCCAAGAATGTGCTTAAGAAGTTCATCTGCATATCTGACCTTCGGGCCCAAATT GCAGGATACCTATATGGGGTGAGCCCACCAGATAACCCCCAGGTGAAGGAGATCCGCTGCATTGTGATGGTGCCGCAGTGGGGCACTCAC CAGACCGTGCACCTGCCTGGCCAGCTGCCCCAGCATGAGTACCTCAAGGAGATGGAACCCTTAGGTTGGATCCACACTCAGCCCAATGAG TCCCCGCAGTTATCACCCCAGGATGTCACCACCCATGCCAAGATCATGGCTGACAACCCATCTTGGGATGGCGAGAAGACCATTATCATC ACATGCAGCTTCACGCCAGGCTCCTGTACACTGACGGCCTACAAGCTGACCCCCAGTGGCTACGAATGGGGCCGCCAGAACACAGACAAG GGCAACAACCCCAAGGGCTACCTGCCTTCACACTATGAGAGGGTGCAGATGCTGCTGTCGGACCGTTTCCTTGGCTTCTTCATGGTCCCT GCCCAGTCCTCGTGGAACTACAACTTCATGGGTGTTCGGCATGACCCCAACATGAAATATGAGCTACAGCTGGCGAACCCCAAAGAGTTC TACCACGAGGTGCACAGGCCCTCTCACTTCCTCAACTTTGCTCTCCTGCAGGAGGGGGAGGTTTACTCTGCGGATCGGGAGGACCTGTAT >In-frame_PITPNA_ENST00000313486_chr17_1444860_-_PRPF8_ENST00000572621_chr17_1565447_-_3606nt ATGGTGCTGCTCAAGGAGTATCGAGTAATCCTGCCTGTGTCTGTAGATGAGTATCAAGTGGGGCAGCTGTATTCTGTGGCTGAGGCCAGT AAAAATGAAACGGGTGGTGGCGAAGGCGTGGAGGTCCTGGTGAATGAGCCCTACGAGAAGGACGGTGAGAAAGGCCAGTACACACACAAG ATCTACCACCTGCAGAGCAAAGTACCCACGTTTGTTCGAATGCTGGCCCCAGAGGGAGCCCTGAATATACACGAGAAAGCCTGGAATGCT TACCCCTACTGCAGAACCGTTATTACAAATGAGTACATGAAAGAAGACTTTCTGATTAAAATTGAAACCTGGCACAAACCAGATCTTGGC ACGCAGGAGAATATTGTGAATAAGTGGAATACAGCTCTCATTGGCCTTATGACATACTTTCGGGAGGCTGTGGTGAACACCCAAGAGCTC TTGGACTTACTGGTGAAGTGTGAGAACAAAATCCAGACACGTATCAAGATTGGACTCAACTCCAAGATGCCAAGTCGGTTCCCCCCGGTT GTGTTCTACACCCCTAAGGAGTTGGGTGGACTCGGCATGCTCTCAATGGGCCATGTGCTCATCCCCCAATCCGACCTCAGGTGGTCCAAA CAGACAGATGTAGGTATCACACACTTTCGTTCAGGAATGAGCCATGAAGAAGACCAGCTCATTCCCAACTTGTACCGCTACATACAGCCA TGGGAGAGCGAGTTCATTGATTCTCAGCGGGTCTGGGCTGAGTACGCACTCAAGAGGCAAGAGGCCATTGCTCAGAACAGACGCCTGACT TTAGAAGACCTAGAAGATTCATGGGATCGTGGCATTCCTCGAATCAATACCCTCTTCCAGAAGGACCGGCACACACTGGCTTATGATAAG GGCTGGCGTGTCAGAACTGACTTTAAGCAGTATCAGGTTTTGAAGCAGAATCCGTTCTGGTGGACACACCAGCGGCATGATGGGAAGCTC TGGAACCTGAACAACTACCGTACAGACATGATCCAGGCCCTGGGCGGTGTGGAAGGCATTCTGGAACACACACTCTTTAAGGGCACTTAC TTCCCTACCTGGGAGGGGCTTTTCTGGGAGAAGGCCAGTGGCTTTGAGGAATCTATGAAGTGGAAGAAGCTAACTAATGCTCAGCGATCA GGACTGAACCAGATTCCCAATCGTAGATTCACCCTCTGGTGGTCCCCGACCATTAATCGAGCCAATGTATATGTAGGCTTTCAGGTGCAG CTAGACCTGACGGGTATCTTCATGCACGGCAAGATCCCCACGCTGAAGATCTCTCTCATCCAGATCTTCCGAGCTCACTTGTGGCAGAAG ATCCATGAGAGCATTGTTATGGACTTATGTCAGGTGTTTGACCAGGAACTTGATGCACTGGAAATTGAGACAGTACAAAAGGAGACAATC CATCCCCGAAAGTCATATAAGATGAACTCTTCCTGTGCAGATATCCTGCTCTTTGCCTCCTATAAGTGGAATGTCTCCCGGCCCTCATTG CTGGCTGACTCCAAGGATGTGATGGACAGCACCACCACCCAGAAATACTGGATTGACATCCAGTTGCGCTGGGGGGACTATGATTCCCAC GACATTGAGCGCTACGCCCGGGCCAAGTTCCTGGACTACACCACCGACAACATGAGTATCTACCCTTCGCCCACAGGTGTACTCATCGCC ATTGACCTGGCCTATAACTTGCACAGTGCCTATGGAAACTGGTTCCCAGGCAGCAAGCCTCTCATACAACAGGCCATGGCCAAGATCATG AAGGCAAACCCTGCCCTGTATGTGTTACGTGAACGGATCCGCAAGGGGCTACAGCTCTATTCATCTGAACCCACTGAGCCTTATTTGTCT TCTCAGAACTATGGTGAGCTCTTCTCCAACCAGATTATCTGGTTTGTGGATGACACCAACGTCTACAGAGTGACTATTCACAAGACCTTT GAAGGGAACTTGACAACCAAGCCCATCAACGGAGCCATCTTCATCTTCAACCCACGCACAGGGCAGCTGTTCCTCAAGATAATCCACACG TCCGTGTGGGCGGGACAGAAGCGTTTGGGGCAGTTGGCTAAGTGGAAGACAGCTGAGGAGGTGGCCGCCCTGATCCGATCTCTGCCTGTG GAGGAGCAGCCCAAGCAGATCATTGTCACCAGGAAGGGCATGCTGGACCCACTGGAGGTGCACTTACTGGACTTCCCCAATATTGTCATC AAAGGATCGGAGCTCCAACTCCCTTTCCAGGCGTGTCTCAAGGTGGAAAAATTCGGGGATCTCATCCTTAAAGCCACTGAGCCCCAGATG GTTCTCTTCAACCTCTATGACGACTGGCTCAAGACTATTTCATCTTACACGGCCTTCTCCCGTCTCATCCTGATTCTGCGTGCCCTACAT GTGAACAACGATCGGGCAAAAGTGATCCTGAAGCCAGACAAGACTACTATTACAGAACCACACCACATCTGGCCCACTCTGACTGACGAA GAATGGATCAAGGTCGAGGTGCAGCTCAAGGATCTGATCTTGGCTGACTACGGCAAGAAAAACAATGTGAACGTGGCATCACTGACACAA TCAGAAATTCGAGACATCATCCTGGGTATGGAGATCTCGGCACCGTCACAGCAGCGGCAGCAGATCGCTGAGATCGAGAAGCAGACCAAG GAACAATCGCAGCTGACGGCAACACAGACTCGCACTGTCAACAAGCATGGCGATGAGATCATCACCTCCACCACCAGCAACTATGAGACC CAGACTTTCTCATCCAAGACTGAGTGGAGGGTCAGGGCCATCTCTGCTGCCAACCTGCACCTAAGGACCAATCACATCTATGTTTCATCT GACGACATCAAGGAGACTGGCTACACCTACATCCTTCCCAAGAATGTGCTTAAGAAGTTCATCTGCATATCTGACCTTCGGGCCCAAATT GCAGGATACCTATATGGGGTGAGCCCACCAGATAACCCCCAGGTGAAGGAGATCCGCTGCATTGTGATGGTGCCGCAGTGGGGCACTCAC CAGACCGTGCACCTGCCTGGCCAGCTGCCCCAGCATGAGTACCTCAAGGAGATGGAACCCTTAGGTTGGATCCACACTCAGCCCAATGAG TCCCCGCAGTTATCACCCCAGGATGTCACCACCCATGCCAAGATCATGGCTGACAACCCATCTTGGGATGGCGAGAAGACCATTATCATC ACATGCAGCTTCACGCCAGGCTCCTGTACACTGACGGCCTACAAGCTGACCCCCAGTGGCTACGAATGGGGCCGCCAGAACACAGACAAG GGCAACAACCCCAAGGGCTACCTGCCTTCACACTATGAGAGGGTGCAGATGCTGCTGTCGGACCGTTTCCTTGGCTTCTTCATGGTCCCT GCCCAGTCCTCGTGGAACTACAACTTCATGGGTGTTCGGCATGACCCCAACATGAAATATGAGCTACAGCTGGCGAACCCCAAAGAGTTC TACCACGAGGTGCACAGGCCCTCTCACTTCCTCAACTTTGCTCTCCTGCAGGAGGGGGAGGTTTACTCTGCGGATCGGGAGGACCTGTAT >In-frame_PITPNA_ENST00000539476_chr17_1444860_-_PRPF8_ENST00000304992_chr17_1565447_-_3606nt ATGGTGCTGCTCAAGGAGTATCGAGTAATCCTGCCTGTGTCTGTAGATGAGTATCAAGTGGGGCAGCTGTATTCTGTGGCTGAGGCCAGT AAAAATGAAACGGGTGGTGGCGAAGGCGTGGAGGTCCTGGTGAATGAGCCCTACGAGAAGGACGGTGAGAAAGGCCAGTACACACACAAG ATCTACCACCTGCAGAGCAAAGTACCCACGTTTGTTCGAATGCTGGCCCCAGAGGGAGCCCTGAATATACACGAGAAAGCCTGGAATGCT TACCCCTACTGCAGAACCGTTCTTCCAAATGAGTACATGAAAGAAGACTTTCTGATTAAAATTGAAACCTGGCACAAACCAGATCTTGGC ACGCAGGAGAATATTGTGAATAAGTGGAATACAGCTCTCATTGGCCTTATGACATACTTTCGGGAGGCTGTGGTGAACACCCAAGAGCTC TTGGACTTACTGGTGAAGTGTGAGAACAAAATCCAGACACGTATCAAGATTGGACTCAACTCCAAGATGCCAAGTCGGTTCCCCCCGGTT GTGTTCTACACCCCTAAGGAGTTGGGTGGACTCGGCATGCTCTCAATGGGCCATGTGCTCATCCCCCAATCCGACCTCAGGTGGTCCAAA CAGACAGATGTAGGTATCACACACTTTCGTTCAGGAATGAGCCATGAAGAAGACCAGCTCATTCCCAACTTGTACCGCTACATACAGCCA TGGGAGAGCGAGTTCATTGATTCTCAGCGGGTCTGGGCTGAGTACGCACTCAAGAGGCAAGAGGCCATTGCTCAGAACAGACGCCTGACT TTAGAAGACCTAGAAGATTCATGGGATCGTGGCATTCCTCGAATCAATACCCTCTTCCAGAAGGACCGGCACACACTGGCTTATGATAAG GGCTGGCGTGTCAGAACTGACTTTAAGCAGTATCAGGTTTTGAAGCAGAATCCGTTCTGGTGGACACACCAGCGGCATGATGGGAAGCTC TGGAACCTGAACAACTACCGTACAGACATGATCCAGGCCCTGGGCGGTGTGGAAGGCATTCTGGAACACACACTCTTTAAGGGCACTTAC TTCCCTACCTGGGAGGGGCTTTTCTGGGAGAAGGCCAGTGGCTTTGAGGAATCTATGAAGTGGAAGAAGCTAACTAATGCTCAGCGATCA GGACTGAACCAGATTCCCAATCGTAGATTCACCCTCTGGTGGTCCCCGACCATTAATCGAGCCAATGTATATGTAGGCTTTCAGGTGCAG CTAGACCTGACGGGTATCTTCATGCACGGCAAGATCCCCACGCTGAAGATCTCTCTCATCCAGATCTTCCGAGCTCACTTGTGGCAGAAG ATCCATGAGAGCATTGTTATGGACTTATGTCAGGTGTTTGACCAGGAACTTGATGCACTGGAAATTGAGACAGTACAAAAGGAGACAATC CATCCCCGAAAGTCATATAAGATGAACTCTTCCTGTGCAGATATCCTGCTCTTTGCCTCCTATAAGTGGAATGTCTCCCGGCCCTCATTG CTGGCTGACTCCAAGGATGTGATGGACAGCACCACCACCCAGAAATACTGGATTGACATCCAGTTGCGCTGGGGGGACTATGATTCCCAC GACATTGAGCGCTACGCCCGGGCCAAGTTCCTGGACTACACCACCGACAACATGAGTATCTACCCTTCGCCCACAGGTGTACTCATCGCC ATTGACCTGGCCTATAACTTGCACAGTGCCTATGGAAACTGGTTCCCAGGCAGCAAGCCTCTCATACAACAGGCCATGGCCAAGATCATG AAGGCAAACCCTGCCCTGTATGTGTTACGTGAACGGATCCGCAAGGGGCTACAGCTCTATTCATCTGAACCCACTGAGCCTTATTTGTCT TCTCAGAACTATGGTGAGCTCTTCTCCAACCAGATTATCTGGTTTGTGGATGACACCAACGTCTACAGAGTGACTATTCACAAGACCTTT GAAGGGAACTTGACAACCAAGCCCATCAACGGAGCCATCTTCATCTTCAACCCACGCACAGGGCAGCTGTTCCTCAAGATAATCCACACG TCCGTGTGGGCGGGACAGAAGCGTTTGGGGCAGTTGGCTAAGTGGAAGACAGCTGAGGAGGTGGCCGCCCTGATCCGATCTCTGCCTGTG GAGGAGCAGCCCAAGCAGATCATTGTCACCAGGAAGGGCATGCTGGACCCACTGGAGGTGCACTTACTGGACTTCCCCAATATTGTCATC AAAGGATCGGAGCTCCAACTCCCTTTCCAGGCGTGTCTCAAGGTGGAAAAATTCGGGGATCTCATCCTTAAAGCCACTGAGCCCCAGATG GTTCTCTTCAACCTCTATGACGACTGGCTCAAGACTATTTCATCTTACACGGCCTTCTCCCGTCTCATCCTGATTCTGCGTGCCCTACAT GTGAACAACGATCGGGCAAAAGTGATCCTGAAGCCAGACAAGACTACTATTACAGAACCACACCACATCTGGCCCACTCTGACTGACGAA GAATGGATCAAGGTCGAGGTGCAGCTCAAGGATCTGATCTTGGCTGACTACGGCAAGAAAAACAATGTGAACGTGGCATCACTGACACAA TCAGAAATTCGAGACATCATCCTGGGTATGGAGATCTCGGCACCGTCACAGCAGCGGCAGCAGATCGCTGAGATCGAGAAGCAGACCAAG GAACAATCGCAGCTGACGGCAACACAGACTCGCACTGTCAACAAGCATGGCGATGAGATCATCACCTCCACCACCAGCAACTATGAGACC CAGACTTTCTCATCCAAGACTGAGTGGAGGGTCAGGGCCATCTCTGCTGCCAACCTGCACCTAAGGACCAATCACATCTATGTTTCATCT GACGACATCAAGGAGACTGGCTACACCTACATCCTTCCCAAGAATGTGCTTAAGAAGTTCATCTGCATATCTGACCTTCGGGCCCAAATT GCAGGATACCTATATGGGGTGAGCCCACCAGATAACCCCCAGGTGAAGGAGATCCGCTGCATTGTGATGGTGCCGCAGTGGGGCACTCAC CAGACCGTGCACCTGCCTGGCCAGCTGCCCCAGCATGAGTACCTCAAGGAGATGGAACCCTTAGGTTGGATCCACACTCAGCCCAATGAG TCCCCGCAGTTATCACCCCAGGATGTCACCACCCATGCCAAGATCATGGCTGACAACCCATCTTGGGATGGCGAGAAGACCATTATCATC ACATGCAGCTTCACGCCAGGCTCCTGTACACTGACGGCCTACAAGCTGACCCCCAGTGGCTACGAATGGGGCCGCCAGAACACAGACAAG GGCAACAACCCCAAGGGCTACCTGCCTTCACACTATGAGAGGGTGCAGATGCTGCTGTCGGACCGTTTCCTTGGCTTCTTCATGGTCCCT GCCCAGTCCTCGTGGAACTACAACTTCATGGGTGTTCGGCATGACCCCAACATGAAATATGAGCTACAGCTGGCGAACCCCAAAGAGTTC TACCACGAGGTGCACAGGCCCTCTCACTTCCTCAACTTTGCTCTCCTGCAGGAGGGGGAGGTTTACTCTGCGGATCGGGAGGACCTGTAT >In-frame_PITPNA_ENST00000539476_chr17_1444860_-_PRPF8_ENST00000572621_chr17_1565447_-_3606nt ATGGTGCTGCTCAAGGAGTATCGAGTAATCCTGCCTGTGTCTGTAGATGAGTATCAAGTGGGGCAGCTGTATTCTGTGGCTGAGGCCAGT AAAAATGAAACGGGTGGTGGCGAAGGCGTGGAGGTCCTGGTGAATGAGCCCTACGAGAAGGACGGTGAGAAAGGCCAGTACACACACAAG ATCTACCACCTGCAGAGCAAAGTACCCACGTTTGTTCGAATGCTGGCCCCAGAGGGAGCCCTGAATATACACGAGAAAGCCTGGAATGCT TACCCCTACTGCAGAACCGTTCTTCCAAATGAGTACATGAAAGAAGACTTTCTGATTAAAATTGAAACCTGGCACAAACCAGATCTTGGC ACGCAGGAGAATATTGTGAATAAGTGGAATACAGCTCTCATTGGCCTTATGACATACTTTCGGGAGGCTGTGGTGAACACCCAAGAGCTC TTGGACTTACTGGTGAAGTGTGAGAACAAAATCCAGACACGTATCAAGATTGGACTCAACTCCAAGATGCCAAGTCGGTTCCCCCCGGTT GTGTTCTACACCCCTAAGGAGTTGGGTGGACTCGGCATGCTCTCAATGGGCCATGTGCTCATCCCCCAATCCGACCTCAGGTGGTCCAAA CAGACAGATGTAGGTATCACACACTTTCGTTCAGGAATGAGCCATGAAGAAGACCAGCTCATTCCCAACTTGTACCGCTACATACAGCCA TGGGAGAGCGAGTTCATTGATTCTCAGCGGGTCTGGGCTGAGTACGCACTCAAGAGGCAAGAGGCCATTGCTCAGAACAGACGCCTGACT TTAGAAGACCTAGAAGATTCATGGGATCGTGGCATTCCTCGAATCAATACCCTCTTCCAGAAGGACCGGCACACACTGGCTTATGATAAG GGCTGGCGTGTCAGAACTGACTTTAAGCAGTATCAGGTTTTGAAGCAGAATCCGTTCTGGTGGACACACCAGCGGCATGATGGGAAGCTC TGGAACCTGAACAACTACCGTACAGACATGATCCAGGCCCTGGGCGGTGTGGAAGGCATTCTGGAACACACACTCTTTAAGGGCACTTAC TTCCCTACCTGGGAGGGGCTTTTCTGGGAGAAGGCCAGTGGCTTTGAGGAATCTATGAAGTGGAAGAAGCTAACTAATGCTCAGCGATCA GGACTGAACCAGATTCCCAATCGTAGATTCACCCTCTGGTGGTCCCCGACCATTAATCGAGCCAATGTATATGTAGGCTTTCAGGTGCAG CTAGACCTGACGGGTATCTTCATGCACGGCAAGATCCCCACGCTGAAGATCTCTCTCATCCAGATCTTCCGAGCTCACTTGTGGCAGAAG ATCCATGAGAGCATTGTTATGGACTTATGTCAGGTGTTTGACCAGGAACTTGATGCACTGGAAATTGAGACAGTACAAAAGGAGACAATC CATCCCCGAAAGTCATATAAGATGAACTCTTCCTGTGCAGATATCCTGCTCTTTGCCTCCTATAAGTGGAATGTCTCCCGGCCCTCATTG CTGGCTGACTCCAAGGATGTGATGGACAGCACCACCACCCAGAAATACTGGATTGACATCCAGTTGCGCTGGGGGGACTATGATTCCCAC GACATTGAGCGCTACGCCCGGGCCAAGTTCCTGGACTACACCACCGACAACATGAGTATCTACCCTTCGCCCACAGGTGTACTCATCGCC ATTGACCTGGCCTATAACTTGCACAGTGCCTATGGAAACTGGTTCCCAGGCAGCAAGCCTCTCATACAACAGGCCATGGCCAAGATCATG AAGGCAAACCCTGCCCTGTATGTGTTACGTGAACGGATCCGCAAGGGGCTACAGCTCTATTCATCTGAACCCACTGAGCCTTATTTGTCT TCTCAGAACTATGGTGAGCTCTTCTCCAACCAGATTATCTGGTTTGTGGATGACACCAACGTCTACAGAGTGACTATTCACAAGACCTTT GAAGGGAACTTGACAACCAAGCCCATCAACGGAGCCATCTTCATCTTCAACCCACGCACAGGGCAGCTGTTCCTCAAGATAATCCACACG TCCGTGTGGGCGGGACAGAAGCGTTTGGGGCAGTTGGCTAAGTGGAAGACAGCTGAGGAGGTGGCCGCCCTGATCCGATCTCTGCCTGTG GAGGAGCAGCCCAAGCAGATCATTGTCACCAGGAAGGGCATGCTGGACCCACTGGAGGTGCACTTACTGGACTTCCCCAATATTGTCATC AAAGGATCGGAGCTCCAACTCCCTTTCCAGGCGTGTCTCAAGGTGGAAAAATTCGGGGATCTCATCCTTAAAGCCACTGAGCCCCAGATG GTTCTCTTCAACCTCTATGACGACTGGCTCAAGACTATTTCATCTTACACGGCCTTCTCCCGTCTCATCCTGATTCTGCGTGCCCTACAT GTGAACAACGATCGGGCAAAAGTGATCCTGAAGCCAGACAAGACTACTATTACAGAACCACACCACATCTGGCCCACTCTGACTGACGAA GAATGGATCAAGGTCGAGGTGCAGCTCAAGGATCTGATCTTGGCTGACTACGGCAAGAAAAACAATGTGAACGTGGCATCACTGACACAA TCAGAAATTCGAGACATCATCCTGGGTATGGAGATCTCGGCACCGTCACAGCAGCGGCAGCAGATCGCTGAGATCGAGAAGCAGACCAAG GAACAATCGCAGCTGACGGCAACACAGACTCGCACTGTCAACAAGCATGGCGATGAGATCATCACCTCCACCACCAGCAACTATGAGACC CAGACTTTCTCATCCAAGACTGAGTGGAGGGTCAGGGCCATCTCTGCTGCCAACCTGCACCTAAGGACCAATCACATCTATGTTTCATCT GACGACATCAAGGAGACTGGCTACACCTACATCCTTCCCAAGAATGTGCTTAAGAAGTTCATCTGCATATCTGACCTTCGGGCCCAAATT GCAGGATACCTATATGGGGTGAGCCCACCAGATAACCCCCAGGTGAAGGAGATCCGCTGCATTGTGATGGTGCCGCAGTGGGGCACTCAC CAGACCGTGCACCTGCCTGGCCAGCTGCCCCAGCATGAGTACCTCAAGGAGATGGAACCCTTAGGTTGGATCCACACTCAGCCCAATGAG TCCCCGCAGTTATCACCCCAGGATGTCACCACCCATGCCAAGATCATGGCTGACAACCCATCTTGGGATGGCGAGAAGACCATTATCATC ACATGCAGCTTCACGCCAGGCTCCTGTACACTGACGGCCTACAAGCTGACCCCCAGTGGCTACGAATGGGGCCGCCAGAACACAGACAAG GGCAACAACCCCAAGGGCTACCTGCCTTCACACTATGAGAGGGTGCAGATGCTGCTGTCGGACCGTTTCCTTGGCTTCTTCATGGTCCCT GCCCAGTCCTCGTGGAACTACAACTTCATGGGTGTTCGGCATGACCCCAACATGAAATATGAGCTACAGCTGGCGAACCCCAAAGAGTTC TACCACGAGGTGCACAGGCCCTCTCACTTCCTCAACTTTGCTCTCCTGCAGGAGGGGGAGGTTTACTCTGCGGATCGGGAGGACCTGTAT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_PITPNA_ENST00000313486_chr17_1444860_-_PRPF8_ENST00000304992_chr17_1565447_-_4035nt TTGCCGCAGAGACGCCCCGCCCCCGCGCGGCGCTGCGGAACCGGAGCTCCGGGCGGCGTCGGCAGCGGCGCGAGAGGCGACGAGGCCCGG GCGGCAGGAGCCGGCGCGGCGACCGCGGCGAGGGCGGCGGGGACGGAGCAGAGCACGACGAAGACGCACAGGCAGCCGGGCCGGGCCGGG CCACGGGGAGAGCGGCCGGCGGGCAGCGGGCGGGAGGCCGGGCGGGCCGCGGGCAGCCACCGAGCCGCGAAGCGACATGGTGCTGCTCAA GGAGTATCGAGTAATCCTGCCTGTGTCTGTAGATGAGTATCAAGTGGGGCAGCTGTATTCTGTGGCTGAGGCCAGTAAAAATGAAACGGG TGGTGGCGAAGGCGTGGAGGTCCTGGTGAATGAGCCCTACGAGAAGGACGGTGAGAAAGGCCAGTACACACACAAGATCTACCACCTGCA GAGCAAAGTACCCACGTTTGTTCGAATGCTGGCCCCAGAGGGAGCCCTGAATATACACGAGAAAGCCTGGAATGCTTACCCCTACTGCAG AACCGTTATTACAAATGAGTACATGAAAGAAGACTTTCTGATTAAAATTGAAACCTGGCACAAACCAGATCTTGGCACGCAGGAGAATAT TGTGAATAAGTGGAATACAGCTCTCATTGGCCTTATGACATACTTTCGGGAGGCTGTGGTGAACACCCAAGAGCTCTTGGACTTACTGGT GAAGTGTGAGAACAAAATCCAGACACGTATCAAGATTGGACTCAACTCCAAGATGCCAAGTCGGTTCCCCCCGGTTGTGTTCTACACCCC TAAGGAGTTGGGTGGACTCGGCATGCTCTCAATGGGCCATGTGCTCATCCCCCAATCCGACCTCAGGTGGTCCAAACAGACAGATGTAGG TATCACACACTTTCGTTCAGGAATGAGCCATGAAGAAGACCAGCTCATTCCCAACTTGTACCGCTACATACAGCCATGGGAGAGCGAGTT CATTGATTCTCAGCGGGTCTGGGCTGAGTACGCACTCAAGAGGCAAGAGGCCATTGCTCAGAACAGACGCCTGACTTTAGAAGACCTAGA AGATTCATGGGATCGTGGCATTCCTCGAATCAATACCCTCTTCCAGAAGGACCGGCACACACTGGCTTATGATAAGGGCTGGCGTGTCAG AACTGACTTTAAGCAGTATCAGGTTTTGAAGCAGAATCCGTTCTGGTGGACACACCAGCGGCATGATGGGAAGCTCTGGAACCTGAACAA CTACCGTACAGACATGATCCAGGCCCTGGGCGGTGTGGAAGGCATTCTGGAACACACACTCTTTAAGGGCACTTACTTCCCTACCTGGGA GGGGCTTTTCTGGGAGAAGGCCAGTGGCTTTGAGGAATCTATGAAGTGGAAGAAGCTAACTAATGCTCAGCGATCAGGACTGAACCAGAT TCCCAATCGTAGATTCACCCTCTGGTGGTCCCCGACCATTAATCGAGCCAATGTATATGTAGGCTTTCAGGTGCAGCTAGACCTGACGGG TATCTTCATGCACGGCAAGATCCCCACGCTGAAGATCTCTCTCATCCAGATCTTCCGAGCTCACTTGTGGCAGAAGATCCATGAGAGCAT TGTTATGGACTTATGTCAGGTGTTTGACCAGGAACTTGATGCACTGGAAATTGAGACAGTACAAAAGGAGACAATCCATCCCCGAAAGTC ATATAAGATGAACTCTTCCTGTGCAGATATCCTGCTCTTTGCCTCCTATAAGTGGAATGTCTCCCGGCCCTCATTGCTGGCTGACTCCAA GGATGTGATGGACAGCACCACCACCCAGAAATACTGGATTGACATCCAGTTGCGCTGGGGGGACTATGATTCCCACGACATTGAGCGCTA CGCCCGGGCCAAGTTCCTGGACTACACCACCGACAACATGAGTATCTACCCTTCGCCCACAGGTGTACTCATCGCCATTGACCTGGCCTA TAACTTGCACAGTGCCTATGGAAACTGGTTCCCAGGCAGCAAGCCTCTCATACAACAGGCCATGGCCAAGATCATGAAGGCAAACCCTGC CCTGTATGTGTTACGTGAACGGATCCGCAAGGGGCTACAGCTCTATTCATCTGAACCCACTGAGCCTTATTTGTCTTCTCAGAACTATGG TGAGCTCTTCTCCAACCAGATTATCTGGTTTGTGGATGACACCAACGTCTACAGAGTGACTATTCACAAGACCTTTGAAGGGAACTTGAC AACCAAGCCCATCAACGGAGCCATCTTCATCTTCAACCCACGCACAGGGCAGCTGTTCCTCAAGATAATCCACACGTCCGTGTGGGCGGG ACAGAAGCGTTTGGGGCAGTTGGCTAAGTGGAAGACAGCTGAGGAGGTGGCCGCCCTGATCCGATCTCTGCCTGTGGAGGAGCAGCCCAA GCAGATCATTGTCACCAGGAAGGGCATGCTGGACCCACTGGAGGTGCACTTACTGGACTTCCCCAATATTGTCATCAAAGGATCGGAGCT CCAACTCCCTTTCCAGGCGTGTCTCAAGGTGGAAAAATTCGGGGATCTCATCCTTAAAGCCACTGAGCCCCAGATGGTTCTCTTCAACCT CTATGACGACTGGCTCAAGACTATTTCATCTTACACGGCCTTCTCCCGTCTCATCCTGATTCTGCGTGCCCTACATGTGAACAACGATCG GGCAAAAGTGATCCTGAAGCCAGACAAGACTACTATTACAGAACCACACCACATCTGGCCCACTCTGACTGACGAAGAATGGATCAAGGT CGAGGTGCAGCTCAAGGATCTGATCTTGGCTGACTACGGCAAGAAAAACAATGTGAACGTGGCATCACTGACACAATCAGAAATTCGAGA CATCATCCTGGGTATGGAGATCTCGGCACCGTCACAGCAGCGGCAGCAGATCGCTGAGATCGAGAAGCAGACCAAGGAACAATCGCAGCT GACGGCAACACAGACTCGCACTGTCAACAAGCATGGCGATGAGATCATCACCTCCACCACCAGCAACTATGAGACCCAGACTTTCTCATC CAAGACTGAGTGGAGGGTCAGGGCCATCTCTGCTGCCAACCTGCACCTAAGGACCAATCACATCTATGTTTCATCTGACGACATCAAGGA GACTGGCTACACCTACATCCTTCCCAAGAATGTGCTTAAGAAGTTCATCTGCATATCTGACCTTCGGGCCCAAATTGCAGGATACCTATA TGGGGTGAGCCCACCAGATAACCCCCAGGTGAAGGAGATCCGCTGCATTGTGATGGTGCCGCAGTGGGGCACTCACCAGACCGTGCACCT GCCTGGCCAGCTGCCCCAGCATGAGTACCTCAAGGAGATGGAACCCTTAGGTTGGATCCACACTCAGCCCAATGAGTCCCCGCAGTTATC ACCCCAGGATGTCACCACCCATGCCAAGATCATGGCTGACAACCCATCTTGGGATGGCGAGAAGACCATTATCATCACATGCAGCTTCAC GCCAGGCTCCTGTACACTGACGGCCTACAAGCTGACCCCCAGTGGCTACGAATGGGGCCGCCAGAACACAGACAAGGGCAACAACCCCAA GGGCTACCTGCCTTCACACTATGAGAGGGTGCAGATGCTGCTGTCGGACCGTTTCCTTGGCTTCTTCATGGTCCCTGCCCAGTCCTCGTG GAACTACAACTTCATGGGTGTTCGGCATGACCCCAACATGAAATATGAGCTACAGCTGGCGAACCCCAAAGAGTTCTACCACGAGGTGCA CAGGCCCTCTCACTTCCTCAACTTTGCTCTCCTGCAGGAGGGGGAGGTTTACTCTGCGGATCGGGAGGACCTGTATGCCTGACCGTTTCC CTGCCTCCTGCTTCAGCCTCCCGAGGCCGAAGCCTCAGCCCCTCCAGACAGGCCGCTGACATTCAGCAGTTTGGCCTCTTTCCCTCTGTC >In-frame_PITPNA_ENST00000313486_chr17_1444860_-_PRPF8_ENST00000572621_chr17_1565447_-_4033nt TTGCCGCAGAGACGCCCCGCCCCCGCGCGGCGCTGCGGAACCGGAGCTCCGGGCGGCGTCGGCAGCGGCGCGAGAGGCGACGAGGCCCGG GCGGCAGGAGCCGGCGCGGCGACCGCGGCGAGGGCGGCGGGGACGGAGCAGAGCACGACGAAGACGCACAGGCAGCCGGGCCGGGCCGGG CCACGGGGAGAGCGGCCGGCGGGCAGCGGGCGGGAGGCCGGGCGGGCCGCGGGCAGCCACCGAGCCGCGAAGCGACATGGTGCTGCTCAA GGAGTATCGAGTAATCCTGCCTGTGTCTGTAGATGAGTATCAAGTGGGGCAGCTGTATTCTGTGGCTGAGGCCAGTAAAAATGAAACGGG TGGTGGCGAAGGCGTGGAGGTCCTGGTGAATGAGCCCTACGAGAAGGACGGTGAGAAAGGCCAGTACACACACAAGATCTACCACCTGCA GAGCAAAGTACCCACGTTTGTTCGAATGCTGGCCCCAGAGGGAGCCCTGAATATACACGAGAAAGCCTGGAATGCTTACCCCTACTGCAG AACCGTTATTACAAATGAGTACATGAAAGAAGACTTTCTGATTAAAATTGAAACCTGGCACAAACCAGATCTTGGCACGCAGGAGAATAT TGTGAATAAGTGGAATACAGCTCTCATTGGCCTTATGACATACTTTCGGGAGGCTGTGGTGAACACCCAAGAGCTCTTGGACTTACTGGT GAAGTGTGAGAACAAAATCCAGACACGTATCAAGATTGGACTCAACTCCAAGATGCCAAGTCGGTTCCCCCCGGTTGTGTTCTACACCCC TAAGGAGTTGGGTGGACTCGGCATGCTCTCAATGGGCCATGTGCTCATCCCCCAATCCGACCTCAGGTGGTCCAAACAGACAGATGTAGG TATCACACACTTTCGTTCAGGAATGAGCCATGAAGAAGACCAGCTCATTCCCAACTTGTACCGCTACATACAGCCATGGGAGAGCGAGTT CATTGATTCTCAGCGGGTCTGGGCTGAGTACGCACTCAAGAGGCAAGAGGCCATTGCTCAGAACAGACGCCTGACTTTAGAAGACCTAGA AGATTCATGGGATCGTGGCATTCCTCGAATCAATACCCTCTTCCAGAAGGACCGGCACACACTGGCTTATGATAAGGGCTGGCGTGTCAG AACTGACTTTAAGCAGTATCAGGTTTTGAAGCAGAATCCGTTCTGGTGGACACACCAGCGGCATGATGGGAAGCTCTGGAACCTGAACAA CTACCGTACAGACATGATCCAGGCCCTGGGCGGTGTGGAAGGCATTCTGGAACACACACTCTTTAAGGGCACTTACTTCCCTACCTGGGA GGGGCTTTTCTGGGAGAAGGCCAGTGGCTTTGAGGAATCTATGAAGTGGAAGAAGCTAACTAATGCTCAGCGATCAGGACTGAACCAGAT TCCCAATCGTAGATTCACCCTCTGGTGGTCCCCGACCATTAATCGAGCCAATGTATATGTAGGCTTTCAGGTGCAGCTAGACCTGACGGG TATCTTCATGCACGGCAAGATCCCCACGCTGAAGATCTCTCTCATCCAGATCTTCCGAGCTCACTTGTGGCAGAAGATCCATGAGAGCAT TGTTATGGACTTATGTCAGGTGTTTGACCAGGAACTTGATGCACTGGAAATTGAGACAGTACAAAAGGAGACAATCCATCCCCGAAAGTC ATATAAGATGAACTCTTCCTGTGCAGATATCCTGCTCTTTGCCTCCTATAAGTGGAATGTCTCCCGGCCCTCATTGCTGGCTGACTCCAA GGATGTGATGGACAGCACCACCACCCAGAAATACTGGATTGACATCCAGTTGCGCTGGGGGGACTATGATTCCCACGACATTGAGCGCTA CGCCCGGGCCAAGTTCCTGGACTACACCACCGACAACATGAGTATCTACCCTTCGCCCACAGGTGTACTCATCGCCATTGACCTGGCCTA TAACTTGCACAGTGCCTATGGAAACTGGTTCCCAGGCAGCAAGCCTCTCATACAACAGGCCATGGCCAAGATCATGAAGGCAAACCCTGC CCTGTATGTGTTACGTGAACGGATCCGCAAGGGGCTACAGCTCTATTCATCTGAACCCACTGAGCCTTATTTGTCTTCTCAGAACTATGG TGAGCTCTTCTCCAACCAGATTATCTGGTTTGTGGATGACACCAACGTCTACAGAGTGACTATTCACAAGACCTTTGAAGGGAACTTGAC AACCAAGCCCATCAACGGAGCCATCTTCATCTTCAACCCACGCACAGGGCAGCTGTTCCTCAAGATAATCCACACGTCCGTGTGGGCGGG ACAGAAGCGTTTGGGGCAGTTGGCTAAGTGGAAGACAGCTGAGGAGGTGGCCGCCCTGATCCGATCTCTGCCTGTGGAGGAGCAGCCCAA GCAGATCATTGTCACCAGGAAGGGCATGCTGGACCCACTGGAGGTGCACTTACTGGACTTCCCCAATATTGTCATCAAAGGATCGGAGCT CCAACTCCCTTTCCAGGCGTGTCTCAAGGTGGAAAAATTCGGGGATCTCATCCTTAAAGCCACTGAGCCCCAGATGGTTCTCTTCAACCT CTATGACGACTGGCTCAAGACTATTTCATCTTACACGGCCTTCTCCCGTCTCATCCTGATTCTGCGTGCCCTACATGTGAACAACGATCG GGCAAAAGTGATCCTGAAGCCAGACAAGACTACTATTACAGAACCACACCACATCTGGCCCACTCTGACTGACGAAGAATGGATCAAGGT CGAGGTGCAGCTCAAGGATCTGATCTTGGCTGACTACGGCAAGAAAAACAATGTGAACGTGGCATCACTGACACAATCAGAAATTCGAGA CATCATCCTGGGTATGGAGATCTCGGCACCGTCACAGCAGCGGCAGCAGATCGCTGAGATCGAGAAGCAGACCAAGGAACAATCGCAGCT GACGGCAACACAGACTCGCACTGTCAACAAGCATGGCGATGAGATCATCACCTCCACCACCAGCAACTATGAGACCCAGACTTTCTCATC CAAGACTGAGTGGAGGGTCAGGGCCATCTCTGCTGCCAACCTGCACCTAAGGACCAATCACATCTATGTTTCATCTGACGACATCAAGGA GACTGGCTACACCTACATCCTTCCCAAGAATGTGCTTAAGAAGTTCATCTGCATATCTGACCTTCGGGCCCAAATTGCAGGATACCTATA TGGGGTGAGCCCACCAGATAACCCCCAGGTGAAGGAGATCCGCTGCATTGTGATGGTGCCGCAGTGGGGCACTCACCAGACCGTGCACCT GCCTGGCCAGCTGCCCCAGCATGAGTACCTCAAGGAGATGGAACCCTTAGGTTGGATCCACACTCAGCCCAATGAGTCCCCGCAGTTATC ACCCCAGGATGTCACCACCCATGCCAAGATCATGGCTGACAACCCATCTTGGGATGGCGAGAAGACCATTATCATCACATGCAGCTTCAC GCCAGGCTCCTGTACACTGACGGCCTACAAGCTGACCCCCAGTGGCTACGAATGGGGCCGCCAGAACACAGACAAGGGCAACAACCCCAA GGGCTACCTGCCTTCACACTATGAGAGGGTGCAGATGCTGCTGTCGGACCGTTTCCTTGGCTTCTTCATGGTCCCTGCCCAGTCCTCGTG GAACTACAACTTCATGGGTGTTCGGCATGACCCCAACATGAAATATGAGCTACAGCTGGCGAACCCCAAAGAGTTCTACCACGAGGTGCA CAGGCCCTCTCACTTCCTCAACTTTGCTCTCCTGCAGGAGGGGGAGGTTTACTCTGCGGATCGGGAGGACCTGTATGCCTGACCGTTTCC CTGCCTCCTGCTTCAGCCTCCCGAGGCCGAAGCCTCAGCCCCTCCAGACAGGCCGCTGACATTCAGCAGTTTGGCCTCTTTCCCTCTGTC >In-frame_PITPNA_ENST00000539476_chr17_1444860_-_PRPF8_ENST00000304992_chr17_1565447_-_4035nt TTGCCGCAGAGACGCCCCGCCCCCGCGCGGCGCTGCGGAACCGGAGCTCCGGGCGGCGTCGGCAGCGGCGCGAGAGGCGACGAGGCCCGG GCGGCAGGAGCCGGCGCGGCGACCGCGGCGAGGGCGGCGGGGACGGAGCAGAGCACGACGAAGACGCACAGGCAGCCGGGCCGGGCCGGG CCACGGGGAGAGCGGCCGGCGGGCAGCGGGCGGGAGGCCGGGCGGGCCGCGGGCAGCCACCGAGCCGCGAAGCGACATGGTGCTGCTCAA GGAGTATCGAGTAATCCTGCCTGTGTCTGTAGATGAGTATCAAGTGGGGCAGCTGTATTCTGTGGCTGAGGCCAGTAAAAATGAAACGGG TGGTGGCGAAGGCGTGGAGGTCCTGGTGAATGAGCCCTACGAGAAGGACGGTGAGAAAGGCCAGTACACACACAAGATCTACCACCTGCA GAGCAAAGTACCCACGTTTGTTCGAATGCTGGCCCCAGAGGGAGCCCTGAATATACACGAGAAAGCCTGGAATGCTTACCCCTACTGCAG AACCGTTCTTCCAAATGAGTACATGAAAGAAGACTTTCTGATTAAAATTGAAACCTGGCACAAACCAGATCTTGGCACGCAGGAGAATAT TGTGAATAAGTGGAATACAGCTCTCATTGGCCTTATGACATACTTTCGGGAGGCTGTGGTGAACACCCAAGAGCTCTTGGACTTACTGGT GAAGTGTGAGAACAAAATCCAGACACGTATCAAGATTGGACTCAACTCCAAGATGCCAAGTCGGTTCCCCCCGGTTGTGTTCTACACCCC TAAGGAGTTGGGTGGACTCGGCATGCTCTCAATGGGCCATGTGCTCATCCCCCAATCCGACCTCAGGTGGTCCAAACAGACAGATGTAGG TATCACACACTTTCGTTCAGGAATGAGCCATGAAGAAGACCAGCTCATTCCCAACTTGTACCGCTACATACAGCCATGGGAGAGCGAGTT CATTGATTCTCAGCGGGTCTGGGCTGAGTACGCACTCAAGAGGCAAGAGGCCATTGCTCAGAACAGACGCCTGACTTTAGAAGACCTAGA AGATTCATGGGATCGTGGCATTCCTCGAATCAATACCCTCTTCCAGAAGGACCGGCACACACTGGCTTATGATAAGGGCTGGCGTGTCAG AACTGACTTTAAGCAGTATCAGGTTTTGAAGCAGAATCCGTTCTGGTGGACACACCAGCGGCATGATGGGAAGCTCTGGAACCTGAACAA CTACCGTACAGACATGATCCAGGCCCTGGGCGGTGTGGAAGGCATTCTGGAACACACACTCTTTAAGGGCACTTACTTCCCTACCTGGGA GGGGCTTTTCTGGGAGAAGGCCAGTGGCTTTGAGGAATCTATGAAGTGGAAGAAGCTAACTAATGCTCAGCGATCAGGACTGAACCAGAT TCCCAATCGTAGATTCACCCTCTGGTGGTCCCCGACCATTAATCGAGCCAATGTATATGTAGGCTTTCAGGTGCAGCTAGACCTGACGGG TATCTTCATGCACGGCAAGATCCCCACGCTGAAGATCTCTCTCATCCAGATCTTCCGAGCTCACTTGTGGCAGAAGATCCATGAGAGCAT TGTTATGGACTTATGTCAGGTGTTTGACCAGGAACTTGATGCACTGGAAATTGAGACAGTACAAAAGGAGACAATCCATCCCCGAAAGTC ATATAAGATGAACTCTTCCTGTGCAGATATCCTGCTCTTTGCCTCCTATAAGTGGAATGTCTCCCGGCCCTCATTGCTGGCTGACTCCAA GGATGTGATGGACAGCACCACCACCCAGAAATACTGGATTGACATCCAGTTGCGCTGGGGGGACTATGATTCCCACGACATTGAGCGCTA CGCCCGGGCCAAGTTCCTGGACTACACCACCGACAACATGAGTATCTACCCTTCGCCCACAGGTGTACTCATCGCCATTGACCTGGCCTA TAACTTGCACAGTGCCTATGGAAACTGGTTCCCAGGCAGCAAGCCTCTCATACAACAGGCCATGGCCAAGATCATGAAGGCAAACCCTGC CCTGTATGTGTTACGTGAACGGATCCGCAAGGGGCTACAGCTCTATTCATCTGAACCCACTGAGCCTTATTTGTCTTCTCAGAACTATGG TGAGCTCTTCTCCAACCAGATTATCTGGTTTGTGGATGACACCAACGTCTACAGAGTGACTATTCACAAGACCTTTGAAGGGAACTTGAC AACCAAGCCCATCAACGGAGCCATCTTCATCTTCAACCCACGCACAGGGCAGCTGTTCCTCAAGATAATCCACACGTCCGTGTGGGCGGG ACAGAAGCGTTTGGGGCAGTTGGCTAAGTGGAAGACAGCTGAGGAGGTGGCCGCCCTGATCCGATCTCTGCCTGTGGAGGAGCAGCCCAA GCAGATCATTGTCACCAGGAAGGGCATGCTGGACCCACTGGAGGTGCACTTACTGGACTTCCCCAATATTGTCATCAAAGGATCGGAGCT CCAACTCCCTTTCCAGGCGTGTCTCAAGGTGGAAAAATTCGGGGATCTCATCCTTAAAGCCACTGAGCCCCAGATGGTTCTCTTCAACCT CTATGACGACTGGCTCAAGACTATTTCATCTTACACGGCCTTCTCCCGTCTCATCCTGATTCTGCGTGCCCTACATGTGAACAACGATCG GGCAAAAGTGATCCTGAAGCCAGACAAGACTACTATTACAGAACCACACCACATCTGGCCCACTCTGACTGACGAAGAATGGATCAAGGT CGAGGTGCAGCTCAAGGATCTGATCTTGGCTGACTACGGCAAGAAAAACAATGTGAACGTGGCATCACTGACACAATCAGAAATTCGAGA CATCATCCTGGGTATGGAGATCTCGGCACCGTCACAGCAGCGGCAGCAGATCGCTGAGATCGAGAAGCAGACCAAGGAACAATCGCAGCT GACGGCAACACAGACTCGCACTGTCAACAAGCATGGCGATGAGATCATCACCTCCACCACCAGCAACTATGAGACCCAGACTTTCTCATC CAAGACTGAGTGGAGGGTCAGGGCCATCTCTGCTGCCAACCTGCACCTAAGGACCAATCACATCTATGTTTCATCTGACGACATCAAGGA GACTGGCTACACCTACATCCTTCCCAAGAATGTGCTTAAGAAGTTCATCTGCATATCTGACCTTCGGGCCCAAATTGCAGGATACCTATA TGGGGTGAGCCCACCAGATAACCCCCAGGTGAAGGAGATCCGCTGCATTGTGATGGTGCCGCAGTGGGGCACTCACCAGACCGTGCACCT GCCTGGCCAGCTGCCCCAGCATGAGTACCTCAAGGAGATGGAACCCTTAGGTTGGATCCACACTCAGCCCAATGAGTCCCCGCAGTTATC ACCCCAGGATGTCACCACCCATGCCAAGATCATGGCTGACAACCCATCTTGGGATGGCGAGAAGACCATTATCATCACATGCAGCTTCAC GCCAGGCTCCTGTACACTGACGGCCTACAAGCTGACCCCCAGTGGCTACGAATGGGGCCGCCAGAACACAGACAAGGGCAACAACCCCAA GGGCTACCTGCCTTCACACTATGAGAGGGTGCAGATGCTGCTGTCGGACCGTTTCCTTGGCTTCTTCATGGTCCCTGCCCAGTCCTCGTG GAACTACAACTTCATGGGTGTTCGGCATGACCCCAACATGAAATATGAGCTACAGCTGGCGAACCCCAAAGAGTTCTACCACGAGGTGCA CAGGCCCTCTCACTTCCTCAACTTTGCTCTCCTGCAGGAGGGGGAGGTTTACTCTGCGGATCGGGAGGACCTGTATGCCTGACCGTTTCC CTGCCTCCTGCTTCAGCCTCCCGAGGCCGAAGCCTCAGCCCCTCCAGACAGGCCGCTGACATTCAGCAGTTTGGCCTCTTTCCCTCTGTC >In-frame_PITPNA_ENST00000539476_chr17_1444860_-_PRPF8_ENST00000572621_chr17_1565447_-_4033nt TTGCCGCAGAGACGCCCCGCCCCCGCGCGGCGCTGCGGAACCGGAGCTCCGGGCGGCGTCGGCAGCGGCGCGAGAGGCGACGAGGCCCGG GCGGCAGGAGCCGGCGCGGCGACCGCGGCGAGGGCGGCGGGGACGGAGCAGAGCACGACGAAGACGCACAGGCAGCCGGGCCGGGCCGGG CCACGGGGAGAGCGGCCGGCGGGCAGCGGGCGGGAGGCCGGGCGGGCCGCGGGCAGCCACCGAGCCGCGAAGCGACATGGTGCTGCTCAA GGAGTATCGAGTAATCCTGCCTGTGTCTGTAGATGAGTATCAAGTGGGGCAGCTGTATTCTGTGGCTGAGGCCAGTAAAAATGAAACGGG TGGTGGCGAAGGCGTGGAGGTCCTGGTGAATGAGCCCTACGAGAAGGACGGTGAGAAAGGCCAGTACACACACAAGATCTACCACCTGCA GAGCAAAGTACCCACGTTTGTTCGAATGCTGGCCCCAGAGGGAGCCCTGAATATACACGAGAAAGCCTGGAATGCTTACCCCTACTGCAG AACCGTTCTTCCAAATGAGTACATGAAAGAAGACTTTCTGATTAAAATTGAAACCTGGCACAAACCAGATCTTGGCACGCAGGAGAATAT TGTGAATAAGTGGAATACAGCTCTCATTGGCCTTATGACATACTTTCGGGAGGCTGTGGTGAACACCCAAGAGCTCTTGGACTTACTGGT GAAGTGTGAGAACAAAATCCAGACACGTATCAAGATTGGACTCAACTCCAAGATGCCAAGTCGGTTCCCCCCGGTTGTGTTCTACACCCC TAAGGAGTTGGGTGGACTCGGCATGCTCTCAATGGGCCATGTGCTCATCCCCCAATCCGACCTCAGGTGGTCCAAACAGACAGATGTAGG TATCACACACTTTCGTTCAGGAATGAGCCATGAAGAAGACCAGCTCATTCCCAACTTGTACCGCTACATACAGCCATGGGAGAGCGAGTT CATTGATTCTCAGCGGGTCTGGGCTGAGTACGCACTCAAGAGGCAAGAGGCCATTGCTCAGAACAGACGCCTGACTTTAGAAGACCTAGA AGATTCATGGGATCGTGGCATTCCTCGAATCAATACCCTCTTCCAGAAGGACCGGCACACACTGGCTTATGATAAGGGCTGGCGTGTCAG AACTGACTTTAAGCAGTATCAGGTTTTGAAGCAGAATCCGTTCTGGTGGACACACCAGCGGCATGATGGGAAGCTCTGGAACCTGAACAA CTACCGTACAGACATGATCCAGGCCCTGGGCGGTGTGGAAGGCATTCTGGAACACACACTCTTTAAGGGCACTTACTTCCCTACCTGGGA GGGGCTTTTCTGGGAGAAGGCCAGTGGCTTTGAGGAATCTATGAAGTGGAAGAAGCTAACTAATGCTCAGCGATCAGGACTGAACCAGAT TCCCAATCGTAGATTCACCCTCTGGTGGTCCCCGACCATTAATCGAGCCAATGTATATGTAGGCTTTCAGGTGCAGCTAGACCTGACGGG TATCTTCATGCACGGCAAGATCCCCACGCTGAAGATCTCTCTCATCCAGATCTTCCGAGCTCACTTGTGGCAGAAGATCCATGAGAGCAT TGTTATGGACTTATGTCAGGTGTTTGACCAGGAACTTGATGCACTGGAAATTGAGACAGTACAAAAGGAGACAATCCATCCCCGAAAGTC ATATAAGATGAACTCTTCCTGTGCAGATATCCTGCTCTTTGCCTCCTATAAGTGGAATGTCTCCCGGCCCTCATTGCTGGCTGACTCCAA GGATGTGATGGACAGCACCACCACCCAGAAATACTGGATTGACATCCAGTTGCGCTGGGGGGACTATGATTCCCACGACATTGAGCGCTA CGCCCGGGCCAAGTTCCTGGACTACACCACCGACAACATGAGTATCTACCCTTCGCCCACAGGTGTACTCATCGCCATTGACCTGGCCTA TAACTTGCACAGTGCCTATGGAAACTGGTTCCCAGGCAGCAAGCCTCTCATACAACAGGCCATGGCCAAGATCATGAAGGCAAACCCTGC CCTGTATGTGTTACGTGAACGGATCCGCAAGGGGCTACAGCTCTATTCATCTGAACCCACTGAGCCTTATTTGTCTTCTCAGAACTATGG TGAGCTCTTCTCCAACCAGATTATCTGGTTTGTGGATGACACCAACGTCTACAGAGTGACTATTCACAAGACCTTTGAAGGGAACTTGAC AACCAAGCCCATCAACGGAGCCATCTTCATCTTCAACCCACGCACAGGGCAGCTGTTCCTCAAGATAATCCACACGTCCGTGTGGGCGGG ACAGAAGCGTTTGGGGCAGTTGGCTAAGTGGAAGACAGCTGAGGAGGTGGCCGCCCTGATCCGATCTCTGCCTGTGGAGGAGCAGCCCAA GCAGATCATTGTCACCAGGAAGGGCATGCTGGACCCACTGGAGGTGCACTTACTGGACTTCCCCAATATTGTCATCAAAGGATCGGAGCT CCAACTCCCTTTCCAGGCGTGTCTCAAGGTGGAAAAATTCGGGGATCTCATCCTTAAAGCCACTGAGCCCCAGATGGTTCTCTTCAACCT CTATGACGACTGGCTCAAGACTATTTCATCTTACACGGCCTTCTCCCGTCTCATCCTGATTCTGCGTGCCCTACATGTGAACAACGATCG GGCAAAAGTGATCCTGAAGCCAGACAAGACTACTATTACAGAACCACACCACATCTGGCCCACTCTGACTGACGAAGAATGGATCAAGGT CGAGGTGCAGCTCAAGGATCTGATCTTGGCTGACTACGGCAAGAAAAACAATGTGAACGTGGCATCACTGACACAATCAGAAATTCGAGA CATCATCCTGGGTATGGAGATCTCGGCACCGTCACAGCAGCGGCAGCAGATCGCTGAGATCGAGAAGCAGACCAAGGAACAATCGCAGCT GACGGCAACACAGACTCGCACTGTCAACAAGCATGGCGATGAGATCATCACCTCCACCACCAGCAACTATGAGACCCAGACTTTCTCATC CAAGACTGAGTGGAGGGTCAGGGCCATCTCTGCTGCCAACCTGCACCTAAGGACCAATCACATCTATGTTTCATCTGACGACATCAAGGA GACTGGCTACACCTACATCCTTCCCAAGAATGTGCTTAAGAAGTTCATCTGCATATCTGACCTTCGGGCCCAAATTGCAGGATACCTATA TGGGGTGAGCCCACCAGATAACCCCCAGGTGAAGGAGATCCGCTGCATTGTGATGGTGCCGCAGTGGGGCACTCACCAGACCGTGCACCT GCCTGGCCAGCTGCCCCAGCATGAGTACCTCAAGGAGATGGAACCCTTAGGTTGGATCCACACTCAGCCCAATGAGTCCCCGCAGTTATC ACCCCAGGATGTCACCACCCATGCCAAGATCATGGCTGACAACCCATCTTGGGATGGCGAGAAGACCATTATCATCACATGCAGCTTCAC GCCAGGCTCCTGTACACTGACGGCCTACAAGCTGACCCCCAGTGGCTACGAATGGGGCCGCCAGAACACAGACAAGGGCAACAACCCCAA GGGCTACCTGCCTTCACACTATGAGAGGGTGCAGATGCTGCTGTCGGACCGTTTCCTTGGCTTCTTCATGGTCCCTGCCCAGTCCTCGTG GAACTACAACTTCATGGGTGTTCGGCATGACCCCAACATGAAATATGAGCTACAGCTGGCGAACCCCAAAGAGTTCTACCACGAGGTGCA CAGGCCCTCTCACTTCCTCAACTTTGCTCTCCTGCAGGAGGGGGAGGTTTACTCTGCGGATCGGGAGGACCTGTATGCCTGACCGTTTCC CTGCCTCCTGCTTCAGCCTCCCGAGGCCGAAGCCTCAGCCCCTCCAGACAGGCCGCTGACATTCAGCAGTTTGGCCTCTTTCCCTCTGTC |
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FusionGenePPI for PITPNA_PRPF8 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| PITPNA | PMVK, MORF4L2, MLKL, SCP2, CSNK2B, ACP1, CCDC58, GOT1, HADH, HSPB1, NECAP1, VAPA, UBE2L3, PLK1, S1PR4 | PRPF8 | CD2BP2, SNRNP40, SNRPB, RNPS1, MYC, RNU11, EFTUD2, ABCA1, USP39, PRPF4, MEPCE, GIGYF2, SRRM1, ZBTB7B, SNW1, PRPF3, UBC, HDAC5, TOP1, SF3A2, SIRT7, HNRNPA1, TCF3, ERG, CUL3, SART1, SERPINB2, PRPF6, SNRNP200, PRPF8, DHX9, SNRPD3, SNRPE, SNRPD1, SF3B3, SNRPD2, SF3B1, SNRPA1, HNRNPU, U2AF1, SNRNP70, SF3A1, PRPF19, CDC5L, SF3B6, HNRNPM, CRNKL1, DDX3X, PRKDC, PRPF4B, SMU1, AAR2, ECD, RPL37A, TRIM55, SART3, RPL6, VTN, HUWE1, RANGAP1, RPS14, S100A9, SEPT7, RPS25, SUPT16H, SEPT2, NOTCH1, EIF4A3, MAGOH, HSP90AA1, FN1, VCAM1, SF3B2, SF3B4, BCAS2, SLU7, WDR83, ZNF830, PCBP1, HNRNPH2, GPKOW, RBM5, SRPK1, ITGA4, SND1, IGSF8, ICAM1, FBXO6, NEDD4, PIN1, RPA1, RPA2, RPA3, WWOX, ASB15, LGR4, STAU1, CDKN1A, SHMT2, NXF1, PHF6, CUL7, OBSL1, CCDC8, UBE2I, SUZ12, EED, RNF2, SIRT6, GCFC2, DDX23, TSSC4, BSG, ZBTB46, ZMYND11, NTRK1, ABAT, CDC40, G3BP2, ISY1-RAB43, ISY1, KPNA4, LUC7L2, MED13, NACA, PIP4K2A, PIP4K2B, PIP4K2C, PLRG1, DHX15, HNRNPR, MED12, MYBBP1A, NOP2, PABPC1, PRPF31, PSMD14, RALY, RPLP0, SRPK2, SRRM2, TUBA4A, USP9X, RANBP2, RNU12, SCARB2, FOXM1, FOXQ1, MCM5, ESR1, MEX3C, AR, U2AF2, TTC27, C1orf131, C9orf78, ZNF746, SNRPF, SNRPN, KIAA1143, SNRPG, EAPP, GPR156, RIOK1, NCL, ZNHIT2, RUVBL1, RUVBL2, SLC7A6OS, URI1, WDR92, TRIM25, YAP1, MTF1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for PITPNA_PRPF8 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for PITPNA_PRPF8 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | PRPF8 | C1838702 | Retinitis Pigmentosa 13 | 2 | CTD_human;UNIPROT |
| Tgene | PRPF8 | C0019693 | HIV Infections | 1 | CTD_human |
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