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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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Fusion gene ID: 26892

FusionGeneSummary for PHC3_SLC7A14

check button Fusion gene summary
Fusion gene informationFusion gene name: PHC3_SLC7A14
Fusion gene ID: 26892
HgeneTgene
Gene symbol

PHC3

SLC7A14

Gene ID

80012

57709

Gene namepolyhomeotic homolog 3solute carrier family 7 member 14
SynonymsEDR3|HPH3PPP1R142
Cytomap

3q26.2

3q26.2

Type of geneprotein-codingprotein-coding
Descriptionpolyhomeotic-like protein 3early development regulator 3early development regulatory protein 3homolog of polyhomeotic 3polyhomeotic like 3probable cationic amino acid transporterprotein phosphatase 1, regulatory subunit 142solute carrier family 7 (cationic amino acid transporter, y+ system), member 14solute carrier family 7 (orphan transporter), member 14
Modification date2018051920180519
UniProtAcc

Q8NDX5

Q8TBB6

Ensembl transtripts involved in fusion geneENST00000495893, ENST00000494943, 
ENST00000467570, ENST00000474275, 
ENST00000497658, ENST00000481639, 
ENST00000231706, ENST00000466168, 
Fusion gene scores* DoF score10 X 9 X 7=6304 X 3 X 6=72
# samples 127
** MAII scorelog2(12/630*10)=-2.39231742277876
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/72*10)=-0.0406419844973459
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PHC3 [Title/Abstract] AND SLC7A14 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationTumor suppressor gene involved fusion gene, in-frame but not retained their domain.
Tumor suppressor gene involved fusion gene, retained protein feature but frameshift.
DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneSLC7A14

GO:0010923

negative regulation of phosphatase activity

19389623


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVKIRPTCGA-G7-6793-01APHC3chr3

169863211

-SLC7A14chr3

170185165

-
TCGARVLIHCTCGA-2Y-A9H0-01APHC3chr3

169896561

-SLC7A14chr3

170185165

-
TCGARVLUSCTCGA-94-7943-01APHC3chr3

169854207

-SLC7A14chr3

170185165

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000495893ENST00000231706PHC3chr3

169863211

-SLC7A14chr3

170185165

-
5CDS-intronENST00000495893ENST00000466168PHC3chr3

169863211

-SLC7A14chr3

170185165

-
Frame-shiftENST00000494943ENST00000231706PHC3chr3

169863211

-SLC7A14chr3

170185165

-
5CDS-intronENST00000494943ENST00000466168PHC3chr3

169863211

-SLC7A14chr3

170185165

-
Frame-shiftENST00000467570ENST00000231706PHC3chr3

169863211

-SLC7A14chr3

170185165

-
5CDS-intronENST00000467570ENST00000466168PHC3chr3

169863211

-SLC7A14chr3

170185165

-
intron-3CDSENST00000474275ENST00000231706PHC3chr3

169863211

-SLC7A14chr3

170185165

-
intron-intronENST00000474275ENST00000466168PHC3chr3

169863211

-SLC7A14chr3

170185165

-
intron-3CDSENST00000497658ENST00000231706PHC3chr3

169863211

-SLC7A14chr3

170185165

-
intron-intronENST00000497658ENST00000466168PHC3chr3

169863211

-SLC7A14chr3

170185165

-
intron-3CDSENST00000481639ENST00000231706PHC3chr3

169863211

-SLC7A14chr3

170185165

-
intron-intronENST00000481639ENST00000466168PHC3chr3

169863211

-SLC7A14chr3

170185165

-
Frame-shiftENST00000495893ENST00000231706PHC3chr3

169896561

-SLC7A14chr3

170185165

-
5CDS-intronENST00000495893ENST00000466168PHC3chr3

169896561

-SLC7A14chr3

170185165

-
Frame-shiftENST00000494943ENST00000231706PHC3chr3

169896561

-SLC7A14chr3

170185165

-
5CDS-intronENST00000494943ENST00000466168PHC3chr3

169896561

-SLC7A14chr3

170185165

-
Frame-shiftENST00000467570ENST00000231706PHC3chr3

169896561

-SLC7A14chr3

170185165

-
5CDS-intronENST00000467570ENST00000466168PHC3chr3

169896561

-SLC7A14chr3

170185165

-
Frame-shiftENST00000474275ENST00000231706PHC3chr3

169896561

-SLC7A14chr3

170185165

-
5CDS-intronENST00000474275ENST00000466168PHC3chr3

169896561

-SLC7A14chr3

170185165

-
Frame-shiftENST00000497658ENST00000231706PHC3chr3

169896561

-SLC7A14chr3

170185165

-
5CDS-intronENST00000497658ENST00000466168PHC3chr3

169896561

-SLC7A14chr3

170185165

-
Frame-shiftENST00000481639ENST00000231706PHC3chr3

169896561

-SLC7A14chr3

170185165

-
5CDS-intronENST00000481639ENST00000466168PHC3chr3

169896561

-SLC7A14chr3

170185165

-
In-frameENST00000495893ENST00000231706PHC3chr3

169854207

-SLC7A14chr3

170185165

-
5CDS-intronENST00000495893ENST00000466168PHC3chr3

169854207

-SLC7A14chr3

170185165

-
In-frameENST00000494943ENST00000231706PHC3chr3

169854207

-SLC7A14chr3

170185165

-
5CDS-intronENST00000494943ENST00000466168PHC3chr3

169854207

-SLC7A14chr3

170185165

-
In-frameENST00000467570ENST00000231706PHC3chr3

169854207

-SLC7A14chr3

170185165

-
5CDS-intronENST00000467570ENST00000466168PHC3chr3

169854207

-SLC7A14chr3

170185165

-
intron-3CDSENST00000474275ENST00000231706PHC3chr3

169854207

-SLC7A14chr3

170185165

-
intron-intronENST00000474275ENST00000466168PHC3chr3

169854207

-SLC7A14chr3

170185165

-
intron-3CDSENST00000497658ENST00000231706PHC3chr3

169854207

-SLC7A14chr3

170185165

-
intron-intronENST00000497658ENST00000466168PHC3chr3

169854207

-SLC7A14chr3

170185165

-
intron-3CDSENST00000481639ENST00000231706PHC3chr3

169854207

-SLC7A14chr3

170185165

-
intron-intronENST00000481639ENST00000466168PHC3chr3

169854207

-SLC7A14chr3

170185165

-

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FusionProtFeatures for PHC3_SLC7A14


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
PHC3

Q8NDX5

SLC7A14

Q8TBB6

May be involved in arginine transport.{ECO:0000269|PubMed:22787143, ECO:0000269|PubMed:24670872}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePHC3chr3:169854207chr3:170185165ENST00000494943-71519_26294984Compositional biasNote=Poly-Thr
HgenePHC3chr3:169854207chr3:170185165ENST00000494943-71589_287294984Compositional biasNote=Ser-rich
HgenePHC3chr3:169854207chr3:170185165ENST00000495893-71519_26306996Compositional biasNote=Poly-Thr
HgenePHC3chr3:169854207chr3:170185165ENST00000495893-71589_287306996Compositional biasNote=Ser-rich

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePHC3chr3:169854207chr3:170185165ENST00000474275-1519_26-22187Compositional biasNote=Poly-Thr
HgenePHC3chr3:169854207chr3:170185165ENST00000474275-15324_539-22187Compositional biasNote=Gln-rich
HgenePHC3chr3:169854207chr3:170185165ENST00000474275-15346_670-22187Compositional biasNote=Pro-rich
HgenePHC3chr3:169854207chr3:170185165ENST00000474275-1589_287-22187Compositional biasNote=Ser-rich
HgenePHC3chr3:169854207chr3:170185165ENST00000494943-715324_539294984Compositional biasNote=Gln-rich
HgenePHC3chr3:169854207chr3:170185165ENST00000494943-715346_670294984Compositional biasNote=Pro-rich
HgenePHC3chr3:169854207chr3:170185165ENST00000495893-715324_539306996Compositional biasNote=Gln-rich
HgenePHC3chr3:169854207chr3:170185165ENST00000495893-715346_670306996Compositional biasNote=Pro-rich
HgenePHC3chr3:169854207chr3:170185165ENST00000497658-1419_26-6152Compositional biasNote=Poly-Thr
HgenePHC3chr3:169854207chr3:170185165ENST00000497658-14324_539-6152Compositional biasNote=Gln-rich
HgenePHC3chr3:169854207chr3:170185165ENST00000497658-14346_670-6152Compositional biasNote=Pro-rich
HgenePHC3chr3:169854207chr3:170185165ENST00000497658-1489_287-6152Compositional biasNote=Ser-rich
HgenePHC3chr3:169854207chr3:170185165ENST00000474275-15919_983-22187DomainSAM
HgenePHC3chr3:169854207chr3:170185165ENST00000494943-715919_983294984DomainSAM
HgenePHC3chr3:169854207chr3:170185165ENST00000495893-715919_983306996DomainSAM
HgenePHC3chr3:169854207chr3:170185165ENST00000497658-14919_983-6152DomainSAM
HgenePHC3chr3:169854207chr3:170185165ENST00000474275-15691_720-22187MotifNote=HD1
HgenePHC3chr3:169854207chr3:170185165ENST00000494943-715691_720294984MotifNote=HD1
HgenePHC3chr3:169854207chr3:170185165ENST00000495893-715691_720306996MotifNote=HD1
HgenePHC3chr3:169854207chr3:170185165ENST00000497658-14691_720-6152MotifNote=HD1
HgenePHC3chr3:169854207chr3:170185165ENST00000474275-15776_810-22187Zinc fingerFCS-type
HgenePHC3chr3:169854207chr3:170185165ENST00000494943-715776_810294984Zinc fingerFCS-type
HgenePHC3chr3:169854207chr3:170185165ENST00000495893-715776_810306996Zinc fingerFCS-type
HgenePHC3chr3:169854207chr3:170185165ENST00000497658-14776_810-6152Zinc fingerFCS-type
TgeneSLC7A14chr3:169854207chr3:170185165ENST00000231706-68119_141664772TransmembraneHelical
TgeneSLC7A14chr3:169854207chr3:170185165ENST00000231706-68187_207664772TransmembraneHelical
TgeneSLC7A14chr3:169854207chr3:170185165ENST00000231706-68216_236664772TransmembraneHelical
TgeneSLC7A14chr3:169854207chr3:170185165ENST00000231706-68251_271664772TransmembraneHelical
TgeneSLC7A14chr3:169854207chr3:170185165ENST00000231706-68291_311664772TransmembraneHelical
TgeneSLC7A14chr3:169854207chr3:170185165ENST00000231706-68336_356664772TransmembraneHelical
TgeneSLC7A14chr3:169854207chr3:170185165ENST00000231706-68360_380664772TransmembraneHelical
TgeneSLC7A14chr3:169854207chr3:170185165ENST00000231706-68384_404664772TransmembraneHelical
TgeneSLC7A14chr3:169854207chr3:170185165ENST00000231706-68407_427664772TransmembraneHelical
TgeneSLC7A14chr3:169854207chr3:170185165ENST00000231706-68565_585664772TransmembraneHelical
TgeneSLC7A14chr3:169854207chr3:170185165ENST00000231706-6858_78664772TransmembraneHelical
TgeneSLC7A14chr3:169854207chr3:170185165ENST00000231706-68596_616664772TransmembraneHelical
TgeneSLC7A14chr3:169854207chr3:170185165ENST00000231706-68628_648664772TransmembraneHelical
TgeneSLC7A14chr3:169854207chr3:170185165ENST00000231706-68655_675664772TransmembraneHelical
TgeneSLC7A14chr3:169854207chr3:170185165ENST00000231706-6883_103664772TransmembraneHelical


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FusionGeneSequence for PHC3_SLC7A14


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_PHC3_ENST00000495893_chr3_169854207_-_SLC7A14_ENST00000231706_chr3_170185165_-_414aa
MAEAEFKDHSTAMDTEPNPGTSSVSTTTSSTTTTTITTSSSRMQQPQISVYSGSDRHAVQVIQQALHRPPSSAAQYLQQMYAAQQQHLML
HTAALQQQHLSSSQLQSLAAVQASLSSGRPSTSPTGSVTQQSSMSQTSINLSTSPTPAQLISRSQASSSTSGSITQQTMLLGSTSPTLTA
SQAQMYLRAQMLIFTPATTVAAVQSDIPVVSSSSSSSCQSAATQVQNLTLRSQKLGVLSSSQNGPPKSTSQTQSLTICHNKTTVTSSKIS
QRDPSPESNKKGESPSLESRSTAVTRTSSIHQLIAPGLLIYFGYGIWNSTLEISAREEALHQSTYQRYDVDDPFSVEEGFSYATEGESQE

>In-frame_PHC3_ENST00000494943_chr3_169854207_-_SLC7A14_ENST00000231706_chr3_170185165_-_402aa
MDTEPNPGTSSVSTTTSSTTTTTITTSSSRMQQPQISVYSGSDRHAVQVIQQALHRPPSSAAQYLQQMYAAQQQHLMLHTAALQQQHLSS
SQLQSLAAVQASLSSGRPSTSPTGSVTQQSSMSQTSINLSTSPTPAQLISRSQASSSTSGSITQQTMLLGSTSPTLTASQAQMYLRAQML
IFTPATTVAAVQSDIPVVSSSSSSSCQSAATQVQNLTLRSQKLGVLSSSQNGPPKSTSQTQSLTICHNKTTVTSSKISQRDPSPESNKKG
ESPSLESRSTAVTRTSSIHQLIAPGLLIYFGYGIWNSTLEISAREEALHQSTYQRYDVDDPFSVEEGFSYATEGESQEDWGGPTEDKGFY

>In-frame_PHC3_ENST00000467570_chr3_169854207_-_SLC7A14_ENST00000231706_chr3_170185165_-_361aa
MAEAEFKDHSTAMDTEPNPGTSSVSTTTSSTTTTTITTSSSRMQQPQISVYSGSDRHAVQVIQQALHRPPSSAAQYLQQMYAAQQQHLML
HTAALQQQHLSSSQLQSLAAVQASLSSGRPSTSPTGSVTQQSSMSQTSLIFTPATTVAAVQSDIPVVSSSSSSSCQSAATQVQNLTLRSQ
KLGVLSSSQNGPPKSTSQTQSLTICHNKTTVTSSKISQRDPSPESNKKGESPSLESRSTAVTRTSSIHQLIAPGLLIYFGYGIWNSTLEI
SAREEALHQSTYQRYDVDDPFSVEEGFSYATEGESQEDWGGPTEDKGFYYQQMSDAKANGRTSSKAKSKSKHKQNSEALIANDELDYSPE


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_PHC3_ENST00000495893_chr3_169854207_-_SLC7A14_ENST00000231706_chr3_170185165_-_1242nt
ATGGCGGAAGCGGAATTTAAGGACCATAGTACAGCTATGGATACTGAACCAAACCCGGGAACATCTTCTGTGTCAACAACAACCAGCAGT
ACCACCACCACCACCATCACCACTTCCTCCTCTCGAATGCAGCAGCCACAGATCTCTGTCTACAGTGGTTCAGACCGACATGCTGTACAG
GTAATTCAACAGGCATTGCATCGGCCCCCCAGCTCAGCTGCTCAGTACCTTCAGCAAATGTATGCAGCCCAACAACAGCACTTGATGCTG
CATACTGCAGCTCTTCAGCAGCAGCATTTAAGCAGCTCCCAGCTTCAGAGCCTTGCTGCTGTTCAGGCAAGTTTGTCCAGTGGAAGACCA
TCTACATCTCCCACAGGAAGTGTCACACAGCAGTCAAGTATGTCCCAAACGTCTATCAACCTCTCCACTTCTCCTACACCTGCACAGTTA
ATAAGCCGTTCCCAGGCTTCCAGTTCTACCAGCGGCAGTATTACCCAACAGACTATGTTACTAGGGAGTACTTCCCCTACCCTAACGGCA
AGCCAAGCTCAAATGTATCTCCGAGCTCAAATGCTGATTTTCACACCCGCTACCACTGTGGCTGCTGTACAGTCTGACATTCCTGTTGTC
TCGTCGTCATCGTCATCTTCCTGTCAGTCTGCAGCTACTCAGGTTCAGAATTTAACATTACGCAGCCAGAAGTTGGGTGTATTATCTAGC
TCACAGAATGGTCCACCAAAAAGCACTAGTCAAACTCAGTCATTGACAATTTGTCATAACAAAACAACAGTGACCAGTTCTAAAATCAGC
CAACGAGATCCTTCTCCAGAAAGTAATAAGAAAGGAGAGAGCCCAAGCCTGGAATCACGAAGCACAGCTGTCACCCGGACATCAAGTATT
CACCAGTTAATAGCACCAGGTCTGCTCATTTATTTTGGATATGGCATCTGGAACAGCACCCTGGAAATCAGCGCTCGAGAAGAGGCCCTG
CACCAAAGCACGTACCAACGCTACGACGTGGATGACCCCTTCTCAGTGGAGGAGGGTTTCTCCTACGCCACAGAGGGCGAGAGCCAGGAG
GACTGGGGCGGGCCCACTGAAGACAAAGGCTTCTATTACCAACAGATGTCAGATGCGAAGGCAAACGGCCGGACAAGTAGCAAAGCGAAG

>In-frame_PHC3_ENST00000494943_chr3_169854207_-_SLC7A14_ENST00000231706_chr3_170185165_-_1206nt
ATGGATACTGAACCAAACCCGGGAACATCTTCTGTGTCAACAACAACCAGCAGTACCACCACCACCACCATCACCACTTCCTCCTCTCGA
ATGCAGCAGCCACAGATCTCTGTCTACAGTGGTTCAGACCGACATGCTGTACAGGTAATTCAACAGGCATTGCATCGGCCCCCCAGCTCA
GCTGCTCAGTACCTTCAGCAAATGTATGCAGCCCAACAACAGCACTTGATGCTGCATACTGCAGCTCTTCAGCAGCAGCATTTAAGCAGC
TCCCAGCTTCAGAGCCTTGCTGCTGTTCAGGCAAGTTTGTCCAGTGGAAGACCATCTACATCTCCCACAGGAAGTGTCACACAGCAGTCA
AGTATGTCCCAAACGTCTATCAACCTCTCCACTTCTCCTACACCTGCACAGTTAATAAGCCGTTCCCAGGCTTCCAGTTCTACCAGCGGC
AGTATTACCCAACAGACTATGTTACTAGGGAGTACTTCCCCTACCCTAACGGCAAGCCAAGCTCAAATGTATCTCCGAGCTCAAATGCTG
ATTTTCACACCCGCTACCACTGTGGCTGCTGTACAGTCTGACATTCCTGTTGTCTCGTCGTCATCGTCATCTTCCTGTCAGTCTGCAGCT
ACTCAGGTTCAGAATTTAACATTACGCAGCCAGAAGTTGGGTGTATTATCTAGCTCACAGAATGGTCCACCAAAAAGCACTAGTCAAACT
CAGTCATTGACAATTTGTCATAACAAAACAACAGTGACCAGTTCTAAAATCAGCCAACGAGATCCTTCTCCAGAAAGTAATAAGAAAGGA
GAGAGCCCAAGCCTGGAATCACGAAGCACAGCTGTCACCCGGACATCAAGTATTCACCAGTTAATAGCACCAGGTCTGCTCATTTATTTT
GGATATGGCATCTGGAACAGCACCCTGGAAATCAGCGCTCGAGAAGAGGCCCTGCACCAAAGCACGTACCAACGCTACGACGTGGATGAC
CCCTTCTCAGTGGAGGAGGGTTTCTCCTACGCCACAGAGGGCGAGAGCCAGGAGGACTGGGGCGGGCCCACTGAAGACAAAGGCTTCTAT
TACCAACAGATGTCAGATGCGAAGGCAAACGGCCGGACAAGTAGCAAAGCGAAGAGCAAAAGCAAACACAAACAGAACTCAGAGGCCCTG

>In-frame_PHC3_ENST00000467570_chr3_169854207_-_SLC7A14_ENST00000231706_chr3_170185165_-_1083nt
ATGGCGGAAGCGGAATTTAAGGACCATAGTACAGCTATGGATACTGAACCAAACCCGGGAACATCTTCTGTGTCAACAACAACCAGCAGT
ACCACCACCACCACCATCACCACTTCCTCCTCTCGAATGCAGCAGCCACAGATCTCTGTCTACAGTGGTTCAGACCGACATGCTGTACAG
GTAATTCAACAGGCATTGCATCGGCCCCCCAGCTCAGCTGCTCAGTACCTTCAGCAAATGTATGCAGCCCAACAACAGCACTTGATGCTG
CATACTGCAGCTCTTCAGCAGCAGCATTTAAGCAGCTCCCAGCTTCAGAGCCTTGCTGCTGTTCAGGCAAGTTTGTCCAGTGGAAGACCA
TCTACATCTCCCACAGGAAGTGTCACACAGCAGTCAAGTATGTCCCAAACGTCTCTGATTTTCACACCCGCTACCACTGTGGCTGCTGTA
CAGTCTGACATTCCTGTTGTCTCGTCGTCATCGTCATCTTCCTGTCAGTCTGCAGCTACTCAGGTTCAGAATTTAACATTACGCAGCCAG
AAGTTGGGTGTATTATCTAGCTCACAGAATGGTCCACCAAAAAGCACTAGTCAAACTCAGTCATTGACAATTTGTCATAACAAAACAACA
GTGACCAGTTCTAAAATCAGCCAACGAGATCCTTCTCCAGAAAGTAATAAGAAAGGAGAGAGCCCAAGCCTGGAATCACGAAGCACAGCT
GTCACCCGGACATCAAGTATTCACCAGTTAATAGCACCAGGTCTGCTCATTTATTTTGGATATGGCATCTGGAACAGCACCCTGGAAATC
AGCGCTCGAGAAGAGGCCCTGCACCAAAGCACGTACCAACGCTACGACGTGGATGACCCCTTCTCAGTGGAGGAGGGTTTCTCCTACGCC
ACAGAGGGCGAGAGCCAGGAGGACTGGGGCGGGCCCACTGAAGACAAAGGCTTCTATTACCAACAGATGTCAGATGCGAAGGCAAACGGC
CGGACAAGTAGCAAAGCGAAGAGCAAAAGCAAACACAAACAGAACTCAGAGGCCCTGATTGCAAATGATGAGTTAGATTACTCTCCAGAG


* Fusion transcript sequences (Full-length transcript).
>In-frame_PHC3_ENST00000495893_chr3_169854207_-_SLC7A14_ENST00000231706_chr3_170185165_-_8745nt
GCGCAGCCCATGTTAGTGATGGAGGAGAGAAGATGGCGGAAGCGGAATTTAAGGACCATAGTACAGCTATGGATACTGAACCAAACCCGG
GAACATCTTCTGTGTCAACAACAACCAGCAGTACCACCACCACCACCATCACCACTTCCTCCTCTCGAATGCAGCAGCCACAGATCTCTG
TCTACAGTGGTTCAGACCGACATGCTGTACAGGTAATTCAACAGGCATTGCATCGGCCCCCCAGCTCAGCTGCTCAGTACCTTCAGCAAA
TGTATGCAGCCCAACAACAGCACTTGATGCTGCATACTGCAGCTCTTCAGCAGCAGCATTTAAGCAGCTCCCAGCTTCAGAGCCTTGCTG
CTGTTCAGGCAAGTTTGTCCAGTGGAAGACCATCTACATCTCCCACAGGAAGTGTCACACAGCAGTCAAGTATGTCCCAAACGTCTATCA
ACCTCTCCACTTCTCCTACACCTGCACAGTTAATAAGCCGTTCCCAGGCTTCCAGTTCTACCAGCGGCAGTATTACCCAACAGACTATGT
TACTAGGGAGTACTTCCCCTACCCTAACGGCAAGCCAAGCTCAAATGTATCTCCGAGCTCAAATGCTGATTTTCACACCCGCTACCACTG
TGGCTGCTGTACAGTCTGACATTCCTGTTGTCTCGTCGTCATCGTCATCTTCCTGTCAGTCTGCAGCTACTCAGGTTCAGAATTTAACAT
TACGCAGCCAGAAGTTGGGTGTATTATCTAGCTCACAGAATGGTCCACCAAAAAGCACTAGTCAAACTCAGTCATTGACAATTTGTCATA
ACAAAACAACAGTGACCAGTTCTAAAATCAGCCAACGAGATCCTTCTCCAGAAAGTAATAAGAAAGGAGAGAGCCCAAGCCTGGAATCAC
GAAGCACAGCTGTCACCCGGACATCAAGTATTCACCAGTTAATAGCACCAGGTCTGCTCATTTATTTTGGATATGGCATCTGGAACAGCA
CCCTGGAAATCAGCGCTCGAGAAGAGGCCCTGCACCAAAGCACGTACCAACGCTACGACGTGGATGACCCCTTCTCAGTGGAGGAGGGTT
TCTCCTACGCCACAGAGGGCGAGAGCCAGGAGGACTGGGGCGGGCCCACTGAAGACAAAGGCTTCTATTACCAACAGATGTCAGATGCGA
AGGCAAACGGCCGGACAAGTAGCAAAGCGAAGAGCAAAAGCAAACACAAACAGAACTCAGAGGCCCTGATTGCAAATGATGAGTTAGATT
ACTCTCCAGAGTAGGAGAAACACACAAGTGGGTAGAAATGGTGATGACTGATTTTCAGTAACTTAACCTGTGGGCTAGAAGGTGAAAACT
TTTTTGGCTCTCATTTCACAAATCCAGCCTTCCCCAAATTCAATCCCTAGTCATAGCCTGTCATTTGCTACTTTTGCTCTTCAGGATAGT
TCTGTTGAAGGGCTTAACCTGGGTCCCCTAACTGGTCGCCTTGTTAAATAAAATAAATAAATAAACAAGAGGCTATATGAAATTCCATCT
TAGGTGCAACCACCAGAGCTGATGGTACCAAATGTTTCCTAGGCCTTTGCTTTGCTGGTTGAAGCCCAAGCAGGGGCTCTGGGCAGAAGG
CAGAATTTCAGTCACCTGAGACATGGGGACAAAGCTCTGTTCTTGGCATGTCAGGCTGAGTGCTGCTCCCCGAGGTCAGGGTGGGTAGAT
GGGCATTGGCACTTCCTGAGCAAGCATCATTTTATCCTGCAATCTCACCCAAAATTAATTCATGGAAAAGACACATGCTTCTTTTTATTC
ACCAACATTCTCACAGCTTCCAAACTATAATTTTAGGATCCAGCAAAGTTCAGGGACTCTGGACCATTTTCCCAATGGTTTCAGATTCAC
CATAAAGCAGTCAGGCAGACCCAGTGATATGGTAAGAAGCACCATCAAAGCTCTATGTAAATGCCCAGAAGAAAATTAAATAACCATATC
TTGCGGTAAAAGCCAGAAGGGCATTGGCAGAAATTAACTCTCTGTCATGGCCTCTCTTATATCAGACTGCAGCTCCTGGTGATATGATGA
AAGCGGGCAAAGGTGGAGCATGATTTCATGGCACTGATATGCCTTGAAAAAGTAGGTTGTTTGTTTTATAATCAGATAAAAATTTTTACA
AGGAGAAGTGAGCCAGCCACTGAGATCACATTGCAAATTCTCTTTCATATTTCTAAAATTATAAATTCTAAAGTTTTTGAGATAGGCAAC
CACTTGATTGGTGTGTGCTACTCTGAAAACAAAATAGGCTGAAGTATAGCGACTTAGGTAGTTGCATTCCATGAGATCACATTTCACTTC
TGAACCTTATTCCTTGGGGCTAGCTCACTTTCAGAGGTGTATTTTTTTTTCCTGTTATTTCCCAGAGTAGTTTCACTGAAGCCCAGAGAA
ATATCTACCTGGTAAGATGTAAATTTGGGCCATAAAAGGGGCTATTAAAAGAATTTTCTCAGAAATAGAATAGATGAGAGAATTTGCAAA
GGAAAAAAACACACATGGGCTACAATATAAATTCTACTCTTGGGTTACAAGAATTCCTGTGGCTGCACTGAGATACGTACAAATGTATGT
GAAGGCACAATTTGAATCAAGCTATCATAGAATTAACCAAGCTATTAAAATTAATCAAGCTATTAATAAAATCTCTGTGAGGATTTCCTG
AAAGAGGGACAAAAGAAGAAATTCCTTGTCCTTTCTCTCCTGGATGTATCAGTATGCCAAACGTTTTCCAGAACATATTCGCTAGCACTC
AAGTCTGTTCTTTCTGAAAGGCTGAGGCTCATGCCATCTTGGCATGCTTTAGGATTATGGCAAGGAGGTAAAAGTCCATTTTTTCATTCA
ACTAACACTGGTTGAGAATAGACCCAATGCTAAGTGACAGGAATGAATAGAAGCATGGCACTTGCCCTTGGGGGCTACAGTCCATGGATG
AGCAGCACTGGAGCCTGGTAAATGCAGATAAAACAACAAACTTGACAAGTCTCCAGGCTGATGCACTGGGTTTTAACATACATATAAAGA
TGAATTGAAACTAGTTTTTAAAAAATATGCTTTAAATAAATTACATATCGTAATCATAGCCAATGTATACCATTAAACTAAAATAACTGC
AATTTTCTAGATATTTTTTATTCTTCTGTAGTCATTGTTTAGAACTCTGGTTTCCTGAGGTCATTTTGTCATTTTAATATCATGCTTGAC
AATGCTATGTTTTCTCTTCCCTAGAGTTAACCATAAAGATACAGTGCCTACTCTGTGAAATACAGCATTAGGAATTAATTATAAACTAAT
TATCAGTCATCTTTTGAAAACAAAGTTTTGAATTGGCTATAGGACTCAACAAATCTGCCTGGTGTAAATAGAATCTGTTAAGCTTGATAC
ATATCTAGATAGATGAGGAGGGGTTGTATTCATTAAGCATGAGAATAGAGAAATAGGAGTGCAAAATGGCAAAATCTTAACGTGGGTGAA
AGAGCTTCCTTTTACTAGTGAGGTTTAAGTATTAAAGTAACAATAGCCTGGTGGCAGATGAATGCAATTTCTATAGGATGGGAATGGAAA
ATGTATGCTTTGGTTAACACCATTGCTGTTGACTTCATGCAGATTCTATTAAGCACTCTCATTTCAGGAGCCATTTTTCCCACATAGTAT
ATTAGTATATTTTAAGCTTAGCTCCCTTTATTTTTCTAAAGTTGATAAATCACCTCCCTAGCAACCTTAGTTTTAAAAAAAAAATCACTA
AGATAGAAAAAGTATTTTCAGGTACATAGACATGTTTGTCCTCAGGTTTACCTGCTTCTGTGAACAGTCCCAGATTTTACAATGCAGTTT
TCAAATACCATCAATCACTACAATGACAATATTACTATTTTCTTAACAGGTTTCTAAACGATGTATGTGTGGGATCACATTAAAAGTAAG
ATCACCTTATAATTATCTTAGAAACTTTGCCCCTTGAAGGGAGTCCAAGGAAGACCTACATTTTATTGAATTCTGAATAGCAAAAGCTCT
CCGAGTGAGATTTCATTGTGTGGATTTGTGGTTTGGAGCCAATTACTTGATTTTCTTCAGATTTTATTCTACTTATTTATTGGTACTCTG
CTTCATTTCAAAAGGATTTGAGGCAGCTACTAAAATATATATAATACAAAACAAAAATTAAGTGAGGAACTCAGAGCAAACAAAAATAGA
AACAGAAAGGATAAGACAAAACTAGACGTATATTTAGTACATAAATGCAGAACCCTGACATGCTTTACTAAATTTGCCAATGAGTGACAC
CATGAAAAATAATAGAATTAGTGGTAATGACAAGAAGAAGTACTTCTGCATGATAAGAACAAATCTTTCCCCATGCAGGTAGAGGTTTGA
AATAGCATAGATCATTAAAATCCACAGGTAAGCTTCAAACCTAGATTTTGCTAGCTACATGTGCCTGGCATATAGTGTGTATTCAAGAAA
TACCTGATGATTGACAGAATGAATGAATTGGAGGAAAATGAAATATTTATTCAACAATTACTTGTGGAGTGCCTATTATGTACTATGGCA
GATATTGATATCGTAAGTCAGATAAAAATCCAGCTCTTAAGAAGTAGAGGAAATAGAGCTTGGTGTGGTGGCATGTGCCTATGATCCCAG
ATAGTTGAGAGACTGAGGGAGGAGGATCACTTGAGCCCAGGAGTTCAAGGCTGCAGTGAGCTATGATCACACCACTGTACTCCAGCCTGG
GTAACAGAAGAATACCCTGTCTCTTAAAAAGGAAAATCAAATAGGGGAAATGGGATATATAAATAAAGAACAATAGTGAATGTGTCAGGT
GAGATGACGGACTTGTAATGTGCTGTGGGGGGTCAAATATGAAGAAGGCCTTCTTCCTCTGGAAAGGTCATAAAGAATGTCACACTTGTG
TTGGAACTTGTGAAGTGGGTAGAATTTTATCAAGTAGAAATGAGAGAAAGGCATGCCAAGCAAAGGATCGGCATGAATAAGGTCTACTAG
TTTGTGGTCCTCTGGCTAAGAATTTGTGCTGTGCCTCCATTAAGAGAAAGCAAGGAGCTAGTTTGCCTGGAGCACATGATTTATGCATGA
CTTATACATGCAACAATAAGAAATAATGCTAGGAAGGCAGGTGAGGGATCACTCACAGAGAGACTTGAATGTCACACTGAGCTGACTGGC
TTTCCTCGGGTGAGAGAGTGGGAAATAATTGGGGAACTGACGAAAGTGTGAATCCAGGAAGGCTGAACTTTAAGAAAGCTGAGACGGTGG
CTTCCTTACCTATGCAAGGAACTAACAAGCCACATATACACTCCAAATTGATTTAACAAATTAAAGAGAAAAATAGCTGTACTTTGAGTC
CTGTGTCTGCATTCATCATTAACCTAAGAAAATACAGCCATTTAATACGTGGACAAGCAACACAATTTAACAGCCACTTTAAAGTTTTCA
ACAATAGGTTTCAACAACTAAACCTAACAACTTTTTATATCTATCTAATCTAAACAGTAAAATCTCAGCTCCAGGTTTTACTGAGCTTGA
GTGCTACTTTTTTTTTTTTAGACAGAGTCTCATTCTGTCACCCAGGCTGGAGTGCAGTGGCATGATCTTGGCTCACTGCAACCTTCACCT
CCCGGGTTCAAGCTATTCTCCTGCCTCAGCCTCCCAAGCAGCTGGGATTATAGGCGTGTGCCAGTTCTACTTCTTAGTAACAAACTAGTA
GCTAATCAAATGCCTACATAATGGTCATGATAAATCTGTTTAAATAAATGGCGGGCGGAAGGGAGTTGTTGAATTTAACAATCCATCCTT
CTTCAGAATCTATAGGTCAGCCAGAATATAAATCTAGTAATTATTGAAAAACAAAACACAAACTCCTTCAAAGAAATCTCTCTCCTCTAT
TCTGCTGAAAAGGGTTGGTAAACCTGACATCCTTTCTTTTATTGGAAGACAAATCCAACATTTGTTAGACATCCAACATTTGTTGGAAGT
CTACCTTACAAGAAACCACCTCTTATCTGCAACATAAACAGAAGCTACATCAGGTTGAAAATCCACATAGAAGACTGGAGAAAATTGCCG
TCCCCTTTCGCACTAGGTTTTACCAGGGGCCCAAGATGTCAGAGGAAAGTCCGCGGAGGGCCAAACACAGGTTTACCTAATTATGAATCT
CAGATTAGAATGTCTTATTGTGTGGAAAAGTCAGAACTCAGGAAATGTGTCTGAAGCCAGAGCGGGGGTCTGCTTACGGAGTCTACGCAG
CGGGTAGGGGTCCACTATTGGAGTATAAACCTCAGGTCAGTGAGTAGTGCAGAGGTGTCCCTAACTTCCAATGGAGGGAAAGAGAGGAGA
GCAAAGGAAACACATCCAGAAGTCGCCACGAGGGCTGTGTGCCAGCGCTCCATTTTCATGCTGTTTGGAACAAGACGTGTCAAGGAAGAT
GTTTCTATCCAAAGTCTTCATGGAGCCTCTGCTTCCCCTGTACCTGTGTAGCTCCCTGAAACTGAGGACCCACGTGTCTGCAAAGACCTC
TGGAGATCCTAAGAGAGAGAGGCACCAGCAGGTAACCAGTGGTGGCCTGGCCACGAAAGAGTATTTGAAATTCAACAGTGAGCAAGTGCA
GAAACAGCATCCCAAACCGCAGGCCCCACCACACGCAGGAACCAGAAAGCTGAAGTTTCACCAAGGAGTTTACTTAGTATTTCTCGCTGG
GAATGGGGATGGGTAGCAAAAAGCCCCTTTCATGTACATAATGGTTGGTCCTATGTCCTACTTTTATTTTCTCTAAGAGTTTTAGAAGAA
AGGCTGTTTTAATTTTTTTTTCTCCTTAAGAGCAACTTCCTTTTTAAAATGCTTTCCTCTTCTTGTCCTGCTTGAGTAATGCAGGCATCA
TTCTGAAATCATTCTGAAACAGCTAGGCAGTCGCCTTTTGCCAAAATTACTTCTCTAAGAAAATAGAGTGTTCTTTTTTTTAGGACTTAG
AACCCACAAGGGGTGAGTGGAAGTTTTGTAGCCCATCAAAGGTGAATATGTGTTCTGCAGTATCAACTAAAACAGTGTACAAAATCATTA
AACTGGGCCGGGCGCAGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGTGGATCACCTGAGGCCAGGAGTTCAAGAC
CAGCCTGACCAACATGGAGAAACCCCATCTCTACTAAAAATACAAAATTAGCCAGGTGTGGTGTTGCATGCCTGTAATCCCAGCTATTAG
GGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGGAGGCAGAGGTTGCAGTGAGTCGAGATCACACCATTGCACTCCAGCCTGGGCAATAA
GAGCAAAACTCCGTCTCAAAAATAATAATAATAATAATTTAACTGTGTTCTGCACACACAGAATTACAAAATCCCTATAGGACTTTCACA
GATAGCTTTGGGCTTAAGGTCTTCGGACAACAGGTAGTTCTAATTTCTTACTCTTTGGGACATTTAGTACATGTTGGTACACATAAGGAA
AGAAAATGGCTTATATTAGAGCTAGGAAACAGGGGCAGCCTGGATTTTTATGGTAGGAACTCACTCTGTGCTTTTTTTTTTTTCTGTTAA
GTTTTCTTGACACTGACTTCGGTAACATTGGCTAAAGGGAATTGTGAGTCATGTGAATTTCACCTGCAGTGCAGACTTTAAAGGACTGTG
TTCATTCTGATTTGGGGATGAAGAGAATGTTCCATGCACATCTATTGATTGGTCTTGGCAGTTGCTGATACGCTTGTCTCATTCACACTC
CCAAAGGCGAGGATTTACCCTAGAAATCATAAACCCCCACTTTCCAAAGCAAAGATGCTGTTAATGTTATGATGGTGCATAAATACCTCA
ACTGTCTGGGCTGAGAGAGGGGGCTGCAGGTTTTTAAGAGAGCAGCTATAGTCCTCATTCCATGTAGTCACATCATCTGATGACAGGACT
CCACATTCTAGCTTTTCTCACTGTGGAAAAGAAACGTTACTGTTTAATTAATATCCAAAGTTATAAATACAGCTTGTAAATTTTACTAAC
TTGTTTCTTTTTCGTTTCGTCCTTGAGAAGTACAACTTGCATTTACAGATGGTAATTCCTAGTGTTGTTCTCTGCTATCTTTTTTTGGTA
TGAAATTGCTGTATTTGTTAAAGTTTGTTCGTTTTGTGGTTTTTAATTCCCATTGGTGTGCTGTACAATGTAGTGTATCATGAAGAAAGA
AATAATATGCAGATGTATTATGAAATGTGTTTTATTTTCAAATGTGTGGTGTTGACAATATATTGATTTATCAAGATACTAAGGGAAAAT
TCTAAATTTAACAAAATGTGTATATTTTAATAAATGCATAAAGCTTTATTGTGTGCCTTTAAATTTAAAAATGGGTTTATAAAGAAAGTC
AGAAACAAAAGTGTCTTACTATAAAATATCCATAGTAATGTAAAGCTTTTACACGAGACTACCAAAAAAAAAGAAAGAAAAGAAAAAGGA
GCCTTCCCATATTTTGTTAACCTTAACCAGTATCTGAAGTCTGTTACTTTTTTTCCATTCTTAAATGGAGATGAATAAGTGAATTTCGCC
TTAAGTGTTTCAATTGTCCTTTGTAGAAAAGCCAGATAAATGAGTTCACTTTGAATTGCATTATTGTGGAAAATTCATTTTCAGAATAAA

>In-frame_PHC3_ENST00000494943_chr3_169854207_-_SLC7A14_ENST00000231706_chr3_170185165_-_8746nt
AGTGATGGAGGAGAGAAGATGGCGGAAGCGGAGTGAGTGACTAGATGATTTAAGGACCATAGTACAGCTATGGATACTGAACCAAACCCG
GGAACATCTTCTGTGTCAACAACAACCAGCAGTACCACCACCACCACCATCACCACTTCCTCCTCTCGAATGCAGCAGCCACAGATCTCT
GTCTACAGTGGTTCAGACCGACATGCTGTACAGGTAATTCAACAGGCATTGCATCGGCCCCCCAGCTCAGCTGCTCAGTACCTTCAGCAA
ATGTATGCAGCCCAACAACAGCACTTGATGCTGCATACTGCAGCTCTTCAGCAGCAGCATTTAAGCAGCTCCCAGCTTCAGAGCCTTGCT
GCTGTTCAGGCAAGTTTGTCCAGTGGAAGACCATCTACATCTCCCACAGGAAGTGTCACACAGCAGTCAAGTATGTCCCAAACGTCTATC
AACCTCTCCACTTCTCCTACACCTGCACAGTTAATAAGCCGTTCCCAGGCTTCCAGTTCTACCAGCGGCAGTATTACCCAACAGACTATG
TTACTAGGGAGTACTTCCCCTACCCTAACGGCAAGCCAAGCTCAAATGTATCTCCGAGCTCAAATGCTGATTTTCACACCCGCTACCACT
GTGGCTGCTGTACAGTCTGACATTCCTGTTGTCTCGTCGTCATCGTCATCTTCCTGTCAGTCTGCAGCTACTCAGGTTCAGAATTTAACA
TTACGCAGCCAGAAGTTGGGTGTATTATCTAGCTCACAGAATGGTCCACCAAAAAGCACTAGTCAAACTCAGTCATTGACAATTTGTCAT
AACAAAACAACAGTGACCAGTTCTAAAATCAGCCAACGAGATCCTTCTCCAGAAAGTAATAAGAAAGGAGAGAGCCCAAGCCTGGAATCA
CGAAGCACAGCTGTCACCCGGACATCAAGTATTCACCAGTTAATAGCACCAGGTCTGCTCATTTATTTTGGATATGGCATCTGGAACAGC
ACCCTGGAAATCAGCGCTCGAGAAGAGGCCCTGCACCAAAGCACGTACCAACGCTACGACGTGGATGACCCCTTCTCAGTGGAGGAGGGT
TTCTCCTACGCCACAGAGGGCGAGAGCCAGGAGGACTGGGGCGGGCCCACTGAAGACAAAGGCTTCTATTACCAACAGATGTCAGATGCG
AAGGCAAACGGCCGGACAAGTAGCAAAGCGAAGAGCAAAAGCAAACACAAACAGAACTCAGAGGCCCTGATTGCAAATGATGAGTTAGAT
TACTCTCCAGAGTAGGAGAAACACACAAGTGGGTAGAAATGGTGATGACTGATTTTCAGTAACTTAACCTGTGGGCTAGAAGGTGAAAAC
TTTTTTGGCTCTCATTTCACAAATCCAGCCTTCCCCAAATTCAATCCCTAGTCATAGCCTGTCATTTGCTACTTTTGCTCTTCAGGATAG
TTCTGTTGAAGGGCTTAACCTGGGTCCCCTAACTGGTCGCCTTGTTAAATAAAATAAATAAATAAACAAGAGGCTATATGAAATTCCATC
TTAGGTGCAACCACCAGAGCTGATGGTACCAAATGTTTCCTAGGCCTTTGCTTTGCTGGTTGAAGCCCAAGCAGGGGCTCTGGGCAGAAG
GCAGAATTTCAGTCACCTGAGACATGGGGACAAAGCTCTGTTCTTGGCATGTCAGGCTGAGTGCTGCTCCCCGAGGTCAGGGTGGGTAGA
TGGGCATTGGCACTTCCTGAGCAAGCATCATTTTATCCTGCAATCTCACCCAAAATTAATTCATGGAAAAGACACATGCTTCTTTTTATT
CACCAACATTCTCACAGCTTCCAAACTATAATTTTAGGATCCAGCAAAGTTCAGGGACTCTGGACCATTTTCCCAATGGTTTCAGATTCA
CCATAAAGCAGTCAGGCAGACCCAGTGATATGGTAAGAAGCACCATCAAAGCTCTATGTAAATGCCCAGAAGAAAATTAAATAACCATAT
CTTGCGGTAAAAGCCAGAAGGGCATTGGCAGAAATTAACTCTCTGTCATGGCCTCTCTTATATCAGACTGCAGCTCCTGGTGATATGATG
AAAGCGGGCAAAGGTGGAGCATGATTTCATGGCACTGATATGCCTTGAAAAAGTAGGTTGTTTGTTTTATAATCAGATAAAAATTTTTAC
AAGGAGAAGTGAGCCAGCCACTGAGATCACATTGCAAATTCTCTTTCATATTTCTAAAATTATAAATTCTAAAGTTTTTGAGATAGGCAA
CCACTTGATTGGTGTGTGCTACTCTGAAAACAAAATAGGCTGAAGTATAGCGACTTAGGTAGTTGCATTCCATGAGATCACATTTCACTT
CTGAACCTTATTCCTTGGGGCTAGCTCACTTTCAGAGGTGTATTTTTTTTTCCTGTTATTTCCCAGAGTAGTTTCACTGAAGCCCAGAGA
AATATCTACCTGGTAAGATGTAAATTTGGGCCATAAAAGGGGCTATTAAAAGAATTTTCTCAGAAATAGAATAGATGAGAGAATTTGCAA
AGGAAAAAAACACACATGGGCTACAATATAAATTCTACTCTTGGGTTACAAGAATTCCTGTGGCTGCACTGAGATACGTACAAATGTATG
TGAAGGCACAATTTGAATCAAGCTATCATAGAATTAACCAAGCTATTAAAATTAATCAAGCTATTAATAAAATCTCTGTGAGGATTTCCT
GAAAGAGGGACAAAAGAAGAAATTCCTTGTCCTTTCTCTCCTGGATGTATCAGTATGCCAAACGTTTTCCAGAACATATTCGCTAGCACT
CAAGTCTGTTCTTTCTGAAAGGCTGAGGCTCATGCCATCTTGGCATGCTTTAGGATTATGGCAAGGAGGTAAAAGTCCATTTTTTCATTC
AACTAACACTGGTTGAGAATAGACCCAATGCTAAGTGACAGGAATGAATAGAAGCATGGCACTTGCCCTTGGGGGCTACAGTCCATGGAT
GAGCAGCACTGGAGCCTGGTAAATGCAGATAAAACAACAAACTTGACAAGTCTCCAGGCTGATGCACTGGGTTTTAACATACATATAAAG
ATGAATTGAAACTAGTTTTTAAAAAATATGCTTTAAATAAATTACATATCGTAATCATAGCCAATGTATACCATTAAACTAAAATAACTG
CAATTTTCTAGATATTTTTTATTCTTCTGTAGTCATTGTTTAGAACTCTGGTTTCCTGAGGTCATTTTGTCATTTTAATATCATGCTTGA
CAATGCTATGTTTTCTCTTCCCTAGAGTTAACCATAAAGATACAGTGCCTACTCTGTGAAATACAGCATTAGGAATTAATTATAAACTAA
TTATCAGTCATCTTTTGAAAACAAAGTTTTGAATTGGCTATAGGACTCAACAAATCTGCCTGGTGTAAATAGAATCTGTTAAGCTTGATA
CATATCTAGATAGATGAGGAGGGGTTGTATTCATTAAGCATGAGAATAGAGAAATAGGAGTGCAAAATGGCAAAATCTTAACGTGGGTGA
AAGAGCTTCCTTTTACTAGTGAGGTTTAAGTATTAAAGTAACAATAGCCTGGTGGCAGATGAATGCAATTTCTATAGGATGGGAATGGAA
AATGTATGCTTTGGTTAACACCATTGCTGTTGACTTCATGCAGATTCTATTAAGCACTCTCATTTCAGGAGCCATTTTTCCCACATAGTA
TATTAGTATATTTTAAGCTTAGCTCCCTTTATTTTTCTAAAGTTGATAAATCACCTCCCTAGCAACCTTAGTTTTAAAAAAAAAATCACT
AAGATAGAAAAAGTATTTTCAGGTACATAGACATGTTTGTCCTCAGGTTTACCTGCTTCTGTGAACAGTCCCAGATTTTACAATGCAGTT
TTCAAATACCATCAATCACTACAATGACAATATTACTATTTTCTTAACAGGTTTCTAAACGATGTATGTGTGGGATCACATTAAAAGTAA
GATCACCTTATAATTATCTTAGAAACTTTGCCCCTTGAAGGGAGTCCAAGGAAGACCTACATTTTATTGAATTCTGAATAGCAAAAGCTC
TCCGAGTGAGATTTCATTGTGTGGATTTGTGGTTTGGAGCCAATTACTTGATTTTCTTCAGATTTTATTCTACTTATTTATTGGTACTCT
GCTTCATTTCAAAAGGATTTGAGGCAGCTACTAAAATATATATAATACAAAACAAAAATTAAGTGAGGAACTCAGAGCAAACAAAAATAG
AAACAGAAAGGATAAGACAAAACTAGACGTATATTTAGTACATAAATGCAGAACCCTGACATGCTTTACTAAATTTGCCAATGAGTGACA
CCATGAAAAATAATAGAATTAGTGGTAATGACAAGAAGAAGTACTTCTGCATGATAAGAACAAATCTTTCCCCATGCAGGTAGAGGTTTG
AAATAGCATAGATCATTAAAATCCACAGGTAAGCTTCAAACCTAGATTTTGCTAGCTACATGTGCCTGGCATATAGTGTGTATTCAAGAA
ATACCTGATGATTGACAGAATGAATGAATTGGAGGAAAATGAAATATTTATTCAACAATTACTTGTGGAGTGCCTATTATGTACTATGGC
AGATATTGATATCGTAAGTCAGATAAAAATCCAGCTCTTAAGAAGTAGAGGAAATAGAGCTTGGTGTGGTGGCATGTGCCTATGATCCCA
GATAGTTGAGAGACTGAGGGAGGAGGATCACTTGAGCCCAGGAGTTCAAGGCTGCAGTGAGCTATGATCACACCACTGTACTCCAGCCTG
GGTAACAGAAGAATACCCTGTCTCTTAAAAAGGAAAATCAAATAGGGGAAATGGGATATATAAATAAAGAACAATAGTGAATGTGTCAGG
TGAGATGACGGACTTGTAATGTGCTGTGGGGGGTCAAATATGAAGAAGGCCTTCTTCCTCTGGAAAGGTCATAAAGAATGTCACACTTGT
GTTGGAACTTGTGAAGTGGGTAGAATTTTATCAAGTAGAAATGAGAGAAAGGCATGCCAAGCAAAGGATCGGCATGAATAAGGTCTACTA
GTTTGTGGTCCTCTGGCTAAGAATTTGTGCTGTGCCTCCATTAAGAGAAAGCAAGGAGCTAGTTTGCCTGGAGCACATGATTTATGCATG
ACTTATACATGCAACAATAAGAAATAATGCTAGGAAGGCAGGTGAGGGATCACTCACAGAGAGACTTGAATGTCACACTGAGCTGACTGG
CTTTCCTCGGGTGAGAGAGTGGGAAATAATTGGGGAACTGACGAAAGTGTGAATCCAGGAAGGCTGAACTTTAAGAAAGCTGAGACGGTG
GCTTCCTTACCTATGCAAGGAACTAACAAGCCACATATACACTCCAAATTGATTTAACAAATTAAAGAGAAAAATAGCTGTACTTTGAGT
CCTGTGTCTGCATTCATCATTAACCTAAGAAAATACAGCCATTTAATACGTGGACAAGCAACACAATTTAACAGCCACTTTAAAGTTTTC
AACAATAGGTTTCAACAACTAAACCTAACAACTTTTTATATCTATCTAATCTAAACAGTAAAATCTCAGCTCCAGGTTTTACTGAGCTTG
AGTGCTACTTTTTTTTTTTTAGACAGAGTCTCATTCTGTCACCCAGGCTGGAGTGCAGTGGCATGATCTTGGCTCACTGCAACCTTCACC
TCCCGGGTTCAAGCTATTCTCCTGCCTCAGCCTCCCAAGCAGCTGGGATTATAGGCGTGTGCCAGTTCTACTTCTTAGTAACAAACTAGT
AGCTAATCAAATGCCTACATAATGGTCATGATAAATCTGTTTAAATAAATGGCGGGCGGAAGGGAGTTGTTGAATTTAACAATCCATCCT
TCTTCAGAATCTATAGGTCAGCCAGAATATAAATCTAGTAATTATTGAAAAACAAAACACAAACTCCTTCAAAGAAATCTCTCTCCTCTA
TTCTGCTGAAAAGGGTTGGTAAACCTGACATCCTTTCTTTTATTGGAAGACAAATCCAACATTTGTTAGACATCCAACATTTGTTGGAAG
TCTACCTTACAAGAAACCACCTCTTATCTGCAACATAAACAGAAGCTACATCAGGTTGAAAATCCACATAGAAGACTGGAGAAAATTGCC
GTCCCCTTTCGCACTAGGTTTTACCAGGGGCCCAAGATGTCAGAGGAAAGTCCGCGGAGGGCCAAACACAGGTTTACCTAATTATGAATC
TCAGATTAGAATGTCTTATTGTGTGGAAAAGTCAGAACTCAGGAAATGTGTCTGAAGCCAGAGCGGGGGTCTGCTTACGGAGTCTACGCA
GCGGGTAGGGGTCCACTATTGGAGTATAAACCTCAGGTCAGTGAGTAGTGCAGAGGTGTCCCTAACTTCCAATGGAGGGAAAGAGAGGAG
AGCAAAGGAAACACATCCAGAAGTCGCCACGAGGGCTGTGTGCCAGCGCTCCATTTTCATGCTGTTTGGAACAAGACGTGTCAAGGAAGA
TGTTTCTATCCAAAGTCTTCATGGAGCCTCTGCTTCCCCTGTACCTGTGTAGCTCCCTGAAACTGAGGACCCACGTGTCTGCAAAGACCT
CTGGAGATCCTAAGAGAGAGAGGCACCAGCAGGTAACCAGTGGTGGCCTGGCCACGAAAGAGTATTTGAAATTCAACAGTGAGCAAGTGC
AGAAACAGCATCCCAAACCGCAGGCCCCACCACACGCAGGAACCAGAAAGCTGAAGTTTCACCAAGGAGTTTACTTAGTATTTCTCGCTG
GGAATGGGGATGGGTAGCAAAAAGCCCCTTTCATGTACATAATGGTTGGTCCTATGTCCTACTTTTATTTTCTCTAAGAGTTTTAGAAGA
AAGGCTGTTTTAATTTTTTTTTCTCCTTAAGAGCAACTTCCTTTTTAAAATGCTTTCCTCTTCTTGTCCTGCTTGAGTAATGCAGGCATC
ATTCTGAAATCATTCTGAAACAGCTAGGCAGTCGCCTTTTGCCAAAATTACTTCTCTAAGAAAATAGAGTGTTCTTTTTTTTAGGACTTA
GAACCCACAAGGGGTGAGTGGAAGTTTTGTAGCCCATCAAAGGTGAATATGTGTTCTGCAGTATCAACTAAAACAGTGTACAAAATCATT
AAACTGGGCCGGGCGCAGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGTGGATCACCTGAGGCCAGGAGTTCAAGA
CCAGCCTGACCAACATGGAGAAACCCCATCTCTACTAAAAATACAAAATTAGCCAGGTGTGGTGTTGCATGCCTGTAATCCCAGCTATTA
GGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGGAGGCAGAGGTTGCAGTGAGTCGAGATCACACCATTGCACTCCAGCCTGGGCAATA
AGAGCAAAACTCCGTCTCAAAAATAATAATAATAATAATTTAACTGTGTTCTGCACACACAGAATTACAAAATCCCTATAGGACTTTCAC
AGATAGCTTTGGGCTTAAGGTCTTCGGACAACAGGTAGTTCTAATTTCTTACTCTTTGGGACATTTAGTACATGTTGGTACACATAAGGA
AAGAAAATGGCTTATATTAGAGCTAGGAAACAGGGGCAGCCTGGATTTTTATGGTAGGAACTCACTCTGTGCTTTTTTTTTTTTCTGTTA
AGTTTTCTTGACACTGACTTCGGTAACATTGGCTAAAGGGAATTGTGAGTCATGTGAATTTCACCTGCAGTGCAGACTTTAAAGGACTGT
GTTCATTCTGATTTGGGGATGAAGAGAATGTTCCATGCACATCTATTGATTGGTCTTGGCAGTTGCTGATACGCTTGTCTCATTCACACT
CCCAAAGGCGAGGATTTACCCTAGAAATCATAAACCCCCACTTTCCAAAGCAAAGATGCTGTTAATGTTATGATGGTGCATAAATACCTC
AACTGTCTGGGCTGAGAGAGGGGGCTGCAGGTTTTTAAGAGAGCAGCTATAGTCCTCATTCCATGTAGTCACATCATCTGATGACAGGAC
TCCACATTCTAGCTTTTCTCACTGTGGAAAAGAAACGTTACTGTTTAATTAATATCCAAAGTTATAAATACAGCTTGTAAATTTTACTAA
CTTGTTTCTTTTTCGTTTCGTCCTTGAGAAGTACAACTTGCATTTACAGATGGTAATTCCTAGTGTTGTTCTCTGCTATCTTTTTTTGGT
ATGAAATTGCTGTATTTGTTAAAGTTTGTTCGTTTTGTGGTTTTTAATTCCCATTGGTGTGCTGTACAATGTAGTGTATCATGAAGAAAG
AAATAATATGCAGATGTATTATGAAATGTGTTTTATTTTCAAATGTGTGGTGTTGACAATATATTGATTTATCAAGATACTAAGGGAAAA
TTCTAAATTTAACAAAATGTGTATATTTTAATAAATGCATAAAGCTTTATTGTGTGCCTTTAAATTTAAAAATGGGTTTATAAAGAAAGT
CAGAAACAAAAGTGTCTTACTATAAAATATCCATAGTAATGTAAAGCTTTTACACGAGACTACCAAAAAAAAAGAAAGAAAAGAAAAAGG
AGCCTTCCCATATTTTGTTAACCTTAACCAGTATCTGAAGTCTGTTACTTTTTTTCCATTCTTAAATGGAGATGAATAAGTGAATTTCGC
CTTAAGTGTTTCAATTGTCCTTTGTAGAAAAGCCAGATAAATGAGTTCACTTTGAATTGCATTATTGTGGAAAATTCATTTTCAGAATAA

>In-frame_PHC3_ENST00000467570_chr3_169854207_-_SLC7A14_ENST00000231706_chr3_170185165_-_8588nt
ATGCGCAGCCCATGTTAGTGATGGAGGAGAGAAGATGGCGGAAGCGGAATTTAAGGACCATAGTACAGCTATGGATACTGAACCAAACCC
GGGAACATCTTCTGTGTCAACAACAACCAGCAGTACCACCACCACCACCATCACCACTTCCTCCTCTCGAATGCAGCAGCCACAGATCTC
TGTCTACAGTGGTTCAGACCGACATGCTGTACAGGTAATTCAACAGGCATTGCATCGGCCCCCCAGCTCAGCTGCTCAGTACCTTCAGCA
AATGTATGCAGCCCAACAACAGCACTTGATGCTGCATACTGCAGCTCTTCAGCAGCAGCATTTAAGCAGCTCCCAGCTTCAGAGCCTTGC
TGCTGTTCAGGCAAGTTTGTCCAGTGGAAGACCATCTACATCTCCCACAGGAAGTGTCACACAGCAGTCAAGTATGTCCCAAACGTCTCT
GATTTTCACACCCGCTACCACTGTGGCTGCTGTACAGTCTGACATTCCTGTTGTCTCGTCGTCATCGTCATCTTCCTGTCAGTCTGCAGC
TACTCAGGTTCAGAATTTAACATTACGCAGCCAGAAGTTGGGTGTATTATCTAGCTCACAGAATGGTCCACCAAAAAGCACTAGTCAAAC
TCAGTCATTGACAATTTGTCATAACAAAACAACAGTGACCAGTTCTAAAATCAGCCAACGAGATCCTTCTCCAGAAAGTAATAAGAAAGG
AGAGAGCCCAAGCCTGGAATCACGAAGCACAGCTGTCACCCGGACATCAAGTATTCACCAGTTAATAGCACCAGGTCTGCTCATTTATTT
TGGATATGGCATCTGGAACAGCACCCTGGAAATCAGCGCTCGAGAAGAGGCCCTGCACCAAAGCACGTACCAACGCTACGACGTGGATGA
CCCCTTCTCAGTGGAGGAGGGTTTCTCCTACGCCACAGAGGGCGAGAGCCAGGAGGACTGGGGCGGGCCCACTGAAGACAAAGGCTTCTA
TTACCAACAGATGTCAGATGCGAAGGCAAACGGCCGGACAAGTAGCAAAGCGAAGAGCAAAAGCAAACACAAACAGAACTCAGAGGCCCT
GATTGCAAATGATGAGTTAGATTACTCTCCAGAGTAGGAGAAACACACAAGTGGGTAGAAATGGTGATGACTGATTTTCAGTAACTTAAC
CTGTGGGCTAGAAGGTGAAAACTTTTTTGGCTCTCATTTCACAAATCCAGCCTTCCCCAAATTCAATCCCTAGTCATAGCCTGTCATTTG
CTACTTTTGCTCTTCAGGATAGTTCTGTTGAAGGGCTTAACCTGGGTCCCCTAACTGGTCGCCTTGTTAAATAAAATAAATAAATAAACA
AGAGGCTATATGAAATTCCATCTTAGGTGCAACCACCAGAGCTGATGGTACCAAATGTTTCCTAGGCCTTTGCTTTGCTGGTTGAAGCCC
AAGCAGGGGCTCTGGGCAGAAGGCAGAATTTCAGTCACCTGAGACATGGGGACAAAGCTCTGTTCTTGGCATGTCAGGCTGAGTGCTGCT
CCCCGAGGTCAGGGTGGGTAGATGGGCATTGGCACTTCCTGAGCAAGCATCATTTTATCCTGCAATCTCACCCAAAATTAATTCATGGAA
AAGACACATGCTTCTTTTTATTCACCAACATTCTCACAGCTTCCAAACTATAATTTTAGGATCCAGCAAAGTTCAGGGACTCTGGACCAT
TTTCCCAATGGTTTCAGATTCACCATAAAGCAGTCAGGCAGACCCAGTGATATGGTAAGAAGCACCATCAAAGCTCTATGTAAATGCCCA
GAAGAAAATTAAATAACCATATCTTGCGGTAAAAGCCAGAAGGGCATTGGCAGAAATTAACTCTCTGTCATGGCCTCTCTTATATCAGAC
TGCAGCTCCTGGTGATATGATGAAAGCGGGCAAAGGTGGAGCATGATTTCATGGCACTGATATGCCTTGAAAAAGTAGGTTGTTTGTTTT
ATAATCAGATAAAAATTTTTACAAGGAGAAGTGAGCCAGCCACTGAGATCACATTGCAAATTCTCTTTCATATTTCTAAAATTATAAATT
CTAAAGTTTTTGAGATAGGCAACCACTTGATTGGTGTGTGCTACTCTGAAAACAAAATAGGCTGAAGTATAGCGACTTAGGTAGTTGCAT
TCCATGAGATCACATTTCACTTCTGAACCTTATTCCTTGGGGCTAGCTCACTTTCAGAGGTGTATTTTTTTTTCCTGTTATTTCCCAGAG
TAGTTTCACTGAAGCCCAGAGAAATATCTACCTGGTAAGATGTAAATTTGGGCCATAAAAGGGGCTATTAAAAGAATTTTCTCAGAAATA
GAATAGATGAGAGAATTTGCAAAGGAAAAAAACACACATGGGCTACAATATAAATTCTACTCTTGGGTTACAAGAATTCCTGTGGCTGCA
CTGAGATACGTACAAATGTATGTGAAGGCACAATTTGAATCAAGCTATCATAGAATTAACCAAGCTATTAAAATTAATCAAGCTATTAAT
AAAATCTCTGTGAGGATTTCCTGAAAGAGGGACAAAAGAAGAAATTCCTTGTCCTTTCTCTCCTGGATGTATCAGTATGCCAAACGTTTT
CCAGAACATATTCGCTAGCACTCAAGTCTGTTCTTTCTGAAAGGCTGAGGCTCATGCCATCTTGGCATGCTTTAGGATTATGGCAAGGAG
GTAAAAGTCCATTTTTTCATTCAACTAACACTGGTTGAGAATAGACCCAATGCTAAGTGACAGGAATGAATAGAAGCATGGCACTTGCCC
TTGGGGGCTACAGTCCATGGATGAGCAGCACTGGAGCCTGGTAAATGCAGATAAAACAACAAACTTGACAAGTCTCCAGGCTGATGCACT
GGGTTTTAACATACATATAAAGATGAATTGAAACTAGTTTTTAAAAAATATGCTTTAAATAAATTACATATCGTAATCATAGCCAATGTA
TACCATTAAACTAAAATAACTGCAATTTTCTAGATATTTTTTATTCTTCTGTAGTCATTGTTTAGAACTCTGGTTTCCTGAGGTCATTTT
GTCATTTTAATATCATGCTTGACAATGCTATGTTTTCTCTTCCCTAGAGTTAACCATAAAGATACAGTGCCTACTCTGTGAAATACAGCA
TTAGGAATTAATTATAAACTAATTATCAGTCATCTTTTGAAAACAAAGTTTTGAATTGGCTATAGGACTCAACAAATCTGCCTGGTGTAA
ATAGAATCTGTTAAGCTTGATACATATCTAGATAGATGAGGAGGGGTTGTATTCATTAAGCATGAGAATAGAGAAATAGGAGTGCAAAAT
GGCAAAATCTTAACGTGGGTGAAAGAGCTTCCTTTTACTAGTGAGGTTTAAGTATTAAAGTAACAATAGCCTGGTGGCAGATGAATGCAA
TTTCTATAGGATGGGAATGGAAAATGTATGCTTTGGTTAACACCATTGCTGTTGACTTCATGCAGATTCTATTAAGCACTCTCATTTCAG
GAGCCATTTTTCCCACATAGTATATTAGTATATTTTAAGCTTAGCTCCCTTTATTTTTCTAAAGTTGATAAATCACCTCCCTAGCAACCT
TAGTTTTAAAAAAAAAATCACTAAGATAGAAAAAGTATTTTCAGGTACATAGACATGTTTGTCCTCAGGTTTACCTGCTTCTGTGAACAG
TCCCAGATTTTACAATGCAGTTTTCAAATACCATCAATCACTACAATGACAATATTACTATTTTCTTAACAGGTTTCTAAACGATGTATG
TGTGGGATCACATTAAAAGTAAGATCACCTTATAATTATCTTAGAAACTTTGCCCCTTGAAGGGAGTCCAAGGAAGACCTACATTTTATT
GAATTCTGAATAGCAAAAGCTCTCCGAGTGAGATTTCATTGTGTGGATTTGTGGTTTGGAGCCAATTACTTGATTTTCTTCAGATTTTAT
TCTACTTATTTATTGGTACTCTGCTTCATTTCAAAAGGATTTGAGGCAGCTACTAAAATATATATAATACAAAACAAAAATTAAGTGAGG
AACTCAGAGCAAACAAAAATAGAAACAGAAAGGATAAGACAAAACTAGACGTATATTTAGTACATAAATGCAGAACCCTGACATGCTTTA
CTAAATTTGCCAATGAGTGACACCATGAAAAATAATAGAATTAGTGGTAATGACAAGAAGAAGTACTTCTGCATGATAAGAACAAATCTT
TCCCCATGCAGGTAGAGGTTTGAAATAGCATAGATCATTAAAATCCACAGGTAAGCTTCAAACCTAGATTTTGCTAGCTACATGTGCCTG
GCATATAGTGTGTATTCAAGAAATACCTGATGATTGACAGAATGAATGAATTGGAGGAAAATGAAATATTTATTCAACAATTACTTGTGG
AGTGCCTATTATGTACTATGGCAGATATTGATATCGTAAGTCAGATAAAAATCCAGCTCTTAAGAAGTAGAGGAAATAGAGCTTGGTGTG
GTGGCATGTGCCTATGATCCCAGATAGTTGAGAGACTGAGGGAGGAGGATCACTTGAGCCCAGGAGTTCAAGGCTGCAGTGAGCTATGAT
CACACCACTGTACTCCAGCCTGGGTAACAGAAGAATACCCTGTCTCTTAAAAAGGAAAATCAAATAGGGGAAATGGGATATATAAATAAA
GAACAATAGTGAATGTGTCAGGTGAGATGACGGACTTGTAATGTGCTGTGGGGGGTCAAATATGAAGAAGGCCTTCTTCCTCTGGAAAGG
TCATAAAGAATGTCACACTTGTGTTGGAACTTGTGAAGTGGGTAGAATTTTATCAAGTAGAAATGAGAGAAAGGCATGCCAAGCAAAGGA
TCGGCATGAATAAGGTCTACTAGTTTGTGGTCCTCTGGCTAAGAATTTGTGCTGTGCCTCCATTAAGAGAAAGCAAGGAGCTAGTTTGCC
TGGAGCACATGATTTATGCATGACTTATACATGCAACAATAAGAAATAATGCTAGGAAGGCAGGTGAGGGATCACTCACAGAGAGACTTG
AATGTCACACTGAGCTGACTGGCTTTCCTCGGGTGAGAGAGTGGGAAATAATTGGGGAACTGACGAAAGTGTGAATCCAGGAAGGCTGAA
CTTTAAGAAAGCTGAGACGGTGGCTTCCTTACCTATGCAAGGAACTAACAAGCCACATATACACTCCAAATTGATTTAACAAATTAAAGA
GAAAAATAGCTGTACTTTGAGTCCTGTGTCTGCATTCATCATTAACCTAAGAAAATACAGCCATTTAATACGTGGACAAGCAACACAATT
TAACAGCCACTTTAAAGTTTTCAACAATAGGTTTCAACAACTAAACCTAACAACTTTTTATATCTATCTAATCTAAACAGTAAAATCTCA
GCTCCAGGTTTTACTGAGCTTGAGTGCTACTTTTTTTTTTTTAGACAGAGTCTCATTCTGTCACCCAGGCTGGAGTGCAGTGGCATGATC
TTGGCTCACTGCAACCTTCACCTCCCGGGTTCAAGCTATTCTCCTGCCTCAGCCTCCCAAGCAGCTGGGATTATAGGCGTGTGCCAGTTC
TACTTCTTAGTAACAAACTAGTAGCTAATCAAATGCCTACATAATGGTCATGATAAATCTGTTTAAATAAATGGCGGGCGGAAGGGAGTT
GTTGAATTTAACAATCCATCCTTCTTCAGAATCTATAGGTCAGCCAGAATATAAATCTAGTAATTATTGAAAAACAAAACACAAACTCCT
TCAAAGAAATCTCTCTCCTCTATTCTGCTGAAAAGGGTTGGTAAACCTGACATCCTTTCTTTTATTGGAAGACAAATCCAACATTTGTTA
GACATCCAACATTTGTTGGAAGTCTACCTTACAAGAAACCACCTCTTATCTGCAACATAAACAGAAGCTACATCAGGTTGAAAATCCACA
TAGAAGACTGGAGAAAATTGCCGTCCCCTTTCGCACTAGGTTTTACCAGGGGCCCAAGATGTCAGAGGAAAGTCCGCGGAGGGCCAAACA
CAGGTTTACCTAATTATGAATCTCAGATTAGAATGTCTTATTGTGTGGAAAAGTCAGAACTCAGGAAATGTGTCTGAAGCCAGAGCGGGG
GTCTGCTTACGGAGTCTACGCAGCGGGTAGGGGTCCACTATTGGAGTATAAACCTCAGGTCAGTGAGTAGTGCAGAGGTGTCCCTAACTT
CCAATGGAGGGAAAGAGAGGAGAGCAAAGGAAACACATCCAGAAGTCGCCACGAGGGCTGTGTGCCAGCGCTCCATTTTCATGCTGTTTG
GAACAAGACGTGTCAAGGAAGATGTTTCTATCCAAAGTCTTCATGGAGCCTCTGCTTCCCCTGTACCTGTGTAGCTCCCTGAAACTGAGG
ACCCACGTGTCTGCAAAGACCTCTGGAGATCCTAAGAGAGAGAGGCACCAGCAGGTAACCAGTGGTGGCCTGGCCACGAAAGAGTATTTG
AAATTCAACAGTGAGCAAGTGCAGAAACAGCATCCCAAACCGCAGGCCCCACCACACGCAGGAACCAGAAAGCTGAAGTTTCACCAAGGA
GTTTACTTAGTATTTCTCGCTGGGAATGGGGATGGGTAGCAAAAAGCCCCTTTCATGTACATAATGGTTGGTCCTATGTCCTACTTTTAT
TTTCTCTAAGAGTTTTAGAAGAAAGGCTGTTTTAATTTTTTTTTCTCCTTAAGAGCAACTTCCTTTTTAAAATGCTTTCCTCTTCTTGTC
CTGCTTGAGTAATGCAGGCATCATTCTGAAATCATTCTGAAACAGCTAGGCAGTCGCCTTTTGCCAAAATTACTTCTCTAAGAAAATAGA
GTGTTCTTTTTTTTAGGACTTAGAACCCACAAGGGGTGAGTGGAAGTTTTGTAGCCCATCAAAGGTGAATATGTGTTCTGCAGTATCAAC
TAAAACAGTGTACAAAATCATTAAACTGGGCCGGGCGCAGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGTGGATC
ACCTGAGGCCAGGAGTTCAAGACCAGCCTGACCAACATGGAGAAACCCCATCTCTACTAAAAATACAAAATTAGCCAGGTGTGGTGTTGC
ATGCCTGTAATCCCAGCTATTAGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGGAGGCAGAGGTTGCAGTGAGTCGAGATCACACCA
TTGCACTCCAGCCTGGGCAATAAGAGCAAAACTCCGTCTCAAAAATAATAATAATAATAATTTAACTGTGTTCTGCACACACAGAATTAC
AAAATCCCTATAGGACTTTCACAGATAGCTTTGGGCTTAAGGTCTTCGGACAACAGGTAGTTCTAATTTCTTACTCTTTGGGACATTTAG
TACATGTTGGTACACATAAGGAAAGAAAATGGCTTATATTAGAGCTAGGAAACAGGGGCAGCCTGGATTTTTATGGTAGGAACTCACTCT
GTGCTTTTTTTTTTTTCTGTTAAGTTTTCTTGACACTGACTTCGGTAACATTGGCTAAAGGGAATTGTGAGTCATGTGAATTTCACCTGC
AGTGCAGACTTTAAAGGACTGTGTTCATTCTGATTTGGGGATGAAGAGAATGTTCCATGCACATCTATTGATTGGTCTTGGCAGTTGCTG
ATACGCTTGTCTCATTCACACTCCCAAAGGCGAGGATTTACCCTAGAAATCATAAACCCCCACTTTCCAAAGCAAAGATGCTGTTAATGT
TATGATGGTGCATAAATACCTCAACTGTCTGGGCTGAGAGAGGGGGCTGCAGGTTTTTAAGAGAGCAGCTATAGTCCTCATTCCATGTAG
TCACATCATCTGATGACAGGACTCCACATTCTAGCTTTTCTCACTGTGGAAAAGAAACGTTACTGTTTAATTAATATCCAAAGTTATAAA
TACAGCTTGTAAATTTTACTAACTTGTTTCTTTTTCGTTTCGTCCTTGAGAAGTACAACTTGCATTTACAGATGGTAATTCCTAGTGTTG
TTCTCTGCTATCTTTTTTTGGTATGAAATTGCTGTATTTGTTAAAGTTTGTTCGTTTTGTGGTTTTTAATTCCCATTGGTGTGCTGTACA
ATGTAGTGTATCATGAAGAAAGAAATAATATGCAGATGTATTATGAAATGTGTTTTATTTTCAAATGTGTGGTGTTGACAATATATTGAT
TTATCAAGATACTAAGGGAAAATTCTAAATTTAACAAAATGTGTATATTTTAATAAATGCATAAAGCTTTATTGTGTGCCTTTAAATTTA
AAAATGGGTTTATAAAGAAAGTCAGAAACAAAAGTGTCTTACTATAAAATATCCATAGTAATGTAAAGCTTTTACACGAGACTACCAAAA
AAAAAGAAAGAAAAGAAAAAGGAGCCTTCCCATATTTTGTTAACCTTAACCAGTATCTGAAGTCTGTTACTTTTTTTCCATTCTTAAATG
GAGATGAATAAGTGAATTTCGCCTTAAGTGTTTCAATTGTCCTTTGTAGAAAAGCCAGATAAATGAGTTCACTTTGAATTGCATTATTGT


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FusionGenePPI for PHC3_SLC7A14


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
PHC3PCGF2, BMI1, RNF2, PHC1, PHC2, RING1, CBX2, CBX4, CBX6, CBX8, SCMH1, SCML1, ALB, SOX2, OGT, HIST3H3, EED, CBX7, DDI1, C11orf30, ZNF131, TRIM25SLC7A14


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for PHC3_SLC7A14


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for PHC3_SLC7A14


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneSLC7A14C3810380RETINITIS PIGMENTOSA 681UNIPROT