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Fusion gene ID: 26399 |
FusionGeneSummary for PDE4D_DEPDC1B |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PDE4D_DEPDC1B | Fusion gene ID: 26399 | Hgene | Tgene | Gene symbol | PDE4D | DEPDC1B | Gene ID | 5144 | 55789 |
| Gene name | phosphodiesterase 4D | DEP domain containing 1B | |
| Synonyms | ACRDYS2|DPDE3|HSPDE4D|PDE43|PDE4DN2|STRK1 | BRCC3|XTP1 | |
| Cytomap | 5q11.2-q12.1 | 5q12.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | cAMP-specific 3',5'-cyclic phosphodiesterase 4DcAMP-specific phosphodiesterase PDE4D6phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila)testicular tissue protein Li 136 | DEP domain-containing protein 1BHBV X-transactivated gene 8 proteinHBV XAg-transactivated protein 8HBxAg transactivated protein 1breast cancer cell 3 | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | Q08499 | Q8WUY9 | |
| Ensembl transtripts involved in fusion gene | ENST00000340635, ENST00000360047, ENST00000507116, ENST00000502484, ENST00000546160, ENST00000502575, ENST00000358923, ENST00000503258, ENST00000405755, ENST00000317118, ENST00000503947, | ENST00000265036, ENST00000453022, ENST00000545085, ENST00000509006, | |
| Fusion gene scores | * DoF score | 23 X 14 X 10=3220 | 2 X 4 X 4=32 |
| # samples | 34 | 8 | |
| ** MAII score | log2(34/3220*10)=-3.24345403686428 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(8/32*10)=1.32192809488736 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: PDE4D [Title/Abstract] AND DEPDC1B [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | PDE4D | GO:0006198 | cAMP catabolic process | 9371713|17404263 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LUAD | TCGA-44-7660-01A | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| TCGA | RV | LUSC | TCGA-39-5029-01A | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| TCGA | RV | LUSC | TCGA-77-8143-01A | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| TCGA | RV | PRAD | TCGA-KK-A8IM-01A | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| TCGA | RV | PRAD | TCGA-EJ-5521-01A | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| TCGA | RV | PRAD | TCGA-CH-5750-01A | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| TCGA | RV | PRAD | TCGA-VN-A88O-01A | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000340635 | ENST00000265036 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-3CDS | ENST00000340635 | ENST00000453022 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-5UTR | ENST00000340635 | ENST00000545085 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-intron | ENST00000340635 | ENST00000509006 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-3CDS | ENST00000360047 | ENST00000265036 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-3CDS | ENST00000360047 | ENST00000453022 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-5UTR | ENST00000360047 | ENST00000545085 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-intron | ENST00000360047 | ENST00000509006 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-3CDS | ENST00000507116 | ENST00000265036 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-3CDS | ENST00000507116 | ENST00000453022 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-5UTR | ENST00000507116 | ENST00000545085 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-intron | ENST00000507116 | ENST00000509006 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| 5UTR-3CDS | ENST00000502484 | ENST00000265036 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| 5UTR-3CDS | ENST00000502484 | ENST00000453022 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| 5UTR-5UTR | ENST00000502484 | ENST00000545085 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| 5UTR-intron | ENST00000502484 | ENST00000509006 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-3CDS | ENST00000546160 | ENST00000265036 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-3CDS | ENST00000546160 | ENST00000453022 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-5UTR | ENST00000546160 | ENST00000545085 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-intron | ENST00000546160 | ENST00000509006 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-3CDS | ENST00000502575 | ENST00000265036 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-3CDS | ENST00000502575 | ENST00000453022 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-5UTR | ENST00000502575 | ENST00000545085 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-intron | ENST00000502575 | ENST00000509006 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-3CDS | ENST00000358923 | ENST00000265036 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-3CDS | ENST00000358923 | ENST00000453022 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-5UTR | ENST00000358923 | ENST00000545085 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-intron | ENST00000358923 | ENST00000509006 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-3CDS | ENST00000503258 | ENST00000265036 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-3CDS | ENST00000503258 | ENST00000453022 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-5UTR | ENST00000503258 | ENST00000545085 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-intron | ENST00000503258 | ENST00000509006 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-3CDS | ENST00000405755 | ENST00000265036 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-3CDS | ENST00000405755 | ENST00000453022 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-5UTR | ENST00000405755 | ENST00000545085 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-intron | ENST00000405755 | ENST00000509006 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-3CDS | ENST00000317118 | ENST00000265036 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-3CDS | ENST00000317118 | ENST00000453022 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-5UTR | ENST00000317118 | ENST00000545085 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-intron | ENST00000317118 | ENST00000509006 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-3CDS | ENST00000503947 | ENST00000265036 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-3CDS | ENST00000503947 | ENST00000453022 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-5UTR | ENST00000503947 | ENST00000545085 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-intron | ENST00000503947 | ENST00000509006 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-3CDS | ENST00000340635 | ENST00000265036 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000340635 | ENST00000453022 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000340635 | ENST00000545085 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-intron | ENST00000340635 | ENST00000509006 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000360047 | ENST00000265036 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000360047 | ENST00000453022 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000360047 | ENST00000545085 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-intron | ENST00000360047 | ENST00000509006 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000507116 | ENST00000265036 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000507116 | ENST00000453022 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000507116 | ENST00000545085 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-intron | ENST00000507116 | ENST00000509006 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| 5UTR-3CDS | ENST00000502484 | ENST00000265036 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| 5UTR-3CDS | ENST00000502484 | ENST00000453022 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| 5UTR-3CDS | ENST00000502484 | ENST00000545085 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| 5UTR-intron | ENST00000502484 | ENST00000509006 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000546160 | ENST00000265036 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000546160 | ENST00000453022 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000546160 | ENST00000545085 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-intron | ENST00000546160 | ENST00000509006 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000502575 | ENST00000265036 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000502575 | ENST00000453022 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000502575 | ENST00000545085 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-intron | ENST00000502575 | ENST00000509006 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000358923 | ENST00000265036 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000358923 | ENST00000453022 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000358923 | ENST00000545085 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-intron | ENST00000358923 | ENST00000509006 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000503258 | ENST00000265036 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000503258 | ENST00000453022 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000503258 | ENST00000545085 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-intron | ENST00000503258 | ENST00000509006 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000405755 | ENST00000265036 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000405755 | ENST00000453022 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000405755 | ENST00000545085 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-intron | ENST00000405755 | ENST00000509006 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000317118 | ENST00000265036 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000317118 | ENST00000453022 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000317118 | ENST00000545085 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-intron | ENST00000317118 | ENST00000509006 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000503947 | ENST00000265036 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000503947 | ENST00000453022 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000503947 | ENST00000545085 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-intron | ENST00000503947 | ENST00000509006 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000340635 | ENST00000265036 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-3CDS | ENST00000340635 | ENST00000453022 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-5UTR | ENST00000340635 | ENST00000545085 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-intron | ENST00000340635 | ENST00000509006 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-3CDS | ENST00000360047 | ENST00000265036 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-3CDS | ENST00000360047 | ENST00000453022 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-5UTR | ENST00000360047 | ENST00000545085 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-intron | ENST00000360047 | ENST00000509006 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-3CDS | ENST00000507116 | ENST00000265036 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-3CDS | ENST00000507116 | ENST00000453022 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-5UTR | ENST00000507116 | ENST00000545085 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-intron | ENST00000507116 | ENST00000509006 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| Frame-shift | ENST00000502484 | ENST00000265036 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| Frame-shift | ENST00000502484 | ENST00000453022 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| 5CDS-5UTR | ENST00000502484 | ENST00000545085 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| 5CDS-intron | ENST00000502484 | ENST00000509006 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| In-frame | ENST00000546160 | ENST00000265036 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| In-frame | ENST00000546160 | ENST00000453022 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| 5CDS-5UTR | ENST00000546160 | ENST00000545085 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| 5CDS-intron | ENST00000546160 | ENST00000509006 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-3CDS | ENST00000502575 | ENST00000265036 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-3CDS | ENST00000502575 | ENST00000453022 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-5UTR | ENST00000502575 | ENST00000545085 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-intron | ENST00000502575 | ENST00000509006 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-3CDS | ENST00000358923 | ENST00000265036 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-3CDS | ENST00000358923 | ENST00000453022 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-5UTR | ENST00000358923 | ENST00000545085 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-intron | ENST00000358923 | ENST00000509006 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-3CDS | ENST00000503258 | ENST00000265036 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-3CDS | ENST00000503258 | ENST00000453022 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-5UTR | ENST00000503258 | ENST00000545085 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-intron | ENST00000503258 | ENST00000509006 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-3CDS | ENST00000405755 | ENST00000265036 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-3CDS | ENST00000405755 | ENST00000453022 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-5UTR | ENST00000405755 | ENST00000545085 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-intron | ENST00000405755 | ENST00000509006 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-3CDS | ENST00000317118 | ENST00000265036 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-3CDS | ENST00000317118 | ENST00000453022 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-5UTR | ENST00000317118 | ENST00000545085 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-intron | ENST00000317118 | ENST00000509006 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-3CDS | ENST00000503947 | ENST00000265036 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-3CDS | ENST00000503947 | ENST00000453022 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-5UTR | ENST00000503947 | ENST00000545085 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-intron | ENST00000503947 | ENST00000509006 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59983054 | - |
| intron-3CDS | ENST00000340635 | ENST00000265036 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000340635 | ENST00000453022 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000340635 | ENST00000545085 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-intron | ENST00000340635 | ENST00000509006 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000360047 | ENST00000265036 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000360047 | ENST00000453022 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000360047 | ENST00000545085 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-intron | ENST00000360047 | ENST00000509006 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000507116 | ENST00000265036 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000507116 | ENST00000453022 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000507116 | ENST00000545085 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-intron | ENST00000507116 | ENST00000509006 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| In-frame | ENST00000502484 | ENST00000265036 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| In-frame | ENST00000502484 | ENST00000453022 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| In-frame | ENST00000502484 | ENST00000545085 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| 5CDS-intron | ENST00000502484 | ENST00000509006 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| Frame-shift | ENST00000546160 | ENST00000265036 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| Frame-shift | ENST00000546160 | ENST00000453022 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| Frame-shift | ENST00000546160 | ENST00000545085 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| 5CDS-intron | ENST00000546160 | ENST00000509006 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000502575 | ENST00000265036 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000502575 | ENST00000453022 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000502575 | ENST00000545085 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-intron | ENST00000502575 | ENST00000509006 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000358923 | ENST00000265036 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000358923 | ENST00000453022 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000358923 | ENST00000545085 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-intron | ENST00000358923 | ENST00000509006 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000503258 | ENST00000265036 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000503258 | ENST00000453022 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000503258 | ENST00000545085 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-intron | ENST00000503258 | ENST00000509006 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000405755 | ENST00000265036 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000405755 | ENST00000453022 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000405755 | ENST00000545085 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-intron | ENST00000405755 | ENST00000509006 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000317118 | ENST00000265036 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000317118 | ENST00000453022 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000317118 | ENST00000545085 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-intron | ENST00000317118 | ENST00000509006 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000503947 | ENST00000265036 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000503947 | ENST00000453022 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000503947 | ENST00000545085 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-intron | ENST00000503947 | ENST00000509006 | PDE4D | chr5 | 59481384 | - | DEPDC1B | chr5 | 59943360 | - |
| intron-3CDS | ENST00000340635 | ENST00000265036 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| intron-intron | ENST00000340635 | ENST00000453022 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| intron-intron | ENST00000340635 | ENST00000545085 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| intron-intron | ENST00000340635 | ENST00000509006 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| intron-3CDS | ENST00000360047 | ENST00000265036 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| intron-intron | ENST00000360047 | ENST00000453022 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| intron-intron | ENST00000360047 | ENST00000545085 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| intron-intron | ENST00000360047 | ENST00000509006 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| intron-3CDS | ENST00000507116 | ENST00000265036 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| intron-intron | ENST00000507116 | ENST00000453022 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| intron-intron | ENST00000507116 | ENST00000545085 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| intron-intron | ENST00000507116 | ENST00000509006 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| 5UTR-3CDS | ENST00000502484 | ENST00000265036 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| 5UTR-intron | ENST00000502484 | ENST00000453022 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| 5UTR-intron | ENST00000502484 | ENST00000545085 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| 5UTR-intron | ENST00000502484 | ENST00000509006 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| intron-3CDS | ENST00000546160 | ENST00000265036 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| intron-intron | ENST00000546160 | ENST00000453022 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| intron-intron | ENST00000546160 | ENST00000545085 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| intron-intron | ENST00000546160 | ENST00000509006 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| intron-3CDS | ENST00000502575 | ENST00000265036 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| intron-intron | ENST00000502575 | ENST00000453022 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| intron-intron | ENST00000502575 | ENST00000545085 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| intron-intron | ENST00000502575 | ENST00000509006 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| intron-3CDS | ENST00000358923 | ENST00000265036 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| intron-intron | ENST00000358923 | ENST00000453022 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| intron-intron | ENST00000358923 | ENST00000545085 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| intron-intron | ENST00000358923 | ENST00000509006 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| intron-3CDS | ENST00000503258 | ENST00000265036 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| intron-intron | ENST00000503258 | ENST00000453022 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| intron-intron | ENST00000503258 | ENST00000545085 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| intron-intron | ENST00000503258 | ENST00000509006 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| intron-3CDS | ENST00000405755 | ENST00000265036 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| intron-intron | ENST00000405755 | ENST00000453022 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| intron-intron | ENST00000405755 | ENST00000545085 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| intron-intron | ENST00000405755 | ENST00000509006 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| intron-3CDS | ENST00000317118 | ENST00000265036 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| intron-intron | ENST00000317118 | ENST00000453022 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| intron-intron | ENST00000317118 | ENST00000545085 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| intron-intron | ENST00000317118 | ENST00000509006 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| intron-3CDS | ENST00000503947 | ENST00000265036 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| intron-intron | ENST00000503947 | ENST00000453022 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| intron-intron | ENST00000503947 | ENST00000545085 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
| intron-intron | ENST00000503947 | ENST00000509006 | PDE4D | chr5 | 59783769 | - | DEPDC1B | chr5 | 59895087 | - |
Top |
FusionProtFeatures for PDE4D_DEPDC1B |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| PDE4D | DEPDC1B |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
Top |
FusionGeneSequence for PDE4D_DEPDC1B |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_PDE4D_ENST00000546160_chr5_59481384_-_DEPDC1B_ENST00000265036_chr5_59983054_-_528aa MKRNTCDLLSRSKSWNETVELFRAKMPLRKHRCRFKSYEHCFTAAEAVDWLHELLRCSQNFGPEVTRKQTVQLLKKFLKNHVIEDIKGKW GEEDFEDNRHLYRFPPSSPLKPYPKKPPNQKDVIKFPEWNDLPPGTSQENIPVRPVVMNSEMWYKRHSIAIGEVPACRLVHRRQLTEANV EEIWKSMTLSYLQKILGLDSLEEVLDVKLVNSKFIIHNVYSVSKQGVVILDDKSKELPHWVLSAMKCLANWPNCSDLKQPMYLGFEKDVF KTIADYYGHLKEPLLTFHLFDAFVSVLGLLQKEKVAVEAFQICCLLLPPENRRKLQLLMRMMARICLNKEMPPLCDGFGTRTLMVQTFSR CILCSKDEVDLDELLAARLVTFLMDNYQEILKVPLALQTSIEERVAHLRRVQIKYPGADMDITLSAPSFCRQISPEEFEYQRSYGSQEPL >In-frame_PDE4D_ENST00000546160_chr5_59481384_-_DEPDC1B_ENST00000453022_chr5_59983054_-_466aa MKRNTCDLLSRSKSWNETVELFRAKMPLRKHRCRFKSYEHCFTAAEAVDWLHELLRCSQNFGPEVTRKQTVQLLKKFLKNHVIEDIKGKW GEEDFEDNRHLYRFPPSSPLKPYPKKPPNQKDVIKFPEWNDLPPGTSQENIPVRPVVMNSEMWYKRHSIAIGEVPACRLVHRRQLTEANV EEIWKSMTLSYLQKILGLDSLEEVLDVKLVNSKFIIHNVYSVSKQGVVILDDKSKELPHWVLSAMKCLANWPNCSDLKQPMYLGFEKDVF KTIADYYGHLKEPLLTFHLFDAFVSVLGLLQKEKVAVEAFQICCLLLPPENRRKLQLLMRMMARICLNKEMPPLCDGFGTRTLMVQTFSR CILCSKDEVDLDELLAARLVTFLMDNYQEILKVPLALQTSIEERVAHLRRVQFQKSYPEVYQERFPTPESAALLFPEKPKPKPQLLMWAL >In-frame_PDE4D_ENST00000502484_chr5_59481384_-_DEPDC1B_ENST00000265036_chr5_59943360_-_439aa MKRNTCDLLSRSKSISSFFTPETISKEAPKPKGCYXISRMEXSPTRHFTREHPSEASCDEFXDVVQASQYCNWRGASLPSCPPQTADRGQ CRRDMEVYDIIILTENSWPGFLRRSFRRQTCQFEVHHPXCIXCXQAGSCYSXXQVKRTSSLGAVSYEVFGKLAQLFXFEAAYVLGIXKRC LXNHSXLLWSLERASTYISSFXCFCQCTGFVTEGESGSXSISDLLPSPTSXKXEKVTAIDEDDGKDLLKQRDATPVXWLWYPNTDGSDIF PLHLVFQGXSGLGXVISCXIGNVSDGQLPGNSESPFGLADLYRGACGSSTKSPDKIPRSXYGYHFICSIILPSNXSRGIXISKIIWLSGT >In-frame_PDE4D_ENST00000502484_chr5_59481384_-_DEPDC1B_ENST00000453022_chr5_59943360_-_377aa MKRNTCDLLSRSKSISSFFTPETISKEAPKPKGCYXISRMEXSPTRHFTREHPSEASCDEFXDVVQASQYCNWRGASLPSCPPQTADRGQ CRRDMEVYDIIILTENSWPGFLRRSFRRQTCQFEVHHPXCIXCXQAGSCYSXXQVKRTSSLGAVSYEVFGKLAQLFXFEAAYVLGIXKRC LXNHSXLLWSLERASTYISSFXCFCQCTGFVTEGESGSXSISDLLPSPTSXKXEKVTAIDEDDGKDLLKQRDATPVXWLWYPNTDGSDIF PLHLVFQGXSGLGXVISCXIGNVSDGQLPGNSESPFGLADLYRGACGSSTKSPVSEILSXSLSRTISYTRKCSTSVSXKTQTETTAANVG >In-frame_PDE4D_ENST00000502484_chr5_59481384_-_DEPDC1B_ENST00000545085_chr5_59943360_-_377aa MKRNTCDLLSRSKSISSFFTPETISKEAPKPKGCYXISRMEXSPTRHFTREHPSEASCDEFXDVVQASQYCNWRGASLPSCPPQTADRGQ CRRDMEVYDIIILTENSWPGFLRRSFRRQTCQFEVHHPXCIXCXQAGSCYSXXQVKRTSSLGAVSYEVFGKLAQLFXFEAAYVLGIXKRC LXNHSXLLWSLERASTYISSFXCFCQCTGFVTEGESGSXSISDLLPSPTSXKXEKVTAIDEDDGKDLLKQRDATPVXWLWYPNTDGSDIF PLHLVFQGXSGLGXVISCXIGNVSDGQLPGNSESPFGLADLYRGACGSSTKSPVSEILSXSLSRTISYTRKCSTSVSXKTQTETTAANVG |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_PDE4D_ENST00000546160_chr5_59481384_-_DEPDC1B_ENST00000265036_chr5_59983054_-_1584nt ATGAAAAGAAATACCTGTGATTTGCTTTCTCGGAGCAAAAGTTGGAATGAGACCGTGGAGCTTTTTCGTGCTAAGATGCCGTTACGGAAA CATCGCTGTCGTTTCAAGAGCTATGAGCATTGTTTCACAGCGGCCGAAGCTGTGGATTGGCTGCATGAGCTGCTGAGGTGCAGTCAAAAC TTCGGCCCTGAAGTGACCCGCAAACAAACGGTCCAGCTGCTAAAAAAATTCCTGAAGAATCACGTTATTGAAGACATCAAGGGAAAATGG GGTGAGGAAGATTTTGAAGACAATCGTCACTTATACAGATTTCCTCCTTCTTCACCCCTGAAACCATATCCAAAGAAGCCCCCAAACCAA AAGGATGTTATTAAATTTCCAGAATGGAATGATCTCCCACCAGGCACTTCACAAGAGAACATCCCAGTGAGGCCAGTTGTGATGAATTCT GAGATGTGGTACAAGCGTCACAGTATTGCAATTGGAGAGGTGCCAGCTTGCCGTCTTGTCCACCGCAGACAGCTGACAGAGGCCAATGTA GAAGAGATATGGAAGTCTATGACATTATCATACTTACAGAAAATTCTTGGCCTGGATTCCTTAGAAGAAGTTTTAGACGTCAAACTTGTC AATTCGAAGTTCATCATCCATAATGTATATAGTGTTAGCAAGCAGGGAGTTGTTATTCTTGATGACAAGTCAAAAGAACTTCCTCATTGG GTGCTGTCAGCTATGAAGTGTTTGGCAAATTGGCCCAACTGTTCTGATTTGAAGCAGCCTATGTACTTGGGATTTGAAAAAGATGTCTTT AAAACCATAGCTGATTACTATGGTCACTTGAAAGAGCCTCTACTTACATTTCATCTTTTTGATGCTTTTGTCAGTGTACTGGGTTTGTTA CAGAAGGAGAAAGTGGCAGTTGAAGCATTTCAGATTTGCTGCCTTCTCCTACCTCCTGAAAATAGGAGAAAGTTACAGCTATTGATGAGG ATGATGGCAAGGATTTGCTTAAACAAAGAGATGCCACCCCTGTGTGATGGCTTTGGTACCCGAACACTGATGGTTCAGACATTTTCCCGT TGCATCTTGTGTTCCAAGGATGAAGTGGACTTGGATGAGTTATTAGCTGCTAGATTGGTAACGTTTCTGATGGACAATTACCAGGAAATT CTGAAAGTCCCTTTGGCCTTGCAGACCTCTATAGAGGAGCGTGTGGCTCATCTACGAAGAGTCCAGATAAAATACCCAGGAGCTGATATG GATATCACTTTATCTGCTCCATCATTTTGCCGTCAAATTAGTCCAGAGGAATTTGAATATCAAAGATCATATGGCTCTCAGGAACCTCTG GCAGCCTTGTTGGAGGAAGTCATAACAGATGCCAAACTCTCCAACAAAGAGAAAAAGAAGAAACTGAAGCAGTTTCAGAAATCCTATCCT GAAGTCTATCAAGAACGATTTCCTACACCAGAAAGTGCAGCACTTCTGTTTCCTGAAAAACCCAAACCGAAACCACAGCTGCTAATGTGG >In-frame_PDE4D_ENST00000546160_chr5_59481384_-_DEPDC1B_ENST00000453022_chr5_59983054_-_1398nt ATGAAAAGAAATACCTGTGATTTGCTTTCTCGGAGCAAAAGTTGGAATGAGACCGTGGAGCTTTTTCGTGCTAAGATGCCGTTACGGAAA CATCGCTGTCGTTTCAAGAGCTATGAGCATTGTTTCACAGCGGCCGAAGCTGTGGATTGGCTGCATGAGCTGCTGAGGTGCAGTCAAAAC TTCGGCCCTGAAGTGACCCGCAAACAAACGGTCCAGCTGCTAAAAAAATTCCTGAAGAATCACGTTATTGAAGACATCAAGGGAAAATGG GGTGAGGAAGATTTTGAAGACAATCGTCACTTATACAGATTTCCTCCTTCTTCACCCCTGAAACCATATCCAAAGAAGCCCCCAAACCAA AAGGATGTTATTAAATTTCCAGAATGGAATGATCTCCCACCAGGCACTTCACAAGAGAACATCCCAGTGAGGCCAGTTGTGATGAATTCT GAGATGTGGTACAAGCGTCACAGTATTGCAATTGGAGAGGTGCCAGCTTGCCGTCTTGTCCACCGCAGACAGCTGACAGAGGCCAATGTA GAAGAGATATGGAAGTCTATGACATTATCATACTTACAGAAAATTCTTGGCCTGGATTCCTTAGAAGAAGTTTTAGACGTCAAACTTGTC AATTCGAAGTTCATCATCCATAATGTATATAGTGTTAGCAAGCAGGGAGTTGTTATTCTTGATGACAAGTCAAAAGAACTTCCTCATTGG GTGCTGTCAGCTATGAAGTGTTTGGCAAATTGGCCCAACTGTTCTGATTTGAAGCAGCCTATGTACTTGGGATTTGAAAAAGATGTCTTT AAAACCATAGCTGATTACTATGGTCACTTGAAAGAGCCTCTACTTACATTTCATCTTTTTGATGCTTTTGTCAGTGTACTGGGTTTGTTA CAGAAGGAGAAAGTGGCAGTTGAAGCATTTCAGATTTGCTGCCTTCTCCTACCTCCTGAAAATAGGAGAAAGTTACAGCTATTGATGAGG ATGATGGCAAGGATTTGCTTAAACAAAGAGATGCCACCCCTGTGTGATGGCTTTGGTACCCGAACACTGATGGTTCAGACATTTTCCCGT TGCATCTTGTGTTCCAAGGATGAAGTGGACTTGGATGAGTTATTAGCTGCTAGATTGGTAACGTTTCTGATGGACAATTACCAGGAAATT CTGAAAGTCCCTTTGGCCTTGCAGACCTCTATAGAGGAGCGTGTGGCTCATCTACGAAGAGTCCAGTTTCAGAAATCCTATCCTGAAGTC TATCAAGAACGATTTCCTACACCAGAAAGTGCAGCACTTCTGTTTCCTGAAAAACCCAAACCGAAACCACAGCTGCTAATGTGGGCACTA >In-frame_PDE4D_ENST00000502484_chr5_59481384_-_DEPDC1B_ENST00000265036_chr5_59943360_-_1318nt ATGAAAAGAAATACCTGTGATTTGCTTTCTCGGAGCAAAAGTATTTCCTCCTTCTTCACCCCTGAAACCATATCCAAAGAAGCCCCCAAA CCAAAAGGATGTTATTAAATTTCCAGAATGGAATGATCTCCCACCAGGCACTTCACAAGAGAACATCCCAGTGAGGCCAGTTGTGATGAA TTCTGAGATGTGGTACAAGCGTCACAGTATTGCAATTGGAGAGGTGCCAGCTTGCCGTCTTGTCCACCGCAGACAGCTGACAGAGGCCAA TGTAGAAGAGATATGGAAGTCTATGACATTATCATACTTACAGAAAATTCTTGGCCTGGATTCCTTAGAAGAAGTTTTAGACGTCAAACT TGTCAATTCGAAGTTCATCATCCATAATGTATATAGTGTTAGCAAGCAGGGAGTTGTTATTCTTGATGACAAGTCAAAAGAACTTCCTCA TTGGGTGCTGTCAGCTATGAAGTGTTTGGCAAATTGGCCCAACTGTTCTGATTTGAAGCAGCCTATGTACTTGGGATTTGAAAAAGATGT CTTTAAAACCATAGCTGATTACTATGGTCACTTGAAAGAGCCTCTACTTACATTTCATCTTTTTGATGCTTTTGTCAGTGTACTGGGTTT GTTACAGAAGGAGAAAGTGGCAGTTGAAGCATTTCAGATTTGCTGCCTTCTCCTACCTCCTGAAAATAGGAGAAAGTTACAGCTATTGAT GAGGATGATGGCAAGGATTTGCTTAAACAAAGAGATGCCACCCCTGTGTGATGGCTTTGGTACCCGAACACTGATGGTTCAGACATTTTC CCGTTGCATCTTGTGTTCCAAGGATGAAGTGGACTTGGATGAGTTATTAGCTGCTAGATTGGTAACGTTTCTGATGGACAATTACCAGGA AATTCTGAAAGTCCCTTTGGCCTTGCAGACCTCTATAGAGGAGCGTGTGGCTCATCTACGAAGAGTCCAGATAAAATACCCAGGAGCTGA TATGGATATCACTTTATCTGCTCCATCATTTTGCCGTCAAATTAGTCCAGAGGAATTTGAATATCAAAGATCATATGGCTCTCAGGAACC TCTGGCAGCCTTGTTGGAGGAAGTCATAACAGATGCCAAACTCTCCAACAAAGAGAAAAAGAAGAAACTGAAGCAGTTTCAGAAATCCTA TCCTGAAGTCTATCAAGAACGATTTCCTACACCAGAAAGTGCAGCACTTCTGTTTCCTGAAAAACCCAAACCGAAACCACAGCTGCTAAT >In-frame_PDE4D_ENST00000502484_chr5_59481384_-_DEPDC1B_ENST00000453022_chr5_59943360_-_1132nt ATGAAAAGAAATACCTGTGATTTGCTTTCTCGGAGCAAAAGTATTTCCTCCTTCTTCACCCCTGAAACCATATCCAAAGAAGCCCCCAAA CCAAAAGGATGTTATTAAATTTCCAGAATGGAATGATCTCCCACCAGGCACTTCACAAGAGAACATCCCAGTGAGGCCAGTTGTGATGAA TTCTGAGATGTGGTACAAGCGTCACAGTATTGCAATTGGAGAGGTGCCAGCTTGCCGTCTTGTCCACCGCAGACAGCTGACAGAGGCCAA TGTAGAAGAGATATGGAAGTCTATGACATTATCATACTTACAGAAAATTCTTGGCCTGGATTCCTTAGAAGAAGTTTTAGACGTCAAACT TGTCAATTCGAAGTTCATCATCCATAATGTATATAGTGTTAGCAAGCAGGGAGTTGTTATTCTTGATGACAAGTCAAAAGAACTTCCTCA TTGGGTGCTGTCAGCTATGAAGTGTTTGGCAAATTGGCCCAACTGTTCTGATTTGAAGCAGCCTATGTACTTGGGATTTGAAAAAGATGT CTTTAAAACCATAGCTGATTACTATGGTCACTTGAAAGAGCCTCTACTTACATTTCATCTTTTTGATGCTTTTGTCAGTGTACTGGGTTT GTTACAGAAGGAGAAAGTGGCAGTTGAAGCATTTCAGATTTGCTGCCTTCTCCTACCTCCTGAAAATAGGAGAAAGTTACAGCTATTGAT GAGGATGATGGCAAGGATTTGCTTAAACAAAGAGATGCCACCCCTGTGTGATGGCTTTGGTACCCGAACACTGATGGTTCAGACATTTTC CCGTTGCATCTTGTGTTCCAAGGATGAAGTGGACTTGGATGAGTTATTAGCTGCTAGATTGGTAACGTTTCTGATGGACAATTACCAGGA AATTCTGAAAGTCCCTTTGGCCTTGCAGACCTCTATAGAGGAGCGTGTGGCTCATCTACGAAGAGTCCAGTTTCAGAAATCCTATCCTGA AGTCTATCAAGAACGATTTCCTACACCAGAAAGTGCAGCACTTCTGTTTCCTGAAAAACCCAAACCGAAACCACAGCTGCTAATGTGGGC >In-frame_PDE4D_ENST00000502484_chr5_59481384_-_DEPDC1B_ENST00000545085_chr5_59943360_-_1132nt ATGAAAAGAAATACCTGTGATTTGCTTTCTCGGAGCAAAAGTATTTCCTCCTTCTTCACCCCTGAAACCATATCCAAAGAAGCCCCCAAA CCAAAAGGATGTTATTAAATTTCCAGAATGGAATGATCTCCCACCAGGCACTTCACAAGAGAACATCCCAGTGAGGCCAGTTGTGATGAA TTCTGAGATGTGGTACAAGCGTCACAGTATTGCAATTGGAGAGGTGCCAGCTTGCCGTCTTGTCCACCGCAGACAGCTGACAGAGGCCAA TGTAGAAGAGATATGGAAGTCTATGACATTATCATACTTACAGAAAATTCTTGGCCTGGATTCCTTAGAAGAAGTTTTAGACGTCAAACT TGTCAATTCGAAGTTCATCATCCATAATGTATATAGTGTTAGCAAGCAGGGAGTTGTTATTCTTGATGACAAGTCAAAAGAACTTCCTCA TTGGGTGCTGTCAGCTATGAAGTGTTTGGCAAATTGGCCCAACTGTTCTGATTTGAAGCAGCCTATGTACTTGGGATTTGAAAAAGATGT CTTTAAAACCATAGCTGATTACTATGGTCACTTGAAAGAGCCTCTACTTACATTTCATCTTTTTGATGCTTTTGTCAGTGTACTGGGTTT GTTACAGAAGGAGAAAGTGGCAGTTGAAGCATTTCAGATTTGCTGCCTTCTCCTACCTCCTGAAAATAGGAGAAAGTTACAGCTATTGAT GAGGATGATGGCAAGGATTTGCTTAAACAAAGAGATGCCACCCCTGTGTGATGGCTTTGGTACCCGAACACTGATGGTTCAGACATTTTC CCGTTGCATCTTGTGTTCCAAGGATGAAGTGGACTTGGATGAGTTATTAGCTGCTAGATTGGTAACGTTTCTGATGGACAATTACCAGGA AATTCTGAAAGTCCCTTTGGCCTTGCAGACCTCTATAGAGGAGCGTGTGGCTCATCTACGAAGAGTCCAGTTTCAGAAATCCTATCCTGA AGTCTATCAAGAACGATTTCCTACACCAGAAAGTGCAGCACTTCTGTTTCCTGAAAAACCCAAACCGAAACCACAGCTGCTAATGTGGGC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_PDE4D_ENST00000546160_chr5_59481384_-_DEPDC1B_ENST00000265036_chr5_59983054_-_2425nt ATGAAAAGAAATACCTGTGATTTGCTTTCTCGGAGCAAAAGTTGGAATGAGACCGTGGAGCTTTTTCGTGCTAAGATGCCGTTACGGAAA CATCGCTGTCGTTTCAAGAGCTATGAGCATTGTTTCACAGCGGCCGAAGCTGTGGATTGGCTGCATGAGCTGCTGAGGTGCAGTCAAAAC TTCGGCCCTGAAGTGACCCGCAAACAAACGGTCCAGCTGCTAAAAAAATTCCTGAAGAATCACGTTATTGAAGACATCAAGGGAAAATGG GGTGAGGAAGATTTTGAAGACAATCGTCACTTATACAGATTTCCTCCTTCTTCACCCCTGAAACCATATCCAAAGAAGCCCCCAAACCAA AAGGATGTTATTAAATTTCCAGAATGGAATGATCTCCCACCAGGCACTTCACAAGAGAACATCCCAGTGAGGCCAGTTGTGATGAATTCT GAGATGTGGTACAAGCGTCACAGTATTGCAATTGGAGAGGTGCCAGCTTGCCGTCTTGTCCACCGCAGACAGCTGACAGAGGCCAATGTA GAAGAGATATGGAAGTCTATGACATTATCATACTTACAGAAAATTCTTGGCCTGGATTCCTTAGAAGAAGTTTTAGACGTCAAACTTGTC AATTCGAAGTTCATCATCCATAATGTATATAGTGTTAGCAAGCAGGGAGTTGTTATTCTTGATGACAAGTCAAAAGAACTTCCTCATTGG GTGCTGTCAGCTATGAAGTGTTTGGCAAATTGGCCCAACTGTTCTGATTTGAAGCAGCCTATGTACTTGGGATTTGAAAAAGATGTCTTT AAAACCATAGCTGATTACTATGGTCACTTGAAAGAGCCTCTACTTACATTTCATCTTTTTGATGCTTTTGTCAGTGTACTGGGTTTGTTA CAGAAGGAGAAAGTGGCAGTTGAAGCATTTCAGATTTGCTGCCTTCTCCTACCTCCTGAAAATAGGAGAAAGTTACAGCTATTGATGAGG ATGATGGCAAGGATTTGCTTAAACAAAGAGATGCCACCCCTGTGTGATGGCTTTGGTACCCGAACACTGATGGTTCAGACATTTTCCCGT TGCATCTTGTGTTCCAAGGATGAAGTGGACTTGGATGAGTTATTAGCTGCTAGATTGGTAACGTTTCTGATGGACAATTACCAGGAAATT CTGAAAGTCCCTTTGGCCTTGCAGACCTCTATAGAGGAGCGTGTGGCTCATCTACGAAGAGTCCAGATAAAATACCCAGGAGCTGATATG GATATCACTTTATCTGCTCCATCATTTTGCCGTCAAATTAGTCCAGAGGAATTTGAATATCAAAGATCATATGGCTCTCAGGAACCTCTG GCAGCCTTGTTGGAGGAAGTCATAACAGATGCCAAACTCTCCAACAAAGAGAAAAAGAAGAAACTGAAGCAGTTTCAGAAATCCTATCCT GAAGTCTATCAAGAACGATTTCCTACACCAGAAAGTGCAGCACTTCTGTTTCCTGAAAAACCCAAACCGAAACCACAGCTGCTAATGTGG GCACTAAAGAAGCCTTTCCAACCATTTCAAAGAACTAGAAGTTTTCGAATGTAATAATACTTCCACAGCAACAGGTGCTAGAGACCACTG TTGTTGTTTTGAGTGAATGGTGGTTAGGAGAAAGACTTTGGTGGTGGAAGAAAGAAAAGCATAAAACAAAGACTACTGAAATATAGATAA AGATTGCCTTAGTTTTTAAAAATGTTTGGCCATTAGTATTTTTATAAAACTCAATGCTAGTTTTAAAGTGTATAAATTGGTTAAAATTTA TGAGTCAAATATATAGTGATAATGTTAACATGTTTGTAATTGCTACAGAATTTAAGGGTATTTTTATCTCTGTGCTTTCTTTTTCATGGT GTTTATTAAATAATTGTGTATATACATCCTAGCTACTGATATCTTTATTATAGCCTTAAGACTTAATTTTAAGTCTTAAAAATAGCGTGT ATACTTGAATAAGAAAGACACTGGGTACTGTTACTGTGATGCTATTGACTTAGTAGCCAATTATCATTTCTCCTGTATAAATTCCAGTTT TTATTGCTGCACATAAATTTTTTAATGTCTTATATTGTGATAGCTATGTCTTTTATTGCAGATTTATTGGATGTTATGACAGATTTTACT AAAGCTAGTGTTTTTATAACATATATATTAGTTGATGTTTACCTATAAGTGGAGTAGATTTTCATCTGCCTGCAATGGTATAATTTCAGT CTTAGCTAAAAATGGAAAGTTGAACTGGATAAATTCTTTGGGTACCCTTAGACCTCTGATTCTAAGTCAAATGCAAATGGGTTAAATAAA >In-frame_PDE4D_ENST00000546160_chr5_59481384_-_DEPDC1B_ENST00000453022_chr5_59983054_-_1522nt ATGAAAAGAAATACCTGTGATTTGCTTTCTCGGAGCAAAAGTTGGAATGAGACCGTGGAGCTTTTTCGTGCTAAGATGCCGTTACGGAAA CATCGCTGTCGTTTCAAGAGCTATGAGCATTGTTTCACAGCGGCCGAAGCTGTGGATTGGCTGCATGAGCTGCTGAGGTGCAGTCAAAAC TTCGGCCCTGAAGTGACCCGCAAACAAACGGTCCAGCTGCTAAAAAAATTCCTGAAGAATCACGTTATTGAAGACATCAAGGGAAAATGG GGTGAGGAAGATTTTGAAGACAATCGTCACTTATACAGATTTCCTCCTTCTTCACCCCTGAAACCATATCCAAAGAAGCCCCCAAACCAA AAGGATGTTATTAAATTTCCAGAATGGAATGATCTCCCACCAGGCACTTCACAAGAGAACATCCCAGTGAGGCCAGTTGTGATGAATTCT GAGATGTGGTACAAGCGTCACAGTATTGCAATTGGAGAGGTGCCAGCTTGCCGTCTTGTCCACCGCAGACAGCTGACAGAGGCCAATGTA GAAGAGATATGGAAGTCTATGACATTATCATACTTACAGAAAATTCTTGGCCTGGATTCCTTAGAAGAAGTTTTAGACGTCAAACTTGTC AATTCGAAGTTCATCATCCATAATGTATATAGTGTTAGCAAGCAGGGAGTTGTTATTCTTGATGACAAGTCAAAAGAACTTCCTCATTGG GTGCTGTCAGCTATGAAGTGTTTGGCAAATTGGCCCAACTGTTCTGATTTGAAGCAGCCTATGTACTTGGGATTTGAAAAAGATGTCTTT AAAACCATAGCTGATTACTATGGTCACTTGAAAGAGCCTCTACTTACATTTCATCTTTTTGATGCTTTTGTCAGTGTACTGGGTTTGTTA CAGAAGGAGAAAGTGGCAGTTGAAGCATTTCAGATTTGCTGCCTTCTCCTACCTCCTGAAAATAGGAGAAAGTTACAGCTATTGATGAGG ATGATGGCAAGGATTTGCTTAAACAAAGAGATGCCACCCCTGTGTGATGGCTTTGGTACCCGAACACTGATGGTTCAGACATTTTCCCGT TGCATCTTGTGTTCCAAGGATGAAGTGGACTTGGATGAGTTATTAGCTGCTAGATTGGTAACGTTTCTGATGGACAATTACCAGGAAATT CTGAAAGTCCCTTTGGCCTTGCAGACCTCTATAGAGGAGCGTGTGGCTCATCTACGAAGAGTCCAGTTTCAGAAATCCTATCCTGAAGTC TATCAAGAACGATTTCCTACACCAGAAAGTGCAGCACTTCTGTTTCCTGAAAAACCCAAACCGAAACCACAGCTGCTAATGTGGGCACTA AAGAAGCCTTTCCAACCATTTCAAAGAACTAGAAGTTTTCGAATGTAATAATACTTCCACAGCAACAGGTGCTAGAGACCACTGTTGTTG >In-frame_PDE4D_ENST00000502484_chr5_59481384_-_DEPDC1B_ENST00000265036_chr5_59943360_-_2383nt AAGCACGAGTCCTATAGTTGGCGTACCCTGAGGCCTGCCAGTTCCTGCCTTAATGCATATGTAGTCGTAATTGAGTTCTGACACGGCCTT GGATGTTTCTGTCCTAAATAGCTGACATTGCATCTTCAAGACTGTCATTCCAGTTGGCTTTTGAGTGGATACGTGCAGTGAGATCATTGA CACTGGAAACACTAGTTCCCATTTTAATTACTTAAAACACCACGATGAAAAGAAATACCTGTGATTTGCTTTCTCGGAGCAAAAGTATTT CCTCCTTCTTCACCCCTGAAACCATATCCAAAGAAGCCCCCAAACCAAAAGGATGTTATTAAATTTCCAGAATGGAATGATCTCCCACCA GGCACTTCACAAGAGAACATCCCAGTGAGGCCAGTTGTGATGAATTCTGAGATGTGGTACAAGCGTCACAGTATTGCAATTGGAGAGGTG CCAGCTTGCCGTCTTGTCCACCGCAGACAGCTGACAGAGGCCAATGTAGAAGAGATATGGAAGTCTATGACATTATCATACTTACAGAAA ATTCTTGGCCTGGATTCCTTAGAAGAAGTTTTAGACGTCAAACTTGTCAATTCGAAGTTCATCATCCATAATGTATATAGTGTTAGCAAG CAGGGAGTTGTTATTCTTGATGACAAGTCAAAAGAACTTCCTCATTGGGTGCTGTCAGCTATGAAGTGTTTGGCAAATTGGCCCAACTGT TCTGATTTGAAGCAGCCTATGTACTTGGGATTTGAAAAAGATGTCTTTAAAACCATAGCTGATTACTATGGTCACTTGAAAGAGCCTCTA CTTACATTTCATCTTTTTGATGCTTTTGTCAGTGTACTGGGTTTGTTACAGAAGGAGAAAGTGGCAGTTGAAGCATTTCAGATTTGCTGC CTTCTCCTACCTCCTGAAAATAGGAGAAAGTTACAGCTATTGATGAGGATGATGGCAAGGATTTGCTTAAACAAAGAGATGCCACCCCTG TGTGATGGCTTTGGTACCCGAACACTGATGGTTCAGACATTTTCCCGTTGCATCTTGTGTTCCAAGGATGAAGTGGACTTGGATGAGTTA TTAGCTGCTAGATTGGTAACGTTTCTGATGGACAATTACCAGGAAATTCTGAAAGTCCCTTTGGCCTTGCAGACCTCTATAGAGGAGCGT GTGGCTCATCTACGAAGAGTCCAGATAAAATACCCAGGAGCTGATATGGATATCACTTTATCTGCTCCATCATTTTGCCGTCAAATTAGT CCAGAGGAATTTGAATATCAAAGATCATATGGCTCTCAGGAACCTCTGGCAGCCTTGTTGGAGGAAGTCATAACAGATGCCAAACTCTCC AACAAAGAGAAAAAGAAGAAACTGAAGCAGTTTCAGAAATCCTATCCTGAAGTCTATCAAGAACGATTTCCTACACCAGAAAGTGCAGCA CTTCTGTTTCCTGAAAAACCCAAACCGAAACCACAGCTGCTAATGTGGGCACTAAAGAAGCCTTTCCAACCATTTCAAAGAACTAGAAGT TTTCGAATGTAATAATACTTCCACAGCAACAGGTGCTAGAGACCACTGTTGTTGTTTTGAGTGAATGGTGGTTAGGAGAAAGACTTTGGT GGTGGAAGAAAGAAAAGCATAAAACAAAGACTACTGAAATATAGATAAAGATTGCCTTAGTTTTTAAAAATGTTTGGCCATTAGTATTTT TATAAAACTCAATGCTAGTTTTAAAGTGTATAAATTGGTTAAAATTTATGAGTCAAATATATAGTGATAATGTTAACATGTTTGTAATTG CTACAGAATTTAAGGGTATTTTTATCTCTGTGCTTTCTTTTTCATGGTGTTTATTAAATAATTGTGTATATACATCCTAGCTACTGATAT CTTTATTATAGCCTTAAGACTTAATTTTAAGTCTTAAAAATAGCGTGTATACTTGAATAAGAAAGACACTGGGTACTGTTACTGTGATGC TATTGACTTAGTAGCCAATTATCATTTCTCCTGTATAAATTCCAGTTTTTATTGCTGCACATAAATTTTTTAATGTCTTATATTGTGATA GCTATGTCTTTTATTGCAGATTTATTGGATGTTATGACAGATTTTACTAAAGCTAGTGTTTTTATAACATATATATTAGTTGATGTTTAC CTATAAGTGGAGTAGATTTTCATCTGCCTGCAATGGTATAATTTCAGTCTTAGCTAAAAATGGAAAGTTGAACTGGATAAATTCTTTGGG TACCCTTAGACCTCTGATTCTAAGTCAAATGCAAATGGGTTAAATAAAATGAGACTACTTCCTTTATAAATATATTTTCATCCTTTTGAA >In-frame_PDE4D_ENST00000502484_chr5_59481384_-_DEPDC1B_ENST00000453022_chr5_59943360_-_1480nt AAGCACGAGTCCTATAGTTGGCGTACCCTGAGGCCTGCCAGTTCCTGCCTTAATGCATATGTAGTCGTAATTGAGTTCTGACACGGCCTT GGATGTTTCTGTCCTAAATAGCTGACATTGCATCTTCAAGACTGTCATTCCAGTTGGCTTTTGAGTGGATACGTGCAGTGAGATCATTGA CACTGGAAACACTAGTTCCCATTTTAATTACTTAAAACACCACGATGAAAAGAAATACCTGTGATTTGCTTTCTCGGAGCAAAAGTATTT CCTCCTTCTTCACCCCTGAAACCATATCCAAAGAAGCCCCCAAACCAAAAGGATGTTATTAAATTTCCAGAATGGAATGATCTCCCACCA GGCACTTCACAAGAGAACATCCCAGTGAGGCCAGTTGTGATGAATTCTGAGATGTGGTACAAGCGTCACAGTATTGCAATTGGAGAGGTG CCAGCTTGCCGTCTTGTCCACCGCAGACAGCTGACAGAGGCCAATGTAGAAGAGATATGGAAGTCTATGACATTATCATACTTACAGAAA ATTCTTGGCCTGGATTCCTTAGAAGAAGTTTTAGACGTCAAACTTGTCAATTCGAAGTTCATCATCCATAATGTATATAGTGTTAGCAAG CAGGGAGTTGTTATTCTTGATGACAAGTCAAAAGAACTTCCTCATTGGGTGCTGTCAGCTATGAAGTGTTTGGCAAATTGGCCCAACTGT TCTGATTTGAAGCAGCCTATGTACTTGGGATTTGAAAAAGATGTCTTTAAAACCATAGCTGATTACTATGGTCACTTGAAAGAGCCTCTA CTTACATTTCATCTTTTTGATGCTTTTGTCAGTGTACTGGGTTTGTTACAGAAGGAGAAAGTGGCAGTTGAAGCATTTCAGATTTGCTGC CTTCTCCTACCTCCTGAAAATAGGAGAAAGTTACAGCTATTGATGAGGATGATGGCAAGGATTTGCTTAAACAAAGAGATGCCACCCCTG TGTGATGGCTTTGGTACCCGAACACTGATGGTTCAGACATTTTCCCGTTGCATCTTGTGTTCCAAGGATGAAGTGGACTTGGATGAGTTA TTAGCTGCTAGATTGGTAACGTTTCTGATGGACAATTACCAGGAAATTCTGAAAGTCCCTTTGGCCTTGCAGACCTCTATAGAGGAGCGT GTGGCTCATCTACGAAGAGTCCAGTTTCAGAAATCCTATCCTGAAGTCTATCAAGAACGATTTCCTACACCAGAAAGTGCAGCACTTCTG TTTCCTGAAAAACCCAAACCGAAACCACAGCTGCTAATGTGGGCACTAAAGAAGCCTTTCCAACCATTTCAAAGAACTAGAAGTTTTCGA ATGTAATAATACTTCCACAGCAACAGGTGCTAGAGACCACTGTTGTTGTTTTGAGTGAATGGTGGTTAGGAGAAAGACTTTGGTGGTGGA >In-frame_PDE4D_ENST00000502484_chr5_59481384_-_DEPDC1B_ENST00000545085_chr5_59943360_-_1441nt AAGCACGAGTCCTATAGTTGGCGTACCCTGAGGCCTGCCAGTTCCTGCCTTAATGCATATGTAGTCGTAATTGAGTTCTGACACGGCCTT GGATGTTTCTGTCCTAAATAGCTGACATTGCATCTTCAAGACTGTCATTCCAGTTGGCTTTTGAGTGGATACGTGCAGTGAGATCATTGA CACTGGAAACACTAGTTCCCATTTTAATTACTTAAAACACCACGATGAAAAGAAATACCTGTGATTTGCTTTCTCGGAGCAAAAGTATTT CCTCCTTCTTCACCCCTGAAACCATATCCAAAGAAGCCCCCAAACCAAAAGGATGTTATTAAATTTCCAGAATGGAATGATCTCCCACCA GGCACTTCACAAGAGAACATCCCAGTGAGGCCAGTTGTGATGAATTCTGAGATGTGGTACAAGCGTCACAGTATTGCAATTGGAGAGGTG CCAGCTTGCCGTCTTGTCCACCGCAGACAGCTGACAGAGGCCAATGTAGAAGAGATATGGAAGTCTATGACATTATCATACTTACAGAAA ATTCTTGGCCTGGATTCCTTAGAAGAAGTTTTAGACGTCAAACTTGTCAATTCGAAGTTCATCATCCATAATGTATATAGTGTTAGCAAG CAGGGAGTTGTTATTCTTGATGACAAGTCAAAAGAACTTCCTCATTGGGTGCTGTCAGCTATGAAGTGTTTGGCAAATTGGCCCAACTGT TCTGATTTGAAGCAGCCTATGTACTTGGGATTTGAAAAAGATGTCTTTAAAACCATAGCTGATTACTATGGTCACTTGAAAGAGCCTCTA CTTACATTTCATCTTTTTGATGCTTTTGTCAGTGTACTGGGTTTGTTACAGAAGGAGAAAGTGGCAGTTGAAGCATTTCAGATTTGCTGC CTTCTCCTACCTCCTGAAAATAGGAGAAAGTTACAGCTATTGATGAGGATGATGGCAAGGATTTGCTTAAACAAAGAGATGCCACCCCTG TGTGATGGCTTTGGTACCCGAACACTGATGGTTCAGACATTTTCCCGTTGCATCTTGTGTTCCAAGGATGAAGTGGACTTGGATGAGTTA TTAGCTGCTAGATTGGTAACGTTTCTGATGGACAATTACCAGGAAATTCTGAAAGTCCCTTTGGCCTTGCAGACCTCTATAGAGGAGCGT GTGGCTCATCTACGAAGAGTCCAGTTTCAGAAATCCTATCCTGAAGTCTATCAAGAACGATTTCCTACACCAGAAAGTGCAGCACTTCTG TTTCCTGAAAAACCCAAACCGAAACCACAGCTGCTAATGTGGGCACTAAAGAAGCCTTTCCAACCATTTCAAAGAACTAGAAGTTTTCGA ATGTAATAATACTTCCACAGCAACAGGTGCTAGAGACCACTGTTGTTGTTTTGAGTGAATGGTGGTTAGGAGAAAGACTTTGGTGGTGGA |
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FusionGenePPI for PDE4D_DEPDC1B |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| PDE4D | PDE4DIP, PDE4D, AKAP6, GNB2L1, ARRB1, MDM2, ITSN1, ARRB2, PPP3CA, PPP3CB, PPP3R1, GSK3B, CSNK1A1, CDK2, PAFAH1B1, PRKACA, APP, LYN, SRC, FYN, ABL1, GRB2, PIAS4, MAPK1, BIN1, HDGFRP2, ZBTB1, MAGEA6, TRAF1, COIL, GOLGA8EP, GOLGA8F, ZDHHC17, SPTAN1, PIK3R1, TRIM23, ITPKB, PFKFB2, AKAP12, ATOH1, DUSP13, PDE4B, TRIM25 | DEPDC1B | MDC1, EBPL, IFI30, TCTN2, TCTN3, CETN2, TMEM17, KCTD3, KIF13B, ZBTB21, KSR1, GIGYF1, LRFN1, DENND1A, SH3PXD2A, SRGAP2, EIF4E2, SIPA1L1, LIMA1, MAGI1, TESK2, DCLK1, ZNF638, SRSF12, SYDE1, AGAP1, CDC25B, CDK16, PPM1H, MAST3, RTKN, FAM110B, USP21, FAM53C, ANKRD34A, FAM110A, CBY1, RAB3IP |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for PDE4D_DEPDC1B |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Hgene | PDE4D | Q08499 | DB00651 | Dyphylline | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | small molecule | approved |
| Hgene | PDE4D | Q08499 | DB01656 | Roflumilast | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | small molecule | approved |
| Hgene | PDE4D | Q08499 | DB01088 | Iloprost | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | small molecule | approved|investigational |
| Hgene | PDE4D | Q08499 | DB05266 | Ibudilast | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | small molecule | approved|investigational |
| Hgene | PDE4D | Q08499 | DB05676 | Apremilast | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | small molecule | approved|investigational |
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RelatedDiseases for PDE4D_DEPDC1B |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | PDE4D | C3553250 | ACRODYSOSTOSIS 2 WITH OR WITHOUT HORMONE RESISTANCE | 4 | UNIPROT |
| Hgene | PDE4D | C0011581 | Depressive disorder | 3 | PSYGENET |
| Hgene | PDE4D | C0004096 | Asthma | 2 | CTD_human |
| Hgene | PDE4D | C0011570 | Mental Depression | 2 | PSYGENET |
| Hgene | PDE4D | C0033578 | Prostatic Neoplasms | 1 | CTD_human |
| Hgene | PDE4D | C0036341 | Schizophrenia | 1 | PSYGENET |
| Hgene | PDE4D | C0236733 | Amphetamine-Related Disorders | 1 | CTD_human |
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