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Fusion gene ID: 26234 |
FusionGeneSummary for PCID2_SNRPA |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PCID2_SNRPA | Fusion gene ID: 26234 | Hgene | Tgene | Gene symbol | PCID2 | SNRPA | Gene ID | 55795 | 6626 |
| Gene name | PCI domain containing 2 | small nuclear ribonucleoprotein polypeptide A | |
| Synonyms | F10 | Mud1|U1-A|U1A | |
| Cytomap | 13q34 | 19q13.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | PCI domain-containing protein 2CSN12-like protein | U1 small nuclear ribonucleoprotein AU1 small nuclear RNP-specific AU1 snRNP AU1 snRNP-specific protein A | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q5JVF3 | P09012 | |
| Ensembl transtripts involved in fusion gene | ENST00000337344, ENST00000375477, ENST00000375479, ENST00000493650, ENST00000375459, ENST00000246505, ENST00000375457, | ENST00000243563, ENST00000599570, | |
| Fusion gene scores | * DoF score | 5 X 3 X 4=60 | 2 X 2 X 2=8 |
| # samples | 4 | 2 | |
| ** MAII score | log2(4/60*10)=-0.584962500721156 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: PCID2 [Title/Abstract] AND SNRPA [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LGG | TCGA-E1-A7Z2-01A | PCID2 | chr13 | 113862913 | - | SNRPA | chr19 | 41265336 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000337344 | ENST00000243563 | PCID2 | chr13 | 113862913 | - | SNRPA | chr19 | 41265336 | + |
| 5CDS-3UTR | ENST00000337344 | ENST00000599570 | PCID2 | chr13 | 113862913 | - | SNRPA | chr19 | 41265336 | + |
| In-frame | ENST00000375477 | ENST00000243563 | PCID2 | chr13 | 113862913 | - | SNRPA | chr19 | 41265336 | + |
| 5CDS-3UTR | ENST00000375477 | ENST00000599570 | PCID2 | chr13 | 113862913 | - | SNRPA | chr19 | 41265336 | + |
| In-frame | ENST00000375479 | ENST00000243563 | PCID2 | chr13 | 113862913 | - | SNRPA | chr19 | 41265336 | + |
| 5CDS-3UTR | ENST00000375479 | ENST00000599570 | PCID2 | chr13 | 113862913 | - | SNRPA | chr19 | 41265336 | + |
| intron-3CDS | ENST00000493650 | ENST00000243563 | PCID2 | chr13 | 113862913 | - | SNRPA | chr19 | 41265336 | + |
| intron-3UTR | ENST00000493650 | ENST00000599570 | PCID2 | chr13 | 113862913 | - | SNRPA | chr19 | 41265336 | + |
| intron-3CDS | ENST00000375459 | ENST00000243563 | PCID2 | chr13 | 113862913 | - | SNRPA | chr19 | 41265336 | + |
| intron-3UTR | ENST00000375459 | ENST00000599570 | PCID2 | chr13 | 113862913 | - | SNRPA | chr19 | 41265336 | + |
| In-frame | ENST00000246505 | ENST00000243563 | PCID2 | chr13 | 113862913 | - | SNRPA | chr19 | 41265336 | + |
| 5CDS-3UTR | ENST00000246505 | ENST00000599570 | PCID2 | chr13 | 113862913 | - | SNRPA | chr19 | 41265336 | + |
| intron-3CDS | ENST00000375457 | ENST00000243563 | PCID2 | chr13 | 113862913 | - | SNRPA | chr19 | 41265336 | + |
| intron-3UTR | ENST00000375457 | ENST00000599570 | PCID2 | chr13 | 113862913 | - | SNRPA | chr19 | 41265336 | + |
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FusionProtFeatures for PCID2_SNRPA |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| PCID2 | SNRPA |
| Component of the spliceosomal U1 snRNP, which isessential for recognition of the pre-mRNA 5' splice-site and thesubsequent assembly of the spliceosome. U1 snRNP is the firstsnRNP to interact with pre-mRNA. This interaction is required forthe subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP.SNRPA binds stem loop II of U1 snRNA. In a snRNP-free form (SF-A)may be involved in coupled pre-mRNA splicing and polyadenylationprocess. May bind preferentially to the 5'-UGCAC-3' motif on RNAs.{ECO:0000269|PubMed:9848648}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >SNRPA | chr13:113862913 | chr19:41265336 | ENST00000243563 | + | 1 | 6 | 140_206 | 82 | 283 | Compositional bias | Note=Pro-rich |
| Tgene | >SNRPA | chr13:113862913 | chr19:41265336 | ENST00000243563 | + | 1 | 6 | 208_282 | 82 | 283 | Domain | RRM 2 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >PCID2 | chr13:113862913 | chr19:41265336 | ENST00000246505 | - | 1 | 15 | 210_391 | 12 | 560 | Domain | PCI |
| Hgene | >PCID2 | chr13:113862913 | chr19:41265336 | ENST00000337344 | - | 1 | 14 | 210_391 | 12 | 400 | Domain | PCI |
| Hgene | >PCID2 | chr13:113862913 | chr19:41265336 | ENST00000375457 | - | 1 | 14 | 210_391 | -199 | 398 | Domain | PCI |
| Hgene | >PCID2 | chr13:113862913 | chr19:41265336 | ENST00000375459 | - | 1 | 15 | 210_391 | -18 | 510 | Domain | PCI |
| Hgene | >PCID2 | chr13:113862913 | chr19:41265336 | ENST00000375477 | - | 1 | 15 | 210_391 | 12 | 518 | Domain | PCI |
| Hgene | >PCID2 | chr13:113862913 | chr19:41265336 | ENST00000375479 | - | 1 | 15 | 210_391 | 12 | 491 | Domain | PCI |
| Tgene | SNRPA | chr13:113862913 | chr19:41265336 | ENST00000243563 | + | 1 | 6 | 10_89 | 82 | 283 | Domain | RRM 1 |
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FusionGeneSequence for PCID2_SNRPA |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_PCID2_ENST00000337344_chr13_113862913_-_SNRPA_ENST00000243563_chr19_41265336_+_213aa MAHITINQYLQQRIQYAKTDSDIIAKMKGTFVERDRKREKRKPKSQETPATKKAVQGGGATPVVGAVQGPVPGMPPMTQAPRIMHHMPGQ PPYMPPPGMIPPPGLAPGQIPPGAMPPQQLMPGQMPPAQPLSENPPNHILFLTNLPEETNELMLSMLFNQFPGFKEVRLVPGRHDIAFVE >In-frame_PCID2_ENST00000375477_chr13_113862913_-_SNRPA_ENST00000243563_chr19_41265336_+_213aa MAHITINQYLQQRIQYAKTDSDIIAKMKGTFVERDRKREKRKPKSQETPATKKAVQGGGATPVVGAVQGPVPGMPPMTQAPRIMHHMPGQ PPYMPPPGMIPPPGLAPGQIPPGAMPPQQLMPGQMPPAQPLSENPPNHILFLTNLPEETNELMLSMLFNQFPGFKEVRLVPGRHDIAFVE >In-frame_PCID2_ENST00000375479_chr13_113862913_-_SNRPA_ENST00000243563_chr19_41265336_+_213aa MAHITINQYLQQRIQYAKTDSDIIAKMKGTFVERDRKREKRKPKSQETPATKKAVQGGGATPVVGAVQGPVPGMPPMTQAPRIMHHMPGQ PPYMPPPGMIPPPGLAPGQIPPGAMPPQQLMPGQMPPAQPLSENPPNHILFLTNLPEETNELMLSMLFNQFPGFKEVRLVPGRHDIAFVE >In-frame_PCID2_ENST00000246505_chr13_113862913_-_SNRPA_ENST00000243563_chr19_41265336_+_213aa MAHITINQYLQQRIQYAKTDSDIIAKMKGTFVERDRKREKRKPKSQETPATKKAVQGGGATPVVGAVQGPVPGMPPMTQAPRIMHHMPGQ PPYMPPPGMIPPPGLAPGQIPPGAMPPQQLMPGQMPPAQPLSENPPNHILFLTNLPEETNELMLSMLFNQFPGFKEVRLVPGRHDIAFVE |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_PCID2_ENST00000337344_chr13_113862913_-_SNRPA_ENST00000243563_chr19_41265336_+_639nt ATGGCGCACATTACCATTAACCAGTACCTGCAGCAGCGTATCCAGTATGCCAAGACCGACTCAGATATCATTGCCAAGATGAAAGGCACC TTCGTGGAGCGGGACCGCAAGCGGGAGAAGAGGAAGCCCAAGAGCCAGGAGACCCCGGCCACCAAGAAGGCTGTGCAAGGCGGGGGAGCC ACCCCCGTGGTGGGGGCTGTCCAGGGGCCTGTCCCGGGCATGCCGCCGATGACTCAGGCGCCCCGCATTATGCACCACATGCCGGGCCAG CCGCCCTACATGCCGCCCCCTGGTATGATCCCCCCGCCAGGCCTTGCACCTGGCCAGATCCCACCAGGGGCCATGCCCCCGCAGCAGCTT ATGCCAGGACAGATGCCCCCTGCCCAGCCTCTTTCTGAGAATCCACCGAATCACATCTTGTTCCTCACCAACCTGCCAGAGGAGACCAAC GAGCTCATGCTGTCCATGCTTTTCAATCAGTTCCCTGGCTTCAAGGAGGTCCGTCTGGTACCCGGGCGGCATGACATCGCCTTCGTGGAG TTTGACAATGAGGTACAGGCAGGGGCAGCTCGCGATGCCCTGCAGGGCTTTAAGATCACGCAGAACAACGCCATGAAGATCTCCTTTGCC >In-frame_PCID2_ENST00000375477_chr13_113862913_-_SNRPA_ENST00000243563_chr19_41265336_+_639nt ATGGCGCACATTACCATTAACCAGTACCTGCAGCAGCGTATCCAGTATGCCAAGACCGACTCAGATATCATTGCCAAGATGAAAGGCACC TTCGTGGAGCGGGACCGCAAGCGGGAGAAGAGGAAGCCCAAGAGCCAGGAGACCCCGGCCACCAAGAAGGCTGTGCAAGGCGGGGGAGCC ACCCCCGTGGTGGGGGCTGTCCAGGGGCCTGTCCCGGGCATGCCGCCGATGACTCAGGCGCCCCGCATTATGCACCACATGCCGGGCCAG CCGCCCTACATGCCGCCCCCTGGTATGATCCCCCCGCCAGGCCTTGCACCTGGCCAGATCCCACCAGGGGCCATGCCCCCGCAGCAGCTT ATGCCAGGACAGATGCCCCCTGCCCAGCCTCTTTCTGAGAATCCACCGAATCACATCTTGTTCCTCACCAACCTGCCAGAGGAGACCAAC GAGCTCATGCTGTCCATGCTTTTCAATCAGTTCCCTGGCTTCAAGGAGGTCCGTCTGGTACCCGGGCGGCATGACATCGCCTTCGTGGAG TTTGACAATGAGGTACAGGCAGGGGCAGCTCGCGATGCCCTGCAGGGCTTTAAGATCACGCAGAACAACGCCATGAAGATCTCCTTTGCC >In-frame_PCID2_ENST00000375479_chr13_113862913_-_SNRPA_ENST00000243563_chr19_41265336_+_639nt ATGGCGCACATTACCATTAACCAGTACCTGCAGCAGCGTATCCAGTATGCCAAGACCGACTCAGATATCATTGCCAAGATGAAAGGCACC TTCGTGGAGCGGGACCGCAAGCGGGAGAAGAGGAAGCCCAAGAGCCAGGAGACCCCGGCCACCAAGAAGGCTGTGCAAGGCGGGGGAGCC ACCCCCGTGGTGGGGGCTGTCCAGGGGCCTGTCCCGGGCATGCCGCCGATGACTCAGGCGCCCCGCATTATGCACCACATGCCGGGCCAG CCGCCCTACATGCCGCCCCCTGGTATGATCCCCCCGCCAGGCCTTGCACCTGGCCAGATCCCACCAGGGGCCATGCCCCCGCAGCAGCTT ATGCCAGGACAGATGCCCCCTGCCCAGCCTCTTTCTGAGAATCCACCGAATCACATCTTGTTCCTCACCAACCTGCCAGAGGAGACCAAC GAGCTCATGCTGTCCATGCTTTTCAATCAGTTCCCTGGCTTCAAGGAGGTCCGTCTGGTACCCGGGCGGCATGACATCGCCTTCGTGGAG TTTGACAATGAGGTACAGGCAGGGGCAGCTCGCGATGCCCTGCAGGGCTTTAAGATCACGCAGAACAACGCCATGAAGATCTCCTTTGCC >In-frame_PCID2_ENST00000246505_chr13_113862913_-_SNRPA_ENST00000243563_chr19_41265336_+_639nt ATGGCGCACATTACCATTAACCAGTACCTGCAGCAGCGTATCCAGTATGCCAAGACCGACTCAGATATCATTGCCAAGATGAAAGGCACC TTCGTGGAGCGGGACCGCAAGCGGGAGAAGAGGAAGCCCAAGAGCCAGGAGACCCCGGCCACCAAGAAGGCTGTGCAAGGCGGGGGAGCC ACCCCCGTGGTGGGGGCTGTCCAGGGGCCTGTCCCGGGCATGCCGCCGATGACTCAGGCGCCCCGCATTATGCACCACATGCCGGGCCAG CCGCCCTACATGCCGCCCCCTGGTATGATCCCCCCGCCAGGCCTTGCACCTGGCCAGATCCCACCAGGGGCCATGCCCCCGCAGCAGCTT ATGCCAGGACAGATGCCCCCTGCCCAGCCTCTTTCTGAGAATCCACCGAATCACATCTTGTTCCTCACCAACCTGCCAGAGGAGACCAAC GAGCTCATGCTGTCCATGCTTTTCAATCAGTTCCCTGGCTTCAAGGAGGTCCGTCTGGTACCCGGGCGGCATGACATCGCCTTCGTGGAG TTTGACAATGAGGTACAGGCAGGGGCAGCTCGCGATGCCCTGCAGGGCTTTAAGATCACGCAGAACAACGCCATGAAGATCTCCTTTGCC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_PCID2_ENST00000337344_chr13_113862913_-_SNRPA_ENST00000243563_chr19_41265336_+_938nt GGACCGAGGGCCGGAAGTGACGCCAGCTGGCCCGCTTGAGGCGTAGGGGGTGGCGCTCTCCGTTCGGCGGCGCTCCCATGGCGCACATTA CCATTAACCAGTACCTGCAGCAGCGTATCCAGTATGCCAAGACCGACTCAGATATCATTGCCAAGATGAAAGGCACCTTCGTGGAGCGGG ACCGCAAGCGGGAGAAGAGGAAGCCCAAGAGCCAGGAGACCCCGGCCACCAAGAAGGCTGTGCAAGGCGGGGGAGCCACCCCCGTGGTGG GGGCTGTCCAGGGGCCTGTCCCGGGCATGCCGCCGATGACTCAGGCGCCCCGCATTATGCACCACATGCCGGGCCAGCCGCCCTACATGC CGCCCCCTGGTATGATCCCCCCGCCAGGCCTTGCACCTGGCCAGATCCCACCAGGGGCCATGCCCCCGCAGCAGCTTATGCCAGGACAGA TGCCCCCTGCCCAGCCTCTTTCTGAGAATCCACCGAATCACATCTTGTTCCTCACCAACCTGCCAGAGGAGACCAACGAGCTCATGCTGT CCATGCTTTTCAATCAGTTCCCTGGCTTCAAGGAGGTCCGTCTGGTACCCGGGCGGCATGACATCGCCTTCGTGGAGTTTGACAATGAGG TACAGGCAGGGGCAGCTCGCGATGCCCTGCAGGGCTTTAAGATCACGCAGAACAACGCCATGAAGATCTCCTTTGCCAAGAAGTAGCACC TTTTCCCCCCATGCCTGCCCCTTCCCCTGTTCTGGGGCCACCCCTTTCCCCCTTGGCTCAGCCCCCTGAAGGTAAGTCCCCCCTTGGGGG CCTTCTTGGAGCCGTGTGTGAGTGAGTGGTCGCCACACAGCATTGTACCCAGAGTCTGTCCCCAGACATTGCACCTGGCGCTGTTAGGCC >In-frame_PCID2_ENST00000375477_chr13_113862913_-_SNRPA_ENST00000243563_chr19_41265336_+_893nt GGGGGTGGCGCTCTCCGTTCGGCGGCGCTCCCATGGCGCACATTACCATTAACCAGTACCTGCAGCAGCGTATCCAGTATGCCAAGACCG ACTCAGATATCATTGCCAAGATGAAAGGCACCTTCGTGGAGCGGGACCGCAAGCGGGAGAAGAGGAAGCCCAAGAGCCAGGAGACCCCGG CCACCAAGAAGGCTGTGCAAGGCGGGGGAGCCACCCCCGTGGTGGGGGCTGTCCAGGGGCCTGTCCCGGGCATGCCGCCGATGACTCAGG CGCCCCGCATTATGCACCACATGCCGGGCCAGCCGCCCTACATGCCGCCCCCTGGTATGATCCCCCCGCCAGGCCTTGCACCTGGCCAGA TCCCACCAGGGGCCATGCCCCCGCAGCAGCTTATGCCAGGACAGATGCCCCCTGCCCAGCCTCTTTCTGAGAATCCACCGAATCACATCT TGTTCCTCACCAACCTGCCAGAGGAGACCAACGAGCTCATGCTGTCCATGCTTTTCAATCAGTTCCCTGGCTTCAAGGAGGTCCGTCTGG TACCCGGGCGGCATGACATCGCCTTCGTGGAGTTTGACAATGAGGTACAGGCAGGGGCAGCTCGCGATGCCCTGCAGGGCTTTAAGATCA CGCAGAACAACGCCATGAAGATCTCCTTTGCCAAGAAGTAGCACCTTTTCCCCCCATGCCTGCCCCTTCCCCTGTTCTGGGGCCACCCCT TTCCCCCTTGGCTCAGCCCCCTGAAGGTAAGTCCCCCCTTGGGGGCCTTCTTGGAGCCGTGTGTGAGTGAGTGGTCGCCACACAGCATTG >In-frame_PCID2_ENST00000375479_chr13_113862913_-_SNRPA_ENST00000243563_chr19_41265336_+_942nt AGACGGACCGAGGGCCGGAAGTGACGCCAGCTGGCCCGCTTGAGGCGTAGGGGGTGGCGCTCTCCGTTCGGCGGCGCTCCCATGGCGCAC ATTACCATTAACCAGTACCTGCAGCAGCGTATCCAGTATGCCAAGACCGACTCAGATATCATTGCCAAGATGAAAGGCACCTTCGTGGAG CGGGACCGCAAGCGGGAGAAGAGGAAGCCCAAGAGCCAGGAGACCCCGGCCACCAAGAAGGCTGTGCAAGGCGGGGGAGCCACCCCCGTG GTGGGGGCTGTCCAGGGGCCTGTCCCGGGCATGCCGCCGATGACTCAGGCGCCCCGCATTATGCACCACATGCCGGGCCAGCCGCCCTAC ATGCCGCCCCCTGGTATGATCCCCCCGCCAGGCCTTGCACCTGGCCAGATCCCACCAGGGGCCATGCCCCCGCAGCAGCTTATGCCAGGA CAGATGCCCCCTGCCCAGCCTCTTTCTGAGAATCCACCGAATCACATCTTGTTCCTCACCAACCTGCCAGAGGAGACCAACGAGCTCATG CTGTCCATGCTTTTCAATCAGTTCCCTGGCTTCAAGGAGGTCCGTCTGGTACCCGGGCGGCATGACATCGCCTTCGTGGAGTTTGACAAT GAGGTACAGGCAGGGGCAGCTCGCGATGCCCTGCAGGGCTTTAAGATCACGCAGAACAACGCCATGAAGATCTCCTTTGCCAAGAAGTAG CACCTTTTCCCCCCATGCCTGCCCCTTCCCCTGTTCTGGGGCCACCCCTTTCCCCCTTGGCTCAGCCCCCTGAAGGTAAGTCCCCCCTTG GGGGCCTTCTTGGAGCCGTGTGTGAGTGAGTGGTCGCCACACAGCATTGTACCCAGAGTCTGTCCCCAGACATTGCACCTGGCGCTGTTA >In-frame_PCID2_ENST00000246505_chr13_113862913_-_SNRPA_ENST00000243563_chr19_41265336_+_896nt GTAGGGGGTGGCGCTCTCCGTTCGGCGGCGCTCCCATGGCGCACATTACCATTAACCAGTACCTGCAGCAGCGTATCCAGTATGCCAAGA CCGACTCAGATATCATTGCCAAGATGAAAGGCACCTTCGTGGAGCGGGACCGCAAGCGGGAGAAGAGGAAGCCCAAGAGCCAGGAGACCC CGGCCACCAAGAAGGCTGTGCAAGGCGGGGGAGCCACCCCCGTGGTGGGGGCTGTCCAGGGGCCTGTCCCGGGCATGCCGCCGATGACTC AGGCGCCCCGCATTATGCACCACATGCCGGGCCAGCCGCCCTACATGCCGCCCCCTGGTATGATCCCCCCGCCAGGCCTTGCACCTGGCC AGATCCCACCAGGGGCCATGCCCCCGCAGCAGCTTATGCCAGGACAGATGCCCCCTGCCCAGCCTCTTTCTGAGAATCCACCGAATCACA TCTTGTTCCTCACCAACCTGCCAGAGGAGACCAACGAGCTCATGCTGTCCATGCTTTTCAATCAGTTCCCTGGCTTCAAGGAGGTCCGTC TGGTACCCGGGCGGCATGACATCGCCTTCGTGGAGTTTGACAATGAGGTACAGGCAGGGGCAGCTCGCGATGCCCTGCAGGGCTTTAAGA TCACGCAGAACAACGCCATGAAGATCTCCTTTGCCAAGAAGTAGCACCTTTTCCCCCCATGCCTGCCCCTTCCCCTGTTCTGGGGCCACC CCTTTCCCCCTTGGCTCAGCCCCCTGAAGGTAAGTCCCCCCTTGGGGGCCTTCTTGGAGCCGTGTGTGAGTGAGTGGTCGCCACACAGCA |
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FusionGenePPI for PCID2_SNRPA |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| PCID2 | SHFM1, NEK6, UBC, CUL3, SMAD2, EID1, TUBGCP3, IKZF3, SHMT2, MOV10, NXF1, CAPZB, DDX3X, IMPDH2, LSM1, ADPRHL2, TTC4, PSMD6, SNX2, SNX6, UBE4B, VPS35, IFI16, KIF11, TMEM63B, ZFC3H1, CETN1, TRIM25 | SNRPA | SNRPA, PTBP1, C19orf43, ATIC, RNPS1, CDC5L, TADA2A, NONO, SFPQ, SF3A2, CUL3, CUL4A, CUL4B, CUL5, CUL2, CDK2, CUL1, COPS5, CAND1, SF3A1, SNRPA1, SF3A3, SF3B1, SF3B3, PRPF19, SRSF11, SF3B5, HNRNPU, GTF2F1, PABPC1, EEF1A1, TST, AHCYL1, EEF1B2, CPLX1, TRIM24, AGMAT, HNRNPH3, TIMM13, TNPO1, SMURF1, FN1, U2AF2, HNRNPK, RBM42, PTBP2, TP63, IFIT1, IFIT2, IFIT3, SMAD5, IL7R, SRPK2, SRPK3, CDKN2A, WBP4, PRKDC, GIT1, LIN28A, LIN28B, CIRBP, GABPB1, PCBP1, PCBP2, RBM3, TRIM27, QKI, ENOX2, MTUS2, NDUFAF3, RBMX, METTL13, LENG8, CUL7, OBSL1, UBC, EZH2, SUZ12, EED, RNF2, PRPF6, YARS, SFN, NTRK1, EWSR1, XPO1, MATR3, SNRPF, SNRPN, SNRNP70, SNRPG, SNRPE |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for PCID2_SNRPA |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for PCID2_SNRPA |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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