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Fusion gene ID: 26220 |
FusionGeneSummary for PCGF3_FANCI |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PCGF3_FANCI | Fusion gene ID: 26220 | Hgene | Tgene | Gene symbol | PCGF3 | FANCI | Gene ID | 10336 | 55215 |
| Gene name | polycomb group ring finger 3 | FA complementation group I | |
| Synonyms | DONG1|RNF3|RNF3A | KIAA1794 | |
| Cytomap | 4p16.3 | 15q26.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | polycomb group RING finger protein 3RING finger protein 3Aring finger protein 3 | Fanconi anemia group I proteinFanconi anemia complementation group I | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q3KNV8 | Q9NVI1 | |
| Ensembl transtripts involved in fusion gene | ENST00000362003, ENST00000400151, ENST00000482726, ENST00000470161, ENST00000521023, ENST00000505655, | ENST00000300027, ENST00000310775, ENST00000451393, ENST00000567996, ENST00000566615, | |
| Fusion gene scores | * DoF score | 11 X 7 X 7=539 | 2 X 2 X 2=8 |
| # samples | 11 | 2 | |
| ** MAII score | log2(11/539*10)=-2.29278174922785 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: PCGF3 [Title/Abstract] AND FANCI [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | FANCI | GO:0031398 | positive regulation of protein ubiquitination | 18029348 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LUSC | TCGA-43-6770-01A | PCGF3 | chr4 | 738476 | + | FANCI | chr15 | 89856135 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000362003 | ENST00000300027 | PCGF3 | chr4 | 738476 | + | FANCI | chr15 | 89856135 | + |
| In-frame | ENST00000362003 | ENST00000310775 | PCGF3 | chr4 | 738476 | + | FANCI | chr15 | 89856135 | + |
| 5CDS-intron | ENST00000362003 | ENST00000451393 | PCGF3 | chr4 | 738476 | + | FANCI | chr15 | 89856135 | + |
| 5CDS-intron | ENST00000362003 | ENST00000567996 | PCGF3 | chr4 | 738476 | + | FANCI | chr15 | 89856135 | + |
| 5CDS-3UTR | ENST00000362003 | ENST00000566615 | PCGF3 | chr4 | 738476 | + | FANCI | chr15 | 89856135 | + |
| intron-3CDS | ENST00000400151 | ENST00000300027 | PCGF3 | chr4 | 738476 | + | FANCI | chr15 | 89856135 | + |
| intron-3CDS | ENST00000400151 | ENST00000310775 | PCGF3 | chr4 | 738476 | + | FANCI | chr15 | 89856135 | + |
| intron-intron | ENST00000400151 | ENST00000451393 | PCGF3 | chr4 | 738476 | + | FANCI | chr15 | 89856135 | + |
| intron-intron | ENST00000400151 | ENST00000567996 | PCGF3 | chr4 | 738476 | + | FANCI | chr15 | 89856135 | + |
| intron-3UTR | ENST00000400151 | ENST00000566615 | PCGF3 | chr4 | 738476 | + | FANCI | chr15 | 89856135 | + |
| intron-3CDS | ENST00000482726 | ENST00000300027 | PCGF3 | chr4 | 738476 | + | FANCI | chr15 | 89856135 | + |
| intron-3CDS | ENST00000482726 | ENST00000310775 | PCGF3 | chr4 | 738476 | + | FANCI | chr15 | 89856135 | + |
| intron-intron | ENST00000482726 | ENST00000451393 | PCGF3 | chr4 | 738476 | + | FANCI | chr15 | 89856135 | + |
| intron-intron | ENST00000482726 | ENST00000567996 | PCGF3 | chr4 | 738476 | + | FANCI | chr15 | 89856135 | + |
| intron-3UTR | ENST00000482726 | ENST00000566615 | PCGF3 | chr4 | 738476 | + | FANCI | chr15 | 89856135 | + |
| In-frame | ENST00000470161 | ENST00000300027 | PCGF3 | chr4 | 738476 | + | FANCI | chr15 | 89856135 | + |
| In-frame | ENST00000470161 | ENST00000310775 | PCGF3 | chr4 | 738476 | + | FANCI | chr15 | 89856135 | + |
| 5CDS-intron | ENST00000470161 | ENST00000451393 | PCGF3 | chr4 | 738476 | + | FANCI | chr15 | 89856135 | + |
| 5CDS-intron | ENST00000470161 | ENST00000567996 | PCGF3 | chr4 | 738476 | + | FANCI | chr15 | 89856135 | + |
| 5CDS-3UTR | ENST00000470161 | ENST00000566615 | PCGF3 | chr4 | 738476 | + | FANCI | chr15 | 89856135 | + |
| In-frame | ENST00000521023 | ENST00000300027 | PCGF3 | chr4 | 738476 | + | FANCI | chr15 | 89856135 | + |
| In-frame | ENST00000521023 | ENST00000310775 | PCGF3 | chr4 | 738476 | + | FANCI | chr15 | 89856135 | + |
| 5CDS-intron | ENST00000521023 | ENST00000451393 | PCGF3 | chr4 | 738476 | + | FANCI | chr15 | 89856135 | + |
| 5CDS-intron | ENST00000521023 | ENST00000567996 | PCGF3 | chr4 | 738476 | + | FANCI | chr15 | 89856135 | + |
| 5CDS-3UTR | ENST00000521023 | ENST00000566615 | PCGF3 | chr4 | 738476 | + | FANCI | chr15 | 89856135 | + |
| In-frame | ENST00000505655 | ENST00000300027 | PCGF3 | chr4 | 738476 | + | FANCI | chr15 | 89856135 | + |
| In-frame | ENST00000505655 | ENST00000310775 | PCGF3 | chr4 | 738476 | + | FANCI | chr15 | 89856135 | + |
| 5CDS-intron | ENST00000505655 | ENST00000451393 | PCGF3 | chr4 | 738476 | + | FANCI | chr15 | 89856135 | + |
| 5CDS-intron | ENST00000505655 | ENST00000567996 | PCGF3 | chr4 | 738476 | + | FANCI | chr15 | 89856135 | + |
| 5CDS-3UTR | ENST00000505655 | ENST00000566615 | PCGF3 | chr4 | 738476 | + | FANCI | chr15 | 89856135 | + |
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FusionProtFeatures for PCGF3_FANCI |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| PCGF3 | FANCI |
| Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain thetranscriptionally repressive state of many genes, including Hoxgenes, throughout development. PcG PRC1 complex acts via chromatinremodeling and modification of histones; it mediatesmonoubiquitination of histone H2A 'Lys-119', rendering chromatinheritably changed in its expressibility. Within the PRC1-likecomplex, regulates RNF2 ubiquitin ligase activity(PubMed:26151332). Plays a redundant role with PCGF5 as part of aPRC1-like complex that mediates monoubiquitination of histone H2A'Lys-119' on the X chromosome and is required for normal silencingof one copy of the X chromosome in XX females (By similarity).{ECO:0000250|UniProtKB:Q8BTQ0, ECO:0000269|PubMed:26151332}. | Plays an essential role in the repair of DNA double-strand breaks by homologous recombination and in the repair ofinterstrand DNA cross-links (ICLs) by promoting FANCD2monoubiquitination by FANCL and participating in recruitment toDNA repair sites. Required for maintenance of chromosomalstability. Specifically binds branched DNA: binds both single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA). Participatesin S phase and G2 phase checkpoint activation upon DNA damage.{ECO:0000269|PubMed:17412408, ECO:0000269|PubMed:17452773,ECO:0000269|PubMed:17460694, ECO:0000269|PubMed:19111657}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | PCGF3 | chr4:738476 | chr15:89856135 | ENST00000362003 | + | 8 | 11 | 17_56 | 154 | 243 | Zinc finger | RING-type |
| Hgene | PCGF3 | chr4:738476 | chr15:89856135 | ENST00000470161 | + | 8 | 11 | 17_56 | 154 | 243 | Zinc finger | RING-type |
| Hgene | PCGF3 | chr4:738476 | chr15:89856135 | ENST00000505655 | + | 6 | 9 | 17_56 | 154 | 243 | Zinc finger | RING-type |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for PCGF3_FANCI |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_PCGF3_ENST00000362003_chr4_738476_+_FANCI_ENST00000300027_chr15_89856135_+_266aa MLTRKIKLWDINAHITCRLCSGYLIDATTVTECLHTFCRSCLVKYLEENNTCPTCRIVIHQSHPLQYIGHDRTMQDIVYKLVPGLQEAEM RKQREFYHKLGMEVPGDIKGETCSAKQHLDSHRNGETKADDSSNKEAAEEKPEEDNDYHRSDEQNKSKSLNYTGEKKEKPAAVATAMARV >In-frame_PCGF3_ENST00000362003_chr4_738476_+_FANCI_ENST00000310775_chr15_89856135_+_266aa MLTRKIKLWDINAHITCRLCSGYLIDATTVTECLHTFCRSCLVKYLEENNTCPTCRIVIHQSHPLQYIGHDRTMQDIVYKLVPGLQEAEM RKQREFYHKLGMEVPGDIKGETCSAKQHLDSHRNGETKADDSSNKEAAEEKPEEDNDYHRSDEQNKSKSLNYTGEKKEKPAAVATAMARV >In-frame_PCGF3_ENST00000470161_chr4_738476_+_FANCI_ENST00000300027_chr15_89856135_+_266aa MLTRKIKLWDINAHITCRLCSGYLIDATTVTECLHTFCRSCLVKYLEENNTCPTCRIVIHQSHPLQYIGHDRTMQDIVYKLVPGLQEAEM RKQREFYHKLGMEVPGDIKGETCSAKQHLDSHRNGETKADDSSNKEAAEEKPEEDNDYHRSDEQNKSKSLNYTGEKKEKPAAVATAMARV >In-frame_PCGF3_ENST00000470161_chr4_738476_+_FANCI_ENST00000310775_chr15_89856135_+_266aa MLTRKIKLWDINAHITCRLCSGYLIDATTVTECLHTFCRSCLVKYLEENNTCPTCRIVIHQSHPLQYIGHDRTMQDIVYKLVPGLQEAEM RKQREFYHKLGMEVPGDIKGETCSAKQHLDSHRNGETKADDSSNKEAAEEKPEEDNDYHRSDEQNKSKSLNYTGEKKEKPAAVATAMARV >In-frame_PCGF3_ENST00000521023_chr4_738476_+_FANCI_ENST00000300027_chr15_89856135_+_232aa MTVCRSCLVKYLEENNTCPTCRIVIHQSHPLQYIGHDRTMQDIVYKLVPGLQEAEMRKQREFYHKLGMEVPGDIKGETCSAKQHLDSHRN GETKADDSSNKEAAEEKPEEDNDYHRSDEQNKSKSLNYTGEKKEKPAAVATAMARVLRETKPIPNLIFAIEQYEKFLIHLSKKSKVNLMQ >In-frame_PCGF3_ENST00000521023_chr4_738476_+_FANCI_ENST00000310775_chr15_89856135_+_232aa MTVCRSCLVKYLEENNTCPTCRIVIHQSHPLQYIGHDRTMQDIVYKLVPGLQEAEMRKQREFYHKLGMEVPGDIKGETCSAKQHLDSHRN GETKADDSSNKEAAEEKPEEDNDYHRSDEQNKSKSLNYTGEKKEKPAAVATAMARVLRETKPIPNLIFAIEQYEKFLIHLSKKSKVNLMQ >In-frame_PCGF3_ENST00000505655_chr4_738476_+_FANCI_ENST00000300027_chr15_89856135_+_266aa MLTRKIKLWDINAHITCRLCSGYLIDATTVTECLHTFCRSCLVKYLEENNTCPTCRIVIHQSHPLQYIGHDRTMQDIVYKLVPGLQEAEM RKQREFYHKLGMEVPGDIKGETCSAKQHLDSHRNGETKADDSSNKEAAEEKPEEDNDYHRSDEQNKSKSLNYTGEKKEKPAAVATAMARV >In-frame_PCGF3_ENST00000505655_chr4_738476_+_FANCI_ENST00000310775_chr15_89856135_+_266aa MLTRKIKLWDINAHITCRLCSGYLIDATTVTECLHTFCRSCLVKYLEENNTCPTCRIVIHQSHPLQYIGHDRTMQDIVYKLVPGLQEAEM RKQREFYHKLGMEVPGDIKGETCSAKQHLDSHRNGETKADDSSNKEAAEEKPEEDNDYHRSDEQNKSKSLNYTGEKKEKPAAVATAMARV |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_PCGF3_ENST00000362003_chr4_738476_+_FANCI_ENST00000300027_chr15_89856135_+_798nt ATGTTGACCAGGAAGATCAAGCTGTGGGACATCAACGCCCACATCACCTGCCGCCTGTGCAGCGGGTACCTCATCGACGCCACCACGGTG ACCGAGTGTCTGCACACCTTCTGCAGGAGCTGCCTGGTGAAGTACCTGGAGGAGAACAACACCTGCCCCACCTGCAGGATTGTGATCCAC CAGAGCCACCCCCTGCAGTACATCGGTCATGACAGAACCATGCAAGATATTGTTTACAAATTGGTACCAGGCCTCCAAGAAGCGGAAATG AGAAAGCAGAGGGAGTTCTATCACAAATTGGGCATGGAGGTGCCGGGAGACATCAAGGGGGAGACCTGCTCTGCAAAACAGCACTTAGAT TCCCATCGGAATGGTGAAACCAAAGCAGACGACAGTTCAAACAAAGAGGCCGCGGAGGAGAAGCCGGAGGAGGACAACGACTACCACCGC AGCGACGAGCAGAATAAGAGTAAGAGCCTGAACTATACGGGAGAGAAAAAGGAGAAACCTGCTGCCGTTGCCACAGCCATGGCCAGAGTT CTTCGGGAAACCAAGCCAATCCCTAACCTCATCTTTGCCATAGAACAGTATGAAAAATTTCTCATCCACCTTTCTAAGAAGTCCAAGGTG AACCTGATGCAGCACATGAAGCTCAGCACCTCACGAGACTTCAAGATCAAAGGAAACATCCTAGACATGGTTCTTCGAGAGGATGGTGAA >In-frame_PCGF3_ENST00000362003_chr4_738476_+_FANCI_ENST00000310775_chr15_89856135_+_798nt ATGTTGACCAGGAAGATCAAGCTGTGGGACATCAACGCCCACATCACCTGCCGCCTGTGCAGCGGGTACCTCATCGACGCCACCACGGTG ACCGAGTGTCTGCACACCTTCTGCAGGAGCTGCCTGGTGAAGTACCTGGAGGAGAACAACACCTGCCCCACCTGCAGGATTGTGATCCAC CAGAGCCACCCCCTGCAGTACATCGGTCATGACAGAACCATGCAAGATATTGTTTACAAATTGGTACCAGGCCTCCAAGAAGCGGAAATG AGAAAGCAGAGGGAGTTCTATCACAAATTGGGCATGGAGGTGCCGGGAGACATCAAGGGGGAGACCTGCTCTGCAAAACAGCACTTAGAT TCCCATCGGAATGGTGAAACCAAAGCAGACGACAGTTCAAACAAAGAGGCCGCGGAGGAGAAGCCGGAGGAGGACAACGACTACCACCGC AGCGACGAGCAGAATAAGAGTAAGAGCCTGAACTATACGGGAGAGAAAAAGGAGAAACCTGCTGCCGTTGCCACAGCCATGGCCAGAGTT CTTCGGGAAACCAAGCCAATCCCTAACCTCATCTTTGCCATAGAACAGTATGAAAAATTTCTCATCCACCTTTCTAAGAAGTCCAAGGTG AACCTGATGCAGCACATGAAGCTCAGCACCTCACGAGACTTCAAGATCAAAGGAAACATCCTAGACATGGTTCTTCGAGAGGATGGTGAA >In-frame_PCGF3_ENST00000470161_chr4_738476_+_FANCI_ENST00000300027_chr15_89856135_+_798nt ATGTTGACCAGGAAGATCAAGCTGTGGGACATCAACGCCCACATCACCTGCCGCCTGTGCAGCGGGTACCTCATCGACGCCACCACGGTG ACCGAGTGTCTGCACACCTTCTGCAGGAGCTGCCTGGTGAAGTACCTGGAGGAGAACAACACCTGCCCCACCTGCAGGATTGTGATCCAC CAGAGCCACCCCCTGCAGTACATCGGTCATGACAGAACCATGCAAGATATTGTTTACAAATTGGTACCAGGCCTCCAAGAAGCGGAAATG AGAAAGCAGAGGGAGTTCTATCACAAATTGGGCATGGAGGTGCCGGGAGACATCAAGGGGGAGACCTGCTCTGCAAAACAGCACTTAGAT TCCCATCGGAATGGTGAAACCAAAGCAGACGACAGTTCAAACAAAGAGGCCGCGGAGGAGAAGCCGGAGGAGGACAACGACTACCACCGC AGCGACGAGCAGAATAAGAGTAAGAGCCTGAACTATACGGGAGAGAAAAAGGAGAAACCTGCTGCCGTTGCCACAGCCATGGCCAGAGTT CTTCGGGAAACCAAGCCAATCCCTAACCTCATCTTTGCCATAGAACAGTATGAAAAATTTCTCATCCACCTTTCTAAGAAGTCCAAGGTG AACCTGATGCAGCACATGAAGCTCAGCACCTCACGAGACTTCAAGATCAAAGGAAACATCCTAGACATGGTTCTTCGAGAGGATGGTGAA >In-frame_PCGF3_ENST00000470161_chr4_738476_+_FANCI_ENST00000310775_chr15_89856135_+_798nt ATGTTGACCAGGAAGATCAAGCTGTGGGACATCAACGCCCACATCACCTGCCGCCTGTGCAGCGGGTACCTCATCGACGCCACCACGGTG ACCGAGTGTCTGCACACCTTCTGCAGGAGCTGCCTGGTGAAGTACCTGGAGGAGAACAACACCTGCCCCACCTGCAGGATTGTGATCCAC CAGAGCCACCCCCTGCAGTACATCGGTCATGACAGAACCATGCAAGATATTGTTTACAAATTGGTACCAGGCCTCCAAGAAGCGGAAATG AGAAAGCAGAGGGAGTTCTATCACAAATTGGGCATGGAGGTGCCGGGAGACATCAAGGGGGAGACCTGCTCTGCAAAACAGCACTTAGAT TCCCATCGGAATGGTGAAACCAAAGCAGACGACAGTTCAAACAAAGAGGCCGCGGAGGAGAAGCCGGAGGAGGACAACGACTACCACCGC AGCGACGAGCAGAATAAGAGTAAGAGCCTGAACTATACGGGAGAGAAAAAGGAGAAACCTGCTGCCGTTGCCACAGCCATGGCCAGAGTT CTTCGGGAAACCAAGCCAATCCCTAACCTCATCTTTGCCATAGAACAGTATGAAAAATTTCTCATCCACCTTTCTAAGAAGTCCAAGGTG AACCTGATGCAGCACATGAAGCTCAGCACCTCACGAGACTTCAAGATCAAAGGAAACATCCTAGACATGGTTCTTCGAGAGGATGGTGAA >In-frame_PCGF3_ENST00000521023_chr4_738476_+_FANCI_ENST00000300027_chr15_89856135_+_696nt ATGACAGTCTGCAGGAGCTGCCTGGTGAAGTACCTGGAGGAGAACAACACCTGCCCCACCTGCAGGATTGTGATCCACCAGAGCCACCCC CTGCAGTACATCGGTCATGACAGAACCATGCAAGATATTGTTTACAAATTGGTACCAGGCCTCCAAGAAGCGGAAATGAGAAAGCAGAGG GAGTTCTATCACAAATTGGGCATGGAGGTGCCGGGAGACATCAAGGGGGAGACCTGCTCTGCAAAACAGCACTTAGATTCCCATCGGAAT GGTGAAACCAAAGCAGACGACAGTTCAAACAAAGAGGCCGCGGAGGAGAAGCCGGAGGAGGACAACGACTACCACCGCAGCGACGAGCAG AATAAGAGTAAGAGCCTGAACTATACGGGAGAGAAAAAGGAGAAACCTGCTGCCGTTGCCACAGCCATGGCCAGAGTTCTTCGGGAAACC AAGCCAATCCCTAACCTCATCTTTGCCATAGAACAGTATGAAAAATTTCTCATCCACCTTTCTAAGAAGTCCAAGGTGAACCTGATGCAG CACATGAAGCTCAGCACCTCACGAGACTTCAAGATCAAAGGAAACATCCTAGACATGGTTCTTCGAGAGGATGGTGAAGATGAAAATGAA >In-frame_PCGF3_ENST00000521023_chr4_738476_+_FANCI_ENST00000310775_chr15_89856135_+_696nt ATGACAGTCTGCAGGAGCTGCCTGGTGAAGTACCTGGAGGAGAACAACACCTGCCCCACCTGCAGGATTGTGATCCACCAGAGCCACCCC CTGCAGTACATCGGTCATGACAGAACCATGCAAGATATTGTTTACAAATTGGTACCAGGCCTCCAAGAAGCGGAAATGAGAAAGCAGAGG GAGTTCTATCACAAATTGGGCATGGAGGTGCCGGGAGACATCAAGGGGGAGACCTGCTCTGCAAAACAGCACTTAGATTCCCATCGGAAT GGTGAAACCAAAGCAGACGACAGTTCAAACAAAGAGGCCGCGGAGGAGAAGCCGGAGGAGGACAACGACTACCACCGCAGCGACGAGCAG AATAAGAGTAAGAGCCTGAACTATACGGGAGAGAAAAAGGAGAAACCTGCTGCCGTTGCCACAGCCATGGCCAGAGTTCTTCGGGAAACC AAGCCAATCCCTAACCTCATCTTTGCCATAGAACAGTATGAAAAATTTCTCATCCACCTTTCTAAGAAGTCCAAGGTGAACCTGATGCAG CACATGAAGCTCAGCACCTCACGAGACTTCAAGATCAAAGGAAACATCCTAGACATGGTTCTTCGAGAGGATGGTGAAGATGAAAATGAA >In-frame_PCGF3_ENST00000505655_chr4_738476_+_FANCI_ENST00000300027_chr15_89856135_+_798nt ATGTTGACCAGGAAGATCAAGCTGTGGGACATCAACGCCCACATCACCTGCCGCCTGTGCAGCGGGTACCTCATCGACGCCACCACGGTG ACCGAGTGTCTGCACACCTTCTGCAGGAGCTGCCTGGTGAAGTACCTGGAGGAGAACAACACCTGCCCCACCTGCAGGATTGTGATCCAC CAGAGCCACCCCCTGCAGTACATCGGTCATGACAGAACCATGCAAGATATTGTTTACAAATTGGTACCAGGCCTCCAAGAAGCGGAAATG AGAAAGCAGAGGGAGTTCTATCACAAATTGGGCATGGAGGTGCCGGGAGACATCAAGGGGGAGACCTGCTCTGCAAAACAGCACTTAGAT TCCCATCGGAATGGTGAAACCAAAGCAGACGACAGTTCAAACAAAGAGGCCGCGGAGGAGAAGCCGGAGGAGGACAACGACTACCACCGC AGCGACGAGCAGAATAAGAGTAAGAGCCTGAACTATACGGGAGAGAAAAAGGAGAAACCTGCTGCCGTTGCCACAGCCATGGCCAGAGTT CTTCGGGAAACCAAGCCAATCCCTAACCTCATCTTTGCCATAGAACAGTATGAAAAATTTCTCATCCACCTTTCTAAGAAGTCCAAGGTG AACCTGATGCAGCACATGAAGCTCAGCACCTCACGAGACTTCAAGATCAAAGGAAACATCCTAGACATGGTTCTTCGAGAGGATGGTGAA >In-frame_PCGF3_ENST00000505655_chr4_738476_+_FANCI_ENST00000310775_chr15_89856135_+_798nt ATGTTGACCAGGAAGATCAAGCTGTGGGACATCAACGCCCACATCACCTGCCGCCTGTGCAGCGGGTACCTCATCGACGCCACCACGGTG ACCGAGTGTCTGCACACCTTCTGCAGGAGCTGCCTGGTGAAGTACCTGGAGGAGAACAACACCTGCCCCACCTGCAGGATTGTGATCCAC CAGAGCCACCCCCTGCAGTACATCGGTCATGACAGAACCATGCAAGATATTGTTTACAAATTGGTACCAGGCCTCCAAGAAGCGGAAATG AGAAAGCAGAGGGAGTTCTATCACAAATTGGGCATGGAGGTGCCGGGAGACATCAAGGGGGAGACCTGCTCTGCAAAACAGCACTTAGAT TCCCATCGGAATGGTGAAACCAAAGCAGACGACAGTTCAAACAAAGAGGCCGCGGAGGAGAAGCCGGAGGAGGACAACGACTACCACCGC AGCGACGAGCAGAATAAGAGTAAGAGCCTGAACTATACGGGAGAGAAAAAGGAGAAACCTGCTGCCGTTGCCACAGCCATGGCCAGAGTT CTTCGGGAAACCAAGCCAATCCCTAACCTCATCTTTGCCATAGAACAGTATGAAAAATTTCTCATCCACCTTTCTAAGAAGTCCAAGGTG AACCTGATGCAGCACATGAAGCTCAGCACCTCACGAGACTTCAAGATCAAAGGAAACATCCTAGACATGGTTCTTCGAGAGGATGGTGAA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_PCGF3_ENST00000362003_chr4_738476_+_FANCI_ENST00000300027_chr15_89856135_+_1995nt GCCCAGACGCACACCGCGCATGCTCCGAGCGCGGCGCCCCCGACGCGGCGCTCGGCTCGGCTCGGGCATTTCCGCCTCTTTGTTTTAAAC TCCGGACGGGCTTTTTTCTCCTCCTCTTGGGGGGGACCCAGAGGGAGCGGCGCCCCCTCCCCCCTCCGGCGCGGACCCCGCGTGCGCCTT GCTCGCCCGCAGCCCCGAGACCGCAGGCGTCACAATGTAGCAGGGACCCCAGGCGTCGTGCTCAGAAAATGGAAAAAGAGCCAGGGCCGG AAGGAGGGTGCAGAAGCGAGTCCGCGTGCGGAGCCAGGAGGCAGCGTCGCGTGGGAGTGCTGGCCTGAAGCCTCCATGCCCCGGCAGAGG GACGGACACGCGGACGTCTAGCGGAGAAGCCAAAGATGTTGACCAGGAAGATCAAGCTGTGGGACATCAACGCCCACATCACCTGCCGCC TGTGCAGCGGGTACCTCATCGACGCCACCACGGTGACCGAGTGTCTGCACACCTTCTGCAGGAGCTGCCTGGTGAAGTACCTGGAGGAGA ACAACACCTGCCCCACCTGCAGGATTGTGATCCACCAGAGCCACCCCCTGCAGTACATCGGTCATGACAGAACCATGCAAGATATTGTTT ACAAATTGGTACCAGGCCTCCAAGAAGCGGAAATGAGAAAGCAGAGGGAGTTCTATCACAAATTGGGCATGGAGGTGCCGGGAGACATCA AGGGGGAGACCTGCTCTGCAAAACAGCACTTAGATTCCCATCGGAATGGTGAAACCAAAGCAGACGACAGTTCAAACAAAGAGGCCGCGG AGGAGAAGCCGGAGGAGGACAACGACTACCACCGCAGCGACGAGCAGAATAAGAGTAAGAGCCTGAACTATACGGGAGAGAAAAAGGAGA AACCTGCTGCCGTTGCCACAGCCATGGCCAGAGTTCTTCGGGAAACCAAGCCAATCCCTAACCTCATCTTTGCCATAGAACAGTATGAAA AATTTCTCATCCACCTTTCTAAGAAGTCCAAGGTGAACCTGATGCAGCACATGAAGCTCAGCACCTCACGAGACTTCAAGATCAAAGGAA ACATCCTAGACATGGTTCTTCGAGAGGATGGTGAAGATGAAAATGAAGAGGGCACTGCATCAGAGCATGGGGGACAGAACAAAGAACCAG CCAAGAAGAAAAGGAAAAAATAAATGAAATGCCTGAGTTAATGTGAACTTTGGGGCTTCTGCTTCATTTTTACCCAACAAGCAACAATGC CCCTTGTCCTGTAGTCCACACCGATGTTGGCATCTTGGTTCTGAACCCACTGAATTCAACTGCACCTTCAGTTAGAAGGAATCTTCTTGG CAGGTCCTGCTACTGAAAAATGGCTGGCCTTAGGCAAGCCCTTTTGCAAAAAGCACAGCTGAAAGCCTGAGTTTGGGAGCCTGCACCACC CCGATGAAGCTCCACGGGAGCAAATACAGAGCCTCCAGGCAGTGCTATGGTCCAGGCTGGCTTCGTTTTTCCAAGGAGCCTTTGGTGAGT TCAATTATCTGGTAAATATCCAGCGCTTCACCTGAAAGATAGTGCAAATTGGTTAGGATGCCACCTCAAGAACTGTAACTGAGAGCTCAG AAGTGAGCAAAGGAGCTTAATGCTAAGGTCAAAAGGAGAGTGAAAGGTTGAGAACAATTGCCACGAACGGTAATGTTACATGTTAGGAGG GTCTGTTTTCTTTTTATATAAGTGTGTCTTAGATATATTTTAAATAGAAAATAAGCTTTCTGATTTACTTGTTTGGTATTTAAAGCACAG TTTGTTTTTCTGTCACCTATAGAGTGCAAGAATGCACTCTATAGAATAAATTATCTTTAAACATTTCTTCTGTGGTTGAAGTAGGGGACA GGTACAGGTAGAATATTTGAAGCTCTGCTGCCTTCATTTCTGAAACATCATATCACATTCACTCTGGACACAGGGCACCTTATAAACTGA >In-frame_PCGF3_ENST00000362003_chr4_738476_+_FANCI_ENST00000310775_chr15_89856135_+_1863nt GCCCAGACGCACACCGCGCATGCTCCGAGCGCGGCGCCCCCGACGCGGCGCTCGGCTCGGCTCGGGCATTTCCGCCTCTTTGTTTTAAAC TCCGGACGGGCTTTTTTCTCCTCCTCTTGGGGGGGACCCAGAGGGAGCGGCGCCCCCTCCCCCCTCCGGCGCGGACCCCGCGTGCGCCTT GCTCGCCCGCAGCCCCGAGACCGCAGGCGTCACAATGTAGCAGGGACCCCAGGCGTCGTGCTCAGAAAATGGAAAAAGAGCCAGGGCCGG AAGGAGGGTGCAGAAGCGAGTCCGCGTGCGGAGCCAGGAGGCAGCGTCGCGTGGGAGTGCTGGCCTGAAGCCTCCATGCCCCGGCAGAGG GACGGACACGCGGACGTCTAGCGGAGAAGCCAAAGATGTTGACCAGGAAGATCAAGCTGTGGGACATCAACGCCCACATCACCTGCCGCC TGTGCAGCGGGTACCTCATCGACGCCACCACGGTGACCGAGTGTCTGCACACCTTCTGCAGGAGCTGCCTGGTGAAGTACCTGGAGGAGA ACAACACCTGCCCCACCTGCAGGATTGTGATCCACCAGAGCCACCCCCTGCAGTACATCGGTCATGACAGAACCATGCAAGATATTGTTT ACAAATTGGTACCAGGCCTCCAAGAAGCGGAAATGAGAAAGCAGAGGGAGTTCTATCACAAATTGGGCATGGAGGTGCCGGGAGACATCA AGGGGGAGACCTGCTCTGCAAAACAGCACTTAGATTCCCATCGGAATGGTGAAACCAAAGCAGACGACAGTTCAAACAAAGAGGCCGCGG AGGAGAAGCCGGAGGAGGACAACGACTACCACCGCAGCGACGAGCAGAATAAGAGTAAGAGCCTGAACTATACGGGAGAGAAAAAGGAGA AACCTGCTGCCGTTGCCACAGCCATGGCCAGAGTTCTTCGGGAAACCAAGCCAATCCCTAACCTCATCTTTGCCATAGAACAGTATGAAA AATTTCTCATCCACCTTTCTAAGAAGTCCAAGGTGAACCTGATGCAGCACATGAAGCTCAGCACCTCACGAGACTTCAAGATCAAAGGAA ACATCCTAGACATGGTTCTTCGAGAGGATGGTGAAGATGAAAATGAAGAGGGCACTGCATCAGAGCATGGGGGACAGAACAAAGAACCAG CCAAGAAGAAAAGGAAAAAATAAATGAAATGCCTGAGTTAATGTGAACTTTGGGGCTTCTGCTTCATTTTTACCCAACAAGCAACAATGC CCCTTGTCCTGTAGTCCACACCGATGTTGGCATCTTGGTTCTGAACCCACTGAATTCAACTGCACCTTCAGTTAGAAGGAATCTTCTTGG CAGGTCCTGCTACTGAAAAATGGCTGGCCTTAGGCAAGCCCTTTTGCAAAAAGCACAGCTGAAAGCCTGAGTTTGGGAGCCTGCACCACC CCGATGAAGCTCCACGGGAGCAAATACAGAGCCTCCAGGCAGTGCTATGGTCCAGGCTGGCTTCGTTTTTCCAAGGAGCCTTTGGTGAGT TCAATTATCTGGTAAATATCCAGCGCTTCACCTGAAAGATAGTGCAAATTGGTTAGGATGCCACCTCAAGAACTGTAACTGAGAGCTCAG AAGTGAGCAAAGGAGCTTAATGCTAAGGTCAAAAGGAGAGTGAAAGGTTGAGAACAATTGCCACGAACGGTAATGTTACATGTTAGGAGG GTCTGTTTTCTTTTTATATAAGTGTGTCTTAGATATATTTTAAATAGAAAATAAGCTTTCTGATTTACTTGTTTGGTATTTAAAGCACAG >In-frame_PCGF3_ENST00000470161_chr4_738476_+_FANCI_ENST00000300027_chr15_89856135_+_1994nt ATGCTCCGAGCGCGGCGCCCCCGACGCGGCGCTCGGCTCGGCTCGGGCATTTCCGCCTCTTTGTTTTAAACTCCGGACGGGCTTTTTTCT CCTCCTCTTGGGGGGGACCCAGAGGGAGCGGCGCCCCCTCCCCCCTCCGGCGCGGACCCCGCGTGCGCCTTGCTCGCCCGCAGCCCCGAG ACCGCAGGCGTCACAATGTAGCAGGGACCCCAGGCGTCGTGCTCAGGTGCCGTTTCTGTGCTAGAAAATGGAAAAAGAGCCAGGGCCGGA AGGAGGGTGCAGAAGCGAGTCCGCGTGCGGAGCCAGGAGGCAGCGTCGCGTGGGAGTGCTGGCCTGAAGCCTCCATGCCCCGGCAGAGGG ACGGACACGCGGACGTCTAGCGGAGAAGCCAAAGATGTTGACCAGGAAGATCAAGCTGTGGGACATCAACGCCCACATCACCTGCCGCCT GTGCAGCGGGTACCTCATCGACGCCACCACGGTGACCGAGTGTCTGCACACCTTCTGCAGGAGCTGCCTGGTGAAGTACCTGGAGGAGAA CAACACCTGCCCCACCTGCAGGATTGTGATCCACCAGAGCCACCCCCTGCAGTACATCGGTCATGACAGAACCATGCAAGATATTGTTTA CAAATTGGTACCAGGCCTCCAAGAAGCGGAAATGAGAAAGCAGAGGGAGTTCTATCACAAATTGGGCATGGAGGTGCCGGGAGACATCAA GGGGGAGACCTGCTCTGCAAAACAGCACTTAGATTCCCATCGGAATGGTGAAACCAAAGCAGACGACAGTTCAAACAAAGAGGCCGCGGA GGAGAAGCCGGAGGAGGACAACGACTACCACCGCAGCGACGAGCAGAATAAGAGTAAGAGCCTGAACTATACGGGAGAGAAAAAGGAGAA ACCTGCTGCCGTTGCCACAGCCATGGCCAGAGTTCTTCGGGAAACCAAGCCAATCCCTAACCTCATCTTTGCCATAGAACAGTATGAAAA ATTTCTCATCCACCTTTCTAAGAAGTCCAAGGTGAACCTGATGCAGCACATGAAGCTCAGCACCTCACGAGACTTCAAGATCAAAGGAAA CATCCTAGACATGGTTCTTCGAGAGGATGGTGAAGATGAAAATGAAGAGGGCACTGCATCAGAGCATGGGGGACAGAACAAAGAACCAGC CAAGAAGAAAAGGAAAAAATAAATGAAATGCCTGAGTTAATGTGAACTTTGGGGCTTCTGCTTCATTTTTACCCAACAAGCAACAATGCC CCTTGTCCTGTAGTCCACACCGATGTTGGCATCTTGGTTCTGAACCCACTGAATTCAACTGCACCTTCAGTTAGAAGGAATCTTCTTGGC AGGTCCTGCTACTGAAAAATGGCTGGCCTTAGGCAAGCCCTTTTGCAAAAAGCACAGCTGAAAGCCTGAGTTTGGGAGCCTGCACCACCC CGATGAAGCTCCACGGGAGCAAATACAGAGCCTCCAGGCAGTGCTATGGTCCAGGCTGGCTTCGTTTTTCCAAGGAGCCTTTGGTGAGTT CAATTATCTGGTAAATATCCAGCGCTTCACCTGAAAGATAGTGCAAATTGGTTAGGATGCCACCTCAAGAACTGTAACTGAGAGCTCAGA AGTGAGCAAAGGAGCTTAATGCTAAGGTCAAAAGGAGAGTGAAAGGTTGAGAACAATTGCCACGAACGGTAATGTTACATGTTAGGAGGG TCTGTTTTCTTTTTATATAAGTGTGTCTTAGATATATTTTAAATAGAAAATAAGCTTTCTGATTTACTTGTTTGGTATTTAAAGCACAGT TTGTTTTTCTGTCACCTATAGAGTGCAAGAATGCACTCTATAGAATAAATTATCTTTAAACATTTCTTCTGTGGTTGAAGTAGGGGACAG GTACAGGTAGAATATTTGAAGCTCTGCTGCCTTCATTTCTGAAACATCATATCACATTCACTCTGGACACAGGGCACCTTATAAACTGAA >In-frame_PCGF3_ENST00000470161_chr4_738476_+_FANCI_ENST00000310775_chr15_89856135_+_1862nt ATGCTCCGAGCGCGGCGCCCCCGACGCGGCGCTCGGCTCGGCTCGGGCATTTCCGCCTCTTTGTTTTAAACTCCGGACGGGCTTTTTTCT CCTCCTCTTGGGGGGGACCCAGAGGGAGCGGCGCCCCCTCCCCCCTCCGGCGCGGACCCCGCGTGCGCCTTGCTCGCCCGCAGCCCCGAG ACCGCAGGCGTCACAATGTAGCAGGGACCCCAGGCGTCGTGCTCAGGTGCCGTTTCTGTGCTAGAAAATGGAAAAAGAGCCAGGGCCGGA AGGAGGGTGCAGAAGCGAGTCCGCGTGCGGAGCCAGGAGGCAGCGTCGCGTGGGAGTGCTGGCCTGAAGCCTCCATGCCCCGGCAGAGGG ACGGACACGCGGACGTCTAGCGGAGAAGCCAAAGATGTTGACCAGGAAGATCAAGCTGTGGGACATCAACGCCCACATCACCTGCCGCCT GTGCAGCGGGTACCTCATCGACGCCACCACGGTGACCGAGTGTCTGCACACCTTCTGCAGGAGCTGCCTGGTGAAGTACCTGGAGGAGAA CAACACCTGCCCCACCTGCAGGATTGTGATCCACCAGAGCCACCCCCTGCAGTACATCGGTCATGACAGAACCATGCAAGATATTGTTTA CAAATTGGTACCAGGCCTCCAAGAAGCGGAAATGAGAAAGCAGAGGGAGTTCTATCACAAATTGGGCATGGAGGTGCCGGGAGACATCAA GGGGGAGACCTGCTCTGCAAAACAGCACTTAGATTCCCATCGGAATGGTGAAACCAAAGCAGACGACAGTTCAAACAAAGAGGCCGCGGA GGAGAAGCCGGAGGAGGACAACGACTACCACCGCAGCGACGAGCAGAATAAGAGTAAGAGCCTGAACTATACGGGAGAGAAAAAGGAGAA ACCTGCTGCCGTTGCCACAGCCATGGCCAGAGTTCTTCGGGAAACCAAGCCAATCCCTAACCTCATCTTTGCCATAGAACAGTATGAAAA ATTTCTCATCCACCTTTCTAAGAAGTCCAAGGTGAACCTGATGCAGCACATGAAGCTCAGCACCTCACGAGACTTCAAGATCAAAGGAAA CATCCTAGACATGGTTCTTCGAGAGGATGGTGAAGATGAAAATGAAGAGGGCACTGCATCAGAGCATGGGGGACAGAACAAAGAACCAGC CAAGAAGAAAAGGAAAAAATAAATGAAATGCCTGAGTTAATGTGAACTTTGGGGCTTCTGCTTCATTTTTACCCAACAAGCAACAATGCC CCTTGTCCTGTAGTCCACACCGATGTTGGCATCTTGGTTCTGAACCCACTGAATTCAACTGCACCTTCAGTTAGAAGGAATCTTCTTGGC AGGTCCTGCTACTGAAAAATGGCTGGCCTTAGGCAAGCCCTTTTGCAAAAAGCACAGCTGAAAGCCTGAGTTTGGGAGCCTGCACCACCC CGATGAAGCTCCACGGGAGCAAATACAGAGCCTCCAGGCAGTGCTATGGTCCAGGCTGGCTTCGTTTTTCCAAGGAGCCTTTGGTGAGTT CAATTATCTGGTAAATATCCAGCGCTTCACCTGAAAGATAGTGCAAATTGGTTAGGATGCCACCTCAAGAACTGTAACTGAGAGCTCAGA AGTGAGCAAAGGAGCTTAATGCTAAGGTCAAAAGGAGAGTGAAAGGTTGAGAACAATTGCCACGAACGGTAATGTTACATGTTAGGAGGG TCTGTTTTCTTTTTATATAAGTGTGTCTTAGATATATTTTAAATAGAAAATAAGCTTTCTGATTTACTTGTTTGGTATTTAAAGCACAGT >In-frame_PCGF3_ENST00000521023_chr4_738476_+_FANCI_ENST00000300027_chr15_89856135_+_2963nt TTGCTCGCCCGCAGCCCCGAGACCGCAGGCGTCACAATGTAGCAGGGACCCCAGGCGTCGTGCTCAGAAAATGGAAAAAGAGCCAGGGCC GGAAGGAGGGTGCAGAAGCGAGTCCGCGTGCGGAGCCAGGAGGCAGCGTCGCGTGGGAGTGCTGGCCTGAAGCCTCCATGCCCCGGCAGA GGGACGGACACGCGGACGTCTAGCGGAGGCTCCCGTGTCCTCAGTATGCATCAGGTCTCCCGAACCTCACAGCCCCGCAGGGAGGAGGAG AAGGGGAGGATTTGACTTTGGAAGTCTCTGTGACCAGAAGCCAAAGATGTTGACCAGGAAGATCAAGCTGTGGGACATCAACGCCCACAT CACCTGCCGCCTGTGCAGCGGGTACCTCATCGACGCCACCACGGTGACCGAGTGTCTGCACACCTCTCAAGCCCGACAAAAGCAGGAACC AGGACCAGGGGCAGAGACGATCTTGAAGATAAGTCAGAAAAGTCATTTCACGCTAAAGGTCCTGTGGGTGGTGTCAGAGCAGATGAGGCC TCGCTTAGGAGAGCGAAACACAGGAGAGACCCCACATTCCTCCCACGGAGCAGCAAGGCCAGTAGCCGCTGTGACAGTGCTCACTGCTGG CAGTTTCCAAATCTCCAGAGGAGTTCCTTAGATCCTTCAAAGGGGAACCTTCCAGTGTGTTCTTCACACCTGATGTGCGTCCTCACACCT GATGAGTCTGTGCTTTGGTGTTAGAGGACTCACACCTGGGGCTGGACCTGAGTGTTTTTCTAAGTGTGGCTACCGCTGACGGGCAGGTGC CATCCATCAGGCTGAGGCTCGGCTCTTATGCTAACCTGAGGCCCCATGGCTGGCGGCCCTGCTGGTGTGGACGACCGCTGTGTGCGTCTC TTGATGGCTGGGGAGCATTTTGTTTAAACAGGATCTTTAAAATGAAGTGTACGCTTATAATACAAGTGATGCTTGTGTATTTCTCACTTT AGGAAATAAAATATTTGCCAATTTGATAGAATTTTGACTTTAACGTTAATCGTATTTTTAGATATTGGTTAGCATATTTTATGTTAGGTT ATTTTCATTTGATTTTATCTAGTTGTACGTAGAAGATACTGTCATCTTTTAGGACAAAGTATTGTAAAATTATCTGTTTTAGCCCATGTT CTGATGACCCACAGCTCTGTCACCTTTGAGCATCATCTCCCCATTCTAAGTTTTTTTCCCACTTAATTCCTAACCCTGCCTCTTTGAGGA AGCCCATTGACGGGGCAATTAAAACCTTCTCATTGCTCCTGAGACCAGAACGGCAAGATGTTTCCTTTCAGAAGCTGAGAGCCACAAGGA GGACAGCAGTGAGCATCTGCACAGAAACGAGCTCAGAGACGCCCGTGTTCAGTGGAGCACGCCGATGGGGTGGGCGCCCTGGCTCTAGAC GCTCTCCTAACACACCTGTGCTTTGATGACAGTCTGCAGGAGCTGCCTGGTGAAGTACCTGGAGGAGAACAACACCTGCCCCACCTGCAG GATTGTGATCCACCAGAGCCACCCCCTGCAGTACATCGGTCATGACAGAACCATGCAAGATATTGTTTACAAATTGGTACCAGGCCTCCA AGAAGCGGAAATGAGAAAGCAGAGGGAGTTCTATCACAAATTGGGCATGGAGGTGCCGGGAGACATCAAGGGGGAGACCTGCTCTGCAAA ACAGCACTTAGATTCCCATCGGAATGGTGAAACCAAAGCAGACGACAGTTCAAACAAAGAGGCCGCGGAGGAGAAGCCGGAGGAGGACAA CGACTACCACCGCAGCGACGAGCAGAATAAGAGTAAGAGCCTGAACTATACGGGAGAGAAAAAGGAGAAACCTGCTGCCGTTGCCACAGC CATGGCCAGAGTTCTTCGGGAAACCAAGCCAATCCCTAACCTCATCTTTGCCATAGAACAGTATGAAAAATTTCTCATCCACCTTTCTAA GAAGTCCAAGGTGAACCTGATGCAGCACATGAAGCTCAGCACCTCACGAGACTTCAAGATCAAAGGAAACATCCTAGACATGGTTCTTCG AGAGGATGGTGAAGATGAAAATGAAGAGGGCACTGCATCAGAGCATGGGGGACAGAACAAAGAACCAGCCAAGAAGAAAAGGAAAAAATA AATGAAATGCCTGAGTTAATGTGAACTTTGGGGCTTCTGCTTCATTTTTACCCAACAAGCAACAATGCCCCTTGTCCTGTAGTCCACACC GATGTTGGCATCTTGGTTCTGAACCCACTGAATTCAACTGCACCTTCAGTTAGAAGGAATCTTCTTGGCAGGTCCTGCTACTGAAAAATG GCTGGCCTTAGGCAAGCCCTTTTGCAAAAAGCACAGCTGAAAGCCTGAGTTTGGGAGCCTGCACCACCCCGATGAAGCTCCACGGGAGCA AATACAGAGCCTCCAGGCAGTGCTATGGTCCAGGCTGGCTTCGTTTTTCCAAGGAGCCTTTGGTGAGTTCAATTATCTGGTAAATATCCA GCGCTTCACCTGAAAGATAGTGCAAATTGGTTAGGATGCCACCTCAAGAACTGTAACTGAGAGCTCAGAAGTGAGCAAAGGAGCTTAATG CTAAGGTCAAAAGGAGAGTGAAAGGTTGAGAACAATTGCCACGAACGGTAATGTTACATGTTAGGAGGGTCTGTTTTCTTTTTATATAAG TGTGTCTTAGATATATTTTAAATAGAAAATAAGCTTTCTGATTTACTTGTTTGGTATTTAAAGCACAGTTTGTTTTTCTGTCACCTATAG AGTGCAAGAATGCACTCTATAGAATAAATTATCTTTAAACATTTCTTCTGTGGTTGAAGTAGGGGACAGGTACAGGTAGAATATTTGAAG >In-frame_PCGF3_ENST00000521023_chr4_738476_+_FANCI_ENST00000310775_chr15_89856135_+_2831nt TTGCTCGCCCGCAGCCCCGAGACCGCAGGCGTCACAATGTAGCAGGGACCCCAGGCGTCGTGCTCAGAAAATGGAAAAAGAGCCAGGGCC GGAAGGAGGGTGCAGAAGCGAGTCCGCGTGCGGAGCCAGGAGGCAGCGTCGCGTGGGAGTGCTGGCCTGAAGCCTCCATGCCCCGGCAGA GGGACGGACACGCGGACGTCTAGCGGAGGCTCCCGTGTCCTCAGTATGCATCAGGTCTCCCGAACCTCACAGCCCCGCAGGGAGGAGGAG AAGGGGAGGATTTGACTTTGGAAGTCTCTGTGACCAGAAGCCAAAGATGTTGACCAGGAAGATCAAGCTGTGGGACATCAACGCCCACAT CACCTGCCGCCTGTGCAGCGGGTACCTCATCGACGCCACCACGGTGACCGAGTGTCTGCACACCTCTCAAGCCCGACAAAAGCAGGAACC AGGACCAGGGGCAGAGACGATCTTGAAGATAAGTCAGAAAAGTCATTTCACGCTAAAGGTCCTGTGGGTGGTGTCAGAGCAGATGAGGCC TCGCTTAGGAGAGCGAAACACAGGAGAGACCCCACATTCCTCCCACGGAGCAGCAAGGCCAGTAGCCGCTGTGACAGTGCTCACTGCTGG CAGTTTCCAAATCTCCAGAGGAGTTCCTTAGATCCTTCAAAGGGGAACCTTCCAGTGTGTTCTTCACACCTGATGTGCGTCCTCACACCT GATGAGTCTGTGCTTTGGTGTTAGAGGACTCACACCTGGGGCTGGACCTGAGTGTTTTTCTAAGTGTGGCTACCGCTGACGGGCAGGTGC CATCCATCAGGCTGAGGCTCGGCTCTTATGCTAACCTGAGGCCCCATGGCTGGCGGCCCTGCTGGTGTGGACGACCGCTGTGTGCGTCTC TTGATGGCTGGGGAGCATTTTGTTTAAACAGGATCTTTAAAATGAAGTGTACGCTTATAATACAAGTGATGCTTGTGTATTTCTCACTTT AGGAAATAAAATATTTGCCAATTTGATAGAATTTTGACTTTAACGTTAATCGTATTTTTAGATATTGGTTAGCATATTTTATGTTAGGTT ATTTTCATTTGATTTTATCTAGTTGTACGTAGAAGATACTGTCATCTTTTAGGACAAAGTATTGTAAAATTATCTGTTTTAGCCCATGTT CTGATGACCCACAGCTCTGTCACCTTTGAGCATCATCTCCCCATTCTAAGTTTTTTTCCCACTTAATTCCTAACCCTGCCTCTTTGAGGA AGCCCATTGACGGGGCAATTAAAACCTTCTCATTGCTCCTGAGACCAGAACGGCAAGATGTTTCCTTTCAGAAGCTGAGAGCCACAAGGA GGACAGCAGTGAGCATCTGCACAGAAACGAGCTCAGAGACGCCCGTGTTCAGTGGAGCACGCCGATGGGGTGGGCGCCCTGGCTCTAGAC GCTCTCCTAACACACCTGTGCTTTGATGACAGTCTGCAGGAGCTGCCTGGTGAAGTACCTGGAGGAGAACAACACCTGCCCCACCTGCAG GATTGTGATCCACCAGAGCCACCCCCTGCAGTACATCGGTCATGACAGAACCATGCAAGATATTGTTTACAAATTGGTACCAGGCCTCCA AGAAGCGGAAATGAGAAAGCAGAGGGAGTTCTATCACAAATTGGGCATGGAGGTGCCGGGAGACATCAAGGGGGAGACCTGCTCTGCAAA ACAGCACTTAGATTCCCATCGGAATGGTGAAACCAAAGCAGACGACAGTTCAAACAAAGAGGCCGCGGAGGAGAAGCCGGAGGAGGACAA CGACTACCACCGCAGCGACGAGCAGAATAAGAGTAAGAGCCTGAACTATACGGGAGAGAAAAAGGAGAAACCTGCTGCCGTTGCCACAGC CATGGCCAGAGTTCTTCGGGAAACCAAGCCAATCCCTAACCTCATCTTTGCCATAGAACAGTATGAAAAATTTCTCATCCACCTTTCTAA GAAGTCCAAGGTGAACCTGATGCAGCACATGAAGCTCAGCACCTCACGAGACTTCAAGATCAAAGGAAACATCCTAGACATGGTTCTTCG AGAGGATGGTGAAGATGAAAATGAAGAGGGCACTGCATCAGAGCATGGGGGACAGAACAAAGAACCAGCCAAGAAGAAAAGGAAAAAATA AATGAAATGCCTGAGTTAATGTGAACTTTGGGGCTTCTGCTTCATTTTTACCCAACAAGCAACAATGCCCCTTGTCCTGTAGTCCACACC GATGTTGGCATCTTGGTTCTGAACCCACTGAATTCAACTGCACCTTCAGTTAGAAGGAATCTTCTTGGCAGGTCCTGCTACTGAAAAATG GCTGGCCTTAGGCAAGCCCTTTTGCAAAAAGCACAGCTGAAAGCCTGAGTTTGGGAGCCTGCACCACCCCGATGAAGCTCCACGGGAGCA AATACAGAGCCTCCAGGCAGTGCTATGGTCCAGGCTGGCTTCGTTTTTCCAAGGAGCCTTTGGTGAGTTCAATTATCTGGTAAATATCCA GCGCTTCACCTGAAAGATAGTGCAAATTGGTTAGGATGCCACCTCAAGAACTGTAACTGAGAGCTCAGAAGTGAGCAAAGGAGCTTAATG CTAAGGTCAAAAGGAGAGTGAAAGGTTGAGAACAATTGCCACGAACGGTAATGTTACATGTTAGGAGGGTCTGTTTTCTTTTTATATAAG TGTGTCTTAGATATATTTTAAATAGAAAATAAGCTTTCTGATTTACTTGTTTGGTATTTAAAGCACAGTTTGTTTTTCTGTCACCTATAG >In-frame_PCGF3_ENST00000505655_chr4_738476_+_FANCI_ENST00000300027_chr15_89856135_+_1644nt CGGCAGAGGGACGGACACGCGGACGTCTAGCGGAGAAGCCAAAGATGTTGACCAGGAAGATCAAGCTGTGGGACATCAACGCCCACATCA CCTGCCGCCTGTGCAGCGGGTACCTCATCGACGCCACCACGGTGACCGAGTGTCTGCACACCTTCTGCAGGAGCTGCCTGGTGAAGTACC TGGAGGAGAACAACACCTGCCCCACCTGCAGGATTGTGATCCACCAGAGCCACCCCCTGCAGTACATCGGTCATGACAGAACCATGCAAG ATATTGTTTACAAATTGGTACCAGGCCTCCAAGAAGCGGAAATGAGAAAGCAGAGGGAGTTCTATCACAAATTGGGCATGGAGGTGCCGG GAGACATCAAGGGGGAGACCTGCTCTGCAAAACAGCACTTAGATTCCCATCGGAATGGTGAAACCAAAGCAGACGACAGTTCAAACAAAG AGGCCGCGGAGGAGAAGCCGGAGGAGGACAACGACTACCACCGCAGCGACGAGCAGAATAAGAGTAAGAGCCTGAACTATACGGGAGAGA AAAAGGAGAAACCTGCTGCCGTTGCCACAGCCATGGCCAGAGTTCTTCGGGAAACCAAGCCAATCCCTAACCTCATCTTTGCCATAGAAC AGTATGAAAAATTTCTCATCCACCTTTCTAAGAAGTCCAAGGTGAACCTGATGCAGCACATGAAGCTCAGCACCTCACGAGACTTCAAGA TCAAAGGAAACATCCTAGACATGGTTCTTCGAGAGGATGGTGAAGATGAAAATGAAGAGGGCACTGCATCAGAGCATGGGGGACAGAACA AAGAACCAGCCAAGAAGAAAAGGAAAAAATAAATGAAATGCCTGAGTTAATGTGAACTTTGGGGCTTCTGCTTCATTTTTACCCAACAAG CAACAATGCCCCTTGTCCTGTAGTCCACACCGATGTTGGCATCTTGGTTCTGAACCCACTGAATTCAACTGCACCTTCAGTTAGAAGGAA TCTTCTTGGCAGGTCCTGCTACTGAAAAATGGCTGGCCTTAGGCAAGCCCTTTTGCAAAAAGCACAGCTGAAAGCCTGAGTTTGGGAGCC TGCACCACCCCGATGAAGCTCCACGGGAGCAAATACAGAGCCTCCAGGCAGTGCTATGGTCCAGGCTGGCTTCGTTTTTCCAAGGAGCCT TTGGTGAGTTCAATTATCTGGTAAATATCCAGCGCTTCACCTGAAAGATAGTGCAAATTGGTTAGGATGCCACCTCAAGAACTGTAACTG AGAGCTCAGAAGTGAGCAAAGGAGCTTAATGCTAAGGTCAAAAGGAGAGTGAAAGGTTGAGAACAATTGCCACGAACGGTAATGTTACAT GTTAGGAGGGTCTGTTTTCTTTTTATATAAGTGTGTCTTAGATATATTTTAAATAGAAAATAAGCTTTCTGATTTACTTGTTTGGTATTT AAAGCACAGTTTGTTTTTCTGTCACCTATAGAGTGCAAGAATGCACTCTATAGAATAAATTATCTTTAAACATTTCTTCTGTGGTTGAAG TAGGGGACAGGTACAGGTAGAATATTTGAAGCTCTGCTGCCTTCATTTCTGAAACATCATATCACATTCACTCTGGACACAGGGCACCTT >In-frame_PCGF3_ENST00000505655_chr4_738476_+_FANCI_ENST00000310775_chr15_89856135_+_1512nt CGGCAGAGGGACGGACACGCGGACGTCTAGCGGAGAAGCCAAAGATGTTGACCAGGAAGATCAAGCTGTGGGACATCAACGCCCACATCA CCTGCCGCCTGTGCAGCGGGTACCTCATCGACGCCACCACGGTGACCGAGTGTCTGCACACCTTCTGCAGGAGCTGCCTGGTGAAGTACC TGGAGGAGAACAACACCTGCCCCACCTGCAGGATTGTGATCCACCAGAGCCACCCCCTGCAGTACATCGGTCATGACAGAACCATGCAAG ATATTGTTTACAAATTGGTACCAGGCCTCCAAGAAGCGGAAATGAGAAAGCAGAGGGAGTTCTATCACAAATTGGGCATGGAGGTGCCGG GAGACATCAAGGGGGAGACCTGCTCTGCAAAACAGCACTTAGATTCCCATCGGAATGGTGAAACCAAAGCAGACGACAGTTCAAACAAAG AGGCCGCGGAGGAGAAGCCGGAGGAGGACAACGACTACCACCGCAGCGACGAGCAGAATAAGAGTAAGAGCCTGAACTATACGGGAGAGA AAAAGGAGAAACCTGCTGCCGTTGCCACAGCCATGGCCAGAGTTCTTCGGGAAACCAAGCCAATCCCTAACCTCATCTTTGCCATAGAAC AGTATGAAAAATTTCTCATCCACCTTTCTAAGAAGTCCAAGGTGAACCTGATGCAGCACATGAAGCTCAGCACCTCACGAGACTTCAAGA TCAAAGGAAACATCCTAGACATGGTTCTTCGAGAGGATGGTGAAGATGAAAATGAAGAGGGCACTGCATCAGAGCATGGGGGACAGAACA AAGAACCAGCCAAGAAGAAAAGGAAAAAATAAATGAAATGCCTGAGTTAATGTGAACTTTGGGGCTTCTGCTTCATTTTTACCCAACAAG CAACAATGCCCCTTGTCCTGTAGTCCACACCGATGTTGGCATCTTGGTTCTGAACCCACTGAATTCAACTGCACCTTCAGTTAGAAGGAA TCTTCTTGGCAGGTCCTGCTACTGAAAAATGGCTGGCCTTAGGCAAGCCCTTTTGCAAAAAGCACAGCTGAAAGCCTGAGTTTGGGAGCC TGCACCACCCCGATGAAGCTCCACGGGAGCAAATACAGAGCCTCCAGGCAGTGCTATGGTCCAGGCTGGCTTCGTTTTTCCAAGGAGCCT TTGGTGAGTTCAATTATCTGGTAAATATCCAGCGCTTCACCTGAAAGATAGTGCAAATTGGTTAGGATGCCACCTCAAGAACTGTAACTG AGAGCTCAGAAGTGAGCAAAGGAGCTTAATGCTAAGGTCAAAAGGAGAGTGAAAGGTTGAGAACAATTGCCACGAACGGTAATGTTACAT GTTAGGAGGGTCTGTTTTCTTTTTATATAAGTGTGTCTTAGATATATTTTAAATAGAAAATAAGCTTTCTGATTTACTTGTTTGGTATTT |
Top |
FusionGenePPI for PCGF3_FANCI |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| PCGF3 | RNF2, RING1, RYBP, YAF2, CBX4, MGA, BCORL1, KDM2B, USP7, AUTS2, FBRS, FBRSL1, CSNK2A1, CSNK2A2, CSNK2B, HSP90AA1, CBX8, CBX7, CBX6, BCOR, BMI1, TRIM9, DZIP3, UBE2C, PHC2, PCGF3, UBE2D3, DCAF7, UBE2E3, KIAA0430, HELZ, CREBBP, EIF4ENIF1, ARID3A, SOWAHA, PAN2, NISCH, RB1, TRIM25 | FANCI | PTP4A3, ILK, C20orf24, PELO, GSTK1, NEK6, MAGED1, BRF2, MYC, USP36, ATM, CAMKK2, CLN3, PRKAB2, RAD18, FAN1, POLN, FANCD2, WDR48, PIDD1, SIRT7, FANCL, CUL3, APP, VCP, MMS19, HBS1L, PTPLAD1, EMD, MOV10, NXF1, ABCE1, IMPDH2, NTRK1, CEP120, DDOST, STXBP2, PAPSS1, CIR1, DGCR8, IMPACT, PRR3, DPY30, PLEKHA8, C1orf86, TIMM23, REV1, SNW1, CDC5L, POU5F1, PPM1A, RUNX3, UBL5, FANCI, MCM2, MCM3, MCM5, HELQ, FANCM, MTNR1B, PHLPP1, AKT1, PHLPP2, ATR, BRCA2, TRIM25, UHRF2 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for PCGF3_FANCI |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for PCGF3_FANCI |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | FANCI | C1836861 | FANCONI ANEMIA, COMPLEMENTATION GROUP I | 2 | CTD_human;UNIPROT |
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