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Fusion gene ID: 26186 |
FusionGeneSummary for PCDH10_UBAP1 |
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Fusion gene information | Fusion gene name: PCDH10_UBAP1 | Fusion gene ID: 26186 | Hgene | Tgene | Gene symbol | PCDH10 | UBAP1 | Gene ID | 57575 | 51271 |
Gene name | protocadherin 10 | ubiquitin associated protein 1 | |
Synonyms | OL-PCDH|PCDH19 | NAG20|UAP|UBAP|UBAP-1 | |
Cytomap | 4q28.3 | 9p13.3 | |
Type of gene | protein-coding | protein-coding | |
Description | protocadherin-10 | ubiquitin-associated protein 1nasopharyngeal carcinoma-associated gene 20 protein | |
Modification date | 20180523 | 20180523 | |
UniProtAcc | Q9P2E7 | Q9NZ09 | |
Ensembl transtripts involved in fusion gene | ENST00000264360, | ENST00000536252, ENST00000545103, ENST00000540348, ENST00000543944, ENST00000297661, ENST00000379186, ENST00000359544, | |
Fusion gene scores | * DoF score | 3 X 3 X 1=9 | 8 X 8 X 4=256 |
# samples | 3 | 9 | |
** MAII score | log2(3/9*10)=1.73696559416621 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(9/256*10)=-1.50814690367033 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
Context | PubMed: PCDH10 [Title/Abstract] AND UBAP1 [Title/Abstract] AND fusion [Title/Abstract] | ||
Functional or gene categories assigned by FusionGDB annotation |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
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Partner | Gene | GO ID | GO term | PubMed ID |
![]() (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChiTaRS3.1 | BF516551 | PCDH10 | chr4 | 134106541 | - | UBAP1 | chr9 | 34179972 | - |
* LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
intron-intron | ENST00000264360 | ENST00000536252 | PCDH10 | chr4 | 134106541 | - | UBAP1 | chr9 | 34179972 | - |
intron-intron | ENST00000264360 | ENST00000545103 | PCDH10 | chr4 | 134106541 | - | UBAP1 | chr9 | 34179972 | - |
intron-intron | ENST00000264360 | ENST00000540348 | PCDH10 | chr4 | 134106541 | - | UBAP1 | chr9 | 34179972 | - |
intron-intron | ENST00000264360 | ENST00000543944 | PCDH10 | chr4 | 134106541 | - | UBAP1 | chr9 | 34179972 | - |
intron-intron | ENST00000264360 | ENST00000297661 | PCDH10 | chr4 | 134106541 | - | UBAP1 | chr9 | 34179972 | - |
intron-intron | ENST00000264360 | ENST00000379186 | PCDH10 | chr4 | 134106541 | - | UBAP1 | chr9 | 34179972 | - |
intron-intron | ENST00000264360 | ENST00000359544 | PCDH10 | chr4 | 134106541 | - | UBAP1 | chr9 | 34179972 | - |
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FusionProtFeatures for PCDH10_UBAP1 |
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Hgene | Tgene |
PCDH10 | UBAP1 |
Potential calcium-dependent cell-adhesion protein. |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for PCDH10_UBAP1 |
![]() (nt: nucleotides, aa: amino acids) |
* Fusion amino acid sequences. |
* Fusion transcript sequences (only coding sequence (CDS) region). |
* Fusion transcript sequences (Full-length transcript). |
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FusionGenePPI for PCDH10_UBAP1 |
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Hgene | Hgene's interactors | Tgene | Tgene's interactors |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for PCDH10_UBAP1 |
![]() (DrugBank Version 5.1.0 2018-04-02) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for PCDH10_UBAP1 |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Hgene | PCDH10 | C0001973 | Alcoholic Intoxication, Chronic | 1 | PSYGENET |
Hgene | PCDH10 | C0004352 | Autistic Disorder | 1 | CTD_human |