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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDiseases

Fusion gene ID: 26112

FusionGeneSummary for PBRM1_WDR82

check button Fusion gene summary
Fusion gene informationFusion gene name: PBRM1_WDR82
Fusion gene ID: 26112
HgeneTgene
Gene symbol

PBRM1

WDR82

Gene ID

55193

80335

Gene namepolybromo 1WD repeat domain 82
SynonymsBAF180|PB1MST107|MSTP107|PRO2730|PRO34047|SWD2|TMEM113|WDR82A
Cytomap

3p21.1

3p21.2

Type of geneprotein-codingprotein-coding
Descriptionprotein polybromo-1BRG1-associated factor 180polybromo-1DWD repeat-containing protein 82transmembrane protein 113
Modification date2018052320180523
UniProtAcc

Q86U86

Q6UXN9

Ensembl transtripts involved in fusion geneENST00000356770, ENST00000394830, 
ENST00000296302, ENST00000337303, 
ENST00000410007, ENST00000409057, 
ENST00000409114, ENST00000409767, 
ENST00000296490, 
Fusion gene scores* DoF score9 X 6 X 9=4863 X 4 X 4=48
# samples 104
** MAII scorelog2(10/486*10)=-2.28095631383106
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/48*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PBRM1 [Title/Abstract] AND WDR82 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationTumor suppressor gene involved fusion gene, in-frame but not retained their domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneWDR82

GO:0051568

histone H3-K4 methylation

17355966


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDSTADTCGA-VQ-A928-01APBRM1chr3

52712516

-WDR82chr3

52304825

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000356770ENST00000296490PBRM1chr3

52712516

-WDR82chr3

52304825

-
Frame-shiftENST00000394830ENST00000296490PBRM1chr3

52712516

-WDR82chr3

52304825

-
In-frameENST00000296302ENST00000296490PBRM1chr3

52712516

-WDR82chr3

52304825

-
In-frameENST00000337303ENST00000296490PBRM1chr3

52712516

-WDR82chr3

52304825

-
In-frameENST00000410007ENST00000296490PBRM1chr3

52712516

-WDR82chr3

52304825

-
In-frameENST00000409057ENST00000296490PBRM1chr3

52712516

-WDR82chr3

52304825

-
In-frameENST00000409114ENST00000296490PBRM1chr3

52712516

-WDR82chr3

52304825

-
In-frameENST00000409767ENST00000296490PBRM1chr3

52712516

-WDR82chr3

52304825

-

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FusionProtFeatures for PBRM1_WDR82


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
PBRM1

Q86U86

WDR82

Q6UXN9

Regulatory component of the SET1 complex implicated inthe tethering of this complex to transcriptional start sites ofactive genes. Facilitates histone H3 'Lys-4' methylation viarecruitment of the SETD1A or SETD1B to the 'Ser-5' phosphorylatedC-terminal domain (CTD) of RNA polymerase II large subunit(POLR2A). Component of PTW/PP1 phosphatase complex, which plays arole in the control of chromatin structure and cell cycleprogression during the transition from mitosis into interphase.{ECO:0000269|PubMed:17998332, ECO:0000269|PubMed:18838538,ECO:0000269|PubMed:20516061}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneWDR82chr3:52712516chr3:52304825ENST00000296490-09105_14453314RepeatNote=WD 2
TgeneWDR82chr3:52712516chr3:52304825ENST00000296490-09146_18453314RepeatNote=WD 3
TgeneWDR82chr3:52712516chr3:52304825ENST00000296490-09192_23153314RepeatNote=WD 4
TgeneWDR82chr3:52712516chr3:52304825ENST00000296490-09236_27653314RepeatNote=WD 5
TgeneWDR82chr3:52712516chr3:52304825ENST00000296490-09280_31353314RepeatNote=WD 6

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePBRM1chr3:52712516chr3:52304825ENST00000296302-2301468_1599781690Compositional biasNote=Pro-rich
HgenePBRM1chr3:52712516chr3:52304825ENST00000296302-230630_633781690Compositional biasNote=Poly-Asp
HgenePBRM1chr3:52712516chr3:52304825ENST00000337303-2281468_1599781583Compositional biasNote=Pro-rich
HgenePBRM1chr3:52712516chr3:52304825ENST00000337303-228630_633781583Compositional biasNote=Poly-Asp
HgenePBRM1chr3:52712516chr3:52304825ENST00000356770-2281468_1599781603Compositional biasNote=Pro-rich
HgenePBRM1chr3:52712516chr3:52304825ENST00000356770-228630_633781603Compositional biasNote=Poly-Asp
HgenePBRM1chr3:52712516chr3:52304825ENST00000394830-3301468_1599781583Compositional biasNote=Pro-rich
HgenePBRM1chr3:52712516chr3:52304825ENST00000394830-330630_633781583Compositional biasNote=Poly-Asp
HgenePBRM1chr3:52712516chr3:52304825ENST00000409057-2291468_1599781635Compositional biasNote=Pro-rich
HgenePBRM1chr3:52712516chr3:52304825ENST00000409057-229630_633781635Compositional biasNote=Poly-Asp
HgenePBRM1chr3:52712516chr3:52304825ENST00000409114-2301468_1599781653Compositional biasNote=Pro-rich
HgenePBRM1chr3:52712516chr3:52304825ENST00000409114-230630_633781653Compositional biasNote=Poly-Asp
HgenePBRM1chr3:52712516chr3:52304825ENST00000409767-2291468_1599781598Compositional biasNote=Pro-rich
HgenePBRM1chr3:52712516chr3:52304825ENST00000409767-229630_633781598Compositional biasNote=Poly-Asp
HgenePBRM1chr3:52712516chr3:52304825ENST00000410007-2291468_1599781610Compositional biasNote=Pro-rich
HgenePBRM1chr3:52712516chr3:52304825ENST00000410007-229630_633781610Compositional biasNote=Poly-Asp
HgenePBRM1chr3:52712516chr3:52304825ENST00000296302-2301379_1447781690DNA bindingHMG box
HgenePBRM1chr3:52712516chr3:52304825ENST00000337303-2281379_1447781583DNA bindingHMG box
HgenePBRM1chr3:52712516chr3:52304825ENST00000356770-2281379_1447781603DNA bindingHMG box
HgenePBRM1chr3:52712516chr3:52304825ENST00000394830-3301379_1447781583DNA bindingHMG box
HgenePBRM1chr3:52712516chr3:52304825ENST00000409057-2291379_1447781635DNA bindingHMG box
HgenePBRM1chr3:52712516chr3:52304825ENST00000409114-2301379_1447781653DNA bindingHMG box
HgenePBRM1chr3:52712516chr3:52304825ENST00000409767-2291379_1447781598DNA bindingHMG box
HgenePBRM1chr3:52712516chr3:52304825ENST00000410007-2291379_1447781610DNA bindingHMG box
HgenePBRM1chr3:52712516chr3:52304825ENST00000296302-2301156_1272781690DomainBAH 2
HgenePBRM1chr3:52712516chr3:52304825ENST00000296302-230200_270781690DomainBromo 2
HgenePBRM1chr3:52712516chr3:52304825ENST00000296302-230400_470781690DomainBromo 3
HgenePBRM1chr3:52712516chr3:52304825ENST00000296302-230538_608781690DomainBromo 4
HgenePBRM1chr3:52712516chr3:52304825ENST00000296302-23064_134781690DomainBromo 1
HgenePBRM1chr3:52712516chr3:52304825ENST00000296302-230676_746781690DomainBromo 5
HgenePBRM1chr3:52712516chr3:52304825ENST00000296302-230792_862781690DomainBromo 6
HgenePBRM1chr3:52712516chr3:52304825ENST00000296302-230956_1074781690DomainBAH 1
HgenePBRM1chr3:52712516chr3:52304825ENST00000337303-2281156_1272781583DomainBAH 2
HgenePBRM1chr3:52712516chr3:52304825ENST00000337303-228200_270781583DomainBromo 2
HgenePBRM1chr3:52712516chr3:52304825ENST00000337303-228400_470781583DomainBromo 3
HgenePBRM1chr3:52712516chr3:52304825ENST00000337303-228538_608781583DomainBromo 4
HgenePBRM1chr3:52712516chr3:52304825ENST00000337303-22864_134781583DomainBromo 1
HgenePBRM1chr3:52712516chr3:52304825ENST00000337303-228676_746781583DomainBromo 5
HgenePBRM1chr3:52712516chr3:52304825ENST00000337303-228792_862781583DomainBromo 6
HgenePBRM1chr3:52712516chr3:52304825ENST00000337303-228956_1074781583DomainBAH 1
HgenePBRM1chr3:52712516chr3:52304825ENST00000356770-2281156_1272781603DomainBAH 2
HgenePBRM1chr3:52712516chr3:52304825ENST00000356770-228200_270781603DomainBromo 2
HgenePBRM1chr3:52712516chr3:52304825ENST00000356770-228400_470781603DomainBromo 3
HgenePBRM1chr3:52712516chr3:52304825ENST00000356770-228538_608781603DomainBromo 4
HgenePBRM1chr3:52712516chr3:52304825ENST00000356770-22864_134781603DomainBromo 1
HgenePBRM1chr3:52712516chr3:52304825ENST00000356770-228676_746781603DomainBromo 5
HgenePBRM1chr3:52712516chr3:52304825ENST00000356770-228792_862781603DomainBromo 6
HgenePBRM1chr3:52712516chr3:52304825ENST00000356770-228956_1074781603DomainBAH 1
HgenePBRM1chr3:52712516chr3:52304825ENST00000394830-3301156_1272781583DomainBAH 2
HgenePBRM1chr3:52712516chr3:52304825ENST00000394830-330200_270781583DomainBromo 2
HgenePBRM1chr3:52712516chr3:52304825ENST00000394830-330400_470781583DomainBromo 3
HgenePBRM1chr3:52712516chr3:52304825ENST00000394830-330538_608781583DomainBromo 4
HgenePBRM1chr3:52712516chr3:52304825ENST00000394830-33064_134781583DomainBromo 1
HgenePBRM1chr3:52712516chr3:52304825ENST00000394830-330676_746781583DomainBromo 5
HgenePBRM1chr3:52712516chr3:52304825ENST00000394830-330792_862781583DomainBromo 6
HgenePBRM1chr3:52712516chr3:52304825ENST00000394830-330956_1074781583DomainBAH 1
HgenePBRM1chr3:52712516chr3:52304825ENST00000409057-2291156_1272781635DomainBAH 2
HgenePBRM1chr3:52712516chr3:52304825ENST00000409057-229200_270781635DomainBromo 2
HgenePBRM1chr3:52712516chr3:52304825ENST00000409057-229400_470781635DomainBromo 3
HgenePBRM1chr3:52712516chr3:52304825ENST00000409057-229538_608781635DomainBromo 4
HgenePBRM1chr3:52712516chr3:52304825ENST00000409057-22964_134781635DomainBromo 1
HgenePBRM1chr3:52712516chr3:52304825ENST00000409057-229676_746781635DomainBromo 5
HgenePBRM1chr3:52712516chr3:52304825ENST00000409057-229792_862781635DomainBromo 6
HgenePBRM1chr3:52712516chr3:52304825ENST00000409057-229956_1074781635DomainBAH 1
HgenePBRM1chr3:52712516chr3:52304825ENST00000409114-2301156_1272781653DomainBAH 2
HgenePBRM1chr3:52712516chr3:52304825ENST00000409114-230200_270781653DomainBromo 2
HgenePBRM1chr3:52712516chr3:52304825ENST00000409114-230400_470781653DomainBromo 3
HgenePBRM1chr3:52712516chr3:52304825ENST00000409114-230538_608781653DomainBromo 4
HgenePBRM1chr3:52712516chr3:52304825ENST00000409114-23064_134781653DomainBromo 1
HgenePBRM1chr3:52712516chr3:52304825ENST00000409114-230676_746781653DomainBromo 5
HgenePBRM1chr3:52712516chr3:52304825ENST00000409114-230792_862781653DomainBromo 6
HgenePBRM1chr3:52712516chr3:52304825ENST00000409114-230956_1074781653DomainBAH 1
HgenePBRM1chr3:52712516chr3:52304825ENST00000409767-2291156_1272781598DomainBAH 2
HgenePBRM1chr3:52712516chr3:52304825ENST00000409767-229200_270781598DomainBromo 2
HgenePBRM1chr3:52712516chr3:52304825ENST00000409767-229400_470781598DomainBromo 3
HgenePBRM1chr3:52712516chr3:52304825ENST00000409767-229538_608781598DomainBromo 4
HgenePBRM1chr3:52712516chr3:52304825ENST00000409767-22964_134781598DomainBromo 1
HgenePBRM1chr3:52712516chr3:52304825ENST00000409767-229676_746781598DomainBromo 5
HgenePBRM1chr3:52712516chr3:52304825ENST00000409767-229792_862781598DomainBromo 6
HgenePBRM1chr3:52712516chr3:52304825ENST00000409767-229956_1074781598DomainBAH 1
HgenePBRM1chr3:52712516chr3:52304825ENST00000410007-2291156_1272781610DomainBAH 2
HgenePBRM1chr3:52712516chr3:52304825ENST00000410007-229200_270781610DomainBromo 2
HgenePBRM1chr3:52712516chr3:52304825ENST00000410007-229400_470781610DomainBromo 3
HgenePBRM1chr3:52712516chr3:52304825ENST00000410007-229538_608781610DomainBromo 4
HgenePBRM1chr3:52712516chr3:52304825ENST00000410007-22964_134781610DomainBromo 1
HgenePBRM1chr3:52712516chr3:52304825ENST00000410007-229676_746781610DomainBromo 5
HgenePBRM1chr3:52712516chr3:52304825ENST00000410007-229792_862781610DomainBromo 6
HgenePBRM1chr3:52712516chr3:52304825ENST00000410007-229956_1074781610DomainBAH 1
TgeneWDR82chr3:52712516chr3:52304825ENST00000296490-0919_5853314RepeatNote=WD 1


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FusionGeneSequence for PBRM1_WDR82


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_PBRM1_ENST00000356770_chr3_52712516_-_WDR82_ENST00000296490_chr3_52304825_-_339aa
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRPKRTLYSKKYG
VDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWDLRSPNCQGLMHLQGKPVCSF
DPEGLIFAAGVNSEMVKLYDLRSFDKGPFATFKMQYDRTCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEA

>In-frame_PBRM1_ENST00000296302_chr3_52712516_-_WDR82_ENST00000296490_chr3_52304825_-_339aa
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRPKRTLYSKKYG
VDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWDLRSPNCQGLMHLQGKPVCSF
DPEGLIFAAGVNSEMVKLYDLRSFDKGPFATFKMQYDRTCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEA

>In-frame_PBRM1_ENST00000337303_chr3_52712516_-_WDR82_ENST00000296490_chr3_52304825_-_339aa
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRPKRTLYSKKYG
VDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWDLRSPNCQGLMHLQGKPVCSF
DPEGLIFAAGVNSEMVKLYDLRSFDKGPFATFKMQYDRTCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEA

>In-frame_PBRM1_ENST00000410007_chr3_52712516_-_WDR82_ENST00000296490_chr3_52304825_-_339aa
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRPKRTLYSKKYG
VDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWDLRSPNCQGLMHLQGKPVCSF
DPEGLIFAAGVNSEMVKLYDLRSFDKGPFATFKMQYDRTCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEA

>In-frame_PBRM1_ENST00000409057_chr3_52712516_-_WDR82_ENST00000296490_chr3_52304825_-_339aa
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRPKRTLYSKKYG
VDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWDLRSPNCQGLMHLQGKPVCSF
DPEGLIFAAGVNSEMVKLYDLRSFDKGPFATFKMQYDRTCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEA

>In-frame_PBRM1_ENST00000409114_chr3_52712516_-_WDR82_ENST00000296490_chr3_52304825_-_339aa
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRPKRTLYSKKYG
VDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWDLRSPNCQGLMHLQGKPVCSF
DPEGLIFAAGVNSEMVKLYDLRSFDKGPFATFKMQYDRTCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEA

>In-frame_PBRM1_ENST00000409767_chr3_52712516_-_WDR82_ENST00000296490_chr3_52304825_-_339aa
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRPKRTLYSKKYG
VDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRYFPGHSKRVVALSMSPVDDTFISGSLDKTIRLWDLRSPNCQGLMHLQGKPVCSF
DPEGLIFAAGVNSEMVKLYDLRSFDKGPFATFKMQYDRTCEWTGLKFSNDGKLILISTNGSFIRLIDAFKGVVMHTFGGYANSKAVTLEA


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_PBRM1_ENST00000356770_chr3_52712516_-_WDR82_ENST00000296490_chr3_52304825_-_1017nt
ATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAGGC
CCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACTAT
AAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGACCAAAGAGAACCCTGTACAGTAAGAAATATGGT
GTGGACCTCATCAGATACACTCATGCAGCAAACACAGTTGTTTACAGCTCTAACAAAATAGACGATACTATTCGTTACTTGTCCTTGCAT
GACAACAAATACATCAGATACTTTCCTGGACATAGCAAAAGGGTGGTGGCCTTGTCCATGTCACCTGTGGATGACACTTTCATTTCTGGG
TCTCTTGATAAGACCATTCGACTCTGGGATCTCCGGTCTCCTAACTGCCAGGGCCTCATGCATCTGCAGGGGAAGCCAGTTTGTTCTTTT
GATCCAGAAGGGTTAATTTTCGCTGCAGGTGTCAACTCTGAAATGGTCAAGCTTTATGACCTTCGTTCTTTTGATAAGGGGCCATTTGCT
ACCTTTAAGATGCAGTATGATCGAACTTGTGAGTGGACAGGACTTAAATTCAGCAATGATGGCAAGCTCATCCTCATTTCCACCAACGGC
AGCTTCATTCGTCTGATTGATGCATTCAAAGGAGTGGTGATGCACACATTTGGGGGTTATGCCAACAGCAAAGCTGTCACACTGGAGGCT
TCATTTACTCCAGACTCTCAGTTTATTATGATTGGTTCAGAGGATGGCAAGATCCATGTCTGGAATGGAGAGAGCGGTATAAAAGTAGCT
GTGTTGGATGGTAAACACACAGGCCCGATTACCTGTTTGCAATTCAACCCCAAGTTCATGACTTTTGCCAGTGCGTGTTCCAACATGGCC

>In-frame_PBRM1_ENST00000296302_chr3_52712516_-_WDR82_ENST00000296490_chr3_52304825_-_1017nt
ATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAGGC
CCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACTAT
AAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGACCAAAGAGAACCCTGTACAGTAAGAAATATGGT
GTGGACCTCATCAGATACACTCATGCAGCAAACACAGTTGTTTACAGCTCTAACAAAATAGACGATACTATTCGTTACTTGTCCTTGCAT
GACAACAAATACATCAGATACTTTCCTGGACATAGCAAAAGGGTGGTGGCCTTGTCCATGTCACCTGTGGATGACACTTTCATTTCTGGG
TCTCTTGATAAGACCATTCGACTCTGGGATCTCCGGTCTCCTAACTGCCAGGGCCTCATGCATCTGCAGGGGAAGCCAGTTTGTTCTTTT
GATCCAGAAGGGTTAATTTTCGCTGCAGGTGTCAACTCTGAAATGGTCAAGCTTTATGACCTTCGTTCTTTTGATAAGGGGCCATTTGCT
ACCTTTAAGATGCAGTATGATCGAACTTGTGAGTGGACAGGACTTAAATTCAGCAATGATGGCAAGCTCATCCTCATTTCCACCAACGGC
AGCTTCATTCGTCTGATTGATGCATTCAAAGGAGTGGTGATGCACACATTTGGGGGTTATGCCAACAGCAAAGCTGTCACACTGGAGGCT
TCATTTACTCCAGACTCTCAGTTTATTATGATTGGTTCAGAGGATGGCAAGATCCATGTCTGGAATGGAGAGAGCGGTATAAAAGTAGCT
GTGTTGGATGGTAAACACACAGGCCCGATTACCTGTTTGCAATTCAACCCCAAGTTCATGACTTTTGCCAGTGCGTGTTCCAACATGGCC

>In-frame_PBRM1_ENST00000337303_chr3_52712516_-_WDR82_ENST00000296490_chr3_52304825_-_1017nt
ATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAGGC
CCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACTAT
AAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGACCAAAGAGAACCCTGTACAGTAAGAAATATGGT
GTGGACCTCATCAGATACACTCATGCAGCAAACACAGTTGTTTACAGCTCTAACAAAATAGACGATACTATTCGTTACTTGTCCTTGCAT
GACAACAAATACATCAGATACTTTCCTGGACATAGCAAAAGGGTGGTGGCCTTGTCCATGTCACCTGTGGATGACACTTTCATTTCTGGG
TCTCTTGATAAGACCATTCGACTCTGGGATCTCCGGTCTCCTAACTGCCAGGGCCTCATGCATCTGCAGGGGAAGCCAGTTTGTTCTTTT
GATCCAGAAGGGTTAATTTTCGCTGCAGGTGTCAACTCTGAAATGGTCAAGCTTTATGACCTTCGTTCTTTTGATAAGGGGCCATTTGCT
ACCTTTAAGATGCAGTATGATCGAACTTGTGAGTGGACAGGACTTAAATTCAGCAATGATGGCAAGCTCATCCTCATTTCCACCAACGGC
AGCTTCATTCGTCTGATTGATGCATTCAAAGGAGTGGTGATGCACACATTTGGGGGTTATGCCAACAGCAAAGCTGTCACACTGGAGGCT
TCATTTACTCCAGACTCTCAGTTTATTATGATTGGTTCAGAGGATGGCAAGATCCATGTCTGGAATGGAGAGAGCGGTATAAAAGTAGCT
GTGTTGGATGGTAAACACACAGGCCCGATTACCTGTTTGCAATTCAACCCCAAGTTCATGACTTTTGCCAGTGCGTGTTCCAACATGGCC

>In-frame_PBRM1_ENST00000410007_chr3_52712516_-_WDR82_ENST00000296490_chr3_52304825_-_1017nt
ATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAGGC
CCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACTAT
AAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGACCAAAGAGAACCCTGTACAGTAAGAAATATGGT
GTGGACCTCATCAGATACACTCATGCAGCAAACACAGTTGTTTACAGCTCTAACAAAATAGACGATACTATTCGTTACTTGTCCTTGCAT
GACAACAAATACATCAGATACTTTCCTGGACATAGCAAAAGGGTGGTGGCCTTGTCCATGTCACCTGTGGATGACACTTTCATTTCTGGG
TCTCTTGATAAGACCATTCGACTCTGGGATCTCCGGTCTCCTAACTGCCAGGGCCTCATGCATCTGCAGGGGAAGCCAGTTTGTTCTTTT
GATCCAGAAGGGTTAATTTTCGCTGCAGGTGTCAACTCTGAAATGGTCAAGCTTTATGACCTTCGTTCTTTTGATAAGGGGCCATTTGCT
ACCTTTAAGATGCAGTATGATCGAACTTGTGAGTGGACAGGACTTAAATTCAGCAATGATGGCAAGCTCATCCTCATTTCCACCAACGGC
AGCTTCATTCGTCTGATTGATGCATTCAAAGGAGTGGTGATGCACACATTTGGGGGTTATGCCAACAGCAAAGCTGTCACACTGGAGGCT
TCATTTACTCCAGACTCTCAGTTTATTATGATTGGTTCAGAGGATGGCAAGATCCATGTCTGGAATGGAGAGAGCGGTATAAAAGTAGCT
GTGTTGGATGGTAAACACACAGGCCCGATTACCTGTTTGCAATTCAACCCCAAGTTCATGACTTTTGCCAGTGCGTGTTCCAACATGGCC

>In-frame_PBRM1_ENST00000409057_chr3_52712516_-_WDR82_ENST00000296490_chr3_52304825_-_1017nt
ATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAGGC
CCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACTAT
AAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGACCAAAGAGAACCCTGTACAGTAAGAAATATGGT
GTGGACCTCATCAGATACACTCATGCAGCAAACACAGTTGTTTACAGCTCTAACAAAATAGACGATACTATTCGTTACTTGTCCTTGCAT
GACAACAAATACATCAGATACTTTCCTGGACATAGCAAAAGGGTGGTGGCCTTGTCCATGTCACCTGTGGATGACACTTTCATTTCTGGG
TCTCTTGATAAGACCATTCGACTCTGGGATCTCCGGTCTCCTAACTGCCAGGGCCTCATGCATCTGCAGGGGAAGCCAGTTTGTTCTTTT
GATCCAGAAGGGTTAATTTTCGCTGCAGGTGTCAACTCTGAAATGGTCAAGCTTTATGACCTTCGTTCTTTTGATAAGGGGCCATTTGCT
ACCTTTAAGATGCAGTATGATCGAACTTGTGAGTGGACAGGACTTAAATTCAGCAATGATGGCAAGCTCATCCTCATTTCCACCAACGGC
AGCTTCATTCGTCTGATTGATGCATTCAAAGGAGTGGTGATGCACACATTTGGGGGTTATGCCAACAGCAAAGCTGTCACACTGGAGGCT
TCATTTACTCCAGACTCTCAGTTTATTATGATTGGTTCAGAGGATGGCAAGATCCATGTCTGGAATGGAGAGAGCGGTATAAAAGTAGCT
GTGTTGGATGGTAAACACACAGGCCCGATTACCTGTTTGCAATTCAACCCCAAGTTCATGACTTTTGCCAGTGCGTGTTCCAACATGGCC

>In-frame_PBRM1_ENST00000409114_chr3_52712516_-_WDR82_ENST00000296490_chr3_52304825_-_1017nt
ATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAGGC
CCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACTAT
AAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGACCAAAGAGAACCCTGTACAGTAAGAAATATGGT
GTGGACCTCATCAGATACACTCATGCAGCAAACACAGTTGTTTACAGCTCTAACAAAATAGACGATACTATTCGTTACTTGTCCTTGCAT
GACAACAAATACATCAGATACTTTCCTGGACATAGCAAAAGGGTGGTGGCCTTGTCCATGTCACCTGTGGATGACACTTTCATTTCTGGG
TCTCTTGATAAGACCATTCGACTCTGGGATCTCCGGTCTCCTAACTGCCAGGGCCTCATGCATCTGCAGGGGAAGCCAGTTTGTTCTTTT
GATCCAGAAGGGTTAATTTTCGCTGCAGGTGTCAACTCTGAAATGGTCAAGCTTTATGACCTTCGTTCTTTTGATAAGGGGCCATTTGCT
ACCTTTAAGATGCAGTATGATCGAACTTGTGAGTGGACAGGACTTAAATTCAGCAATGATGGCAAGCTCATCCTCATTTCCACCAACGGC
AGCTTCATTCGTCTGATTGATGCATTCAAAGGAGTGGTGATGCACACATTTGGGGGTTATGCCAACAGCAAAGCTGTCACACTGGAGGCT
TCATTTACTCCAGACTCTCAGTTTATTATGATTGGTTCAGAGGATGGCAAGATCCATGTCTGGAATGGAGAGAGCGGTATAAAAGTAGCT
GTGTTGGATGGTAAACACACAGGCCCGATTACCTGTTTGCAATTCAACCCCAAGTTCATGACTTTTGCCAGTGCGTGTTCCAACATGGCC

>In-frame_PBRM1_ENST00000409767_chr3_52712516_-_WDR82_ENST00000296490_chr3_52304825_-_1017nt
ATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAGGC
CCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACTAT
AAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGACCAAAGAGAACCCTGTACAGTAAGAAATATGGT
GTGGACCTCATCAGATACACTCATGCAGCAAACACAGTTGTTTACAGCTCTAACAAAATAGACGATACTATTCGTTACTTGTCCTTGCAT
GACAACAAATACATCAGATACTTTCCTGGACATAGCAAAAGGGTGGTGGCCTTGTCCATGTCACCTGTGGATGACACTTTCATTTCTGGG
TCTCTTGATAAGACCATTCGACTCTGGGATCTCCGGTCTCCTAACTGCCAGGGCCTCATGCATCTGCAGGGGAAGCCAGTTTGTTCTTTT
GATCCAGAAGGGTTAATTTTCGCTGCAGGTGTCAACTCTGAAATGGTCAAGCTTTATGACCTTCGTTCTTTTGATAAGGGGCCATTTGCT
ACCTTTAAGATGCAGTATGATCGAACTTGTGAGTGGACAGGACTTAAATTCAGCAATGATGGCAAGCTCATCCTCATTTCCACCAACGGC
AGCTTCATTCGTCTGATTGATGCATTCAAAGGAGTGGTGATGCACACATTTGGGGGTTATGCCAACAGCAAAGCTGTCACACTGGAGGCT
TCATTTACTCCAGACTCTCAGTTTATTATGATTGGTTCAGAGGATGGCAAGATCCATGTCTGGAATGGAGAGAGCGGTATAAAAGTAGCT
GTGTTGGATGGTAAACACACAGGCCCGATTACCTGTTTGCAATTCAACCCCAAGTTCATGACTTTTGCCAGTGCGTGTTCCAACATGGCC


* Fusion transcript sequences (Full-length transcript).
>In-frame_PBRM1_ENST00000356770_chr3_52712516_-_WDR82_ENST00000296490_chr3_52304825_-_4089nt
TCCATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCA
GGCCCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGAC
TATAAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGACCAAAGAGAACCCTGTACAGTAAGAAATAT
GGTGTGGACCTCATCAGATACACTCATGCAGCAAACACAGTTGTTTACAGCTCTAACAAAATAGACGATACTATTCGTTACTTGTCCTTG
CATGACAACAAATACATCAGATACTTTCCTGGACATAGCAAAAGGGTGGTGGCCTTGTCCATGTCACCTGTGGATGACACTTTCATTTCT
GGGTCTCTTGATAAGACCATTCGACTCTGGGATCTCCGGTCTCCTAACTGCCAGGGCCTCATGCATCTGCAGGGGAAGCCAGTTTGTTCT
TTTGATCCAGAAGGGTTAATTTTCGCTGCAGGTGTCAACTCTGAAATGGTCAAGCTTTATGACCTTCGTTCTTTTGATAAGGGGCCATTT
GCTACCTTTAAGATGCAGTATGATCGAACTTGTGAGTGGACAGGACTTAAATTCAGCAATGATGGCAAGCTCATCCTCATTTCCACCAAC
GGCAGCTTCATTCGTCTGATTGATGCATTCAAAGGAGTGGTGATGCACACATTTGGGGGTTATGCCAACAGCAAAGCTGTCACACTGGAG
GCTTCATTTACTCCAGACTCTCAGTTTATTATGATTGGTTCAGAGGATGGCAAGATCCATGTCTGGAATGGAGAGAGCGGTATAAAAGTA
GCTGTGTTGGATGGTAAACACACAGGCCCGATTACCTGTTTGCAATTCAACCCCAAGTTCATGACTTTTGCCAGTGCGTGTTCCAACATG
GCCTTTTGGTTGCCCACCATTGATGACTGACCCTGTTGCTGCTTGGCTATTTCTGTATAGTGAGGGCGGCCAGCAGGAAGAAACTCAGAG
GGAACTGAGATAATAGTGGGATTGGATCATTTGACTGGGCTGGAGAACATCCTTTTACATGGCCTTCCCATGGATGTGCTGTACATCTGC
TCAAAAGAAAATAATTACTTTGATGAGCGTCTTCAAAAGGACTCTTGGTGCAACAGACTCAATTGGAACTCAGCTTTTCTAACTGTCACT
GCACCAAGCTCTGCTGGAGGAGTGACCAGACTCACGATTTGGTATAGTGGGGCTCTCAAGCATCTTCAATTTGAATGTACATGCTGCTGA
GGAGCCGGTGAAGTCATCAGTTCCGCACATCCCTTCTACCCTCCAACTGCATGGGAAGCCAAAGTCCTGGTTTTGAAATGCTTGGGCAGC
TCAGCCGCTTGCCCTCACCCTGCATGTCTTGTTACTGGGTCTCCCTGTGTACTTGTGGCATTATCCACAACCATCATGTTTCTTAGGTGC
CAAACATTTACAGAAACATTTTCATATATCTTGGGGTCAGAGAAAGGGACAGATACAGAAGGACCTTGCTTGCAGGAAGCCATGCAGTTA
GTTTCTGCAGTTAGTCGTGTGAGGCTAGGTGGTTGGGCAGGCCTCGGGCTGTAGGTGTTGGGTGGGAAAAAGACCCAAGGGCCTGAAAGG
GAGGGAAAGGGGAGGGTAGCGGGAGGGTAGCAGGTGAGTTCCTAGGGCTGGAAGGTTTAGCAGCAGCCTGGTGCAGTGCCCTGTCATCAA
GACAAACCCACGGTCCTCCTGGGTGCCTACCAAGCTTGGTTTGTACAAAAGCAAGGTGGGAGTCTATTTTTGTACATGAGATACATCACA
CTTACCTGTGGGCCAGTATTGTGAAGTGAGTCTGAGTTGTTTACACTGATGCCTTCCCTGCCCACCACAAATTGTGTACATAGTCTTCAG
ATGATACCACCCCTTTCCCCAGCTCCCAACCAAGAGCTGGTTCTAGGCCTGTGTTATATGTCATATTTAGCGTTTTTATATATGACCTTT
GATTTCTGTTGTTTGTATTTTAGCACAGTGTATGCACCTTCATTTAAATACATCTGTGTGCATACAGATACGCATATATGTGTGTGCGTA
TGCATATATCTCTCATCTGTAGTTTCCAAGAGTTCAGCTGAAGCAGATGGAGTCCTGCAGCCCAGGAGACACCCTGCATCCCTGCTAATA
GTGTTTGCCACAAGTATTAGTGAGTCTTCCTTATTAATATTTTCATTTCAGAAGACTGAAGCAAAGCTGATAGTGTTTGCTGTTTCTTTG
GCAGCTAAGTGAGGGTCTTGGGATGACTTGCTGTGTTCCTCAAGCTGCACTTTGGGGCCATCTCTGCAGTATTAGCCCCCTTTTTGCTTG
GTGGTACTCTGTCTGTGCCTGTGTGTGTGTGTGATAGTCACTCTTGCATGGCTTCCATGTCTGGTTTGTGGCATTTGGGGATAAGGTGCT
GAAGCCAGAGCATTTGCAGTTTGTTTGAGGCCTCGTTGCCAATGATAGATCACTCCTGTTGACCTGGTATGTCTGCTTGCTTGCTGCTTT
TCCTTGCTTTCTCTTGGAAGAGGAAAGGACTCTGGTCAGGCCCAGGCTGAGTGAGATGAGCTGCAGCTGGCTCATGGCCTTCTTAGAGCA
GAGAGAGGAGTATGTCATTTTACTAAGTTCCTAAACAAACATTTATGCAGGCAACACTCCTTGCAGATCCAGAAACTGAGGCACAATAGG
GTTATGACTTGCTCAAGAATATGTAGCTGCTAGGGGGTAAATCAAGGCATCACAATTTCTGTTCAGCGGGCAGGAATAGGCTGTGAATTG
CTAGCACTTTTTTTTTTTAAGCAATTACTTTTTGACTTGTTCCTCTGAAAGTGCAAGAGGCGTACACCTTTCCCAAATGTAGACTAGAAT
CTGCAGGATGCCACCCACTGTATAGTTCTGCTTTCCCAGAGAGGAAGAACTTTTAGAAACCAAATGATCTTAATTGTTATTGCCCACCCC
TGGCTTTTCCGGGTAGAAAATTCACAGTAGGAATGATTGTTAAGAGAGAGTGCTTGGAACCATGGGTTAACAGGAAAGGCTACCTAACTT
CACATATCTGCAACCAGAGCAGCCACCAAGCATTACTTAGCAGCAGGAAAATGATTGTATTTGAGTTCCTGTGTGTCCAAAACTGAGCAC
CATGTTCTTTGAAAACATGCCACCTCAAGGCTGGGCGCGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATC
ACCGGAGGTCGGGAGTTTGAGACCAGCCTGACCAACATGGAGAAACCCCATCTCTACTAAAAATACAAAATTAGCCGGGCGTGGTGGCAT
GCGCCTATAATCTCAGCTACTTGGGAGGCTGAGGCAGGAGAATTGCTTGAACCCAGGAGGCGGAGGTTGCGGTGAGTTGAGATCGTGCCA
TTGCACTCCGGCCTGGGCAACAACAGCAAAACTCCGTCTCAAAAAAAAAAAAAAAAAAATGCCACCTCACAGTCTCTATCGTTGGGCCCT
GTGGTTGCAAAGCTGCCTCCTGAATTAAGAAGGAAAGGGAAAAGATATAGCTGGAAGCGAGTGGAAGAGATGCTGAGGGCTGGGGCTGCA
CAGACGTGCTCAGCAGGGCTACAGGTGCTCAAGCCCTATTGGGGATGGGTGGGGAGTGGGGCAGCGGCGTTTGCCACCTTAAGAATTGGG
GCCAAAGCCACTGATGTTTATTTGACAGTGACACTGCACTGGGTACTTAAAGAAATTATTTCCCGTTGTAATTATAATTACTGCTTATTA
AGGAAAATATGGGAATTTTAGAAAGAATCAAGTTTGCCACCCAAATGCTACCACTGTTAATCTTTTGGTGTTAAATGTTCCCCCTAGACA
TTTCTGTGCATAGATTTTTGGTGTGTTTACATAGTCGTTATTCTGTATATACAATTTTATGTCCCTTTTGTACTTAACGTATAAACATTT

>In-frame_PBRM1_ENST00000296302_chr3_52712516_-_WDR82_ENST00000296490_chr3_52304825_-_4088nt
CCATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAG
GCCCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACT
ATAAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGACCAAAGAGAACCCTGTACAGTAAGAAATATG
GTGTGGACCTCATCAGATACACTCATGCAGCAAACACAGTTGTTTACAGCTCTAACAAAATAGACGATACTATTCGTTACTTGTCCTTGC
ATGACAACAAATACATCAGATACTTTCCTGGACATAGCAAAAGGGTGGTGGCCTTGTCCATGTCACCTGTGGATGACACTTTCATTTCTG
GGTCTCTTGATAAGACCATTCGACTCTGGGATCTCCGGTCTCCTAACTGCCAGGGCCTCATGCATCTGCAGGGGAAGCCAGTTTGTTCTT
TTGATCCAGAAGGGTTAATTTTCGCTGCAGGTGTCAACTCTGAAATGGTCAAGCTTTATGACCTTCGTTCTTTTGATAAGGGGCCATTTG
CTACCTTTAAGATGCAGTATGATCGAACTTGTGAGTGGACAGGACTTAAATTCAGCAATGATGGCAAGCTCATCCTCATTTCCACCAACG
GCAGCTTCATTCGTCTGATTGATGCATTCAAAGGAGTGGTGATGCACACATTTGGGGGTTATGCCAACAGCAAAGCTGTCACACTGGAGG
CTTCATTTACTCCAGACTCTCAGTTTATTATGATTGGTTCAGAGGATGGCAAGATCCATGTCTGGAATGGAGAGAGCGGTATAAAAGTAG
CTGTGTTGGATGGTAAACACACAGGCCCGATTACCTGTTTGCAATTCAACCCCAAGTTCATGACTTTTGCCAGTGCGTGTTCCAACATGG
CCTTTTGGTTGCCCACCATTGATGACTGACCCTGTTGCTGCTTGGCTATTTCTGTATAGTGAGGGCGGCCAGCAGGAAGAAACTCAGAGG
GAACTGAGATAATAGTGGGATTGGATCATTTGACTGGGCTGGAGAACATCCTTTTACATGGCCTTCCCATGGATGTGCTGTACATCTGCT
CAAAAGAAAATAATTACTTTGATGAGCGTCTTCAAAAGGACTCTTGGTGCAACAGACTCAATTGGAACTCAGCTTTTCTAACTGTCACTG
CACCAAGCTCTGCTGGAGGAGTGACCAGACTCACGATTTGGTATAGTGGGGCTCTCAAGCATCTTCAATTTGAATGTACATGCTGCTGAG
GAGCCGGTGAAGTCATCAGTTCCGCACATCCCTTCTACCCTCCAACTGCATGGGAAGCCAAAGTCCTGGTTTTGAAATGCTTGGGCAGCT
CAGCCGCTTGCCCTCACCCTGCATGTCTTGTTACTGGGTCTCCCTGTGTACTTGTGGCATTATCCACAACCATCATGTTTCTTAGGTGCC
AAACATTTACAGAAACATTTTCATATATCTTGGGGTCAGAGAAAGGGACAGATACAGAAGGACCTTGCTTGCAGGAAGCCATGCAGTTAG
TTTCTGCAGTTAGTCGTGTGAGGCTAGGTGGTTGGGCAGGCCTCGGGCTGTAGGTGTTGGGTGGGAAAAAGACCCAAGGGCCTGAAAGGG
AGGGAAAGGGGAGGGTAGCGGGAGGGTAGCAGGTGAGTTCCTAGGGCTGGAAGGTTTAGCAGCAGCCTGGTGCAGTGCCCTGTCATCAAG
ACAAACCCACGGTCCTCCTGGGTGCCTACCAAGCTTGGTTTGTACAAAAGCAAGGTGGGAGTCTATTTTTGTACATGAGATACATCACAC
TTACCTGTGGGCCAGTATTGTGAAGTGAGTCTGAGTTGTTTACACTGATGCCTTCCCTGCCCACCACAAATTGTGTACATAGTCTTCAGA
TGATACCACCCCTTTCCCCAGCTCCCAACCAAGAGCTGGTTCTAGGCCTGTGTTATATGTCATATTTAGCGTTTTTATATATGACCTTTG
ATTTCTGTTGTTTGTATTTTAGCACAGTGTATGCACCTTCATTTAAATACATCTGTGTGCATACAGATACGCATATATGTGTGTGCGTAT
GCATATATCTCTCATCTGTAGTTTCCAAGAGTTCAGCTGAAGCAGATGGAGTCCTGCAGCCCAGGAGACACCCTGCATCCCTGCTAATAG
TGTTTGCCACAAGTATTAGTGAGTCTTCCTTATTAATATTTTCATTTCAGAAGACTGAAGCAAAGCTGATAGTGTTTGCTGTTTCTTTGG
CAGCTAAGTGAGGGTCTTGGGATGACTTGCTGTGTTCCTCAAGCTGCACTTTGGGGCCATCTCTGCAGTATTAGCCCCCTTTTTGCTTGG
TGGTACTCTGTCTGTGCCTGTGTGTGTGTGTGATAGTCACTCTTGCATGGCTTCCATGTCTGGTTTGTGGCATTTGGGGATAAGGTGCTG
AAGCCAGAGCATTTGCAGTTTGTTTGAGGCCTCGTTGCCAATGATAGATCACTCCTGTTGACCTGGTATGTCTGCTTGCTTGCTGCTTTT
CCTTGCTTTCTCTTGGAAGAGGAAAGGACTCTGGTCAGGCCCAGGCTGAGTGAGATGAGCTGCAGCTGGCTCATGGCCTTCTTAGAGCAG
AGAGAGGAGTATGTCATTTTACTAAGTTCCTAAACAAACATTTATGCAGGCAACACTCCTTGCAGATCCAGAAACTGAGGCACAATAGGG
TTATGACTTGCTCAAGAATATGTAGCTGCTAGGGGGTAAATCAAGGCATCACAATTTCTGTTCAGCGGGCAGGAATAGGCTGTGAATTGC
TAGCACTTTTTTTTTTTAAGCAATTACTTTTTGACTTGTTCCTCTGAAAGTGCAAGAGGCGTACACCTTTCCCAAATGTAGACTAGAATC
TGCAGGATGCCACCCACTGTATAGTTCTGCTTTCCCAGAGAGGAAGAACTTTTAGAAACCAAATGATCTTAATTGTTATTGCCCACCCCT
GGCTTTTCCGGGTAGAAAATTCACAGTAGGAATGATTGTTAAGAGAGAGTGCTTGGAACCATGGGTTAACAGGAAAGGCTACCTAACTTC
ACATATCTGCAACCAGAGCAGCCACCAAGCATTACTTAGCAGCAGGAAAATGATTGTATTTGAGTTCCTGTGTGTCCAAAACTGAGCACC
ATGTTCTTTGAAAACATGCCACCTCAAGGCTGGGCGCGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATCA
CCGGAGGTCGGGAGTTTGAGACCAGCCTGACCAACATGGAGAAACCCCATCTCTACTAAAAATACAAAATTAGCCGGGCGTGGTGGCATG
CGCCTATAATCTCAGCTACTTGGGAGGCTGAGGCAGGAGAATTGCTTGAACCCAGGAGGCGGAGGTTGCGGTGAGTTGAGATCGTGCCAT
TGCACTCCGGCCTGGGCAACAACAGCAAAACTCCGTCTCAAAAAAAAAAAAAAAAAAATGCCACCTCACAGTCTCTATCGTTGGGCCCTG
TGGTTGCAAAGCTGCCTCCTGAATTAAGAAGGAAAGGGAAAAGATATAGCTGGAAGCGAGTGGAAGAGATGCTGAGGGCTGGGGCTGCAC
AGACGTGCTCAGCAGGGCTACAGGTGCTCAAGCCCTATTGGGGATGGGTGGGGAGTGGGGCAGCGGCGTTTGCCACCTTAAGAATTGGGG
CCAAAGCCACTGATGTTTATTTGACAGTGACACTGCACTGGGTACTTAAAGAAATTATTTCCCGTTGTAATTATAATTACTGCTTATTAA
GGAAAATATGGGAATTTTAGAAAGAATCAAGTTTGCCACCCAAATGCTACCACTGTTAATCTTTTGGTGTTAAATGTTCCCCCTAGACAT
TTCTGTGCATAGATTTTTGGTGTGTTTACATAGTCGTTATTCTGTATATACAATTTTATGTCCCTTTTGTACTTAACGTATAAACATTTT

>In-frame_PBRM1_ENST00000337303_chr3_52712516_-_WDR82_ENST00000296490_chr3_52304825_-_4089nt
TCCATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCA
GGCCCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGAC
TATAAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGACCAAAGAGAACCCTGTACAGTAAGAAATAT
GGTGTGGACCTCATCAGATACACTCATGCAGCAAACACAGTTGTTTACAGCTCTAACAAAATAGACGATACTATTCGTTACTTGTCCTTG
CATGACAACAAATACATCAGATACTTTCCTGGACATAGCAAAAGGGTGGTGGCCTTGTCCATGTCACCTGTGGATGACACTTTCATTTCT
GGGTCTCTTGATAAGACCATTCGACTCTGGGATCTCCGGTCTCCTAACTGCCAGGGCCTCATGCATCTGCAGGGGAAGCCAGTTTGTTCT
TTTGATCCAGAAGGGTTAATTTTCGCTGCAGGTGTCAACTCTGAAATGGTCAAGCTTTATGACCTTCGTTCTTTTGATAAGGGGCCATTT
GCTACCTTTAAGATGCAGTATGATCGAACTTGTGAGTGGACAGGACTTAAATTCAGCAATGATGGCAAGCTCATCCTCATTTCCACCAAC
GGCAGCTTCATTCGTCTGATTGATGCATTCAAAGGAGTGGTGATGCACACATTTGGGGGTTATGCCAACAGCAAAGCTGTCACACTGGAG
GCTTCATTTACTCCAGACTCTCAGTTTATTATGATTGGTTCAGAGGATGGCAAGATCCATGTCTGGAATGGAGAGAGCGGTATAAAAGTA
GCTGTGTTGGATGGTAAACACACAGGCCCGATTACCTGTTTGCAATTCAACCCCAAGTTCATGACTTTTGCCAGTGCGTGTTCCAACATG
GCCTTTTGGTTGCCCACCATTGATGACTGACCCTGTTGCTGCTTGGCTATTTCTGTATAGTGAGGGCGGCCAGCAGGAAGAAACTCAGAG
GGAACTGAGATAATAGTGGGATTGGATCATTTGACTGGGCTGGAGAACATCCTTTTACATGGCCTTCCCATGGATGTGCTGTACATCTGC
TCAAAAGAAAATAATTACTTTGATGAGCGTCTTCAAAAGGACTCTTGGTGCAACAGACTCAATTGGAACTCAGCTTTTCTAACTGTCACT
GCACCAAGCTCTGCTGGAGGAGTGACCAGACTCACGATTTGGTATAGTGGGGCTCTCAAGCATCTTCAATTTGAATGTACATGCTGCTGA
GGAGCCGGTGAAGTCATCAGTTCCGCACATCCCTTCTACCCTCCAACTGCATGGGAAGCCAAAGTCCTGGTTTTGAAATGCTTGGGCAGC
TCAGCCGCTTGCCCTCACCCTGCATGTCTTGTTACTGGGTCTCCCTGTGTACTTGTGGCATTATCCACAACCATCATGTTTCTTAGGTGC
CAAACATTTACAGAAACATTTTCATATATCTTGGGGTCAGAGAAAGGGACAGATACAGAAGGACCTTGCTTGCAGGAAGCCATGCAGTTA
GTTTCTGCAGTTAGTCGTGTGAGGCTAGGTGGTTGGGCAGGCCTCGGGCTGTAGGTGTTGGGTGGGAAAAAGACCCAAGGGCCTGAAAGG
GAGGGAAAGGGGAGGGTAGCGGGAGGGTAGCAGGTGAGTTCCTAGGGCTGGAAGGTTTAGCAGCAGCCTGGTGCAGTGCCCTGTCATCAA
GACAAACCCACGGTCCTCCTGGGTGCCTACCAAGCTTGGTTTGTACAAAAGCAAGGTGGGAGTCTATTTTTGTACATGAGATACATCACA
CTTACCTGTGGGCCAGTATTGTGAAGTGAGTCTGAGTTGTTTACACTGATGCCTTCCCTGCCCACCACAAATTGTGTACATAGTCTTCAG
ATGATACCACCCCTTTCCCCAGCTCCCAACCAAGAGCTGGTTCTAGGCCTGTGTTATATGTCATATTTAGCGTTTTTATATATGACCTTT
GATTTCTGTTGTTTGTATTTTAGCACAGTGTATGCACCTTCATTTAAATACATCTGTGTGCATACAGATACGCATATATGTGTGTGCGTA
TGCATATATCTCTCATCTGTAGTTTCCAAGAGTTCAGCTGAAGCAGATGGAGTCCTGCAGCCCAGGAGACACCCTGCATCCCTGCTAATA
GTGTTTGCCACAAGTATTAGTGAGTCTTCCTTATTAATATTTTCATTTCAGAAGACTGAAGCAAAGCTGATAGTGTTTGCTGTTTCTTTG
GCAGCTAAGTGAGGGTCTTGGGATGACTTGCTGTGTTCCTCAAGCTGCACTTTGGGGCCATCTCTGCAGTATTAGCCCCCTTTTTGCTTG
GTGGTACTCTGTCTGTGCCTGTGTGTGTGTGTGATAGTCACTCTTGCATGGCTTCCATGTCTGGTTTGTGGCATTTGGGGATAAGGTGCT
GAAGCCAGAGCATTTGCAGTTTGTTTGAGGCCTCGTTGCCAATGATAGATCACTCCTGTTGACCTGGTATGTCTGCTTGCTTGCTGCTTT
TCCTTGCTTTCTCTTGGAAGAGGAAAGGACTCTGGTCAGGCCCAGGCTGAGTGAGATGAGCTGCAGCTGGCTCATGGCCTTCTTAGAGCA
GAGAGAGGAGTATGTCATTTTACTAAGTTCCTAAACAAACATTTATGCAGGCAACACTCCTTGCAGATCCAGAAACTGAGGCACAATAGG
GTTATGACTTGCTCAAGAATATGTAGCTGCTAGGGGGTAAATCAAGGCATCACAATTTCTGTTCAGCGGGCAGGAATAGGCTGTGAATTG
CTAGCACTTTTTTTTTTTAAGCAATTACTTTTTGACTTGTTCCTCTGAAAGTGCAAGAGGCGTACACCTTTCCCAAATGTAGACTAGAAT
CTGCAGGATGCCACCCACTGTATAGTTCTGCTTTCCCAGAGAGGAAGAACTTTTAGAAACCAAATGATCTTAATTGTTATTGCCCACCCC
TGGCTTTTCCGGGTAGAAAATTCACAGTAGGAATGATTGTTAAGAGAGAGTGCTTGGAACCATGGGTTAACAGGAAAGGCTACCTAACTT
CACATATCTGCAACCAGAGCAGCCACCAAGCATTACTTAGCAGCAGGAAAATGATTGTATTTGAGTTCCTGTGTGTCCAAAACTGAGCAC
CATGTTCTTTGAAAACATGCCACCTCAAGGCTGGGCGCGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATC
ACCGGAGGTCGGGAGTTTGAGACCAGCCTGACCAACATGGAGAAACCCCATCTCTACTAAAAATACAAAATTAGCCGGGCGTGGTGGCAT
GCGCCTATAATCTCAGCTACTTGGGAGGCTGAGGCAGGAGAATTGCTTGAACCCAGGAGGCGGAGGTTGCGGTGAGTTGAGATCGTGCCA
TTGCACTCCGGCCTGGGCAACAACAGCAAAACTCCGTCTCAAAAAAAAAAAAAAAAAAATGCCACCTCACAGTCTCTATCGTTGGGCCCT
GTGGTTGCAAAGCTGCCTCCTGAATTAAGAAGGAAAGGGAAAAGATATAGCTGGAAGCGAGTGGAAGAGATGCTGAGGGCTGGGGCTGCA
CAGACGTGCTCAGCAGGGCTACAGGTGCTCAAGCCCTATTGGGGATGGGTGGGGAGTGGGGCAGCGGCGTTTGCCACCTTAAGAATTGGG
GCCAAAGCCACTGATGTTTATTTGACAGTGACACTGCACTGGGTACTTAAAGAAATTATTTCCCGTTGTAATTATAATTACTGCTTATTA
AGGAAAATATGGGAATTTTAGAAAGAATCAAGTTTGCCACCCAAATGCTACCACTGTTAATCTTTTGGTGTTAAATGTTCCCCCTAGACA
TTTCTGTGCATAGATTTTTGGTGTGTTTACATAGTCGTTATTCTGTATATACAATTTTATGTCCCTTTTGTACTTAACGTATAAACATTT

>In-frame_PBRM1_ENST00000410007_chr3_52712516_-_WDR82_ENST00000296490_chr3_52304825_-_4089nt
TCCATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCA
GGCCCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGAC
TATAAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGACCAAAGAGAACCCTGTACAGTAAGAAATAT
GGTGTGGACCTCATCAGATACACTCATGCAGCAAACACAGTTGTTTACAGCTCTAACAAAATAGACGATACTATTCGTTACTTGTCCTTG
CATGACAACAAATACATCAGATACTTTCCTGGACATAGCAAAAGGGTGGTGGCCTTGTCCATGTCACCTGTGGATGACACTTTCATTTCT
GGGTCTCTTGATAAGACCATTCGACTCTGGGATCTCCGGTCTCCTAACTGCCAGGGCCTCATGCATCTGCAGGGGAAGCCAGTTTGTTCT
TTTGATCCAGAAGGGTTAATTTTCGCTGCAGGTGTCAACTCTGAAATGGTCAAGCTTTATGACCTTCGTTCTTTTGATAAGGGGCCATTT
GCTACCTTTAAGATGCAGTATGATCGAACTTGTGAGTGGACAGGACTTAAATTCAGCAATGATGGCAAGCTCATCCTCATTTCCACCAAC
GGCAGCTTCATTCGTCTGATTGATGCATTCAAAGGAGTGGTGATGCACACATTTGGGGGTTATGCCAACAGCAAAGCTGTCACACTGGAG
GCTTCATTTACTCCAGACTCTCAGTTTATTATGATTGGTTCAGAGGATGGCAAGATCCATGTCTGGAATGGAGAGAGCGGTATAAAAGTA
GCTGTGTTGGATGGTAAACACACAGGCCCGATTACCTGTTTGCAATTCAACCCCAAGTTCATGACTTTTGCCAGTGCGTGTTCCAACATG
GCCTTTTGGTTGCCCACCATTGATGACTGACCCTGTTGCTGCTTGGCTATTTCTGTATAGTGAGGGCGGCCAGCAGGAAGAAACTCAGAG
GGAACTGAGATAATAGTGGGATTGGATCATTTGACTGGGCTGGAGAACATCCTTTTACATGGCCTTCCCATGGATGTGCTGTACATCTGC
TCAAAAGAAAATAATTACTTTGATGAGCGTCTTCAAAAGGACTCTTGGTGCAACAGACTCAATTGGAACTCAGCTTTTCTAACTGTCACT
GCACCAAGCTCTGCTGGAGGAGTGACCAGACTCACGATTTGGTATAGTGGGGCTCTCAAGCATCTTCAATTTGAATGTACATGCTGCTGA
GGAGCCGGTGAAGTCATCAGTTCCGCACATCCCTTCTACCCTCCAACTGCATGGGAAGCCAAAGTCCTGGTTTTGAAATGCTTGGGCAGC
TCAGCCGCTTGCCCTCACCCTGCATGTCTTGTTACTGGGTCTCCCTGTGTACTTGTGGCATTATCCACAACCATCATGTTTCTTAGGTGC
CAAACATTTACAGAAACATTTTCATATATCTTGGGGTCAGAGAAAGGGACAGATACAGAAGGACCTTGCTTGCAGGAAGCCATGCAGTTA
GTTTCTGCAGTTAGTCGTGTGAGGCTAGGTGGTTGGGCAGGCCTCGGGCTGTAGGTGTTGGGTGGGAAAAAGACCCAAGGGCCTGAAAGG
GAGGGAAAGGGGAGGGTAGCGGGAGGGTAGCAGGTGAGTTCCTAGGGCTGGAAGGTTTAGCAGCAGCCTGGTGCAGTGCCCTGTCATCAA
GACAAACCCACGGTCCTCCTGGGTGCCTACCAAGCTTGGTTTGTACAAAAGCAAGGTGGGAGTCTATTTTTGTACATGAGATACATCACA
CTTACCTGTGGGCCAGTATTGTGAAGTGAGTCTGAGTTGTTTACACTGATGCCTTCCCTGCCCACCACAAATTGTGTACATAGTCTTCAG
ATGATACCACCCCTTTCCCCAGCTCCCAACCAAGAGCTGGTTCTAGGCCTGTGTTATATGTCATATTTAGCGTTTTTATATATGACCTTT
GATTTCTGTTGTTTGTATTTTAGCACAGTGTATGCACCTTCATTTAAATACATCTGTGTGCATACAGATACGCATATATGTGTGTGCGTA
TGCATATATCTCTCATCTGTAGTTTCCAAGAGTTCAGCTGAAGCAGATGGAGTCCTGCAGCCCAGGAGACACCCTGCATCCCTGCTAATA
GTGTTTGCCACAAGTATTAGTGAGTCTTCCTTATTAATATTTTCATTTCAGAAGACTGAAGCAAAGCTGATAGTGTTTGCTGTTTCTTTG
GCAGCTAAGTGAGGGTCTTGGGATGACTTGCTGTGTTCCTCAAGCTGCACTTTGGGGCCATCTCTGCAGTATTAGCCCCCTTTTTGCTTG
GTGGTACTCTGTCTGTGCCTGTGTGTGTGTGTGATAGTCACTCTTGCATGGCTTCCATGTCTGGTTTGTGGCATTTGGGGATAAGGTGCT
GAAGCCAGAGCATTTGCAGTTTGTTTGAGGCCTCGTTGCCAATGATAGATCACTCCTGTTGACCTGGTATGTCTGCTTGCTTGCTGCTTT
TCCTTGCTTTCTCTTGGAAGAGGAAAGGACTCTGGTCAGGCCCAGGCTGAGTGAGATGAGCTGCAGCTGGCTCATGGCCTTCTTAGAGCA
GAGAGAGGAGTATGTCATTTTACTAAGTTCCTAAACAAACATTTATGCAGGCAACACTCCTTGCAGATCCAGAAACTGAGGCACAATAGG
GTTATGACTTGCTCAAGAATATGTAGCTGCTAGGGGGTAAATCAAGGCATCACAATTTCTGTTCAGCGGGCAGGAATAGGCTGTGAATTG
CTAGCACTTTTTTTTTTTAAGCAATTACTTTTTGACTTGTTCCTCTGAAAGTGCAAGAGGCGTACACCTTTCCCAAATGTAGACTAGAAT
CTGCAGGATGCCACCCACTGTATAGTTCTGCTTTCCCAGAGAGGAAGAACTTTTAGAAACCAAATGATCTTAATTGTTATTGCCCACCCC
TGGCTTTTCCGGGTAGAAAATTCACAGTAGGAATGATTGTTAAGAGAGAGTGCTTGGAACCATGGGTTAACAGGAAAGGCTACCTAACTT
CACATATCTGCAACCAGAGCAGCCACCAAGCATTACTTAGCAGCAGGAAAATGATTGTATTTGAGTTCCTGTGTGTCCAAAACTGAGCAC
CATGTTCTTTGAAAACATGCCACCTCAAGGCTGGGCGCGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATC
ACCGGAGGTCGGGAGTTTGAGACCAGCCTGACCAACATGGAGAAACCCCATCTCTACTAAAAATACAAAATTAGCCGGGCGTGGTGGCAT
GCGCCTATAATCTCAGCTACTTGGGAGGCTGAGGCAGGAGAATTGCTTGAACCCAGGAGGCGGAGGTTGCGGTGAGTTGAGATCGTGCCA
TTGCACTCCGGCCTGGGCAACAACAGCAAAACTCCGTCTCAAAAAAAAAAAAAAAAAAATGCCACCTCACAGTCTCTATCGTTGGGCCCT
GTGGTTGCAAAGCTGCCTCCTGAATTAAGAAGGAAAGGGAAAAGATATAGCTGGAAGCGAGTGGAAGAGATGCTGAGGGCTGGGGCTGCA
CAGACGTGCTCAGCAGGGCTACAGGTGCTCAAGCCCTATTGGGGATGGGTGGGGAGTGGGGCAGCGGCGTTTGCCACCTTAAGAATTGGG
GCCAAAGCCACTGATGTTTATTTGACAGTGACACTGCACTGGGTACTTAAAGAAATTATTTCCCGTTGTAATTATAATTACTGCTTATTA
AGGAAAATATGGGAATTTTAGAAAGAATCAAGTTTGCCACCCAAATGCTACCACTGTTAATCTTTTGGTGTTAAATGTTCCCCCTAGACA
TTTCTGTGCATAGATTTTTGGTGTGTTTACATAGTCGTTATTCTGTATATACAATTTTATGTCCCTTTTGTACTTAACGTATAAACATTT

>In-frame_PBRM1_ENST00000409057_chr3_52712516_-_WDR82_ENST00000296490_chr3_52304825_-_4089nt
TCCATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCA
GGCCCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGAC
TATAAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGACCAAAGAGAACCCTGTACAGTAAGAAATAT
GGTGTGGACCTCATCAGATACACTCATGCAGCAAACACAGTTGTTTACAGCTCTAACAAAATAGACGATACTATTCGTTACTTGTCCTTG
CATGACAACAAATACATCAGATACTTTCCTGGACATAGCAAAAGGGTGGTGGCCTTGTCCATGTCACCTGTGGATGACACTTTCATTTCT
GGGTCTCTTGATAAGACCATTCGACTCTGGGATCTCCGGTCTCCTAACTGCCAGGGCCTCATGCATCTGCAGGGGAAGCCAGTTTGTTCT
TTTGATCCAGAAGGGTTAATTTTCGCTGCAGGTGTCAACTCTGAAATGGTCAAGCTTTATGACCTTCGTTCTTTTGATAAGGGGCCATTT
GCTACCTTTAAGATGCAGTATGATCGAACTTGTGAGTGGACAGGACTTAAATTCAGCAATGATGGCAAGCTCATCCTCATTTCCACCAAC
GGCAGCTTCATTCGTCTGATTGATGCATTCAAAGGAGTGGTGATGCACACATTTGGGGGTTATGCCAACAGCAAAGCTGTCACACTGGAG
GCTTCATTTACTCCAGACTCTCAGTTTATTATGATTGGTTCAGAGGATGGCAAGATCCATGTCTGGAATGGAGAGAGCGGTATAAAAGTA
GCTGTGTTGGATGGTAAACACACAGGCCCGATTACCTGTTTGCAATTCAACCCCAAGTTCATGACTTTTGCCAGTGCGTGTTCCAACATG
GCCTTTTGGTTGCCCACCATTGATGACTGACCCTGTTGCTGCTTGGCTATTTCTGTATAGTGAGGGCGGCCAGCAGGAAGAAACTCAGAG
GGAACTGAGATAATAGTGGGATTGGATCATTTGACTGGGCTGGAGAACATCCTTTTACATGGCCTTCCCATGGATGTGCTGTACATCTGC
TCAAAAGAAAATAATTACTTTGATGAGCGTCTTCAAAAGGACTCTTGGTGCAACAGACTCAATTGGAACTCAGCTTTTCTAACTGTCACT
GCACCAAGCTCTGCTGGAGGAGTGACCAGACTCACGATTTGGTATAGTGGGGCTCTCAAGCATCTTCAATTTGAATGTACATGCTGCTGA
GGAGCCGGTGAAGTCATCAGTTCCGCACATCCCTTCTACCCTCCAACTGCATGGGAAGCCAAAGTCCTGGTTTTGAAATGCTTGGGCAGC
TCAGCCGCTTGCCCTCACCCTGCATGTCTTGTTACTGGGTCTCCCTGTGTACTTGTGGCATTATCCACAACCATCATGTTTCTTAGGTGC
CAAACATTTACAGAAACATTTTCATATATCTTGGGGTCAGAGAAAGGGACAGATACAGAAGGACCTTGCTTGCAGGAAGCCATGCAGTTA
GTTTCTGCAGTTAGTCGTGTGAGGCTAGGTGGTTGGGCAGGCCTCGGGCTGTAGGTGTTGGGTGGGAAAAAGACCCAAGGGCCTGAAAGG
GAGGGAAAGGGGAGGGTAGCGGGAGGGTAGCAGGTGAGTTCCTAGGGCTGGAAGGTTTAGCAGCAGCCTGGTGCAGTGCCCTGTCATCAA
GACAAACCCACGGTCCTCCTGGGTGCCTACCAAGCTTGGTTTGTACAAAAGCAAGGTGGGAGTCTATTTTTGTACATGAGATACATCACA
CTTACCTGTGGGCCAGTATTGTGAAGTGAGTCTGAGTTGTTTACACTGATGCCTTCCCTGCCCACCACAAATTGTGTACATAGTCTTCAG
ATGATACCACCCCTTTCCCCAGCTCCCAACCAAGAGCTGGTTCTAGGCCTGTGTTATATGTCATATTTAGCGTTTTTATATATGACCTTT
GATTTCTGTTGTTTGTATTTTAGCACAGTGTATGCACCTTCATTTAAATACATCTGTGTGCATACAGATACGCATATATGTGTGTGCGTA
TGCATATATCTCTCATCTGTAGTTTCCAAGAGTTCAGCTGAAGCAGATGGAGTCCTGCAGCCCAGGAGACACCCTGCATCCCTGCTAATA
GTGTTTGCCACAAGTATTAGTGAGTCTTCCTTATTAATATTTTCATTTCAGAAGACTGAAGCAAAGCTGATAGTGTTTGCTGTTTCTTTG
GCAGCTAAGTGAGGGTCTTGGGATGACTTGCTGTGTTCCTCAAGCTGCACTTTGGGGCCATCTCTGCAGTATTAGCCCCCTTTTTGCTTG
GTGGTACTCTGTCTGTGCCTGTGTGTGTGTGTGATAGTCACTCTTGCATGGCTTCCATGTCTGGTTTGTGGCATTTGGGGATAAGGTGCT
GAAGCCAGAGCATTTGCAGTTTGTTTGAGGCCTCGTTGCCAATGATAGATCACTCCTGTTGACCTGGTATGTCTGCTTGCTTGCTGCTTT
TCCTTGCTTTCTCTTGGAAGAGGAAAGGACTCTGGTCAGGCCCAGGCTGAGTGAGATGAGCTGCAGCTGGCTCATGGCCTTCTTAGAGCA
GAGAGAGGAGTATGTCATTTTACTAAGTTCCTAAACAAACATTTATGCAGGCAACACTCCTTGCAGATCCAGAAACTGAGGCACAATAGG
GTTATGACTTGCTCAAGAATATGTAGCTGCTAGGGGGTAAATCAAGGCATCACAATTTCTGTTCAGCGGGCAGGAATAGGCTGTGAATTG
CTAGCACTTTTTTTTTTTAAGCAATTACTTTTTGACTTGTTCCTCTGAAAGTGCAAGAGGCGTACACCTTTCCCAAATGTAGACTAGAAT
CTGCAGGATGCCACCCACTGTATAGTTCTGCTTTCCCAGAGAGGAAGAACTTTTAGAAACCAAATGATCTTAATTGTTATTGCCCACCCC
TGGCTTTTCCGGGTAGAAAATTCACAGTAGGAATGATTGTTAAGAGAGAGTGCTTGGAACCATGGGTTAACAGGAAAGGCTACCTAACTT
CACATATCTGCAACCAGAGCAGCCACCAAGCATTACTTAGCAGCAGGAAAATGATTGTATTTGAGTTCCTGTGTGTCCAAAACTGAGCAC
CATGTTCTTTGAAAACATGCCACCTCAAGGCTGGGCGCGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATC
ACCGGAGGTCGGGAGTTTGAGACCAGCCTGACCAACATGGAGAAACCCCATCTCTACTAAAAATACAAAATTAGCCGGGCGTGGTGGCAT
GCGCCTATAATCTCAGCTACTTGGGAGGCTGAGGCAGGAGAATTGCTTGAACCCAGGAGGCGGAGGTTGCGGTGAGTTGAGATCGTGCCA
TTGCACTCCGGCCTGGGCAACAACAGCAAAACTCCGTCTCAAAAAAAAAAAAAAAAAAATGCCACCTCACAGTCTCTATCGTTGGGCCCT
GTGGTTGCAAAGCTGCCTCCTGAATTAAGAAGGAAAGGGAAAAGATATAGCTGGAAGCGAGTGGAAGAGATGCTGAGGGCTGGGGCTGCA
CAGACGTGCTCAGCAGGGCTACAGGTGCTCAAGCCCTATTGGGGATGGGTGGGGAGTGGGGCAGCGGCGTTTGCCACCTTAAGAATTGGG
GCCAAAGCCACTGATGTTTATTTGACAGTGACACTGCACTGGGTACTTAAAGAAATTATTTCCCGTTGTAATTATAATTACTGCTTATTA
AGGAAAATATGGGAATTTTAGAAAGAATCAAGTTTGCCACCCAAATGCTACCACTGTTAATCTTTTGGTGTTAAATGTTCCCCCTAGACA
TTTCTGTGCATAGATTTTTGGTGTGTTTACATAGTCGTTATTCTGTATATACAATTTTATGTCCCTTTTGTACTTAACGTATAAACATTT

>In-frame_PBRM1_ENST00000409114_chr3_52712516_-_WDR82_ENST00000296490_chr3_52304825_-_4089nt
TCCATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCA
GGCCCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGAC
TATAAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGACCAAAGAGAACCCTGTACAGTAAGAAATAT
GGTGTGGACCTCATCAGATACACTCATGCAGCAAACACAGTTGTTTACAGCTCTAACAAAATAGACGATACTATTCGTTACTTGTCCTTG
CATGACAACAAATACATCAGATACTTTCCTGGACATAGCAAAAGGGTGGTGGCCTTGTCCATGTCACCTGTGGATGACACTTTCATTTCT
GGGTCTCTTGATAAGACCATTCGACTCTGGGATCTCCGGTCTCCTAACTGCCAGGGCCTCATGCATCTGCAGGGGAAGCCAGTTTGTTCT
TTTGATCCAGAAGGGTTAATTTTCGCTGCAGGTGTCAACTCTGAAATGGTCAAGCTTTATGACCTTCGTTCTTTTGATAAGGGGCCATTT
GCTACCTTTAAGATGCAGTATGATCGAACTTGTGAGTGGACAGGACTTAAATTCAGCAATGATGGCAAGCTCATCCTCATTTCCACCAAC
GGCAGCTTCATTCGTCTGATTGATGCATTCAAAGGAGTGGTGATGCACACATTTGGGGGTTATGCCAACAGCAAAGCTGTCACACTGGAG
GCTTCATTTACTCCAGACTCTCAGTTTATTATGATTGGTTCAGAGGATGGCAAGATCCATGTCTGGAATGGAGAGAGCGGTATAAAAGTA
GCTGTGTTGGATGGTAAACACACAGGCCCGATTACCTGTTTGCAATTCAACCCCAAGTTCATGACTTTTGCCAGTGCGTGTTCCAACATG
GCCTTTTGGTTGCCCACCATTGATGACTGACCCTGTTGCTGCTTGGCTATTTCTGTATAGTGAGGGCGGCCAGCAGGAAGAAACTCAGAG
GGAACTGAGATAATAGTGGGATTGGATCATTTGACTGGGCTGGAGAACATCCTTTTACATGGCCTTCCCATGGATGTGCTGTACATCTGC
TCAAAAGAAAATAATTACTTTGATGAGCGTCTTCAAAAGGACTCTTGGTGCAACAGACTCAATTGGAACTCAGCTTTTCTAACTGTCACT
GCACCAAGCTCTGCTGGAGGAGTGACCAGACTCACGATTTGGTATAGTGGGGCTCTCAAGCATCTTCAATTTGAATGTACATGCTGCTGA
GGAGCCGGTGAAGTCATCAGTTCCGCACATCCCTTCTACCCTCCAACTGCATGGGAAGCCAAAGTCCTGGTTTTGAAATGCTTGGGCAGC
TCAGCCGCTTGCCCTCACCCTGCATGTCTTGTTACTGGGTCTCCCTGTGTACTTGTGGCATTATCCACAACCATCATGTTTCTTAGGTGC
CAAACATTTACAGAAACATTTTCATATATCTTGGGGTCAGAGAAAGGGACAGATACAGAAGGACCTTGCTTGCAGGAAGCCATGCAGTTA
GTTTCTGCAGTTAGTCGTGTGAGGCTAGGTGGTTGGGCAGGCCTCGGGCTGTAGGTGTTGGGTGGGAAAAAGACCCAAGGGCCTGAAAGG
GAGGGAAAGGGGAGGGTAGCGGGAGGGTAGCAGGTGAGTTCCTAGGGCTGGAAGGTTTAGCAGCAGCCTGGTGCAGTGCCCTGTCATCAA
GACAAACCCACGGTCCTCCTGGGTGCCTACCAAGCTTGGTTTGTACAAAAGCAAGGTGGGAGTCTATTTTTGTACATGAGATACATCACA
CTTACCTGTGGGCCAGTATTGTGAAGTGAGTCTGAGTTGTTTACACTGATGCCTTCCCTGCCCACCACAAATTGTGTACATAGTCTTCAG
ATGATACCACCCCTTTCCCCAGCTCCCAACCAAGAGCTGGTTCTAGGCCTGTGTTATATGTCATATTTAGCGTTTTTATATATGACCTTT
GATTTCTGTTGTTTGTATTTTAGCACAGTGTATGCACCTTCATTTAAATACATCTGTGTGCATACAGATACGCATATATGTGTGTGCGTA
TGCATATATCTCTCATCTGTAGTTTCCAAGAGTTCAGCTGAAGCAGATGGAGTCCTGCAGCCCAGGAGACACCCTGCATCCCTGCTAATA
GTGTTTGCCACAAGTATTAGTGAGTCTTCCTTATTAATATTTTCATTTCAGAAGACTGAAGCAAAGCTGATAGTGTTTGCTGTTTCTTTG
GCAGCTAAGTGAGGGTCTTGGGATGACTTGCTGTGTTCCTCAAGCTGCACTTTGGGGCCATCTCTGCAGTATTAGCCCCCTTTTTGCTTG
GTGGTACTCTGTCTGTGCCTGTGTGTGTGTGTGATAGTCACTCTTGCATGGCTTCCATGTCTGGTTTGTGGCATTTGGGGATAAGGTGCT
GAAGCCAGAGCATTTGCAGTTTGTTTGAGGCCTCGTTGCCAATGATAGATCACTCCTGTTGACCTGGTATGTCTGCTTGCTTGCTGCTTT
TCCTTGCTTTCTCTTGGAAGAGGAAAGGACTCTGGTCAGGCCCAGGCTGAGTGAGATGAGCTGCAGCTGGCTCATGGCCTTCTTAGAGCA
GAGAGAGGAGTATGTCATTTTACTAAGTTCCTAAACAAACATTTATGCAGGCAACACTCCTTGCAGATCCAGAAACTGAGGCACAATAGG
GTTATGACTTGCTCAAGAATATGTAGCTGCTAGGGGGTAAATCAAGGCATCACAATTTCTGTTCAGCGGGCAGGAATAGGCTGTGAATTG
CTAGCACTTTTTTTTTTTAAGCAATTACTTTTTGACTTGTTCCTCTGAAAGTGCAAGAGGCGTACACCTTTCCCAAATGTAGACTAGAAT
CTGCAGGATGCCACCCACTGTATAGTTCTGCTTTCCCAGAGAGGAAGAACTTTTAGAAACCAAATGATCTTAATTGTTATTGCCCACCCC
TGGCTTTTCCGGGTAGAAAATTCACAGTAGGAATGATTGTTAAGAGAGAGTGCTTGGAACCATGGGTTAACAGGAAAGGCTACCTAACTT
CACATATCTGCAACCAGAGCAGCCACCAAGCATTACTTAGCAGCAGGAAAATGATTGTATTTGAGTTCCTGTGTGTCCAAAACTGAGCAC
CATGTTCTTTGAAAACATGCCACCTCAAGGCTGGGCGCGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATC
ACCGGAGGTCGGGAGTTTGAGACCAGCCTGACCAACATGGAGAAACCCCATCTCTACTAAAAATACAAAATTAGCCGGGCGTGGTGGCAT
GCGCCTATAATCTCAGCTACTTGGGAGGCTGAGGCAGGAGAATTGCTTGAACCCAGGAGGCGGAGGTTGCGGTGAGTTGAGATCGTGCCA
TTGCACTCCGGCCTGGGCAACAACAGCAAAACTCCGTCTCAAAAAAAAAAAAAAAAAAATGCCACCTCACAGTCTCTATCGTTGGGCCCT
GTGGTTGCAAAGCTGCCTCCTGAATTAAGAAGGAAAGGGAAAAGATATAGCTGGAAGCGAGTGGAAGAGATGCTGAGGGCTGGGGCTGCA
CAGACGTGCTCAGCAGGGCTACAGGTGCTCAAGCCCTATTGGGGATGGGTGGGGAGTGGGGCAGCGGCGTTTGCCACCTTAAGAATTGGG
GCCAAAGCCACTGATGTTTATTTGACAGTGACACTGCACTGGGTACTTAAAGAAATTATTTCCCGTTGTAATTATAATTACTGCTTATTA
AGGAAAATATGGGAATTTTAGAAAGAATCAAGTTTGCCACCCAAATGCTACCACTGTTAATCTTTTGGTGTTAAATGTTCCCCCTAGACA
TTTCTGTGCATAGATTTTTGGTGTGTTTACATAGTCGTTATTCTGTATATACAATTTTATGTCCCTTTTGTACTTAACGTATAAACATTT

>In-frame_PBRM1_ENST00000409767_chr3_52712516_-_WDR82_ENST00000296490_chr3_52304825_-_4089nt
TCCATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCA
GGCCCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGAC
TATAAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGACCAAAGAGAACCCTGTACAGTAAGAAATAT
GGTGTGGACCTCATCAGATACACTCATGCAGCAAACACAGTTGTTTACAGCTCTAACAAAATAGACGATACTATTCGTTACTTGTCCTTG
CATGACAACAAATACATCAGATACTTTCCTGGACATAGCAAAAGGGTGGTGGCCTTGTCCATGTCACCTGTGGATGACACTTTCATTTCT
GGGTCTCTTGATAAGACCATTCGACTCTGGGATCTCCGGTCTCCTAACTGCCAGGGCCTCATGCATCTGCAGGGGAAGCCAGTTTGTTCT
TTTGATCCAGAAGGGTTAATTTTCGCTGCAGGTGTCAACTCTGAAATGGTCAAGCTTTATGACCTTCGTTCTTTTGATAAGGGGCCATTT
GCTACCTTTAAGATGCAGTATGATCGAACTTGTGAGTGGACAGGACTTAAATTCAGCAATGATGGCAAGCTCATCCTCATTTCCACCAAC
GGCAGCTTCATTCGTCTGATTGATGCATTCAAAGGAGTGGTGATGCACACATTTGGGGGTTATGCCAACAGCAAAGCTGTCACACTGGAG
GCTTCATTTACTCCAGACTCTCAGTTTATTATGATTGGTTCAGAGGATGGCAAGATCCATGTCTGGAATGGAGAGAGCGGTATAAAAGTA
GCTGTGTTGGATGGTAAACACACAGGCCCGATTACCTGTTTGCAATTCAACCCCAAGTTCATGACTTTTGCCAGTGCGTGTTCCAACATG
GCCTTTTGGTTGCCCACCATTGATGACTGACCCTGTTGCTGCTTGGCTATTTCTGTATAGTGAGGGCGGCCAGCAGGAAGAAACTCAGAG
GGAACTGAGATAATAGTGGGATTGGATCATTTGACTGGGCTGGAGAACATCCTTTTACATGGCCTTCCCATGGATGTGCTGTACATCTGC
TCAAAAGAAAATAATTACTTTGATGAGCGTCTTCAAAAGGACTCTTGGTGCAACAGACTCAATTGGAACTCAGCTTTTCTAACTGTCACT
GCACCAAGCTCTGCTGGAGGAGTGACCAGACTCACGATTTGGTATAGTGGGGCTCTCAAGCATCTTCAATTTGAATGTACATGCTGCTGA
GGAGCCGGTGAAGTCATCAGTTCCGCACATCCCTTCTACCCTCCAACTGCATGGGAAGCCAAAGTCCTGGTTTTGAAATGCTTGGGCAGC
TCAGCCGCTTGCCCTCACCCTGCATGTCTTGTTACTGGGTCTCCCTGTGTACTTGTGGCATTATCCACAACCATCATGTTTCTTAGGTGC
CAAACATTTACAGAAACATTTTCATATATCTTGGGGTCAGAGAAAGGGACAGATACAGAAGGACCTTGCTTGCAGGAAGCCATGCAGTTA
GTTTCTGCAGTTAGTCGTGTGAGGCTAGGTGGTTGGGCAGGCCTCGGGCTGTAGGTGTTGGGTGGGAAAAAGACCCAAGGGCCTGAAAGG
GAGGGAAAGGGGAGGGTAGCGGGAGGGTAGCAGGTGAGTTCCTAGGGCTGGAAGGTTTAGCAGCAGCCTGGTGCAGTGCCCTGTCATCAA
GACAAACCCACGGTCCTCCTGGGTGCCTACCAAGCTTGGTTTGTACAAAAGCAAGGTGGGAGTCTATTTTTGTACATGAGATACATCACA
CTTACCTGTGGGCCAGTATTGTGAAGTGAGTCTGAGTTGTTTACACTGATGCCTTCCCTGCCCACCACAAATTGTGTACATAGTCTTCAG
ATGATACCACCCCTTTCCCCAGCTCCCAACCAAGAGCTGGTTCTAGGCCTGTGTTATATGTCATATTTAGCGTTTTTATATATGACCTTT
GATTTCTGTTGTTTGTATTTTAGCACAGTGTATGCACCTTCATTTAAATACATCTGTGTGCATACAGATACGCATATATGTGTGTGCGTA
TGCATATATCTCTCATCTGTAGTTTCCAAGAGTTCAGCTGAAGCAGATGGAGTCCTGCAGCCCAGGAGACACCCTGCATCCCTGCTAATA
GTGTTTGCCACAAGTATTAGTGAGTCTTCCTTATTAATATTTTCATTTCAGAAGACTGAAGCAAAGCTGATAGTGTTTGCTGTTTCTTTG
GCAGCTAAGTGAGGGTCTTGGGATGACTTGCTGTGTTCCTCAAGCTGCACTTTGGGGCCATCTCTGCAGTATTAGCCCCCTTTTTGCTTG
GTGGTACTCTGTCTGTGCCTGTGTGTGTGTGTGATAGTCACTCTTGCATGGCTTCCATGTCTGGTTTGTGGCATTTGGGGATAAGGTGCT
GAAGCCAGAGCATTTGCAGTTTGTTTGAGGCCTCGTTGCCAATGATAGATCACTCCTGTTGACCTGGTATGTCTGCTTGCTTGCTGCTTT
TCCTTGCTTTCTCTTGGAAGAGGAAAGGACTCTGGTCAGGCCCAGGCTGAGTGAGATGAGCTGCAGCTGGCTCATGGCCTTCTTAGAGCA
GAGAGAGGAGTATGTCATTTTACTAAGTTCCTAAACAAACATTTATGCAGGCAACACTCCTTGCAGATCCAGAAACTGAGGCACAATAGG
GTTATGACTTGCTCAAGAATATGTAGCTGCTAGGGGGTAAATCAAGGCATCACAATTTCTGTTCAGCGGGCAGGAATAGGCTGTGAATTG
CTAGCACTTTTTTTTTTTAAGCAATTACTTTTTGACTTGTTCCTCTGAAAGTGCAAGAGGCGTACACCTTTCCCAAATGTAGACTAGAAT
CTGCAGGATGCCACCCACTGTATAGTTCTGCTTTCCCAGAGAGGAAGAACTTTTAGAAACCAAATGATCTTAATTGTTATTGCCCACCCC
TGGCTTTTCCGGGTAGAAAATTCACAGTAGGAATGATTGTTAAGAGAGAGTGCTTGGAACCATGGGTTAACAGGAAAGGCTACCTAACTT
CACATATCTGCAACCAGAGCAGCCACCAAGCATTACTTAGCAGCAGGAAAATGATTGTATTTGAGTTCCTGTGTGTCCAAAACTGAGCAC
CATGTTCTTTGAAAACATGCCACCTCAAGGCTGGGCGCGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATC
ACCGGAGGTCGGGAGTTTGAGACCAGCCTGACCAACATGGAGAAACCCCATCTCTACTAAAAATACAAAATTAGCCGGGCGTGGTGGCAT
GCGCCTATAATCTCAGCTACTTGGGAGGCTGAGGCAGGAGAATTGCTTGAACCCAGGAGGCGGAGGTTGCGGTGAGTTGAGATCGTGCCA
TTGCACTCCGGCCTGGGCAACAACAGCAAAACTCCGTCTCAAAAAAAAAAAAAAAAAAATGCCACCTCACAGTCTCTATCGTTGGGCCCT
GTGGTTGCAAAGCTGCCTCCTGAATTAAGAAGGAAAGGGAAAAGATATAGCTGGAAGCGAGTGGAAGAGATGCTGAGGGCTGGGGCTGCA
CAGACGTGCTCAGCAGGGCTACAGGTGCTCAAGCCCTATTGGGGATGGGTGGGGAGTGGGGCAGCGGCGTTTGCCACCTTAAGAATTGGG
GCCAAAGCCACTGATGTTTATTTGACAGTGACACTGCACTGGGTACTTAAAGAAATTATTTCCCGTTGTAATTATAATTACTGCTTATTA
AGGAAAATATGGGAATTTTAGAAAGAATCAAGTTTGCCACCCAAATGCTACCACTGTTAATCTTTTGGTGTTAAATGTTCCCCCTAGACA
TTTCTGTGCATAGATTTTTGGTGTGTTTACATAGTCGTTATTCTGTATATACAATTTTATGTCCCTTTTGTACTTAACGTATAAACATTT


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FusionGenePPI for PBRM1_WDR82


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
PBRM1ARID1A, SMARCC2, SMARCC1, SMARCE1, HIST1H3A, HIST1H4A, HIST2H2BE, HIST2H2AC, CHD7, ARID2, SMARCD1, ACTL6A, SMARCB1, SMARCA4, SMARCAD1, HIST3H3, SIRT7, CALML5, APP, GTF3C5, TCHHL1, NOTCH1, MAML1, ZNF512B, HECW2, CDC20, ZDHHC17, OBSL1, EED, DPF3, NUP50, COPS3, BRD7, SCARNA22, IFI16, HIST1H3E, DPPA4, NANOG, POU5F1, TOP1, HDAC6, VHL, BCL7C, BCL7A, ZBTB48, UHRF2, BRD1WDR82CXXC1, SETD1A, SETD1B, CUL4B, CUL4A, KMT2C, KMT2B, POLR2A, PYDC1, KDM6A, POLR2B, HCFC1, PAXIP1, PPP1R10, TOX4, RBM10, ASH2L, RBBP5, HSPA8, HSPA4, TCP1, CCT3, CCT7, CCT5, WDR5, PPP1CA, PPP1CB, PPP1CC, C17orf49, KMT2D, OSGEP, NAGK, HNRNPA1, GRK5, UCHL1, ULK3, VCP, BIRC2, BIRC3, RPA1, RPA2, RPA3, HUWE1, DPY30, EP300, TP53, PPP1R3A, GLOD4, GMPPB, GOT1, PPIL3, RAE1, NTRK1, XPO1, USP37


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for PBRM1_WDR82


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for PBRM1_WDR82


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgenePBRM1C0005586Bipolar Disorder3PSYGENET
HgenePBRM1C0007134Renal Cell Carcinoma2CTD_human
HgenePBRM1C0033975Psychotic Disorders1PSYGENET
HgenePBRM1C0036341Schizophrenia1PSYGENET
HgenePBRM1C0040100Thymoma1CTD_human
HgenePBRM1C0206698Cholangiocarcinoma1CTD_human
HgenePBRM1C0349204Nonorganic psychosis1PSYGENET