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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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Fusion gene ID: 26105

FusionGeneSummary for PBRM1_FBXW12

check button Fusion gene summary
Fusion gene informationFusion gene name: PBRM1_FBXW12
Fusion gene ID: 26105
HgeneTgene
Gene symbol

PBRM1

FBXW12

Gene ID

55193

285231

Gene namepolybromo 1F-box and WD repeat domain containing 12
SynonymsBAF180|PB1FBW12|FBXO12|FBXO35
Cytomap

3p21.1

3p21.31

Type of geneprotein-codingprotein-coding
Descriptionprotein polybromo-1BRG1-associated factor 180polybromo-1DF-box/WD repeat-containing protein 12F-box and WD-40 domain protein 12F-box and WD-40 domain-containing protein 12F-box only protein 35F-box- and WD40-repeat-containing protein
Modification date2018052320180519
UniProtAcc

Q86U86

Q6X9E4

Ensembl transtripts involved in fusion geneENST00000356770, ENST00000394830, 
ENST00000296302, ENST00000337303, 
ENST00000410007, ENST00000409057, 
ENST00000409114, ENST00000409767, 
ENST00000296438, ENST00000415155, 
ENST00000445170, ENST00000436231, 
ENST00000468158, 
Fusion gene scores* DoF score9 X 6 X 9=4862 X 2 X 2=8
# samples 102
** MAII scorelog2(10/486*10)=-2.28095631383106
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(2/8*10)=1.32192809488736
Context

PubMed: PBRM1 [Title/Abstract] AND FBXW12 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationTumor suppressor gene involved fusion gene, in-frame but not retained their domain.
Transcription factor involved fusion gene, inframe and retained DNA-binding domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVMESOTCGA-MQ-A4LM-01APBRM1chr3

52595783

-FBXW12chr3

48416844

+
TCGALDMESOTCGA-MQ-A4LM-01APBRM1chr3

52592265

-FBXW12chr3

48416844

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000356770ENST00000296438PBRM1chr3

52595783

-FBXW12chr3

48416844

+
In-frameENST00000356770ENST00000415155PBRM1chr3

52595783

-FBXW12chr3

48416844

+
In-frameENST00000356770ENST00000445170PBRM1chr3

52595783

-FBXW12chr3

48416844

+
5CDS-5UTRENST00000356770ENST00000436231PBRM1chr3

52595783

-FBXW12chr3

48416844

+
5CDS-intronENST00000356770ENST00000468158PBRM1chr3

52595783

-FBXW12chr3

48416844

+
Frame-shiftENST00000394830ENST00000296438PBRM1chr3

52595783

-FBXW12chr3

48416844

+
Frame-shiftENST00000394830ENST00000415155PBRM1chr3

52595783

-FBXW12chr3

48416844

+
Frame-shiftENST00000394830ENST00000445170PBRM1chr3

52595783

-FBXW12chr3

48416844

+
5CDS-5UTRENST00000394830ENST00000436231PBRM1chr3

52595783

-FBXW12chr3

48416844

+
5CDS-intronENST00000394830ENST00000468158PBRM1chr3

52595783

-FBXW12chr3

48416844

+
In-frameENST00000296302ENST00000296438PBRM1chr3

52595783

-FBXW12chr3

48416844

+
In-frameENST00000296302ENST00000415155PBRM1chr3

52595783

-FBXW12chr3

48416844

+
In-frameENST00000296302ENST00000445170PBRM1chr3

52595783

-FBXW12chr3

48416844

+
5CDS-5UTRENST00000296302ENST00000436231PBRM1chr3

52595783

-FBXW12chr3

48416844

+
5CDS-intronENST00000296302ENST00000468158PBRM1chr3

52595783

-FBXW12chr3

48416844

+
In-frameENST00000337303ENST00000296438PBRM1chr3

52595783

-FBXW12chr3

48416844

+
In-frameENST00000337303ENST00000415155PBRM1chr3

52595783

-FBXW12chr3

48416844

+
In-frameENST00000337303ENST00000445170PBRM1chr3

52595783

-FBXW12chr3

48416844

+
5CDS-5UTRENST00000337303ENST00000436231PBRM1chr3

52595783

-FBXW12chr3

48416844

+
5CDS-intronENST00000337303ENST00000468158PBRM1chr3

52595783

-FBXW12chr3

48416844

+
In-frameENST00000410007ENST00000296438PBRM1chr3

52595783

-FBXW12chr3

48416844

+
In-frameENST00000410007ENST00000415155PBRM1chr3

52595783

-FBXW12chr3

48416844

+
In-frameENST00000410007ENST00000445170PBRM1chr3

52595783

-FBXW12chr3

48416844

+
5CDS-5UTRENST00000410007ENST00000436231PBRM1chr3

52595783

-FBXW12chr3

48416844

+
5CDS-intronENST00000410007ENST00000468158PBRM1chr3

52595783

-FBXW12chr3

48416844

+
In-frameENST00000409057ENST00000296438PBRM1chr3

52595783

-FBXW12chr3

48416844

+
In-frameENST00000409057ENST00000415155PBRM1chr3

52595783

-FBXW12chr3

48416844

+
In-frameENST00000409057ENST00000445170PBRM1chr3

52595783

-FBXW12chr3

48416844

+
5CDS-5UTRENST00000409057ENST00000436231PBRM1chr3

52595783

-FBXW12chr3

48416844

+
5CDS-intronENST00000409057ENST00000468158PBRM1chr3

52595783

-FBXW12chr3

48416844

+
In-frameENST00000409114ENST00000296438PBRM1chr3

52595783

-FBXW12chr3

48416844

+
In-frameENST00000409114ENST00000415155PBRM1chr3

52595783

-FBXW12chr3

48416844

+
In-frameENST00000409114ENST00000445170PBRM1chr3

52595783

-FBXW12chr3

48416844

+
5CDS-5UTRENST00000409114ENST00000436231PBRM1chr3

52595783

-FBXW12chr3

48416844

+
5CDS-intronENST00000409114ENST00000468158PBRM1chr3

52595783

-FBXW12chr3

48416844

+
In-frameENST00000409767ENST00000296438PBRM1chr3

52595783

-FBXW12chr3

48416844

+
In-frameENST00000409767ENST00000415155PBRM1chr3

52595783

-FBXW12chr3

48416844

+
In-frameENST00000409767ENST00000445170PBRM1chr3

52595783

-FBXW12chr3

48416844

+
5CDS-5UTRENST00000409767ENST00000436231PBRM1chr3

52595783

-FBXW12chr3

48416844

+
5CDS-intronENST00000409767ENST00000468158PBRM1chr3

52595783

-FBXW12chr3

48416844

+
intron-3CDSENST00000356770ENST00000296438PBRM1chr3

52592265

-FBXW12chr3

48416844

+
intron-3CDSENST00000356770ENST00000415155PBRM1chr3

52592265

-FBXW12chr3

48416844

+
intron-3CDSENST00000356770ENST00000445170PBRM1chr3

52592265

-FBXW12chr3

48416844

+
intron-5UTRENST00000356770ENST00000436231PBRM1chr3

52592265

-FBXW12chr3

48416844

+
intron-intronENST00000356770ENST00000468158PBRM1chr3

52592265

-FBXW12chr3

48416844

+
intron-3CDSENST00000394830ENST00000296438PBRM1chr3

52592265

-FBXW12chr3

48416844

+
intron-3CDSENST00000394830ENST00000415155PBRM1chr3

52592265

-FBXW12chr3

48416844

+
intron-3CDSENST00000394830ENST00000445170PBRM1chr3

52592265

-FBXW12chr3

48416844

+
intron-5UTRENST00000394830ENST00000436231PBRM1chr3

52592265

-FBXW12chr3

48416844

+
intron-intronENST00000394830ENST00000468158PBRM1chr3

52592265

-FBXW12chr3

48416844

+
In-frameENST00000296302ENST00000296438PBRM1chr3

52592265

-FBXW12chr3

48416844

+
In-frameENST00000296302ENST00000415155PBRM1chr3

52592265

-FBXW12chr3

48416844

+
In-frameENST00000296302ENST00000445170PBRM1chr3

52592265

-FBXW12chr3

48416844

+
5CDS-5UTRENST00000296302ENST00000436231PBRM1chr3

52592265

-FBXW12chr3

48416844

+
5CDS-intronENST00000296302ENST00000468158PBRM1chr3

52592265

-FBXW12chr3

48416844

+
intron-3CDSENST00000337303ENST00000296438PBRM1chr3

52592265

-FBXW12chr3

48416844

+
intron-3CDSENST00000337303ENST00000415155PBRM1chr3

52592265

-FBXW12chr3

48416844

+
intron-3CDSENST00000337303ENST00000445170PBRM1chr3

52592265

-FBXW12chr3

48416844

+
intron-5UTRENST00000337303ENST00000436231PBRM1chr3

52592265

-FBXW12chr3

48416844

+
intron-intronENST00000337303ENST00000468158PBRM1chr3

52592265

-FBXW12chr3

48416844

+
intron-3CDSENST00000410007ENST00000296438PBRM1chr3

52592265

-FBXW12chr3

48416844

+
intron-3CDSENST00000410007ENST00000415155PBRM1chr3

52592265

-FBXW12chr3

48416844

+
intron-3CDSENST00000410007ENST00000445170PBRM1chr3

52592265

-FBXW12chr3

48416844

+
intron-5UTRENST00000410007ENST00000436231PBRM1chr3

52592265

-FBXW12chr3

48416844

+
intron-intronENST00000410007ENST00000468158PBRM1chr3

52592265

-FBXW12chr3

48416844

+
intron-3CDSENST00000409057ENST00000296438PBRM1chr3

52592265

-FBXW12chr3

48416844

+
intron-3CDSENST00000409057ENST00000415155PBRM1chr3

52592265

-FBXW12chr3

48416844

+
intron-3CDSENST00000409057ENST00000445170PBRM1chr3

52592265

-FBXW12chr3

48416844

+
intron-5UTRENST00000409057ENST00000436231PBRM1chr3

52592265

-FBXW12chr3

48416844

+
intron-intronENST00000409057ENST00000468158PBRM1chr3

52592265

-FBXW12chr3

48416844

+
In-frameENST00000409114ENST00000296438PBRM1chr3

52592265

-FBXW12chr3

48416844

+
In-frameENST00000409114ENST00000415155PBRM1chr3

52592265

-FBXW12chr3

48416844

+
In-frameENST00000409114ENST00000445170PBRM1chr3

52592265

-FBXW12chr3

48416844

+
5CDS-5UTRENST00000409114ENST00000436231PBRM1chr3

52592265

-FBXW12chr3

48416844

+
5CDS-intronENST00000409114ENST00000468158PBRM1chr3

52592265

-FBXW12chr3

48416844

+
intron-3CDSENST00000409767ENST00000296438PBRM1chr3

52592265

-FBXW12chr3

48416844

+
intron-3CDSENST00000409767ENST00000415155PBRM1chr3

52592265

-FBXW12chr3

48416844

+
intron-3CDSENST00000409767ENST00000445170PBRM1chr3

52592265

-FBXW12chr3

48416844

+
intron-5UTRENST00000409767ENST00000436231PBRM1chr3

52592265

-FBXW12chr3

48416844

+
intron-intronENST00000409767ENST00000468158PBRM1chr3

52592265

-FBXW12chr3

48416844

+

Top

FusionProtFeatures for PBRM1_FBXW12


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
PBRM1

Q86U86

FBXW12

Q6X9E4

Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePBRM1chr3:52595783chr3:48416844ENST00000296302-2530630_63314291690Compositional biasNote=Poly-Asp
HgenePBRM1chr3:52595783chr3:48416844ENST00000337303-2528630_63314291583Compositional biasNote=Poly-Asp
HgenePBRM1chr3:52595783chr3:48416844ENST00000356770-2428630_63313971603Compositional biasNote=Poly-Asp
HgenePBRM1chr3:52595783chr3:48416844ENST00000394830-2630630_63313771583Compositional biasNote=Poly-Asp
HgenePBRM1chr3:52595783chr3:48416844ENST00000409057-2529630_63314291635Compositional biasNote=Poly-Asp
HgenePBRM1chr3:52595783chr3:48416844ENST00000409114-2630630_63314441653Compositional biasNote=Poly-Asp
HgenePBRM1chr3:52595783chr3:48416844ENST00000409767-2629630_63314441598Compositional biasNote=Poly-Asp
HgenePBRM1chr3:52595783chr3:48416844ENST00000410007-2529630_63314041610Compositional biasNote=Poly-Asp
HgenePBRM1chr3:52595783chr3:48416844ENST00000409114-26301379_144714441653DNA bindingHMG box
HgenePBRM1chr3:52595783chr3:48416844ENST00000409767-26291379_144714441598DNA bindingHMG box
HgenePBRM1chr3:52595783chr3:48416844ENST00000296302-25301156_127214291690DomainBAH 2
HgenePBRM1chr3:52595783chr3:48416844ENST00000296302-2530200_27014291690DomainBromo 2
HgenePBRM1chr3:52595783chr3:48416844ENST00000296302-2530400_47014291690DomainBromo 3
HgenePBRM1chr3:52595783chr3:48416844ENST00000296302-2530538_60814291690DomainBromo 4
HgenePBRM1chr3:52595783chr3:48416844ENST00000296302-253064_13414291690DomainBromo 1
HgenePBRM1chr3:52595783chr3:48416844ENST00000296302-2530676_74614291690DomainBromo 5
HgenePBRM1chr3:52595783chr3:48416844ENST00000296302-2530792_86214291690DomainBromo 6
HgenePBRM1chr3:52595783chr3:48416844ENST00000296302-2530956_107414291690DomainBAH 1
HgenePBRM1chr3:52595783chr3:48416844ENST00000337303-25281156_127214291583DomainBAH 2
HgenePBRM1chr3:52595783chr3:48416844ENST00000337303-2528200_27014291583DomainBromo 2
HgenePBRM1chr3:52595783chr3:48416844ENST00000337303-2528400_47014291583DomainBromo 3
HgenePBRM1chr3:52595783chr3:48416844ENST00000337303-2528538_60814291583DomainBromo 4
HgenePBRM1chr3:52595783chr3:48416844ENST00000337303-252864_13414291583DomainBromo 1
HgenePBRM1chr3:52595783chr3:48416844ENST00000337303-2528676_74614291583DomainBromo 5
HgenePBRM1chr3:52595783chr3:48416844ENST00000337303-2528792_86214291583DomainBromo 6
HgenePBRM1chr3:52595783chr3:48416844ENST00000337303-2528956_107414291583DomainBAH 1
HgenePBRM1chr3:52595783chr3:48416844ENST00000356770-24281156_127213971603DomainBAH 2
HgenePBRM1chr3:52595783chr3:48416844ENST00000356770-2428200_27013971603DomainBromo 2
HgenePBRM1chr3:52595783chr3:48416844ENST00000356770-2428400_47013971603DomainBromo 3
HgenePBRM1chr3:52595783chr3:48416844ENST00000356770-2428538_60813971603DomainBromo 4
HgenePBRM1chr3:52595783chr3:48416844ENST00000356770-242864_13413971603DomainBromo 1
HgenePBRM1chr3:52595783chr3:48416844ENST00000356770-2428676_74613971603DomainBromo 5
HgenePBRM1chr3:52595783chr3:48416844ENST00000356770-2428792_86213971603DomainBromo 6
HgenePBRM1chr3:52595783chr3:48416844ENST00000356770-2428956_107413971603DomainBAH 1
HgenePBRM1chr3:52595783chr3:48416844ENST00000394830-26301156_127213771583DomainBAH 2
HgenePBRM1chr3:52595783chr3:48416844ENST00000394830-2630200_27013771583DomainBromo 2
HgenePBRM1chr3:52595783chr3:48416844ENST00000394830-2630400_47013771583DomainBromo 3
HgenePBRM1chr3:52595783chr3:48416844ENST00000394830-2630538_60813771583DomainBromo 4
HgenePBRM1chr3:52595783chr3:48416844ENST00000394830-263064_13413771583DomainBromo 1
HgenePBRM1chr3:52595783chr3:48416844ENST00000394830-2630676_74613771583DomainBromo 5
HgenePBRM1chr3:52595783chr3:48416844ENST00000394830-2630792_86213771583DomainBromo 6
HgenePBRM1chr3:52595783chr3:48416844ENST00000394830-2630956_107413771583DomainBAH 1
HgenePBRM1chr3:52595783chr3:48416844ENST00000409057-25291156_127214291635DomainBAH 2
HgenePBRM1chr3:52595783chr3:48416844ENST00000409057-2529200_27014291635DomainBromo 2
HgenePBRM1chr3:52595783chr3:48416844ENST00000409057-2529400_47014291635DomainBromo 3
HgenePBRM1chr3:52595783chr3:48416844ENST00000409057-2529538_60814291635DomainBromo 4
HgenePBRM1chr3:52595783chr3:48416844ENST00000409057-252964_13414291635DomainBromo 1
HgenePBRM1chr3:52595783chr3:48416844ENST00000409057-2529676_74614291635DomainBromo 5
HgenePBRM1chr3:52595783chr3:48416844ENST00000409057-2529792_86214291635DomainBromo 6
HgenePBRM1chr3:52595783chr3:48416844ENST00000409057-2529956_107414291635DomainBAH 1
HgenePBRM1chr3:52595783chr3:48416844ENST00000409114-26301156_127214441653DomainBAH 2
HgenePBRM1chr3:52595783chr3:48416844ENST00000409114-2630200_27014441653DomainBromo 2
HgenePBRM1chr3:52595783chr3:48416844ENST00000409114-2630400_47014441653DomainBromo 3
HgenePBRM1chr3:52595783chr3:48416844ENST00000409114-2630538_60814441653DomainBromo 4
HgenePBRM1chr3:52595783chr3:48416844ENST00000409114-263064_13414441653DomainBromo 1
HgenePBRM1chr3:52595783chr3:48416844ENST00000409114-2630676_74614441653DomainBromo 5
HgenePBRM1chr3:52595783chr3:48416844ENST00000409114-2630792_86214441653DomainBromo 6
HgenePBRM1chr3:52595783chr3:48416844ENST00000409114-2630956_107414441653DomainBAH 1
HgenePBRM1chr3:52595783chr3:48416844ENST00000409767-26291156_127214441598DomainBAH 2
HgenePBRM1chr3:52595783chr3:48416844ENST00000409767-2629200_27014441598DomainBromo 2
HgenePBRM1chr3:52595783chr3:48416844ENST00000409767-2629400_47014441598DomainBromo 3
HgenePBRM1chr3:52595783chr3:48416844ENST00000409767-2629538_60814441598DomainBromo 4
HgenePBRM1chr3:52595783chr3:48416844ENST00000409767-262964_13414441598DomainBromo 1
HgenePBRM1chr3:52595783chr3:48416844ENST00000409767-2629676_74614441598DomainBromo 5
HgenePBRM1chr3:52595783chr3:48416844ENST00000409767-2629792_86214441598DomainBromo 6
HgenePBRM1chr3:52595783chr3:48416844ENST00000409767-2629956_107414441598DomainBAH 1
HgenePBRM1chr3:52595783chr3:48416844ENST00000410007-25291156_127214041610DomainBAH 2
HgenePBRM1chr3:52595783chr3:48416844ENST00000410007-2529200_27014041610DomainBromo 2
HgenePBRM1chr3:52595783chr3:48416844ENST00000410007-2529400_47014041610DomainBromo 3
HgenePBRM1chr3:52595783chr3:48416844ENST00000410007-2529538_60814041610DomainBromo 4
HgenePBRM1chr3:52595783chr3:48416844ENST00000410007-252964_13414041610DomainBromo 1
HgenePBRM1chr3:52595783chr3:48416844ENST00000410007-2529676_74614041610DomainBromo 5
HgenePBRM1chr3:52595783chr3:48416844ENST00000410007-2529792_86214041610DomainBromo 6
HgenePBRM1chr3:52595783chr3:48416844ENST00000410007-2529956_107414041610DomainBAH 1
TgeneFBXW12chr3:52595783chr3:48416844ENST00000296438+311136_17495465RepeatNote=WD 2
TgeneFBXW12chr3:52595783chr3:48416844ENST00000296438+311178_21795465RepeatNote=WD 3
TgeneFBXW12chr3:52595783chr3:48416844ENST00000296438+311222_26395465RepeatNote=WD 4
TgeneFBXW12chr3:52595783chr3:48416844ENST00000296438+311270_31595465RepeatNote=WD 5
TgeneFBXW12chr3:52595783chr3:48416844ENST00000296438+311320_36795465RepeatNote=WD 6
TgeneFBXW12chr3:52595783chr3:48416844ENST00000296438+311370_40795465RepeatNote=WD 7
TgeneFBXW12chr3:52595783chr3:48416844ENST00000296438+311416_46195465RepeatNote=WD 8
TgeneFBXW12chr3:52595783chr3:48416844ENST00000415155+310136_17495395RepeatNote=WD 2
TgeneFBXW12chr3:52595783chr3:48416844ENST00000415155+310178_21795395RepeatNote=WD 3
TgeneFBXW12chr3:52595783chr3:48416844ENST00000415155+310222_26395395RepeatNote=WD 4
TgeneFBXW12chr3:52595783chr3:48416844ENST00000415155+310270_31595395RepeatNote=WD 5
TgeneFBXW12chr3:52595783chr3:48416844ENST00000415155+310320_36795395RepeatNote=WD 6
TgeneFBXW12chr3:52595783chr3:48416844ENST00000415155+310370_40795395RepeatNote=WD 7
TgeneFBXW12chr3:52595783chr3:48416844ENST00000415155+310416_46195395RepeatNote=WD 8
TgeneFBXW12chr3:52595783chr3:48416844ENST00000445170+210136_17476446RepeatNote=WD 2
TgeneFBXW12chr3:52595783chr3:48416844ENST00000445170+210178_21776446RepeatNote=WD 3
TgeneFBXW12chr3:52595783chr3:48416844ENST00000445170+210222_26376446RepeatNote=WD 4
TgeneFBXW12chr3:52595783chr3:48416844ENST00000445170+210270_31576446RepeatNote=WD 5
TgeneFBXW12chr3:52595783chr3:48416844ENST00000445170+210320_36776446RepeatNote=WD 6
TgeneFBXW12chr3:52595783chr3:48416844ENST00000445170+210370_40776446RepeatNote=WD 7
TgeneFBXW12chr3:52595783chr3:48416844ENST00000445170+210416_46176446RepeatNote=WD 8
TgeneFBXW12chr3:52595783chr3:48416844ENST00000445170+21089_13276446RepeatNote=WD 1

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePBRM1chr3:52595783chr3:48416844ENST00000296302-25301468_159914291690Compositional biasNote=Pro-rich
HgenePBRM1chr3:52595783chr3:48416844ENST00000337303-25281468_159914291583Compositional biasNote=Pro-rich
HgenePBRM1chr3:52595783chr3:48416844ENST00000356770-24281468_159913971603Compositional biasNote=Pro-rich
HgenePBRM1chr3:52595783chr3:48416844ENST00000394830-26301468_159913771583Compositional biasNote=Pro-rich
HgenePBRM1chr3:52595783chr3:48416844ENST00000409057-25291468_159914291635Compositional biasNote=Pro-rich
HgenePBRM1chr3:52595783chr3:48416844ENST00000409114-26301468_159914441653Compositional biasNote=Pro-rich
HgenePBRM1chr3:52595783chr3:48416844ENST00000409767-26291468_159914441598Compositional biasNote=Pro-rich
HgenePBRM1chr3:52595783chr3:48416844ENST00000410007-25291468_159914041610Compositional biasNote=Pro-rich
HgenePBRM1chr3:52595783chr3:48416844ENST00000296302-25301379_144714291690DNA bindingHMG box
HgenePBRM1chr3:52595783chr3:48416844ENST00000337303-25281379_144714291583DNA bindingHMG box
HgenePBRM1chr3:52595783chr3:48416844ENST00000356770-24281379_144713971603DNA bindingHMG box
HgenePBRM1chr3:52595783chr3:48416844ENST00000394830-26301379_144713771583DNA bindingHMG box
HgenePBRM1chr3:52595783chr3:48416844ENST00000409057-25291379_144714291635DNA bindingHMG box
HgenePBRM1chr3:52595783chr3:48416844ENST00000410007-25291379_144714041610DNA bindingHMG box
TgeneFBXW12chr3:52595783chr3:48416844ENST00000296438+3111_4595465DomainF-box
TgeneFBXW12chr3:52595783chr3:48416844ENST00000415155+3101_4595395DomainF-box
TgeneFBXW12chr3:52595783chr3:48416844ENST00000445170+2101_4576446DomainF-box
TgeneFBXW12chr3:52595783chr3:48416844ENST00000296438+31189_13295465RepeatNote=WD 1
TgeneFBXW12chr3:52595783chr3:48416844ENST00000415155+31089_13295395RepeatNote=WD 1


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FusionGeneSequence for PBRM1_FBXW12


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_PBRM1_ENST00000356770_chr3_52595783_-_FBXW12_ENST00000296438_chr3_48416844_+_1767aa
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQ
PIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVF
KDANSIKKIFYMKKAEIEHHEMAKSSLRMSNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDT
VRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQA
KKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIE
HNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKL
NEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVL
HKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLFQE
HMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSE
DSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDY
YNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKN
TDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEET
EHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFR
KPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKIN
MSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEAFETELAYLSGNRLTVDEQEKSIICSVSPKQELCAWDVQEGTM
IWSSPVQEFHFSNLVTLPQMHLAITMDRKKTIKVWNCQDRDALAVLPMPQPCYCMEAYLTKDGPFLMVGDAAGDIYTFTLPGLRDVSKVT
AFQYGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLLRPSEGSVPLSTFLPHKLCASACWTPKVKNRITLMSQSSTGKKTEFITFDLTT
KKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIVFTSGPYLLLFSITGFLLQRFEDHQAAINNFWVDPCYVLTTSENSVHVYMWEE

>In-frame_PBRM1_ENST00000356770_chr3_52595783_-_FBXW12_ENST00000415155_chr3_48416844_+_1697aa
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQ
PIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVF
KDANSIKKIFYMKKAEIEHHEMAKSSLRMSNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDT
VRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQA
KKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIE
HNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKL
NEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVL
HKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLFQE
HMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSE
DSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDY
YNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKN
TDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEET
EHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFR
KPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKIN
MSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEAFETELAYLSGNRLTVDEQEKSIICSVSPKQELCAWDVQEVGD
AAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLLRPSEGSVPLSTFLPHKLCASACWTPKVKNRIT
LMSQSSTGKKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIVFTSGPYLLLFSITGFLLQRFEDHQAAINNFWV

>In-frame_PBRM1_ENST00000356770_chr3_52595783_-_FBXW12_ENST00000445170_chr3_48416844_+_1767aa
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQ
PIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVF
KDANSIKKIFYMKKAEIEHHEMAKSSLRMSNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDT
VRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQA
KKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIE
HNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKL
NEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVL
HKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLFQE
HMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSE
DSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDY
YNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKN
TDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEET
EHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFR
KPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKIN
MSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEAFETELAYLSGNRLTVDEQEKSIICSVSPKQELCAWDVQEGTM
IWSSPVQEFHFSNLVTLPQMHLAITMDRKKTIKVWNCQDRDALAVLPMPQPCYCMEAYLTKDGPFLMVGDAAGDIYTFTLPGLRDVSKVT
AFQYGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLLRPSEGSVPLSTFLPHKLCASACWTPKVKNRITLMSQSSTGKKTEFITFDLTT
KKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIVFTSGPYLLLFSITGFLLQRFEDHQAAINNFWVDPCYVLTTSENSVHVYMWEE

>In-frame_PBRM1_ENST00000296302_chr3_52595783_-_FBXW12_ENST00000296438_chr3_48416844_+_1799aa
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQ
PIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVF
KDANSIKKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLEC
DLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR
RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPD
DDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD
IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAV
DPNFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN
DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGE
KWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI
SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHG
LVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR
YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLA
SELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEAFETELAYLSG
NRLTVDEQEKSIICSVSPKQELCAWDVQEGTMIWSSPVQEFHFSNLVTLPQMHLAITMDRKKTIKVWNCQDRDALAVLPMPQPCYCMEAY
LTKDGPFLMVGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLLRPSEGSVPLSTFLPHKLCAS
ACWTPKVKNRITLMSQSSTGKKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIVFTSGPYLLLFSITGFLLQRF

>In-frame_PBRM1_ENST00000296302_chr3_52595783_-_FBXW12_ENST00000415155_chr3_48416844_+_1729aa
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQ
PIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVF
KDANSIKKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLEC
DLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR
RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPD
DDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD
IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAV
DPNFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN
DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGE
KWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI
SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHG
LVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR
YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLA
SELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEAFETELAYLSG
NRLTVDEQEKSIICSVSPKQELCAWDVQEVGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLL
RPSEGSVPLSTFLPHKLCASACWTPKVKNRITLMSQSSTGKKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIV
FTSGPYLLLFSITGFLLQRFEDHQAAINNFWVDPCYVLTTSENSVHVYMWEEGGRHPYLRSCCHLENTWHDHTTDSCISSVMCDNASIVL

>In-frame_PBRM1_ENST00000296302_chr3_52595783_-_FBXW12_ENST00000445170_chr3_48416844_+_1799aa
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQ
PIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVF
KDANSIKKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLEC
DLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR
RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPD
DDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD
IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAV
DPNFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN
DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGE
KWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI
SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHG
LVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR
YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLA
SELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEAFETELAYLSG
NRLTVDEQEKSIICSVSPKQELCAWDVQEGTMIWSSPVQEFHFSNLVTLPQMHLAITMDRKKTIKVWNCQDRDALAVLPMPQPCYCMEAY
LTKDGPFLMVGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLLRPSEGSVPLSTFLPHKLCAS
ACWTPKVKNRITLMSQSSTGKKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIVFTSGPYLLLFSITGFLLQRF

>In-frame_PBRM1_ENST00000337303_chr3_52595783_-_FBXW12_ENST00000296438_chr3_48416844_+_1799aa
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQ
PIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVF
KDANSIKKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLEC
DLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR
RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPD
DDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD
IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAV
DPNFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN
DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGE
KWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI
SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHG
LVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR
YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLA
SELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEAFETELAYLSG
NRLTVDEQEKSIICSVSPKQELCAWDVQEGTMIWSSPVQEFHFSNLVTLPQMHLAITMDRKKTIKVWNCQDRDALAVLPMPQPCYCMEAY
LTKDGPFLMVGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLLRPSEGSVPLSTFLPHKLCAS
ACWTPKVKNRITLMSQSSTGKKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIVFTSGPYLLLFSITGFLLQRF

>In-frame_PBRM1_ENST00000337303_chr3_52595783_-_FBXW12_ENST00000415155_chr3_48416844_+_1729aa
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQ
PIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVF
KDANSIKKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLEC
DLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR
RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPD
DDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD
IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAV
DPNFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN
DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGE
KWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI
SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHG
LVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR
YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLA
SELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEAFETELAYLSG
NRLTVDEQEKSIICSVSPKQELCAWDVQEVGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLL
RPSEGSVPLSTFLPHKLCASACWTPKVKNRITLMSQSSTGKKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIV
FTSGPYLLLFSITGFLLQRFEDHQAAINNFWVDPCYVLTTSENSVHVYMWEEGGRHPYLRSCCHLENTWHDHTTDSCISSVMCDNASIVL

>In-frame_PBRM1_ENST00000337303_chr3_52595783_-_FBXW12_ENST00000445170_chr3_48416844_+_1799aa
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQ
PIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVF
KDANSIKKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLEC
DLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR
RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPD
DDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD
IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAV
DPNFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN
DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGE
KWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI
SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHG
LVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR
YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLA
SELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEAFETELAYLSG
NRLTVDEQEKSIICSVSPKQELCAWDVQEGTMIWSSPVQEFHFSNLVTLPQMHLAITMDRKKTIKVWNCQDRDALAVLPMPQPCYCMEAY
LTKDGPFLMVGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLLRPSEGSVPLSTFLPHKLCAS
ACWTPKVKNRITLMSQSSTGKKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIVFTSGPYLLLFSITGFLLQRF

>In-frame_PBRM1_ENST00000410007_chr3_52595783_-_FBXW12_ENST00000296438_chr3_48416844_+_1774aa
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQ
PIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVF
KDANSIKKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLEC
DLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR
RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPD
DDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD
IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAV
DPNFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN
DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAEK
EVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANAD
KGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPI
FIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVD
DEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKE
GSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEAFETELAYLSGNRLTVDEQEKSIICSVSPKQELCAW
DVQEGTMIWSSPVQEFHFSNLVTLPQMHLAITMDRKKTIKVWNCQDRDALAVLPMPQPCYCMEAYLTKDGPFLMVGDAAGDIYTFTLPGL
RDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLLRPSEGSVPLSTFLPHKLCASACWTPKVKNRITLMSQSSTGKKTEF
ITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIVFTSGPYLLLFSITGFLLQRFEDHQAAINNFWVDPCYVLTTSENSV

>In-frame_PBRM1_ENST00000410007_chr3_52595783_-_FBXW12_ENST00000415155_chr3_48416844_+_1704aa
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQ
PIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVF
KDANSIKKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLEC
DLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR
RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPD
DDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD
IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAV
DPNFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN
DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAEK
EVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANAD
KGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPI
FIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVD
DEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKE
GSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEAFETELAYLSGNRLTVDEQEKSIICSVSPKQELCAW
DVQEVGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLLRPSEGSVPLSTFLPHKLCASACWTP
KVKNRITLMSQSSTGKKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIVFTSGPYLLLFSITGFLLQRFEDHQA

>In-frame_PBRM1_ENST00000410007_chr3_52595783_-_FBXW12_ENST00000445170_chr3_48416844_+_1774aa
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQ
PIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVF
KDANSIKKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLEC
DLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR
RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPD
DDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD
IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAV
DPNFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN
DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAEK
EVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANAD
KGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPI
FIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVD
DEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKE
GSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEAFETELAYLSGNRLTVDEQEKSIICSVSPKQELCAW
DVQEGTMIWSSPVQEFHFSNLVTLPQMHLAITMDRKKTIKVWNCQDRDALAVLPMPQPCYCMEAYLTKDGPFLMVGDAAGDIYTFTLPGL
RDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLLRPSEGSVPLSTFLPHKLCASACWTPKVKNRITLMSQSSTGKKTEF
ITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIVFTSGPYLLLFSITGFLLQRFEDHQAAINNFWVDPCYVLTTSENSV

>In-frame_PBRM1_ENST00000409057_chr3_52595783_-_FBXW12_ENST00000296438_chr3_48416844_+_1799aa
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQ
PIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVF
KDANSIKKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLEC
DLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR
RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPD
DDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD
IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAV
DPNFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN
DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGE
KWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI
SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHG
LVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR
YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLA
SELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEAFETELAYLSG
NRLTVDEQEKSIICSVSPKQELCAWDVQEGTMIWSSPVQEFHFSNLVTLPQMHLAITMDRKKTIKVWNCQDRDALAVLPMPQPCYCMEAY
LTKDGPFLMVGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLLRPSEGSVPLSTFLPHKLCAS
ACWTPKVKNRITLMSQSSTGKKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIVFTSGPYLLLFSITGFLLQRF

>In-frame_PBRM1_ENST00000409057_chr3_52595783_-_FBXW12_ENST00000415155_chr3_48416844_+_1729aa
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQ
PIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVF
KDANSIKKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLEC
DLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR
RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPD
DDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD
IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAV
DPNFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN
DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGE
KWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI
SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHG
LVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR
YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLA
SELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEAFETELAYLSG
NRLTVDEQEKSIICSVSPKQELCAWDVQEVGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLL
RPSEGSVPLSTFLPHKLCASACWTPKVKNRITLMSQSSTGKKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIV
FTSGPYLLLFSITGFLLQRFEDHQAAINNFWVDPCYVLTTSENSVHVYMWEEGGRHPYLRSCCHLENTWHDHTTDSCISSVMCDNASIVL

>In-frame_PBRM1_ENST00000409057_chr3_52595783_-_FBXW12_ENST00000445170_chr3_48416844_+_1799aa
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQ
PIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVF
KDANSIKKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLEC
DLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR
RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPD
DDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD
IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAV
DPNFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN
DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGE
KWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI
SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHG
LVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR
YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLA
SELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEAFETELAYLSG
NRLTVDEQEKSIICSVSPKQELCAWDVQEGTMIWSSPVQEFHFSNLVTLPQMHLAITMDRKKTIKVWNCQDRDALAVLPMPQPCYCMEAY
LTKDGPFLMVGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLLRPSEGSVPLSTFLPHKLCAS
ACWTPKVKNRITLMSQSSTGKKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIVFTSGPYLLLFSITGFLLQRF

>In-frame_PBRM1_ENST00000409114_chr3_52595783_-_FBXW12_ENST00000296438_chr3_48416844_+_1814aa
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQ
PIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVF
KDANSIKKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLEC
DLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKRNTHDSEMLGLRRLSSKKNIRKQRMKI
LFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILE
KLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMD
MEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDD
EGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEI
LLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQP
HIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSA
KTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYND
MWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCR
PTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSE
VIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKK
AEYEAFETELAYLSGNRLTVDEQEKSIICSVSPKQELCAWDVQEGTMIWSSPVQEFHFSNLVTLPQMHLAITMDRKKTIKVWNCQDRDAL
AVLPMPQPCYCMEAYLTKDGPFLMVGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLLRPSEG
SVPLSTFLPHKLCASACWTPKVKNRITLMSQSSTGKKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIVFTSGP
YLLLFSITGFLLQRFEDHQAAINNFWVDPCYVLTTSENSVHVYMWEEGGRHPYLRSCCHLENTWHDHTTDSCISSVMCDNASIVLRVRKV

>In-frame_PBRM1_ENST00000409114_chr3_52595783_-_FBXW12_ENST00000415155_chr3_48416844_+_1744aa
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQ
PIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVF
KDANSIKKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLEC
DLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKRNTHDSEMLGLRRLSSKKNIRKQRMKI
LFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILE
KLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMD
MEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDD
EGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEI
LLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQP
HIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSA
KTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYND
MWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCR
PTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSE
VIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKK
AEYEAFETELAYLSGNRLTVDEQEKSIICSVSPKQELCAWDVQEVGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGT
YSRTLPQVFLTESLLRPSEGSVPLSTFLPHKLCASACWTPKVKNRITLMSQSSTGKKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHL
KCPIWMGASDGYMIVFTSGPYLLLFSITGFLLQRFEDHQAAINNFWVDPCYVLTTSENSVHVYMWEEGGRHPYLRSCCHLENTWHDHTTD

>In-frame_PBRM1_ENST00000409114_chr3_52595783_-_FBXW12_ENST00000445170_chr3_48416844_+_1814aa
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQ
PIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVF
KDANSIKKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLEC
DLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKRNTHDSEMLGLRRLSSKKNIRKQRMKI
LFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILE
KLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMD
MEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDD
EGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEI
LLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQP
HIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSA
KTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYND
MWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCR
PTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSE
VIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKK
AEYEAFETELAYLSGNRLTVDEQEKSIICSVSPKQELCAWDVQEGTMIWSSPVQEFHFSNLVTLPQMHLAITMDRKKTIKVWNCQDRDAL
AVLPMPQPCYCMEAYLTKDGPFLMVGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLLRPSEG
SVPLSTFLPHKLCASACWTPKVKNRITLMSQSSTGKKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIVFTSGP
YLLLFSITGFLLQRFEDHQAAINNFWVDPCYVLTTSENSVHVYMWEEGGRHPYLRSCCHLENTWHDHTTDSCISSVMCDNASIVLRVRKV

>In-frame_PBRM1_ENST00000409767_chr3_52595783_-_FBXW12_ENST00000296438_chr3_48416844_+_1814aa
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQ
PIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVF
KDANSIKKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLEC
DLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKRNTHDSEMLGLRRLSSKKNIRKQRMKI
LFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILE
KLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMD
MEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDD
EGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEI
LLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQP
HIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSA
KTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYND
MWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCR
PTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSE
VIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKK
AEYEAFETELAYLSGNRLTVDEQEKSIICSVSPKQELCAWDVQEGTMIWSSPVQEFHFSNLVTLPQMHLAITMDRKKTIKVWNCQDRDAL
AVLPMPQPCYCMEAYLTKDGPFLMVGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLLRPSEG
SVPLSTFLPHKLCASACWTPKVKNRITLMSQSSTGKKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIVFTSGP
YLLLFSITGFLLQRFEDHQAAINNFWVDPCYVLTTSENSVHVYMWEEGGRHPYLRSCCHLENTWHDHTTDSCISSVMCDNASIVLRVRKV

>In-frame_PBRM1_ENST00000409767_chr3_52595783_-_FBXW12_ENST00000415155_chr3_48416844_+_1744aa
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQ
PIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVF
KDANSIKKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLEC
DLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKRNTHDSEMLGLRRLSSKKNIRKQRMKI
LFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILE
KLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMD
MEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDD
EGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEI
LLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQP
HIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSA
KTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYND
MWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCR
PTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSE
VIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKK
AEYEAFETELAYLSGNRLTVDEQEKSIICSVSPKQELCAWDVQEVGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGT
YSRTLPQVFLTESLLRPSEGSVPLSTFLPHKLCASACWTPKVKNRITLMSQSSTGKKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHL
KCPIWMGASDGYMIVFTSGPYLLLFSITGFLLQRFEDHQAAINNFWVDPCYVLTTSENSVHVYMWEEGGRHPYLRSCCHLENTWHDHTTD

>In-frame_PBRM1_ENST00000409767_chr3_52595783_-_FBXW12_ENST00000445170_chr3_48416844_+_1814aa
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQ
PIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVF
KDANSIKKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLEC
DLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKRNTHDSEMLGLRRLSSKKNIRKQRMKI
LFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILE
KLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMD
MEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDD
EGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEI
LLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQP
HIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSA
KTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYND
MWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCR
PTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSE
VIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKK
AEYEAFETELAYLSGNRLTVDEQEKSIICSVSPKQELCAWDVQEGTMIWSSPVQEFHFSNLVTLPQMHLAITMDRKKTIKVWNCQDRDAL
AVLPMPQPCYCMEAYLTKDGPFLMVGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLLRPSEG
SVPLSTFLPHKLCASACWTPKVKNRITLMSQSSTGKKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIVFTSGP
YLLLFSITGFLLQRFEDHQAAINNFWVDPCYVLTTSENSVHVYMWEEGGRHPYLRSCCHLENTWHDHTTDSCISSVMCDNASIVLRVRKV

>In-frame_PBRM1_ENST00000296302_chr3_52592265_-_FBXW12_ENST00000296438_chr3_48416844_+_1854aa
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQ
PIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVF
KDANSIKKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLEC
DLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR
RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPD
DDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD
IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAV
DPNFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN
DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGE
KWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI
SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHG
LVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR
YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLA
SELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEERAAKVAEQQE
RERAAQQQQPSASPRAGTPVGALMGVVPPPTPMGMLNQQLTPVAAFETELAYLSGNRLTVDEQEKSIICSVSPKQELCAWDVQEGTMIWS
SPVQEFHFSNLVTLPQMHLAITMDRKKTIKVWNCQDRDALAVLPMPQPCYCMEAYLTKDGPFLMVGDAAGDIYTFTLPGLRDVSKVTAFQ
YGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLLRPSEGSVPLSTFLPHKLCASACWTPKVKNRITLMSQSSTGKKTEFITFDLTTKKT
GGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIVFTSGPYLLLFSITGFLLQRFEDHQAAINNFWVDPCYVLTTSENSVHVYMWEEGGR

>In-frame_PBRM1_ENST00000296302_chr3_52592265_-_FBXW12_ENST00000415155_chr3_48416844_+_1784aa
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQ
PIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVF
KDANSIKKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLEC
DLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR
RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPD
DDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD
IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAV
DPNFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN
DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGE
KWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI
SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHG
LVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR
YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLA
SELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEERAAKVAEQQE
RERAAQQQQPSASPRAGTPVGALMGVVPPPTPMGMLNQQLTPVAAFETELAYLSGNRLTVDEQEKSIICSVSPKQELCAWDVQEVGDAAG
DIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLLRPSEGSVPLSTFLPHKLCASACWTPKVKNRITLMS
QSSTGKKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIVFTSGPYLLLFSITGFLLQRFEDHQAAINNFWVDPC

>In-frame_PBRM1_ENST00000296302_chr3_52592265_-_FBXW12_ENST00000445170_chr3_48416844_+_1854aa
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQ
PIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVF
KDANSIKKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLEC
DLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR
RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPD
DDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD
IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAV
DPNFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN
DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGE
KWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI
SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHG
LVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR
YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLA
SELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEERAAKVAEQQE
RERAAQQQQPSASPRAGTPVGALMGVVPPPTPMGMLNQQLTPVAAFETELAYLSGNRLTVDEQEKSIICSVSPKQELCAWDVQEGTMIWS
SPVQEFHFSNLVTLPQMHLAITMDRKKTIKVWNCQDRDALAVLPMPQPCYCMEAYLTKDGPFLMVGDAAGDIYTFTLPGLRDVSKVTAFQ
YGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLLRPSEGSVPLSTFLPHKLCASACWTPKVKNRITLMSQSSTGKKTEFITFDLTTKKT
GGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIVFTSGPYLLLFSITGFLLQRFEDHQAAINNFWVDPCYVLTTSENSVHVYMWEEGGR

>In-frame_PBRM1_ENST00000409114_chr3_52592265_-_FBXW12_ENST00000296438_chr3_48416844_+_1869aa
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQ
PIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVF
KDANSIKKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLEC
DLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKRNTHDSEMLGLRRLSSKKNIRKQRMKI
LFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILE
KLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMD
MEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDD
EGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEI
LLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQP
HIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSA
KTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYND
MWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCR
PTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSE
VIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKK
AEYEERAAKVAEQQERERAAQQQQPSASPRAGTPVGALMGVVPPPTPMGMLNQQLTPVAAFETELAYLSGNRLTVDEQEKSIICSVSPKQ
ELCAWDVQEGTMIWSSPVQEFHFSNLVTLPQMHLAITMDRKKTIKVWNCQDRDALAVLPMPQPCYCMEAYLTKDGPFLMVGDAAGDIYTF
TLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLLRPSEGSVPLSTFLPHKLCASACWTPKVKNRITLMSQSSTG
KKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIVFTSGPYLLLFSITGFLLQRFEDHQAAINNFWVDPCYVLTT

>In-frame_PBRM1_ENST00000409114_chr3_52592265_-_FBXW12_ENST00000415155_chr3_48416844_+_1799aa
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQ
PIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVF
KDANSIKKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLEC
DLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKRNTHDSEMLGLRRLSSKKNIRKQRMKI
LFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILE
KLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMD
MEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDD
EGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEI
LLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQP
HIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSA
KTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYND
MWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCR
PTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSE
VIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKK
AEYEERAAKVAEQQERERAAQQQQPSASPRAGTPVGALMGVVPPPTPMGMLNQQLTPVAAFETELAYLSGNRLTVDEQEKSIICSVSPKQ
ELCAWDVQEVGDAAGDIYTFTLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLLRPSEGSVPLSTFLPHKLCAS
ACWTPKVKNRITLMSQSSTGKKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIVFTSGPYLLLFSITGFLLQRF

>In-frame_PBRM1_ENST00000409114_chr3_52592265_-_FBXW12_ENST00000445170_chr3_48416844_+_1869aa
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQ
PIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVF
KDANSIKKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLEC
DLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKRNTHDSEMLGLRRLSSKKNIRKQRMKI
LFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILE
KLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMD
MEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDD
EGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEI
LLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQP
HIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSA
KTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYND
MWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCR
PTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSE
VIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKK
AEYEERAAKVAEQQERERAAQQQQPSASPRAGTPVGALMGVVPPPTPMGMLNQQLTPVAAFETELAYLSGNRLTVDEQEKSIICSVSPKQ
ELCAWDVQEGTMIWSSPVQEFHFSNLVTLPQMHLAITMDRKKTIKVWNCQDRDALAVLPMPQPCYCMEAYLTKDGPFLMVGDAAGDIYTF
TLPGLRDVSKVTAFQYGIVLLHCSPDKKWVFACGTYSRTLPQVFLTESLLRPSEGSVPLSTFLPHKLCASACWTPKVKNRITLMSQSSTG
KKTEFITFDLTTKKTGGQTVIQAYEIASFQVAAHLKCPIWMGASDGYMIVFTSGPYLLLFSITGFLLQRFEDHQAAINNFWVDPCYVLTT


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_PBRM1_ENST00000356770_chr3_52595783_-_FBXW12_ENST00000296438_chr3_48416844_+_5301nt
ATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAGGC
CCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACTAT
AAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCTCAG
CCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTTTTT
AACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAATGAG
TTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCAGCT
TACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAGAAA
CTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAATGGA
AGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTATTC
AAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATGAGT
AATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCTGCTTTAGCT
GCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTTTATGACACA
GTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGATTATTACCAG
CAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGTGTGATCTG
AATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTATGCAGGCA
AAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTGCCAAAAGA
AAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGAAGACTT
TGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATAATTGAG
CATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTATAATGAG
GAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGATGATGAT
GACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAGAAACTA
AATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGATCTGAG
TTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGATATTGAC
TCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTTGTTCTA
CACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAGCTTATC
CACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTGGATCCC
AACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTTCAAGAG
CATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAGTTTTTT
ATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAATGATGTG
GAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAGAGTGAA
GATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTTGGAGAT
TACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAAAAATGG
TTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGTGACTAT
TACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAACTTCCGA
GATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATCAGCTCA
GTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAGAAGAAT
ACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAATGGTGAA
CCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGCCTGGTG
CGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAAGAAACA
GAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTCGGAAAG
TGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGCTACAAT
GAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTACTTCAGA
AAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAAGGTGGA
GATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCCAGTGAG
CTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAAATCAAC
ATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGCCGCCTG
GTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGCATTTGAGACGGAGTTGGCTTATCTCTCAGGAAATAGA
CTTACAGTGGATGAACAGGAGAAATCAATCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGGTACCATG
ATCTGGTCAAGCCCAGTCCAGGAGTTCCATTTCTCAAATCTGGTAACCCTCCCTCAGATGCATCTCGCCATCACTATGGATCGGAAAAAA
ACTATCAAAGTGTGGAACTGTCAGGACAGGGACGCTCTGGCTGTTCTCCCCATGCCACAGCCCTGTTATTGCATGGAAGCCTATCTTACA
AAGGATGGCCCATTCCTGATGGTTGGCGATGCTGCAGGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAAGTTACT
GCATTTCAATATGGTATTGTACTTCTACACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTGCCACAG
GTATTCCTCACAGAGTCCTTACTGAGACCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGCGCCTGC
TGGACCCCAAAGGTGAAAAACAGGATAACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTAACAACC
AAGAAGACTGGAGGCCAAACAGTCATCCAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGGATGGGA
GCCAGTGATGGATATATGATTGTCTTTACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTTGAGGAC
CATCAGGCAGCCATCAACAACTTCTGGGTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGGGAAGAA
GGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCACCTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGTGTGATG

>In-frame_PBRM1_ENST00000356770_chr3_52595783_-_FBXW12_ENST00000415155_chr3_48416844_+_5091nt
ATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAGGC
CCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACTAT
AAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCTCAG
CCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTTTTT
AACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAATGAG
TTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCAGCT
TACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAGAAA
CTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAATGGA
AGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTATTC
AAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATGAGT
AATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCTGCTTTAGCT
GCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTTTATGACACA
GTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGATTATTACCAG
CAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGTGTGATCTG
AATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTATGCAGGCA
AAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTGCCAAAAGA
AAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGAAGACTT
TGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATAATTGAG
CATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTATAATGAG
GAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGATGATGAT
GACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAGAAACTA
AATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGATCTGAG
TTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGATATTGAC
TCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTTGTTCTA
CACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAGCTTATC
CACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTGGATCCC
AACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTTCAAGAG
CATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAGTTTTTT
ATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAATGATGTG
GAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAGAGTGAA
GATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTTGGAGAT
TACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAAAAATGG
TTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGTGACTAT
TACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAACTTCCGA
GATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATCAGCTCA
GTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAGAAGAAT
ACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAATGGTGAA
CCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGCCTGGTG
CGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAAGAAACA
GAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTCGGAAAG
TGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGCTACAAT
GAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTACTTCAGA
AAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAAGGTGGA
GATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCCAGTGAG
CTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAAATCAAC
ATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGCCGCCTG
GTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGCATTTGAGACGGAGTTGGCTTATCTCTCAGGAAATAGA
CTTACAGTGGATGAACAGGAGAAATCAATCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGTTGGCGAT
GCTGCAGGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTACTTCTACAC
TGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTGCCACAGGTATTCCTCACAGAGTCCTTACTGAGACCA
TCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACA
CTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTAACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAA
GCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATTGTCTTTACC
AGTGGACCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTTGAGGACCATCAGGCAGCCATCAACAACTTCTGGGTG
GATCCTTGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGC
TGTCACCTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGTGTGATGTGTGATAATGCAAGCATAGTACTTAGGGTG

>In-frame_PBRM1_ENST00000356770_chr3_52595783_-_FBXW12_ENST00000445170_chr3_48416844_+_5301nt
ATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAGGC
CCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACTAT
AAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCTCAG
CCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTTTTT
AACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAATGAG
TTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCAGCT
TACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAGAAA
CTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAATGGA
AGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTATTC
AAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATGAGT
AATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCTGCTTTAGCT
GCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTTTATGACACA
GTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGATTATTACCAG
CAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGTGTGATCTG
AATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTATGCAGGCA
AAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTGCCAAAAGA
AAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGAAGACTT
TGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATAATTGAG
CATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTATAATGAG
GAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGATGATGAT
GACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAGAAACTA
AATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGATCTGAG
TTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGATATTGAC
TCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTTGTTCTA
CACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAGCTTATC
CACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTGGATCCC
AACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTTCAAGAG
CATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAGTTTTTT
ATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAATGATGTG
GAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAGAGTGAA
GATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTTGGAGAT
TACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAAAAATGG
TTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGTGACTAT
TACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAACTTCCGA
GATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATCAGCTCA
GTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAGAAGAAT
ACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAATGGTGAA
CCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGCCTGGTG
CGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAAGAAACA
GAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTCGGAAAG
TGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGCTACAAT
GAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTACTTCAGA
AAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAAGGTGGA
GATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCCAGTGAG
CTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAAATCAAC
ATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGCCGCCTG
GTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGCATTTGAGACGGAGTTGGCTTATCTCTCAGGAAATAGA
CTTACAGTGGATGAACAGGAGAAATCAATCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGGTACCATG
ATCTGGTCAAGCCCAGTCCAGGAGTTCCATTTCTCAAATCTGGTAACCCTCCCTCAGATGCATCTCGCCATCACTATGGATCGGAAAAAA
ACTATCAAAGTGTGGAACTGTCAGGACAGGGACGCTCTGGCTGTTCTCCCCATGCCACAGCCCTGTTATTGCATGGAAGCCTATCTTACA
AAGGATGGCCCATTCCTGATGGTTGGCGATGCTGCAGGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAAGTTACT
GCATTTCAATATGGTATTGTACTTCTACACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTGCCACAG
GTATTCCTCACAGAGTCCTTACTGAGACCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGCGCCTGC
TGGACCCCAAAGGTGAAAAACAGGATAACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTAACAACC
AAGAAGACTGGAGGCCAAACAGTCATCCAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGGATGGGA
GCCAGTGATGGATATATGATTGTCTTTACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTTGAGGAC
CATCAGGCAGCCATCAACAACTTCTGGGTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGGGAAGAA
GGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCACCTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGTGTGATG

>In-frame_PBRM1_ENST00000296302_chr3_52595783_-_FBXW12_ENST00000296438_chr3_48416844_+_5397nt
ATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAGGC
CCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACTAT
AAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCTCAG
CCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTTTTT
AACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAATGAG
TTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCAGCT
TACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAGAAA
CTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAATGGA
AGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTATTC
AAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATGAGG
ACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAGTAT
TACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCTGCT
TTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTTTAT
GACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGATTAT
TACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGTGT
GATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTATG
CAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTGCC
AAAAGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGA
AGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATA
ATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTAT
AATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGAT
GATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAG
AAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGA
TCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGAT
ATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTT
GTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAG
CTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTG
GATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTT
CAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAG
TTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAAT
GATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAG
AGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTT
GGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAA
AAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGT
GACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAAC
TTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATC
AGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAG
AAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAAT
GGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGC
CTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAA
GAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTC
GGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGC
TACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTAC
TTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAA
GGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCC
AGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAA
ATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGC
CGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGCATTTGAGACGGAGTTGGCTTATCTCTCAGGA
AATAGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGGT
ACCATGATCTGGTCAAGCCCAGTCCAGGAGTTCCATTTCTCAAATCTGGTAACCCTCCCTCAGATGCATCTCGCCATCACTATGGATCGG
AAAAAAACTATCAAAGTGTGGAACTGTCAGGACAGGGACGCTCTGGCTGTTCTCCCCATGCCACAGCCCTGTTATTGCATGGAAGCCTAT
CTTACAAAGGATGGCCCATTCCTGATGGTTGGCGATGCTGCAGGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAA
GTTACTGCATTTCAATATGGTATTGTACTTCTACACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTG
CCACAGGTATTCCTCACAGAGTCCTTACTGAGACCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGC
GCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTA
ACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGG
ATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTT
GAGGACCATCAGGCAGCCATCAACAACTTCTGGGTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGG
GAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCACCTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGT

>In-frame_PBRM1_ENST00000296302_chr3_52595783_-_FBXW12_ENST00000415155_chr3_48416844_+_5187nt
ATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAGGC
CCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACTAT
AAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCTCAG
CCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTTTTT
AACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAATGAG
TTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCAGCT
TACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAGAAA
CTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAATGGA
AGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTATTC
AAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATGAGG
ACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAGTAT
TACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCTGCT
TTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTTTAT
GACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGATTAT
TACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGTGT
GATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTATG
CAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTGCC
AAAAGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGA
AGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATA
ATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTAT
AATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGAT
GATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAG
AAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGA
TCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGAT
ATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTT
GTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAG
CTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTG
GATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTT
CAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAG
TTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAAT
GATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAG
AGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTT
GGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAA
AAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGT
GACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAAC
TTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATC
AGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAG
AAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAAT
GGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGC
CTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAA
GAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTC
GGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGC
TACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTAC
TTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAA
GGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCC
AGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAA
ATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGC
CGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGCATTTGAGACGGAGTTGGCTTATCTCTCAGGA
AATAGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGTT
GGCGATGCTGCAGGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTACTT
CTACACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTGCCACAGGTATTCCTCACAGAGTCCTTACTG
AGACCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAACAGG
ATAACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTAACAACCAAGAAGACTGGAGGCCAAACAGTC
ATCCAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATTGTC
TTTACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTTGAGGACCATCAGGCAGCCATCAACAACTTC
TGGGTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTCAGG
AGCTGCTGTCACCTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGTGTGATGTGTGATAATGCAAGCATAGTACTT

>In-frame_PBRM1_ENST00000296302_chr3_52595783_-_FBXW12_ENST00000445170_chr3_48416844_+_5397nt
ATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAGGC
CCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACTAT
AAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCTCAG
CCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTTTTT
AACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAATGAG
TTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCAGCT
TACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAGAAA
CTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAATGGA
AGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTATTC
AAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATGAGG
ACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAGTAT
TACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCTGCT
TTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTTTAT
GACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGATTAT
TACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGTGT
GATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTATG
CAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTGCC
AAAAGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGA
AGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATA
ATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTAT
AATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGAT
GATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAG
AAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGA
TCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGAT
ATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTT
GTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAG
CTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTG
GATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTT
CAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAG
TTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAAT
GATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAG
AGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTT
GGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAA
AAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGT
GACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAAC
TTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATC
AGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAG
AAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAAT
GGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGC
CTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAA
GAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTC
GGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGC
TACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTAC
TTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAA
GGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCC
AGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAA
ATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGC
CGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGCATTTGAGACGGAGTTGGCTTATCTCTCAGGA
AATAGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGGT
ACCATGATCTGGTCAAGCCCAGTCCAGGAGTTCCATTTCTCAAATCTGGTAACCCTCCCTCAGATGCATCTCGCCATCACTATGGATCGG
AAAAAAACTATCAAAGTGTGGAACTGTCAGGACAGGGACGCTCTGGCTGTTCTCCCCATGCCACAGCCCTGTTATTGCATGGAAGCCTAT
CTTACAAAGGATGGCCCATTCCTGATGGTTGGCGATGCTGCAGGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAA
GTTACTGCATTTCAATATGGTATTGTACTTCTACACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTG
CCACAGGTATTCCTCACAGAGTCCTTACTGAGACCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGC
GCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTA
ACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGG
ATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTT
GAGGACCATCAGGCAGCCATCAACAACTTCTGGGTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGG
GAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCACCTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGT

>In-frame_PBRM1_ENST00000337303_chr3_52595783_-_FBXW12_ENST00000296438_chr3_48416844_+_5397nt
ATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAGGC
CCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACTAT
AAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCTCAG
CCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTTTTT
AACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAATGAG
TTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCAGCT
TACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAGAAA
CTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAATGGA
AGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTATTC
AAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATGAGG
ACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAGTAT
TACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCTGCT
TTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTTTAT
GACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGATTAT
TACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGTGT
GATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTATG
CAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTGCC
AAAAGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGA
AGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATA
ATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTAT
AATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGAT
GATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAG
AAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGA
TCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGAT
ATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTT
GTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAG
CTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTG
GATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTT
CAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAG
TTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAAT
GATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAG
AGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTT
GGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAA
AAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGT
GACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAAC
TTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATC
AGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAG
AAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAAT
GGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGC
CTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAA
GAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTC
GGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGC
TACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTAC
TTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAA
GGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCC
AGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAA
ATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGC
CGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGCATTTGAGACGGAGTTGGCTTATCTCTCAGGA
AATAGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGGT
ACCATGATCTGGTCAAGCCCAGTCCAGGAGTTCCATTTCTCAAATCTGGTAACCCTCCCTCAGATGCATCTCGCCATCACTATGGATCGG
AAAAAAACTATCAAAGTGTGGAACTGTCAGGACAGGGACGCTCTGGCTGTTCTCCCCATGCCACAGCCCTGTTATTGCATGGAAGCCTAT
CTTACAAAGGATGGCCCATTCCTGATGGTTGGCGATGCTGCAGGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAA
GTTACTGCATTTCAATATGGTATTGTACTTCTACACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTG
CCACAGGTATTCCTCACAGAGTCCTTACTGAGACCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGC
GCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTA
ACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGG
ATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTT
GAGGACCATCAGGCAGCCATCAACAACTTCTGGGTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGG
GAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCACCTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGT

>In-frame_PBRM1_ENST00000337303_chr3_52595783_-_FBXW12_ENST00000415155_chr3_48416844_+_5187nt
ATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAGGC
CCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACTAT
AAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCTCAG
CCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTTTTT
AACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAATGAG
TTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCAGCT
TACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAGAAA
CTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAATGGA
AGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTATTC
AAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATGAGG
ACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAGTAT
TACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCTGCT
TTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTTTAT
GACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGATTAT
TACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGTGT
GATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTATG
CAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTGCC
AAAAGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGA
AGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATA
ATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTAT
AATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGAT
GATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAG
AAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGA
TCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGAT
ATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTT
GTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAG
CTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTG
GATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTT
CAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAG
TTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAAT
GATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAG
AGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTT
GGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAA
AAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGT
GACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAAC
TTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATC
AGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAG
AAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAAT
GGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGC
CTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAA
GAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTC
GGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGC
TACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTAC
TTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAA
GGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCC
AGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAA
ATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGC
CGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGCATTTGAGACGGAGTTGGCTTATCTCTCAGGA
AATAGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGTT
GGCGATGCTGCAGGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTACTT
CTACACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTGCCACAGGTATTCCTCACAGAGTCCTTACTG
AGACCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAACAGG
ATAACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTAACAACCAAGAAGACTGGAGGCCAAACAGTC
ATCCAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATTGTC
TTTACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTTGAGGACCATCAGGCAGCCATCAACAACTTC
TGGGTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTCAGG
AGCTGCTGTCACCTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGTGTGATGTGTGATAATGCAAGCATAGTACTT

>In-frame_PBRM1_ENST00000337303_chr3_52595783_-_FBXW12_ENST00000445170_chr3_48416844_+_5397nt
ATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAGGC
CCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACTAT
AAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCTCAG
CCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTTTTT
AACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAATGAG
TTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCAGCT
TACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAGAAA
CTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAATGGA
AGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTATTC
AAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATGAGG
ACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAGTAT
TACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCTGCT
TTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTTTAT
GACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGATTAT
TACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGTGT
GATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTATG
CAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTGCC
AAAAGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGA
AGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATA
ATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTAT
AATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGAT
GATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAG
AAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGA
TCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGAT
ATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTT
GTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAG
CTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTG
GATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTT
CAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAG
TTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAAT
GATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAG
AGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTT
GGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAA
AAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGT
GACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAAC
TTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATC
AGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAG
AAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAAT
GGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGC
CTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAA
GAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTC
GGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGC
TACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTAC
TTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAA
GGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCC
AGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAA
ATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGC
CGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGCATTTGAGACGGAGTTGGCTTATCTCTCAGGA
AATAGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGGT
ACCATGATCTGGTCAAGCCCAGTCCAGGAGTTCCATTTCTCAAATCTGGTAACCCTCCCTCAGATGCATCTCGCCATCACTATGGATCGG
AAAAAAACTATCAAAGTGTGGAACTGTCAGGACAGGGACGCTCTGGCTGTTCTCCCCATGCCACAGCCCTGTTATTGCATGGAAGCCTAT
CTTACAAAGGATGGCCCATTCCTGATGGTTGGCGATGCTGCAGGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAA
GTTACTGCATTTCAATATGGTATTGTACTTCTACACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTG
CCACAGGTATTCCTCACAGAGTCCTTACTGAGACCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGC
GCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTA
ACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGG
ATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTT
GAGGACCATCAGGCAGCCATCAACAACTTCTGGGTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGG
GAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCACCTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGT

>In-frame_PBRM1_ENST00000410007_chr3_52595783_-_FBXW12_ENST00000296438_chr3_48416844_+_5322nt
ATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAGGC
CCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACTAT
AAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCTCAG
CCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTTTTT
AACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAATGAG
TTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCAGCT
TACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAGAAA
CTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAATGGA
AGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTATTC
AAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATGAGG
ACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAGTAT
TACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCTGCT
TTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTTTAT
GACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGATTAT
TACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGTGT
GATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTATG
CAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTGCC
AAAAGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGA
AGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATA
ATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTAT
AATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGAT
GATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAG
AAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGA
TCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGAT
ATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTT
GTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAG
CTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTG
GATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTT
CAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAG
TTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAAT
GATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAG
AGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTT
GGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGAAAAA
GAAGTTTTTAAGAGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAG
TTATGCCCAGAAAACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTG
TGGACCATGCCCATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGAT
AAAGGTGATGATGAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCT
GTGGAAATGTCCAATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTC
ATCAAGTCCCATGGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATC
TTCATTCACCCAGAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCC
ATGACATGTATTCTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTG
CTTTGTGAGAGCCGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGAT
GATGAAATTTACTACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAA
TTTGCCGAGTTAGAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTT
CAGACCCCCCTGGCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAA
GGCTCCAAACGGAAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCT
TTCGGGGAGCTCAGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGCATTTGAGACGGAGTTG
GCTTATCTCTCAGGAAATAGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGG
GATGTGCAAGAGGGTACCATGATCTGGTCAAGCCCAGTCCAGGAGTTCCATTTCTCAAATCTGGTAACCCTCCCTCAGATGCATCTCGCC
ATCACTATGGATCGGAAAAAAACTATCAAAGTGTGGAACTGTCAGGACAGGGACGCTCTGGCTGTTCTCCCCATGCCACAGCCCTGTTAT
TGCATGGAAGCCTATCTTACAAAGGATGGCCCATTCCTGATGGTTGGCGATGCTGCAGGTGACATCTACACATTTACACTGCCTGGGTTA
AGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTACTTCTACACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGGACA
TACAGTCGTACCTTGCCACAGGTATTCCTCACAGAGTCCTTACTGAGACCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACAT
AAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTT
ATCACCTTTGATCTAACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTG
AAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGCTTC
CTGCTGCAACGATTTGAGGACCATCAGGCAGCCATCAACAACTTCTGGGTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCTGTG
CACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCACCTGGAAAACACGTGGCATGATCACACAACAGAC
AGCTGCATCTCCAGTGTGATGTGTGATAATGCAAGCATAGTACTTAGGGTGAGGAAAGTAAGTGACTCCAGCATTCTGGTGATGTATTCT

>In-frame_PBRM1_ENST00000410007_chr3_52595783_-_FBXW12_ENST00000415155_chr3_48416844_+_5112nt
ATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAGGC
CCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACTAT
AAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCTCAG
CCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTTTTT
AACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAATGAG
TTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCAGCT
TACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAGAAA
CTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAATGGA
AGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTATTC
AAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATGAGG
ACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAGTAT
TACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCTGCT
TTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTTTAT
GACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGATTAT
TACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGTGT
GATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTATG
CAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTGCC
AAAAGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGA
AGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATA
ATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTAT
AATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGAT
GATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAG
AAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGA
TCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGAT
ATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTT
GTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAG
CTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTG
GATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTT
CAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAG
TTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAAT
GATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAG
AGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTT
GGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGAAAAA
GAAGTTTTTAAGAGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAG
TTATGCCCAGAAAACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTG
TGGACCATGCCCATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGAT
AAAGGTGATGATGAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCT
GTGGAAATGTCCAATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTC
ATCAAGTCCCATGGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATC
TTCATTCACCCAGAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCC
ATGACATGTATTCTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTG
CTTTGTGAGAGCCGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGAT
GATGAAATTTACTACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAA
TTTGCCGAGTTAGAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTT
CAGACCCCCCTGGCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAA
GGCTCCAAACGGAAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCT
TTCGGGGAGCTCAGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGCATTTGAGACGGAGTTG
GCTTATCTCTCAGGAAATAGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGG
GATGTGCAAGAGGTTGGCGATGCTGCAGGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAAGTTACTGCATTTCAA
TATGGTATTGTACTTCTACACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTGCCACAGGTATTCCTC
ACAGAGTCCTTACTGAGACCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGCGCCTGCTGGACCCCA
AAGGTGAAAAACAGGATAACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTAACAACCAAGAAGACT
GGAGGCCAAACAGTCATCCAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGGATGGGAGCCAGTGAT
GGATATATGATTGTCTTTACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTTGAGGACCATCAGGCA
GCCATCAACAACTTCTGGGTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGGGAAGAAGGAGGCCGC
CATCCATACCTCAGGAGCTGCTGTCACCTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGTGTGATGTGTGATAAT

>In-frame_PBRM1_ENST00000410007_chr3_52595783_-_FBXW12_ENST00000445170_chr3_48416844_+_5322nt
ATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAGGC
CCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACTAT
AAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCTCAG
CCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTTTTT
AACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAATGAG
TTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCAGCT
TACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAGAAA
CTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAATGGA
AGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTATTC
AAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATGAGG
ACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAGTAT
TACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCTGCT
TTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTTTAT
GACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGATTAT
TACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGTGT
GATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTATG
CAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTGCC
AAAAGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGA
AGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATA
ATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTAT
AATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGAT
GATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAG
AAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGA
TCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGAT
ATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTT
GTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAG
CTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTG
GATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTT
CAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAG
TTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAAT
GATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAG
AGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTT
GGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGAAAAA
GAAGTTTTTAAGAGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAG
TTATGCCCAGAAAACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTG
TGGACCATGCCCATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGAT
AAAGGTGATGATGAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCT
GTGGAAATGTCCAATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTC
ATCAAGTCCCATGGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATC
TTCATTCACCCAGAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCC
ATGACATGTATTCTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTG
CTTTGTGAGAGCCGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGAT
GATGAAATTTACTACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAA
TTTGCCGAGTTAGAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTT
CAGACCCCCCTGGCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAA
GGCTCCAAACGGAAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCT
TTCGGGGAGCTCAGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGCATTTGAGACGGAGTTG
GCTTATCTCTCAGGAAATAGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGG
GATGTGCAAGAGGGTACCATGATCTGGTCAAGCCCAGTCCAGGAGTTCCATTTCTCAAATCTGGTAACCCTCCCTCAGATGCATCTCGCC
ATCACTATGGATCGGAAAAAAACTATCAAAGTGTGGAACTGTCAGGACAGGGACGCTCTGGCTGTTCTCCCCATGCCACAGCCCTGTTAT
TGCATGGAAGCCTATCTTACAAAGGATGGCCCATTCCTGATGGTTGGCGATGCTGCAGGTGACATCTACACATTTACACTGCCTGGGTTA
AGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTACTTCTACACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGGACA
TACAGTCGTACCTTGCCACAGGTATTCCTCACAGAGTCCTTACTGAGACCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACAT
AAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTT
ATCACCTTTGATCTAACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTG
AAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGCTTC
CTGCTGCAACGATTTGAGGACCATCAGGCAGCCATCAACAACTTCTGGGTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCTGTG
CACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCACCTGGAAAACACGTGGCATGATCACACAACAGAC
AGCTGCATCTCCAGTGTGATGTGTGATAATGCAAGCATAGTACTTAGGGTGAGGAAAGTAAGTGACTCCAGCATTCTGGTGATGTATTCT

>In-frame_PBRM1_ENST00000409057_chr3_52595783_-_FBXW12_ENST00000296438_chr3_48416844_+_5397nt
ATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAGGC
CCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACTAT
AAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCTCAG
CCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTTTTT
AACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAATGAG
TTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCAGCT
TACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAGAAA
CTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAATGGA
AGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTATTC
AAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATGAGG
ACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAGTAT
TACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCTGCT
TTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTTTAT
GACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGATTAT
TACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGTGT
GATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTATG
CAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTGCC
AAAAGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGA
AGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATA
ATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTAT
AATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGAT
GATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAG
AAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGA
TCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGAT
ATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTT
GTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAG
CTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTG
GATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTT
CAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAG
TTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAAT
GATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAG
AGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTT
GGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAA
AAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGT
GACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAAC
TTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATC
AGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAG
AAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAAT
GGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGC
CTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAA
GAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTC
GGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGC
TACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTAC
TTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAA
GGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCC
AGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAA
ATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGC
CGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGCATTTGAGACGGAGTTGGCTTATCTCTCAGGA
AATAGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGGT
ACCATGATCTGGTCAAGCCCAGTCCAGGAGTTCCATTTCTCAAATCTGGTAACCCTCCCTCAGATGCATCTCGCCATCACTATGGATCGG
AAAAAAACTATCAAAGTGTGGAACTGTCAGGACAGGGACGCTCTGGCTGTTCTCCCCATGCCACAGCCCTGTTATTGCATGGAAGCCTAT
CTTACAAAGGATGGCCCATTCCTGATGGTTGGCGATGCTGCAGGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAA
GTTACTGCATTTCAATATGGTATTGTACTTCTACACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTG
CCACAGGTATTCCTCACAGAGTCCTTACTGAGACCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGC
GCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTA
ACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGG
ATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTT
GAGGACCATCAGGCAGCCATCAACAACTTCTGGGTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGG
GAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCACCTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGT

>In-frame_PBRM1_ENST00000409057_chr3_52595783_-_FBXW12_ENST00000415155_chr3_48416844_+_5187nt
ATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAGGC
CCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACTAT
AAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCTCAG
CCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTTTTT
AACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAATGAG
TTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCAGCT
TACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAGAAA
CTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAATGGA
AGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTATTC
AAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATGAGG
ACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAGTAT
TACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCTGCT
TTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTTTAT
GACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGATTAT
TACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGTGT
GATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTATG
CAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTGCC
AAAAGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGA
AGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATA
ATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTAT
AATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGAT
GATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAG
AAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGA
TCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGAT
ATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTT
GTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAG
CTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTG
GATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTT
CAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAG
TTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAAT
GATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAG
AGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTT
GGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAA
AAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGT
GACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAAC
TTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATC
AGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAG
AAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAAT
GGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGC
CTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAA
GAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTC
GGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGC
TACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTAC
TTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAA
GGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCC
AGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAA
ATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGC
CGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGCATTTGAGACGGAGTTGGCTTATCTCTCAGGA
AATAGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGTT
GGCGATGCTGCAGGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTACTT
CTACACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTGCCACAGGTATTCCTCACAGAGTCCTTACTG
AGACCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAACAGG
ATAACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTAACAACCAAGAAGACTGGAGGCCAAACAGTC
ATCCAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATTGTC
TTTACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTTGAGGACCATCAGGCAGCCATCAACAACTTC
TGGGTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTCAGG
AGCTGCTGTCACCTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGTGTGATGTGTGATAATGCAAGCATAGTACTT

>In-frame_PBRM1_ENST00000409057_chr3_52595783_-_FBXW12_ENST00000445170_chr3_48416844_+_5397nt
ATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAGGC
CCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACTAT
AAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCTCAG
CCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTTTTT
AACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAATGAG
TTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCAGCT
TACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAGAAA
CTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAATGGA
AGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTATTC
AAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATGAGG
ACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAGTAT
TACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCTGCT
TTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTTTAT
GACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGATTAT
TACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGTGT
GATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTATG
CAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTGCC
AAAAGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGA
AGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATA
ATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTAT
AATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGAT
GATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAG
AAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGA
TCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGAT
ATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTT
GTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAG
CTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTG
GATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTT
CAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAG
TTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAAT
GATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAG
AGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTT
GGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAA
AAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGT
GACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAAC
TTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATC
AGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAG
AAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAAT
GGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGC
CTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAA
GAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTC
GGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGC
TACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTAC
TTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAA
GGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCC
AGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAA
ATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGC
CGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGCATTTGAGACGGAGTTGGCTTATCTCTCAGGA
AATAGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGGT
ACCATGATCTGGTCAAGCCCAGTCCAGGAGTTCCATTTCTCAAATCTGGTAACCCTCCCTCAGATGCATCTCGCCATCACTATGGATCGG
AAAAAAACTATCAAAGTGTGGAACTGTCAGGACAGGGACGCTCTGGCTGTTCTCCCCATGCCACAGCCCTGTTATTGCATGGAAGCCTAT
CTTACAAAGGATGGCCCATTCCTGATGGTTGGCGATGCTGCAGGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAA
GTTACTGCATTTCAATATGGTATTGTACTTCTACACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTG
CCACAGGTATTCCTCACAGAGTCCTTACTGAGACCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGC
GCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTA
ACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGG
ATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTT
GAGGACCATCAGGCAGCCATCAACAACTTCTGGGTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGG
GAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCACCTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGT

>In-frame_PBRM1_ENST00000409114_chr3_52595783_-_FBXW12_ENST00000296438_chr3_48416844_+_5442nt
ATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAGGC
CCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACTAT
AAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCTCAG
CCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTTTTT
AACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAATGAG
TTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCAGCT
TACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAGAAA
CTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAATGGA
AGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTATTC
AAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATGAGG
ACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAGTAT
TACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCTGCT
TTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTTTAT
GACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGATTAT
TACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGTGT
GATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTATG
CAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTGCC
AAAAGAAAAAGGAACACTCATGACAGTGAGATGTTGGGTCTCAGGAGGCTATCCAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATC
TTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTAT
CCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGA
ATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAG
AAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGT
GGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAG
AGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGAC
ATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCC
TGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGA
GATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGAT
GAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATT
AGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAAT
CGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATT
CTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAG
GAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGC
ACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCA
CATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAAAAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTC
CACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGT
GTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCC
AAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTT
CGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTT
AACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGAC
ATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGA
GATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTA
TTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGG
CCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAG
AGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTG
GAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAG
GTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCA
AAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCT
GTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAA
GCAGAATATGAAGCATTTGAGACGGAGTTGGCTTATCTCTCAGGAAATAGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGTAGT
GTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGGTACCATGATCTGGTCAAGCCCAGTCCAGGAGTTCCATTTCTCAAAT
CTGGTAACCCTCCCTCAGATGCATCTCGCCATCACTATGGATCGGAAAAAAACTATCAAAGTGTGGAACTGTCAGGACAGGGACGCTCTG
GCTGTTCTCCCCATGCCACAGCCCTGTTATTGCATGGAAGCCTATCTTACAAAGGATGGCCCATTCCTGATGGTTGGCGATGCTGCAGGT
GACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTACTTCTACACTGCTCTCCT
GACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTGCCACAGGTATTCCTCACAGAGTCCTTACTGAGACCATCAGAAGGC
AGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTGATGTCC
CAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTAACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCATATGAG
ATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGTGGACCA
TACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTTGAGGACCATCAGGCAGCCATCAACAACTTCTGGGTGGATCCTTGC
TATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCACCTG
GAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGTGTGATGTGTGATAATGCAAGCATAGTACTTAGGGTGAGGAAAGTA

>In-frame_PBRM1_ENST00000409114_chr3_52595783_-_FBXW12_ENST00000415155_chr3_48416844_+_5232nt
ATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAGGC
CCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACTAT
AAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCTCAG
CCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTTTTT
AACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAATGAG
TTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCAGCT
TACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAGAAA
CTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAATGGA
AGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTATTC
AAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATGAGG
ACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAGTAT
TACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCTGCT
TTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTTTAT
GACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGATTAT
TACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGTGT
GATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTATG
CAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTGCC
AAAAGAAAAAGGAACACTCATGACAGTGAGATGTTGGGTCTCAGGAGGCTATCCAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATC
TTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTAT
CCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGA
ATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAG
AAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGT
GGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAG
AGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGAC
ATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCC
TGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGA
GATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGAT
GAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATT
AGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAAT
CGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATT
CTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAG
GAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGC
ACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCA
CATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAAAAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTC
CACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGT
GTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCC
AAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTT
CGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTT
AACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGAC
ATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGA
GATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTA
TTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGG
CCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAG
AGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTG
GAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAG
GTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCA
AAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCT
GTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAA
GCAGAATATGAAGCATTTGAGACGGAGTTGGCTTATCTCTCAGGAAATAGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGTAGT
GTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGTTGGCGATGCTGCAGGTGACATCTACACATTTACACTGCCTGGGTTA
AGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTACTTCTACACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGGACA
TACAGTCGTACCTTGCCACAGGTATTCCTCACAGAGTCCTTACTGAGACCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACAT
AAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTT
ATCACCTTTGATCTAACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTG
AAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGCTTC
CTGCTGCAACGATTTGAGGACCATCAGGCAGCCATCAACAACTTCTGGGTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCTGTG
CACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCACCTGGAAAACACGTGGCATGATCACACAACAGAC
AGCTGCATCTCCAGTGTGATGTGTGATAATGCAAGCATAGTACTTAGGGTGAGGAAAGTAAGTGACTCCAGCATTCTGGTGATGTATTCT

>In-frame_PBRM1_ENST00000409114_chr3_52595783_-_FBXW12_ENST00000445170_chr3_48416844_+_5442nt
ATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAGGC
CCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACTAT
AAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCTCAG
CCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTTTTT
AACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAATGAG
TTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCAGCT
TACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAGAAA
CTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAATGGA
AGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTATTC
AAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATGAGG
ACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAGTAT
TACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCTGCT
TTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTTTAT
GACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGATTAT
TACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGTGT
GATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTATG
CAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTGCC
AAAAGAAAAAGGAACACTCATGACAGTGAGATGTTGGGTCTCAGGAGGCTATCCAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATC
TTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTAT
CCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGA
ATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAG
AAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGT
GGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAG
AGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGAC
ATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCC
TGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGA
GATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGAT
GAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATT
AGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAAT
CGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATT
CTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAG
GAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGC
ACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCA
CATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAAAAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTC
CACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGT
GTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCC
AAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTT
CGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTT
AACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGAC
ATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGA
GATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTA
TTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGG
CCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAG
AGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTG
GAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAG
GTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCA
AAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCT
GTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAA
GCAGAATATGAAGCATTTGAGACGGAGTTGGCTTATCTCTCAGGAAATAGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGTAGT
GTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGGTACCATGATCTGGTCAAGCCCAGTCCAGGAGTTCCATTTCTCAAAT
CTGGTAACCCTCCCTCAGATGCATCTCGCCATCACTATGGATCGGAAAAAAACTATCAAAGTGTGGAACTGTCAGGACAGGGACGCTCTG
GCTGTTCTCCCCATGCCACAGCCCTGTTATTGCATGGAAGCCTATCTTACAAAGGATGGCCCATTCCTGATGGTTGGCGATGCTGCAGGT
GACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTACTTCTACACTGCTCTCCT
GACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTGCCACAGGTATTCCTCACAGAGTCCTTACTGAGACCATCAGAAGGC
AGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTGATGTCC
CAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTAACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCATATGAG
ATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGTGGACCA
TACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTTGAGGACCATCAGGCAGCCATCAACAACTTCTGGGTGGATCCTTGC
TATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCACCTG
GAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGTGTGATGTGTGATAATGCAAGCATAGTACTTAGGGTGAGGAAAGTA

>In-frame_PBRM1_ENST00000409767_chr3_52595783_-_FBXW12_ENST00000296438_chr3_48416844_+_5442nt
ATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAGGC
CCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACTAT
AAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCTCAG
CCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTTTTT
AACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAATGAG
TTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCAGCT
TACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAGAAA
CTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAATGGA
AGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTATTC
AAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATGAGG
ACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAGTAT
TACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCTGCT
TTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTTTAT
GACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGATTAT
TACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGTGT
GATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTATG
CAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTGCC
AAAAGAAAAAGGAACACTCATGACAGTGAGATGTTGGGTCTCAGGAGGCTATCCAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATC
TTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTAT
CCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGA
ATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAG
AAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGT
GGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAG
AGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGAC
ATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCC
TGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGA
GATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGAT
GAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATT
AGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAAT
CGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATT
CTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAG
GAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGC
ACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCA
CATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAAAAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTC
CACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGT
GTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCC
AAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTT
CGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTT
AACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGAC
ATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGA
GATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTA
TTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGG
CCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAG
AGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTG
GAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAG
GTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCA
AAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCT
GTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAA
GCAGAATATGAAGCATTTGAGACGGAGTTGGCTTATCTCTCAGGAAATAGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGTAGT
GTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGGTACCATGATCTGGTCAAGCCCAGTCCAGGAGTTCCATTTCTCAAAT
CTGGTAACCCTCCCTCAGATGCATCTCGCCATCACTATGGATCGGAAAAAAACTATCAAAGTGTGGAACTGTCAGGACAGGGACGCTCTG
GCTGTTCTCCCCATGCCACAGCCCTGTTATTGCATGGAAGCCTATCTTACAAAGGATGGCCCATTCCTGATGGTTGGCGATGCTGCAGGT
GACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTACTTCTACACTGCTCTCCT
GACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTGCCACAGGTATTCCTCACAGAGTCCTTACTGAGACCATCAGAAGGC
AGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTGATGTCC
CAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTAACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCATATGAG
ATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGTGGACCA
TACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTTGAGGACCATCAGGCAGCCATCAACAACTTCTGGGTGGATCCTTGC
TATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCACCTG
GAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGTGTGATGTGTGATAATGCAAGCATAGTACTTAGGGTGAGGAAAGTA

>In-frame_PBRM1_ENST00000409767_chr3_52595783_-_FBXW12_ENST00000415155_chr3_48416844_+_5232nt
ATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAGGC
CCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACTAT
AAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCTCAG
CCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTTTTT
AACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAATGAG
TTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCAGCT
TACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAGAAA
CTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAATGGA
AGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTATTC
AAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATGAGG
ACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAGTAT
TACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCTGCT
TTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTTTAT
GACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGATTAT
TACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGTGT
GATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTATG
CAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTGCC
AAAAGAAAAAGGAACACTCATGACAGTGAGATGTTGGGTCTCAGGAGGCTATCCAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATC
TTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTAT
CCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGA
ATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAG
AAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGT
GGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAG
AGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGAC
ATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCC
TGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGA
GATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGAT
GAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATT
AGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAAT
CGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATT
CTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAG
GAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGC
ACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCA
CATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAAAAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTC
CACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGT
GTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCC
AAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTT
CGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTT
AACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGAC
ATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGA
GATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTA
TTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGG
CCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAG
AGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTG
GAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAG
GTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCA
AAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCT
GTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAA
GCAGAATATGAAGCATTTGAGACGGAGTTGGCTTATCTCTCAGGAAATAGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGTAGT
GTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGTTGGCGATGCTGCAGGTGACATCTACACATTTACACTGCCTGGGTTA
AGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTACTTCTACACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGGACA
TACAGTCGTACCTTGCCACAGGTATTCCTCACAGAGTCCTTACTGAGACCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACAT
AAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTT
ATCACCTTTGATCTAACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTG
AAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGCTTC
CTGCTGCAACGATTTGAGGACCATCAGGCAGCCATCAACAACTTCTGGGTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCTGTG
CACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCACCTGGAAAACACGTGGCATGATCACACAACAGAC
AGCTGCATCTCCAGTGTGATGTGTGATAATGCAAGCATAGTACTTAGGGTGAGGAAAGTAAGTGACTCCAGCATTCTGGTGATGTATTCT

>In-frame_PBRM1_ENST00000409767_chr3_52595783_-_FBXW12_ENST00000445170_chr3_48416844_+_5442nt
ATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAGGC
CCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACTAT
AAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCTCAG
CCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTTTTT
AACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAATGAG
TTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCAGCT
TACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAGAAA
CTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAATGGA
AGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTATTC
AAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATGAGG
ACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAGTAT
TACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCTGCT
TTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTTTAT
GACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGATTAT
TACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGTGT
GATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTATG
CAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTGCC
AAAAGAAAAAGGAACACTCATGACAGTGAGATGTTGGGTCTCAGGAGGCTATCCAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATC
TTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTAT
CCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGA
ATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAG
AAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGT
GGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAG
AGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGAC
ATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCC
TGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGA
GATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGAT
GAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATT
AGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAAT
CGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATT
CTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAG
GAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGC
ACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCA
CATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAAAAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTC
CACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGT
GTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCC
AAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTT
CGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTT
AACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGAC
ATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGA
GATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTA
TTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGG
CCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAG
AGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTG
GAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAG
GTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCA
AAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCT
GTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAA
GCAGAATATGAAGCATTTGAGACGGAGTTGGCTTATCTCTCAGGAAATAGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGTAGT
GTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGGTACCATGATCTGGTCAAGCCCAGTCCAGGAGTTCCATTTCTCAAAT
CTGGTAACCCTCCCTCAGATGCATCTCGCCATCACTATGGATCGGAAAAAAACTATCAAAGTGTGGAACTGTCAGGACAGGGACGCTCTG
GCTGTTCTCCCCATGCCACAGCCCTGTTATTGCATGGAAGCCTATCTTACAAAGGATGGCCCATTCCTGATGGTTGGCGATGCTGCAGGT
GACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTACTTCTACACTGCTCTCCT
GACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTGCCACAGGTATTCCTCACAGAGTCCTTACTGAGACCATCAGAAGGC
AGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTGATGTCC
CAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTAACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCATATGAG
ATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGTGGACCA
TACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTTGAGGACCATCAGGCAGCCATCAACAACTTCTGGGTGGATCCTTGC
TATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCACCTG
GAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGTGTGATGTGTGATAATGCAAGCATAGTACTTAGGGTGAGGAAAGTA

>In-frame_PBRM1_ENST00000296302_chr3_52592265_-_FBXW12_ENST00000296438_chr3_48416844_+_5562nt
ATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAGGC
CCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACTAT
AAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCTCAG
CCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTTTTT
AACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAATGAG
TTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCAGCT
TACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAGAAA
CTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAATGGA
AGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTATTC
AAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATGAGG
ACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAGTAT
TACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCTGCT
TTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTTTAT
GACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGATTAT
TACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGTGT
GATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTATG
CAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTGCC
AAAAGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGA
AGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATA
ATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTAT
AATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGAT
GATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAG
AAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGA
TCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGAT
ATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTT
GTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAG
CTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTG
GATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTT
CAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAG
TTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAAT
GATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAG
AGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTT
GGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAA
AAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGT
GACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAAC
TTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATC
AGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAG
AAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAAT
GGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGC
CTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAA
GAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTC
GGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGC
TACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTAC
TTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAA
GGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCC
AGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAA
ATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGC
CGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGAGCGGGCAGCTAAAGTTGCTGAGCAGCAGGAG
AGAGAGCGAGCAGCACAGCAACAGCAGCCGAGTGCTTCTCCCCGAGCAGGCACCCCTGTGGGGGCTCTCATGGGGGTGGTGCCACCACCA
ACACCAATGGGGATGCTCAATCAGCAGTTGACACCTGTTGCAGCATTTGAGACGGAGTTGGCTTATCTCTCAGGAAATAGACTTACAGTG
GATGAACAGGAGAAATCAATCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGGTACCATGATCTGGTCA
AGCCCAGTCCAGGAGTTCCATTTCTCAAATCTGGTAACCCTCCCTCAGATGCATCTCGCCATCACTATGGATCGGAAAAAAACTATCAAA
GTGTGGAACTGTCAGGACAGGGACGCTCTGGCTGTTCTCCCCATGCCACAGCCCTGTTATTGCATGGAAGCCTATCTTACAAAGGATGGC
CCATTCCTGATGGTTGGCGATGCTGCAGGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAAGTTACTGCATTTCAA
TATGGTATTGTACTTCTACACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTGCCACAGGTATTCCTC
ACAGAGTCCTTACTGAGACCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGCGCCTGCTGGACCCCA
AAGGTGAAAAACAGGATAACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTAACAACCAAGAAGACT
GGAGGCCAAACAGTCATCCAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGGATGGGAGCCAGTGAT
GGATATATGATTGTCTTTACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTTGAGGACCATCAGGCA
GCCATCAACAACTTCTGGGTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGGGAAGAAGGAGGCCGC
CATCCATACCTCAGGAGCTGCTGTCACCTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGTGTGATGTGTGATAAT

>In-frame_PBRM1_ENST00000296302_chr3_52592265_-_FBXW12_ENST00000415155_chr3_48416844_+_5352nt
ATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAGGC
CCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACTAT
AAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCTCAG
CCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTTTTT
AACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAATGAG
TTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCAGCT
TACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAGAAA
CTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAATGGA
AGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTATTC
AAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATGAGG
ACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAGTAT
TACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCTGCT
TTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTTTAT
GACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGATTAT
TACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGTGT
GATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTATG
CAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTGCC
AAAAGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGA
AGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATA
ATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTAT
AATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGAT
GATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAG
AAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGA
TCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGAT
ATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTT
GTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAG
CTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTG
GATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTT
CAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAG
TTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAAT
GATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAG
AGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTT
GGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAA
AAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGT
GACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAAC
TTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATC
AGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAG
AAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAAT
GGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGC
CTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAA
GAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTC
GGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGC
TACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTAC
TTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAA
GGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCC
AGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAA
ATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGC
CGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGAGCGGGCAGCTAAAGTTGCTGAGCAGCAGGAG
AGAGAGCGAGCAGCACAGCAACAGCAGCCGAGTGCTTCTCCCCGAGCAGGCACCCCTGTGGGGGCTCTCATGGGGGTGGTGCCACCACCA
ACACCAATGGGGATGCTCAATCAGCAGTTGACACCTGTTGCAGCATTTGAGACGGAGTTGGCTTATCTCTCAGGAAATAGACTTACAGTG
GATGAACAGGAGAAATCAATCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGTTGGCGATGCTGCAGGT
GACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTACTTCTACACTGCTCTCCT
GACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTGCCACAGGTATTCCTCACAGAGTCCTTACTGAGACCATCAGAAGGC
AGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTGATGTCC
CAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTAACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCATATGAG
ATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGTGGACCA
TACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTTGAGGACCATCAGGCAGCCATCAACAACTTCTGGGTGGATCCTTGC
TATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCACCTG
GAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGTGTGATGTGTGATAATGCAAGCATAGTACTTAGGGTGAGGAAAGTA

>In-frame_PBRM1_ENST00000296302_chr3_52592265_-_FBXW12_ENST00000445170_chr3_48416844_+_5562nt
ATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAGGC
CCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACTAT
AAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCTCAG
CCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTTTTT
AACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAATGAG
TTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCAGCT
TACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAGAAA
CTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAATGGA
AGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTATTC
AAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATGAGG
ACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAGTAT
TACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCTGCT
TTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTTTAT
GACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGATTAT
TACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGTGT
GATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTATG
CAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTGCC
AAAAGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGA
AGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATA
ATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTAT
AATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGAT
GATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAG
AAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGA
TCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGAT
ATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTT
GTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAG
CTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTG
GATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTT
CAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAG
TTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAAT
GATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAG
AGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTT
GGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAA
AAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGT
GACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAAC
TTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATC
AGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAG
AAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAAT
GGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGC
CTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAA
GAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTC
GGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGC
TACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTAC
TTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAA
GGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCC
AGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAA
ATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGC
CGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGAGCGGGCAGCTAAAGTTGCTGAGCAGCAGGAG
AGAGAGCGAGCAGCACAGCAACAGCAGCCGAGTGCTTCTCCCCGAGCAGGCACCCCTGTGGGGGCTCTCATGGGGGTGGTGCCACCACCA
ACACCAATGGGGATGCTCAATCAGCAGTTGACACCTGTTGCAGCATTTGAGACGGAGTTGGCTTATCTCTCAGGAAATAGACTTACAGTG
GATGAACAGGAGAAATCAATCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGGTACCATGATCTGGTCA
AGCCCAGTCCAGGAGTTCCATTTCTCAAATCTGGTAACCCTCCCTCAGATGCATCTCGCCATCACTATGGATCGGAAAAAAACTATCAAA
GTGTGGAACTGTCAGGACAGGGACGCTCTGGCTGTTCTCCCCATGCCACAGCCCTGTTATTGCATGGAAGCCTATCTTACAAAGGATGGC
CCATTCCTGATGGTTGGCGATGCTGCAGGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAAGTTACTGCATTTCAA
TATGGTATTGTACTTCTACACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTGCCACAGGTATTCCTC
ACAGAGTCCTTACTGAGACCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGCGCCTGCTGGACCCCA
AAGGTGAAAAACAGGATAACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTAACAACCAAGAAGACT
GGAGGCCAAACAGTCATCCAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGGATGGGAGCCAGTGAT
GGATATATGATTGTCTTTACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTTGAGGACCATCAGGCA
GCCATCAACAACTTCTGGGTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGGGAAGAAGGAGGCCGC
CATCCATACCTCAGGAGCTGCTGTCACCTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGTGTGATGTGTGATAAT

>In-frame_PBRM1_ENST00000409114_chr3_52592265_-_FBXW12_ENST00000296438_chr3_48416844_+_5607nt
ATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAGGC
CCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACTAT
AAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCTCAG
CCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTTTTT
AACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAATGAG
TTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCAGCT
TACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAGAAA
CTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAATGGA
AGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTATTC
AAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATGAGG
ACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAGTAT
TACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCTGCT
TTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTTTAT
GACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGATTAT
TACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGTGT
GATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTATG
CAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTGCC
AAAAGAAAAAGGAACACTCATGACAGTGAGATGTTGGGTCTCAGGAGGCTATCCAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATC
TTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTAT
CCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGA
ATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAG
AAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGT
GGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAG
AGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGAC
ATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCC
TGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGA
GATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGAT
GAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATT
AGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAAT
CGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATT
CTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAG
GAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGC
ACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCA
CATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAAAAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTC
CACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGT
GTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCC
AAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTT
CGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTT
AACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGAC
ATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGA
GATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTA
TTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGG
CCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAG
AGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTG
GAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAG
GTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCA
AAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCT
GTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAA
GCAGAATATGAAGAGCGGGCAGCTAAAGTTGCTGAGCAGCAGGAGAGAGAGCGAGCAGCACAGCAACAGCAGCCGAGTGCTTCTCCCCGA
GCAGGCACCCCTGTGGGGGCTCTCATGGGGGTGGTGCCACCACCAACACCAATGGGGATGCTCAATCAGCAGTTGACACCTGTTGCAGCA
TTTGAGACGGAGTTGGCTTATCTCTCAGGAAATAGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGTAGTGTATCTCCAAAGCAA
GAGCTTTGTGCCTGGGATGTGCAAGAGGGTACCATGATCTGGTCAAGCCCAGTCCAGGAGTTCCATTTCTCAAATCTGGTAACCCTCCCT
CAGATGCATCTCGCCATCACTATGGATCGGAAAAAAACTATCAAAGTGTGGAACTGTCAGGACAGGGACGCTCTGGCTGTTCTCCCCATG
CCACAGCCCTGTTATTGCATGGAAGCCTATCTTACAAAGGATGGCCCATTCCTGATGGTTGGCGATGCTGCAGGTGACATCTACACATTT
ACACTGCCTGGGTTAAGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTACTTCTACACTGCTCTCCTGACAAGAAATGGGTA
TTTGCATGTGGGACATACAGTCGTACCTTGCCACAGGTATTCCTCACAGAGTCCTTACTGAGACCATCAGAAGGCAGTGTTCCTCTGTCT
ACCTTTCTCCCACATAAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTGATGTCCCAAAGTAGCACTGGA
AAAAAGACAGAATTTATCACCTTTGATCTAACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCATATGAGATCGCAAGTTTCCAG
GTGGCAGCTCATCTGAAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGTGGACCATACTTGTTACTCTTC
AGCATCACTGGCTTCCTGCTGCAACGATTTGAGGACCATCAGGCAGCCATCAACAACTTCTGGGTGGATCCTTGCTATGTGCTCACCACA
TCCGAGAACTCTGTGCACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCACCTGGAAAACACGTGGCAT
GATCACACAACAGACAGCTGCATCTCCAGTGTGATGTGTGATAATGCAAGCATAGTACTTAGGGTGAGGAAAGTAAGTGACTCCAGCATT

>In-frame_PBRM1_ENST00000409114_chr3_52592265_-_FBXW12_ENST00000415155_chr3_48416844_+_5397nt
ATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAGGC
CCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACTAT
AAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCTCAG
CCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTTTTT
AACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAATGAG
TTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCAGCT
TACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAGAAA
CTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAATGGA
AGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTATTC
AAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATGAGG
ACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAGTAT
TACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCTGCT
TTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTTTAT
GACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGATTAT
TACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGTGT
GATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTATG
CAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTGCC
AAAAGAAAAAGGAACACTCATGACAGTGAGATGTTGGGTCTCAGGAGGCTATCCAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATC
TTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTAT
CCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGA
ATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAG
AAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGT
GGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAG
AGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGAC
ATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCC
TGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGA
GATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGAT
GAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATT
AGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAAT
CGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATT
CTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAG
GAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGC
ACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCA
CATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAAAAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTC
CACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGT
GTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCC
AAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTT
CGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTT
AACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGAC
ATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGA
GATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTA
TTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGG
CCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAG
AGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTG
GAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAG
GTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCA
AAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCT
GTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAA
GCAGAATATGAAGAGCGGGCAGCTAAAGTTGCTGAGCAGCAGGAGAGAGAGCGAGCAGCACAGCAACAGCAGCCGAGTGCTTCTCCCCGA
GCAGGCACCCCTGTGGGGGCTCTCATGGGGGTGGTGCCACCACCAACACCAATGGGGATGCTCAATCAGCAGTTGACACCTGTTGCAGCA
TTTGAGACGGAGTTGGCTTATCTCTCAGGAAATAGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGTAGTGTATCTCCAAAGCAA
GAGCTTTGTGCCTGGGATGTGCAAGAGGTTGGCGATGCTGCAGGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAA
GTTACTGCATTTCAATATGGTATTGTACTTCTACACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTG
CCACAGGTATTCCTCACAGAGTCCTTACTGAGACCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGC
GCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTA
ACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGG
ATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTT
GAGGACCATCAGGCAGCCATCAACAACTTCTGGGTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGG
GAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCACCTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGT

>In-frame_PBRM1_ENST00000409114_chr3_52592265_-_FBXW12_ENST00000445170_chr3_48416844_+_5607nt
ATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAGGC
CCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACTAT
AAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCTCAG
CCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTTTTT
AACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAATGAG
TTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCAGCT
TACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAGAAA
CTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAATGGA
AGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTATTC
AAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATGAGG
ACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAGTAT
TACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCTGCT
TTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTTTAT
GACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGATTAT
TACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGTGT
GATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTATG
CAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTGCC
AAAAGAAAAAGGAACACTCATGACAGTGAGATGTTGGGTCTCAGGAGGCTATCCAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATC
TTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTAT
CCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGA
ATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAG
AAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGT
GGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAG
AGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGAC
ATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCC
TGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGA
GATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGAT
GAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATT
AGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAAT
CGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATT
CTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAG
GAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGC
ACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCA
CATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAAAAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTC
CACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGT
GTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCC
AAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTT
CGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTT
AACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGAC
ATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGA
GATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTA
TTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGG
CCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAG
AGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTG
GAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAG
GTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCA
AAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCT
GTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAA
GCAGAATATGAAGAGCGGGCAGCTAAAGTTGCTGAGCAGCAGGAGAGAGAGCGAGCAGCACAGCAACAGCAGCCGAGTGCTTCTCCCCGA
GCAGGCACCCCTGTGGGGGCTCTCATGGGGGTGGTGCCACCACCAACACCAATGGGGATGCTCAATCAGCAGTTGACACCTGTTGCAGCA
TTTGAGACGGAGTTGGCTTATCTCTCAGGAAATAGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGTAGTGTATCTCCAAAGCAA
GAGCTTTGTGCCTGGGATGTGCAAGAGGGTACCATGATCTGGTCAAGCCCAGTCCAGGAGTTCCATTTCTCAAATCTGGTAACCCTCCCT
CAGATGCATCTCGCCATCACTATGGATCGGAAAAAAACTATCAAAGTGTGGAACTGTCAGGACAGGGACGCTCTGGCTGTTCTCCCCATG
CCACAGCCCTGTTATTGCATGGAAGCCTATCTTACAAAGGATGGCCCATTCCTGATGGTTGGCGATGCTGCAGGTGACATCTACACATTT
ACACTGCCTGGGTTAAGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTACTTCTACACTGCTCTCCTGACAAGAAATGGGTA
TTTGCATGTGGGACATACAGTCGTACCTTGCCACAGGTATTCCTCACAGAGTCCTTACTGAGACCATCAGAAGGCAGTGTTCCTCTGTCT
ACCTTTCTCCCACATAAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTGATGTCCCAAAGTAGCACTGGA
AAAAAGACAGAATTTATCACCTTTGATCTAACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCATATGAGATCGCAAGTTTCCAG
GTGGCAGCTCATCTGAAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGTGGACCATACTTGTTACTCTTC
AGCATCACTGGCTTCCTGCTGCAACGATTTGAGGACCATCAGGCAGCCATCAACAACTTCTGGGTGGATCCTTGCTATGTGCTCACCACA
TCCGAGAACTCTGTGCACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCACCTGGAAAACACGTGGCAT
GATCACACAACAGACAGCTGCATCTCCAGTGTGATGTGTGATAATGCAAGCATAGTACTTAGGGTGAGGAAAGTAAGTGACTCCAGCATT


* Fusion transcript sequences (Full-length transcript).
>In-frame_PBRM1_ENST00000356770_chr3_52595783_-_FBXW12_ENST00000296438_chr3_48416844_+_5370nt
TCCATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCA
GGCCCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGAC
TATAAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCT
CAGCCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTT
TTTAACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAAT
GAGTTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCA
GCTTACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAG
AAACTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAAT
GGAAGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTA
TTCAAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATG
AGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCTGCTTTA
GCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTTTATGAC
ACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGATTATTAC
CAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGTGTGAT
CTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTATGCAG
GCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTGCCAAA
AGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGAAGA
CTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATAATT
GAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTATAAT
GAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGATGAT
GATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAGAAA
CTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGATCT
GAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGATATT
GACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTTGTT
CTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAGCTT
ATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTGGAT
CCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTTCAA
GAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAGTTT
TTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAATGAT
GTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAGAGT
GAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTTGGA
GATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAAAAA
TGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGTGAC
TATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAACTTC
CGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATCAGC
TCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAGAAG
AATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAATGGT
GAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGCCTG
GTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAAGAA
ACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTCGGA
AAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGCTAC
AATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTACTTC
AGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAAGGT
GGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCCAGT
GAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAAATC
AACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGCCGC
CTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGCATTTGAGACGGAGTTGGCTTATCTCTCAGGAAAT
AGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGGTACC
ATGATCTGGTCAAGCCCAGTCCAGGAGTTCCATTTCTCAAATCTGGTAACCCTCCCTCAGATGCATCTCGCCATCACTATGGATCGGAAA
AAAACTATCAAAGTGTGGAACTGTCAGGACAGGGACGCTCTGGCTGTTCTCCCCATGCCACAGCCCTGTTATTGCATGGAAGCCTATCTT
ACAAAGGATGGCCCATTCCTGATGGTTGGCGATGCTGCAGGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAAGTT
ACTGCATTTCAATATGGTATTGTACTTCTACACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTGCCA
CAGGTATTCCTCACAGAGTCCTTACTGAGACCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGCGCC
TGCTGGACCCCAAAGGTGAAAAACAGGATAACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTAACA
ACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGGATG
GGAGCCAGTGATGGATATATGATTGTCTTTACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTTGAG
GACCATCAGGCAGCCATCAACAACTTCTGGGTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGGGAA
GAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCACCTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGTGTG
ATGTGTGATAATGCAAGCATAGTACTTAGGGTGAGGAAAGTAAGTGACTCCAGCATTCTGGTGATGTATTCTTTGAATACGTAATATGGA

>In-frame_PBRM1_ENST00000356770_chr3_52595783_-_FBXW12_ENST00000415155_chr3_48416844_+_5122nt
TCCATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCA
GGCCCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGAC
TATAAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCT
CAGCCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTT
TTTAACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAAT
GAGTTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCA
GCTTACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAG
AAACTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAAT
GGAAGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTA
TTCAAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATG
AGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCTGCTTTA
GCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTTTATGAC
ACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGATTATTAC
CAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGTGTGAT
CTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTATGCAG
GCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTGCCAAA
AGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGAAGA
CTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATAATT
GAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTATAAT
GAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGATGAT
GATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAGAAA
CTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGATCT
GAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGATATT
GACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTTGTT
CTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAGCTT
ATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTGGAT
CCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTTCAA
GAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAGTTT
TTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAATGAT
GTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAGAGT
GAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTTGGA
GATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAAAAA
TGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGTGAC
TATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAACTTC
CGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATCAGC
TCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAGAAG
AATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAATGGT
GAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGCCTG
GTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAAGAA
ACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTCGGA
AAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGCTAC
AATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTACTTC
AGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAAGGT
GGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCCAGT
GAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAAATC
AACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGCCGC
CTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGCATTTGAGACGGAGTTGGCTTATCTCTCAGGAAAT
AGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGTTGGC
GATGCTGCAGGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTACTTCTA
CACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTGCCACAGGTATTCCTCACAGAGTCCTTACTGAGA
CCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATA
ACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTAACAACCAAGAAGACTGGAGGCCAAACAGTCATC
CAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATTGTCTTT
ACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTTGAGGACCATCAGGCAGCCATCAACAACTTCTGG
GTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGC
TGCTGTCACCTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGTGTGATGTGTGATAATGCAAGCATAGTACTTAGG

>In-frame_PBRM1_ENST00000356770_chr3_52595783_-_FBXW12_ENST00000445170_chr3_48416844_+_5332nt
TCCATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCA
GGCCCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGAC
TATAAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCT
CAGCCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTT
TTTAACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAAT
GAGTTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCA
GCTTACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAG
AAACTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAAT
GGAAGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTA
TTCAAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATG
AGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCTGCTTTA
GCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTTTATGAC
ACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGATTATTAC
CAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGTGTGAT
CTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTATGCAG
GCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTGCCAAA
AGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGAAGA
CTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATAATT
GAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTATAAT
GAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGATGAT
GATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAGAAA
CTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGATCT
GAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGATATT
GACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTTGTT
CTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAGCTT
ATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTGGAT
CCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTTCAA
GAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAGTTT
TTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAATGAT
GTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAGAGT
GAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTTGGA
GATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAAAAA
TGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGTGAC
TATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAACTTC
CGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATCAGC
TCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAGAAG
AATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAATGGT
GAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGCCTG
GTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAAGAA
ACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTCGGA
AAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGCTAC
AATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTACTTC
AGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAAGGT
GGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCCAGT
GAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAAATC
AACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGCCGC
CTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGCATTTGAGACGGAGTTGGCTTATCTCTCAGGAAAT
AGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGGTACC
ATGATCTGGTCAAGCCCAGTCCAGGAGTTCCATTTCTCAAATCTGGTAACCCTCCCTCAGATGCATCTCGCCATCACTATGGATCGGAAA
AAAACTATCAAAGTGTGGAACTGTCAGGACAGGGACGCTCTGGCTGTTCTCCCCATGCCACAGCCCTGTTATTGCATGGAAGCCTATCTT
ACAAAGGATGGCCCATTCCTGATGGTTGGCGATGCTGCAGGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAAGTT
ACTGCATTTCAATATGGTATTGTACTTCTACACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTGCCA
CAGGTATTCCTCACAGAGTCCTTACTGAGACCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGCGCC
TGCTGGACCCCAAAGGTGAAAAACAGGATAACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTAACA
ACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGGATG
GGAGCCAGTGATGGATATATGATTGTCTTTACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTTGAG
GACCATCAGGCAGCCATCAACAACTTCTGGGTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGGGAA
GAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCACCTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGTGTG
ATGTGTGATAATGCAAGCATAGTACTTAGGGTGAGGAAAGTAAGTGACTCCAGCATTCTGGTGATGTATTCTTTGAATACGTAATATGGA

>In-frame_PBRM1_ENST00000296302_chr3_52595783_-_FBXW12_ENST00000296438_chr3_48416844_+_5465nt
CCATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAG
GCCCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACT
ATAAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCTC
AGCCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTTT
TTAACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAATG
AGTTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCAG
CTTACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAGA
AACTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAATG
GAAGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTAT
TCAAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATGA
GGACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAGT
ATTACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCTG
CTTTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTTT
ATGACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGATT
ATTACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGT
GTGATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTA
TGCAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTG
CCAAAAGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCA
GAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAA
TAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACT
ATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTG
ATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGC
AGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTA
GATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAG
ATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTC
TTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAG
AGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTG
TGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTAT
TTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGC
AGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATA
ATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAA
AGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATG
TTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTG
AAAAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGA
GTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAA
ACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCA
TCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATG
AGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCA
ATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATG
GCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAG
AAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTC
TCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCC
GCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACT
ACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAG
AAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGG
CCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGA
AAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCA
GCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGCATTTGAGACGGAGTTGGCTTATCTCTCAG
GAAATAGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGG
GTACCATGATCTGGTCAAGCCCAGTCCAGGAGTTCCATTTCTCAAATCTGGTAACCCTCCCTCAGATGCATCTCGCCATCACTATGGATC
GGAAAAAAACTATCAAAGTGTGGAACTGTCAGGACAGGGACGCTCTGGCTGTTCTCCCCATGCCACAGCCCTGTTATTGCATGGAAGCCT
ATCTTACAAAGGATGGCCCATTCCTGATGGTTGGCGATGCTGCAGGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTA
AAGTTACTGCATTTCAATATGGTATTGTACTTCTACACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCT
TGCCACAGGTATTCCTCACAGAGTCCTTACTGAGACCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCA
GCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATC
TAACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCT
GGATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGAT
TTGAGGACCATCAGGCAGCCATCAACAACTTCTGGGTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGT
GGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCACCTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCA
GTGTGATGTGTGATAATGCAAGCATAGTACTTAGGGTGAGGAAAGTAAGTGACTCCAGCATTCTGGTGATGTATTCTTTGAATACGTAAT

>In-frame_PBRM1_ENST00000296302_chr3_52595783_-_FBXW12_ENST00000415155_chr3_48416844_+_5217nt
CCATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAG
GCCCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACT
ATAAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCTC
AGCCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTTT
TTAACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAATG
AGTTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCAG
CTTACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAGA
AACTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAATG
GAAGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTAT
TCAAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATGA
GGACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAGT
ATTACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCTG
CTTTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTTT
ATGACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGATT
ATTACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGT
GTGATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTA
TGCAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTG
CCAAAAGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCA
GAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAA
TAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACT
ATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTG
ATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGC
AGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTA
GATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAG
ATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTC
TTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAG
AGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTG
TGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTAT
TTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGC
AGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATA
ATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAA
AGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATG
TTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTG
AAAAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGA
GTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAA
ACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCA
TCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATG
AGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCA
ATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATG
GCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAG
AAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTC
TCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCC
GCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACT
ACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAG
AAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGG
CCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGA
AAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCA
GCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGCATTTGAGACGGAGTTGGCTTATCTCTCAG
GAAATAGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGG
TTGGCGATGCTGCAGGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTAC
TTCTACACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTGCCACAGGTATTCCTCACAGAGTCCTTAC
TGAGACCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAACA
GGATAACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTAACAACCAAGAAGACTGGAGGCCAAACAG
TCATCCAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATTG
TCTTTACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTTGAGGACCATCAGGCAGCCATCAACAACT
TCTGGGTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTCA
GGAGCTGCTGTCACCTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGTGTGATGTGTGATAATGCAAGCATAGTAC

>In-frame_PBRM1_ENST00000296302_chr3_52595783_-_FBXW12_ENST00000445170_chr3_48416844_+_5427nt
CCATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAG
GCCCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACT
ATAAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCTC
AGCCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTTT
TTAACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAATG
AGTTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCAG
CTTACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAGA
AACTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAATG
GAAGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTAT
TCAAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATGA
GGACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAGT
ATTACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCTG
CTTTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTTT
ATGACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGATT
ATTACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGT
GTGATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTA
TGCAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTG
CCAAAAGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCA
GAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAA
TAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACT
ATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTG
ATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGC
AGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTA
GATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAG
ATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTC
TTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAG
AGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTG
TGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTAT
TTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGC
AGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATA
ATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAA
AGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATG
TTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTG
AAAAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGA
GTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAA
ACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCA
TCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATG
AGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCA
ATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATG
GCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAG
AAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTC
TCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCC
GCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACT
ACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAG
AAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGG
CCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGA
AAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCA
GCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGCATTTGAGACGGAGTTGGCTTATCTCTCAG
GAAATAGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGG
GTACCATGATCTGGTCAAGCCCAGTCCAGGAGTTCCATTTCTCAAATCTGGTAACCCTCCCTCAGATGCATCTCGCCATCACTATGGATC
GGAAAAAAACTATCAAAGTGTGGAACTGTCAGGACAGGGACGCTCTGGCTGTTCTCCCCATGCCACAGCCCTGTTATTGCATGGAAGCCT
ATCTTACAAAGGATGGCCCATTCCTGATGGTTGGCGATGCTGCAGGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTA
AAGTTACTGCATTTCAATATGGTATTGTACTTCTACACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCT
TGCCACAGGTATTCCTCACAGAGTCCTTACTGAGACCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCA
GCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATC
TAACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCT
GGATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGAT
TTGAGGACCATCAGGCAGCCATCAACAACTTCTGGGTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGT
GGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCACCTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCA
GTGTGATGTGTGATAATGCAAGCATAGTACTTAGGGTGAGGAAAGTAAGTGACTCCAGCATTCTGGTGATGTATTCTTTGAATACGTAAT

>In-frame_PBRM1_ENST00000337303_chr3_52595783_-_FBXW12_ENST00000296438_chr3_48416844_+_5466nt
TCCATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCA
GGCCCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGAC
TATAAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCT
CAGCCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTT
TTTAACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAAT
GAGTTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCA
GCTTACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAG
AAACTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAAT
GGAAGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTA
TTCAAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATG
AGGACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAG
TATTACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCT
GCTTTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTT
TATGACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGAT
TATTACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAG
TGTGATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTT
ATGCAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGT
GCCAAAAGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGC
AGAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAA
ATAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCAC
TATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCT
GATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAG
CAGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCT
AGATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAA
GATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCT
CTTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAA
GAGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCT
GTGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTA
TTTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAG
CAGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCAT
AATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAA
AAGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCAT
GTTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGT
GAAAAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAG
AGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAA
AACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCC
ATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGAT
GAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCC
AATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCAT
GGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCA
GAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATT
CTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGC
CGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTAC
TACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTA
GAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTG
GCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGG
AAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTC
AGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGCATTTGAGACGGAGTTGGCTTATCTCTCA
GGAAATAGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAG
GGTACCATGATCTGGTCAAGCCCAGTCCAGGAGTTCCATTTCTCAAATCTGGTAACCCTCCCTCAGATGCATCTCGCCATCACTATGGAT
CGGAAAAAAACTATCAAAGTGTGGAACTGTCAGGACAGGGACGCTCTGGCTGTTCTCCCCATGCCACAGCCCTGTTATTGCATGGAAGCC
TATCTTACAAAGGATGGCCCATTCCTGATGGTTGGCGATGCTGCAGGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCT
AAAGTTACTGCATTTCAATATGGTATTGTACTTCTACACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACC
TTGCCACAGGTATTCCTCACAGAGTCCTTACTGAGACCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCC
AGCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGAT
CTAACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATC
TGGATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGA
TTTGAGGACCATCAGGCAGCCATCAACAACTTCTGGGTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATG
TGGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCACCTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCC
AGTGTGATGTGTGATAATGCAAGCATAGTACTTAGGGTGAGGAAAGTAAGTGACTCCAGCATTCTGGTGATGTATTCTTTGAATACGTAA

>In-frame_PBRM1_ENST00000337303_chr3_52595783_-_FBXW12_ENST00000415155_chr3_48416844_+_5218nt
TCCATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCA
GGCCCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGAC
TATAAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCT
CAGCCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTT
TTTAACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAAT
GAGTTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCA
GCTTACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAG
AAACTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAAT
GGAAGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTA
TTCAAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATG
AGGACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAG
TATTACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCT
GCTTTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTT
TATGACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGAT
TATTACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAG
TGTGATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTT
ATGCAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGT
GCCAAAAGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGC
AGAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAA
ATAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCAC
TATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCT
GATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAG
CAGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCT
AGATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAA
GATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCT
CTTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAA
GAGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCT
GTGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTA
TTTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAG
CAGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCAT
AATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAA
AAGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCAT
GTTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGT
GAAAAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAG
AGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAA
AACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCC
ATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGAT
GAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCC
AATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCAT
GGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCA
GAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATT
CTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGC
CGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTAC
TACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTA
GAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTG
GCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGG
AAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTC
AGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGCATTTGAGACGGAGTTGGCTTATCTCTCA
GGAAATAGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAG
GTTGGCGATGCTGCAGGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTA
CTTCTACACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTGCCACAGGTATTCCTCACAGAGTCCTTA
CTGAGACCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAAC
AGGATAACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTAACAACCAAGAAGACTGGAGGCCAAACA
GTCATCCAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATT
GTCTTTACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTTGAGGACCATCAGGCAGCCATCAACAAC
TTCTGGGTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTC
AGGAGCTGCTGTCACCTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGTGTGATGTGTGATAATGCAAGCATAGTA

>In-frame_PBRM1_ENST00000337303_chr3_52595783_-_FBXW12_ENST00000445170_chr3_48416844_+_5428nt
TCCATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCA
GGCCCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGAC
TATAAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCT
CAGCCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTT
TTTAACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAAT
GAGTTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCA
GCTTACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAG
AAACTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAAT
GGAAGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTA
TTCAAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATG
AGGACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAG
TATTACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCT
GCTTTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTT
TATGACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGAT
TATTACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAG
TGTGATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTT
ATGCAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGT
GCCAAAAGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGC
AGAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAA
ATAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCAC
TATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCT
GATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAG
CAGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCT
AGATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAA
GATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCT
CTTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAA
GAGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCT
GTGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTA
TTTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAG
CAGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCAT
AATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAA
AAGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCAT
GTTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGT
GAAAAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAG
AGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAA
AACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCC
ATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGAT
GAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCC
AATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCAT
GGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCA
GAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATT
CTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGC
CGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTAC
TACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTA
GAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTG
GCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGG
AAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTC
AGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGCATTTGAGACGGAGTTGGCTTATCTCTCA
GGAAATAGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAG
GGTACCATGATCTGGTCAAGCCCAGTCCAGGAGTTCCATTTCTCAAATCTGGTAACCCTCCCTCAGATGCATCTCGCCATCACTATGGAT
CGGAAAAAAACTATCAAAGTGTGGAACTGTCAGGACAGGGACGCTCTGGCTGTTCTCCCCATGCCACAGCCCTGTTATTGCATGGAAGCC
TATCTTACAAAGGATGGCCCATTCCTGATGGTTGGCGATGCTGCAGGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCT
AAAGTTACTGCATTTCAATATGGTATTGTACTTCTACACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACC
TTGCCACAGGTATTCCTCACAGAGTCCTTACTGAGACCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCC
AGCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGAT
CTAACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATC
TGGATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGA
TTTGAGGACCATCAGGCAGCCATCAACAACTTCTGGGTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATG
TGGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCACCTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCC
AGTGTGATGTGTGATAATGCAAGCATAGTACTTAGGGTGAGGAAAGTAAGTGACTCCAGCATTCTGGTGATGTATTCTTTGAATACGTAA

>In-frame_PBRM1_ENST00000410007_chr3_52595783_-_FBXW12_ENST00000296438_chr3_48416844_+_5391nt
TCCATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCA
GGCCCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGAC
TATAAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCT
CAGCCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTT
TTTAACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAAT
GAGTTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCA
GCTTACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAG
AAACTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAAT
GGAAGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTA
TTCAAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATG
AGGACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAG
TATTACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCT
GCTTTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTT
TATGACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGAT
TATTACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAG
TGTGATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTT
ATGCAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGT
GCCAAAAGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGC
AGAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAA
ATAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCAC
TATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCT
GATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAG
CAGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCT
AGATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAA
GATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCT
CTTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAA
GAGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCT
GTGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTA
TTTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAG
CAGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCAT
AATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAA
AAGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCAT
GTTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGAA
AAAGAAGTTTTTAAGAGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTT
AAGTTATGCCCAGAAAACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAA
CTGTGGACCATGCCCATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCA
GATAAAGGTGATGATGAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTC
CCTGTGGAAATGTCCAATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTC
TTCATCAAGTCCCATGGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCC
ATCTTCATTCACCCAGAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGC
CCCATGACATGTATTCTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATT
CTGCTTTGTGAGAGCCGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTA
GATGATGAAATTTACTACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCT
AAATTTGCCGAGTTAGAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAG
CTTCAGACCCCCCTGGCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAG
GAAGGCTCCAAACGGAAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTAC
TCTTTCGGGGAGCTCAGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGCATTTGAGACGGAG
TTGGCTTATCTCTCAGGAAATAGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCC
TGGGATGTGCAAGAGGGTACCATGATCTGGTCAAGCCCAGTCCAGGAGTTCCATTTCTCAAATCTGGTAACCCTCCCTCAGATGCATCTC
GCCATCACTATGGATCGGAAAAAAACTATCAAAGTGTGGAACTGTCAGGACAGGGACGCTCTGGCTGTTCTCCCCATGCCACAGCCCTGT
TATTGCATGGAAGCCTATCTTACAAAGGATGGCCCATTCCTGATGGTTGGCGATGCTGCAGGTGACATCTACACATTTACACTGCCTGGG
TTAAGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTACTTCTACACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGG
ACATACAGTCGTACCTTGCCACAGGTATTCCTCACAGAGTCCTTACTGAGACCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCA
CATAAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAA
TTTATCACCTTTGATCTAACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCAT
CTGAAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGC
TTCCTGCTGCAACGATTTGAGGACCATCAGGCAGCCATCAACAACTTCTGGGTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCT
GTGCACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCACCTGGAAAACACGTGGCATGATCACACAACA
GACAGCTGCATCTCCAGTGTGATGTGTGATAATGCAAGCATAGTACTTAGGGTGAGGAAAGTAAGTGACTCCAGCATTCTGGTGATGTAT

>In-frame_PBRM1_ENST00000410007_chr3_52595783_-_FBXW12_ENST00000415155_chr3_48416844_+_5143nt
TCCATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCA
GGCCCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGAC
TATAAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCT
CAGCCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTT
TTTAACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAAT
GAGTTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCA
GCTTACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAG
AAACTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAAT
GGAAGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTA
TTCAAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATG
AGGACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAG
TATTACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCT
GCTTTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTT
TATGACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGAT
TATTACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAG
TGTGATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTT
ATGCAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGT
GCCAAAAGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGC
AGAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAA
ATAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCAC
TATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCT
GATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAG
CAGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCT
AGATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAA
GATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCT
CTTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAA
GAGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCT
GTGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTA
TTTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAG
CAGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCAT
AATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAA
AAGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCAT
GTTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGAA
AAAGAAGTTTTTAAGAGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTT
AAGTTATGCCCAGAAAACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAA
CTGTGGACCATGCCCATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCA
GATAAAGGTGATGATGAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTC
CCTGTGGAAATGTCCAATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTC
TTCATCAAGTCCCATGGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCC
ATCTTCATTCACCCAGAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGC
CCCATGACATGTATTCTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATT
CTGCTTTGTGAGAGCCGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTA
GATGATGAAATTTACTACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCT
AAATTTGCCGAGTTAGAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAG
CTTCAGACCCCCCTGGCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAG
GAAGGCTCCAAACGGAAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTAC
TCTTTCGGGGAGCTCAGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGCATTTGAGACGGAG
TTGGCTTATCTCTCAGGAAATAGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCC
TGGGATGTGCAAGAGGTTGGCGATGCTGCAGGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAAGTTACTGCATTT
CAATATGGTATTGTACTTCTACACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTGCCACAGGTATTC
CTCACAGAGTCCTTACTGAGACCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGCGCCTGCTGGACC
CCAAAGGTGAAAAACAGGATAACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTAACAACCAAGAAG
ACTGGAGGCCAAACAGTCATCCAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGGATGGGAGCCAGT
GATGGATATATGATTGTCTTTACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTTGAGGACCATCAG
GCAGCCATCAACAACTTCTGGGTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGGGAAGAAGGAGGC
CGCCATCCATACCTCAGGAGCTGCTGTCACCTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGTGTGATGTGTGAT
AATGCAAGCATAGTACTTAGGGTGAGGAAAGTAAGTGACTCCAGCATTCTGGTGATGTATTCTTTGAATACGTAATATGGAAACTAACAA

>In-frame_PBRM1_ENST00000410007_chr3_52595783_-_FBXW12_ENST00000445170_chr3_48416844_+_5353nt
TCCATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCA
GGCCCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGAC
TATAAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCT
CAGCCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTT
TTTAACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAAT
GAGTTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCA
GCTTACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAG
AAACTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAAT
GGAAGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTA
TTCAAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATG
AGGACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAG
TATTACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCT
GCTTTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTT
TATGACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGAT
TATTACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAG
TGTGATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTT
ATGCAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGT
GCCAAAAGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGC
AGAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAA
ATAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCAC
TATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCT
GATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAG
CAGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCT
AGATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAA
GATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCT
CTTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAA
GAGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCT
GTGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTA
TTTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAG
CAGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCAT
AATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAA
AAGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCAT
GTTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGAA
AAAGAAGTTTTTAAGAGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTT
AAGTTATGCCCAGAAAACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAA
CTGTGGACCATGCCCATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCA
GATAAAGGTGATGATGAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTC
CCTGTGGAAATGTCCAATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTC
TTCATCAAGTCCCATGGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCC
ATCTTCATTCACCCAGAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGC
CCCATGACATGTATTCTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATT
CTGCTTTGTGAGAGCCGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTA
GATGATGAAATTTACTACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCT
AAATTTGCCGAGTTAGAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAG
CTTCAGACCCCCCTGGCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAG
GAAGGCTCCAAACGGAAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTAC
TCTTTCGGGGAGCTCAGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGCATTTGAGACGGAG
TTGGCTTATCTCTCAGGAAATAGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCC
TGGGATGTGCAAGAGGGTACCATGATCTGGTCAAGCCCAGTCCAGGAGTTCCATTTCTCAAATCTGGTAACCCTCCCTCAGATGCATCTC
GCCATCACTATGGATCGGAAAAAAACTATCAAAGTGTGGAACTGTCAGGACAGGGACGCTCTGGCTGTTCTCCCCATGCCACAGCCCTGT
TATTGCATGGAAGCCTATCTTACAAAGGATGGCCCATTCCTGATGGTTGGCGATGCTGCAGGTGACATCTACACATTTACACTGCCTGGG
TTAAGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTACTTCTACACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGG
ACATACAGTCGTACCTTGCCACAGGTATTCCTCACAGAGTCCTTACTGAGACCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCA
CATAAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAA
TTTATCACCTTTGATCTAACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCAT
CTGAAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGC
TTCCTGCTGCAACGATTTGAGGACCATCAGGCAGCCATCAACAACTTCTGGGTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCT
GTGCACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCACCTGGAAAACACGTGGCATGATCACACAACA
GACAGCTGCATCTCCAGTGTGATGTGTGATAATGCAAGCATAGTACTTAGGGTGAGGAAAGTAAGTGACTCCAGCATTCTGGTGATGTAT

>In-frame_PBRM1_ENST00000409057_chr3_52595783_-_FBXW12_ENST00000296438_chr3_48416844_+_5466nt
TCCATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCA
GGCCCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGAC
TATAAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCT
CAGCCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTT
TTTAACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAAT
GAGTTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCA
GCTTACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAG
AAACTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAAT
GGAAGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTA
TTCAAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATG
AGGACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAG
TATTACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCT
GCTTTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTT
TATGACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGAT
TATTACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAG
TGTGATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTT
ATGCAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGT
GCCAAAAGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGC
AGAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAA
ATAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCAC
TATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCT
GATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAG
CAGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCT
AGATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAA
GATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCT
CTTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAA
GAGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCT
GTGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTA
TTTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAG
CAGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCAT
AATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAA
AAGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCAT
GTTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGT
GAAAAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAG
AGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAA
AACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCC
ATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGAT
GAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCC
AATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCAT
GGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCA
GAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATT
CTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGC
CGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTAC
TACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTA
GAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTG
GCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGG
AAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTC
AGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGCATTTGAGACGGAGTTGGCTTATCTCTCA
GGAAATAGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAG
GGTACCATGATCTGGTCAAGCCCAGTCCAGGAGTTCCATTTCTCAAATCTGGTAACCCTCCCTCAGATGCATCTCGCCATCACTATGGAT
CGGAAAAAAACTATCAAAGTGTGGAACTGTCAGGACAGGGACGCTCTGGCTGTTCTCCCCATGCCACAGCCCTGTTATTGCATGGAAGCC
TATCTTACAAAGGATGGCCCATTCCTGATGGTTGGCGATGCTGCAGGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCT
AAAGTTACTGCATTTCAATATGGTATTGTACTTCTACACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACC
TTGCCACAGGTATTCCTCACAGAGTCCTTACTGAGACCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCC
AGCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGAT
CTAACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATC
TGGATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGA
TTTGAGGACCATCAGGCAGCCATCAACAACTTCTGGGTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATG
TGGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCACCTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCC
AGTGTGATGTGTGATAATGCAAGCATAGTACTTAGGGTGAGGAAAGTAAGTGACTCCAGCATTCTGGTGATGTATTCTTTGAATACGTAA

>In-frame_PBRM1_ENST00000409057_chr3_52595783_-_FBXW12_ENST00000415155_chr3_48416844_+_5218nt
TCCATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCA
GGCCCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGAC
TATAAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCT
CAGCCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTT
TTTAACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAAT
GAGTTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCA
GCTTACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAG
AAACTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAAT
GGAAGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTA
TTCAAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATG
AGGACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAG
TATTACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCT
GCTTTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTT
TATGACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGAT
TATTACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAG
TGTGATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTT
ATGCAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGT
GCCAAAAGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGC
AGAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAA
ATAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCAC
TATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCT
GATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAG
CAGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCT
AGATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAA
GATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCT
CTTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAA
GAGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCT
GTGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTA
TTTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAG
CAGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCAT
AATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAA
AAGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCAT
GTTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGT
GAAAAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAG
AGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAA
AACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCC
ATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGAT
GAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCC
AATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCAT
GGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCA
GAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATT
CTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGC
CGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTAC
TACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTA
GAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTG
GCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGG
AAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTC
AGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGCATTTGAGACGGAGTTGGCTTATCTCTCA
GGAAATAGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAG
GTTGGCGATGCTGCAGGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTA
CTTCTACACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTGCCACAGGTATTCCTCACAGAGTCCTTA
CTGAGACCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAAC
AGGATAACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTAACAACCAAGAAGACTGGAGGCCAAACA
GTCATCCAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATT
GTCTTTACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTTGAGGACCATCAGGCAGCCATCAACAAC
TTCTGGGTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTC
AGGAGCTGCTGTCACCTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGTGTGATGTGTGATAATGCAAGCATAGTA

>In-frame_PBRM1_ENST00000409057_chr3_52595783_-_FBXW12_ENST00000445170_chr3_48416844_+_5428nt
TCCATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCA
GGCCCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGAC
TATAAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCT
CAGCCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTT
TTTAACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAAT
GAGTTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCA
GCTTACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAG
AAACTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAAT
GGAAGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTA
TTCAAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATG
AGGACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAG
TATTACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCT
GCTTTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTT
TATGACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGAT
TATTACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAG
TGTGATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTT
ATGCAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGT
GCCAAAAGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGC
AGAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAA
ATAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCAC
TATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCT
GATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAG
CAGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCT
AGATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAA
GATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCT
CTTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAA
GAGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCT
GTGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTA
TTTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAG
CAGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCAT
AATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAA
AAGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCAT
GTTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGT
GAAAAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAG
AGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAA
AACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCC
ATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGAT
GAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCC
AATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCAT
GGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCA
GAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATT
CTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGC
CGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTAC
TACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTA
GAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTG
GCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGG
AAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTC
AGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGCATTTGAGACGGAGTTGGCTTATCTCTCA
GGAAATAGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAG
GGTACCATGATCTGGTCAAGCCCAGTCCAGGAGTTCCATTTCTCAAATCTGGTAACCCTCCCTCAGATGCATCTCGCCATCACTATGGAT
CGGAAAAAAACTATCAAAGTGTGGAACTGTCAGGACAGGGACGCTCTGGCTGTTCTCCCCATGCCACAGCCCTGTTATTGCATGGAAGCC
TATCTTACAAAGGATGGCCCATTCCTGATGGTTGGCGATGCTGCAGGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCT
AAAGTTACTGCATTTCAATATGGTATTGTACTTCTACACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACC
TTGCCACAGGTATTCCTCACAGAGTCCTTACTGAGACCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCC
AGCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGAT
CTAACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATC
TGGATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGA
TTTGAGGACCATCAGGCAGCCATCAACAACTTCTGGGTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATG
TGGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCACCTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCC
AGTGTGATGTGTGATAATGCAAGCATAGTACTTAGGGTGAGGAAAGTAAGTGACTCCAGCATTCTGGTGATGTATTCTTTGAATACGTAA

>In-frame_PBRM1_ENST00000409114_chr3_52595783_-_FBXW12_ENST00000296438_chr3_48416844_+_5511nt
TCCATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCA
GGCCCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGAC
TATAAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCT
CAGCCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTT
TTTAACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAAT
GAGTTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCA
GCTTACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAG
AAACTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAAT
GGAAGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTA
TTCAAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATG
AGGACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAG
TATTACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCT
GCTTTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTT
TATGACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGAT
TATTACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAG
TGTGATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTT
ATGCAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGT
GCCAAAAGAAAAAGGAACACTCATGACAGTGAGATGTTGGGTCTCAGGAGGCTATCCAGTAAAAAGAACATAAGAAAGCAGCGAATGAAA
ATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGAC
TATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAG
GGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTG
GAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAG
AGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGAT
AAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATG
GACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAAT
GCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAG
GGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGAT
GATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATA
ATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATG
AATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAG
ATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATA
GAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACAT
CGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAA
CCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAAAAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACA
TTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAG
TGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCT
GCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTG
GTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAAT
TTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAAT
GACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTT
CGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAA
GTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGC
AGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTG
AAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTG
CTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGT
GAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACC
CCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGG
GCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAG
AAAGCAGAATATGAAGCATTTGAGACGGAGTTGGCTTATCTCTCAGGAAATAGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGT
AGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGGTACCATGATCTGGTCAAGCCCAGTCCAGGAGTTCCATTTCTCA
AATCTGGTAACCCTCCCTCAGATGCATCTCGCCATCACTATGGATCGGAAAAAAACTATCAAAGTGTGGAACTGTCAGGACAGGGACGCT
CTGGCTGTTCTCCCCATGCCACAGCCCTGTTATTGCATGGAAGCCTATCTTACAAAGGATGGCCCATTCCTGATGGTTGGCGATGCTGCA
GGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTACTTCTACACTGCTCT
CCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTGCCACAGGTATTCCTCACAGAGTCCTTACTGAGACCATCAGAA
GGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTGATG
TCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTAACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCATAT
GAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGTGGA
CCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTTGAGGACCATCAGGCAGCCATCAACAACTTCTGGGTGGATCCT
TGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCAC
CTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGTGTGATGTGTGATAATGCAAGCATAGTACTTAGGGTGAGGAAA
GTAAGTGACTCCAGCATTCTGGTGATGTATTCTTTGAATACGTAATATGGAAACTAACAAAATTGACCTTGCATCATCTTCTGCAATGTA

>In-frame_PBRM1_ENST00000409114_chr3_52595783_-_FBXW12_ENST00000415155_chr3_48416844_+_5263nt
TCCATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCA
GGCCCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGAC
TATAAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCT
CAGCCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTT
TTTAACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAAT
GAGTTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCA
GCTTACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAG
AAACTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAAT
GGAAGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTA
TTCAAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATG
AGGACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAG
TATTACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCT
GCTTTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTT
TATGACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGAT
TATTACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAG
TGTGATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTT
ATGCAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGT
GCCAAAAGAAAAAGGAACACTCATGACAGTGAGATGTTGGGTCTCAGGAGGCTATCCAGTAAAAAGAACATAAGAAAGCAGCGAATGAAA
ATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGAC
TATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAG
GGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTG
GAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAG
AGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGAT
AAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATG
GACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAAT
GCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAG
GGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGAT
GATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATA
ATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATG
AATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAG
ATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATA
GAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACAT
CGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAA
CCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAAAAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACA
TTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAG
TGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCT
GCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTG
GTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAAT
TTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAAT
GACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTT
CGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAA
GTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGC
AGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTG
AAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTG
CTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGT
GAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACC
CCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGG
GCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAG
AAAGCAGAATATGAAGCATTTGAGACGGAGTTGGCTTATCTCTCAGGAAATAGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGT
AGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGTTGGCGATGCTGCAGGTGACATCTACACATTTACACTGCCTGGG
TTAAGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTACTTCTACACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGG
ACATACAGTCGTACCTTGCCACAGGTATTCCTCACAGAGTCCTTACTGAGACCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCA
CATAAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAA
TTTATCACCTTTGATCTAACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCAT
CTGAAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGC
TTCCTGCTGCAACGATTTGAGGACCATCAGGCAGCCATCAACAACTTCTGGGTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCT
GTGCACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCACCTGGAAAACACGTGGCATGATCACACAACA
GACAGCTGCATCTCCAGTGTGATGTGTGATAATGCAAGCATAGTACTTAGGGTGAGGAAAGTAAGTGACTCCAGCATTCTGGTGATGTAT

>In-frame_PBRM1_ENST00000409114_chr3_52595783_-_FBXW12_ENST00000445170_chr3_48416844_+_5473nt
TCCATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCA
GGCCCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGAC
TATAAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCT
CAGCCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTT
TTTAACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAAT
GAGTTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCA
GCTTACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAG
AAACTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAAT
GGAAGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTA
TTCAAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATG
AGGACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAG
TATTACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCT
GCTTTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTT
TATGACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGAT
TATTACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAG
TGTGATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTT
ATGCAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGT
GCCAAAAGAAAAAGGAACACTCATGACAGTGAGATGTTGGGTCTCAGGAGGCTATCCAGTAAAAAGAACATAAGAAAGCAGCGAATGAAA
ATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGAC
TATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAG
GGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTG
GAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAG
AGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGAT
AAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATG
GACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAAT
GCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAG
GGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGAT
GATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATA
ATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATG
AATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAG
ATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATA
GAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACAT
CGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAA
CCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAAAAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACA
TTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAG
TGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCT
GCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTG
GTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAAT
TTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAAT
GACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTT
CGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAA
GTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGC
AGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTG
AAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTG
CTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGT
GAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACC
CCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGG
GCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAG
AAAGCAGAATATGAAGCATTTGAGACGGAGTTGGCTTATCTCTCAGGAAATAGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGT
AGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGGTACCATGATCTGGTCAAGCCCAGTCCAGGAGTTCCATTTCTCA
AATCTGGTAACCCTCCCTCAGATGCATCTCGCCATCACTATGGATCGGAAAAAAACTATCAAAGTGTGGAACTGTCAGGACAGGGACGCT
CTGGCTGTTCTCCCCATGCCACAGCCCTGTTATTGCATGGAAGCCTATCTTACAAAGGATGGCCCATTCCTGATGGTTGGCGATGCTGCA
GGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTACTTCTACACTGCTCT
CCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTGCCACAGGTATTCCTCACAGAGTCCTTACTGAGACCATCAGAA
GGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTGATG
TCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTAACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCATAT
GAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGTGGA
CCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTTGAGGACCATCAGGCAGCCATCAACAACTTCTGGGTGGATCCT
TGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCAC
CTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGTGTGATGTGTGATAATGCAAGCATAGTACTTAGGGTGAGGAAA

>In-frame_PBRM1_ENST00000409767_chr3_52595783_-_FBXW12_ENST00000296438_chr3_48416844_+_5511nt
TCCATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCA
GGCCCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGAC
TATAAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCT
CAGCCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTT
TTTAACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAAT
GAGTTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCA
GCTTACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAG
AAACTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAAT
GGAAGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTA
TTCAAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATG
AGGACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAG
TATTACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCT
GCTTTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTT
TATGACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGAT
TATTACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAG
TGTGATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTT
ATGCAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGT
GCCAAAAGAAAAAGGAACACTCATGACAGTGAGATGTTGGGTCTCAGGAGGCTATCCAGTAAAAAGAACATAAGAAAGCAGCGAATGAAA
ATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGAC
TATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAG
GGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTG
GAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAG
AGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGAT
AAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATG
GACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAAT
GCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAG
GGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGAT
GATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATA
ATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATG
AATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAG
ATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATA
GAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACAT
CGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAA
CCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAAAAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACA
TTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAG
TGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCT
GCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTG
GTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAAT
TTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAAT
GACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTT
CGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAA
GTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGC
AGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTG
AAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTG
CTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGT
GAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACC
CCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGG
GCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAG
AAAGCAGAATATGAAGCATTTGAGACGGAGTTGGCTTATCTCTCAGGAAATAGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGT
AGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGGTACCATGATCTGGTCAAGCCCAGTCCAGGAGTTCCATTTCTCA
AATCTGGTAACCCTCCCTCAGATGCATCTCGCCATCACTATGGATCGGAAAAAAACTATCAAAGTGTGGAACTGTCAGGACAGGGACGCT
CTGGCTGTTCTCCCCATGCCACAGCCCTGTTATTGCATGGAAGCCTATCTTACAAAGGATGGCCCATTCCTGATGGTTGGCGATGCTGCA
GGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTACTTCTACACTGCTCT
CCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTGCCACAGGTATTCCTCACAGAGTCCTTACTGAGACCATCAGAA
GGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTGATG
TCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTAACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCATAT
GAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGTGGA
CCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTTGAGGACCATCAGGCAGCCATCAACAACTTCTGGGTGGATCCT
TGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCAC
CTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGTGTGATGTGTGATAATGCAAGCATAGTACTTAGGGTGAGGAAA
GTAAGTGACTCCAGCATTCTGGTGATGTATTCTTTGAATACGTAATATGGAAACTAACAAAATTGACCTTGCATCATCTTCTGCAATGTA

>In-frame_PBRM1_ENST00000409767_chr3_52595783_-_FBXW12_ENST00000415155_chr3_48416844_+_5263nt
TCCATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCA
GGCCCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGAC
TATAAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCT
CAGCCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTT
TTTAACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAAT
GAGTTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCA
GCTTACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAG
AAACTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAAT
GGAAGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTA
TTCAAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATG
AGGACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAG
TATTACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCT
GCTTTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTT
TATGACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGAT
TATTACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAG
TGTGATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTT
ATGCAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGT
GCCAAAAGAAAAAGGAACACTCATGACAGTGAGATGTTGGGTCTCAGGAGGCTATCCAGTAAAAAGAACATAAGAAAGCAGCGAATGAAA
ATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGAC
TATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAG
GGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTG
GAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAG
AGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGAT
AAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATG
GACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAAT
GCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAG
GGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGAT
GATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATA
ATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATG
AATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAG
ATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATA
GAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACAT
CGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAA
CCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAAAAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACA
TTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAG
TGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCT
GCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTG
GTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAAT
TTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAAT
GACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTT
CGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAA
GTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGC
AGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTG
AAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTG
CTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGT
GAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACC
CCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGG
GCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAG
AAAGCAGAATATGAAGCATTTGAGACGGAGTTGGCTTATCTCTCAGGAAATAGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGT
AGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGTTGGCGATGCTGCAGGTGACATCTACACATTTACACTGCCTGGG
TTAAGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTACTTCTACACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGG
ACATACAGTCGTACCTTGCCACAGGTATTCCTCACAGAGTCCTTACTGAGACCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCA
CATAAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAA
TTTATCACCTTTGATCTAACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCAT
CTGAAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGC
TTCCTGCTGCAACGATTTGAGGACCATCAGGCAGCCATCAACAACTTCTGGGTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCT
GTGCACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCACCTGGAAAACACGTGGCATGATCACACAACA
GACAGCTGCATCTCCAGTGTGATGTGTGATAATGCAAGCATAGTACTTAGGGTGAGGAAAGTAAGTGACTCCAGCATTCTGGTGATGTAT

>In-frame_PBRM1_ENST00000409767_chr3_52595783_-_FBXW12_ENST00000445170_chr3_48416844_+_5473nt
TCCATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCA
GGCCCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGAC
TATAAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCT
CAGCCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTT
TTTAACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAAT
GAGTTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCA
GCTTACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAG
AAACTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAAT
GGAAGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTA
TTCAAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATG
AGGACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAG
TATTACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCT
GCTTTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTT
TATGACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGAT
TATTACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAG
TGTGATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTT
ATGCAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGT
GCCAAAAGAAAAAGGAACACTCATGACAGTGAGATGTTGGGTCTCAGGAGGCTATCCAGTAAAAAGAACATAAGAAAGCAGCGAATGAAA
ATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGAC
TATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAG
GGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTG
GAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAG
AGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGAT
AAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATG
GACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAAT
GCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAG
GGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGAT
GATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATA
ATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATG
AATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAG
ATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATA
GAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACAT
CGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAA
CCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAAAAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACA
TTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAG
TGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCT
GCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTG
GTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAAT
TTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAAT
GACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTT
CGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAA
GTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGC
AGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTG
AAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTG
CTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGT
GAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACC
CCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGG
GCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAG
AAAGCAGAATATGAAGCATTTGAGACGGAGTTGGCTTATCTCTCAGGAAATAGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGT
AGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGGTACCATGATCTGGTCAAGCCCAGTCCAGGAGTTCCATTTCTCA
AATCTGGTAACCCTCCCTCAGATGCATCTCGCCATCACTATGGATCGGAAAAAAACTATCAAAGTGTGGAACTGTCAGGACAGGGACGCT
CTGGCTGTTCTCCCCATGCCACAGCCCTGTTATTGCATGGAAGCCTATCTTACAAAGGATGGCCCATTCCTGATGGTTGGCGATGCTGCA
GGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTACTTCTACACTGCTCT
CCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTGCCACAGGTATTCCTCACAGAGTCCTTACTGAGACCATCAGAA
GGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTGATG
TCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTAACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCATAT
GAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGTGGA
CCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTTGAGGACCATCAGGCAGCCATCAACAACTTCTGGGTGGATCCT
TGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCAC
CTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGTGTGATGTGTGATAATGCAAGCATAGTACTTAGGGTGAGGAAA

>In-frame_PBRM1_ENST00000296302_chr3_52592265_-_FBXW12_ENST00000296438_chr3_48416844_+_5630nt
CCATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAG
GCCCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACT
ATAAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCTC
AGCCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTTT
TTAACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAATG
AGTTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCAG
CTTACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAGA
AACTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAATG
GAAGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTAT
TCAAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATGA
GGACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAGT
ATTACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCTG
CTTTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTTT
ATGACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGATT
ATTACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGT
GTGATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTA
TGCAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTG
CCAAAAGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCA
GAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAA
TAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACT
ATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTG
ATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGC
AGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTA
GATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAG
ATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTC
TTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAG
AGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTG
TGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTAT
TTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGC
AGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATA
ATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAA
AGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATG
TTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTG
AAAAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGA
GTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAA
ACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCA
TCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATG
AGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCA
ATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATG
GCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAG
AAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTC
TCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCC
GCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACT
ACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAG
AAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGG
CCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGA
AAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCA
GCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGAGCGGGCAGCTAAAGTTGCTGAGCAGCAGG
AGAGAGAGCGAGCAGCACAGCAACAGCAGCCGAGTGCTTCTCCCCGAGCAGGCACCCCTGTGGGGGCTCTCATGGGGGTGGTGCCACCAC
CAACACCAATGGGGATGCTCAATCAGCAGTTGACACCTGTTGCAGCATTTGAGACGGAGTTGGCTTATCTCTCAGGAAATAGACTTACAG
TGGATGAACAGGAGAAATCAATCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGGTACCATGATCTGGT
CAAGCCCAGTCCAGGAGTTCCATTTCTCAAATCTGGTAACCCTCCCTCAGATGCATCTCGCCATCACTATGGATCGGAAAAAAACTATCA
AAGTGTGGAACTGTCAGGACAGGGACGCTCTGGCTGTTCTCCCCATGCCACAGCCCTGTTATTGCATGGAAGCCTATCTTACAAAGGATG
GCCCATTCCTGATGGTTGGCGATGCTGCAGGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAAGTTACTGCATTTC
AATATGGTATTGTACTTCTACACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTGCCACAGGTATTCC
TCACAGAGTCCTTACTGAGACCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGCGCCTGCTGGACCC
CAAAGGTGAAAAACAGGATAACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTAACAACCAAGAAGA
CTGGAGGCCAAACAGTCATCCAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGGATGGGAGCCAGTG
ATGGATATATGATTGTCTTTACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTTGAGGACCATCAGG
CAGCCATCAACAACTTCTGGGTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGGGAAGAAGGAGGCC
GCCATCCATACCTCAGGAGCTGCTGTCACCTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGTGTGATGTGTGATA
ATGCAAGCATAGTACTTAGGGTGAGGAAAGTAAGTGACTCCAGCATTCTGGTGATGTATTCTTTGAATACGTAATATGGAAACTAACAAA

>In-frame_PBRM1_ENST00000296302_chr3_52592265_-_FBXW12_ENST00000415155_chr3_48416844_+_5382nt
CCATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAG
GCCCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACT
ATAAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCTC
AGCCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTTT
TTAACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAATG
AGTTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCAG
CTTACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAGA
AACTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAATG
GAAGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTAT
TCAAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATGA
GGACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAGT
ATTACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCTG
CTTTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTTT
ATGACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGATT
ATTACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGT
GTGATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTA
TGCAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTG
CCAAAAGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCA
GAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAA
TAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACT
ATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTG
ATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGC
AGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTA
GATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAG
ATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTC
TTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAG
AGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTG
TGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTAT
TTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGC
AGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATA
ATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAA
AGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATG
TTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTG
AAAAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGA
GTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAA
ACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCA
TCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATG
AGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCA
ATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATG
GCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAG
AAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTC
TCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCC
GCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACT
ACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAG
AAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGG
CCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGA
AAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCA
GCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGAGCGGGCAGCTAAAGTTGCTGAGCAGCAGG
AGAGAGAGCGAGCAGCACAGCAACAGCAGCCGAGTGCTTCTCCCCGAGCAGGCACCCCTGTGGGGGCTCTCATGGGGGTGGTGCCACCAC
CAACACCAATGGGGATGCTCAATCAGCAGTTGACACCTGTTGCAGCATTTGAGACGGAGTTGGCTTATCTCTCAGGAAATAGACTTACAG
TGGATGAACAGGAGAAATCAATCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGTTGGCGATGCTGCAG
GTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTACTTCTACACTGCTCTC
CTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTGCCACAGGTATTCCTCACAGAGTCCTTACTGAGACCATCAGAAG
GCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTGATGT
CCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTAACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCATATG
AGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGTGGAC
CATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTTGAGGACCATCAGGCAGCCATCAACAACTTCTGGGTGGATCCTT
GCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCACC
TGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGTGTGATGTGTGATAATGCAAGCATAGTACTTAGGGTGAGGAAAG

>In-frame_PBRM1_ENST00000296302_chr3_52592265_-_FBXW12_ENST00000445170_chr3_48416844_+_5592nt
CCATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAG
GCCCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACT
ATAAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCTC
AGCCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTTT
TTAACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAATG
AGTTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCAG
CTTACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAGA
AACTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAATG
GAAGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTAT
TCAAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATGA
GGACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAGT
ATTACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCTG
CTTTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTTT
ATGACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGATT
ATTACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGT
GTGATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTA
TGCAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTG
CCAAAAGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCA
GAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAA
TAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACT
ATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTG
ATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGC
AGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTA
GATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAG
ATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTC
TTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAG
AGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTG
TGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTAT
TTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGC
AGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATA
ATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAA
AGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATG
TTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTG
AAAAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGA
GTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAA
ACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCA
TCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATG
AGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCA
ATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATG
GCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAG
AAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTC
TCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCC
GCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACT
ACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAG
AAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGG
CCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGA
AAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCA
GCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGAGCGGGCAGCTAAAGTTGCTGAGCAGCAGG
AGAGAGAGCGAGCAGCACAGCAACAGCAGCCGAGTGCTTCTCCCCGAGCAGGCACCCCTGTGGGGGCTCTCATGGGGGTGGTGCCACCAC
CAACACCAATGGGGATGCTCAATCAGCAGTTGACACCTGTTGCAGCATTTGAGACGGAGTTGGCTTATCTCTCAGGAAATAGACTTACAG
TGGATGAACAGGAGAAATCAATCATTTGTAGTGTATCTCCAAAGCAAGAGCTTTGTGCCTGGGATGTGCAAGAGGGTACCATGATCTGGT
CAAGCCCAGTCCAGGAGTTCCATTTCTCAAATCTGGTAACCCTCCCTCAGATGCATCTCGCCATCACTATGGATCGGAAAAAAACTATCA
AAGTGTGGAACTGTCAGGACAGGGACGCTCTGGCTGTTCTCCCCATGCCACAGCCCTGTTATTGCATGGAAGCCTATCTTACAAAGGATG
GCCCATTCCTGATGGTTGGCGATGCTGCAGGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCTAAAGTTACTGCATTTC
AATATGGTATTGTACTTCTACACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACCTTGCCACAGGTATTCC
TCACAGAGTCCTTACTGAGACCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCCAGCGCCTGCTGGACCC
CAAAGGTGAAAAACAGGATAACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGATCTAACAACCAAGAAGA
CTGGAGGCCAAACAGTCATCCAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATCTGGATGGGAGCCAGTG
ATGGATATATGATTGTCTTTACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGATTTGAGGACCATCAGG
CAGCCATCAACAACTTCTGGGTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATGTGGGAAGAAGGAGGCC
GCCATCCATACCTCAGGAGCTGCTGTCACCTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCCAGTGTGATGTGTGATA
ATGCAAGCATAGTACTTAGGGTGAGGAAAGTAAGTGACTCCAGCATTCTGGTGATGTATTCTTTGAATACGTAATATGGAAACTAACAAA

>In-frame_PBRM1_ENST00000409114_chr3_52592265_-_FBXW12_ENST00000296438_chr3_48416844_+_5676nt
TCCATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCA
GGCCCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGAC
TATAAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCT
CAGCCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTT
TTTAACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAAT
GAGTTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCA
GCTTACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAG
AAACTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAAT
GGAAGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTA
TTCAAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATG
AGGACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAG
TATTACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCT
GCTTTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTT
TATGACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGAT
TATTACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAG
TGTGATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTT
ATGCAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGT
GCCAAAAGAAAAAGGAACACTCATGACAGTGAGATGTTGGGTCTCAGGAGGCTATCCAGTAAAAAGAACATAAGAAAGCAGCGAATGAAA
ATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGAC
TATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAG
GGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTG
GAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAG
AGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGAT
AAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATG
GACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAAT
GCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAG
GGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGAT
GATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATA
ATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATG
AATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAG
ATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATA
GAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACAT
CGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAA
CCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAAAAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACA
TTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAG
TGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCT
GCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTG
GTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAAT
TTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAAT
GACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTT
CGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAA
GTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGC
AGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTG
AAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTG
CTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGT
GAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACC
CCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGG
GCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAG
AAAGCAGAATATGAAGAGCGGGCAGCTAAAGTTGCTGAGCAGCAGGAGAGAGAGCGAGCAGCACAGCAACAGCAGCCGAGTGCTTCTCCC
CGAGCAGGCACCCCTGTGGGGGCTCTCATGGGGGTGGTGCCACCACCAACACCAATGGGGATGCTCAATCAGCAGTTGACACCTGTTGCA
GCATTTGAGACGGAGTTGGCTTATCTCTCAGGAAATAGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGTAGTGTATCTCCAAAG
CAAGAGCTTTGTGCCTGGGATGTGCAAGAGGGTACCATGATCTGGTCAAGCCCAGTCCAGGAGTTCCATTTCTCAAATCTGGTAACCCTC
CCTCAGATGCATCTCGCCATCACTATGGATCGGAAAAAAACTATCAAAGTGTGGAACTGTCAGGACAGGGACGCTCTGGCTGTTCTCCCC
ATGCCACAGCCCTGTTATTGCATGGAAGCCTATCTTACAAAGGATGGCCCATTCCTGATGGTTGGCGATGCTGCAGGTGACATCTACACA
TTTACACTGCCTGGGTTAAGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTACTTCTACACTGCTCTCCTGACAAGAAATGG
GTATTTGCATGTGGGACATACAGTCGTACCTTGCCACAGGTATTCCTCACAGAGTCCTTACTGAGACCATCAGAAGGCAGTGTTCCTCTG
TCTACCTTTCTCCCACATAAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTGATGTCCCAAAGTAGCACT
GGAAAAAAGACAGAATTTATCACCTTTGATCTAACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCATATGAGATCGCAAGTTTC
CAGGTGGCAGCTCATCTGAAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGTGGACCATACTTGTTACTC
TTCAGCATCACTGGCTTCCTGCTGCAACGATTTGAGGACCATCAGGCAGCCATCAACAACTTCTGGGTGGATCCTTGCTATGTGCTCACC
ACATCCGAGAACTCTGTGCACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCACCTGGAAAACACGTGG
CATGATCACACAACAGACAGCTGCATCTCCAGTGTGATGTGTGATAATGCAAGCATAGTACTTAGGGTGAGGAAAGTAAGTGACTCCAGC
ATTCTGGTGATGTATTCTTTGAATACGTAATATGGAAACTAACAAAATTGACCTTGCATCATCTTCTGCAATGTAGTAAAGAAATTCTAT

>In-frame_PBRM1_ENST00000409114_chr3_52592265_-_FBXW12_ENST00000415155_chr3_48416844_+_5428nt
TCCATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCA
GGCCCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGAC
TATAAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCT
CAGCCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTT
TTTAACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAAT
GAGTTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCA
GCTTACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAG
AAACTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAAT
GGAAGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTA
TTCAAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATG
AGGACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAG
TATTACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCT
GCTTTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTT
TATGACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGAT
TATTACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAG
TGTGATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTT
ATGCAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGT
GCCAAAAGAAAAAGGAACACTCATGACAGTGAGATGTTGGGTCTCAGGAGGCTATCCAGTAAAAAGAACATAAGAAAGCAGCGAATGAAA
ATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGAC
TATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAG
GGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTG
GAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAG
AGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGAT
AAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATG
GACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAAT
GCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAG
GGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGAT
GATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATA
ATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATG
AATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAG
ATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATA
GAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACAT
CGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAA
CCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAAAAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACA
TTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAG
TGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCT
GCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTG
GTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAAT
TTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAAT
GACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTT
CGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAA
GTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGC
AGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTG
AAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTG
CTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGT
GAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACC
CCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGG
GCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAG
AAAGCAGAATATGAAGAGCGGGCAGCTAAAGTTGCTGAGCAGCAGGAGAGAGAGCGAGCAGCACAGCAACAGCAGCCGAGTGCTTCTCCC
CGAGCAGGCACCCCTGTGGGGGCTCTCATGGGGGTGGTGCCACCACCAACACCAATGGGGATGCTCAATCAGCAGTTGACACCTGTTGCA
GCATTTGAGACGGAGTTGGCTTATCTCTCAGGAAATAGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGTAGTGTATCTCCAAAG
CAAGAGCTTTGTGCCTGGGATGTGCAAGAGGTTGGCGATGCTGCAGGTGACATCTACACATTTACACTGCCTGGGTTAAGAGATGTTTCT
AAAGTTACTGCATTTCAATATGGTATTGTACTTCTACACTGCTCTCCTGACAAGAAATGGGTATTTGCATGTGGGACATACAGTCGTACC
TTGCCACAGGTATTCCTCACAGAGTCCTTACTGAGACCATCAGAAGGCAGTGTTCCTCTGTCTACCTTTCTCCCACATAAATTATGTGCC
AGCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTGATGTCCCAAAGTAGCACTGGAAAAAAGACAGAATTTATCACCTTTGAT
CTAACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCATATGAGATCGCAAGTTTCCAGGTGGCAGCTCATCTGAAGTGCCCTATC
TGGATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGTGGACCATACTTGTTACTCTTCAGCATCACTGGCTTCCTGCTGCAACGA
TTTGAGGACCATCAGGCAGCCATCAACAACTTCTGGGTGGATCCTTGCTATGTGCTCACCACATCCGAGAACTCTGTGCACGTGTACATG
TGGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCACCTGGAAAACACGTGGCATGATCACACAACAGACAGCTGCATCTCC
AGTGTGATGTGTGATAATGCAAGCATAGTACTTAGGGTGAGGAAAGTAAGTGACTCCAGCATTCTGGTGATGTATTCTTTGAATACGTAA

>In-frame_PBRM1_ENST00000409114_chr3_52592265_-_FBXW12_ENST00000445170_chr3_48416844_+_5638nt
TCCATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCA
GGCCCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGAC
TATAAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCT
CAGCCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTT
TTTAACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAAT
GAGTTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCA
GCTTACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAG
AAACTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAAT
GGAAGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTA
TTCAAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATG
AGGACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAG
TATTACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCT
GCTTTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTT
TATGACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGAT
TATTACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAG
TGTGATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTT
ATGCAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGT
GCCAAAAGAAAAAGGAACACTCATGACAGTGAGATGTTGGGTCTCAGGAGGCTATCCAGTAAAAAGAACATAAGAAAGCAGCGAATGAAA
ATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGAC
TATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAG
GGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTG
GAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAG
AGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGAT
AAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATG
GACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAAT
GCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAG
GGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGAT
GATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATA
ATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATG
AATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAG
ATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATA
GAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACAT
CGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAA
CCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAAAAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACA
TTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAG
TGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCT
GCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTG
GTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAAT
TTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAAT
GACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTT
CGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAA
GTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGC
AGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTG
AAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTG
CTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGT
GAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACC
CCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGG
GCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAG
AAAGCAGAATATGAAGAGCGGGCAGCTAAAGTTGCTGAGCAGCAGGAGAGAGAGCGAGCAGCACAGCAACAGCAGCCGAGTGCTTCTCCC
CGAGCAGGCACCCCTGTGGGGGCTCTCATGGGGGTGGTGCCACCACCAACACCAATGGGGATGCTCAATCAGCAGTTGACACCTGTTGCA
GCATTTGAGACGGAGTTGGCTTATCTCTCAGGAAATAGACTTACAGTGGATGAACAGGAGAAATCAATCATTTGTAGTGTATCTCCAAAG
CAAGAGCTTTGTGCCTGGGATGTGCAAGAGGGTACCATGATCTGGTCAAGCCCAGTCCAGGAGTTCCATTTCTCAAATCTGGTAACCCTC
CCTCAGATGCATCTCGCCATCACTATGGATCGGAAAAAAACTATCAAAGTGTGGAACTGTCAGGACAGGGACGCTCTGGCTGTTCTCCCC
ATGCCACAGCCCTGTTATTGCATGGAAGCCTATCTTACAAAGGATGGCCCATTCCTGATGGTTGGCGATGCTGCAGGTGACATCTACACA
TTTACACTGCCTGGGTTAAGAGATGTTTCTAAAGTTACTGCATTTCAATATGGTATTGTACTTCTACACTGCTCTCCTGACAAGAAATGG
GTATTTGCATGTGGGACATACAGTCGTACCTTGCCACAGGTATTCCTCACAGAGTCCTTACTGAGACCATCAGAAGGCAGTGTTCCTCTG
TCTACCTTTCTCCCACATAAATTATGTGCCAGCGCCTGCTGGACCCCAAAGGTGAAAAACAGGATAACACTGATGTCCCAAAGTAGCACT
GGAAAAAAGACAGAATTTATCACCTTTGATCTAACAACCAAGAAGACTGGAGGCCAAACAGTCATCCAAGCATATGAGATCGCAAGTTTC
CAGGTGGCAGCTCATCTGAAGTGCCCTATCTGGATGGGAGCCAGTGATGGATATATGATTGTCTTTACCAGTGGACCATACTTGTTACTC
TTCAGCATCACTGGCTTCCTGCTGCAACGATTTGAGGACCATCAGGCAGCCATCAACAACTTCTGGGTGGATCCTTGCTATGTGCTCACC
ACATCCGAGAACTCTGTGCACGTGTACATGTGGGAAGAAGGAGGCCGCCATCCATACCTCAGGAGCTGCTGTCACCTGGAAAACACGTGG
CATGATCACACAACAGACAGCTGCATCTCCAGTGTGATGTGTGATAATGCAAGCATAGTACTTAGGGTGAGGAAAGTAAGTGACTCCAGC


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FusionGenePPI for PBRM1_FBXW12


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
PBRM1ARID1A, SMARCC2, SMARCC1, SMARCE1, HIST1H3A, HIST1H4A, HIST2H2BE, HIST2H2AC, CHD7, ARID2, SMARCD1, ACTL6A, SMARCB1, SMARCA4, SMARCAD1, HIST3H3, SIRT7, CALML5, APP, GTF3C5, TCHHL1, NOTCH1, MAML1, ZNF512B, HECW2, CDC20, ZDHHC17, OBSL1, EED, DPF3, NUP50, COPS3, BRD7, SCARNA22, IFI16, HIST1H3E, DPPA4, NANOG, POU5F1, TOP1, HDAC6, VHL, BCL7C, BCL7A, ZBTB48, UHRF2, BRD1FBXW12IL22RA1, SKP1, TENC1


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for PBRM1_FBXW12


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for PBRM1_FBXW12


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgenePBRM1C0005586Bipolar Disorder3PSYGENET
HgenePBRM1C0007134Renal Cell Carcinoma2CTD_human
HgenePBRM1C0033975Psychotic Disorders1PSYGENET
HgenePBRM1C0036341Schizophrenia1PSYGENET
HgenePBRM1C0040100Thymoma1CTD_human
HgenePBRM1C0206698Cholangiocarcinoma1CTD_human
HgenePBRM1C0349204Nonorganic psychosis1PSYGENET