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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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Fusion gene ID: 26071

FusionGeneSummary for PAX3_NCOA1

check button Fusion gene summary
Fusion gene informationFusion gene name: PAX3_NCOA1
Fusion gene ID: 26071
HgeneTgene
Gene symbol

PAX3

NCOA1

Gene ID

5077

8648

Gene namepaired box 3nuclear receptor coactivator 1
SynonymsCDHS|HUP2|WS1|WS3F-SRC-1|KAT13A|RIP160|SRC1|bHLHe42|bHLHe74
Cytomap

2q36.1

2p23.3

Type of geneprotein-codingprotein-coding
Descriptionpaired box protein Pax-3paired box homeotic gene 3paired domain gene 3paired domain gene HuP2transcriptional factor PAX3nuclear receptor coactivator 1Hin-2 proteinclass E basic helix-loop-helix protein 74renal carcinoma antigen NY-REN-52steroid receptor coactivator-1
Modification date2018052220180523
UniProtAcc

P23760

Q15788

Ensembl transtripts involved in fusion geneENST00000392069, ENST00000344493, 
ENST00000350526, ENST00000336840, 
ENST00000392070, ENST00000409551, 
ENST00000464706, ENST00000409828, 
ENST00000258387, 		ENST00000406961, 
ENST00000469850, ENST00000405141, 
ENST00000407230, ENST00000538539, 
ENST00000288599, ENST00000348332, 
ENST00000395856, 
Fusion gene scores* DoF score4 X 4 X 1=167 X 7 X 3=147
# samples 88
** MAII scorelog2(8/16*10)=2.32192809488736
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(8/147*10)=-0.877744249949002
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PAX3 [Title/Abstract] AND NCOA1 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationOncogene involved fusion gene, in-frame and retained their domain.
Transcription factor involved fusion gene, inframe and retained DNA-binding domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgenePAX3

GO:0045893

positive regulation of transcription, DNA-templated

11863357

HgenePAX3

GO:0045944

positive regulation of transcription by RNA polymerase II

11863357

TgeneNCOA1

GO:0000435

positive regulation of transcription from RNA polymerase II promoter by galactose

10207113

TgeneNCOA1

GO:0006351

transcription, DNA-templated

9223431

TgeneNCOA1

GO:0045893

positive regulation of transcription, DNA-templated

11891224|15367689

TgeneNCOA1

GO:0045944

positive regulation of transcription by RNA polymerase II

15919756


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS3.1AY633656PAX3chr2

223085940

-NCOA1chr2

24949456

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000392069ENST00000406961PAX3chr2

223085940

-NCOA1chr2

24949456

+
5CDS-intronENST00000392069ENST00000469850PAX3chr2

223085940

-NCOA1chr2

24949456

+
5CDS-intronENST00000392069ENST00000405141PAX3chr2

223085940

-NCOA1chr2

24949456

+
5CDS-intronENST00000392069ENST00000407230PAX3chr2

223085940

-NCOA1chr2

24949456

+
5CDS-intronENST00000392069ENST00000538539PAX3chr2

223085940

-NCOA1chr2

24949456

+
5CDS-intronENST00000392069ENST00000288599PAX3chr2

223085940

-NCOA1chr2

24949456

+
5CDS-intronENST00000392069ENST00000348332PAX3chr2

223085940

-NCOA1chr2

24949456

+
5CDS-intronENST00000392069ENST00000395856PAX3chr2

223085940

-NCOA1chr2

24949456

+
In-frameENST00000344493ENST00000406961PAX3chr2

223085940

-NCOA1chr2

24949456

+
5CDS-intronENST00000344493ENST00000469850PAX3chr2

223085940

-NCOA1chr2

24949456

+
5CDS-intronENST00000344493ENST00000405141PAX3chr2

223085940

-NCOA1chr2

24949456

+
5CDS-intronENST00000344493ENST00000407230PAX3chr2

223085940

-NCOA1chr2

24949456

+
5CDS-intronENST00000344493ENST00000538539PAX3chr2

223085940

-NCOA1chr2

24949456

+
5CDS-intronENST00000344493ENST00000288599PAX3chr2

223085940

-NCOA1chr2

24949456

+
5CDS-intronENST00000344493ENST00000348332PAX3chr2

223085940

-NCOA1chr2

24949456

+
5CDS-intronENST00000344493ENST00000395856PAX3chr2

223085940

-NCOA1chr2

24949456

+
In-frameENST00000350526ENST00000406961PAX3chr2

223085940

-NCOA1chr2

24949456

+
5CDS-intronENST00000350526ENST00000469850PAX3chr2

223085940

-NCOA1chr2

24949456

+
5CDS-intronENST00000350526ENST00000405141PAX3chr2

223085940

-NCOA1chr2

24949456

+
5CDS-intronENST00000350526ENST00000407230PAX3chr2

223085940

-NCOA1chr2

24949456

+
5CDS-intronENST00000350526ENST00000538539PAX3chr2

223085940

-NCOA1chr2

24949456

+
5CDS-intronENST00000350526ENST00000288599PAX3chr2

223085940

-NCOA1chr2

24949456

+
5CDS-intronENST00000350526ENST00000348332PAX3chr2

223085940

-NCOA1chr2

24949456

+
5CDS-intronENST00000350526ENST00000395856PAX3chr2

223085940

-NCOA1chr2

24949456

+
In-frameENST00000336840ENST00000406961PAX3chr2

223085940

-NCOA1chr2

24949456

+
5CDS-intronENST00000336840ENST00000469850PAX3chr2

223085940

-NCOA1chr2

24949456

+
5CDS-intronENST00000336840ENST00000405141PAX3chr2

223085940

-NCOA1chr2

24949456

+
5CDS-intronENST00000336840ENST00000407230PAX3chr2

223085940

-NCOA1chr2

24949456

+
5CDS-intronENST00000336840ENST00000538539PAX3chr2

223085940

-NCOA1chr2

24949456

+
5CDS-intronENST00000336840ENST00000288599PAX3chr2

223085940

-NCOA1chr2

24949456

+
5CDS-intronENST00000336840ENST00000348332PAX3chr2

223085940

-NCOA1chr2

24949456

+
5CDS-intronENST00000336840ENST00000395856PAX3chr2

223085940

-NCOA1chr2

24949456

+
In-frameENST00000392070ENST00000406961PAX3chr2

223085940

-NCOA1chr2

24949456

+
5CDS-intronENST00000392070ENST00000469850PAX3chr2

223085940

-NCOA1chr2

24949456

+
5CDS-intronENST00000392070ENST00000405141PAX3chr2

223085940

-NCOA1chr2

24949456

+
5CDS-intronENST00000392070ENST00000407230PAX3chr2

223085940

-NCOA1chr2

24949456

+
5CDS-intronENST00000392070ENST00000538539PAX3chr2

223085940

-NCOA1chr2

24949456

+
5CDS-intronENST00000392070ENST00000288599PAX3chr2

223085940

-NCOA1chr2

24949456

+
5CDS-intronENST00000392070ENST00000348332PAX3chr2

223085940

-NCOA1chr2

24949456

+
5CDS-intronENST00000392070ENST00000395856PAX3chr2

223085940

-NCOA1chr2

24949456

+
In-frameENST00000409551ENST00000406961PAX3chr2

223085940

-NCOA1chr2

24949456

+
5CDS-intronENST00000409551ENST00000469850PAX3chr2

223085940

-NCOA1chr2

24949456

+
5CDS-intronENST00000409551ENST00000405141PAX3chr2

223085940

-NCOA1chr2

24949456

+
5CDS-intronENST00000409551ENST00000407230PAX3chr2

223085940

-NCOA1chr2

24949456

+
5CDS-intronENST00000409551ENST00000538539PAX3chr2

223085940

-NCOA1chr2

24949456

+
5CDS-intronENST00000409551ENST00000288599PAX3chr2

223085940

-NCOA1chr2

24949456

+
5CDS-intronENST00000409551ENST00000348332PAX3chr2

223085940

-NCOA1chr2

24949456

+
5CDS-intronENST00000409551ENST00000395856PAX3chr2

223085940

-NCOA1chr2

24949456

+
5UTR-3CDSENST00000464706ENST00000406961PAX3chr2

223085940

-NCOA1chr2

24949456

+
5UTR-intronENST00000464706ENST00000469850PAX3chr2

223085940

-NCOA1chr2

24949456

+
5UTR-intronENST00000464706ENST00000405141PAX3chr2

223085940

-NCOA1chr2

24949456

+
5UTR-intronENST00000464706ENST00000407230PAX3chr2

223085940

-NCOA1chr2

24949456

+
5UTR-intronENST00000464706ENST00000538539PAX3chr2

223085940

-NCOA1chr2

24949456

+
5UTR-intronENST00000464706ENST00000288599PAX3chr2

223085940

-NCOA1chr2

24949456

+
5UTR-intronENST00000464706ENST00000348332PAX3chr2

223085940

-NCOA1chr2

24949456

+
5UTR-intronENST00000464706ENST00000395856PAX3chr2

223085940

-NCOA1chr2

24949456

+
intron-3CDSENST00000409828ENST00000406961PAX3chr2

223085940

-NCOA1chr2

24949456

+
intron-intronENST00000409828ENST00000469850PAX3chr2

223085940

-NCOA1chr2

24949456

+
intron-intronENST00000409828ENST00000405141PAX3chr2

223085940

-NCOA1chr2

24949456

+
intron-intronENST00000409828ENST00000407230PAX3chr2

223085940

-NCOA1chr2

24949456

+
intron-intronENST00000409828ENST00000538539PAX3chr2

223085940

-NCOA1chr2

24949456

+
intron-intronENST00000409828ENST00000288599PAX3chr2

223085940

-NCOA1chr2

24949456

+
intron-intronENST00000409828ENST00000348332PAX3chr2

223085940

-NCOA1chr2

24949456

+
intron-intronENST00000409828ENST00000395856PAX3chr2

223085940

-NCOA1chr2

24949456

+
intron-3CDSENST00000258387ENST00000406961PAX3chr2

223085940

-NCOA1chr2

24949456

+
intron-intronENST00000258387ENST00000469850PAX3chr2

223085940

-NCOA1chr2

24949456

+
intron-intronENST00000258387ENST00000405141PAX3chr2

223085940

-NCOA1chr2

24949456

+
intron-intronENST00000258387ENST00000407230PAX3chr2

223085940

-NCOA1chr2

24949456

+
intron-intronENST00000258387ENST00000538539PAX3chr2

223085940

-NCOA1chr2

24949456

+
intron-intronENST00000258387ENST00000288599PAX3chr2

223085940

-NCOA1chr2

24949456

+
intron-intronENST00000258387ENST00000348332PAX3chr2

223085940

-NCOA1chr2

24949456

+
intron-intronENST00000258387ENST00000395856PAX3chr2

223085940

-NCOA1chr2

24949456

+

Top

FusionProtFeatures for PAX3_NCOA1


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
PAX3

P23760

NCOA1

Q15788


check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePAX3chr2:223085940chr2:24949456ENST00000336840-69219_278319408DNA bindingHomeobox
HgenePAX3chr2:223085940chr2:24949456ENST00000344493-68219_278319404DNA bindingHomeobox
HgenePAX3chr2:223085940chr2:24949456ENST00000350526-68219_278319480DNA bindingHomeobox
HgenePAX3chr2:223085940chr2:24949456ENST00000392069-610219_278319506DNA bindingHomeobox
HgenePAX3chr2:223085940chr2:24949456ENST00000392070-69219_278319485DNA bindingHomeobox
HgenePAX3chr2:223085940chr2:24949456ENST00000409551-69219_278318484DNA bindingHomeobox
HgenePAX3chr2:223085940chr2:24949456ENST00000336840-6934_161319408DomainPaired
HgenePAX3chr2:223085940chr2:24949456ENST00000344493-6834_161319404DomainPaired
HgenePAX3chr2:223085940chr2:24949456ENST00000350526-6834_161319480DomainPaired
HgenePAX3chr2:223085940chr2:24949456ENST00000392069-61034_161319506DomainPaired
HgenePAX3chr2:223085940chr2:24949456ENST00000392070-6934_161319485DomainPaired
HgenePAX3chr2:223085940chr2:24949456ENST00000409551-6934_161318484DomainPaired
TgeneNCOA1chr2:223085940chr2:24949456ENST00000288599+11221053_11388662199Compositional biasNote=Gln-rich
TgeneNCOA1chr2:223085940chr2:24949456ENST00000348332+11211053_11388661442Compositional biasNote=Gln-rich
TgeneNCOA1chr2:223085940chr2:24949456ENST00000395856+11211053_11388661441Compositional biasNote=Gln-rich
TgeneNCOA1chr2:223085940chr2:24949456ENST00000405141+14251053_11388662183Compositional biasNote=Gln-rich
TgeneNCOA1chr2:223085940chr2:24949456ENST00000406961+13231053_11388661442Compositional biasNote=Gln-rich
TgeneNCOA1chr2:223085940chr2:24949456ENST00000538539+12231053_11388661422Compositional biasNote=Gln-rich
TgeneNCOA1chr2:223085940chr2:24949456ENST00000288599+11221435_14398662199MotifNote=LXXLL motif 7
TgeneNCOA1chr2:223085940chr2:24949456ENST00000288599+1122913_9178662199MotifNote=LXXLL motif 6
TgeneNCOA1chr2:223085940chr2:24949456ENST00000348332+11211435_14398661442MotifNote=LXXLL motif 7
TgeneNCOA1chr2:223085940chr2:24949456ENST00000348332+1121913_9178661442MotifNote=LXXLL motif 6
TgeneNCOA1chr2:223085940chr2:24949456ENST00000395856+11211435_14398661441MotifNote=LXXLL motif 7
TgeneNCOA1chr2:223085940chr2:24949456ENST00000395856+1121913_9178661441MotifNote=LXXLL motif 6
TgeneNCOA1chr2:223085940chr2:24949456ENST00000405141+14251435_14398662183MotifNote=LXXLL motif 7
TgeneNCOA1chr2:223085940chr2:24949456ENST00000405141+1425913_9178662183MotifNote=LXXLL motif 6
TgeneNCOA1chr2:223085940chr2:24949456ENST00000406961+13231435_14398661442MotifNote=LXXLL motif 7
TgeneNCOA1chr2:223085940chr2:24949456ENST00000406961+1323913_9178661442MotifNote=LXXLL motif 6
TgeneNCOA1chr2:223085940chr2:24949456ENST00000538539+12231435_14398661422MotifNote=LXXLL motif 7
TgeneNCOA1chr2:223085940chr2:24949456ENST00000538539+1223913_9178661422MotifNote=LXXLL motif 6

- In-frame and not-retained protein feature among the 13 regional features.
>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePAX3chr2:223085940chr2:24949456ENST00000258387-15219_278-84207DNA bindingHomeobox
HgenePAX3chr2:223085940chr2:24949456ENST00000409828-14219_278-44216DNA bindingHomeobox
HgenePAX3chr2:223085940chr2:24949456ENST00000258387-1534_161-84207DomainPaired
HgenePAX3chr2:223085940chr2:24949456ENST00000409828-1434_161-44216DomainPaired
TgeneNCOA1chr2:223085940chr2:24949456ENST00000288599+1122389_6828662199Compositional biasNote=Ser-rich
TgeneNCOA1chr2:223085940chr2:24949456ENST00000348332+1121389_6828661442Compositional biasNote=Ser-rich
TgeneNCOA1chr2:223085940chr2:24949456ENST00000395856+1121389_6828661441Compositional biasNote=Ser-rich
TgeneNCOA1chr2:223085940chr2:24949456ENST00000405141+1425389_6828662183Compositional biasNote=Ser-rich
TgeneNCOA1chr2:223085940chr2:24949456ENST00000406961+1323389_6828661442Compositional biasNote=Ser-rich
TgeneNCOA1chr2:223085940chr2:24949456ENST00000538539+1223389_6828661422Compositional biasNote=Ser-rich
TgeneNCOA1chr2:223085940chr2:24949456ENST00000288599+1122109_1808662199DomainPAS
TgeneNCOA1chr2:223085940chr2:24949456ENST00000288599+112223_808662199DomainbHLH
TgeneNCOA1chr2:223085940chr2:24949456ENST00000348332+1121109_1808661442DomainPAS
TgeneNCOA1chr2:223085940chr2:24949456ENST00000348332+112123_808661442DomainbHLH
TgeneNCOA1chr2:223085940chr2:24949456ENST00000395856+1121109_1808661441DomainPAS
TgeneNCOA1chr2:223085940chr2:24949456ENST00000395856+112123_808661441DomainbHLH
TgeneNCOA1chr2:223085940chr2:24949456ENST00000405141+1425109_1808662183DomainPAS
TgeneNCOA1chr2:223085940chr2:24949456ENST00000405141+142523_808662183DomainbHLH
TgeneNCOA1chr2:223085940chr2:24949456ENST00000406961+1323109_1808661442DomainPAS
TgeneNCOA1chr2:223085940chr2:24949456ENST00000406961+132323_808661442DomainbHLH
TgeneNCOA1chr2:223085940chr2:24949456ENST00000538539+1223109_1808661422DomainPAS
TgeneNCOA1chr2:223085940chr2:24949456ENST00000538539+122323_808661422DomainbHLH
TgeneNCOA1chr2:223085940chr2:24949456ENST00000288599+1122112_1168662199MotifNote=LXXLL motif 2
TgeneNCOA1chr2:223085940chr2:24949456ENST00000288599+112246_508662199MotifNote=LXXLL motif 1
TgeneNCOA1chr2:223085940chr2:24949456ENST00000288599+1122633_6378662199MotifNote=LXXLL motif 3
TgeneNCOA1chr2:223085940chr2:24949456ENST00000288599+1122690_6948662199MotifNote=LXXLL motif 4
TgeneNCOA1chr2:223085940chr2:24949456ENST00000288599+1122749_7538662199MotifNote=LXXLL motif 5
TgeneNCOA1chr2:223085940chr2:24949456ENST00000348332+1121112_1168661442MotifNote=LXXLL motif 2
TgeneNCOA1chr2:223085940chr2:24949456ENST00000348332+112146_508661442MotifNote=LXXLL motif 1
TgeneNCOA1chr2:223085940chr2:24949456ENST00000348332+1121633_6378661442MotifNote=LXXLL motif 3
TgeneNCOA1chr2:223085940chr2:24949456ENST00000348332+1121690_6948661442MotifNote=LXXLL motif 4
TgeneNCOA1chr2:223085940chr2:24949456ENST00000348332+1121749_7538661442MotifNote=LXXLL motif 5
TgeneNCOA1chr2:223085940chr2:24949456ENST00000395856+1121112_1168661441MotifNote=LXXLL motif 2
TgeneNCOA1chr2:223085940chr2:24949456ENST00000395856+112146_508661441MotifNote=LXXLL motif 1
TgeneNCOA1chr2:223085940chr2:24949456ENST00000395856+1121633_6378661441MotifNote=LXXLL motif 3
TgeneNCOA1chr2:223085940chr2:24949456ENST00000395856+1121690_6948661441MotifNote=LXXLL motif 4
TgeneNCOA1chr2:223085940chr2:24949456ENST00000395856+1121749_7538661441MotifNote=LXXLL motif 5
TgeneNCOA1chr2:223085940chr2:24949456ENST00000405141+1425112_1168662183MotifNote=LXXLL motif 2
TgeneNCOA1chr2:223085940chr2:24949456ENST00000405141+142546_508662183MotifNote=LXXLL motif 1
TgeneNCOA1chr2:223085940chr2:24949456ENST00000405141+1425633_6378662183MotifNote=LXXLL motif 3
TgeneNCOA1chr2:223085940chr2:24949456ENST00000405141+1425690_6948662183MotifNote=LXXLL motif 4
TgeneNCOA1chr2:223085940chr2:24949456ENST00000405141+1425749_7538662183MotifNote=LXXLL motif 5
TgeneNCOA1chr2:223085940chr2:24949456ENST00000406961+1323112_1168661442MotifNote=LXXLL motif 2
TgeneNCOA1chr2:223085940chr2:24949456ENST00000406961+132346_508661442MotifNote=LXXLL motif 1
TgeneNCOA1chr2:223085940chr2:24949456ENST00000406961+1323633_6378661442MotifNote=LXXLL motif 3
TgeneNCOA1chr2:223085940chr2:24949456ENST00000406961+1323690_6948661442MotifNote=LXXLL motif 4
TgeneNCOA1chr2:223085940chr2:24949456ENST00000406961+1323749_7538661442MotifNote=LXXLL motif 5
TgeneNCOA1chr2:223085940chr2:24949456ENST00000538539+1223112_1168661422MotifNote=LXXLL motif 2
TgeneNCOA1chr2:223085940chr2:24949456ENST00000538539+122346_508661422MotifNote=LXXLL motif 1
TgeneNCOA1chr2:223085940chr2:24949456ENST00000538539+1223633_6378661422MotifNote=LXXLL motif 3
TgeneNCOA1chr2:223085940chr2:24949456ENST00000538539+1223690_6948661422MotifNote=LXXLL motif 4
TgeneNCOA1chr2:223085940chr2:24949456ENST00000538539+1223749_7538661422MotifNote=LXXLL motif 5


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FusionGeneSequence for PAX3_NCOA1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.

* Fusion transcript sequences (only coding sequence (CDS) region).

* Fusion transcript sequences (Full-length transcript).
>In-frame_PAX3_ENST00000392069_chr2_223085940_-_NCOA1_ENST00000406961_chr2_24949456_+_5362nt
AGGAGGAGACTCAGGCAGGCCGCGCTCCAGCCTCACCAGGCTCCCCGGCTCGCCGTGGCTCTCTGAGCCCCCTTTTCAGGGACCCCAGTC
GCTGGAACATTTGCCCAGACTCGTACCAAACTTTTCCGCCCTGGGCTCGGGATCCTGGACTCCGGGGCCTCCCCGTCCTCCCCTTTCCCG
GGTTCCAGCTCCGGCCTCTGGACTAGGAACCGACAGCCCCCCTCCCCGCGTCCCTCCCTCTCTCTCCAGCCGTTTTGGGGAGGGGCTCTC
CACGCTCCGGATAGTTCCCGAGGGTCATCCGCGCCGCACTCGCCTTTCCGTTTCGCCTTCACCTGGATATAATTTCCGAGCGAAGCTGCC
CCCAGGATGACCACGCTGGCCGGCGCTGTGCCCAGGATGATGCGGCCGGGCCCGGGGCAGAACTACCCGCGTAGCGGGTTCCCGCTGGAA
GTGTCCACTCCCCTCGGCCAGGGCCGCGTCAACCAGCTCGGCGGTGTTTTTATCAACGGCAGGCCGCTGCCCAACCACATCCGCCACAAG
ATCGTGGAGATGGCCCACCACGGCATCCGGCCCTGCGTCATCTCGCGCCAGCTGCGCGTGTCCCACGGCTGCGTCTCCAAGATCCTGTGC
AGGTACCAGGAGACTGGCTCCATACGTCCTGGTGCCATCGGCGGCAGCAAGCCCAAGCAGGTGACAACGCCTGACGTGGAGAAGAAAATT
GAGGAATACAAAAGAGAGAACCCGGGCATGTTCAGCTGGGAAATCCGAGACAAATTACTCAAGGACGCGGTCTGTGATCGAAACACCGTG
CCGTCAGTGAGTTCCATCAGCCGCATCCTGAGAAGTAAATTCGGGAAAGGTGAAGAGGAGGAGGCCGACTTGGAGAGGAAGGAGGCAGAG
GAAAGCGAGAAGAAGGCCAAACACAGCATCGACGGCATCCTGAGCGAGCGAGCCTCAGCACCCCAATCAGATGAAGGCTCTGATATTGAC
TCTGAACCAGATTTACCACTAAAGAGGAAACAGCGCAGAAGCCGAACCACCTTCACAGCAGAACAGCTGGAGGAACTGGAGCGTGCTTTT
GAGAGAACTCATTACCCTGACATTTATACTAGGGAGGAACTGGCCCAGAGGGCGAAGCTCACCGAGGCCCGAGTACAGGTCTGGTTTAGC
AACCGCCGTGCAAGATGGAGGAAGCAAGCTGGGGCCAATCAACTGATGGCTTTCAACCATCTCATTCCCGGGGGGTTCCCTCCCACTGCC
ATGCCGACCTTGCCAACGTACCAGCTGTCGGAGACCTCTTACCAGCCCACATCTATTCCACAAGGATTACCTGAGCTGGAATTGGAAGCA
ATTGATAACCAATTTGGACAACCAGGAACAGGCGATCAGATTCCATGGACAAATAATACAGTGACAGCTATAAATCAGAGTAAATCAGAA
GACCAGTGTATTAGCTCACAATTAGATGAGCTTCTCTGTCCACCCACAACAGTAGAAGGGAGAAATGATGAGAAGGCTCTTCTTGAACAG
CTGGTATCCTTCCTTAGTGGCAAAGATGAAACTGAGCTAGCTGAACTAGACAGAGCTCTGGGAATTGACAAACTTGTTCAGGGGGGTGGA
TTAGATGTATTATCAGAGAGATTTCCACCACAACAAGCAACGCCACCTTTGATCATGGAAGAAAGACCCAACCTTTATTCCCAGCCTTAC
TCTTCTCCTTCTCCTACTGCCAATCTCCCTAGCCCTTTCCAAGGCATGGTCAGGCAAAAACCTTCACTGGGGACGATGCCTGTTCAAGTA
ACACCTCCCCGAGGTGCTTTTTCACCTGGCATGGGCATGCAGCCCAGGCAAACTCTAAACAGACCTCCGGCTGCACCTAACCAGCTTCGA
CTTCAACTACAGCAGCGATTACAGGGACAACAGCAGTTGATACACCAAAATCGGCAAGCTATCTTAAACCAGTTTGCAGCAACTGCTCCT
GTTGGCATCAATATGAGATCAGGCATGCAACAGCAAATTACACCTCAGCCACCCCTGAATGCTCAAATGTTGGCACAACGTCAGCGGGAA
CTGTACAGTCAACAGCACCGACAGAGGCAGCTAATACAGCAGCAAAGAGCCATGCTTATGAGGCAGCAAAGCTTTGGGAACAACCTCCCT
CCCTCATCTGGACTACCAGTTCAAATGGGGAACCCCCGTCTTCCTCAGGGTGCTCCACAGCAATTCCCCTATCCACCAAACTATGGTACA
AATCCAGGAACCCCACCTGCTTCTACCAGCCCGTTTTCACAACTAGCAGCAAATCCTGAAGCATCCTTGGCCAACCGCAACAGCATGGTG
AGCAGAGGCATGACAGGAAACATAGGAGGACAGTTTGGCACTGGAATCAATCCTCAGATGCAGCAGAATGTCTTCCAGTATCCAGGAGCA
GGAATGGTTCCCCAAGGTGAGGCCAACTTTGCTCCATCTCTAAGCCCTGGGAGCTCCATGGTGCCGATGCCAATCCCTCCTCCTCAGAGT
TCTCTTCTCCAGCAAACTCCACCTGCCTCCGGGTATCAGTCACCAGACATGAAGGCCTGGCAGCAAGGAGCGATAGGAAACAACAATGTG
TTCAGTCAAGCTGTCCAGAACCAGCCCACGCCTGCACAGCCAGGAGTATACAACAACATGAGCATCACCGTTTCCATGGCAGGTGGAAAT
ACGAATGTTCAGAACATGAACCCAATGATGGCCCAGATGCAGATGAGCTCTTTGCAGATGCCAGGAATGAACACTGTGTGCCCTGAGCAG
ATAAATGATCCCGCACTGAGACACACAGGCCTCTACTGCAACCAGCTCTCATCCACTGACCTTCTCAAAACAGAAGCAGATGGAACCCAG
CAGGTGCAACAGGTTCAGGTGTTTGCTGACGTCCAGTGTACAGTGAATCTGGTAGGCGGGGACCCTTACCTGAACCAGCCTGGTCCACTG
GGAACTCAAAAGCCCACGTCAGGACCACAGACCCCCCAGGCCCAGCAGAAGAGCCTCCTTCAGCAGCTACTGACTGAATAACCACTTTTA
AAGGAATGTGAAATTTAAATAATAGACATACAGAGATATACAAATATATTATATATTTTTCTGAGATTTTTGATATCTCAATCTGCAGCC
ATTCTTCAGGTCGTAGCATTTGGAGCAAAAAAAAAAAAAAAAAAAAAAAAAGGAGTTTGCTTTTGTCGGGAGATTGAAAGATGTTTTTGT
TTCTTTCTTTGTAAAGGCCTTGGATATTGAAAAAATACCAAGGCAGAACAGTTGGACAATCTATTTCTTGAGCCAAATTTAATTATTCTT
ATTTTTGTAATCAGTCATTGGCTTCTTATCTGGATGAAGGCTTTTGGAGGAGAACCAAAACGACAAGTTCCAAGAAGAAGATGAAGCTCC
GCCTCCGCCGCTTAGTCCCAACCCTGCCCAGGAAGAAGGGCCCGTGGGGCTTTGCCTGTGCCCGTCCACCAAAGGCTGTCATGTGTCTCG
AAATCAGCAGCCCTCCCCATCCCAATCCCAGGCAGCTTGTGTGTACAATCAGCTTCTCTAGCAACTCTGTATCTGTTGGCTTCAAGAGAA
TATTTTGCCTCCACATATGTACCCCTTCTCCTTTTTTTAAAGATGGATTTAAACCAAGATGCCTCCAGGAAAGAGGACGAAATGAGTATA
TTCACAGAGGAATCCAAAAAATACAGTTTGGGGGAAAATGCAATAATTTTTGATGAGATGGGTGAAGGACAAGAAGTGAGTTGTGTCAAT
TATTGTAGATACAATTTTCTGATTAAATCTGGAAAAATAAAAGGCAGCCTGTTTTTTCTGCTTTTATTGTATTAACAGCTGAGGTAGCTA
AAGTTATTTAAAATAAAATTAAATTTATGATCCAAGTAGCTTATTTTTCCCTTTAAATCTCATTGTAAATATATTTGATTTCTTGTAGAA
ATTGATTTCCTTCTGTTTAATTTTATGCTTTTATTATACTCTTGATTTTTCTAAATTTGTGTGTGAAATATAACATTGATTGAATTGCAG
TTACATTTGGTTAGTAATATTTCATTATTTTAATAACTGTGATGTCATGTATGGATTTACTTTGGGGTTCAAATCAAAATGTCACTGCCA
GAAAGAGCTGTTCCAGCTGATCTAGAGCATACTGCCCTAGAGTGTCCCTGGGATCATCTGAACAGAAGTGCACAGGCTACTTGTACAGAG
AAAAAATTAATACTCAAAGGAAATCTTCATTTTTTAGATTGACTTTGGGAATTTGAATTTTCATCAGTGCAAATATAAATTTCTCTATCC
TGCTCTGAGGCTAATTGGTACCATATTTTCCCTTTGTGTCTTGTGACTCTGCCACATCCCATCTCATCCTGGCCTCTGAGTCAAGAACCC
AGTGAACTGACTTTCTAGTTCTAGAAGTTCCGCTGCAAGGCCAGGAAAGCTTGAGAAAGGTATTGTGGAAGAAGCAAAGGTAGACCCCCA
TCACTCACCTTTGTCTGCATCCCTGGGCCTGTGAATGATGACAGCACCTGACATTCTGCACCAGCTACCTCTGCCTCCATGGCAGAGAAA
AGGCCATAAGAACAGTGGAAGAGGAGCATGGACTCAGACTTCAAGGAAGAAGCCATTTCCCCAGGTCCTTCCTTCTGCATCTCACCACCC
CTAGTTACAAATAACTCCATTGAACAGCATCTATTCAGAAACTATGCCGAATAAAAAGATTGGTGGAAGGGCTCATGTGGTTAGCAACTA
TGAAACAGAAATAGGACACTCAGTTACAAACATTATCTCCTTTAGTTTTTCAGAAAATGCATCCCTGATTTCATTCATTTCCAGCTTGAA
AGCCAGCCATATTACTCTAGTCCCTACCAAACTGCTCTAGAAGGTCATTTCCATTTTGTTTGTGATATTTAGACGCGCAGACTTCAGGAA
GTTCACCTTTAACTTCAGCATTCCAGATGAAGTTTCCTGACTCAGTGCTTTTGCATAAGGAACTAGAAAAAAAAAGTAAGGAAAATTGGA
GATGCTAACATCCTCCCCCATCCCAACTGCACCTTAAAATATGCATGTCACCTTCAAGGTTTTATAATTGCACTGTTTGTTTTATGTATG
TACAGATTAAAATTATTGCTACATTTGAGGAAAATAAAATTGCTTGCTTCTATGTAATTCCTGTCATTCCACAGGAAATTCACTTTTCCA
GCTACTGAATAGAATTTGTTTAACAACCTCATGGGTTGCCTCTTCATTTACAGGGAAGAAATGAAATGTACATCTGCAGAAATTGCCAAA

>In-frame_PAX3_ENST00000344493_chr2_223085940_-_NCOA1_ENST00000406961_chr2_24949456_+_5377nt
ACTCGGTGTCACCACAGGAGGAGACTCAGGCAGGCCGCGCTCCAGCCTCACCAGGCTCCCCGGCTCGCCGTGGCTCTCTGAGCCCCCTTT
TCAGGGACCCCAGTCGCTGGAACATTTGCCCAGACTCGTACCAAACTTTTCCGCCCTGGGCTCGGGATCCTGGACTCCGGGGCCTCCCCG
TCCTCCCCTTTCCCGGGTTCCAGCTCCGGCCTCTGGACTAGGAACCGACAGCCCCCCTCCCCGCGTCCCTCCCTCTCTCTCCAGCCGTTT
TGGGGAGGGGCTCTCCACGCTCCGGATAGTTCCCGAGGGTCATCCGCGCCGCACTCGCCTTTCCGTTTCGCCTTCACCTGGATATAATTT
CCGAGCGAAGCTGCCCCCAGGATGACCACGCTGGCCGGCGCTGTGCCCAGGATGATGCGGCCGGGCCCGGGGCAGAACTACCCGCGTAGC
GGGTTCCCGCTGGAAGTGTCCACTCCCCTCGGCCAGGGCCGCGTCAACCAGCTCGGCGGTGTTTTTATCAACGGCAGGCCGCTGCCCAAC
CACATCCGCCACAAGATCGTGGAGATGGCCCACCACGGCATCCGGCCCTGCGTCATCTCGCGCCAGCTGCGCGTGTCCCACGGCTGCGTC
TCCAAGATCCTGTGCAGGTACCAGGAGACTGGCTCCATACGTCCTGGTGCCATCGGCGGCAGCAAGCCCAAGCAGGTGACAACGCCTGAC
GTGGAGAAGAAAATTGAGGAATACAAAAGAGAGAACCCGGGCATGTTCAGCTGGGAAATCCGAGACAAATTACTCAAGGACGCGGTCTGT
GATCGAAACACCGTGCCGTCAGTGAGTTCCATCAGCCGCATCCTGAGAAGTAAATTCGGGAAAGGTGAAGAGGAGGAGGCCGACTTGGAG
AGGAAGGAGGCAGAGGAAAGCGAGAAGAAGGCCAAACACAGCATCGACGGCATCCTGAGCGAGCGAGCCTCAGCACCCCAATCAGATGAA
GGCTCTGATATTGACTCTGAACCAGATTTACCACTAAAGAGGAAACAGCGCAGAAGCCGAACCACCTTCACAGCAGAACAGCTGGAGGAA
CTGGAGCGTGCTTTTGAGAGAACTCATTACCCTGACATTTATACTAGGGAGGAACTGGCCCAGAGGGCGAAGCTCACCGAGGCCCGAGTA
CAGGTCTGGTTTAGCAACCGCCGTGCAAGATGGAGGAAGCAAGCTGGGGCCAATCAACTGATGGCTTTCAACCATCTCATTCCCGGGGGG
TTCCCTCCCACTGCCATGCCGACCTTGCCAACGTACCAGCTGTCGGAGACCTCTTACCAGCCCACATCTATTCCACAAGGATTACCTGAG
CTGGAATTGGAAGCAATTGATAACCAATTTGGACAACCAGGAACAGGCGATCAGATTCCATGGACAAATAATACAGTGACAGCTATAAAT
CAGAGTAAATCAGAAGACCAGTGTATTAGCTCACAATTAGATGAGCTTCTCTGTCCACCCACAACAGTAGAAGGGAGAAATGATGAGAAG
GCTCTTCTTGAACAGCTGGTATCCTTCCTTAGTGGCAAAGATGAAACTGAGCTAGCTGAACTAGACAGAGCTCTGGGAATTGACAAACTT
GTTCAGGGGGGTGGATTAGATGTATTATCAGAGAGATTTCCACCACAACAAGCAACGCCACCTTTGATCATGGAAGAAAGACCCAACCTT
TATTCCCAGCCTTACTCTTCTCCTTCTCCTACTGCCAATCTCCCTAGCCCTTTCCAAGGCATGGTCAGGCAAAAACCTTCACTGGGGACG
ATGCCTGTTCAAGTAACACCTCCCCGAGGTGCTTTTTCACCTGGCATGGGCATGCAGCCCAGGCAAACTCTAAACAGACCTCCGGCTGCA
CCTAACCAGCTTCGACTTCAACTACAGCAGCGATTACAGGGACAACAGCAGTTGATACACCAAAATCGGCAAGCTATCTTAAACCAGTTT
GCAGCAACTGCTCCTGTTGGCATCAATATGAGATCAGGCATGCAACAGCAAATTACACCTCAGCCACCCCTGAATGCTCAAATGTTGGCA
CAACGTCAGCGGGAACTGTACAGTCAACAGCACCGACAGAGGCAGCTAATACAGCAGCAAAGAGCCATGCTTATGAGGCAGCAAAGCTTT
GGGAACAACCTCCCTCCCTCATCTGGACTACCAGTTCAAATGGGGAACCCCCGTCTTCCTCAGGGTGCTCCACAGCAATTCCCCTATCCA
CCAAACTATGGTACAAATCCAGGAACCCCACCTGCTTCTACCAGCCCGTTTTCACAACTAGCAGCAAATCCTGAAGCATCCTTGGCCAAC
CGCAACAGCATGGTGAGCAGAGGCATGACAGGAAACATAGGAGGACAGTTTGGCACTGGAATCAATCCTCAGATGCAGCAGAATGTCTTC
CAGTATCCAGGAGCAGGAATGGTTCCCCAAGGTGAGGCCAACTTTGCTCCATCTCTAAGCCCTGGGAGCTCCATGGTGCCGATGCCAATC
CCTCCTCCTCAGAGTTCTCTTCTCCAGCAAACTCCACCTGCCTCCGGGTATCAGTCACCAGACATGAAGGCCTGGCAGCAAGGAGCGATA
GGAAACAACAATGTGTTCAGTCAAGCTGTCCAGAACCAGCCCACGCCTGCACAGCCAGGAGTATACAACAACATGAGCATCACCGTTTCC
ATGGCAGGTGGAAATACGAATGTTCAGAACATGAACCCAATGATGGCCCAGATGCAGATGAGCTCTTTGCAGATGCCAGGAATGAACACT
GTGTGCCCTGAGCAGATAAATGATCCCGCACTGAGACACACAGGCCTCTACTGCAACCAGCTCTCATCCACTGACCTTCTCAAAACAGAA
GCAGATGGAACCCAGCAGGTGCAACAGGTTCAGGTGTTTGCTGACGTCCAGTGTACAGTGAATCTGGTAGGCGGGGACCCTTACCTGAAC
CAGCCTGGTCCACTGGGAACTCAAAAGCCCACGTCAGGACCACAGACCCCCCAGGCCCAGCAGAAGAGCCTCCTTCAGCAGCTACTGACT
GAATAACCACTTTTAAAGGAATGTGAAATTTAAATAATAGACATACAGAGATATACAAATATATTATATATTTTTCTGAGATTTTTGATA
TCTCAATCTGCAGCCATTCTTCAGGTCGTAGCATTTGGAGCAAAAAAAAAAAAAAAAAAAAAAAAAGGAGTTTGCTTTTGTCGGGAGATT
GAAAGATGTTTTTGTTTCTTTCTTTGTAAAGGCCTTGGATATTGAAAAAATACCAAGGCAGAACAGTTGGACAATCTATTTCTTGAGCCA
AATTTAATTATTCTTATTTTTGTAATCAGTCATTGGCTTCTTATCTGGATGAAGGCTTTTGGAGGAGAACCAAAACGACAAGTTCCAAGA
AGAAGATGAAGCTCCGCCTCCGCCGCTTAGTCCCAACCCTGCCCAGGAAGAAGGGCCCGTGGGGCTTTGCCTGTGCCCGTCCACCAAAGG
CTGTCATGTGTCTCGAAATCAGCAGCCCTCCCCATCCCAATCCCAGGCAGCTTGTGTGTACAATCAGCTTCTCTAGCAACTCTGTATCTG
TTGGCTTCAAGAGAATATTTTGCCTCCACATATGTACCCCTTCTCCTTTTTTTAAAGATGGATTTAAACCAAGATGCCTCCAGGAAAGAG
GACGAAATGAGTATATTCACAGAGGAATCCAAAAAATACAGTTTGGGGGAAAATGCAATAATTTTTGATGAGATGGGTGAAGGACAAGAA
GTGAGTTGTGTCAATTATTGTAGATACAATTTTCTGATTAAATCTGGAAAAATAAAAGGCAGCCTGTTTTTTCTGCTTTTATTGTATTAA
CAGCTGAGGTAGCTAAAGTTATTTAAAATAAAATTAAATTTATGATCCAAGTAGCTTATTTTTCCCTTTAAATCTCATTGTAAATATATT
TGATTTCTTGTAGAAATTGATTTCCTTCTGTTTAATTTTATGCTTTTATTATACTCTTGATTTTTCTAAATTTGTGTGTGAAATATAACA
TTGATTGAATTGCAGTTACATTTGGTTAGTAATATTTCATTATTTTAATAACTGTGATGTCATGTATGGATTTACTTTGGGGTTCAAATC
AAAATGTCACTGCCAGAAAGAGCTGTTCCAGCTGATCTAGAGCATACTGCCCTAGAGTGTCCCTGGGATCATCTGAACAGAAGTGCACAG
GCTACTTGTACAGAGAAAAAATTAATACTCAAAGGAAATCTTCATTTTTTAGATTGACTTTGGGAATTTGAATTTTCATCAGTGCAAATA
TAAATTTCTCTATCCTGCTCTGAGGCTAATTGGTACCATATTTTCCCTTTGTGTCTTGTGACTCTGCCACATCCCATCTCATCCTGGCCT
CTGAGTCAAGAACCCAGTGAACTGACTTTCTAGTTCTAGAAGTTCCGCTGCAAGGCCAGGAAAGCTTGAGAAAGGTATTGTGGAAGAAGC
AAAGGTAGACCCCCATCACTCACCTTTGTCTGCATCCCTGGGCCTGTGAATGATGACAGCACCTGACATTCTGCACCAGCTACCTCTGCC
TCCATGGCAGAGAAAAGGCCATAAGAACAGTGGAAGAGGAGCATGGACTCAGACTTCAAGGAAGAAGCCATTTCCCCAGGTCCTTCCTTC
TGCATCTCACCACCCCTAGTTACAAATAACTCCATTGAACAGCATCTATTCAGAAACTATGCCGAATAAAAAGATTGGTGGAAGGGCTCA
TGTGGTTAGCAACTATGAAACAGAAATAGGACACTCAGTTACAAACATTATCTCCTTTAGTTTTTCAGAAAATGCATCCCTGATTTCATT
CATTTCCAGCTTGAAAGCCAGCCATATTACTCTAGTCCCTACCAAACTGCTCTAGAAGGTCATTTCCATTTTGTTTGTGATATTTAGACG
CGCAGACTTCAGGAAGTTCACCTTTAACTTCAGCATTCCAGATGAAGTTTCCTGACTCAGTGCTTTTGCATAAGGAACTAGAAAAAAAAA
GTAAGGAAAATTGGAGATGCTAACATCCTCCCCCATCCCAACTGCACCTTAAAATATGCATGTCACCTTCAAGGTTTTATAATTGCACTG
TTTGTTTTATGTATGTACAGATTAAAATTATTGCTACATTTGAGGAAAATAAAATTGCTTGCTTCTATGTAATTCCTGTCATTCCACAGG
AAATTCACTTTTCCAGCTACTGAATAGAATTTGTTTAACAACCTCATGGGTTGCCTCTTCATTTACAGGGAAGAAATGAAATGTACATCT

>In-frame_PAX3_ENST00000350526_chr2_223085940_-_NCOA1_ENST00000406961_chr2_24949456_+_5133nt
GTCCCTCCCTCTCTCTCCAGCCGTTTTGGGGAGGGGCTCTCCACGCTCCGGATAGTTCCCGAGGGTCATCCGCGCCGCACTCGCCTTTCC
GTTTCGCCTTCACCTGGATATAATTTCCGAGCGAAGCTGCCCCCAGGATGACCACGCTGGCCGGCGCTGTGCCCAGGATGATGCGGCCGG
GCCCGGGGCAGAACTACCCGCGTAGCGGGTTCCCGCTGGAAGTGTCCACTCCCCTCGGCCAGGGCCGCGTCAACCAGCTCGGCGGTGTTT
TTATCAACGGCAGGCCGCTGCCCAACCACATCCGCCACAAGATCGTGGAGATGGCCCACCACGGCATCCGGCCCTGCGTCATCTCGCGCC
AGCTGCGCGTGTCCCACGGCTGCGTCTCCAAGATCCTGTGCAGGTACCAGGAGACTGGCTCCATACGTCCTGGTGCCATCGGCGGCAGCA
AGCCCAAGCAGGTGACAACGCCTGACGTGGAGAAGAAAATTGAGGAATACAAAAGAGAGAACCCGGGCATGTTCAGCTGGGAAATCCGAG
ACAAATTACTCAAGGACGCGGTCTGTGATCGAAACACCGTGCCGTCAGTGAGTTCCATCAGCCGCATCCTGAGAAGTAAATTCGGGAAAG
GTGAAGAGGAGGAGGCCGACTTGGAGAGGAAGGAGGCAGAGGAAAGCGAGAAGAAGGCCAAACACAGCATCGACGGCATCCTGAGCGAGC
GAGCCTCAGCACCCCAATCAGATGAAGGCTCTGATATTGACTCTGAACCAGATTTACCACTAAAGAGGAAACAGCGCAGAAGCCGAACCA
CCTTCACAGCAGAACAGCTGGAGGAACTGGAGCGTGCTTTTGAGAGAACTCATTACCCTGACATTTATACTAGGGAGGAACTGGCCCAGA
GGGCGAAGCTCACCGAGGCCCGAGTACAGGTCTGGTTTAGCAACCGCCGTGCAAGATGGAGGAAGCAAGCTGGGGCCAATCAACTGATGG
CTTTCAACCATCTCATTCCCGGGGGGTTCCCTCCCACTGCCATGCCGACCTTGCCAACGTACCAGCTGTCGGAGACCTCTTACCAGCCCA
CATCTATTCCACAAGGATTACCTGAGCTGGAATTGGAAGCAATTGATAACCAATTTGGACAACCAGGAACAGGCGATCAGATTCCATGGA
CAAATAATACAGTGACAGCTATAAATCAGAGTAAATCAGAAGACCAGTGTATTAGCTCACAATTAGATGAGCTTCTCTGTCCACCCACAA
CAGTAGAAGGGAGAAATGATGAGAAGGCTCTTCTTGAACAGCTGGTATCCTTCCTTAGTGGCAAAGATGAAACTGAGCTAGCTGAACTAG
ACAGAGCTCTGGGAATTGACAAACTTGTTCAGGGGGGTGGATTAGATGTATTATCAGAGAGATTTCCACCACAACAAGCAACGCCACCTT
TGATCATGGAAGAAAGACCCAACCTTTATTCCCAGCCTTACTCTTCTCCTTCTCCTACTGCCAATCTCCCTAGCCCTTTCCAAGGCATGG
TCAGGCAAAAACCTTCACTGGGGACGATGCCTGTTCAAGTAACACCTCCCCGAGGTGCTTTTTCACCTGGCATGGGCATGCAGCCCAGGC
AAACTCTAAACAGACCTCCGGCTGCACCTAACCAGCTTCGACTTCAACTACAGCAGCGATTACAGGGACAACAGCAGTTGATACACCAAA
ATCGGCAAGCTATCTTAAACCAGTTTGCAGCAACTGCTCCTGTTGGCATCAATATGAGATCAGGCATGCAACAGCAAATTACACCTCAGC
CACCCCTGAATGCTCAAATGTTGGCACAACGTCAGCGGGAACTGTACAGTCAACAGCACCGACAGAGGCAGCTAATACAGCAGCAAAGAG
CCATGCTTATGAGGCAGCAAAGCTTTGGGAACAACCTCCCTCCCTCATCTGGACTACCAGTTCAAATGGGGAACCCCCGTCTTCCTCAGG
GTGCTCCACAGCAATTCCCCTATCCACCAAACTATGGTACAAATCCAGGAACCCCACCTGCTTCTACCAGCCCGTTTTCACAACTAGCAG
CAAATCCTGAAGCATCCTTGGCCAACCGCAACAGCATGGTGAGCAGAGGCATGACAGGAAACATAGGAGGACAGTTTGGCACTGGAATCA
ATCCTCAGATGCAGCAGAATGTCTTCCAGTATCCAGGAGCAGGAATGGTTCCCCAAGGTGAGGCCAACTTTGCTCCATCTCTAAGCCCTG
GGAGCTCCATGGTGCCGATGCCAATCCCTCCTCCTCAGAGTTCTCTTCTCCAGCAAACTCCACCTGCCTCCGGGTATCAGTCACCAGACA
TGAAGGCCTGGCAGCAAGGAGCGATAGGAAACAACAATGTGTTCAGTCAAGCTGTCCAGAACCAGCCCACGCCTGCACAGCCAGGAGTAT
ACAACAACATGAGCATCACCGTTTCCATGGCAGGTGGAAATACGAATGTTCAGAACATGAACCCAATGATGGCCCAGATGCAGATGAGCT
CTTTGCAGATGCCAGGAATGAACACTGTGTGCCCTGAGCAGATAAATGATCCCGCACTGAGACACACAGGCCTCTACTGCAACCAGCTCT
CATCCACTGACCTTCTCAAAACAGAAGCAGATGGAACCCAGCAGGTGCAACAGGTTCAGGTGTTTGCTGACGTCCAGTGTACAGTGAATC
TGGTAGGCGGGGACCCTTACCTGAACCAGCCTGGTCCACTGGGAACTCAAAAGCCCACGTCAGGACCACAGACCCCCCAGGCCCAGCAGA
AGAGCCTCCTTCAGCAGCTACTGACTGAATAACCACTTTTAAAGGAATGTGAAATTTAAATAATAGACATACAGAGATATACAAATATAT
TATATATTTTTCTGAGATTTTTGATATCTCAATCTGCAGCCATTCTTCAGGTCGTAGCATTTGGAGCAAAAAAAAAAAAAAAAAAAAAAA
AAGGAGTTTGCTTTTGTCGGGAGATTGAAAGATGTTTTTGTTTCTTTCTTTGTAAAGGCCTTGGATATTGAAAAAATACCAAGGCAGAAC
AGTTGGACAATCTATTTCTTGAGCCAAATTTAATTATTCTTATTTTTGTAATCAGTCATTGGCTTCTTATCTGGATGAAGGCTTTTGGAG
GAGAACCAAAACGACAAGTTCCAAGAAGAAGATGAAGCTCCGCCTCCGCCGCTTAGTCCCAACCCTGCCCAGGAAGAAGGGCCCGTGGGG
CTTTGCCTGTGCCCGTCCACCAAAGGCTGTCATGTGTCTCGAAATCAGCAGCCCTCCCCATCCCAATCCCAGGCAGCTTGTGTGTACAAT
CAGCTTCTCTAGCAACTCTGTATCTGTTGGCTTCAAGAGAATATTTTGCCTCCACATATGTACCCCTTCTCCTTTTTTTAAAGATGGATT
TAAACCAAGATGCCTCCAGGAAAGAGGACGAAATGAGTATATTCACAGAGGAATCCAAAAAATACAGTTTGGGGGAAAATGCAATAATTT
TTGATGAGATGGGTGAAGGACAAGAAGTGAGTTGTGTCAATTATTGTAGATACAATTTTCTGATTAAATCTGGAAAAATAAAAGGCAGCC
TGTTTTTTCTGCTTTTATTGTATTAACAGCTGAGGTAGCTAAAGTTATTTAAAATAAAATTAAATTTATGATCCAAGTAGCTTATTTTTC
CCTTTAAATCTCATTGTAAATATATTTGATTTCTTGTAGAAATTGATTTCCTTCTGTTTAATTTTATGCTTTTATTATACTCTTGATTTT
TCTAAATTTGTGTGTGAAATATAACATTGATTGAATTGCAGTTACATTTGGTTAGTAATATTTCATTATTTTAATAACTGTGATGTCATG
TATGGATTTACTTTGGGGTTCAAATCAAAATGTCACTGCCAGAAAGAGCTGTTCCAGCTGATCTAGAGCATACTGCCCTAGAGTGTCCCT
GGGATCATCTGAACAGAAGTGCACAGGCTACTTGTACAGAGAAAAAATTAATACTCAAAGGAAATCTTCATTTTTTAGATTGACTTTGGG
AATTTGAATTTTCATCAGTGCAAATATAAATTTCTCTATCCTGCTCTGAGGCTAATTGGTACCATATTTTCCCTTTGTGTCTTGTGACTC
TGCCACATCCCATCTCATCCTGGCCTCTGAGTCAAGAACCCAGTGAACTGACTTTCTAGTTCTAGAAGTTCCGCTGCAAGGCCAGGAAAG
CTTGAGAAAGGTATTGTGGAAGAAGCAAAGGTAGACCCCCATCACTCACCTTTGTCTGCATCCCTGGGCCTGTGAATGATGACAGCACCT
GACATTCTGCACCAGCTACCTCTGCCTCCATGGCAGAGAAAAGGCCATAAGAACAGTGGAAGAGGAGCATGGACTCAGACTTCAAGGAAG
AAGCCATTTCCCCAGGTCCTTCCTTCTGCATCTCACCACCCCTAGTTACAAATAACTCCATTGAACAGCATCTATTCAGAAACTATGCCG
AATAAAAAGATTGGTGGAAGGGCTCATGTGGTTAGCAACTATGAAACAGAAATAGGACACTCAGTTACAAACATTATCTCCTTTAGTTTT
TCAGAAAATGCATCCCTGATTTCATTCATTTCCAGCTTGAAAGCCAGCCATATTACTCTAGTCCCTACCAAACTGCTCTAGAAGGTCATT
TCCATTTTGTTTGTGATATTTAGACGCGCAGACTTCAGGAAGTTCACCTTTAACTTCAGCATTCCAGATGAAGTTTCCTGACTCAGTGCT
TTTGCATAAGGAACTAGAAAAAAAAAGTAAGGAAAATTGGAGATGCTAACATCCTCCCCCATCCCAACTGCACCTTAAAATATGCATGTC
ACCTTCAAGGTTTTATAATTGCACTGTTTGTTTTATGTATGTACAGATTAAAATTATTGCTACATTTGAGGAAAATAAAATTGCTTGCTT
CTATGTAATTCCTGTCATTCCACAGGAAATTCACTTTTCCAGCTACTGAATAGAATTTGTTTAACAACCTCATGGGTTGCCTCTTCATTT
ACAGGGAAGAAATGAAATGTACATCTGCAGAAATTGCCAAAGCCCAAATTAACGAGTATTATAAAAGGATAATAAAGCATCCCTGAAGCC

>In-frame_PAX3_ENST00000336840_chr2_223085940_-_NCOA1_ENST00000406961_chr2_24949456_+_5377nt
ACTCGGTGTCACCACAGGAGGAGACTCAGGCAGGCCGCGCTCCAGCCTCACCAGGCTCCCCGGCTCGCCGTGGCTCTCTGAGCCCCCTTT
TCAGGGACCCCAGTCGCTGGAACATTTGCCCAGACTCGTACCAAACTTTTCCGCCCTGGGCTCGGGATCCTGGACTCCGGGGCCTCCCCG
TCCTCCCCTTTCCCGGGTTCCAGCTCCGGCCTCTGGACTAGGAACCGACAGCCCCCCTCCCCGCGTCCCTCCCTCTCTCTCCAGCCGTTT
TGGGGAGGGGCTCTCCACGCTCCGGATAGTTCCCGAGGGTCATCCGCGCCGCACTCGCCTTTCCGTTTCGCCTTCACCTGGATATAATTT
CCGAGCGAAGCTGCCCCCAGGATGACCACGCTGGCCGGCGCTGTGCCCAGGATGATGCGGCCGGGCCCGGGGCAGAACTACCCGCGTAGC
GGGTTCCCGCTGGAAGTGTCCACTCCCCTCGGCCAGGGCCGCGTCAACCAGCTCGGCGGTGTTTTTATCAACGGCAGGCCGCTGCCCAAC
CACATCCGCCACAAGATCGTGGAGATGGCCCACCACGGCATCCGGCCCTGCGTCATCTCGCGCCAGCTGCGCGTGTCCCACGGCTGCGTC
TCCAAGATCCTGTGCAGGTACCAGGAGACTGGCTCCATACGTCCTGGTGCCATCGGCGGCAGCAAGCCCAAGCAGGTGACAACGCCTGAC
GTGGAGAAGAAAATTGAGGAATACAAAAGAGAGAACCCGGGCATGTTCAGCTGGGAAATCCGAGACAAATTACTCAAGGACGCGGTCTGT
GATCGAAACACCGTGCCGTCAGTGAGTTCCATCAGCCGCATCCTGAGAAGTAAATTCGGGAAAGGTGAAGAGGAGGAGGCCGACTTGGAG
AGGAAGGAGGCAGAGGAAAGCGAGAAGAAGGCCAAACACAGCATCGACGGCATCCTGAGCGAGCGAGCCTCAGCACCCCAATCAGATGAA
GGCTCTGATATTGACTCTGAACCAGATTTACCACTAAAGAGGAAACAGCGCAGAAGCCGAACCACCTTCACAGCAGAACAGCTGGAGGAA
CTGGAGCGTGCTTTTGAGAGAACTCATTACCCTGACATTTATACTAGGGAGGAACTGGCCCAGAGGGCGAAGCTCACCGAGGCCCGAGTA
CAGGTCTGGTTTAGCAACCGCCGTGCAAGATGGAGGAAGCAAGCTGGGGCCAATCAACTGATGGCTTTCAACCATCTCATTCCCGGGGGG
TTCCCTCCCACTGCCATGCCGACCTTGCCAACGTACCAGCTGTCGGAGACCTCTTACCAGCCCACATCTATTCCACAAGGATTACCTGAG
CTGGAATTGGAAGCAATTGATAACCAATTTGGACAACCAGGAACAGGCGATCAGATTCCATGGACAAATAATACAGTGACAGCTATAAAT
CAGAGTAAATCAGAAGACCAGTGTATTAGCTCACAATTAGATGAGCTTCTCTGTCCACCCACAACAGTAGAAGGGAGAAATGATGAGAAG
GCTCTTCTTGAACAGCTGGTATCCTTCCTTAGTGGCAAAGATGAAACTGAGCTAGCTGAACTAGACAGAGCTCTGGGAATTGACAAACTT
GTTCAGGGGGGTGGATTAGATGTATTATCAGAGAGATTTCCACCACAACAAGCAACGCCACCTTTGATCATGGAAGAAAGACCCAACCTT
TATTCCCAGCCTTACTCTTCTCCTTCTCCTACTGCCAATCTCCCTAGCCCTTTCCAAGGCATGGTCAGGCAAAAACCTTCACTGGGGACG
ATGCCTGTTCAAGTAACACCTCCCCGAGGTGCTTTTTCACCTGGCATGGGCATGCAGCCCAGGCAAACTCTAAACAGACCTCCGGCTGCA
CCTAACCAGCTTCGACTTCAACTACAGCAGCGATTACAGGGACAACAGCAGTTGATACACCAAAATCGGCAAGCTATCTTAAACCAGTTT
GCAGCAACTGCTCCTGTTGGCATCAATATGAGATCAGGCATGCAACAGCAAATTACACCTCAGCCACCCCTGAATGCTCAAATGTTGGCA
CAACGTCAGCGGGAACTGTACAGTCAACAGCACCGACAGAGGCAGCTAATACAGCAGCAAAGAGCCATGCTTATGAGGCAGCAAAGCTTT
GGGAACAACCTCCCTCCCTCATCTGGACTACCAGTTCAAATGGGGAACCCCCGTCTTCCTCAGGGTGCTCCACAGCAATTCCCCTATCCA
CCAAACTATGGTACAAATCCAGGAACCCCACCTGCTTCTACCAGCCCGTTTTCACAACTAGCAGCAAATCCTGAAGCATCCTTGGCCAAC
CGCAACAGCATGGTGAGCAGAGGCATGACAGGAAACATAGGAGGACAGTTTGGCACTGGAATCAATCCTCAGATGCAGCAGAATGTCTTC
CAGTATCCAGGAGCAGGAATGGTTCCCCAAGGTGAGGCCAACTTTGCTCCATCTCTAAGCCCTGGGAGCTCCATGGTGCCGATGCCAATC
CCTCCTCCTCAGAGTTCTCTTCTCCAGCAAACTCCACCTGCCTCCGGGTATCAGTCACCAGACATGAAGGCCTGGCAGCAAGGAGCGATA
GGAAACAACAATGTGTTCAGTCAAGCTGTCCAGAACCAGCCCACGCCTGCACAGCCAGGAGTATACAACAACATGAGCATCACCGTTTCC
ATGGCAGGTGGAAATACGAATGTTCAGAACATGAACCCAATGATGGCCCAGATGCAGATGAGCTCTTTGCAGATGCCAGGAATGAACACT
GTGTGCCCTGAGCAGATAAATGATCCCGCACTGAGACACACAGGCCTCTACTGCAACCAGCTCTCATCCACTGACCTTCTCAAAACAGAA
GCAGATGGAACCCAGCAGGTGCAACAGGTTCAGGTGTTTGCTGACGTCCAGTGTACAGTGAATCTGGTAGGCGGGGACCCTTACCTGAAC
CAGCCTGGTCCACTGGGAACTCAAAAGCCCACGTCAGGACCACAGACCCCCCAGGCCCAGCAGAAGAGCCTCCTTCAGCAGCTACTGACT
GAATAACCACTTTTAAAGGAATGTGAAATTTAAATAATAGACATACAGAGATATACAAATATATTATATATTTTTCTGAGATTTTTGATA
TCTCAATCTGCAGCCATTCTTCAGGTCGTAGCATTTGGAGCAAAAAAAAAAAAAAAAAAAAAAAAAGGAGTTTGCTTTTGTCGGGAGATT
GAAAGATGTTTTTGTTTCTTTCTTTGTAAAGGCCTTGGATATTGAAAAAATACCAAGGCAGAACAGTTGGACAATCTATTTCTTGAGCCA
AATTTAATTATTCTTATTTTTGTAATCAGTCATTGGCTTCTTATCTGGATGAAGGCTTTTGGAGGAGAACCAAAACGACAAGTTCCAAGA
AGAAGATGAAGCTCCGCCTCCGCCGCTTAGTCCCAACCCTGCCCAGGAAGAAGGGCCCGTGGGGCTTTGCCTGTGCCCGTCCACCAAAGG
CTGTCATGTGTCTCGAAATCAGCAGCCCTCCCCATCCCAATCCCAGGCAGCTTGTGTGTACAATCAGCTTCTCTAGCAACTCTGTATCTG
TTGGCTTCAAGAGAATATTTTGCCTCCACATATGTACCCCTTCTCCTTTTTTTAAAGATGGATTTAAACCAAGATGCCTCCAGGAAAGAG
GACGAAATGAGTATATTCACAGAGGAATCCAAAAAATACAGTTTGGGGGAAAATGCAATAATTTTTGATGAGATGGGTGAAGGACAAGAA
GTGAGTTGTGTCAATTATTGTAGATACAATTTTCTGATTAAATCTGGAAAAATAAAAGGCAGCCTGTTTTTTCTGCTTTTATTGTATTAA
CAGCTGAGGTAGCTAAAGTTATTTAAAATAAAATTAAATTTATGATCCAAGTAGCTTATTTTTCCCTTTAAATCTCATTGTAAATATATT
TGATTTCTTGTAGAAATTGATTTCCTTCTGTTTAATTTTATGCTTTTATTATACTCTTGATTTTTCTAAATTTGTGTGTGAAATATAACA
TTGATTGAATTGCAGTTACATTTGGTTAGTAATATTTCATTATTTTAATAACTGTGATGTCATGTATGGATTTACTTTGGGGTTCAAATC
AAAATGTCACTGCCAGAAAGAGCTGTTCCAGCTGATCTAGAGCATACTGCCCTAGAGTGTCCCTGGGATCATCTGAACAGAAGTGCACAG
GCTACTTGTACAGAGAAAAAATTAATACTCAAAGGAAATCTTCATTTTTTAGATTGACTTTGGGAATTTGAATTTTCATCAGTGCAAATA
TAAATTTCTCTATCCTGCTCTGAGGCTAATTGGTACCATATTTTCCCTTTGTGTCTTGTGACTCTGCCACATCCCATCTCATCCTGGCCT
CTGAGTCAAGAACCCAGTGAACTGACTTTCTAGTTCTAGAAGTTCCGCTGCAAGGCCAGGAAAGCTTGAGAAAGGTATTGTGGAAGAAGC
AAAGGTAGACCCCCATCACTCACCTTTGTCTGCATCCCTGGGCCTGTGAATGATGACAGCACCTGACATTCTGCACCAGCTACCTCTGCC
TCCATGGCAGAGAAAAGGCCATAAGAACAGTGGAAGAGGAGCATGGACTCAGACTTCAAGGAAGAAGCCATTTCCCCAGGTCCTTCCTTC
TGCATCTCACCACCCCTAGTTACAAATAACTCCATTGAACAGCATCTATTCAGAAACTATGCCGAATAAAAAGATTGGTGGAAGGGCTCA
TGTGGTTAGCAACTATGAAACAGAAATAGGACACTCAGTTACAAACATTATCTCCTTTAGTTTTTCAGAAAATGCATCCCTGATTTCATT
CATTTCCAGCTTGAAAGCCAGCCATATTACTCTAGTCCCTACCAAACTGCTCTAGAAGGTCATTTCCATTTTGTTTGTGATATTTAGACG
CGCAGACTTCAGGAAGTTCACCTTTAACTTCAGCATTCCAGATGAAGTTTCCTGACTCAGTGCTTTTGCATAAGGAACTAGAAAAAAAAA
GTAAGGAAAATTGGAGATGCTAACATCCTCCCCCATCCCAACTGCACCTTAAAATATGCATGTCACCTTCAAGGTTTTATAATTGCACTG
TTTGTTTTATGTATGTACAGATTAAAATTATTGCTACATTTGAGGAAAATAAAATTGCTTGCTTCTATGTAATTCCTGTCATTCCACAGG
AAATTCACTTTTCCAGCTACTGAATAGAATTTGTTTAACAACCTCATGGGTTGCCTCTTCATTTACAGGGAAGAAATGAAATGTACATCT

>In-frame_PAX3_ENST00000392070_chr2_223085940_-_NCOA1_ENST00000406961_chr2_24949456_+_5377nt
ACTCGGTGTCACCACAGGAGGAGACTCAGGCAGGCCGCGCTCCAGCCTCACCAGGCTCCCCGGCTCGCCGTGGCTCTCTGAGCCCCCTTT
TCAGGGACCCCAGTCGCTGGAACATTTGCCCAGACTCGTACCAAACTTTTCCGCCCTGGGCTCGGGATCCTGGACTCCGGGGCCTCCCCG
TCCTCCCCTTTCCCGGGTTCCAGCTCCGGCCTCTGGACTAGGAACCGACAGCCCCCCTCCCCGCGTCCCTCCCTCTCTCTCCAGCCGTTT
TGGGGAGGGGCTCTCCACGCTCCGGATAGTTCCCGAGGGTCATCCGCGCCGCACTCGCCTTTCCGTTTCGCCTTCACCTGGATATAATTT
CCGAGCGAAGCTGCCCCCAGGATGACCACGCTGGCCGGCGCTGTGCCCAGGATGATGCGGCCGGGCCCGGGGCAGAACTACCCGCGTAGC
GGGTTCCCGCTGGAAGTGTCCACTCCCCTCGGCCAGGGCCGCGTCAACCAGCTCGGCGGTGTTTTTATCAACGGCAGGCCGCTGCCCAAC
CACATCCGCCACAAGATCGTGGAGATGGCCCACCACGGCATCCGGCCCTGCGTCATCTCGCGCCAGCTGCGCGTGTCCCACGGCTGCGTC
TCCAAGATCCTGTGCAGGTACCAGGAGACTGGCTCCATACGTCCTGGTGCCATCGGCGGCAGCAAGCCCAAGCAGGTGACAACGCCTGAC
GTGGAGAAGAAAATTGAGGAATACAAAAGAGAGAACCCGGGCATGTTCAGCTGGGAAATCCGAGACAAATTACTCAAGGACGCGGTCTGT
GATCGAAACACCGTGCCGTCAGTGAGTTCCATCAGCCGCATCCTGAGAAGTAAATTCGGGAAAGGTGAAGAGGAGGAGGCCGACTTGGAG
AGGAAGGAGGCAGAGGAAAGCGAGAAGAAGGCCAAACACAGCATCGACGGCATCCTGAGCGAGCGAGCCTCAGCACCCCAATCAGATGAA
GGCTCTGATATTGACTCTGAACCAGATTTACCACTAAAGAGGAAACAGCGCAGAAGCCGAACCACCTTCACAGCAGAACAGCTGGAGGAA
CTGGAGCGTGCTTTTGAGAGAACTCATTACCCTGACATTTATACTAGGGAGGAACTGGCCCAGAGGGCGAAGCTCACCGAGGCCCGAGTA
CAGGTCTGGTTTAGCAACCGCCGTGCAAGATGGAGGAAGCAAGCTGGGGCCAATCAACTGATGGCTTTCAACCATCTCATTCCCGGGGGG
TTCCCTCCCACTGCCATGCCGACCTTGCCAACGTACCAGCTGTCGGAGACCTCTTACCAGCCCACATCTATTCCACAAGGATTACCTGAG
CTGGAATTGGAAGCAATTGATAACCAATTTGGACAACCAGGAACAGGCGATCAGATTCCATGGACAAATAATACAGTGACAGCTATAAAT
CAGAGTAAATCAGAAGACCAGTGTATTAGCTCACAATTAGATGAGCTTCTCTGTCCACCCACAACAGTAGAAGGGAGAAATGATGAGAAG
GCTCTTCTTGAACAGCTGGTATCCTTCCTTAGTGGCAAAGATGAAACTGAGCTAGCTGAACTAGACAGAGCTCTGGGAATTGACAAACTT
GTTCAGGGGGGTGGATTAGATGTATTATCAGAGAGATTTCCACCACAACAAGCAACGCCACCTTTGATCATGGAAGAAAGACCCAACCTT
TATTCCCAGCCTTACTCTTCTCCTTCTCCTACTGCCAATCTCCCTAGCCCTTTCCAAGGCATGGTCAGGCAAAAACCTTCACTGGGGACG
ATGCCTGTTCAAGTAACACCTCCCCGAGGTGCTTTTTCACCTGGCATGGGCATGCAGCCCAGGCAAACTCTAAACAGACCTCCGGCTGCA
CCTAACCAGCTTCGACTTCAACTACAGCAGCGATTACAGGGACAACAGCAGTTGATACACCAAAATCGGCAAGCTATCTTAAACCAGTTT
GCAGCAACTGCTCCTGTTGGCATCAATATGAGATCAGGCATGCAACAGCAAATTACACCTCAGCCACCCCTGAATGCTCAAATGTTGGCA
CAACGTCAGCGGGAACTGTACAGTCAACAGCACCGACAGAGGCAGCTAATACAGCAGCAAAGAGCCATGCTTATGAGGCAGCAAAGCTTT
GGGAACAACCTCCCTCCCTCATCTGGACTACCAGTTCAAATGGGGAACCCCCGTCTTCCTCAGGGTGCTCCACAGCAATTCCCCTATCCA
CCAAACTATGGTACAAATCCAGGAACCCCACCTGCTTCTACCAGCCCGTTTTCACAACTAGCAGCAAATCCTGAAGCATCCTTGGCCAAC
CGCAACAGCATGGTGAGCAGAGGCATGACAGGAAACATAGGAGGACAGTTTGGCACTGGAATCAATCCTCAGATGCAGCAGAATGTCTTC
CAGTATCCAGGAGCAGGAATGGTTCCCCAAGGTGAGGCCAACTTTGCTCCATCTCTAAGCCCTGGGAGCTCCATGGTGCCGATGCCAATC
CCTCCTCCTCAGAGTTCTCTTCTCCAGCAAACTCCACCTGCCTCCGGGTATCAGTCACCAGACATGAAGGCCTGGCAGCAAGGAGCGATA
GGAAACAACAATGTGTTCAGTCAAGCTGTCCAGAACCAGCCCACGCCTGCACAGCCAGGAGTATACAACAACATGAGCATCACCGTTTCC
ATGGCAGGTGGAAATACGAATGTTCAGAACATGAACCCAATGATGGCCCAGATGCAGATGAGCTCTTTGCAGATGCCAGGAATGAACACT
GTGTGCCCTGAGCAGATAAATGATCCCGCACTGAGACACACAGGCCTCTACTGCAACCAGCTCTCATCCACTGACCTTCTCAAAACAGAA
GCAGATGGAACCCAGCAGGTGCAACAGGTTCAGGTGTTTGCTGACGTCCAGTGTACAGTGAATCTGGTAGGCGGGGACCCTTACCTGAAC
CAGCCTGGTCCACTGGGAACTCAAAAGCCCACGTCAGGACCACAGACCCCCCAGGCCCAGCAGAAGAGCCTCCTTCAGCAGCTACTGACT
GAATAACCACTTTTAAAGGAATGTGAAATTTAAATAATAGACATACAGAGATATACAAATATATTATATATTTTTCTGAGATTTTTGATA
TCTCAATCTGCAGCCATTCTTCAGGTCGTAGCATTTGGAGCAAAAAAAAAAAAAAAAAAAAAAAAAGGAGTTTGCTTTTGTCGGGAGATT
GAAAGATGTTTTTGTTTCTTTCTTTGTAAAGGCCTTGGATATTGAAAAAATACCAAGGCAGAACAGTTGGACAATCTATTTCTTGAGCCA
AATTTAATTATTCTTATTTTTGTAATCAGTCATTGGCTTCTTATCTGGATGAAGGCTTTTGGAGGAGAACCAAAACGACAAGTTCCAAGA
AGAAGATGAAGCTCCGCCTCCGCCGCTTAGTCCCAACCCTGCCCAGGAAGAAGGGCCCGTGGGGCTTTGCCTGTGCCCGTCCACCAAAGG
CTGTCATGTGTCTCGAAATCAGCAGCCCTCCCCATCCCAATCCCAGGCAGCTTGTGTGTACAATCAGCTTCTCTAGCAACTCTGTATCTG
TTGGCTTCAAGAGAATATTTTGCCTCCACATATGTACCCCTTCTCCTTTTTTTAAAGATGGATTTAAACCAAGATGCCTCCAGGAAAGAG
GACGAAATGAGTATATTCACAGAGGAATCCAAAAAATACAGTTTGGGGGAAAATGCAATAATTTTTGATGAGATGGGTGAAGGACAAGAA
GTGAGTTGTGTCAATTATTGTAGATACAATTTTCTGATTAAATCTGGAAAAATAAAAGGCAGCCTGTTTTTTCTGCTTTTATTGTATTAA
CAGCTGAGGTAGCTAAAGTTATTTAAAATAAAATTAAATTTATGATCCAAGTAGCTTATTTTTCCCTTTAAATCTCATTGTAAATATATT
TGATTTCTTGTAGAAATTGATTTCCTTCTGTTTAATTTTATGCTTTTATTATACTCTTGATTTTTCTAAATTTGTGTGTGAAATATAACA
TTGATTGAATTGCAGTTACATTTGGTTAGTAATATTTCATTATTTTAATAACTGTGATGTCATGTATGGATTTACTTTGGGGTTCAAATC
AAAATGTCACTGCCAGAAAGAGCTGTTCCAGCTGATCTAGAGCATACTGCCCTAGAGTGTCCCTGGGATCATCTGAACAGAAGTGCACAG
GCTACTTGTACAGAGAAAAAATTAATACTCAAAGGAAATCTTCATTTTTTAGATTGACTTTGGGAATTTGAATTTTCATCAGTGCAAATA
TAAATTTCTCTATCCTGCTCTGAGGCTAATTGGTACCATATTTTCCCTTTGTGTCTTGTGACTCTGCCACATCCCATCTCATCCTGGCCT
CTGAGTCAAGAACCCAGTGAACTGACTTTCTAGTTCTAGAAGTTCCGCTGCAAGGCCAGGAAAGCTTGAGAAAGGTATTGTGGAAGAAGC
AAAGGTAGACCCCCATCACTCACCTTTGTCTGCATCCCTGGGCCTGTGAATGATGACAGCACCTGACATTCTGCACCAGCTACCTCTGCC
TCCATGGCAGAGAAAAGGCCATAAGAACAGTGGAAGAGGAGCATGGACTCAGACTTCAAGGAAGAAGCCATTTCCCCAGGTCCTTCCTTC
TGCATCTCACCACCCCTAGTTACAAATAACTCCATTGAACAGCATCTATTCAGAAACTATGCCGAATAAAAAGATTGGTGGAAGGGCTCA
TGTGGTTAGCAACTATGAAACAGAAATAGGACACTCAGTTACAAACATTATCTCCTTTAGTTTTTCAGAAAATGCATCCCTGATTTCATT
CATTTCCAGCTTGAAAGCCAGCCATATTACTCTAGTCCCTACCAAACTGCTCTAGAAGGTCATTTCCATTTTGTTTGTGATATTTAGACG
CGCAGACTTCAGGAAGTTCACCTTTAACTTCAGCATTCCAGATGAAGTTTCCTGACTCAGTGCTTTTGCATAAGGAACTAGAAAAAAAAA
GTAAGGAAAATTGGAGATGCTAACATCCTCCCCCATCCCAACTGCACCTTAAAATATGCATGTCACCTTCAAGGTTTTATAATTGCACTG
TTTGTTTTATGTATGTACAGATTAAAATTATTGCTACATTTGAGGAAAATAAAATTGCTTGCTTCTATGTAATTCCTGTCATTCCACAGG
AAATTCACTTTTCCAGCTACTGAATAGAATTTGTTTAACAACCTCATGGGTTGCCTCTTCATTTACAGGGAAGAAATGAAATGTACATCT

>In-frame_PAX3_ENST00000409551_chr2_223085940_-_NCOA1_ENST00000406961_chr2_24949456_+_5273nt
AGTCGCTGGAACATTTGCCCAGACTCGTACCAAACTTTTCCGCCCTGGGCTCGGGATCCTGGACTCCGGGGCCTCCCCGTCCTCCCCTTT
CCCGGGTTCCAGCTCCGGCCTCTGGACTAGGAACCGACAGCCCCCCTCCCCGCGTCCCTCCCTCTCTCTCCAGCCGTTTTGGGGAGGGGC
TCTCCACGCTCCGGATAGTTCCCGAGGGTCATCCGCGCCGCACTCGCCTTTCCGTTTCGCCTTCACCTGGATATAATTTCCGAGCGAAGC
TGCCCCCAGGATGACCACGCTGGCCGGCGCTGTGCCCAGGATGATGCGGCCGGGCCCGGGGCAGAACTACCCGCGTAGCGGGTTCCCGCT
GGAAGTGTCCACTCCCCTCGGCCAGGGCCGCGTCAACCAGCTCGGCGGTGTTTTTATCAACGGCAGGCCGCTGCCCAACCACATCCGCCA
CAAGATCGTGGAGATGGCCCACCACGGCATCCGGCCCTGCGTCATCTCGCGCCAGCTGCGCGTGTCCCACGGCTGCGTCTCCAAGATCCT
GTGCAGGTACCAGGAGACTGGCTCCATACGTCCTGGTGCCATCGGCGGCAGCAAGCCCAAGGTGACAACGCCTGACGTGGAGAAGAAAAT
TGAGGAATACAAAAGAGAGAACCCGGGCATGTTCAGCTGGGAAATCCGAGACAAATTACTCAAGGACGCGGTCTGTGATCGAAACACCGT
GCCGTCAGTGAGTTCCATCAGCCGCATCCTGAGAAGTAAATTCGGGAAAGGTGAAGAGGAGGAGGCCGACTTGGAGAGGAAGGAGGCAGA
GGAAAGCGAGAAGAAGGCCAAACACAGCATCGACGGCATCCTGAGCGAGCGAGCCTCAGCACCCCAATCAGATGAAGGCTCTGATATTGA
CTCTGAACCAGATTTACCACTAAAGAGGAAACAGCGCAGAAGCCGAACCACCTTCACAGCAGAACAGCTGGAGGAACTGGAGCGTGCTTT
TGAGAGAACTCATTACCCTGACATTTATACTAGGGAGGAACTGGCCCAGAGGGCGAAGCTCACCGAGGCCCGAGTACAGGTCTGGTTTAG
CAACCGCCGTGCAAGATGGAGGAAGCAAGCTGGGGCCAATCAACTGATGGCTTTCAACCATCTCATTCCCGGGGGGTTCCCTCCCACTGC
CATGCCGACCTTGCCAACGTACCAGCTGTCGGAGACCTCTTACCAGCCCACATCTATTCCACAAGGATTACCTGAGCTGGAATTGGAAGC
AATTGATAACCAATTTGGACAACCAGGAACAGGCGATCAGATTCCATGGACAAATAATACAGTGACAGCTATAAATCAGAGTAAATCAGA
AGACCAGTGTATTAGCTCACAATTAGATGAGCTTCTCTGTCCACCCACAACAGTAGAAGGGAGAAATGATGAGAAGGCTCTTCTTGAACA
GCTGGTATCCTTCCTTAGTGGCAAAGATGAAACTGAGCTAGCTGAACTAGACAGAGCTCTGGGAATTGACAAACTTGTTCAGGGGGGTGG
ATTAGATGTATTATCAGAGAGATTTCCACCACAACAAGCAACGCCACCTTTGATCATGGAAGAAAGACCCAACCTTTATTCCCAGCCTTA
CTCTTCTCCTTCTCCTACTGCCAATCTCCCTAGCCCTTTCCAAGGCATGGTCAGGCAAAAACCTTCACTGGGGACGATGCCTGTTCAAGT
AACACCTCCCCGAGGTGCTTTTTCACCTGGCATGGGCATGCAGCCCAGGCAAACTCTAAACAGACCTCCGGCTGCACCTAACCAGCTTCG
ACTTCAACTACAGCAGCGATTACAGGGACAACAGCAGTTGATACACCAAAATCGGCAAGCTATCTTAAACCAGTTTGCAGCAACTGCTCC
TGTTGGCATCAATATGAGATCAGGCATGCAACAGCAAATTACACCTCAGCCACCCCTGAATGCTCAAATGTTGGCACAACGTCAGCGGGA
ACTGTACAGTCAACAGCACCGACAGAGGCAGCTAATACAGCAGCAAAGAGCCATGCTTATGAGGCAGCAAAGCTTTGGGAACAACCTCCC
TCCCTCATCTGGACTACCAGTTCAAATGGGGAACCCCCGTCTTCCTCAGGGTGCTCCACAGCAATTCCCCTATCCACCAAACTATGGTAC
AAATCCAGGAACCCCACCTGCTTCTACCAGCCCGTTTTCACAACTAGCAGCAAATCCTGAAGCATCCTTGGCCAACCGCAACAGCATGGT
GAGCAGAGGCATGACAGGAAACATAGGAGGACAGTTTGGCACTGGAATCAATCCTCAGATGCAGCAGAATGTCTTCCAGTATCCAGGAGC
AGGAATGGTTCCCCAAGGTGAGGCCAACTTTGCTCCATCTCTAAGCCCTGGGAGCTCCATGGTGCCGATGCCAATCCCTCCTCCTCAGAG
TTCTCTTCTCCAGCAAACTCCACCTGCCTCCGGGTATCAGTCACCAGACATGAAGGCCTGGCAGCAAGGAGCGATAGGAAACAACAATGT
GTTCAGTCAAGCTGTCCAGAACCAGCCCACGCCTGCACAGCCAGGAGTATACAACAACATGAGCATCACCGTTTCCATGGCAGGTGGAAA
TACGAATGTTCAGAACATGAACCCAATGATGGCCCAGATGCAGATGAGCTCTTTGCAGATGCCAGGAATGAACACTGTGTGCCCTGAGCA
GATAAATGATCCCGCACTGAGACACACAGGCCTCTACTGCAACCAGCTCTCATCCACTGACCTTCTCAAAACAGAAGCAGATGGAACCCA
GCAGGTGCAACAGGTTCAGGTGTTTGCTGACGTCCAGTGTACAGTGAATCTGGTAGGCGGGGACCCTTACCTGAACCAGCCTGGTCCACT
GGGAACTCAAAAGCCCACGTCAGGACCACAGACCCCCCAGGCCCAGCAGAAGAGCCTCCTTCAGCAGCTACTGACTGAATAACCACTTTT
AAAGGAATGTGAAATTTAAATAATAGACATACAGAGATATACAAATATATTATATATTTTTCTGAGATTTTTGATATCTCAATCTGCAGC
CATTCTTCAGGTCGTAGCATTTGGAGCAAAAAAAAAAAAAAAAAAAAAAAAAGGAGTTTGCTTTTGTCGGGAGATTGAAAGATGTTTTTG
TTTCTTTCTTTGTAAAGGCCTTGGATATTGAAAAAATACCAAGGCAGAACAGTTGGACAATCTATTTCTTGAGCCAAATTTAATTATTCT
TATTTTTGTAATCAGTCATTGGCTTCTTATCTGGATGAAGGCTTTTGGAGGAGAACCAAAACGACAAGTTCCAAGAAGAAGATGAAGCTC
CGCCTCCGCCGCTTAGTCCCAACCCTGCCCAGGAAGAAGGGCCCGTGGGGCTTTGCCTGTGCCCGTCCACCAAAGGCTGTCATGTGTCTC
GAAATCAGCAGCCCTCCCCATCCCAATCCCAGGCAGCTTGTGTGTACAATCAGCTTCTCTAGCAACTCTGTATCTGTTGGCTTCAAGAGA
ATATTTTGCCTCCACATATGTACCCCTTCTCCTTTTTTTAAAGATGGATTTAAACCAAGATGCCTCCAGGAAAGAGGACGAAATGAGTAT
ATTCACAGAGGAATCCAAAAAATACAGTTTGGGGGAAAATGCAATAATTTTTGATGAGATGGGTGAAGGACAAGAAGTGAGTTGTGTCAA
TTATTGTAGATACAATTTTCTGATTAAATCTGGAAAAATAAAAGGCAGCCTGTTTTTTCTGCTTTTATTGTATTAACAGCTGAGGTAGCT
AAAGTTATTTAAAATAAAATTAAATTTATGATCCAAGTAGCTTATTTTTCCCTTTAAATCTCATTGTAAATATATTTGATTTCTTGTAGA
AATTGATTTCCTTCTGTTTAATTTTATGCTTTTATTATACTCTTGATTTTTCTAAATTTGTGTGTGAAATATAACATTGATTGAATTGCA
GTTACATTTGGTTAGTAATATTTCATTATTTTAATAACTGTGATGTCATGTATGGATTTACTTTGGGGTTCAAATCAAAATGTCACTGCC
AGAAAGAGCTGTTCCAGCTGATCTAGAGCATACTGCCCTAGAGTGTCCCTGGGATCATCTGAACAGAAGTGCACAGGCTACTTGTACAGA
GAAAAAATTAATACTCAAAGGAAATCTTCATTTTTTAGATTGACTTTGGGAATTTGAATTTTCATCAGTGCAAATATAAATTTCTCTATC
CTGCTCTGAGGCTAATTGGTACCATATTTTCCCTTTGTGTCTTGTGACTCTGCCACATCCCATCTCATCCTGGCCTCTGAGTCAAGAACC
CAGTGAACTGACTTTCTAGTTCTAGAAGTTCCGCTGCAAGGCCAGGAAAGCTTGAGAAAGGTATTGTGGAAGAAGCAAAGGTAGACCCCC
ATCACTCACCTTTGTCTGCATCCCTGGGCCTGTGAATGATGACAGCACCTGACATTCTGCACCAGCTACCTCTGCCTCCATGGCAGAGAA
AAGGCCATAAGAACAGTGGAAGAGGAGCATGGACTCAGACTTCAAGGAAGAAGCCATTTCCCCAGGTCCTTCCTTCTGCATCTCACCACC
CCTAGTTACAAATAACTCCATTGAACAGCATCTATTCAGAAACTATGCCGAATAAAAAGATTGGTGGAAGGGCTCATGTGGTTAGCAACT
ATGAAACAGAAATAGGACACTCAGTTACAAACATTATCTCCTTTAGTTTTTCAGAAAATGCATCCCTGATTTCATTCATTTCCAGCTTGA
AAGCCAGCCATATTACTCTAGTCCCTACCAAACTGCTCTAGAAGGTCATTTCCATTTTGTTTGTGATATTTAGACGCGCAGACTTCAGGA
AGTTCACCTTTAACTTCAGCATTCCAGATGAAGTTTCCTGACTCAGTGCTTTTGCATAAGGAACTAGAAAAAAAAAGTAAGGAAAATTGG
AGATGCTAACATCCTCCCCCATCCCAACTGCACCTTAAAATATGCATGTCACCTTCAAGGTTTTATAATTGCACTGTTTGTTTTATGTAT
GTACAGATTAAAATTATTGCTACATTTGAGGAAAATAAAATTGCTTGCTTCTATGTAATTCCTGTCATTCCACAGGAAATTCACTTTTCC
AGCTACTGAATAGAATTTGTTTAACAACCTCATGGGTTGCCTCTTCATTTACAGGGAAGAAATGAAATGTACATCTGCAGAAATTGCCAA


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FusionGenePPI for PAX3_NCOA1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
PAX3IPO13, SOX10, DAXX, MSX1, MEOX1, MEOX2, TBP, PSMD4, RAD23B, HDAC10, TRIM28, HDAC1, POU3F2, TAF1, PCTP, SPIN1, SKAP1, FOXE1, FZR1, NELL2NCOA1NR1H4, FOS, JUN, NFKB1, AR, CIITA, NR1I2, SMARCE1, BCL3, NR3C1, YWHAQ, STAT6, TRIP4, ESR1, SMARCA4, CREBBP, KAT2B, PRMT1, NR4A1, PPARA, NCOR1, FOXA2, RARB, GTF2B, TBP, TEAD2, TEAD1, STAT3, HNF4A, HIF1A, NR5A1, CCND1, ESRRG, ESR2, PGR, THRB, NCOA2, TRIM21, NR2F6, PPARGC1A, SNW1, RXRA, STAT5A, CARM1, NKX2-1, PPARG, NCOA3, VDR, THRA, RARA, EP300, RBBP6, RARG, PPARD, RORA, NCOA6, TP53, UBE2L3, COPS5, NCOA1, ANIB1, TRIM24, KANK2, AHR, CXADR, PAGR1, RORB, HNF4G, ESRRA, NR5A2, NR6A1, ASCC1, RABGGTB, NR1I3, ARID1A, EZH2, BRCA1, NR1H2, NR1H3, RXRB, SRF, HNF1A, NR3C2, FOXO1, RNF4, ARNT, ETS2, ETS1, SMARCC1, SF1, WDHD1, SYTL2, HSPA2, HSPA5, KCTD3, VCP, ITCH, TRIP11, UBR5, SMAD3, ANKRD11, NR4A2, FAM131B, C19orf57, PLA2G10, TRPC4AP, SLX1A


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneNCOA1chr2:223085940chr2:24949456ENST00000288599+1122781_9888662199CREBBP
TgeneNCOA1chr2:223085940chr2:24949456ENST00000348332+1121781_9888661442CREBBP
TgeneNCOA1chr2:223085940chr2:24949456ENST00000395856+1121781_9888661441CREBBP
TgeneNCOA1chr2:223085940chr2:24949456ENST00000405141+1425781_9888662183CREBBP
TgeneNCOA1chr2:223085940chr2:24949456ENST00000406961+1323781_9888661442CREBBP
TgeneNCOA1chr2:223085940chr2:24949456ENST00000538539+1223781_9888661422CREBBP
TgeneNCOA1chr2:223085940chr2:24949456ENST00000288599+1122361_5678662199STAT3
TgeneNCOA1chr2:223085940chr2:24949456ENST00000348332+1121361_5678661442STAT3
TgeneNCOA1chr2:223085940chr2:24949456ENST00000395856+1121361_5678661441STAT3
TgeneNCOA1chr2:223085940chr2:24949456ENST00000405141+1425361_5678662183STAT3
TgeneNCOA1chr2:223085940chr2:24949456ENST00000406961+1323361_5678661442STAT3
TgeneNCOA1chr2:223085940chr2:24949456ENST00000538539+1223361_5678661422STAT3


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for PAX3_NCOA1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for PAX3_NCOA1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgenePAX3C1847800Waardenburg Syndrome Type 114ORPHANET;UNIPROT
HgenePAX3C0079661Klein's Syndrome5ORPHANET;UNIPROT
HgenePAX3C0080178Spina Bifida4CTD_human
HgenePAX3C0027794Neural Tube Defects3CTD_human
HgenePAX3C1852510Craniofacial deafness hand syndrome2CTD_human;ORPHANET;UNIPROT
HgenePAX3C0011053Deafness1CTD_human;HPO
HgenePAX3C0018566Congenital Hand Deformities1CTD_human
HgenePAX3C0376634Craniofacial Abnormalities1CTD_human
HgenePAX3C0497552Congenital neurologic anomalies1CTD_human
HgenePAX3C1261473Sarcoma1CTD_human
HgenePAX3C1710096Sinonasal undifferentiated carcinoma1CTD_human
HgenePAX3C3266898Waardenburg Syndrome1CTD_human
TgeneNCOA1C0014175Endometriosis1CTD_human
TgeneNCOA1C0024668Mammary Neoplasms, Experimental1CTD_human
TgeneNCOA1C0027627Neoplasm Metastasis1CTD_human
TgeneNCOA1C0033578Prostatic Neoplasms1CTD_human
TgeneNCOA1C1458155Mammary Neoplasms1CTD_human