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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDiseases

Fusion gene ID: 25974

FusionGeneSummary for PARD3_CUL2

check button Fusion gene summary
Fusion gene informationFusion gene name: PARD3_CUL2
Fusion gene ID: 25974
HgeneTgene
Gene symbol

PARD3

CUL2

Gene ID

56288

8453

Gene namepar-3 family cell polarity regulatorcullin 2
SynonymsASIP|Baz|PAR3|PAR3alpha|PARD-3|PARD3A|PPP1R118|SE2-5L16|SE2-5LT1|SE2-5T2-
Cytomap

10p11.22-p11.21

10p11.21

Type of geneprotein-codingprotein-coding
Descriptionpartitioning defective 3 homologCTCL tumor antigen se2-5PAR3-alphaatypical PKC isotype-specific interacting proteinbazookapar-3 family cell polarity regulator alphapar-3 partitioning defective 3 homologprotein phosphatase 1, regulatory subunit 118cullin-2CUL-2testis secretory sperm-binding protein Li 238E
Modification date2018052320180523
UniProtAcc

Q8TEW0

Q13617

Ensembl transtripts involved in fusion geneENST00000545260, ENST00000545693, 
ENST00000350537, ENST00000346874, 
ENST00000374789, ENST00000374790, 
ENST00000374794, ENST00000374788, 
ENST00000466092, ENST00000374776, 
ENST00000340077, ENST00000544292, 
ENST00000374773, ENST00000374768, 
ENST00000374746, ENST00000374748, 
ENST00000374749, ENST00000374751, 
ENST00000602371, ENST00000374742, 
ENST00000537177, ENST00000478044, 
Fusion gene scores* DoF score22 X 13 X 12=34324 X 4 X 4=64
# samples 265
** MAII scorelog2(26/3432*10)=-3.72246602447109
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/64*10)=-0.356143810225275
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PARD3 [Title/Abstract] AND CUL2 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationTumor suppressor gene involved fusion gene, in-frame but not retained their domain.
Tumor suppressor gene involved fusion gene, retained protein feature but frameshift.
DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVBLCATCGA-4Z-AA87-01APARD3chr10

34985246

-CUL2chr10

35360267

-
TCGARVBRCATCGA-OL-A66P-01APARD3chr10

34985246

-CUL2chr10

35305322

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000545260ENST00000374746PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000545260ENST00000374748PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000545260ENST00000374749PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000545260ENST00000374751PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000545260ENST00000602371PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000545260ENST00000374742PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000545260ENST00000537177PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000545260ENST00000478044PARD3chr10

34985246

-CUL2chr10

35360267

-
In-frameENST00000545693ENST00000374746PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000545693ENST00000374748PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000545693ENST00000374749PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000545693ENST00000374751PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000545693ENST00000602371PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000545693ENST00000374742PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000545693ENST00000537177PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000545693ENST00000478044PARD3chr10

34985246

-CUL2chr10

35360267

-
In-frameENST00000350537ENST00000374746PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000350537ENST00000374748PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000350537ENST00000374749PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000350537ENST00000374751PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000350537ENST00000602371PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000350537ENST00000374742PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000350537ENST00000537177PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000350537ENST00000478044PARD3chr10

34985246

-CUL2chr10

35360267

-
In-frameENST00000346874ENST00000374746PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000346874ENST00000374748PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000346874ENST00000374749PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000346874ENST00000374751PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000346874ENST00000602371PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000346874ENST00000374742PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000346874ENST00000537177PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000346874ENST00000478044PARD3chr10

34985246

-CUL2chr10

35360267

-
In-frameENST00000374789ENST00000374746PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000374789ENST00000374748PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000374789ENST00000374749PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000374789ENST00000374751PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000374789ENST00000602371PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000374789ENST00000374742PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000374789ENST00000537177PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000374789ENST00000478044PARD3chr10

34985246

-CUL2chr10

35360267

-
In-frameENST00000374790ENST00000374746PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000374790ENST00000374748PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000374790ENST00000374749PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000374790ENST00000374751PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000374790ENST00000602371PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000374790ENST00000374742PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000374790ENST00000537177PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000374790ENST00000478044PARD3chr10

34985246

-CUL2chr10

35360267

-
In-frameENST00000374794ENST00000374746PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000374794ENST00000374748PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000374794ENST00000374749PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000374794ENST00000374751PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000374794ENST00000602371PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000374794ENST00000374742PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000374794ENST00000537177PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000374794ENST00000478044PARD3chr10

34985246

-CUL2chr10

35360267

-
In-frameENST00000374788ENST00000374746PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000374788ENST00000374748PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000374788ENST00000374749PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000374788ENST00000374751PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000374788ENST00000602371PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000374788ENST00000374742PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000374788ENST00000537177PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000374788ENST00000478044PARD3chr10

34985246

-CUL2chr10

35360267

-
intron-3CDSENST00000466092ENST00000374746PARD3chr10

34985246

-CUL2chr10

35360267

-
intron-5UTRENST00000466092ENST00000374748PARD3chr10

34985246

-CUL2chr10

35360267

-
intron-5UTRENST00000466092ENST00000374749PARD3chr10

34985246

-CUL2chr10

35360267

-
intron-5UTRENST00000466092ENST00000374751PARD3chr10

34985246

-CUL2chr10

35360267

-
intron-5UTRENST00000466092ENST00000602371PARD3chr10

34985246

-CUL2chr10

35360267

-
intron-5UTRENST00000466092ENST00000374742PARD3chr10

34985246

-CUL2chr10

35360267

-
intron-5UTRENST00000466092ENST00000537177PARD3chr10

34985246

-CUL2chr10

35360267

-
intron-5UTRENST00000466092ENST00000478044PARD3chr10

34985246

-CUL2chr10

35360267

-
In-frameENST00000374776ENST00000374746PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000374776ENST00000374748PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000374776ENST00000374749PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000374776ENST00000374751PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000374776ENST00000602371PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000374776ENST00000374742PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000374776ENST00000537177PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000374776ENST00000478044PARD3chr10

34985246

-CUL2chr10

35360267

-
In-frameENST00000340077ENST00000374746PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000340077ENST00000374748PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000340077ENST00000374749PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000340077ENST00000374751PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000340077ENST00000602371PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000340077ENST00000374742PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000340077ENST00000537177PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000340077ENST00000478044PARD3chr10

34985246

-CUL2chr10

35360267

-
intron-3CDSENST00000544292ENST00000374746PARD3chr10

34985246

-CUL2chr10

35360267

-
intron-5UTRENST00000544292ENST00000374748PARD3chr10

34985246

-CUL2chr10

35360267

-
intron-5UTRENST00000544292ENST00000374749PARD3chr10

34985246

-CUL2chr10

35360267

-
intron-5UTRENST00000544292ENST00000374751PARD3chr10

34985246

-CUL2chr10

35360267

-
intron-5UTRENST00000544292ENST00000602371PARD3chr10

34985246

-CUL2chr10

35360267

-
intron-5UTRENST00000544292ENST00000374742PARD3chr10

34985246

-CUL2chr10

35360267

-
intron-5UTRENST00000544292ENST00000537177PARD3chr10

34985246

-CUL2chr10

35360267

-
intron-5UTRENST00000544292ENST00000478044PARD3chr10

34985246

-CUL2chr10

35360267

-
In-frameENST00000374773ENST00000374746PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000374773ENST00000374748PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000374773ENST00000374749PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000374773ENST00000374751PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000374773ENST00000602371PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000374773ENST00000374742PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000374773ENST00000537177PARD3chr10

34985246

-CUL2chr10

35360267

-
5CDS-5UTRENST00000374773ENST00000478044PARD3chr10

34985246

-CUL2chr10

35360267

-
intron-3CDSENST00000374768ENST00000374746PARD3chr10

34985246

-CUL2chr10

35360267

-
intron-5UTRENST00000374768ENST00000374748PARD3chr10

34985246

-CUL2chr10

35360267

-
intron-5UTRENST00000374768ENST00000374749PARD3chr10

34985246

-CUL2chr10

35360267

-
intron-5UTRENST00000374768ENST00000374751PARD3chr10

34985246

-CUL2chr10

35360267

-
intron-5UTRENST00000374768ENST00000602371PARD3chr10

34985246

-CUL2chr10

35360267

-
intron-5UTRENST00000374768ENST00000374742PARD3chr10

34985246

-CUL2chr10

35360267

-
intron-5UTRENST00000374768ENST00000537177PARD3chr10

34985246

-CUL2chr10

35360267

-
intron-5UTRENST00000374768ENST00000478044PARD3chr10

34985246

-CUL2chr10

35360267

-
Frame-shiftENST00000545260ENST00000374746PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000545260ENST00000374748PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000545260ENST00000374749PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000545260ENST00000374751PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000545260ENST00000602371PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000545260ENST00000374742PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000545260ENST00000537177PARD3chr10

34985246

-CUL2chr10

35305322

-
5CDS-intronENST00000545260ENST00000478044PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000545693ENST00000374746PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000545693ENST00000374748PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000545693ENST00000374749PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000545693ENST00000374751PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000545693ENST00000602371PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000545693ENST00000374742PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000545693ENST00000537177PARD3chr10

34985246

-CUL2chr10

35305322

-
5CDS-intronENST00000545693ENST00000478044PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000350537ENST00000374746PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000350537ENST00000374748PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000350537ENST00000374749PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000350537ENST00000374751PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000350537ENST00000602371PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000350537ENST00000374742PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000350537ENST00000537177PARD3chr10

34985246

-CUL2chr10

35305322

-
5CDS-intronENST00000350537ENST00000478044PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000346874ENST00000374746PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000346874ENST00000374748PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000346874ENST00000374749PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000346874ENST00000374751PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000346874ENST00000602371PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000346874ENST00000374742PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000346874ENST00000537177PARD3chr10

34985246

-CUL2chr10

35305322

-
5CDS-intronENST00000346874ENST00000478044PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000374789ENST00000374746PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000374789ENST00000374748PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000374789ENST00000374749PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000374789ENST00000374751PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000374789ENST00000602371PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000374789ENST00000374742PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000374789ENST00000537177PARD3chr10

34985246

-CUL2chr10

35305322

-
5CDS-intronENST00000374789ENST00000478044PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000374790ENST00000374746PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000374790ENST00000374748PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000374790ENST00000374749PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000374790ENST00000374751PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000374790ENST00000602371PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000374790ENST00000374742PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000374790ENST00000537177PARD3chr10

34985246

-CUL2chr10

35305322

-
5CDS-intronENST00000374790ENST00000478044PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000374794ENST00000374746PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000374794ENST00000374748PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000374794ENST00000374749PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000374794ENST00000374751PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000374794ENST00000602371PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000374794ENST00000374742PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000374794ENST00000537177PARD3chr10

34985246

-CUL2chr10

35305322

-
5CDS-intronENST00000374794ENST00000478044PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000374788ENST00000374746PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000374788ENST00000374748PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000374788ENST00000374749PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000374788ENST00000374751PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000374788ENST00000602371PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000374788ENST00000374742PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000374788ENST00000537177PARD3chr10

34985246

-CUL2chr10

35305322

-
5CDS-intronENST00000374788ENST00000478044PARD3chr10

34985246

-CUL2chr10

35305322

-
intron-3CDSENST00000466092ENST00000374746PARD3chr10

34985246

-CUL2chr10

35305322

-
intron-3CDSENST00000466092ENST00000374748PARD3chr10

34985246

-CUL2chr10

35305322

-
intron-3CDSENST00000466092ENST00000374749PARD3chr10

34985246

-CUL2chr10

35305322

-
intron-3CDSENST00000466092ENST00000374751PARD3chr10

34985246

-CUL2chr10

35305322

-
intron-3CDSENST00000466092ENST00000602371PARD3chr10

34985246

-CUL2chr10

35305322

-
intron-3CDSENST00000466092ENST00000374742PARD3chr10

34985246

-CUL2chr10

35305322

-
intron-3CDSENST00000466092ENST00000537177PARD3chr10

34985246

-CUL2chr10

35305322

-
intron-intronENST00000466092ENST00000478044PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000374776ENST00000374746PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000374776ENST00000374748PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000374776ENST00000374749PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000374776ENST00000374751PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000374776ENST00000602371PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000374776ENST00000374742PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000374776ENST00000537177PARD3chr10

34985246

-CUL2chr10

35305322

-
5CDS-intronENST00000374776ENST00000478044PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000340077ENST00000374746PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000340077ENST00000374748PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000340077ENST00000374749PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000340077ENST00000374751PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000340077ENST00000602371PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000340077ENST00000374742PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000340077ENST00000537177PARD3chr10

34985246

-CUL2chr10

35305322

-
5CDS-intronENST00000340077ENST00000478044PARD3chr10

34985246

-CUL2chr10

35305322

-
intron-3CDSENST00000544292ENST00000374746PARD3chr10

34985246

-CUL2chr10

35305322

-
intron-3CDSENST00000544292ENST00000374748PARD3chr10

34985246

-CUL2chr10

35305322

-
intron-3CDSENST00000544292ENST00000374749PARD3chr10

34985246

-CUL2chr10

35305322

-
intron-3CDSENST00000544292ENST00000374751PARD3chr10

34985246

-CUL2chr10

35305322

-
intron-3CDSENST00000544292ENST00000602371PARD3chr10

34985246

-CUL2chr10

35305322

-
intron-3CDSENST00000544292ENST00000374742PARD3chr10

34985246

-CUL2chr10

35305322

-
intron-3CDSENST00000544292ENST00000537177PARD3chr10

34985246

-CUL2chr10

35305322

-
intron-intronENST00000544292ENST00000478044PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000374773ENST00000374746PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000374773ENST00000374748PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000374773ENST00000374749PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000374773ENST00000374751PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000374773ENST00000602371PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000374773ENST00000374742PARD3chr10

34985246

-CUL2chr10

35305322

-
Frame-shiftENST00000374773ENST00000537177PARD3chr10

34985246

-CUL2chr10

35305322

-
5CDS-intronENST00000374773ENST00000478044PARD3chr10

34985246

-CUL2chr10

35305322

-
intron-3CDSENST00000374768ENST00000374746PARD3chr10

34985246

-CUL2chr10

35305322

-
intron-3CDSENST00000374768ENST00000374748PARD3chr10

34985246

-CUL2chr10

35305322

-
intron-3CDSENST00000374768ENST00000374749PARD3chr10

34985246

-CUL2chr10

35305322

-
intron-3CDSENST00000374768ENST00000374751PARD3chr10

34985246

-CUL2chr10

35305322

-
intron-3CDSENST00000374768ENST00000602371PARD3chr10

34985246

-CUL2chr10

35305322

-
intron-3CDSENST00000374768ENST00000374742PARD3chr10

34985246

-CUL2chr10

35305322

-
intron-3CDSENST00000374768ENST00000537177PARD3chr10

34985246

-CUL2chr10

35305322

-
intron-intronENST00000374768ENST00000478044PARD3chr10

34985246

-CUL2chr10

35305322

-

Top

FusionProtFeatures for PARD3_CUL2


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
PARD3

Q8TEW0

CUL2

Q13617

Core component of multiple cullin-RING-based ECS(ElonginB/C-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligasecomplexes, which mediate the ubiquitination of target proteins.ECS complexes and ARIH1 collaborate in tandem to mediateubiquitination of target proteins (PubMed:27565346). May serve asa rigid scaffold in the complex and may contribute to catalysisthrough positioning of the substrate and the ubiquitin-conjugatingenzyme. The E3 ubiquitin-protein ligase activity of the complex isdependent on the neddylation of the cullin subunit and isinhibited by the association of the deneddylated cullin subunitwith TIP120A/CAND1. The functional specificity of the ECS complexdepends on the substrate recognition component. ECS(VHL) mediatesthe ubiquitination of hypoxia-inducible factor (HIF).{ECO:0000269|PubMed:10973499, ECO:0000269|PubMed:11384984,ECO:0000269|PubMed:27565346, ECO:0000269|PubMed:9122164}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePARD3chr10:34985246chr10:35360267ENST00000340077-2211049_1077741032Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34985246chr10:35360267ENST00000340077-2211151_1174741032Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34985246chr10:35360267ENST00000340077-2211201_1224741032Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34985246chr10:35360267ENST00000340077-2211280_1301741032Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34985246chr10:35360267ENST00000346874-2241049_1077741320Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34985246chr10:35360267ENST00000346874-2241151_1174741320Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34985246chr10:35360267ENST00000346874-2241201_1224741320Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34985246chr10:35360267ENST00000346874-2241280_1301741320Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34985246chr10:35360267ENST00000350537-2241049_1077741311Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34985246chr10:35360267ENST00000350537-2241151_1174741311Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34985246chr10:35360267ENST00000350537-2241201_1224741311Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34985246chr10:35360267ENST00000350537-2241280_1301741311Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34985246chr10:35360267ENST00000374776-2201049_107774989Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34985246chr10:35360267ENST00000374776-2201151_117474989Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34985246chr10:35360267ENST00000374776-2201201_122474989Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34985246chr10:35360267ENST00000374776-2201280_130174989Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34985246chr10:35360267ENST00000374788-2251049_1077741354Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34985246chr10:35360267ENST00000374788-2251151_1174741354Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34985246chr10:35360267ENST00000374788-2251201_1224741354Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34985246chr10:35360267ENST00000374788-2251280_1301741354Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34985246chr10:35360267ENST00000374789-2251049_1077741357Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34985246chr10:35360267ENST00000374789-2251151_1174741357Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34985246chr10:35360267ENST00000374789-2251201_1224741357Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34985246chr10:35360267ENST00000374789-2251280_1301741357Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34985246chr10:35360267ENST00000374794-2211049_1077741245Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34985246chr10:35360267ENST00000374794-2211151_1174741245Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34985246chr10:35360267ENST00000374794-2211201_1224741245Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34985246chr10:35360267ENST00000374794-2211280_1301741245Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34985246chr10:35360267ENST00000545260-2231049_1077741267Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34985246chr10:35360267ENST00000545260-2231151_1174741267Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34985246chr10:35360267ENST00000545260-2231201_1224741267Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34985246chr10:35360267ENST00000545260-2231280_1301741267Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34985246chr10:35360267ENST00000545693-2241049_1077741341Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34985246chr10:35360267ENST00000545693-2241151_1174741341Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34985246chr10:35360267ENST00000545693-2241201_1224741341Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34985246chr10:35360267ENST00000545693-2241280_1301741341Coiled coilOntology_term=ECO:0000255
HgenePARD3chr10:34985246chr10:35360267ENST00000340077-221984_1042741032Compositional biasNote=Lys-rich
HgenePARD3chr10:34985246chr10:35360267ENST00000346874-224984_1042741320Compositional biasNote=Lys-rich
HgenePARD3chr10:34985246chr10:35360267ENST00000350537-224984_1042741311Compositional biasNote=Lys-rich
HgenePARD3chr10:34985246chr10:35360267ENST00000374776-220984_104274989Compositional biasNote=Lys-rich
HgenePARD3chr10:34985246chr10:35360267ENST00000374788-225984_1042741354Compositional biasNote=Lys-rich
HgenePARD3chr10:34985246chr10:35360267ENST00000374789-225984_1042741357Compositional biasNote=Lys-rich
HgenePARD3chr10:34985246chr10:35360267ENST00000374794-221984_1042741245Compositional biasNote=Lys-rich
HgenePARD3chr10:34985246chr10:35360267ENST00000545260-223984_1042741267Compositional biasNote=Lys-rich
HgenePARD3chr10:34985246chr10:35360267ENST00000545693-224984_1042741341Compositional biasNote=Lys-rich
HgenePARD3chr10:34985246chr10:35360267ENST00000340077-221271_359741032DomainPDZ 1
HgenePARD3chr10:34985246chr10:35360267ENST00000340077-221461_546741032DomainPDZ 2
HgenePARD3chr10:34985246chr10:35360267ENST00000340077-221590_677741032DomainPDZ 3
HgenePARD3chr10:34985246chr10:35360267ENST00000346874-224271_359741320DomainPDZ 1
HgenePARD3chr10:34985246chr10:35360267ENST00000346874-224461_546741320DomainPDZ 2
HgenePARD3chr10:34985246chr10:35360267ENST00000346874-224590_677741320DomainPDZ 3
HgenePARD3chr10:34985246chr10:35360267ENST00000350537-224271_359741311DomainPDZ 1
HgenePARD3chr10:34985246chr10:35360267ENST00000350537-224461_546741311DomainPDZ 2
HgenePARD3chr10:34985246chr10:35360267ENST00000350537-224590_677741311DomainPDZ 3
HgenePARD3chr10:34985246chr10:35360267ENST00000374776-220271_35974989DomainPDZ 1
HgenePARD3chr10:34985246chr10:35360267ENST00000374776-220461_54674989DomainPDZ 2
HgenePARD3chr10:34985246chr10:35360267ENST00000374776-220590_67774989DomainPDZ 3
HgenePARD3chr10:34985246chr10:35360267ENST00000374788-225271_359741354DomainPDZ 1
HgenePARD3chr10:34985246chr10:35360267ENST00000374788-225461_546741354DomainPDZ 2
HgenePARD3chr10:34985246chr10:35360267ENST00000374788-225590_677741354DomainPDZ 3
HgenePARD3chr10:34985246chr10:35360267ENST00000374789-225271_359741357DomainPDZ 1
HgenePARD3chr10:34985246chr10:35360267ENST00000374789-225461_546741357DomainPDZ 2
HgenePARD3chr10:34985246chr10:35360267ENST00000374789-225590_677741357DomainPDZ 3
HgenePARD3chr10:34985246chr10:35360267ENST00000374794-221271_359741245DomainPDZ 1
HgenePARD3chr10:34985246chr10:35360267ENST00000374794-221461_546741245DomainPDZ 2
HgenePARD3chr10:34985246chr10:35360267ENST00000374794-221590_677741245DomainPDZ 3
HgenePARD3chr10:34985246chr10:35360267ENST00000545260-223271_359741267DomainPDZ 1
HgenePARD3chr10:34985246chr10:35360267ENST00000545260-223461_546741267DomainPDZ 2
HgenePARD3chr10:34985246chr10:35360267ENST00000545260-223590_677741267DomainPDZ 3
HgenePARD3chr10:34985246chr10:35360267ENST00000545693-224271_359741341DomainPDZ 1
HgenePARD3chr10:34985246chr10:35360267ENST00000545693-224461_546741341DomainPDZ 2
HgenePARD3chr10:34985246chr10:35360267ENST00000545693-224590_677741341DomainPDZ 3


Top

FusionGeneSequence for PARD3_CUL2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_PARD3_ENST00000545260_chr10_34985246_-_CUL2_ENST00000374746_chr10_35360267_-_74aa

>In-frame_PARD3_ENST00000545693_chr10_34985246_-_CUL2_ENST00000374746_chr10_35360267_-_74aa

>In-frame_PARD3_ENST00000350537_chr10_34985246_-_CUL2_ENST00000374746_chr10_35360267_-_74aa

>In-frame_PARD3_ENST00000346874_chr10_34985246_-_CUL2_ENST00000374746_chr10_35360267_-_74aa

>In-frame_PARD3_ENST00000374789_chr10_34985246_-_CUL2_ENST00000374746_chr10_35360267_-_74aa

>In-frame_PARD3_ENST00000374790_chr10_34985246_-_CUL2_ENST00000374746_chr10_35360267_-_74aa

>In-frame_PARD3_ENST00000374794_chr10_34985246_-_CUL2_ENST00000374746_chr10_35360267_-_74aa

>In-frame_PARD3_ENST00000374788_chr10_34985246_-_CUL2_ENST00000374746_chr10_35360267_-_74aa

>In-frame_PARD3_ENST00000374776_chr10_34985246_-_CUL2_ENST00000374746_chr10_35360267_-_74aa

>In-frame_PARD3_ENST00000340077_chr10_34985246_-_CUL2_ENST00000374746_chr10_35360267_-_74aa

>In-frame_PARD3_ENST00000374773_chr10_34985246_-_CUL2_ENST00000374746_chr10_35360267_-_74aa


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_PARD3_ENST00000545260_chr10_34985246_-_CUL2_ENST00000374746_chr10_35360267_-_222nt
ATGAAAGTGACCGTGTGCTTCGGACGGACCCGGGTGGTCGTGCCGTGCGGGGACGGCCACATGAAAGTTTTCAGCCTCATCCAGCAGGCG
GTGACCCGCTACCGGAAGGCCATCGCCAAGGATCCAAACTACTGGATACAGGTGCATCGCTTGGAACATGGAGATGGAGGAATACTAGAC

>In-frame_PARD3_ENST00000545693_chr10_34985246_-_CUL2_ENST00000374746_chr10_35360267_-_222nt
ATGAAAGTGACCGTGTGCTTCGGACGGACCCGGGTGGTCGTGCCGTGCGGGGACGGCCACATGAAAGTTTTCAGCCTCATCCAGCAGGCG
GTGACCCGCTACCGGAAGGCCATCGCCAAGGATCCAAACTACTGGATACAGGTGCATCGCTTGGAACATGGAGATGGAGGAATACTAGAC

>In-frame_PARD3_ENST00000350537_chr10_34985246_-_CUL2_ENST00000374746_chr10_35360267_-_222nt
ATGAAAGTGACCGTGTGCTTCGGACGGACCCGGGTGGTCGTGCCGTGCGGGGACGGCCACATGAAAGTTTTCAGCCTCATCCAGCAGGCG
GTGACCCGCTACCGGAAGGCCATCGCCAAGGATCCAAACTACTGGATACAGGTGCATCGCTTGGAACATGGAGATGGAGGAATACTAGAC

>In-frame_PARD3_ENST00000346874_chr10_34985246_-_CUL2_ENST00000374746_chr10_35360267_-_222nt
ATGAAAGTGACCGTGTGCTTCGGACGGACCCGGGTGGTCGTGCCGTGCGGGGACGGCCACATGAAAGTTTTCAGCCTCATCCAGCAGGCG
GTGACCCGCTACCGGAAGGCCATCGCCAAGGATCCAAACTACTGGATACAGGTGCATCGCTTGGAACATGGAGATGGAGGAATACTAGAC

>In-frame_PARD3_ENST00000374789_chr10_34985246_-_CUL2_ENST00000374746_chr10_35360267_-_222nt
ATGAAAGTGACCGTGTGCTTCGGACGGACCCGGGTGGTCGTGCCGTGCGGGGACGGCCACATGAAAGTTTTCAGCCTCATCCAGCAGGCG
GTGACCCGCTACCGGAAGGCCATCGCCAAGGATCCAAACTACTGGATACAGGTGCATCGCTTGGAACATGGAGATGGAGGAATACTAGAC

>In-frame_PARD3_ENST00000374790_chr10_34985246_-_CUL2_ENST00000374746_chr10_35360267_-_222nt
ATGAAAGTGACCGTGTGCTTCGGACGGACCCGGGTGGTCGTGCCGTGCGGGGACGGCCACATGAAAGTTTTCAGCCTCATCCAGCAGGCG
GTGACCCGCTACCGGAAGGCCATCGCCAAGGATCCAAACTACTGGATACAGGTGCATCGCTTGGAACATGGAGATGGAGGAATACTAGAC

>In-frame_PARD3_ENST00000374794_chr10_34985246_-_CUL2_ENST00000374746_chr10_35360267_-_222nt
ATGAAAGTGACCGTGTGCTTCGGACGGACCCGGGTGGTCGTGCCGTGCGGGGACGGCCACATGAAAGTTTTCAGCCTCATCCAGCAGGCG
GTGACCCGCTACCGGAAGGCCATCGCCAAGGATCCAAACTACTGGATACAGGTGCATCGCTTGGAACATGGAGATGGAGGAATACTAGAC

>In-frame_PARD3_ENST00000374788_chr10_34985246_-_CUL2_ENST00000374746_chr10_35360267_-_222nt
ATGAAAGTGACCGTGTGCTTCGGACGGACCCGGGTGGTCGTGCCGTGCGGGGACGGCCACATGAAAGTTTTCAGCCTCATCCAGCAGGCG
GTGACCCGCTACCGGAAGGCCATCGCCAAGGATCCAAACTACTGGATACAGGTGCATCGCTTGGAACATGGAGATGGAGGAATACTAGAC

>In-frame_PARD3_ENST00000374776_chr10_34985246_-_CUL2_ENST00000374746_chr10_35360267_-_222nt
ATGAAAGTGACCGTGTGCTTCGGACGGACCCGGGTGGTCGTGCCGTGCGGGGACGGCCACATGAAAGTTTTCAGCCTCATCCAGCAGGCG
GTGACCCGCTACCGGAAGGCCATCGCCAAGGATCCAAACTACTGGATACAGGTGCATCGCTTGGAACATGGAGATGGAGGAATACTAGAC

>In-frame_PARD3_ENST00000340077_chr10_34985246_-_CUL2_ENST00000374746_chr10_35360267_-_222nt
ATGAAAGTGACCGTGTGCTTCGGACGGACCCGGGTGGTCGTGCCGTGCGGGGACGGCCACATGAAAGTTTTCAGCCTCATCCAGCAGGCG
GTGACCCGCTACCGGAAGGCCATCGCCAAGGATCCAAACTACTGGATACAGGTGCATCGCTTGGAACATGGAGATGGAGGAATACTAGAC

>In-frame_PARD3_ENST00000374773_chr10_34985246_-_CUL2_ENST00000374746_chr10_35360267_-_222nt
ATGAAAGTGACCGTGTGCTTCGGACGGACCCGGGTGGTCGTGCCGTGCGGGGACGGCCACATGAAAGTTTTCAGCCTCATCCAGCAGGCG
GTGACCCGCTACCGGAAGGCCATCGCCAAGGATCCAAACTACTGGATACAGGTGCATCGCTTGGAACATGGAGATGGAGGAATACTAGAC


* Fusion transcript sequences (Full-length transcript).
>In-frame_PARD3_ENST00000545260_chr10_34985246_-_CUL2_ENST00000374746_chr10_35360267_-_4455nt
CCCAGCGGCCCCGAGCGAGCGCCAGCGCCACACAGCCCCGGGCAGCCGCCGGCGAGCGCGCCGCGACGCCGAACAGGTGGCCGGAGGCTG
CGGGCGCCGCGGCGGGGAGAGGCGAGGCAAGCCCCGGGCGAAGCGAGGCGAGGCGAGGGCGGCCGGGCCGGGCATGCGAGCTGAGCGGCC
CCCCGGCGTCGCCGCCGCCTGCCCGCGCCCCTAGCCGCCCGCGCGCCCGAGTCCCCAGCGGCTCCTCCGCGCCCAGCGTCCTCGGTCCCG
GCCTCGGCTGCTCCGGCTGCGCTCGGCGAGGGGCGCGGGCCCGCCCGCGGCGGCGGCGGCATGAAAGTGACCGTGTGCTTCGGACGGACC
CGGGTGGTCGTGCCGTGCGGGGACGGCCACATGAAAGTTTTCAGCCTCATCCAGCAGGCGGTGACCCGCTACCGGAAGGCCATCGCCAAG
GATCCAAACTACTGGATACAGGTGCATCGCTTGGAACATGGAGATGGAGGAATACTAGACCTTGATGACATTCTTTGTGATGTAGCAGAC
GATAAAGACAGAATTTCAACACTACACTTGCACAATGTCTTTGAAACCAAGAGTAGTAGATTTTGATGAAACATGGAACAAACTTTTGAC
GACAATAAAAGCCGTGGTCATGTTGGAATACGTCGAAAGAGCAACATGGAATGACCGTTTCTCAGATATCTATGCTTTATGTGTGGCCTA
TCCTGAACCCCTTGGAGAAAGACTTTATACAGAAACTAAGATTTTTTTGGAAAATCATGTTCGGCATTTGCATAAGAGAGTTTTGGAGTC
AGAAGAACAAGTACTTGTTATGTATCATAGGTACTGGGAAGAATACAGCAAGGGTGCAGACTATATGGACTGCTTATATAGGTATCTCAA
CACCCAGTTTATTAAAAAGAATAAATTAACAGAAGCGGACCTTCAGTATGGCTATGGTGGTGTAGATATGAATGAACCACTTATGGAAAT
AGGAGAGCTAGCATTGGATATGTGGAGGAAATTGATGGTTGAACCACTTCAGGCCATCCTTATCCGAATGCTGCTCCGAGAAATCAAAAA
TGATCGTGGTGGAGAAGACCCAAACCAGAAAGTAATCCATGGGGTTATTAACTCCTTTGTTCATGTTGAACAGTATAAGAAAAAATTCCC
CTTAAAGTTTTATCAGGAAATTTTTGAGTCTCCCTTTCTGACTGAAACAGGAGAGTATTACAAACAAGAAGCTTCAAATTTATTACAAGA
ATCAAACTGCTCACAGTATATGGAAAAGGTTCTAGGTAGATTAAAAGATGAAGAAATTCGATGTCGAAAATACCTACATCCAAGTTCATA
TACTAAGGTGATTCATGAATGTCAACAACGAATGGTAGCAGACCACTTACAGTTTTTACATGCAGAATGTCATAATATAATTCGACAAGA
GAAAAAAAATGACATGGCAAATATGTACGTCTTACTCCGTGCTGTGTCCACTGGTTTACCTCATATGATTCAGGAGCTGCAAAACCACAT
CCATGATGAGGGCCTTCGAGCAACCAGCAACCTTACTCAGGAAAACATGCCAACACTATTTGTGGAGTCAGTTTTGGAAGTGCATGGTAA
ATTTGTTCAGCTTATCAACACTGTTTTGAATGGTGATCAGCATTTTATGAGTGCGTTGGATAAGGCCCTTACGTCAGTTGTAAATTACAG
AGAACCTAAGTCTGTTTGCAAAGCACCTGAACTGCTTGCTAAGTACTGTGACAACTTACTGAAGAAGTCAGCGAAAGGGATGACAGAGAA
TGAAGTGGAAGACAGGCTCACGAGCTTCATCACAGTGTTCAAATACATTGATGACAAGGACGTCTTTCAAAAGTTCTACGCAAGAATGCT
GGCAAAACGTTTAATTCATGGGTTATCCATGTCTATGGACTCTGAAGAAGCCATGATCAACAAATTAAAGCAAGCCTGTGGTTATGAGTT
TACCAGCAAGCTACATCGGATGTATACAGATATGAGTGTCAGCGCTGATCTCAACAATAAGTTCAACAATTTTATCAAAAACCAAGACAC
AGTAATAGATTTGGGAATTAGTTTTCAAATATATGTTCTACAGGCTGGTGCGTGGCCTCTTACTCAGGCTCCTTCATCTACGTTTGCAAT
TCCCCAGGAATTAGAAAAAAGTGTACAGATGTTTGAATTATTTTATAGCCAACATTTCAGTGGAAGGAAACTTACATGGTTACATTATCT
GTGTACAGGTGAAGTTAAAATGAACTATTTGGGCAAACCATATGTAGCCATGGTTACAACATACCAAATGGCAGTTCTTCTTGCCTTTAA
CAACAGTGAAACTGTCAGTTATAAAGAGCTTCAGGACAGCACTCAGATGAATGAAAAGGAACTGACAAAAACAATCAAATCATTACTTGA
TGTGAAAATGATTAACCATGATTCAGAAAAGGAAGATATTGATGCAGAATCTTCGTTTTCATTAAATATGAACTTTAGCAGTAAAAGAAC
AAAATTTAAAATTACTACATCAATGCAGAAAGACACACCACAAGTGATTAGCCAGTCAAGAGCTAGGTTTAATCCCAGTATCAGCATGAT
TAAGAAGTGTATTGAAGTTCTGATAGACAAACAATACATAGAACGCAGCCAGGCGTCGGCAGATGAATACAGCTACGTCGCGTGATGTCG
CTCTCCTCCAGCGTGGTGTGAGAAGATCATTGCCATCACCATTTGGTGTGTTCCTGTGGGAAAAAGCAGGACTGTGCCTCCATAATTTGG
TCATTTGGCAGCCCCTGTTTTCTGCTGTTTACAACATCACCAGTGCCACGTCATGAGCGTCAAAGAAAATGCCTAGAGATATTTCAAGCT
CATGTCATTATGACATTTCTTAAAACTTTATTAAAAGAATGAGTGAAGTATTGCTGAAAAGTGGAAATTCGGTTGGGTACCATGCTTTTT
CTCCCCTTCACGTTTGCAGTTGATGTGTCTTTTTTTTTTTTTTTAATGTATCTTAAAGGACATAAAATTTAAAAACTTAAATATTGTAAT
ATGACAGATAACCTAATAATTGTATCTACATTAAAATGACAAACATGATACTGCTGCTTGTCAAATAAAAAAAAAATAAAGAAATAGAAT
GCCTTTTTTATGTGGATGGAGTATCAGGTTGACCACAAAATATATTGACTCAAAGCAGCTAATGCATCTTTAGTTGCGTTTTTATCTGAA
TGGTTTAATTCACTTGTACTCCTATTTAAATCCTACATGAAAAATGTCTAGATTATTGTTCTTGACTGCATAGGACTGCATTCAGCATAA
AGAATGCTTTATTTTTATGGATTAGATATATTGGATCTAAACATTTTGAATCTTGAAGATGTAATTCCATCAGCAGTTTCTGGTGGTGTG
CTACTCCACAGACATCGCAGAGTGTGAGCAGGATGCTTGGTGACCTCAAGTCTGGCACAGAGAGAGCTTTTCATTCAAAAGTTGTCTTTC
TTCGGTTGCATAATCCATTAATTCTAGCATAGACTAGTACCCTAGCTCTGTGGCCTTCCCTGAGTCTTAGGAAATCTATGATACCAACAT
ATTCCTTCTATATGCCTCCCCTACCTGTTACCCTTACAACCCTCCTCCAACAGTTTAGATACTAGAGTCACTCTCATCAATCACAGATGT
GCTTAGCAATGCATAACCTAAATACTTTTTTAAAAAAGAAAATTGTACATTGTACTGGGTGCCACATATATAAATCCCATTATTTTGTTT
ATTTTATATATATATATATATATAATATATATATATATATATCTCAACAGCAGTGTTAAGAGTACTGCGATCTATTATCATATTTATTGT
CTATCCACACCATCACCACCACCACCACACCCCTCCTCCCTCAACATACAATTTTTCTTTATTTTAAAAAAAATAAGAGACGGGGTTTCG
CCATGTTTCCCAGGCTAGTCTGGAACTTCTGGCCTCAAGCAATCCTATCTCTGTCTCCCAAAGTGCTGGGATTACAAGCATGAGCCACTG
CATCCATCCAACACAAAATTTTTAAAATCGGAATATTTTAAAGCAAATCACACAAATTATTTCACTTATAATACTTCAGTAAGGCCTTTA
AAAAATCCACAGTGATATTATTACTCCTAACAAAAACAATAATTACTTAGTATCATCTAATATGTGGTTCATATTTAAATTTGTTGTTTT
GAGATGGGTCTTACAATTGGTTTATTCAATTGCATTTTTTCTAACTCGTGTCTCAAGTGTTTTAAAAATCTACTGAACTTATAATGACTT
ATATAATGTATTTCTCATTTTACCTTTCTTCCAAAAGAGGAAATAATGGCAAACCATATAATATTGTACATTCACTGTCAAAAAGCAAAC

>In-frame_PARD3_ENST00000545693_chr10_34985246_-_CUL2_ENST00000374746_chr10_35360267_-_4455nt
CCCAGCGGCCCCGAGCGAGCGCCAGCGCCACACAGCCCCGGGCAGCCGCCGGCGAGCGCGCCGCGACGCCGAACAGGTGGCCGGAGGCTG
CGGGCGCCGCGGCGGGGAGAGGCGAGGCAAGCCCCGGGCGAAGCGAGGCGAGGCGAGGGCGGCCGGGCCGGGCATGCGAGCTGAGCGGCC
CCCCGGCGTCGCCGCCGCCTGCCCGCGCCCCTAGCCGCCCGCGCGCCCGAGTCCCCAGCGGCTCCTCCGCGCCCAGCGTCCTCGGTCCCG
GCCTCGGCTGCTCCGGCTGCGCTCGGCGAGGGGCGCGGGCCCGCCCGCGGCGGCGGCGGCATGAAAGTGACCGTGTGCTTCGGACGGACC
CGGGTGGTCGTGCCGTGCGGGGACGGCCACATGAAAGTTTTCAGCCTCATCCAGCAGGCGGTGACCCGCTACCGGAAGGCCATCGCCAAG
GATCCAAACTACTGGATACAGGTGCATCGCTTGGAACATGGAGATGGAGGAATACTAGACCTTGATGACATTCTTTGTGATGTAGCAGAC
GATAAAGACAGAATTTCAACACTACACTTGCACAATGTCTTTGAAACCAAGAGTAGTAGATTTTGATGAAACATGGAACAAACTTTTGAC
GACAATAAAAGCCGTGGTCATGTTGGAATACGTCGAAAGAGCAACATGGAATGACCGTTTCTCAGATATCTATGCTTTATGTGTGGCCTA
TCCTGAACCCCTTGGAGAAAGACTTTATACAGAAACTAAGATTTTTTTGGAAAATCATGTTCGGCATTTGCATAAGAGAGTTTTGGAGTC
AGAAGAACAAGTACTTGTTATGTATCATAGGTACTGGGAAGAATACAGCAAGGGTGCAGACTATATGGACTGCTTATATAGGTATCTCAA
CACCCAGTTTATTAAAAAGAATAAATTAACAGAAGCGGACCTTCAGTATGGCTATGGTGGTGTAGATATGAATGAACCACTTATGGAAAT
AGGAGAGCTAGCATTGGATATGTGGAGGAAATTGATGGTTGAACCACTTCAGGCCATCCTTATCCGAATGCTGCTCCGAGAAATCAAAAA
TGATCGTGGTGGAGAAGACCCAAACCAGAAAGTAATCCATGGGGTTATTAACTCCTTTGTTCATGTTGAACAGTATAAGAAAAAATTCCC
CTTAAAGTTTTATCAGGAAATTTTTGAGTCTCCCTTTCTGACTGAAACAGGAGAGTATTACAAACAAGAAGCTTCAAATTTATTACAAGA
ATCAAACTGCTCACAGTATATGGAAAAGGTTCTAGGTAGATTAAAAGATGAAGAAATTCGATGTCGAAAATACCTACATCCAAGTTCATA
TACTAAGGTGATTCATGAATGTCAACAACGAATGGTAGCAGACCACTTACAGTTTTTACATGCAGAATGTCATAATATAATTCGACAAGA
GAAAAAAAATGACATGGCAAATATGTACGTCTTACTCCGTGCTGTGTCCACTGGTTTACCTCATATGATTCAGGAGCTGCAAAACCACAT
CCATGATGAGGGCCTTCGAGCAACCAGCAACCTTACTCAGGAAAACATGCCAACACTATTTGTGGAGTCAGTTTTGGAAGTGCATGGTAA
ATTTGTTCAGCTTATCAACACTGTTTTGAATGGTGATCAGCATTTTATGAGTGCGTTGGATAAGGCCCTTACGTCAGTTGTAAATTACAG
AGAACCTAAGTCTGTTTGCAAAGCACCTGAACTGCTTGCTAAGTACTGTGACAACTTACTGAAGAAGTCAGCGAAAGGGATGACAGAGAA
TGAAGTGGAAGACAGGCTCACGAGCTTCATCACAGTGTTCAAATACATTGATGACAAGGACGTCTTTCAAAAGTTCTACGCAAGAATGCT
GGCAAAACGTTTAATTCATGGGTTATCCATGTCTATGGACTCTGAAGAAGCCATGATCAACAAATTAAAGCAAGCCTGTGGTTATGAGTT
TACCAGCAAGCTACATCGGATGTATACAGATATGAGTGTCAGCGCTGATCTCAACAATAAGTTCAACAATTTTATCAAAAACCAAGACAC
AGTAATAGATTTGGGAATTAGTTTTCAAATATATGTTCTACAGGCTGGTGCGTGGCCTCTTACTCAGGCTCCTTCATCTACGTTTGCAAT
TCCCCAGGAATTAGAAAAAAGTGTACAGATGTTTGAATTATTTTATAGCCAACATTTCAGTGGAAGGAAACTTACATGGTTACATTATCT
GTGTACAGGTGAAGTTAAAATGAACTATTTGGGCAAACCATATGTAGCCATGGTTACAACATACCAAATGGCAGTTCTTCTTGCCTTTAA
CAACAGTGAAACTGTCAGTTATAAAGAGCTTCAGGACAGCACTCAGATGAATGAAAAGGAACTGACAAAAACAATCAAATCATTACTTGA
TGTGAAAATGATTAACCATGATTCAGAAAAGGAAGATATTGATGCAGAATCTTCGTTTTCATTAAATATGAACTTTAGCAGTAAAAGAAC
AAAATTTAAAATTACTACATCAATGCAGAAAGACACACCACAAGTGATTAGCCAGTCAAGAGCTAGGTTTAATCCCAGTATCAGCATGAT
TAAGAAGTGTATTGAAGTTCTGATAGACAAACAATACATAGAACGCAGCCAGGCGTCGGCAGATGAATACAGCTACGTCGCGTGATGTCG
CTCTCCTCCAGCGTGGTGTGAGAAGATCATTGCCATCACCATTTGGTGTGTTCCTGTGGGAAAAAGCAGGACTGTGCCTCCATAATTTGG
TCATTTGGCAGCCCCTGTTTTCTGCTGTTTACAACATCACCAGTGCCACGTCATGAGCGTCAAAGAAAATGCCTAGAGATATTTCAAGCT
CATGTCATTATGACATTTCTTAAAACTTTATTAAAAGAATGAGTGAAGTATTGCTGAAAAGTGGAAATTCGGTTGGGTACCATGCTTTTT
CTCCCCTTCACGTTTGCAGTTGATGTGTCTTTTTTTTTTTTTTTAATGTATCTTAAAGGACATAAAATTTAAAAACTTAAATATTGTAAT
ATGACAGATAACCTAATAATTGTATCTACATTAAAATGACAAACATGATACTGCTGCTTGTCAAATAAAAAAAAAATAAAGAAATAGAAT
GCCTTTTTTATGTGGATGGAGTATCAGGTTGACCACAAAATATATTGACTCAAAGCAGCTAATGCATCTTTAGTTGCGTTTTTATCTGAA
TGGTTTAATTCACTTGTACTCCTATTTAAATCCTACATGAAAAATGTCTAGATTATTGTTCTTGACTGCATAGGACTGCATTCAGCATAA
AGAATGCTTTATTTTTATGGATTAGATATATTGGATCTAAACATTTTGAATCTTGAAGATGTAATTCCATCAGCAGTTTCTGGTGGTGTG
CTACTCCACAGACATCGCAGAGTGTGAGCAGGATGCTTGGTGACCTCAAGTCTGGCACAGAGAGAGCTTTTCATTCAAAAGTTGTCTTTC
TTCGGTTGCATAATCCATTAATTCTAGCATAGACTAGTACCCTAGCTCTGTGGCCTTCCCTGAGTCTTAGGAAATCTATGATACCAACAT
ATTCCTTCTATATGCCTCCCCTACCTGTTACCCTTACAACCCTCCTCCAACAGTTTAGATACTAGAGTCACTCTCATCAATCACAGATGT
GCTTAGCAATGCATAACCTAAATACTTTTTTAAAAAAGAAAATTGTACATTGTACTGGGTGCCACATATATAAATCCCATTATTTTGTTT
ATTTTATATATATATATATATATAATATATATATATATATATCTCAACAGCAGTGTTAAGAGTACTGCGATCTATTATCATATTTATTGT
CTATCCACACCATCACCACCACCACCACACCCCTCCTCCCTCAACATACAATTTTTCTTTATTTTAAAAAAAATAAGAGACGGGGTTTCG
CCATGTTTCCCAGGCTAGTCTGGAACTTCTGGCCTCAAGCAATCCTATCTCTGTCTCCCAAAGTGCTGGGATTACAAGCATGAGCCACTG
CATCCATCCAACACAAAATTTTTAAAATCGGAATATTTTAAAGCAAATCACACAAATTATTTCACTTATAATACTTCAGTAAGGCCTTTA
AAAAATCCACAGTGATATTATTACTCCTAACAAAAACAATAATTACTTAGTATCATCTAATATGTGGTTCATATTTAAATTTGTTGTTTT
GAGATGGGTCTTACAATTGGTTTATTCAATTGCATTTTTTCTAACTCGTGTCTCAAGTGTTTTAAAAATCTACTGAACTTATAATGACTT
ATATAATGTATTTCTCATTTTACCTTTCTTCCAAAAGAGGAAATAATGGCAAACCATATAATATTGTACATTCACTGTCAAAAAGCAAAC

>In-frame_PARD3_ENST00000350537_chr10_34985246_-_CUL2_ENST00000374746_chr10_35360267_-_4451nt
GCGGCCCCGAGCGAGCGCCAGCGCCACACAGCCCCGGGCAGCCGCCGGCGAGCGCGCCGCGACGCCGAACAGGTGGCCGGAGGCTGCGGG
CGCCGCGGCGGGGAGAGGCGAGGCAAGCCCCGGGCGAAGCGAGGCGAGGCGAGGGCGGCCGGGCCGGGCATGCGAGCTGAGCGGCCCCCC
GGCGTCGCCGCCGCCTGCCCGCGCCCCTAGCCGCCCGCGCGCCCGAGTCCCCAGCGGCTCCTCCGCGCCCAGCGTCCTCGGTCCCGGCCT
CGGCTGCTCCGGCTGCGCTCGGCGAGGGGCGCGGGCCCGCCCGCGGCGGCGGCGGCATGAAAGTGACCGTGTGCTTCGGACGGACCCGGG
TGGTCGTGCCGTGCGGGGACGGCCACATGAAAGTTTTCAGCCTCATCCAGCAGGCGGTGACCCGCTACCGGAAGGCCATCGCCAAGGATC
CAAACTACTGGATACAGGTGCATCGCTTGGAACATGGAGATGGAGGAATACTAGACCTTGATGACATTCTTTGTGATGTAGCAGACGATA
AAGACAGAATTTCAACACTACACTTGCACAATGTCTTTGAAACCAAGAGTAGTAGATTTTGATGAAACATGGAACAAACTTTTGACGACA
ATAAAAGCCGTGGTCATGTTGGAATACGTCGAAAGAGCAACATGGAATGACCGTTTCTCAGATATCTATGCTTTATGTGTGGCCTATCCT
GAACCCCTTGGAGAAAGACTTTATACAGAAACTAAGATTTTTTTGGAAAATCATGTTCGGCATTTGCATAAGAGAGTTTTGGAGTCAGAA
GAACAAGTACTTGTTATGTATCATAGGTACTGGGAAGAATACAGCAAGGGTGCAGACTATATGGACTGCTTATATAGGTATCTCAACACC
CAGTTTATTAAAAAGAATAAATTAACAGAAGCGGACCTTCAGTATGGCTATGGTGGTGTAGATATGAATGAACCACTTATGGAAATAGGA
GAGCTAGCATTGGATATGTGGAGGAAATTGATGGTTGAACCACTTCAGGCCATCCTTATCCGAATGCTGCTCCGAGAAATCAAAAATGAT
CGTGGTGGAGAAGACCCAAACCAGAAAGTAATCCATGGGGTTATTAACTCCTTTGTTCATGTTGAACAGTATAAGAAAAAATTCCCCTTA
AAGTTTTATCAGGAAATTTTTGAGTCTCCCTTTCTGACTGAAACAGGAGAGTATTACAAACAAGAAGCTTCAAATTTATTACAAGAATCA
AACTGCTCACAGTATATGGAAAAGGTTCTAGGTAGATTAAAAGATGAAGAAATTCGATGTCGAAAATACCTACATCCAAGTTCATATACT
AAGGTGATTCATGAATGTCAACAACGAATGGTAGCAGACCACTTACAGTTTTTACATGCAGAATGTCATAATATAATTCGACAAGAGAAA
AAAAATGACATGGCAAATATGTACGTCTTACTCCGTGCTGTGTCCACTGGTTTACCTCATATGATTCAGGAGCTGCAAAACCACATCCAT
GATGAGGGCCTTCGAGCAACCAGCAACCTTACTCAGGAAAACATGCCAACACTATTTGTGGAGTCAGTTTTGGAAGTGCATGGTAAATTT
GTTCAGCTTATCAACACTGTTTTGAATGGTGATCAGCATTTTATGAGTGCGTTGGATAAGGCCCTTACGTCAGTTGTAAATTACAGAGAA
CCTAAGTCTGTTTGCAAAGCACCTGAACTGCTTGCTAAGTACTGTGACAACTTACTGAAGAAGTCAGCGAAAGGGATGACAGAGAATGAA
GTGGAAGACAGGCTCACGAGCTTCATCACAGTGTTCAAATACATTGATGACAAGGACGTCTTTCAAAAGTTCTACGCAAGAATGCTGGCA
AAACGTTTAATTCATGGGTTATCCATGTCTATGGACTCTGAAGAAGCCATGATCAACAAATTAAAGCAAGCCTGTGGTTATGAGTTTACC
AGCAAGCTACATCGGATGTATACAGATATGAGTGTCAGCGCTGATCTCAACAATAAGTTCAACAATTTTATCAAAAACCAAGACACAGTA
ATAGATTTGGGAATTAGTTTTCAAATATATGTTCTACAGGCTGGTGCGTGGCCTCTTACTCAGGCTCCTTCATCTACGTTTGCAATTCCC
CAGGAATTAGAAAAAAGTGTACAGATGTTTGAATTATTTTATAGCCAACATTTCAGTGGAAGGAAACTTACATGGTTACATTATCTGTGT
ACAGGTGAAGTTAAAATGAACTATTTGGGCAAACCATATGTAGCCATGGTTACAACATACCAAATGGCAGTTCTTCTTGCCTTTAACAAC
AGTGAAACTGTCAGTTATAAAGAGCTTCAGGACAGCACTCAGATGAATGAAAAGGAACTGACAAAAACAATCAAATCATTACTTGATGTG
AAAATGATTAACCATGATTCAGAAAAGGAAGATATTGATGCAGAATCTTCGTTTTCATTAAATATGAACTTTAGCAGTAAAAGAACAAAA
TTTAAAATTACTACATCAATGCAGAAAGACACACCACAAGTGATTAGCCAGTCAAGAGCTAGGTTTAATCCCAGTATCAGCATGATTAAG
AAGTGTATTGAAGTTCTGATAGACAAACAATACATAGAACGCAGCCAGGCGTCGGCAGATGAATACAGCTACGTCGCGTGATGTCGCTCT
CCTCCAGCGTGGTGTGAGAAGATCATTGCCATCACCATTTGGTGTGTTCCTGTGGGAAAAAGCAGGACTGTGCCTCCATAATTTGGTCAT
TTGGCAGCCCCTGTTTTCTGCTGTTTACAACATCACCAGTGCCACGTCATGAGCGTCAAAGAAAATGCCTAGAGATATTTCAAGCTCATG
TCATTATGACATTTCTTAAAACTTTATTAAAAGAATGAGTGAAGTATTGCTGAAAAGTGGAAATTCGGTTGGGTACCATGCTTTTTCTCC
CCTTCACGTTTGCAGTTGATGTGTCTTTTTTTTTTTTTTTAATGTATCTTAAAGGACATAAAATTTAAAAACTTAAATATTGTAATATGA
CAGATAACCTAATAATTGTATCTACATTAAAATGACAAACATGATACTGCTGCTTGTCAAATAAAAAAAAAATAAAGAAATAGAATGCCT
TTTTTATGTGGATGGAGTATCAGGTTGACCACAAAATATATTGACTCAAAGCAGCTAATGCATCTTTAGTTGCGTTTTTATCTGAATGGT
TTAATTCACTTGTACTCCTATTTAAATCCTACATGAAAAATGTCTAGATTATTGTTCTTGACTGCATAGGACTGCATTCAGCATAAAGAA
TGCTTTATTTTTATGGATTAGATATATTGGATCTAAACATTTTGAATCTTGAAGATGTAATTCCATCAGCAGTTTCTGGTGGTGTGCTAC
TCCACAGACATCGCAGAGTGTGAGCAGGATGCTTGGTGACCTCAAGTCTGGCACAGAGAGAGCTTTTCATTCAAAAGTTGTCTTTCTTCG
GTTGCATAATCCATTAATTCTAGCATAGACTAGTACCCTAGCTCTGTGGCCTTCCCTGAGTCTTAGGAAATCTATGATACCAACATATTC
CTTCTATATGCCTCCCCTACCTGTTACCCTTACAACCCTCCTCCAACAGTTTAGATACTAGAGTCACTCTCATCAATCACAGATGTGCTT
AGCAATGCATAACCTAAATACTTTTTTAAAAAAGAAAATTGTACATTGTACTGGGTGCCACATATATAAATCCCATTATTTTGTTTATTT
TATATATATATATATATATAATATATATATATATATATCTCAACAGCAGTGTTAAGAGTACTGCGATCTATTATCATATTTATTGTCTAT
CCACACCATCACCACCACCACCACACCCCTCCTCCCTCAACATACAATTTTTCTTTATTTTAAAAAAAATAAGAGACGGGGTTTCGCCAT
GTTTCCCAGGCTAGTCTGGAACTTCTGGCCTCAAGCAATCCTATCTCTGTCTCCCAAAGTGCTGGGATTACAAGCATGAGCCACTGCATC
CATCCAACACAAAATTTTTAAAATCGGAATATTTTAAAGCAAATCACACAAATTATTTCACTTATAATACTTCAGTAAGGCCTTTAAAAA
ATCCACAGTGATATTATTACTCCTAACAAAAACAATAATTACTTAGTATCATCTAATATGTGGTTCATATTTAAATTTGTTGTTTTGAGA
TGGGTCTTACAATTGGTTTATTCAATTGCATTTTTTCTAACTCGTGTCTCAAGTGTTTTAAAAATCTACTGAACTTATAATGACTTATAT
AATGTATTTCTCATTTTACCTTTCTTCCAAAAGAGGAAATAATGGCAAACCATATAATATTGTACATTCACTGTCAAAAAGCAAACCCTT

>In-frame_PARD3_ENST00000346874_chr10_34985246_-_CUL2_ENST00000374746_chr10_35360267_-_4451nt
GCGGCCCCGAGCGAGCGCCAGCGCCACACAGCCCCGGGCAGCCGCCGGCGAGCGCGCCGCGACGCCGAACAGGTGGCCGGAGGCTGCGGG
CGCCGCGGCGGGGAGAGGCGAGGCAAGCCCCGGGCGAAGCGAGGCGAGGCGAGGGCGGCCGGGCCGGGCATGCGAGCTGAGCGGCCCCCC
GGCGTCGCCGCCGCCTGCCCGCGCCCCTAGCCGCCCGCGCGCCCGAGTCCCCAGCGGCTCCTCCGCGCCCAGCGTCCTCGGTCCCGGCCT
CGGCTGCTCCGGCTGCGCTCGGCGAGGGGCGCGGGCCCGCCCGCGGCGGCGGCGGCATGAAAGTGACCGTGTGCTTCGGACGGACCCGGG
TGGTCGTGCCGTGCGGGGACGGCCACATGAAAGTTTTCAGCCTCATCCAGCAGGCGGTGACCCGCTACCGGAAGGCCATCGCCAAGGATC
CAAACTACTGGATACAGGTGCATCGCTTGGAACATGGAGATGGAGGAATACTAGACCTTGATGACATTCTTTGTGATGTAGCAGACGATA
AAGACAGAATTTCAACACTACACTTGCACAATGTCTTTGAAACCAAGAGTAGTAGATTTTGATGAAACATGGAACAAACTTTTGACGACA
ATAAAAGCCGTGGTCATGTTGGAATACGTCGAAAGAGCAACATGGAATGACCGTTTCTCAGATATCTATGCTTTATGTGTGGCCTATCCT
GAACCCCTTGGAGAAAGACTTTATACAGAAACTAAGATTTTTTTGGAAAATCATGTTCGGCATTTGCATAAGAGAGTTTTGGAGTCAGAA
GAACAAGTACTTGTTATGTATCATAGGTACTGGGAAGAATACAGCAAGGGTGCAGACTATATGGACTGCTTATATAGGTATCTCAACACC
CAGTTTATTAAAAAGAATAAATTAACAGAAGCGGACCTTCAGTATGGCTATGGTGGTGTAGATATGAATGAACCACTTATGGAAATAGGA
GAGCTAGCATTGGATATGTGGAGGAAATTGATGGTTGAACCACTTCAGGCCATCCTTATCCGAATGCTGCTCCGAGAAATCAAAAATGAT
CGTGGTGGAGAAGACCCAAACCAGAAAGTAATCCATGGGGTTATTAACTCCTTTGTTCATGTTGAACAGTATAAGAAAAAATTCCCCTTA
AAGTTTTATCAGGAAATTTTTGAGTCTCCCTTTCTGACTGAAACAGGAGAGTATTACAAACAAGAAGCTTCAAATTTATTACAAGAATCA
AACTGCTCACAGTATATGGAAAAGGTTCTAGGTAGATTAAAAGATGAAGAAATTCGATGTCGAAAATACCTACATCCAAGTTCATATACT
AAGGTGATTCATGAATGTCAACAACGAATGGTAGCAGACCACTTACAGTTTTTACATGCAGAATGTCATAATATAATTCGACAAGAGAAA
AAAAATGACATGGCAAATATGTACGTCTTACTCCGTGCTGTGTCCACTGGTTTACCTCATATGATTCAGGAGCTGCAAAACCACATCCAT
GATGAGGGCCTTCGAGCAACCAGCAACCTTACTCAGGAAAACATGCCAACACTATTTGTGGAGTCAGTTTTGGAAGTGCATGGTAAATTT
GTTCAGCTTATCAACACTGTTTTGAATGGTGATCAGCATTTTATGAGTGCGTTGGATAAGGCCCTTACGTCAGTTGTAAATTACAGAGAA
CCTAAGTCTGTTTGCAAAGCACCTGAACTGCTTGCTAAGTACTGTGACAACTTACTGAAGAAGTCAGCGAAAGGGATGACAGAGAATGAA
GTGGAAGACAGGCTCACGAGCTTCATCACAGTGTTCAAATACATTGATGACAAGGACGTCTTTCAAAAGTTCTACGCAAGAATGCTGGCA
AAACGTTTAATTCATGGGTTATCCATGTCTATGGACTCTGAAGAAGCCATGATCAACAAATTAAAGCAAGCCTGTGGTTATGAGTTTACC
AGCAAGCTACATCGGATGTATACAGATATGAGTGTCAGCGCTGATCTCAACAATAAGTTCAACAATTTTATCAAAAACCAAGACACAGTA
ATAGATTTGGGAATTAGTTTTCAAATATATGTTCTACAGGCTGGTGCGTGGCCTCTTACTCAGGCTCCTTCATCTACGTTTGCAATTCCC
CAGGAATTAGAAAAAAGTGTACAGATGTTTGAATTATTTTATAGCCAACATTTCAGTGGAAGGAAACTTACATGGTTACATTATCTGTGT
ACAGGTGAAGTTAAAATGAACTATTTGGGCAAACCATATGTAGCCATGGTTACAACATACCAAATGGCAGTTCTTCTTGCCTTTAACAAC
AGTGAAACTGTCAGTTATAAAGAGCTTCAGGACAGCACTCAGATGAATGAAAAGGAACTGACAAAAACAATCAAATCATTACTTGATGTG
AAAATGATTAACCATGATTCAGAAAAGGAAGATATTGATGCAGAATCTTCGTTTTCATTAAATATGAACTTTAGCAGTAAAAGAACAAAA
TTTAAAATTACTACATCAATGCAGAAAGACACACCACAAGTGATTAGCCAGTCAAGAGCTAGGTTTAATCCCAGTATCAGCATGATTAAG
AAGTGTATTGAAGTTCTGATAGACAAACAATACATAGAACGCAGCCAGGCGTCGGCAGATGAATACAGCTACGTCGCGTGATGTCGCTCT
CCTCCAGCGTGGTGTGAGAAGATCATTGCCATCACCATTTGGTGTGTTCCTGTGGGAAAAAGCAGGACTGTGCCTCCATAATTTGGTCAT
TTGGCAGCCCCTGTTTTCTGCTGTTTACAACATCACCAGTGCCACGTCATGAGCGTCAAAGAAAATGCCTAGAGATATTTCAAGCTCATG
TCATTATGACATTTCTTAAAACTTTATTAAAAGAATGAGTGAAGTATTGCTGAAAAGTGGAAATTCGGTTGGGTACCATGCTTTTTCTCC
CCTTCACGTTTGCAGTTGATGTGTCTTTTTTTTTTTTTTTAATGTATCTTAAAGGACATAAAATTTAAAAACTTAAATATTGTAATATGA
CAGATAACCTAATAATTGTATCTACATTAAAATGACAAACATGATACTGCTGCTTGTCAAATAAAAAAAAAATAAAGAAATAGAATGCCT
TTTTTATGTGGATGGAGTATCAGGTTGACCACAAAATATATTGACTCAAAGCAGCTAATGCATCTTTAGTTGCGTTTTTATCTGAATGGT
TTAATTCACTTGTACTCCTATTTAAATCCTACATGAAAAATGTCTAGATTATTGTTCTTGACTGCATAGGACTGCATTCAGCATAAAGAA
TGCTTTATTTTTATGGATTAGATATATTGGATCTAAACATTTTGAATCTTGAAGATGTAATTCCATCAGCAGTTTCTGGTGGTGTGCTAC
TCCACAGACATCGCAGAGTGTGAGCAGGATGCTTGGTGACCTCAAGTCTGGCACAGAGAGAGCTTTTCATTCAAAAGTTGTCTTTCTTCG
GTTGCATAATCCATTAATTCTAGCATAGACTAGTACCCTAGCTCTGTGGCCTTCCCTGAGTCTTAGGAAATCTATGATACCAACATATTC
CTTCTATATGCCTCCCCTACCTGTTACCCTTACAACCCTCCTCCAACAGTTTAGATACTAGAGTCACTCTCATCAATCACAGATGTGCTT
AGCAATGCATAACCTAAATACTTTTTTAAAAAAGAAAATTGTACATTGTACTGGGTGCCACATATATAAATCCCATTATTTTGTTTATTT
TATATATATATATATATATAATATATATATATATATATCTCAACAGCAGTGTTAAGAGTACTGCGATCTATTATCATATTTATTGTCTAT
CCACACCATCACCACCACCACCACACCCCTCCTCCCTCAACATACAATTTTTCTTTATTTTAAAAAAAATAAGAGACGGGGTTTCGCCAT
GTTTCCCAGGCTAGTCTGGAACTTCTGGCCTCAAGCAATCCTATCTCTGTCTCCCAAAGTGCTGGGATTACAAGCATGAGCCACTGCATC
CATCCAACACAAAATTTTTAAAATCGGAATATTTTAAAGCAAATCACACAAATTATTTCACTTATAATACTTCAGTAAGGCCTTTAAAAA
ATCCACAGTGATATTATTACTCCTAACAAAAACAATAATTACTTAGTATCATCTAATATGTGGTTCATATTTAAATTTGTTGTTTTGAGA
TGGGTCTTACAATTGGTTTATTCAATTGCATTTTTTCTAACTCGTGTCTCAAGTGTTTTAAAAATCTACTGAACTTATAATGACTTATAT
AATGTATTTCTCATTTTACCTTTCTTCCAAAAGAGGAAATAATGGCAAACCATATAATATTGTACATTCACTGTCAAAAAGCAAACCCTT

>In-frame_PARD3_ENST00000374789_chr10_34985246_-_CUL2_ENST00000374746_chr10_35360267_-_4451nt
GCGGCCCCGAGCGAGCGCCAGCGCCACACAGCCCCGGGCAGCCGCCGGCGAGCGCGCCGCGACGCCGAACAGGTGGCCGGAGGCTGCGGG
CGCCGCGGCGGGGAGAGGCGAGGCAAGCCCCGGGCGAAGCGAGGCGAGGCGAGGGCGGCCGGGCCGGGCATGCGAGCTGAGCGGCCCCCC
GGCGTCGCCGCCGCCTGCCCGCGCCCCTAGCCGCCCGCGCGCCCGAGTCCCCAGCGGCTCCTCCGCGCCCAGCGTCCTCGGTCCCGGCCT
CGGCTGCTCCGGCTGCGCTCGGCGAGGGGCGCGGGCCCGCCCGCGGCGGCGGCGGCATGAAAGTGACCGTGTGCTTCGGACGGACCCGGG
TGGTCGTGCCGTGCGGGGACGGCCACATGAAAGTTTTCAGCCTCATCCAGCAGGCGGTGACCCGCTACCGGAAGGCCATCGCCAAGGATC
CAAACTACTGGATACAGGTGCATCGCTTGGAACATGGAGATGGAGGAATACTAGACCTTGATGACATTCTTTGTGATGTAGCAGACGATA
AAGACAGAATTTCAACACTACACTTGCACAATGTCTTTGAAACCAAGAGTAGTAGATTTTGATGAAACATGGAACAAACTTTTGACGACA
ATAAAAGCCGTGGTCATGTTGGAATACGTCGAAAGAGCAACATGGAATGACCGTTTCTCAGATATCTATGCTTTATGTGTGGCCTATCCT
GAACCCCTTGGAGAAAGACTTTATACAGAAACTAAGATTTTTTTGGAAAATCATGTTCGGCATTTGCATAAGAGAGTTTTGGAGTCAGAA
GAACAAGTACTTGTTATGTATCATAGGTACTGGGAAGAATACAGCAAGGGTGCAGACTATATGGACTGCTTATATAGGTATCTCAACACC
CAGTTTATTAAAAAGAATAAATTAACAGAAGCGGACCTTCAGTATGGCTATGGTGGTGTAGATATGAATGAACCACTTATGGAAATAGGA
GAGCTAGCATTGGATATGTGGAGGAAATTGATGGTTGAACCACTTCAGGCCATCCTTATCCGAATGCTGCTCCGAGAAATCAAAAATGAT
CGTGGTGGAGAAGACCCAAACCAGAAAGTAATCCATGGGGTTATTAACTCCTTTGTTCATGTTGAACAGTATAAGAAAAAATTCCCCTTA
AAGTTTTATCAGGAAATTTTTGAGTCTCCCTTTCTGACTGAAACAGGAGAGTATTACAAACAAGAAGCTTCAAATTTATTACAAGAATCA
AACTGCTCACAGTATATGGAAAAGGTTCTAGGTAGATTAAAAGATGAAGAAATTCGATGTCGAAAATACCTACATCCAAGTTCATATACT
AAGGTGATTCATGAATGTCAACAACGAATGGTAGCAGACCACTTACAGTTTTTACATGCAGAATGTCATAATATAATTCGACAAGAGAAA
AAAAATGACATGGCAAATATGTACGTCTTACTCCGTGCTGTGTCCACTGGTTTACCTCATATGATTCAGGAGCTGCAAAACCACATCCAT
GATGAGGGCCTTCGAGCAACCAGCAACCTTACTCAGGAAAACATGCCAACACTATTTGTGGAGTCAGTTTTGGAAGTGCATGGTAAATTT
GTTCAGCTTATCAACACTGTTTTGAATGGTGATCAGCATTTTATGAGTGCGTTGGATAAGGCCCTTACGTCAGTTGTAAATTACAGAGAA
CCTAAGTCTGTTTGCAAAGCACCTGAACTGCTTGCTAAGTACTGTGACAACTTACTGAAGAAGTCAGCGAAAGGGATGACAGAGAATGAA
GTGGAAGACAGGCTCACGAGCTTCATCACAGTGTTCAAATACATTGATGACAAGGACGTCTTTCAAAAGTTCTACGCAAGAATGCTGGCA
AAACGTTTAATTCATGGGTTATCCATGTCTATGGACTCTGAAGAAGCCATGATCAACAAATTAAAGCAAGCCTGTGGTTATGAGTTTACC
AGCAAGCTACATCGGATGTATACAGATATGAGTGTCAGCGCTGATCTCAACAATAAGTTCAACAATTTTATCAAAAACCAAGACACAGTA
ATAGATTTGGGAATTAGTTTTCAAATATATGTTCTACAGGCTGGTGCGTGGCCTCTTACTCAGGCTCCTTCATCTACGTTTGCAATTCCC
CAGGAATTAGAAAAAAGTGTACAGATGTTTGAATTATTTTATAGCCAACATTTCAGTGGAAGGAAACTTACATGGTTACATTATCTGTGT
ACAGGTGAAGTTAAAATGAACTATTTGGGCAAACCATATGTAGCCATGGTTACAACATACCAAATGGCAGTTCTTCTTGCCTTTAACAAC
AGTGAAACTGTCAGTTATAAAGAGCTTCAGGACAGCACTCAGATGAATGAAAAGGAACTGACAAAAACAATCAAATCATTACTTGATGTG
AAAATGATTAACCATGATTCAGAAAAGGAAGATATTGATGCAGAATCTTCGTTTTCATTAAATATGAACTTTAGCAGTAAAAGAACAAAA
TTTAAAATTACTACATCAATGCAGAAAGACACACCACAAGTGATTAGCCAGTCAAGAGCTAGGTTTAATCCCAGTATCAGCATGATTAAG
AAGTGTATTGAAGTTCTGATAGACAAACAATACATAGAACGCAGCCAGGCGTCGGCAGATGAATACAGCTACGTCGCGTGATGTCGCTCT
CCTCCAGCGTGGTGTGAGAAGATCATTGCCATCACCATTTGGTGTGTTCCTGTGGGAAAAAGCAGGACTGTGCCTCCATAATTTGGTCAT
TTGGCAGCCCCTGTTTTCTGCTGTTTACAACATCACCAGTGCCACGTCATGAGCGTCAAAGAAAATGCCTAGAGATATTTCAAGCTCATG
TCATTATGACATTTCTTAAAACTTTATTAAAAGAATGAGTGAAGTATTGCTGAAAAGTGGAAATTCGGTTGGGTACCATGCTTTTTCTCC
CCTTCACGTTTGCAGTTGATGTGTCTTTTTTTTTTTTTTTAATGTATCTTAAAGGACATAAAATTTAAAAACTTAAATATTGTAATATGA
CAGATAACCTAATAATTGTATCTACATTAAAATGACAAACATGATACTGCTGCTTGTCAAATAAAAAAAAAATAAAGAAATAGAATGCCT
TTTTTATGTGGATGGAGTATCAGGTTGACCACAAAATATATTGACTCAAAGCAGCTAATGCATCTTTAGTTGCGTTTTTATCTGAATGGT
TTAATTCACTTGTACTCCTATTTAAATCCTACATGAAAAATGTCTAGATTATTGTTCTTGACTGCATAGGACTGCATTCAGCATAAAGAA
TGCTTTATTTTTATGGATTAGATATATTGGATCTAAACATTTTGAATCTTGAAGATGTAATTCCATCAGCAGTTTCTGGTGGTGTGCTAC
TCCACAGACATCGCAGAGTGTGAGCAGGATGCTTGGTGACCTCAAGTCTGGCACAGAGAGAGCTTTTCATTCAAAAGTTGTCTTTCTTCG
GTTGCATAATCCATTAATTCTAGCATAGACTAGTACCCTAGCTCTGTGGCCTTCCCTGAGTCTTAGGAAATCTATGATACCAACATATTC
CTTCTATATGCCTCCCCTACCTGTTACCCTTACAACCCTCCTCCAACAGTTTAGATACTAGAGTCACTCTCATCAATCACAGATGTGCTT
AGCAATGCATAACCTAAATACTTTTTTAAAAAAGAAAATTGTACATTGTACTGGGTGCCACATATATAAATCCCATTATTTTGTTTATTT
TATATATATATATATATATAATATATATATATATATATCTCAACAGCAGTGTTAAGAGTACTGCGATCTATTATCATATTTATTGTCTAT
CCACACCATCACCACCACCACCACACCCCTCCTCCCTCAACATACAATTTTTCTTTATTTTAAAAAAAATAAGAGACGGGGTTTCGCCAT
GTTTCCCAGGCTAGTCTGGAACTTCTGGCCTCAAGCAATCCTATCTCTGTCTCCCAAAGTGCTGGGATTACAAGCATGAGCCACTGCATC
CATCCAACACAAAATTTTTAAAATCGGAATATTTTAAAGCAAATCACACAAATTATTTCACTTATAATACTTCAGTAAGGCCTTTAAAAA
ATCCACAGTGATATTATTACTCCTAACAAAAACAATAATTACTTAGTATCATCTAATATGTGGTTCATATTTAAATTTGTTGTTTTGAGA
TGGGTCTTACAATTGGTTTATTCAATTGCATTTTTTCTAACTCGTGTCTCAAGTGTTTTAAAAATCTACTGAACTTATAATGACTTATAT
AATGTATTTCTCATTTTACCTTTCTTCCAAAAGAGGAAATAATGGCAAACCATATAATATTGTACATTCACTGTCAAAAAGCAAACCCTT

>In-frame_PARD3_ENST00000374790_chr10_34985246_-_CUL2_ENST00000374746_chr10_35360267_-_4451nt
GCGGCCCCGAGCGAGCGCCAGCGCCACACAGCCCCGGGCAGCCGCCGGCGAGCGCGCCGCGACGCCGAACAGGTGGCCGGAGGCTGCGGG
CGCCGCGGCGGGGAGAGGCGAGGCAAGCCCCGGGCGAAGCGAGGCGAGGCGAGGGCGGCCGGGCCGGGCATGCGAGCTGAGCGGCCCCCC
GGCGTCGCCGCCGCCTGCCCGCGCCCCTAGCCGCCCGCGCGCCCGAGTCCCCAGCGGCTCCTCCGCGCCCAGCGTCCTCGGTCCCGGCCT
CGGCTGCTCCGGCTGCGCTCGGCGAGGGGCGCGGGCCCGCCCGCGGCGGCGGCGGCATGAAAGTGACCGTGTGCTTCGGACGGACCCGGG
TGGTCGTGCCGTGCGGGGACGGCCACATGAAAGTTTTCAGCCTCATCCAGCAGGCGGTGACCCGCTACCGGAAGGCCATCGCCAAGGATC
CAAACTACTGGATACAGGTGCATCGCTTGGAACATGGAGATGGAGGAATACTAGACCTTGATGACATTCTTTGTGATGTAGCAGACGATA
AAGACAGAATTTCAACACTACACTTGCACAATGTCTTTGAAACCAAGAGTAGTAGATTTTGATGAAACATGGAACAAACTTTTGACGACA
ATAAAAGCCGTGGTCATGTTGGAATACGTCGAAAGAGCAACATGGAATGACCGTTTCTCAGATATCTATGCTTTATGTGTGGCCTATCCT
GAACCCCTTGGAGAAAGACTTTATACAGAAACTAAGATTTTTTTGGAAAATCATGTTCGGCATTTGCATAAGAGAGTTTTGGAGTCAGAA
GAACAAGTACTTGTTATGTATCATAGGTACTGGGAAGAATACAGCAAGGGTGCAGACTATATGGACTGCTTATATAGGTATCTCAACACC
CAGTTTATTAAAAAGAATAAATTAACAGAAGCGGACCTTCAGTATGGCTATGGTGGTGTAGATATGAATGAACCACTTATGGAAATAGGA
GAGCTAGCATTGGATATGTGGAGGAAATTGATGGTTGAACCACTTCAGGCCATCCTTATCCGAATGCTGCTCCGAGAAATCAAAAATGAT
CGTGGTGGAGAAGACCCAAACCAGAAAGTAATCCATGGGGTTATTAACTCCTTTGTTCATGTTGAACAGTATAAGAAAAAATTCCCCTTA
AAGTTTTATCAGGAAATTTTTGAGTCTCCCTTTCTGACTGAAACAGGAGAGTATTACAAACAAGAAGCTTCAAATTTATTACAAGAATCA
AACTGCTCACAGTATATGGAAAAGGTTCTAGGTAGATTAAAAGATGAAGAAATTCGATGTCGAAAATACCTACATCCAAGTTCATATACT
AAGGTGATTCATGAATGTCAACAACGAATGGTAGCAGACCACTTACAGTTTTTACATGCAGAATGTCATAATATAATTCGACAAGAGAAA
AAAAATGACATGGCAAATATGTACGTCTTACTCCGTGCTGTGTCCACTGGTTTACCTCATATGATTCAGGAGCTGCAAAACCACATCCAT
GATGAGGGCCTTCGAGCAACCAGCAACCTTACTCAGGAAAACATGCCAACACTATTTGTGGAGTCAGTTTTGGAAGTGCATGGTAAATTT
GTTCAGCTTATCAACACTGTTTTGAATGGTGATCAGCATTTTATGAGTGCGTTGGATAAGGCCCTTACGTCAGTTGTAAATTACAGAGAA
CCTAAGTCTGTTTGCAAAGCACCTGAACTGCTTGCTAAGTACTGTGACAACTTACTGAAGAAGTCAGCGAAAGGGATGACAGAGAATGAA
GTGGAAGACAGGCTCACGAGCTTCATCACAGTGTTCAAATACATTGATGACAAGGACGTCTTTCAAAAGTTCTACGCAAGAATGCTGGCA
AAACGTTTAATTCATGGGTTATCCATGTCTATGGACTCTGAAGAAGCCATGATCAACAAATTAAAGCAAGCCTGTGGTTATGAGTTTACC
AGCAAGCTACATCGGATGTATACAGATATGAGTGTCAGCGCTGATCTCAACAATAAGTTCAACAATTTTATCAAAAACCAAGACACAGTA
ATAGATTTGGGAATTAGTTTTCAAATATATGTTCTACAGGCTGGTGCGTGGCCTCTTACTCAGGCTCCTTCATCTACGTTTGCAATTCCC
CAGGAATTAGAAAAAAGTGTACAGATGTTTGAATTATTTTATAGCCAACATTTCAGTGGAAGGAAACTTACATGGTTACATTATCTGTGT
ACAGGTGAAGTTAAAATGAACTATTTGGGCAAACCATATGTAGCCATGGTTACAACATACCAAATGGCAGTTCTTCTTGCCTTTAACAAC
AGTGAAACTGTCAGTTATAAAGAGCTTCAGGACAGCACTCAGATGAATGAAAAGGAACTGACAAAAACAATCAAATCATTACTTGATGTG
AAAATGATTAACCATGATTCAGAAAAGGAAGATATTGATGCAGAATCTTCGTTTTCATTAAATATGAACTTTAGCAGTAAAAGAACAAAA
TTTAAAATTACTACATCAATGCAGAAAGACACACCACAAGTGATTAGCCAGTCAAGAGCTAGGTTTAATCCCAGTATCAGCATGATTAAG
AAGTGTATTGAAGTTCTGATAGACAAACAATACATAGAACGCAGCCAGGCGTCGGCAGATGAATACAGCTACGTCGCGTGATGTCGCTCT
CCTCCAGCGTGGTGTGAGAAGATCATTGCCATCACCATTTGGTGTGTTCCTGTGGGAAAAAGCAGGACTGTGCCTCCATAATTTGGTCAT
TTGGCAGCCCCTGTTTTCTGCTGTTTACAACATCACCAGTGCCACGTCATGAGCGTCAAAGAAAATGCCTAGAGATATTTCAAGCTCATG
TCATTATGACATTTCTTAAAACTTTATTAAAAGAATGAGTGAAGTATTGCTGAAAAGTGGAAATTCGGTTGGGTACCATGCTTTTTCTCC
CCTTCACGTTTGCAGTTGATGTGTCTTTTTTTTTTTTTTTAATGTATCTTAAAGGACATAAAATTTAAAAACTTAAATATTGTAATATGA
CAGATAACCTAATAATTGTATCTACATTAAAATGACAAACATGATACTGCTGCTTGTCAAATAAAAAAAAAATAAAGAAATAGAATGCCT
TTTTTATGTGGATGGAGTATCAGGTTGACCACAAAATATATTGACTCAAAGCAGCTAATGCATCTTTAGTTGCGTTTTTATCTGAATGGT
TTAATTCACTTGTACTCCTATTTAAATCCTACATGAAAAATGTCTAGATTATTGTTCTTGACTGCATAGGACTGCATTCAGCATAAAGAA
TGCTTTATTTTTATGGATTAGATATATTGGATCTAAACATTTTGAATCTTGAAGATGTAATTCCATCAGCAGTTTCTGGTGGTGTGCTAC
TCCACAGACATCGCAGAGTGTGAGCAGGATGCTTGGTGACCTCAAGTCTGGCACAGAGAGAGCTTTTCATTCAAAAGTTGTCTTTCTTCG
GTTGCATAATCCATTAATTCTAGCATAGACTAGTACCCTAGCTCTGTGGCCTTCCCTGAGTCTTAGGAAATCTATGATACCAACATATTC
CTTCTATATGCCTCCCCTACCTGTTACCCTTACAACCCTCCTCCAACAGTTTAGATACTAGAGTCACTCTCATCAATCACAGATGTGCTT
AGCAATGCATAACCTAAATACTTTTTTAAAAAAGAAAATTGTACATTGTACTGGGTGCCACATATATAAATCCCATTATTTTGTTTATTT
TATATATATATATATATATAATATATATATATATATATCTCAACAGCAGTGTTAAGAGTACTGCGATCTATTATCATATTTATTGTCTAT
CCACACCATCACCACCACCACCACACCCCTCCTCCCTCAACATACAATTTTTCTTTATTTTAAAAAAAATAAGAGACGGGGTTTCGCCAT
GTTTCCCAGGCTAGTCTGGAACTTCTGGCCTCAAGCAATCCTATCTCTGTCTCCCAAAGTGCTGGGATTACAAGCATGAGCCACTGCATC
CATCCAACACAAAATTTTTAAAATCGGAATATTTTAAAGCAAATCACACAAATTATTTCACTTATAATACTTCAGTAAGGCCTTTAAAAA
ATCCACAGTGATATTATTACTCCTAACAAAAACAATAATTACTTAGTATCATCTAATATGTGGTTCATATTTAAATTTGTTGTTTTGAGA
TGGGTCTTACAATTGGTTTATTCAATTGCATTTTTTCTAACTCGTGTCTCAAGTGTTTTAAAAATCTACTGAACTTATAATGACTTATAT
AATGTATTTCTCATTTTACCTTTCTTCCAAAAGAGGAAATAATGGCAAACCATATAATATTGTACATTCACTGTCAAAAAGCAAACCCTT

>In-frame_PARD3_ENST00000374794_chr10_34985246_-_CUL2_ENST00000374746_chr10_35360267_-_4451nt
GCGGCCCCGAGCGAGCGCCAGCGCCACACAGCCCCGGGCAGCCGCCGGCGAGCGCGCCGCGACGCCGAACAGGTGGCCGGAGGCTGCGGG
CGCCGCGGCGGGGAGAGGCGAGGCAAGCCCCGGGCGAAGCGAGGCGAGGCGAGGGCGGCCGGGCCGGGCATGCGAGCTGAGCGGCCCCCC
GGCGTCGCCGCCGCCTGCCCGCGCCCCTAGCCGCCCGCGCGCCCGAGTCCCCAGCGGCTCCTCCGCGCCCAGCGTCCTCGGTCCCGGCCT
CGGCTGCTCCGGCTGCGCTCGGCGAGGGGCGCGGGCCCGCCCGCGGCGGCGGCGGCATGAAAGTGACCGTGTGCTTCGGACGGACCCGGG
TGGTCGTGCCGTGCGGGGACGGCCACATGAAAGTTTTCAGCCTCATCCAGCAGGCGGTGACCCGCTACCGGAAGGCCATCGCCAAGGATC
CAAACTACTGGATACAGGTGCATCGCTTGGAACATGGAGATGGAGGAATACTAGACCTTGATGACATTCTTTGTGATGTAGCAGACGATA
AAGACAGAATTTCAACACTACACTTGCACAATGTCTTTGAAACCAAGAGTAGTAGATTTTGATGAAACATGGAACAAACTTTTGACGACA
ATAAAAGCCGTGGTCATGTTGGAATACGTCGAAAGAGCAACATGGAATGACCGTTTCTCAGATATCTATGCTTTATGTGTGGCCTATCCT
GAACCCCTTGGAGAAAGACTTTATACAGAAACTAAGATTTTTTTGGAAAATCATGTTCGGCATTTGCATAAGAGAGTTTTGGAGTCAGAA
GAACAAGTACTTGTTATGTATCATAGGTACTGGGAAGAATACAGCAAGGGTGCAGACTATATGGACTGCTTATATAGGTATCTCAACACC
CAGTTTATTAAAAAGAATAAATTAACAGAAGCGGACCTTCAGTATGGCTATGGTGGTGTAGATATGAATGAACCACTTATGGAAATAGGA
GAGCTAGCATTGGATATGTGGAGGAAATTGATGGTTGAACCACTTCAGGCCATCCTTATCCGAATGCTGCTCCGAGAAATCAAAAATGAT
CGTGGTGGAGAAGACCCAAACCAGAAAGTAATCCATGGGGTTATTAACTCCTTTGTTCATGTTGAACAGTATAAGAAAAAATTCCCCTTA
AAGTTTTATCAGGAAATTTTTGAGTCTCCCTTTCTGACTGAAACAGGAGAGTATTACAAACAAGAAGCTTCAAATTTATTACAAGAATCA
AACTGCTCACAGTATATGGAAAAGGTTCTAGGTAGATTAAAAGATGAAGAAATTCGATGTCGAAAATACCTACATCCAAGTTCATATACT
AAGGTGATTCATGAATGTCAACAACGAATGGTAGCAGACCACTTACAGTTTTTACATGCAGAATGTCATAATATAATTCGACAAGAGAAA
AAAAATGACATGGCAAATATGTACGTCTTACTCCGTGCTGTGTCCACTGGTTTACCTCATATGATTCAGGAGCTGCAAAACCACATCCAT
GATGAGGGCCTTCGAGCAACCAGCAACCTTACTCAGGAAAACATGCCAACACTATTTGTGGAGTCAGTTTTGGAAGTGCATGGTAAATTT
GTTCAGCTTATCAACACTGTTTTGAATGGTGATCAGCATTTTATGAGTGCGTTGGATAAGGCCCTTACGTCAGTTGTAAATTACAGAGAA
CCTAAGTCTGTTTGCAAAGCACCTGAACTGCTTGCTAAGTACTGTGACAACTTACTGAAGAAGTCAGCGAAAGGGATGACAGAGAATGAA
GTGGAAGACAGGCTCACGAGCTTCATCACAGTGTTCAAATACATTGATGACAAGGACGTCTTTCAAAAGTTCTACGCAAGAATGCTGGCA
AAACGTTTAATTCATGGGTTATCCATGTCTATGGACTCTGAAGAAGCCATGATCAACAAATTAAAGCAAGCCTGTGGTTATGAGTTTACC
AGCAAGCTACATCGGATGTATACAGATATGAGTGTCAGCGCTGATCTCAACAATAAGTTCAACAATTTTATCAAAAACCAAGACACAGTA
ATAGATTTGGGAATTAGTTTTCAAATATATGTTCTACAGGCTGGTGCGTGGCCTCTTACTCAGGCTCCTTCATCTACGTTTGCAATTCCC
CAGGAATTAGAAAAAAGTGTACAGATGTTTGAATTATTTTATAGCCAACATTTCAGTGGAAGGAAACTTACATGGTTACATTATCTGTGT
ACAGGTGAAGTTAAAATGAACTATTTGGGCAAACCATATGTAGCCATGGTTACAACATACCAAATGGCAGTTCTTCTTGCCTTTAACAAC
AGTGAAACTGTCAGTTATAAAGAGCTTCAGGACAGCACTCAGATGAATGAAAAGGAACTGACAAAAACAATCAAATCATTACTTGATGTG
AAAATGATTAACCATGATTCAGAAAAGGAAGATATTGATGCAGAATCTTCGTTTTCATTAAATATGAACTTTAGCAGTAAAAGAACAAAA
TTTAAAATTACTACATCAATGCAGAAAGACACACCACAAGTGATTAGCCAGTCAAGAGCTAGGTTTAATCCCAGTATCAGCATGATTAAG
AAGTGTATTGAAGTTCTGATAGACAAACAATACATAGAACGCAGCCAGGCGTCGGCAGATGAATACAGCTACGTCGCGTGATGTCGCTCT
CCTCCAGCGTGGTGTGAGAAGATCATTGCCATCACCATTTGGTGTGTTCCTGTGGGAAAAAGCAGGACTGTGCCTCCATAATTTGGTCAT
TTGGCAGCCCCTGTTTTCTGCTGTTTACAACATCACCAGTGCCACGTCATGAGCGTCAAAGAAAATGCCTAGAGATATTTCAAGCTCATG
TCATTATGACATTTCTTAAAACTTTATTAAAAGAATGAGTGAAGTATTGCTGAAAAGTGGAAATTCGGTTGGGTACCATGCTTTTTCTCC
CCTTCACGTTTGCAGTTGATGTGTCTTTTTTTTTTTTTTTAATGTATCTTAAAGGACATAAAATTTAAAAACTTAAATATTGTAATATGA
CAGATAACCTAATAATTGTATCTACATTAAAATGACAAACATGATACTGCTGCTTGTCAAATAAAAAAAAAATAAAGAAATAGAATGCCT
TTTTTATGTGGATGGAGTATCAGGTTGACCACAAAATATATTGACTCAAAGCAGCTAATGCATCTTTAGTTGCGTTTTTATCTGAATGGT
TTAATTCACTTGTACTCCTATTTAAATCCTACATGAAAAATGTCTAGATTATTGTTCTTGACTGCATAGGACTGCATTCAGCATAAAGAA
TGCTTTATTTTTATGGATTAGATATATTGGATCTAAACATTTTGAATCTTGAAGATGTAATTCCATCAGCAGTTTCTGGTGGTGTGCTAC
TCCACAGACATCGCAGAGTGTGAGCAGGATGCTTGGTGACCTCAAGTCTGGCACAGAGAGAGCTTTTCATTCAAAAGTTGTCTTTCTTCG
GTTGCATAATCCATTAATTCTAGCATAGACTAGTACCCTAGCTCTGTGGCCTTCCCTGAGTCTTAGGAAATCTATGATACCAACATATTC
CTTCTATATGCCTCCCCTACCTGTTACCCTTACAACCCTCCTCCAACAGTTTAGATACTAGAGTCACTCTCATCAATCACAGATGTGCTT
AGCAATGCATAACCTAAATACTTTTTTAAAAAAGAAAATTGTACATTGTACTGGGTGCCACATATATAAATCCCATTATTTTGTTTATTT
TATATATATATATATATATAATATATATATATATATATCTCAACAGCAGTGTTAAGAGTACTGCGATCTATTATCATATTTATTGTCTAT
CCACACCATCACCACCACCACCACACCCCTCCTCCCTCAACATACAATTTTTCTTTATTTTAAAAAAAATAAGAGACGGGGTTTCGCCAT
GTTTCCCAGGCTAGTCTGGAACTTCTGGCCTCAAGCAATCCTATCTCTGTCTCCCAAAGTGCTGGGATTACAAGCATGAGCCACTGCATC
CATCCAACACAAAATTTTTAAAATCGGAATATTTTAAAGCAAATCACACAAATTATTTCACTTATAATACTTCAGTAAGGCCTTTAAAAA
ATCCACAGTGATATTATTACTCCTAACAAAAACAATAATTACTTAGTATCATCTAATATGTGGTTCATATTTAAATTTGTTGTTTTGAGA
TGGGTCTTACAATTGGTTTATTCAATTGCATTTTTTCTAACTCGTGTCTCAAGTGTTTTAAAAATCTACTGAACTTATAATGACTTATAT
AATGTATTTCTCATTTTACCTTTCTTCCAAAAGAGGAAATAATGGCAAACCATATAATATTGTACATTCACTGTCAAAAAGCAAACCCTT

>In-frame_PARD3_ENST00000374788_chr10_34985246_-_CUL2_ENST00000374746_chr10_35360267_-_4451nt
GCGGCCCCGAGCGAGCGCCAGCGCCACACAGCCCCGGGCAGCCGCCGGCGAGCGCGCCGCGACGCCGAACAGGTGGCCGGAGGCTGCGGG
CGCCGCGGCGGGGAGAGGCGAGGCAAGCCCCGGGCGAAGCGAGGCGAGGCGAGGGCGGCCGGGCCGGGCATGCGAGCTGAGCGGCCCCCC
GGCGTCGCCGCCGCCTGCCCGCGCCCCTAGCCGCCCGCGCGCCCGAGTCCCCAGCGGCTCCTCCGCGCCCAGCGTCCTCGGTCCCGGCCT
CGGCTGCTCCGGCTGCGCTCGGCGAGGGGCGCGGGCCCGCCCGCGGCGGCGGCGGCATGAAAGTGACCGTGTGCTTCGGACGGACCCGGG
TGGTCGTGCCGTGCGGGGACGGCCACATGAAAGTTTTCAGCCTCATCCAGCAGGCGGTGACCCGCTACCGGAAGGCCATCGCCAAGGATC
CAAACTACTGGATACAGGTGCATCGCTTGGAACATGGAGATGGAGGAATACTAGACCTTGATGACATTCTTTGTGATGTAGCAGACGATA
AAGACAGAATTTCAACACTACACTTGCACAATGTCTTTGAAACCAAGAGTAGTAGATTTTGATGAAACATGGAACAAACTTTTGACGACA
ATAAAAGCCGTGGTCATGTTGGAATACGTCGAAAGAGCAACATGGAATGACCGTTTCTCAGATATCTATGCTTTATGTGTGGCCTATCCT
GAACCCCTTGGAGAAAGACTTTATACAGAAACTAAGATTTTTTTGGAAAATCATGTTCGGCATTTGCATAAGAGAGTTTTGGAGTCAGAA
GAACAAGTACTTGTTATGTATCATAGGTACTGGGAAGAATACAGCAAGGGTGCAGACTATATGGACTGCTTATATAGGTATCTCAACACC
CAGTTTATTAAAAAGAATAAATTAACAGAAGCGGACCTTCAGTATGGCTATGGTGGTGTAGATATGAATGAACCACTTATGGAAATAGGA
GAGCTAGCATTGGATATGTGGAGGAAATTGATGGTTGAACCACTTCAGGCCATCCTTATCCGAATGCTGCTCCGAGAAATCAAAAATGAT
CGTGGTGGAGAAGACCCAAACCAGAAAGTAATCCATGGGGTTATTAACTCCTTTGTTCATGTTGAACAGTATAAGAAAAAATTCCCCTTA
AAGTTTTATCAGGAAATTTTTGAGTCTCCCTTTCTGACTGAAACAGGAGAGTATTACAAACAAGAAGCTTCAAATTTATTACAAGAATCA
AACTGCTCACAGTATATGGAAAAGGTTCTAGGTAGATTAAAAGATGAAGAAATTCGATGTCGAAAATACCTACATCCAAGTTCATATACT
AAGGTGATTCATGAATGTCAACAACGAATGGTAGCAGACCACTTACAGTTTTTACATGCAGAATGTCATAATATAATTCGACAAGAGAAA
AAAAATGACATGGCAAATATGTACGTCTTACTCCGTGCTGTGTCCACTGGTTTACCTCATATGATTCAGGAGCTGCAAAACCACATCCAT
GATGAGGGCCTTCGAGCAACCAGCAACCTTACTCAGGAAAACATGCCAACACTATTTGTGGAGTCAGTTTTGGAAGTGCATGGTAAATTT
GTTCAGCTTATCAACACTGTTTTGAATGGTGATCAGCATTTTATGAGTGCGTTGGATAAGGCCCTTACGTCAGTTGTAAATTACAGAGAA
CCTAAGTCTGTTTGCAAAGCACCTGAACTGCTTGCTAAGTACTGTGACAACTTACTGAAGAAGTCAGCGAAAGGGATGACAGAGAATGAA
GTGGAAGACAGGCTCACGAGCTTCATCACAGTGTTCAAATACATTGATGACAAGGACGTCTTTCAAAAGTTCTACGCAAGAATGCTGGCA
AAACGTTTAATTCATGGGTTATCCATGTCTATGGACTCTGAAGAAGCCATGATCAACAAATTAAAGCAAGCCTGTGGTTATGAGTTTACC
AGCAAGCTACATCGGATGTATACAGATATGAGTGTCAGCGCTGATCTCAACAATAAGTTCAACAATTTTATCAAAAACCAAGACACAGTA
ATAGATTTGGGAATTAGTTTTCAAATATATGTTCTACAGGCTGGTGCGTGGCCTCTTACTCAGGCTCCTTCATCTACGTTTGCAATTCCC
CAGGAATTAGAAAAAAGTGTACAGATGTTTGAATTATTTTATAGCCAACATTTCAGTGGAAGGAAACTTACATGGTTACATTATCTGTGT
ACAGGTGAAGTTAAAATGAACTATTTGGGCAAACCATATGTAGCCATGGTTACAACATACCAAATGGCAGTTCTTCTTGCCTTTAACAAC
AGTGAAACTGTCAGTTATAAAGAGCTTCAGGACAGCACTCAGATGAATGAAAAGGAACTGACAAAAACAATCAAATCATTACTTGATGTG
AAAATGATTAACCATGATTCAGAAAAGGAAGATATTGATGCAGAATCTTCGTTTTCATTAAATATGAACTTTAGCAGTAAAAGAACAAAA
TTTAAAATTACTACATCAATGCAGAAAGACACACCACAAGTGATTAGCCAGTCAAGAGCTAGGTTTAATCCCAGTATCAGCATGATTAAG
AAGTGTATTGAAGTTCTGATAGACAAACAATACATAGAACGCAGCCAGGCGTCGGCAGATGAATACAGCTACGTCGCGTGATGTCGCTCT
CCTCCAGCGTGGTGTGAGAAGATCATTGCCATCACCATTTGGTGTGTTCCTGTGGGAAAAAGCAGGACTGTGCCTCCATAATTTGGTCAT
TTGGCAGCCCCTGTTTTCTGCTGTTTACAACATCACCAGTGCCACGTCATGAGCGTCAAAGAAAATGCCTAGAGATATTTCAAGCTCATG
TCATTATGACATTTCTTAAAACTTTATTAAAAGAATGAGTGAAGTATTGCTGAAAAGTGGAAATTCGGTTGGGTACCATGCTTTTTCTCC
CCTTCACGTTTGCAGTTGATGTGTCTTTTTTTTTTTTTTTAATGTATCTTAAAGGACATAAAATTTAAAAACTTAAATATTGTAATATGA
CAGATAACCTAATAATTGTATCTACATTAAAATGACAAACATGATACTGCTGCTTGTCAAATAAAAAAAAAATAAAGAAATAGAATGCCT
TTTTTATGTGGATGGAGTATCAGGTTGACCACAAAATATATTGACTCAAAGCAGCTAATGCATCTTTAGTTGCGTTTTTATCTGAATGGT
TTAATTCACTTGTACTCCTATTTAAATCCTACATGAAAAATGTCTAGATTATTGTTCTTGACTGCATAGGACTGCATTCAGCATAAAGAA
TGCTTTATTTTTATGGATTAGATATATTGGATCTAAACATTTTGAATCTTGAAGATGTAATTCCATCAGCAGTTTCTGGTGGTGTGCTAC
TCCACAGACATCGCAGAGTGTGAGCAGGATGCTTGGTGACCTCAAGTCTGGCACAGAGAGAGCTTTTCATTCAAAAGTTGTCTTTCTTCG
GTTGCATAATCCATTAATTCTAGCATAGACTAGTACCCTAGCTCTGTGGCCTTCCCTGAGTCTTAGGAAATCTATGATACCAACATATTC
CTTCTATATGCCTCCCCTACCTGTTACCCTTACAACCCTCCTCCAACAGTTTAGATACTAGAGTCACTCTCATCAATCACAGATGTGCTT
AGCAATGCATAACCTAAATACTTTTTTAAAAAAGAAAATTGTACATTGTACTGGGTGCCACATATATAAATCCCATTATTTTGTTTATTT
TATATATATATATATATATAATATATATATATATATATCTCAACAGCAGTGTTAAGAGTACTGCGATCTATTATCATATTTATTGTCTAT
CCACACCATCACCACCACCACCACACCCCTCCTCCCTCAACATACAATTTTTCTTTATTTTAAAAAAAATAAGAGACGGGGTTTCGCCAT
GTTTCCCAGGCTAGTCTGGAACTTCTGGCCTCAAGCAATCCTATCTCTGTCTCCCAAAGTGCTGGGATTACAAGCATGAGCCACTGCATC
CATCCAACACAAAATTTTTAAAATCGGAATATTTTAAAGCAAATCACACAAATTATTTCACTTATAATACTTCAGTAAGGCCTTTAAAAA
ATCCACAGTGATATTATTACTCCTAACAAAAACAATAATTACTTAGTATCATCTAATATGTGGTTCATATTTAAATTTGTTGTTTTGAGA
TGGGTCTTACAATTGGTTTATTCAATTGCATTTTTTCTAACTCGTGTCTCAAGTGTTTTAAAAATCTACTGAACTTATAATGACTTATAT
AATGTATTTCTCATTTTACCTTTCTTCCAAAAGAGGAAATAATGGCAAACCATATAATATTGTACATTCACTGTCAAAAAGCAAACCCTT

>In-frame_PARD3_ENST00000374776_chr10_34985246_-_CUL2_ENST00000374746_chr10_35360267_-_4451nt
GCGGCCCCGAGCGAGCGCCAGCGCCACACAGCCCCGGGCAGCCGCCGGCGAGCGCGCCGCGACGCCGAACAGGTGGCCGGAGGCTGCGGG
CGCCGCGGCGGGGAGAGGCGAGGCAAGCCCCGGGCGAAGCGAGGCGAGGCGAGGGCGGCCGGGCCGGGCATGCGAGCTGAGCGGCCCCCC
GGCGTCGCCGCCGCCTGCCCGCGCCCCTAGCCGCCCGCGCGCCCGAGTCCCCAGCGGCTCCTCCGCGCCCAGCGTCCTCGGTCCCGGCCT
CGGCTGCTCCGGCTGCGCTCGGCGAGGGGCGCGGGCCCGCCCGCGGCGGCGGCGGCATGAAAGTGACCGTGTGCTTCGGACGGACCCGGG
TGGTCGTGCCGTGCGGGGACGGCCACATGAAAGTTTTCAGCCTCATCCAGCAGGCGGTGACCCGCTACCGGAAGGCCATCGCCAAGGATC
CAAACTACTGGATACAGGTGCATCGCTTGGAACATGGAGATGGAGGAATACTAGACCTTGATGACATTCTTTGTGATGTAGCAGACGATA
AAGACAGAATTTCAACACTACACTTGCACAATGTCTTTGAAACCAAGAGTAGTAGATTTTGATGAAACATGGAACAAACTTTTGACGACA
ATAAAAGCCGTGGTCATGTTGGAATACGTCGAAAGAGCAACATGGAATGACCGTTTCTCAGATATCTATGCTTTATGTGTGGCCTATCCT
GAACCCCTTGGAGAAAGACTTTATACAGAAACTAAGATTTTTTTGGAAAATCATGTTCGGCATTTGCATAAGAGAGTTTTGGAGTCAGAA
GAACAAGTACTTGTTATGTATCATAGGTACTGGGAAGAATACAGCAAGGGTGCAGACTATATGGACTGCTTATATAGGTATCTCAACACC
CAGTTTATTAAAAAGAATAAATTAACAGAAGCGGACCTTCAGTATGGCTATGGTGGTGTAGATATGAATGAACCACTTATGGAAATAGGA
GAGCTAGCATTGGATATGTGGAGGAAATTGATGGTTGAACCACTTCAGGCCATCCTTATCCGAATGCTGCTCCGAGAAATCAAAAATGAT
CGTGGTGGAGAAGACCCAAACCAGAAAGTAATCCATGGGGTTATTAACTCCTTTGTTCATGTTGAACAGTATAAGAAAAAATTCCCCTTA
AAGTTTTATCAGGAAATTTTTGAGTCTCCCTTTCTGACTGAAACAGGAGAGTATTACAAACAAGAAGCTTCAAATTTATTACAAGAATCA
AACTGCTCACAGTATATGGAAAAGGTTCTAGGTAGATTAAAAGATGAAGAAATTCGATGTCGAAAATACCTACATCCAAGTTCATATACT
AAGGTGATTCATGAATGTCAACAACGAATGGTAGCAGACCACTTACAGTTTTTACATGCAGAATGTCATAATATAATTCGACAAGAGAAA
AAAAATGACATGGCAAATATGTACGTCTTACTCCGTGCTGTGTCCACTGGTTTACCTCATATGATTCAGGAGCTGCAAAACCACATCCAT
GATGAGGGCCTTCGAGCAACCAGCAACCTTACTCAGGAAAACATGCCAACACTATTTGTGGAGTCAGTTTTGGAAGTGCATGGTAAATTT
GTTCAGCTTATCAACACTGTTTTGAATGGTGATCAGCATTTTATGAGTGCGTTGGATAAGGCCCTTACGTCAGTTGTAAATTACAGAGAA
CCTAAGTCTGTTTGCAAAGCACCTGAACTGCTTGCTAAGTACTGTGACAACTTACTGAAGAAGTCAGCGAAAGGGATGACAGAGAATGAA
GTGGAAGACAGGCTCACGAGCTTCATCACAGTGTTCAAATACATTGATGACAAGGACGTCTTTCAAAAGTTCTACGCAAGAATGCTGGCA
AAACGTTTAATTCATGGGTTATCCATGTCTATGGACTCTGAAGAAGCCATGATCAACAAATTAAAGCAAGCCTGTGGTTATGAGTTTACC
AGCAAGCTACATCGGATGTATACAGATATGAGTGTCAGCGCTGATCTCAACAATAAGTTCAACAATTTTATCAAAAACCAAGACACAGTA
ATAGATTTGGGAATTAGTTTTCAAATATATGTTCTACAGGCTGGTGCGTGGCCTCTTACTCAGGCTCCTTCATCTACGTTTGCAATTCCC
CAGGAATTAGAAAAAAGTGTACAGATGTTTGAATTATTTTATAGCCAACATTTCAGTGGAAGGAAACTTACATGGTTACATTATCTGTGT
ACAGGTGAAGTTAAAATGAACTATTTGGGCAAACCATATGTAGCCATGGTTACAACATACCAAATGGCAGTTCTTCTTGCCTTTAACAAC
AGTGAAACTGTCAGTTATAAAGAGCTTCAGGACAGCACTCAGATGAATGAAAAGGAACTGACAAAAACAATCAAATCATTACTTGATGTG
AAAATGATTAACCATGATTCAGAAAAGGAAGATATTGATGCAGAATCTTCGTTTTCATTAAATATGAACTTTAGCAGTAAAAGAACAAAA
TTTAAAATTACTACATCAATGCAGAAAGACACACCACAAGTGATTAGCCAGTCAAGAGCTAGGTTTAATCCCAGTATCAGCATGATTAAG
AAGTGTATTGAAGTTCTGATAGACAAACAATACATAGAACGCAGCCAGGCGTCGGCAGATGAATACAGCTACGTCGCGTGATGTCGCTCT
CCTCCAGCGTGGTGTGAGAAGATCATTGCCATCACCATTTGGTGTGTTCCTGTGGGAAAAAGCAGGACTGTGCCTCCATAATTTGGTCAT
TTGGCAGCCCCTGTTTTCTGCTGTTTACAACATCACCAGTGCCACGTCATGAGCGTCAAAGAAAATGCCTAGAGATATTTCAAGCTCATG
TCATTATGACATTTCTTAAAACTTTATTAAAAGAATGAGTGAAGTATTGCTGAAAAGTGGAAATTCGGTTGGGTACCATGCTTTTTCTCC
CCTTCACGTTTGCAGTTGATGTGTCTTTTTTTTTTTTTTTAATGTATCTTAAAGGACATAAAATTTAAAAACTTAAATATTGTAATATGA
CAGATAACCTAATAATTGTATCTACATTAAAATGACAAACATGATACTGCTGCTTGTCAAATAAAAAAAAAATAAAGAAATAGAATGCCT
TTTTTATGTGGATGGAGTATCAGGTTGACCACAAAATATATTGACTCAAAGCAGCTAATGCATCTTTAGTTGCGTTTTTATCTGAATGGT
TTAATTCACTTGTACTCCTATTTAAATCCTACATGAAAAATGTCTAGATTATTGTTCTTGACTGCATAGGACTGCATTCAGCATAAAGAA
TGCTTTATTTTTATGGATTAGATATATTGGATCTAAACATTTTGAATCTTGAAGATGTAATTCCATCAGCAGTTTCTGGTGGTGTGCTAC
TCCACAGACATCGCAGAGTGTGAGCAGGATGCTTGGTGACCTCAAGTCTGGCACAGAGAGAGCTTTTCATTCAAAAGTTGTCTTTCTTCG
GTTGCATAATCCATTAATTCTAGCATAGACTAGTACCCTAGCTCTGTGGCCTTCCCTGAGTCTTAGGAAATCTATGATACCAACATATTC
CTTCTATATGCCTCCCCTACCTGTTACCCTTACAACCCTCCTCCAACAGTTTAGATACTAGAGTCACTCTCATCAATCACAGATGTGCTT
AGCAATGCATAACCTAAATACTTTTTTAAAAAAGAAAATTGTACATTGTACTGGGTGCCACATATATAAATCCCATTATTTTGTTTATTT
TATATATATATATATATATAATATATATATATATATATCTCAACAGCAGTGTTAAGAGTACTGCGATCTATTATCATATTTATTGTCTAT
CCACACCATCACCACCACCACCACACCCCTCCTCCCTCAACATACAATTTTTCTTTATTTTAAAAAAAATAAGAGACGGGGTTTCGCCAT
GTTTCCCAGGCTAGTCTGGAACTTCTGGCCTCAAGCAATCCTATCTCTGTCTCCCAAAGTGCTGGGATTACAAGCATGAGCCACTGCATC
CATCCAACACAAAATTTTTAAAATCGGAATATTTTAAAGCAAATCACACAAATTATTTCACTTATAATACTTCAGTAAGGCCTTTAAAAA
ATCCACAGTGATATTATTACTCCTAACAAAAACAATAATTACTTAGTATCATCTAATATGTGGTTCATATTTAAATTTGTTGTTTTGAGA
TGGGTCTTACAATTGGTTTATTCAATTGCATTTTTTCTAACTCGTGTCTCAAGTGTTTTAAAAATCTACTGAACTTATAATGACTTATAT
AATGTATTTCTCATTTTACCTTTCTTCCAAAAGAGGAAATAATGGCAAACCATATAATATTGTACATTCACTGTCAAAAAGCAAACCCTT

>In-frame_PARD3_ENST00000340077_chr10_34985246_-_CUL2_ENST00000374746_chr10_35360267_-_4455nt
CCCAGCGGCCCCGAGCGAGCGCCAGCGCCACACAGCCCCGGGCAGCCGCCGGCGAGCGCGCCGCGACGCCGAACAGGTGGCCGGAGGCTG
CGGGCGCCGCGGCGGGGAGAGGCGAGGCAAGCCCCGGGCGAAGCGAGGCGAGGCGAGGGCGGCCGGGCCGGGCATGCGAGCTGAGCGGCC
CCCCGGCGTCGCCGCCGCCTGCCCGCGCCCCTAGCCGCCCGCGCGCCCGAGTCCCCAGCGGCTCCTCCGCGCCCAGCGTCCTCGGTCCCG
GCCTCGGCTGCTCCGGCTGCGCTCGGCGAGGGGCGCGGGCCCGCCCGCGGCGGCGGCGGCATGAAAGTGACCGTGTGCTTCGGACGGACC
CGGGTGGTCGTGCCGTGCGGGGACGGCCACATGAAAGTTTTCAGCCTCATCCAGCAGGCGGTGACCCGCTACCGGAAGGCCATCGCCAAG
GATCCAAACTACTGGATACAGGTGCATCGCTTGGAACATGGAGATGGAGGAATACTAGACCTTGATGACATTCTTTGTGATGTAGCAGAC
GATAAAGACAGAATTTCAACACTACACTTGCACAATGTCTTTGAAACCAAGAGTAGTAGATTTTGATGAAACATGGAACAAACTTTTGAC
GACAATAAAAGCCGTGGTCATGTTGGAATACGTCGAAAGAGCAACATGGAATGACCGTTTCTCAGATATCTATGCTTTATGTGTGGCCTA
TCCTGAACCCCTTGGAGAAAGACTTTATACAGAAACTAAGATTTTTTTGGAAAATCATGTTCGGCATTTGCATAAGAGAGTTTTGGAGTC
AGAAGAACAAGTACTTGTTATGTATCATAGGTACTGGGAAGAATACAGCAAGGGTGCAGACTATATGGACTGCTTATATAGGTATCTCAA
CACCCAGTTTATTAAAAAGAATAAATTAACAGAAGCGGACCTTCAGTATGGCTATGGTGGTGTAGATATGAATGAACCACTTATGGAAAT
AGGAGAGCTAGCATTGGATATGTGGAGGAAATTGATGGTTGAACCACTTCAGGCCATCCTTATCCGAATGCTGCTCCGAGAAATCAAAAA
TGATCGTGGTGGAGAAGACCCAAACCAGAAAGTAATCCATGGGGTTATTAACTCCTTTGTTCATGTTGAACAGTATAAGAAAAAATTCCC
CTTAAAGTTTTATCAGGAAATTTTTGAGTCTCCCTTTCTGACTGAAACAGGAGAGTATTACAAACAAGAAGCTTCAAATTTATTACAAGA
ATCAAACTGCTCACAGTATATGGAAAAGGTTCTAGGTAGATTAAAAGATGAAGAAATTCGATGTCGAAAATACCTACATCCAAGTTCATA
TACTAAGGTGATTCATGAATGTCAACAACGAATGGTAGCAGACCACTTACAGTTTTTACATGCAGAATGTCATAATATAATTCGACAAGA
GAAAAAAAATGACATGGCAAATATGTACGTCTTACTCCGTGCTGTGTCCACTGGTTTACCTCATATGATTCAGGAGCTGCAAAACCACAT
CCATGATGAGGGCCTTCGAGCAACCAGCAACCTTACTCAGGAAAACATGCCAACACTATTTGTGGAGTCAGTTTTGGAAGTGCATGGTAA
ATTTGTTCAGCTTATCAACACTGTTTTGAATGGTGATCAGCATTTTATGAGTGCGTTGGATAAGGCCCTTACGTCAGTTGTAAATTACAG
AGAACCTAAGTCTGTTTGCAAAGCACCTGAACTGCTTGCTAAGTACTGTGACAACTTACTGAAGAAGTCAGCGAAAGGGATGACAGAGAA
TGAAGTGGAAGACAGGCTCACGAGCTTCATCACAGTGTTCAAATACATTGATGACAAGGACGTCTTTCAAAAGTTCTACGCAAGAATGCT
GGCAAAACGTTTAATTCATGGGTTATCCATGTCTATGGACTCTGAAGAAGCCATGATCAACAAATTAAAGCAAGCCTGTGGTTATGAGTT
TACCAGCAAGCTACATCGGATGTATACAGATATGAGTGTCAGCGCTGATCTCAACAATAAGTTCAACAATTTTATCAAAAACCAAGACAC
AGTAATAGATTTGGGAATTAGTTTTCAAATATATGTTCTACAGGCTGGTGCGTGGCCTCTTACTCAGGCTCCTTCATCTACGTTTGCAAT
TCCCCAGGAATTAGAAAAAAGTGTACAGATGTTTGAATTATTTTATAGCCAACATTTCAGTGGAAGGAAACTTACATGGTTACATTATCT
GTGTACAGGTGAAGTTAAAATGAACTATTTGGGCAAACCATATGTAGCCATGGTTACAACATACCAAATGGCAGTTCTTCTTGCCTTTAA
CAACAGTGAAACTGTCAGTTATAAAGAGCTTCAGGACAGCACTCAGATGAATGAAAAGGAACTGACAAAAACAATCAAATCATTACTTGA
TGTGAAAATGATTAACCATGATTCAGAAAAGGAAGATATTGATGCAGAATCTTCGTTTTCATTAAATATGAACTTTAGCAGTAAAAGAAC
AAAATTTAAAATTACTACATCAATGCAGAAAGACACACCACAAGTGATTAGCCAGTCAAGAGCTAGGTTTAATCCCAGTATCAGCATGAT
TAAGAAGTGTATTGAAGTTCTGATAGACAAACAATACATAGAACGCAGCCAGGCGTCGGCAGATGAATACAGCTACGTCGCGTGATGTCG
CTCTCCTCCAGCGTGGTGTGAGAAGATCATTGCCATCACCATTTGGTGTGTTCCTGTGGGAAAAAGCAGGACTGTGCCTCCATAATTTGG
TCATTTGGCAGCCCCTGTTTTCTGCTGTTTACAACATCACCAGTGCCACGTCATGAGCGTCAAAGAAAATGCCTAGAGATATTTCAAGCT
CATGTCATTATGACATTTCTTAAAACTTTATTAAAAGAATGAGTGAAGTATTGCTGAAAAGTGGAAATTCGGTTGGGTACCATGCTTTTT
CTCCCCTTCACGTTTGCAGTTGATGTGTCTTTTTTTTTTTTTTTAATGTATCTTAAAGGACATAAAATTTAAAAACTTAAATATTGTAAT
ATGACAGATAACCTAATAATTGTATCTACATTAAAATGACAAACATGATACTGCTGCTTGTCAAATAAAAAAAAAATAAAGAAATAGAAT
GCCTTTTTTATGTGGATGGAGTATCAGGTTGACCACAAAATATATTGACTCAAAGCAGCTAATGCATCTTTAGTTGCGTTTTTATCTGAA
TGGTTTAATTCACTTGTACTCCTATTTAAATCCTACATGAAAAATGTCTAGATTATTGTTCTTGACTGCATAGGACTGCATTCAGCATAA
AGAATGCTTTATTTTTATGGATTAGATATATTGGATCTAAACATTTTGAATCTTGAAGATGTAATTCCATCAGCAGTTTCTGGTGGTGTG
CTACTCCACAGACATCGCAGAGTGTGAGCAGGATGCTTGGTGACCTCAAGTCTGGCACAGAGAGAGCTTTTCATTCAAAAGTTGTCTTTC
TTCGGTTGCATAATCCATTAATTCTAGCATAGACTAGTACCCTAGCTCTGTGGCCTTCCCTGAGTCTTAGGAAATCTATGATACCAACAT
ATTCCTTCTATATGCCTCCCCTACCTGTTACCCTTACAACCCTCCTCCAACAGTTTAGATACTAGAGTCACTCTCATCAATCACAGATGT
GCTTAGCAATGCATAACCTAAATACTTTTTTAAAAAAGAAAATTGTACATTGTACTGGGTGCCACATATATAAATCCCATTATTTTGTTT
ATTTTATATATATATATATATATAATATATATATATATATATCTCAACAGCAGTGTTAAGAGTACTGCGATCTATTATCATATTTATTGT
CTATCCACACCATCACCACCACCACCACACCCCTCCTCCCTCAACATACAATTTTTCTTTATTTTAAAAAAAATAAGAGACGGGGTTTCG
CCATGTTTCCCAGGCTAGTCTGGAACTTCTGGCCTCAAGCAATCCTATCTCTGTCTCCCAAAGTGCTGGGATTACAAGCATGAGCCACTG
CATCCATCCAACACAAAATTTTTAAAATCGGAATATTTTAAAGCAAATCACACAAATTATTTCACTTATAATACTTCAGTAAGGCCTTTA
AAAAATCCACAGTGATATTATTACTCCTAACAAAAACAATAATTACTTAGTATCATCTAATATGTGGTTCATATTTAAATTTGTTGTTTT
GAGATGGGTCTTACAATTGGTTTATTCAATTGCATTTTTTCTAACTCGTGTCTCAAGTGTTTTAAAAATCTACTGAACTTATAATGACTT
ATATAATGTATTTCTCATTTTACCTTTCTTCCAAAAGAGGAAATAATGGCAAACCATATAATATTGTACATTCACTGTCAAAAAGCAAAC

>In-frame_PARD3_ENST00000374773_chr10_34985246_-_CUL2_ENST00000374746_chr10_35360267_-_4451nt
GCGGCCCCGAGCGAGCGCCAGCGCCACACAGCCCCGGGCAGCCGCCGGCGAGCGCGCCGCGACGCCGAACAGGTGGCCGGAGGCTGCGGG
CGCCGCGGCGGGGAGAGGCGAGGCAAGCCCCGGGCGAAGCGAGGCGAGGCGAGGGCGGCCGGGCCGGGCATGCGAGCTGAGCGGCCCCCC
GGCGTCGCCGCCGCCTGCCCGCGCCCCTAGCCGCCCGCGCGCCCGAGTCCCCAGCGGCTCCTCCGCGCCCAGCGTCCTCGGTCCCGGCCT
CGGCTGCTCCGGCTGCGCTCGGCGAGGGGCGCGGGCCCGCCCGCGGCGGCGGCGGCATGAAAGTGACCGTGTGCTTCGGACGGACCCGGG
TGGTCGTGCCGTGCGGGGACGGCCACATGAAAGTTTTCAGCCTCATCCAGCAGGCGGTGACCCGCTACCGGAAGGCCATCGCCAAGGATC
CAAACTACTGGATACAGGTGCATCGCTTGGAACATGGAGATGGAGGAATACTAGACCTTGATGACATTCTTTGTGATGTAGCAGACGATA
AAGACAGAATTTCAACACTACACTTGCACAATGTCTTTGAAACCAAGAGTAGTAGATTTTGATGAAACATGGAACAAACTTTTGACGACA
ATAAAAGCCGTGGTCATGTTGGAATACGTCGAAAGAGCAACATGGAATGACCGTTTCTCAGATATCTATGCTTTATGTGTGGCCTATCCT
GAACCCCTTGGAGAAAGACTTTATACAGAAACTAAGATTTTTTTGGAAAATCATGTTCGGCATTTGCATAAGAGAGTTTTGGAGTCAGAA
GAACAAGTACTTGTTATGTATCATAGGTACTGGGAAGAATACAGCAAGGGTGCAGACTATATGGACTGCTTATATAGGTATCTCAACACC
CAGTTTATTAAAAAGAATAAATTAACAGAAGCGGACCTTCAGTATGGCTATGGTGGTGTAGATATGAATGAACCACTTATGGAAATAGGA
GAGCTAGCATTGGATATGTGGAGGAAATTGATGGTTGAACCACTTCAGGCCATCCTTATCCGAATGCTGCTCCGAGAAATCAAAAATGAT
CGTGGTGGAGAAGACCCAAACCAGAAAGTAATCCATGGGGTTATTAACTCCTTTGTTCATGTTGAACAGTATAAGAAAAAATTCCCCTTA
AAGTTTTATCAGGAAATTTTTGAGTCTCCCTTTCTGACTGAAACAGGAGAGTATTACAAACAAGAAGCTTCAAATTTATTACAAGAATCA
AACTGCTCACAGTATATGGAAAAGGTTCTAGGTAGATTAAAAGATGAAGAAATTCGATGTCGAAAATACCTACATCCAAGTTCATATACT
AAGGTGATTCATGAATGTCAACAACGAATGGTAGCAGACCACTTACAGTTTTTACATGCAGAATGTCATAATATAATTCGACAAGAGAAA
AAAAATGACATGGCAAATATGTACGTCTTACTCCGTGCTGTGTCCACTGGTTTACCTCATATGATTCAGGAGCTGCAAAACCACATCCAT
GATGAGGGCCTTCGAGCAACCAGCAACCTTACTCAGGAAAACATGCCAACACTATTTGTGGAGTCAGTTTTGGAAGTGCATGGTAAATTT
GTTCAGCTTATCAACACTGTTTTGAATGGTGATCAGCATTTTATGAGTGCGTTGGATAAGGCCCTTACGTCAGTTGTAAATTACAGAGAA
CCTAAGTCTGTTTGCAAAGCACCTGAACTGCTTGCTAAGTACTGTGACAACTTACTGAAGAAGTCAGCGAAAGGGATGACAGAGAATGAA
GTGGAAGACAGGCTCACGAGCTTCATCACAGTGTTCAAATACATTGATGACAAGGACGTCTTTCAAAAGTTCTACGCAAGAATGCTGGCA
AAACGTTTAATTCATGGGTTATCCATGTCTATGGACTCTGAAGAAGCCATGATCAACAAATTAAAGCAAGCCTGTGGTTATGAGTTTACC
AGCAAGCTACATCGGATGTATACAGATATGAGTGTCAGCGCTGATCTCAACAATAAGTTCAACAATTTTATCAAAAACCAAGACACAGTA
ATAGATTTGGGAATTAGTTTTCAAATATATGTTCTACAGGCTGGTGCGTGGCCTCTTACTCAGGCTCCTTCATCTACGTTTGCAATTCCC
CAGGAATTAGAAAAAAGTGTACAGATGTTTGAATTATTTTATAGCCAACATTTCAGTGGAAGGAAACTTACATGGTTACATTATCTGTGT
ACAGGTGAAGTTAAAATGAACTATTTGGGCAAACCATATGTAGCCATGGTTACAACATACCAAATGGCAGTTCTTCTTGCCTTTAACAAC
AGTGAAACTGTCAGTTATAAAGAGCTTCAGGACAGCACTCAGATGAATGAAAAGGAACTGACAAAAACAATCAAATCATTACTTGATGTG
AAAATGATTAACCATGATTCAGAAAAGGAAGATATTGATGCAGAATCTTCGTTTTCATTAAATATGAACTTTAGCAGTAAAAGAACAAAA
TTTAAAATTACTACATCAATGCAGAAAGACACACCACAAGTGATTAGCCAGTCAAGAGCTAGGTTTAATCCCAGTATCAGCATGATTAAG
AAGTGTATTGAAGTTCTGATAGACAAACAATACATAGAACGCAGCCAGGCGTCGGCAGATGAATACAGCTACGTCGCGTGATGTCGCTCT
CCTCCAGCGTGGTGTGAGAAGATCATTGCCATCACCATTTGGTGTGTTCCTGTGGGAAAAAGCAGGACTGTGCCTCCATAATTTGGTCAT
TTGGCAGCCCCTGTTTTCTGCTGTTTACAACATCACCAGTGCCACGTCATGAGCGTCAAAGAAAATGCCTAGAGATATTTCAAGCTCATG
TCATTATGACATTTCTTAAAACTTTATTAAAAGAATGAGTGAAGTATTGCTGAAAAGTGGAAATTCGGTTGGGTACCATGCTTTTTCTCC
CCTTCACGTTTGCAGTTGATGTGTCTTTTTTTTTTTTTTTAATGTATCTTAAAGGACATAAAATTTAAAAACTTAAATATTGTAATATGA
CAGATAACCTAATAATTGTATCTACATTAAAATGACAAACATGATACTGCTGCTTGTCAAATAAAAAAAAAATAAAGAAATAGAATGCCT
TTTTTATGTGGATGGAGTATCAGGTTGACCACAAAATATATTGACTCAAAGCAGCTAATGCATCTTTAGTTGCGTTTTTATCTGAATGGT
TTAATTCACTTGTACTCCTATTTAAATCCTACATGAAAAATGTCTAGATTATTGTTCTTGACTGCATAGGACTGCATTCAGCATAAAGAA
TGCTTTATTTTTATGGATTAGATATATTGGATCTAAACATTTTGAATCTTGAAGATGTAATTCCATCAGCAGTTTCTGGTGGTGTGCTAC
TCCACAGACATCGCAGAGTGTGAGCAGGATGCTTGGTGACCTCAAGTCTGGCACAGAGAGAGCTTTTCATTCAAAAGTTGTCTTTCTTCG
GTTGCATAATCCATTAATTCTAGCATAGACTAGTACCCTAGCTCTGTGGCCTTCCCTGAGTCTTAGGAAATCTATGATACCAACATATTC
CTTCTATATGCCTCCCCTACCTGTTACCCTTACAACCCTCCTCCAACAGTTTAGATACTAGAGTCACTCTCATCAATCACAGATGTGCTT
AGCAATGCATAACCTAAATACTTTTTTAAAAAAGAAAATTGTACATTGTACTGGGTGCCACATATATAAATCCCATTATTTTGTTTATTT
TATATATATATATATATATAATATATATATATATATATCTCAACAGCAGTGTTAAGAGTACTGCGATCTATTATCATATTTATTGTCTAT
CCACACCATCACCACCACCACCACACCCCTCCTCCCTCAACATACAATTTTTCTTTATTTTAAAAAAAATAAGAGACGGGGTTTCGCCAT
GTTTCCCAGGCTAGTCTGGAACTTCTGGCCTCAAGCAATCCTATCTCTGTCTCCCAAAGTGCTGGGATTACAAGCATGAGCCACTGCATC
CATCCAACACAAAATTTTTAAAATCGGAATATTTTAAAGCAAATCACACAAATTATTTCACTTATAATACTTCAGTAAGGCCTTTAAAAA
ATCCACAGTGATATTATTACTCCTAACAAAAACAATAATTACTTAGTATCATCTAATATGTGGTTCATATTTAAATTTGTTGTTTTGAGA
TGGGTCTTACAATTGGTTTATTCAATTGCATTTTTTCTAACTCGTGTCTCAAGTGTTTTAAAAATCTACTGAACTTATAATGACTTATAT
AATGTATTTCTCATTTTACCTTTCTTCCAAAAGAGGAAATAATGGCAAACCATATAATATTGTACATTCACTGTCAAAAAGCAAACCCTT


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FusionGenePPI for PARD3_CUL2


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check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
PARD3YWHAB, YWHAG, SFN, ECT2, F11R, JAM2, JAM3, PVRL3, PARD6A, PARD6B, PARD6G, PRKCI, PRKCZ, YWHAZ, YWHAH, DCAF7, PNMA1, RASSF8, CCDC88A, PNMA2, LLGL1, SIAH1, HSPA8, HSPA6, HSPD1, PSME3, PSME2, RPS3, RPS18, PFKP, KPNA4, ANP32E, TJP1, VHL, ARHGAP17, AMOT, YWHAE, GAB1, MARK2, INADL, AMOTL2, LATS1, LATS2, YAP1, RASSF7, PSMC3, TP53BP2, RASSF9, RASSF10, SMAD7, SMAD4, SMAD1, SMAD2, SMAD3, CEP19, TMEM17, VAPA, MMGT1, CTNNB1, PPP1CA, CDH1, TRIM25CUL2RNF7, VHL, P4HB, CAB39, TFE3, TIMM13, STOM, RPL35P5, PFKFB3, RNMTL1, KCTD5, CMBL, DLG3, CAND1, RBX1, TCEB2, TCEB1, DCUN1D1, SAP130, ASB4, COPS5, COPS6, TCEAL1, HIF1A, COMMD1, KLHDC10, SH3GLB1, COPS3, KEAP1, ARID1B, ARID1A, COPS2, UBE2D1, RELA, DNMT3B, ARNT, NSFL1C, FAF2, FAF1, UBXN7, UBXN1, VCP, KAT2A, ADRB2, ASB2, MED8, FBXW8, GLMN, PFDN5, SKP2, SQSTM1, NEDD8, PRAME, BCL2L11, TOP2A, ZYG11B, ZER1, FEM1B, APPBP2, KLHDC2, KLHDC3, PCMTD2, CUL5, ABCF1, ACLY, ACTA2, ACTB, ACTBL2, AGL, AIFM1, AKAP8L, FBF1, ALDOA, ANKRD39, ANXA2, ANXA2P2, APOD, ASPRV1, BAG4, BOLA2, BOLA2B, BRAP, BTG3, EDRF1, C11orf70, C14orf166, C1QBP, RTCB, VWA7, YAE1D1, DFFB, CARM1, CASP14, CDKN2A, CEP152, CIRBP, CLTC, COPS4, COPS7A, COPS7B, COPS8, LUC7L3, YBX3, CSTA, CTPS1, CTSD, CUL4B, DAZAP1, DCD, DDX1, DDX17, DDX56, DDX3X, DDX5, DERL2, DHX15, DHX9, DNAJA1, DNAJB6, DNAJC10, DSG1, DSP, EEF1A1, EEF1A2, EEF1B2, EEF1D, EEF1G, EGFLAM, AGO2, EIF5A, ELAVL1, EMD, ENO1, ENO2, EWSR1, FAM103A1, FAM98A, FEM1A, FEM1C, FLG, FLG2, FUS, GAPDH, GDPD3, GLDC, GPS1, GRSF1, GSTP1, HIST1H1C, HIST2H2BE, HNRNPA0, HNRNPA1, HNRNPA2B1, HNRNPA3, HNRNPAB, HNRNPC, HNRNPCL1, HNRNPD, HNRNPF, HNRNPH1, HNRNPH3, HNRNPK, HNRNPM, HNRNPR, HNRNPU, HNRNPUL1, HNRNPDL, HRNR, HSP90AA1, HSP90AA2P, HSP90AB1, HSP90AB2P, HSP90B1, HSPA1A, HSPA1B, HSPA1L, HSPA5, HSPA7, HSPA8, HSPA9, TRMT112, HSPD1, IGF2BP1, IGKV4-1, ILF2, ILF3, IRS4, JUP, KDELC1, KHSRP, KLC3, PPP1R21, KRT1, KRT10, KRT13, KRT14, KRT16, KRT2, KRT24, KRT5, KRT6A, KRT6C, KRT71, KRT75, KRT76, KRT78, KRT9, LARP1, LGALS3BP, IGHV3OR15-7, LOXL1, LRRC14, MCM3, MLPH, MORC2, MRTO4, MTHFD1, MTHFSD, MYEOV2, NAP1L1, NCL, NFRKB, NKAPL, NONO, NPM1, NUCB2, NUDT1, NUP214, NUP88, PABPC1, PABPC4, PABPN1, PARP14, PCBP1, PCBP2, PCMT1, PCNA, PDCD6, PEPD, PHGDH, PKM, PLOD1, POLR2A, POP7, PPFIA1, LRR1, PRDX1, PRDX2, PRDX3, PRDX4, PRMT1, PRPF39, PSMD4, PTOV1, QPCT, RANBP2, RBM14, RBM4, RBM3, RCBTB1, RNF187, RNMT, RNPS1, RPL10P16, RPL11, RPL12, RPL13, RPL13P12, RPL14, RPL15, RPL18, RPL19, RPL21P19, RPL21, RPL21P16, RPL22, RPL23, RPL23A, RPL24, RPL27, RPL27A, RPL28, RPL29P11, RPL29P30, RPL3, RPL31, RPL36, HNRNPH2, RPL36AP37, RPL38, RPL4, RPL5, RPL6, RPL7, RPL7P32, RPL7AP9, RPL7AP27, RPL8, RPL9, RPLP0, RPLP1, RPLP2, RPS13, RPS14, RPS15A, RPS16, RPS18, RPS2, RPS20, RPS23, RPS24, RPS25, RPS27, RPS3, RPS3A, RPS4X, RPS6, RPS8, RPS9, RPSAP12, RPSAP55, S100A9, SAMHD1, SDHA, SDHB, SEC23A, SERPINB12, SERPINB3, SERPINB4, SF3B3, SRSF1, SRSF2, SRSF3, SRSF6, SRSF7, SLC16A1, SLC25A3, SLC25A5, SMAD6, SMC3, SMPD4, SNRNP200, SNRNP70, SNRPA, SNRPB, SNRPC, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF, SNW1, SSB, SYNCRIP, TAF15, TBC1D15, TBC1D17, TBC1D4, TCEB1P3, TFG, ALYREF, TIA1, TIAL1, TMCC3, TNRC6B, TRA2B, TRIM28, TRIM44, TRIM9, TTN, TUBA1C, TUBA4A, TUBB, TUBB1, TUBB2A, TUBB4B, TUFM, TXN, UBC, UBE2M, UBR1, USP25, WDR77, YBX1, YWHAQ, YWHAZ, ZCCHC11, ZRANB3, HIST1H4J, HIST4H4, HIST1H4E, HIST1H4H, HIST1H4K, HIST2H4A, HIST1H4D, HIST1H4F, HIST2H4B, HIST1H4C, HIST1H4B, HIST1H4I, HIST1H4L, HIST1H4A, PTPN14, LAGE3, OSGEP, CISH, GNB2L1, KLF4, MKNK2, RFWD2, DCUN1D2, DCUN1D3, DCUN1D4, DCUN1D5, PLK1, FBXL2, CCDC22, AR, DLC1, ATP6V1B2, CTNNA1, DPYSL3, MSH2, NARS, ST13, XRCC5, XRCC6, KPNB1, NDRG1, CSNK1E, SHFM1, SHMT2, MOV10, NXF1, CDC34, SENP8, ARIH1, MRM1, SKAP1, TSGA10IP, RHOB, UNK, ATP6V1D, CIAPIN1, CUL3, NTRK1, TARDBP, EPOR, SLBP, PYCARD, OXT, PRAMEF17, IKZF1, AVP, SYCE3, RGS20, BRCA1


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgenePARD3chr10:34985246chr10:35360267ENST00000340077-221935_1356741032FRMD4A
HgenePARD3chr10:34985246chr10:35360267ENST00000346874-224935_1356741320FRMD4A
HgenePARD3chr10:34985246chr10:35360267ENST00000350537-224935_1356741311FRMD4A
HgenePARD3chr10:34985246chr10:35360267ENST00000374776-220935_135674989FRMD4A
HgenePARD3chr10:34985246chr10:35360267ENST00000374788-225935_1356741354FRMD4A
HgenePARD3chr10:34985246chr10:35360267ENST00000374789-225935_1356741357FRMD4A
HgenePARD3chr10:34985246chr10:35360267ENST00000374794-221935_1356741245FRMD4A
HgenePARD3chr10:34985246chr10:35360267ENST00000545260-223935_1356741267FRMD4A
HgenePARD3chr10:34985246chr10:35360267ENST00000545693-224935_1356741341FRMD4A
HgenePARD3chr10:34985246chr10:35360267ENST00000340077-221712_936741032PRKCI and PRKCZ
HgenePARD3chr10:34985246chr10:35360267ENST00000346874-224712_936741320PRKCI and PRKCZ
HgenePARD3chr10:34985246chr10:35360267ENST00000350537-224712_936741311PRKCI and PRKCZ
HgenePARD3chr10:34985246chr10:35360267ENST00000374776-220712_93674989PRKCI and PRKCZ
HgenePARD3chr10:34985246chr10:35360267ENST00000374788-225712_936741354PRKCI and PRKCZ
HgenePARD3chr10:34985246chr10:35360267ENST00000374789-225712_936741357PRKCI and PRKCZ
HgenePARD3chr10:34985246chr10:35360267ENST00000374794-221712_936741245PRKCI and PRKCZ
HgenePARD3chr10:34985246chr10:35360267ENST00000545260-223712_936741267PRKCI and PRKCZ
HgenePARD3chr10:34985246chr10:35360267ENST00000545693-224712_936741341PRKCI and PRKCZ


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for PARD3_CUL2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for PARD3_CUL2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneCUL2C0021390Inflammatory Bowel Diseases1CTD_human