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Fusion gene ID: 25875 |
FusionGeneSummary for PAN3_FLT3 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PAN3_FLT3 | Fusion gene ID: 25875 | Hgene | Tgene | Gene symbol | PAN3 | FLT3 | Gene ID | 255967 | 2322 |
| Gene name | poly(A) specific ribonuclease subunit PAN3 | fms related tyrosine kinase 3 | |
| Synonyms | - | CD135|FLK-2|FLK2|STK1 | |
| Cytomap | 13q12.2 | 13q12.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | PAN2-PAN3 deadenylation complex subunit PAN3PAB-dependent poly(A)-specific ribonuclease subunit 3PAB-dependent poly(A)-specific ribonuclease subunit PAN3PAB1P-dependent poly(A)-nucleasePAB1P-dependent poly(A)-specific ribonucleasePABP-dependent poly( | receptor-type tyrosine-protein kinase FLT3CD135 antigenFL cytokine receptorfetal liver kinase 2fms-like tyrosine kinase 3growth factor receptor tyrosine kinase type IIIstem cell tyrosine kinase 1 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q58A45 | P36888 | |
| Ensembl transtripts involved in fusion gene | ENST00000380958, ENST00000399613, ENST00000282391, ENST00000483842, | ENST00000241453, ENST00000380982, ENST00000537084, ENST00000469894, | |
| Fusion gene scores | * DoF score | 10 X 7 X 7=490 | 2 X 3 X 3=18 |
| # samples | 11 | 4 | |
| ** MAII score | log2(11/490*10)=-2.15527822547791 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(4/18*10)=1.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: PAN3 [Title/Abstract] AND FLT3 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Oncogene involved fusion gene, in-frame and retained their domain. Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. Tumor suppressor gene involved fusion gene, retained protein feature but frameshift. DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain. Kinase involved fusion gene, inframe and retained kinase domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | FLT3 | GO:0030097 | hemopoiesis | 7507245 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | COAD | TCGA-AA-3712-01A | PAN3 | chr13 | 28752072 | + | FLT3 | chr13 | 28644749 | - |
| TCGA | LD | LAML | TCGA-AB-2853-03A | PAN3 | chr13 | 28794515 | + | FLT3 | chr13 | 28644749 | - |
| TCGA | RV | SARC | TCGA-HS-A5NA-01A | PAN3 | chr13 | 28713224 | + | FLT3 | chr13 | 28644749 | - |
| TCGA | LD | SARC | TCGA-HS-A5NA-01A | PAN3 | chr13 | 28713224 | + | FLT3 | chr13 | 28636206 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000380958 | ENST00000241453 | PAN3 | chr13 | 28752072 | + | FLT3 | chr13 | 28644749 | - |
| Frame-shift | ENST00000380958 | ENST00000380982 | PAN3 | chr13 | 28752072 | + | FLT3 | chr13 | 28644749 | - |
| Frame-shift | ENST00000380958 | ENST00000537084 | PAN3 | chr13 | 28752072 | + | FLT3 | chr13 | 28644749 | - |
| 5CDS-intron | ENST00000380958 | ENST00000469894 | PAN3 | chr13 | 28752072 | + | FLT3 | chr13 | 28644749 | - |
| Frame-shift | ENST00000399613 | ENST00000241453 | PAN3 | chr13 | 28752072 | + | FLT3 | chr13 | 28644749 | - |
| Frame-shift | ENST00000399613 | ENST00000380982 | PAN3 | chr13 | 28752072 | + | FLT3 | chr13 | 28644749 | - |
| Frame-shift | ENST00000399613 | ENST00000537084 | PAN3 | chr13 | 28752072 | + | FLT3 | chr13 | 28644749 | - |
| 5CDS-intron | ENST00000399613 | ENST00000469894 | PAN3 | chr13 | 28752072 | + | FLT3 | chr13 | 28644749 | - |
| intron-3CDS | ENST00000282391 | ENST00000241453 | PAN3 | chr13 | 28752072 | + | FLT3 | chr13 | 28644749 | - |
| intron-3CDS | ENST00000282391 | ENST00000380982 | PAN3 | chr13 | 28752072 | + | FLT3 | chr13 | 28644749 | - |
| intron-3CDS | ENST00000282391 | ENST00000537084 | PAN3 | chr13 | 28752072 | + | FLT3 | chr13 | 28644749 | - |
| intron-intron | ENST00000282391 | ENST00000469894 | PAN3 | chr13 | 28752072 | + | FLT3 | chr13 | 28644749 | - |
| intron-3CDS | ENST00000483842 | ENST00000241453 | PAN3 | chr13 | 28752072 | + | FLT3 | chr13 | 28644749 | - |
| intron-3CDS | ENST00000483842 | ENST00000380982 | PAN3 | chr13 | 28752072 | + | FLT3 | chr13 | 28644749 | - |
| intron-3CDS | ENST00000483842 | ENST00000537084 | PAN3 | chr13 | 28752072 | + | FLT3 | chr13 | 28644749 | - |
| intron-intron | ENST00000483842 | ENST00000469894 | PAN3 | chr13 | 28752072 | + | FLT3 | chr13 | 28644749 | - |
| In-frame | ENST00000380958 | ENST00000241453 | PAN3 | chr13 | 28794515 | + | FLT3 | chr13 | 28644749 | - |
| In-frame | ENST00000380958 | ENST00000380982 | PAN3 | chr13 | 28794515 | + | FLT3 | chr13 | 28644749 | - |
| In-frame | ENST00000380958 | ENST00000537084 | PAN3 | chr13 | 28794515 | + | FLT3 | chr13 | 28644749 | - |
| 5CDS-intron | ENST00000380958 | ENST00000469894 | PAN3 | chr13 | 28794515 | + | FLT3 | chr13 | 28644749 | - |
| In-frame | ENST00000399613 | ENST00000241453 | PAN3 | chr13 | 28794515 | + | FLT3 | chr13 | 28644749 | - |
| In-frame | ENST00000399613 | ENST00000380982 | PAN3 | chr13 | 28794515 | + | FLT3 | chr13 | 28644749 | - |
| In-frame | ENST00000399613 | ENST00000537084 | PAN3 | chr13 | 28794515 | + | FLT3 | chr13 | 28644749 | - |
| 5CDS-intron | ENST00000399613 | ENST00000469894 | PAN3 | chr13 | 28794515 | + | FLT3 | chr13 | 28644749 | - |
| intron-3CDS | ENST00000282391 | ENST00000241453 | PAN3 | chr13 | 28794515 | + | FLT3 | chr13 | 28644749 | - |
| intron-3CDS | ENST00000282391 | ENST00000380982 | PAN3 | chr13 | 28794515 | + | FLT3 | chr13 | 28644749 | - |
| intron-3CDS | ENST00000282391 | ENST00000537084 | PAN3 | chr13 | 28794515 | + | FLT3 | chr13 | 28644749 | - |
| intron-intron | ENST00000282391 | ENST00000469894 | PAN3 | chr13 | 28794515 | + | FLT3 | chr13 | 28644749 | - |
| intron-3CDS | ENST00000483842 | ENST00000241453 | PAN3 | chr13 | 28794515 | + | FLT3 | chr13 | 28644749 | - |
| intron-3CDS | ENST00000483842 | ENST00000380982 | PAN3 | chr13 | 28794515 | + | FLT3 | chr13 | 28644749 | - |
| intron-3CDS | ENST00000483842 | ENST00000537084 | PAN3 | chr13 | 28794515 | + | FLT3 | chr13 | 28644749 | - |
| intron-intron | ENST00000483842 | ENST00000469894 | PAN3 | chr13 | 28794515 | + | FLT3 | chr13 | 28644749 | - |
| In-frame | ENST00000380958 | ENST00000241453 | PAN3 | chr13 | 28713224 | + | FLT3 | chr13 | 28644749 | - |
| In-frame | ENST00000380958 | ENST00000380982 | PAN3 | chr13 | 28713224 | + | FLT3 | chr13 | 28644749 | - |
| In-frame | ENST00000380958 | ENST00000537084 | PAN3 | chr13 | 28713224 | + | FLT3 | chr13 | 28644749 | - |
| 5CDS-intron | ENST00000380958 | ENST00000469894 | PAN3 | chr13 | 28713224 | + | FLT3 | chr13 | 28644749 | - |
| 5UTR-3CDS | ENST00000399613 | ENST00000241453 | PAN3 | chr13 | 28713224 | + | FLT3 | chr13 | 28644749 | - |
| 5UTR-3CDS | ENST00000399613 | ENST00000380982 | PAN3 | chr13 | 28713224 | + | FLT3 | chr13 | 28644749 | - |
| 5UTR-3CDS | ENST00000399613 | ENST00000537084 | PAN3 | chr13 | 28713224 | + | FLT3 | chr13 | 28644749 | - |
| 5UTR-intron | ENST00000399613 | ENST00000469894 | PAN3 | chr13 | 28713224 | + | FLT3 | chr13 | 28644749 | - |
| intron-3CDS | ENST00000282391 | ENST00000241453 | PAN3 | chr13 | 28713224 | + | FLT3 | chr13 | 28644749 | - |
| intron-3CDS | ENST00000282391 | ENST00000380982 | PAN3 | chr13 | 28713224 | + | FLT3 | chr13 | 28644749 | - |
| intron-3CDS | ENST00000282391 | ENST00000537084 | PAN3 | chr13 | 28713224 | + | FLT3 | chr13 | 28644749 | - |
| intron-intron | ENST00000282391 | ENST00000469894 | PAN3 | chr13 | 28713224 | + | FLT3 | chr13 | 28644749 | - |
| intron-3CDS | ENST00000483842 | ENST00000241453 | PAN3 | chr13 | 28713224 | + | FLT3 | chr13 | 28644749 | - |
| intron-3CDS | ENST00000483842 | ENST00000380982 | PAN3 | chr13 | 28713224 | + | FLT3 | chr13 | 28644749 | - |
| intron-3CDS | ENST00000483842 | ENST00000537084 | PAN3 | chr13 | 28713224 | + | FLT3 | chr13 | 28644749 | - |
| intron-intron | ENST00000483842 | ENST00000469894 | PAN3 | chr13 | 28713224 | + | FLT3 | chr13 | 28644749 | - |
| Frame-shift | ENST00000380958 | ENST00000241453 | PAN3 | chr13 | 28713224 | + | FLT3 | chr13 | 28636206 | - |
| Frame-shift | ENST00000380958 | ENST00000380982 | PAN3 | chr13 | 28713224 | + | FLT3 | chr13 | 28636206 | - |
| Frame-shift | ENST00000380958 | ENST00000537084 | PAN3 | chr13 | 28713224 | + | FLT3 | chr13 | 28636206 | - |
| 5CDS-intron | ENST00000380958 | ENST00000469894 | PAN3 | chr13 | 28713224 | + | FLT3 | chr13 | 28636206 | - |
| 5UTR-3CDS | ENST00000399613 | ENST00000241453 | PAN3 | chr13 | 28713224 | + | FLT3 | chr13 | 28636206 | - |
| 5UTR-3CDS | ENST00000399613 | ENST00000380982 | PAN3 | chr13 | 28713224 | + | FLT3 | chr13 | 28636206 | - |
| 5UTR-3CDS | ENST00000399613 | ENST00000537084 | PAN3 | chr13 | 28713224 | + | FLT3 | chr13 | 28636206 | - |
| 5UTR-intron | ENST00000399613 | ENST00000469894 | PAN3 | chr13 | 28713224 | + | FLT3 | chr13 | 28636206 | - |
| intron-3CDS | ENST00000282391 | ENST00000241453 | PAN3 | chr13 | 28713224 | + | FLT3 | chr13 | 28636206 | - |
| intron-3CDS | ENST00000282391 | ENST00000380982 | PAN3 | chr13 | 28713224 | + | FLT3 | chr13 | 28636206 | - |
| intron-3CDS | ENST00000282391 | ENST00000537084 | PAN3 | chr13 | 28713224 | + | FLT3 | chr13 | 28636206 | - |
| intron-intron | ENST00000282391 | ENST00000469894 | PAN3 | chr13 | 28713224 | + | FLT3 | chr13 | 28636206 | - |
| intron-3CDS | ENST00000483842 | ENST00000241453 | PAN3 | chr13 | 28713224 | + | FLT3 | chr13 | 28636206 | - |
| intron-3CDS | ENST00000483842 | ENST00000380982 | PAN3 | chr13 | 28713224 | + | FLT3 | chr13 | 28636206 | - |
| intron-3CDS | ENST00000483842 | ENST00000537084 | PAN3 | chr13 | 28713224 | + | FLT3 | chr13 | 28636206 | - |
| intron-intron | ENST00000483842 | ENST00000469894 | PAN3 | chr13 | 28713224 | + | FLT3 | chr13 | 28636206 | - |
Top |
FusionProtFeatures for PAN3_FLT3 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| PAN3 | FLT3 |
| Tyrosine-protein kinase that acts as cell-surfacereceptor for the cytokine FLT3LG and regulates differentiation,proliferation and survival of hematopoietic progenitor cells andof dendritic cells. Promotes phosphorylation of SHC1 and AKT1, andactivation of the downstream effector MTOR. Promotes activation ofRAS signaling and phosphorylation of downstream kinases, includingMAPK1/ERK2 and/or MAPK3/ERK1. Promotes phosphorylation of FES,FER, PTPN6/SHP, PTPN11/SHP-2, PLCG1, and STAT5A and/or STAT5B.Activation of wild-type FLT3 causes only marginal activation ofSTAT5A or STAT5B. Mutations that cause constitutive kinaseactivity promote cell proliferation and resistance to apoptosisvia the activation of multiple signaling pathways.{ECO:0000269|PubMed:10080542, ECO:0000269|PubMed:11090077,ECO:0000269|PubMed:14504097, ECO:0000269|PubMed:16266983,ECO:0000269|PubMed:16627759, ECO:0000269|PubMed:18490735,ECO:0000269|PubMed:20111072, ECO:0000269|PubMed:21067588,ECO:0000269|PubMed:21262971, ECO:0000269|PubMed:21516120,ECO:0000269|PubMed:7507245}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | PAN3 | chr13:28794515 | chr13:28644749 | ENST00000380958 | + | 6 | 19 | 284_299 | 333 | 888 | Motif | PABPC-interacting motif-2 (PAM-2) |
| Hgene | PAN3 | chr13:28713224 | chr13:28644749 | ENST00000380958 | + | 1 | 19 | 43_71 | 143 | 888 | Zinc finger | C3H1-type |
| Hgene | PAN3 | chr13:28794515 | chr13:28644749 | ENST00000380958 | + | 6 | 19 | 43_71 | 333 | 888 | Zinc finger | C3H1-type |
| Hgene | PAN3 | chr13:28794515 | chr13:28644749 | ENST00000399613 | + | 5 | 18 | 43_71 | 133 | 688 | Zinc finger | C3H1-type |
| Tgene | >FLT3 | chr13:28713224 | chr13:28644749 | ENST00000241453 | - | 0 | 24 | 253_343 | 14 | 994 | Domain | Note=Ig-like C2-type |
| Tgene | >FLT3 | chr13:28713224 | chr13:28644749 | ENST00000241453 | - | 0 | 24 | 610_943 | 14 | 994 | Domain | Protein kinase |
| Tgene | >FLT3 | chr13:28713224 | chr13:28644749 | ENST00000537084 | - | 0 | 23 | 253_343 | 14 | 953 | Domain | Note=Ig-like C2-type |
| Tgene | >FLT3 | chr13:28713224 | chr13:28644749 | ENST00000537084 | - | 0 | 23 | 610_943 | 14 | 953 | Domain | Protein kinase |
| Tgene | >FLT3 | chr13:28794515 | chr13:28644749 | ENST00000241453 | - | 0 | 24 | 253_343 | 14 | 994 | Domain | Note=Ig-like C2-type |
| Tgene | >FLT3 | chr13:28794515 | chr13:28644749 | ENST00000241453 | - | 0 | 24 | 610_943 | 14 | 994 | Domain | Protein kinase |
| Tgene | >FLT3 | chr13:28794515 | chr13:28644749 | ENST00000537084 | - | 0 | 23 | 253_343 | 14 | 953 | Domain | Note=Ig-like C2-type |
| Tgene | >FLT3 | chr13:28794515 | chr13:28644749 | ENST00000537084 | - | 0 | 23 | 610_943 | 14 | 953 | Domain | Protein kinase |
| Tgene | >FLT3 | chr13:28713224 | chr13:28644749 | ENST00000241453 | - | 0 | 24 | 616_624 | 14 | 994 | Nucleotide binding | ATP |
| Tgene | >FLT3 | chr13:28713224 | chr13:28644749 | ENST00000537084 | - | 0 | 23 | 616_624 | 14 | 953 | Nucleotide binding | ATP |
| Tgene | >FLT3 | chr13:28794515 | chr13:28644749 | ENST00000241453 | - | 0 | 24 | 616_624 | 14 | 994 | Nucleotide binding | ATP |
| Tgene | >FLT3 | chr13:28794515 | chr13:28644749 | ENST00000537084 | - | 0 | 23 | 616_624 | 14 | 953 | Nucleotide binding | ATP |
| Tgene | >FLT3 | chr13:28713224 | chr13:28644749 | ENST00000241453 | - | 0 | 24 | 591_597 | 14 | 994 | Region | Note=Important for normal regulation of the kinase activity and for maintaining the kinase in an inactive state in the absence of bound ligand |
| Tgene | >FLT3 | chr13:28713224 | chr13:28644749 | ENST00000537084 | - | 0 | 23 | 591_597 | 14 | 953 | Region | Note=Important for normal regulation of the kinase activity and for maintaining the kinase in an inactive state in the absence of bound ligand |
| Tgene | >FLT3 | chr13:28794515 | chr13:28644749 | ENST00000241453 | - | 0 | 24 | 591_597 | 14 | 994 | Region | Note=Important for normal regulation of the kinase activity and for maintaining the kinase in an inactive state in the absence of bound ligand |
| Tgene | >FLT3 | chr13:28794515 | chr13:28644749 | ENST00000537084 | - | 0 | 23 | 591_597 | 14 | 953 | Region | Note=Important for normal regulation of the kinase activity and for maintaining the kinase in an inactive state in the absence of bound ligand |
| Tgene | >FLT3 | chr13:28713224 | chr13:28644749 | ENST00000241453 | - | 0 | 24 | 27_543 | 14 | 994 | Topological domain | Extracellular |
| Tgene | >FLT3 | chr13:28713224 | chr13:28644749 | ENST00000241453 | - | 0 | 24 | 564_993 | 14 | 994 | Topological domain | Cytoplasmic |
| Tgene | >FLT3 | chr13:28713224 | chr13:28644749 | ENST00000537084 | - | 0 | 23 | 27_543 | 14 | 953 | Topological domain | Extracellular |
| Tgene | >FLT3 | chr13:28713224 | chr13:28644749 | ENST00000537084 | - | 0 | 23 | 564_993 | 14 | 953 | Topological domain | Cytoplasmic |
| Tgene | >FLT3 | chr13:28794515 | chr13:28644749 | ENST00000241453 | - | 0 | 24 | 27_543 | 14 | 994 | Topological domain | Extracellular |
| Tgene | >FLT3 | chr13:28794515 | chr13:28644749 | ENST00000241453 | - | 0 | 24 | 564_993 | 14 | 994 | Topological domain | Cytoplasmic |
| Tgene | >FLT3 | chr13:28794515 | chr13:28644749 | ENST00000537084 | - | 0 | 23 | 27_543 | 14 | 953 | Topological domain | Extracellular |
| Tgene | >FLT3 | chr13:28794515 | chr13:28644749 | ENST00000537084 | - | 0 | 23 | 564_993 | 14 | 953 | Topological domain | Cytoplasmic |
| Tgene | >FLT3 | chr13:28713224 | chr13:28644749 | ENST00000241453 | - | 0 | 24 | 544_563 | 14 | 994 | Transmembrane | Helical |
| Tgene | >FLT3 | chr13:28713224 | chr13:28644749 | ENST00000537084 | - | 0 | 23 | 544_563 | 14 | 953 | Transmembrane | Helical |
| Tgene | >FLT3 | chr13:28794515 | chr13:28644749 | ENST00000241453 | - | 0 | 24 | 544_563 | 14 | 994 | Transmembrane | Helical |
| Tgene | >FLT3 | chr13:28794515 | chr13:28644749 | ENST00000537084 | - | 0 | 23 | 544_563 | 14 | 953 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >PAN3 | chr13:28713224 | chr13:28644749 | ENST00000282391 | + | 1 | 14 | 751_789 | 0 | 576 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >PAN3 | chr13:28713224 | chr13:28644749 | ENST00000380958 | + | 1 | 19 | 751_789 | 143 | 888 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >PAN3 | chr13:28713224 | chr13:28644749 | ENST00000399613 | + | 1 | 18 | 751_789 | -3 | 688 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >PAN3 | chr13:28794515 | chr13:28644749 | ENST00000282391 | + | 1 | 14 | 751_789 | 0 | 576 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >PAN3 | chr13:28794515 | chr13:28644749 | ENST00000380958 | + | 6 | 19 | 751_789 | 333 | 888 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >PAN3 | chr13:28794515 | chr13:28644749 | ENST00000399613 | + | 5 | 18 | 751_789 | 133 | 688 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >PAN3 | chr13:28713224 | chr13:28644749 | ENST00000282391 | + | 1 | 14 | 284_299 | 0 | 576 | Motif | PABPC-interacting motif-2 (PAM-2) |
| Hgene | >PAN3 | chr13:28713224 | chr13:28644749 | ENST00000380958 | + | 1 | 19 | 284_299 | 143 | 888 | Motif | PABPC-interacting motif-2 (PAM-2) |
| Hgene | >PAN3 | chr13:28713224 | chr13:28644749 | ENST00000399613 | + | 1 | 18 | 284_299 | -3 | 688 | Motif | PABPC-interacting motif-2 (PAM-2) |
| Hgene | >PAN3 | chr13:28794515 | chr13:28644749 | ENST00000282391 | + | 1 | 14 | 284_299 | 0 | 576 | Motif | PABPC-interacting motif-2 (PAM-2) |
| Hgene | >PAN3 | chr13:28794515 | chr13:28644749 | ENST00000399613 | + | 5 | 18 | 284_299 | 133 | 688 | Motif | PABPC-interacting motif-2 (PAM-2) |
| Hgene | >PAN3 | chr13:28713224 | chr13:28644749 | ENST00000282391 | + | 1 | 14 | 570_577 | 0 | 576 | Nucleotide binding | ATP |
| Hgene | >PAN3 | chr13:28713224 | chr13:28644749 | ENST00000282391 | + | 1 | 14 | 644_645 | 0 | 576 | Nucleotide binding | ATP |
| Hgene | >PAN3 | chr13:28713224 | chr13:28644749 | ENST00000380958 | + | 1 | 19 | 570_577 | 143 | 888 | Nucleotide binding | ATP |
| Hgene | >PAN3 | chr13:28713224 | chr13:28644749 | ENST00000380958 | + | 1 | 19 | 644_645 | 143 | 888 | Nucleotide binding | ATP |
| Hgene | >PAN3 | chr13:28713224 | chr13:28644749 | ENST00000399613 | + | 1 | 18 | 570_577 | -3 | 688 | Nucleotide binding | ATP |
| Hgene | >PAN3 | chr13:28713224 | chr13:28644749 | ENST00000399613 | + | 1 | 18 | 644_645 | -3 | 688 | Nucleotide binding | ATP |
| Hgene | >PAN3 | chr13:28794515 | chr13:28644749 | ENST00000282391 | + | 1 | 14 | 570_577 | 0 | 576 | Nucleotide binding | ATP |
| Hgene | >PAN3 | chr13:28794515 | chr13:28644749 | ENST00000282391 | + | 1 | 14 | 644_645 | 0 | 576 | Nucleotide binding | ATP |
| Hgene | >PAN3 | chr13:28794515 | chr13:28644749 | ENST00000380958 | + | 6 | 19 | 570_577 | 333 | 888 | Nucleotide binding | ATP |
| Hgene | >PAN3 | chr13:28794515 | chr13:28644749 | ENST00000380958 | + | 6 | 19 | 644_645 | 333 | 888 | Nucleotide binding | ATP |
| Hgene | >PAN3 | chr13:28794515 | chr13:28644749 | ENST00000399613 | + | 5 | 18 | 570_577 | 133 | 688 | Nucleotide binding | ATP |
| Hgene | >PAN3 | chr13:28794515 | chr13:28644749 | ENST00000399613 | + | 5 | 18 | 644_645 | 133 | 688 | Nucleotide binding | ATP |
| Hgene | >PAN3 | chr13:28713224 | chr13:28644749 | ENST00000282391 | + | 1 | 14 | 463_750 | 0 | 576 | Region | Pseudokinase domain |
| Hgene | >PAN3 | chr13:28713224 | chr13:28644749 | ENST00000282391 | + | 1 | 14 | 790_887 | 0 | 576 | Region | Knob domain |
| Hgene | >PAN3 | chr13:28713224 | chr13:28644749 | ENST00000380958 | + | 1 | 19 | 463_750 | 143 | 888 | Region | Pseudokinase domain |
| Hgene | >PAN3 | chr13:28713224 | chr13:28644749 | ENST00000380958 | + | 1 | 19 | 790_887 | 143 | 888 | Region | Knob domain |
| Hgene | >PAN3 | chr13:28713224 | chr13:28644749 | ENST00000399613 | + | 1 | 18 | 463_750 | -3 | 688 | Region | Pseudokinase domain |
| Hgene | >PAN3 | chr13:28713224 | chr13:28644749 | ENST00000399613 | + | 1 | 18 | 790_887 | -3 | 688 | Region | Knob domain |
| Hgene | >PAN3 | chr13:28794515 | chr13:28644749 | ENST00000282391 | + | 1 | 14 | 463_750 | 0 | 576 | Region | Pseudokinase domain |
| Hgene | >PAN3 | chr13:28794515 | chr13:28644749 | ENST00000282391 | + | 1 | 14 | 790_887 | 0 | 576 | Region | Knob domain |
| Hgene | >PAN3 | chr13:28794515 | chr13:28644749 | ENST00000380958 | + | 6 | 19 | 463_750 | 333 | 888 | Region | Pseudokinase domain |
| Hgene | >PAN3 | chr13:28794515 | chr13:28644749 | ENST00000380958 | + | 6 | 19 | 790_887 | 333 | 888 | Region | Knob domain |
| Hgene | >PAN3 | chr13:28794515 | chr13:28644749 | ENST00000399613 | + | 5 | 18 | 463_750 | 133 | 688 | Region | Pseudokinase domain |
| Hgene | >PAN3 | chr13:28794515 | chr13:28644749 | ENST00000399613 | + | 5 | 18 | 790_887 | 133 | 688 | Region | Knob domain |
| Hgene | >PAN3 | chr13:28713224 | chr13:28644749 | ENST00000282391 | + | 1 | 14 | 43_71 | 0 | 576 | Zinc finger | C3H1-type |
| Hgene | >PAN3 | chr13:28713224 | chr13:28644749 | ENST00000399613 | + | 1 | 18 | 43_71 | -3 | 688 | Zinc finger | C3H1-type |
| Hgene | >PAN3 | chr13:28794515 | chr13:28644749 | ENST00000282391 | + | 1 | 14 | 43_71 | 0 | 576 | Zinc finger | C3H1-type |
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FusionGeneSequence for PAN3_FLT3 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_PAN3_ENST00000380958_chr13_28794515_+_FLT3_ENST00000241453_chr13_28644749_-_1313aa MNSGGGLPPPSAAASPSSSSLAAAVAVVAPPGVGGVPGGAAVGVKLKYCRYYAKDKTCFYGEECQFLHEDPAAGAAPGLGLHSNSVPLAL AGAPVAGFPPGAVAGGGAGPPPGPKKPDLGDPGTGAAAGGGGSSGGLDGPRLAIPGMDGGALTDTSLTDSYFSTSFIGVNGFGSPVETKY PLMQRMTNSSSSPSLLNDSAKPYSAHDPLTSPASSLFNDFGALNISQRRKPRKYRLGMLEERLVPMGSKARKAKNPIGCLADRCKSGVPI NMVWWNRVTENNLQTPNPTASEFIPKGGSTSRLSNVSQSNMSAFSQVFSHPSMGSPATAGLAPVVFSAMIFGTITNQDLPVIKCVLINHK NNDSSVGKSSSYPMVSESPEDLGCALRPQSSGTVYEAAAVEVDVSASITLQVLVDAPGNISCLWVFKHSSLNCQPHFDLQNRGVVSMVIL KMTETQAGEYLLFIQSEATNYTILFTVSIRNTLLYTLRRPYFRKMENQDALVCISESVPEPIVEWVLCDSQGESCKEESPAVVKKEEKVL HELFGTDIRCCARNELGRECTRLFTIDLNQTPQTTLPQLFLKVGEPLWIRCKAVHVNHGFGLTWELENKALEEGNYFEMSTYSTNRTMIR ILFAFVSSVARNDTGYYTCSSSKHPSQSALVTIVEKGFINATNSSEDYEIDQYEEFCFSVRFKAYPQIRCTWTFSRKSFPCEQKGLDNGY SISKFCNHKHQPGEYIFHAENDDAQFTKMFTLNIRRKPQVLAEASASQASCFSDGYPLPSWTWKKCSDKSPNCTEEITEGVWNRKANRKV FGQWVSSSTLNMSEAIKGFLVKCCAYNSLGTSCETILLNSPGPFPFIQDNISFYATIGVCLLFIVVLTLLICHKYKKQFRYESQLQMVQV TGSSDNEYFYVDFREYEYDLKWEFPRENLEFGKVLGSGAFGKVMNATAYGISKTGVSIQVAVKMLKEKADSSEREALMSELKMMTQLGSH ENIVNLLGACTLSGPIYLIFEYCCYGDLLNYLRSKREKFHRTWTEIFKEHNFSFYPTFQSHPNSSMPGSREVQIHPDSDQISGLHGNSFH SEDEIEYENQKRLEEEEDLNVLTFEDLLCFAYQVAKGMEFLEFKSCVHRDLAARNVLVTHGKVVKICDFGLARDIMSDSNYVVRGNARLP VKWMAPESLFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGIPVDANFYKLIQNGFKMDQPFYATEEIYIIMQSCWAFDSRKRPSFPNLTS >In-frame_PAN3_ENST00000380958_chr13_28794515_+_FLT3_ENST00000380982_chr13_28644749_-_1316aa MNSGGGLPPPSAAASPSSSSLAAAVAVVAPPGVGGVPGGAAVGVKLKYCRYYAKDKTCFYGEECQFLHEDPAAGAAPGLGLHSNSVPLAL AGAPVAGFPPGAVAGGGAGPPPGPKKPDLGDPGTGAAAGGGGSSGGLDGPRLAIPGMDGGALTDTSLTDSYFSTSFIGVNGFGSPVETKY PLMQRMTNSSSSPSLLNDSAKPYSAHDPLTSPASSLFNDFGALNISQRRKPRKYRLGMLEERLVPMGSKARKAKNPIGCLADRCKSGVPI NMVWWNRVTENNLQTPNPTASEFIPKGGSTSRLSNVSQSNMSAFSQVFSHPSMGSPATAGLAPVVFSAMIFGTITNQDLPVIKCVLINHK NNDSSVGKSSSYPMVSESPEDLGCALRPQSSGTVYEAAAVEVDVSASITLQVLVDAPGNISCLWVFKHSSLNCQPHFDLQNRGVVSMVIL KMTETQAGEYLLFIQSEATNYTILFTVSIRNTLLYTLRRPYFRKMENQDALVCISESVPEPIVEWVLCDSQGESCKEESPAVVKKEEKVL HELFGTDIRCCARNELGRECTRLFTIDLNQTPQTTLPQLFLKVGEPLWIRCKAVHVNHGFGLTWELENKALEEGNYFEMSTYSTNRTMIR ILFAFVSSVARNDTGYYTCSSSKHPSQSALVTIVEKGFINATNSSEDYEIDQYEEFCFSVRFKAYPQIRCTWTFSRKSFPCEQKGLDNGY SISKFCNHKHQPGEYIFHAENDDAQFTKMFTLNIRRKPQVLAEASASQASCFSDGYPLPSWTWKKCSDKSPNCTEEITEGVWNRKANRKV FGQWVSSSTLNMSEAIKGFLVKCCAYNSLGTSCETILLNSPGPFPFIQDNISFYATIGVCLLFIVVLTLLICHKYKKQFRYESQLQMVQV TGSSDNEYFYVDFREYEYDLKWEFPRENLEFGKVLGSGAFGKVMNATAYGISKTGVSIQVAVKMLKEKADSSEREALMSELKMMTQLGSH ENIVNLLGACTLSGPIYLIFEYCCYGDLLNYLRSKREKFHRTWTEIFKEHNFSFYPTFQSHPNSSMPGSREVQIHPDSDQISGLHGNSFH SEDEIEYENQKRLEEEEDLNVLTFEDLLCFAYQVAKGMEFLEFKSCVHRDLAARNVLVTHGKVVKICDFGLARDIMSDSNYVVRGNVRLA RLPVKWMAPESLFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGIPVDANFYKLIQNGFKMDQPFYATEEIYIIMQSCWAFDSRKRPSFPN >In-frame_PAN3_ENST00000380958_chr13_28794515_+_FLT3_ENST00000537084_chr13_28644749_-_1272aa MNSGGGLPPPSAAASPSSSSLAAAVAVVAPPGVGGVPGGAAVGVKLKYCRYYAKDKTCFYGEECQFLHEDPAAGAAPGLGLHSNSVPLAL AGAPVAGFPPGAVAGGGAGPPPGPKKPDLGDPGTGAAAGGGGSSGGLDGPRLAIPGMDGGALTDTSLTDSYFSTSFIGVNGFGSPVETKY PLMQRMTNSSSSPSLLNDSAKPYSAHDPLTSPASSLFNDFGALNISQRRKPRKYRLGMLEERLVPMGSKARKAKNPIGCLADRCKSGVPI NMVWWNRVTENNLQTPNPTASEFIPKGGSTSRLSNVSQSNMSAFSQVFSHPSMGSPATAGLAPVVFSAMIFGTITNQDLPVIKCVLINHK NNDSSVGKSSSYPMVSESPEDLGCALRPQSSGTVYEAAAVEVDVSASITLQVLVDAPGNISCLWVFKHSSLNCQPHFDLQNRGVVSMVIL KMTETQAGEYLLFIQSEATNYTILFTVSIRNTLLYTLRRPYFRKMENQDALVCISESVPEPIVEWVLCDSQGESCKEESPAVVKKEEKVL HELFGTDIRCCARNELGRECTRLFTIDLNQTPQTTLPQLFLKVGEPLWIRCKAVHVNHGFGLTWELENKALEEGNYFEMSTYSTNRTMIR ILFAFVSSVARNDTGYYTCSSSKHPSQSALVTIVEKGFINATNSSEDYEIDQYEEFCFSVRFKAYPQIRCTWTFSRKSFPCEQKGLDNGY SISKFCNHKHQPGEYIFHAENDDAQFTKMFTLNIRRKPQVLAEASASQASCFSDGYPLPSWTWKKCSDKSPNCTEEITEGVWNRKANRKV FGQWVSSSTLNMSEAIKGFLVKCCAYNSLGTSCETILLNSPGPFPFIQDNISFYATIGVCLLFIVVLTLLICHKYKKQFRYESQLQMVQV TGSSDNEYFYVDFREYEYDLKWEFPRENLEFGKVLGSGAFGKVMNATAYGISKTGVSIQVAVKMLKEKADSSEREALMSELKMMTQLGSH ENIVNLLGACTLSGPIYLIFEYCCYGDLLNYLRSKREKFHRTWTEIFKEHNFSFYPTFQSHPNSSMPGSREVQIHPDSDQISGLHGNSFH SEDEIEYENQKRLEEEEDLNVLTFEDLLCFAYQVAKGMEFLEFKSARLPVKWMAPESLFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGI PVDANFYKLIQNGFKMDQPFYATEEIYIIMQSCWAFDSRKRPSFPNLTSFLGCQLADAEEAMYQNVDGRVSECPHTYQNRRPFSREMDLG >In-frame_PAN3_ENST00000399613_chr13_28794515_+_FLT3_ENST00000241453_chr13_28644749_-_1113aa MDGGALTDTSLTDSYFSTSFIGVNGFGSPVETKYPLMQRMTNSSSSPSLLNDSAKPYSAHDPLTSPASSLFNDFGALNISQRRKTPNPTA SEFIPKGGSTSRLSNVSQSNMSAFSQVFSHPSMGSPATAGLAPVVFSAMIFGTITNQDLPVIKCVLINHKNNDSSVGKSSSYPMVSESPE DLGCALRPQSSGTVYEAAAVEVDVSASITLQVLVDAPGNISCLWVFKHSSLNCQPHFDLQNRGVVSMVILKMTETQAGEYLLFIQSEATN YTILFTVSIRNTLLYTLRRPYFRKMENQDALVCISESVPEPIVEWVLCDSQGESCKEESPAVVKKEEKVLHELFGTDIRCCARNELGREC TRLFTIDLNQTPQTTLPQLFLKVGEPLWIRCKAVHVNHGFGLTWELENKALEEGNYFEMSTYSTNRTMIRILFAFVSSVARNDTGYYTCS SSKHPSQSALVTIVEKGFINATNSSEDYEIDQYEEFCFSVRFKAYPQIRCTWTFSRKSFPCEQKGLDNGYSISKFCNHKHQPGEYIFHAE NDDAQFTKMFTLNIRRKPQVLAEASASQASCFSDGYPLPSWTWKKCSDKSPNCTEEITEGVWNRKANRKVFGQWVSSSTLNMSEAIKGFL VKCCAYNSLGTSCETILLNSPGPFPFIQDNISFYATIGVCLLFIVVLTLLICHKYKKQFRYESQLQMVQVTGSSDNEYFYVDFREYEYDL KWEFPRENLEFGKVLGSGAFGKVMNATAYGISKTGVSIQVAVKMLKEKADSSEREALMSELKMMTQLGSHENIVNLLGACTLSGPIYLIF EYCCYGDLLNYLRSKREKFHRTWTEIFKEHNFSFYPTFQSHPNSSMPGSREVQIHPDSDQISGLHGNSFHSEDEIEYENQKRLEEEEDLN VLTFEDLLCFAYQVAKGMEFLEFKSCVHRDLAARNVLVTHGKVVKICDFGLARDIMSDSNYVVRGNARLPVKWMAPESLFEGIYTIKSDV WSYGILLWEIFSLGVNPYPGIPVDANFYKLIQNGFKMDQPFYATEEIYIIMQSCWAFDSRKRPSFPNLTSFLGCQLADAEEAMYQNVDGR >In-frame_PAN3_ENST00000399613_chr13_28794515_+_FLT3_ENST00000380982_chr13_28644749_-_1116aa MDGGALTDTSLTDSYFSTSFIGVNGFGSPVETKYPLMQRMTNSSSSPSLLNDSAKPYSAHDPLTSPASSLFNDFGALNISQRRKTPNPTA SEFIPKGGSTSRLSNVSQSNMSAFSQVFSHPSMGSPATAGLAPVVFSAMIFGTITNQDLPVIKCVLINHKNNDSSVGKSSSYPMVSESPE DLGCALRPQSSGTVYEAAAVEVDVSASITLQVLVDAPGNISCLWVFKHSSLNCQPHFDLQNRGVVSMVILKMTETQAGEYLLFIQSEATN YTILFTVSIRNTLLYTLRRPYFRKMENQDALVCISESVPEPIVEWVLCDSQGESCKEESPAVVKKEEKVLHELFGTDIRCCARNELGREC TRLFTIDLNQTPQTTLPQLFLKVGEPLWIRCKAVHVNHGFGLTWELENKALEEGNYFEMSTYSTNRTMIRILFAFVSSVARNDTGYYTCS SSKHPSQSALVTIVEKGFINATNSSEDYEIDQYEEFCFSVRFKAYPQIRCTWTFSRKSFPCEQKGLDNGYSISKFCNHKHQPGEYIFHAE NDDAQFTKMFTLNIRRKPQVLAEASASQASCFSDGYPLPSWTWKKCSDKSPNCTEEITEGVWNRKANRKVFGQWVSSSTLNMSEAIKGFL VKCCAYNSLGTSCETILLNSPGPFPFIQDNISFYATIGVCLLFIVVLTLLICHKYKKQFRYESQLQMVQVTGSSDNEYFYVDFREYEYDL KWEFPRENLEFGKVLGSGAFGKVMNATAYGISKTGVSIQVAVKMLKEKADSSEREALMSELKMMTQLGSHENIVNLLGACTLSGPIYLIF EYCCYGDLLNYLRSKREKFHRTWTEIFKEHNFSFYPTFQSHPNSSMPGSREVQIHPDSDQISGLHGNSFHSEDEIEYENQKRLEEEEDLN VLTFEDLLCFAYQVAKGMEFLEFKSCVHRDLAARNVLVTHGKVVKICDFGLARDIMSDSNYVVRGNVRLARLPVKWMAPESLFEGIYTIK SDVWSYGILLWEIFSLGVNPYPGIPVDANFYKLIQNGFKMDQPFYATEEIYIIMQSCWAFDSRKRPSFPNLTSFLGCQLADAEEAMYQNV >In-frame_PAN3_ENST00000399613_chr13_28794515_+_FLT3_ENST00000537084_chr13_28644749_-_1072aa MDGGALTDTSLTDSYFSTSFIGVNGFGSPVETKYPLMQRMTNSSSSPSLLNDSAKPYSAHDPLTSPASSLFNDFGALNISQRRKTPNPTA SEFIPKGGSTSRLSNVSQSNMSAFSQVFSHPSMGSPATAGLAPVVFSAMIFGTITNQDLPVIKCVLINHKNNDSSVGKSSSYPMVSESPE DLGCALRPQSSGTVYEAAAVEVDVSASITLQVLVDAPGNISCLWVFKHSSLNCQPHFDLQNRGVVSMVILKMTETQAGEYLLFIQSEATN YTILFTVSIRNTLLYTLRRPYFRKMENQDALVCISESVPEPIVEWVLCDSQGESCKEESPAVVKKEEKVLHELFGTDIRCCARNELGREC TRLFTIDLNQTPQTTLPQLFLKVGEPLWIRCKAVHVNHGFGLTWELENKALEEGNYFEMSTYSTNRTMIRILFAFVSSVARNDTGYYTCS SSKHPSQSALVTIVEKGFINATNSSEDYEIDQYEEFCFSVRFKAYPQIRCTWTFSRKSFPCEQKGLDNGYSISKFCNHKHQPGEYIFHAE NDDAQFTKMFTLNIRRKPQVLAEASASQASCFSDGYPLPSWTWKKCSDKSPNCTEEITEGVWNRKANRKVFGQWVSSSTLNMSEAIKGFL VKCCAYNSLGTSCETILLNSPGPFPFIQDNISFYATIGVCLLFIVVLTLLICHKYKKQFRYESQLQMVQVTGSSDNEYFYVDFREYEYDL KWEFPRENLEFGKVLGSGAFGKVMNATAYGISKTGVSIQVAVKMLKEKADSSEREALMSELKMMTQLGSHENIVNLLGACTLSGPIYLIF EYCCYGDLLNYLRSKREKFHRTWTEIFKEHNFSFYPTFQSHPNSSMPGSREVQIHPDSDQISGLHGNSFHSEDEIEYENQKRLEEEEDLN VLTFEDLLCFAYQVAKGMEFLEFKSARLPVKWMAPESLFEGIYTIKSDVWSYGILLWEIFSLGVNPYPGIPVDANFYKLIQNGFKMDQPF |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_PAN3_ENST00000380958_chr13_28794515_+_FLT3_ENST00000241453_chr13_28644749_-_3939nt ATGAACAGTGGCGGCGGCCTCCCGCCCCCCTCGGCCGCCGCCTCCCCTTCCTCCTCCTCGCTGGCGGCGGCGGTGGCGGTGGTGGCCCCG CCGGGGGTCGGGGGTGTCCCCGGCGGGGCGGCGGTAGGAGTGAAGCTGAAGTACTGCCGCTACTACGCTAAGGATAAGACTTGCTTCTAC GGGGAGGAGTGTCAGTTCCTGCATGAGGACCCTGCCGCCGGGGCTGCCCCGGGCCTCGGCCTCCATAGCAACAGCGTCCCCCTGGCTCTG GCTGGTGCACCCGTGGCCGGCTTTCCGCCGGGAGCCGTCGCGGGCGGGGGAGCTGGGCCGCCCCCCGGGCCCAAGAAGCCGGACCTGGGG GACCCGGGGACCGGAGCCGCAGCCGGCGGAGGAGGCAGTAGCGGGGGACTCGATGGACCGCGGCTGGCAATTCCAGGAATGGATGGAGGT GCTTTAACTGATACAAGTCTCACAGATTCCTATTTTAGCACCAGCTTTATTGGAGTCAATGGATTTGGAAGCCCTGTAGAAACAAAATAT CCCCTGATGCAGAGAATGACTAATAGTAGCAGCTCCCCAAGCCTTCTAAATGACAGTGCCAAGCCATATTCAGCCCATGATCCTCTAACA TCACCTGCTTCATCCTTGTTTAATGACTTTGGTGCCCTCAACATCTCTCAGAGACGAAAGCCAAGGAAGTATCGCCTGGGGATGCTGGAG GAGAGGCTAGTTCCGATGGGATCAAAGGCACGAAAAGCAAAGAACCCTATTGGCTGCCTTGCTGACAGGTGTAAATCAGGAGTACCCATC AATATGGTTTGGTGGAACAGAGTCACAGAAAACAATTTACAGACACCAAATCCTACTGCAAGCGAGTTTATTCCTAAAGGAGGATCAACC TCCAGGCTGAGTAACGTGTCCCAGTCAAATATGTCTGCCTTCTCTCAAGTTTTCTCTCACCCATCCATGGGAAGCCCTGCTACTGCTGGA TTAGCGCCAGTTGTTTTTTCTGCAATGATATTTGGGACTATTACAAATCAAGATCTGCCTGTGATCAAGTGTGTTTTAATCAATCATAAG AACAATGATTCATCAGTGGGGAAGTCATCATCATATCCCATGGTATCAGAATCCCCGGAAGACCTCGGGTGTGCGTTGAGACCCCAGAGC TCAGGGACAGTGTACGAAGCTGCCGCTGTGGAAGTGGATGTATCTGCTTCCATCACACTGCAAGTGCTGGTCGACGCCCCAGGGAACATT TCCTGTCTCTGGGTCTTTAAGCACAGCTCCCTGAATTGCCAGCCACATTTTGATTTACAAAACAGAGGAGTTGTTTCCATGGTCATTTTG AAAATGACAGAAACCCAAGCTGGAGAATACCTACTTTTTATTCAGAGTGAAGCTACCAATTACACAATATTGTTTACAGTGAGTATAAGA AATACCCTGCTTTACACATTAAGAAGACCTTACTTTAGAAAAATGGAAAACCAGGACGCCCTGGTCTGCATATCTGAGAGCGTTCCAGAG CCGATCGTGGAATGGGTGCTTTGCGATTCACAGGGGGAAAGCTGTAAAGAAGAAAGTCCAGCTGTTGTTAAAAAGGAGGAAAAAGTGCTT CATGAATTATTTGGGACGGACATAAGGTGCTGTGCCAGAAATGAACTGGGCAGGGAATGCACCAGGCTGTTCACAATAGATCTAAATCAA ACTCCTCAGACCACATTGCCACAATTATTTCTTAAAGTAGGGGAACCCTTATGGATAAGGTGCAAAGCTGTTCATGTGAACCATGGATTC GGGCTCACCTGGGAATTAGAAAACAAAGCACTCGAGGAGGGCAACTACTTTGAGATGAGTACCTATTCAACAAACAGAACTATGATACGG ATTCTGTTTGCTTTTGTATCATCAGTGGCAAGAAACGACACCGGATACTACACTTGTTCCTCTTCAAAGCATCCCAGTCAATCAGCTTTG GTTACCATCGTAGAAAAGGGATTTATAAATGCTACCAATTCAAGTGAAGATTATGAAATTGACCAATATGAAGAGTTTTGTTTTTCTGTC AGGTTTAAAGCCTACCCACAAATCAGATGTACGTGGACCTTCTCTCGAAAATCATTTCCTTGTGAGCAAAAGGGTCTTGATAACGGATAC AGCATATCCAAGTTTTGCAATCATAAGCACCAGCCAGGAGAATATATATTCCATGCAGAAAATGATGATGCCCAATTTACCAAAATGTTC ACGCTGAATATAAGAAGGAAACCTCAAGTGCTCGCAGAAGCATCGGCAAGTCAGGCGTCCTGTTTCTCGGATGGATACCCATTACCATCT TGGACCTGGAAGAAGTGTTCAGACAAGTCTCCCAACTGCACAGAAGAGATCACAGAAGGAGTCTGGAATAGAAAGGCTAACAGAAAAGTG TTTGGACAGTGGGTGTCGAGCAGTACTCTAAACATGAGTGAAGCCATAAAAGGGTTCCTGGTCAAGTGCTGTGCATACAATTCCCTTGGC ACATCTTGTGAGACGATCCTTTTAAACTCTCCAGGCCCCTTCCCTTTCATCCAAGACAACATCTCATTCTATGCAACAATTGGTGTTTGT CTCCTCTTCATTGTCGTTTTAACCCTGCTAATTTGTCACAAGTACAAAAAGCAATTTAGGTATGAAAGCCAGCTACAGATGGTACAGGTG ACCGGCTCCTCAGATAATGAGTACTTCTACGTTGATTTCAGAGAATATGAATATGATCTCAAATGGGAGTTTCCAAGAGAAAATTTAGAG TTTGGGAAGGTACTAGGATCAGGTGCTTTTGGAAAAGTGATGAACGCAACAGCTTATGGAATTAGCAAAACAGGAGTCTCAATCCAGGTT GCCGTCAAAATGCTGAAAGAAAAAGCAGACAGCTCTGAAAGAGAGGCACTCATGTCAGAACTCAAGATGATGACCCAGCTGGGAAGCCAC GAGAATATTGTGAACCTGCTGGGGGCGTGCACACTGTCAGGACCAATTTACTTGATTTTTGAATACTGTTGCTATGGTGATCTTCTCAAC TATCTAAGAAGTAAAAGAGAAAAATTTCACAGGACTTGGACAGAGATTTTCAAGGAACACAATTTCAGTTTTTACCCCACTTTCCAATCA CATCCAAATTCCAGCATGCCTGGTTCAAGAGAAGTTCAGATACACCCGGACTCGGATCAAATCTCAGGGCTTCATGGGAATTCATTTCAC TCTGAAGATGAAATTGAATATGAAAACCAAAAAAGGCTGGAAGAAGAGGAGGACTTGAATGTGCTTACATTTGAAGATCTTCTTTGCTTT GCATATCAAGTTGCCAAAGGAATGGAATTTCTGGAATTTAAGTCGTGTGTTCACAGAGACCTGGCCGCCAGGAACGTGCTTGTCACCCAC GGGAAAGTGGTGAAGATATGTGACTTTGGATTGGCTCGAGATATCATGAGTGATTCCAACTATGTTGTCAGGGGCAATGCCCGTCTGCCT GTAAAATGGATGGCCCCCGAAAGCCTGTTTGAAGGCATCTACACCATTAAGAGTGATGTCTGGTCATATGGAATATTACTGTGGGAAATC TTCTCACTTGGTGTGAATCCTTACCCTGGCATTCCGGTTGATGCTAACTTCTACAAACTGATTCAAAATGGATTTAAAATGGATCAGCCA TTTTATGCTACAGAAGAAATATACATTATAATGCAATCCTGCTGGGCTTTTGACTCAAGGAAACGGCCATCCTTCCCTAATTTGACTTCG TTTTTAGGATGTCAGCTGGCAGATGCAGAAGAAGCGATGTATCAGAATGTGGATGGCCGTGTTTCGGAATGTCCTCACACCTACCAAAAC >In-frame_PAN3_ENST00000380958_chr13_28794515_+_FLT3_ENST00000380982_chr13_28644749_-_3948nt ATGAACAGTGGCGGCGGCCTCCCGCCCCCCTCGGCCGCCGCCTCCCCTTCCTCCTCCTCGCTGGCGGCGGCGGTGGCGGTGGTGGCCCCG CCGGGGGTCGGGGGTGTCCCCGGCGGGGCGGCGGTAGGAGTGAAGCTGAAGTACTGCCGCTACTACGCTAAGGATAAGACTTGCTTCTAC GGGGAGGAGTGTCAGTTCCTGCATGAGGACCCTGCCGCCGGGGCTGCCCCGGGCCTCGGCCTCCATAGCAACAGCGTCCCCCTGGCTCTG GCTGGTGCACCCGTGGCCGGCTTTCCGCCGGGAGCCGTCGCGGGCGGGGGAGCTGGGCCGCCCCCCGGGCCCAAGAAGCCGGACCTGGGG GACCCGGGGACCGGAGCCGCAGCCGGCGGAGGAGGCAGTAGCGGGGGACTCGATGGACCGCGGCTGGCAATTCCAGGAATGGATGGAGGT GCTTTAACTGATACAAGTCTCACAGATTCCTATTTTAGCACCAGCTTTATTGGAGTCAATGGATTTGGAAGCCCTGTAGAAACAAAATAT CCCCTGATGCAGAGAATGACTAATAGTAGCAGCTCCCCAAGCCTTCTAAATGACAGTGCCAAGCCATATTCAGCCCATGATCCTCTAACA TCACCTGCTTCATCCTTGTTTAATGACTTTGGTGCCCTCAACATCTCTCAGAGACGAAAGCCAAGGAAGTATCGCCTGGGGATGCTGGAG GAGAGGCTAGTTCCGATGGGATCAAAGGCACGAAAAGCAAAGAACCCTATTGGCTGCCTTGCTGACAGGTGTAAATCAGGAGTACCCATC AATATGGTTTGGTGGAACAGAGTCACAGAAAACAATTTACAGACACCAAATCCTACTGCAAGCGAGTTTATTCCTAAAGGAGGATCAACC TCCAGGCTGAGTAACGTGTCCCAGTCAAATATGTCTGCCTTCTCTCAAGTTTTCTCTCACCCATCCATGGGAAGCCCTGCTACTGCTGGA TTAGCGCCAGTTGTTTTTTCTGCAATGATATTTGGGACTATTACAAATCAAGATCTGCCTGTGATCAAGTGTGTTTTAATCAATCATAAG AACAATGATTCATCAGTGGGGAAGTCATCATCATATCCCATGGTATCAGAATCCCCGGAAGACCTCGGGTGTGCGTTGAGACCCCAGAGC TCAGGGACAGTGTACGAAGCTGCCGCTGTGGAAGTGGATGTATCTGCTTCCATCACACTGCAAGTGCTGGTCGACGCCCCAGGGAACATT TCCTGTCTCTGGGTCTTTAAGCACAGCTCCCTGAATTGCCAGCCACATTTTGATTTACAAAACAGAGGAGTTGTTTCCATGGTCATTTTG AAAATGACAGAAACCCAAGCTGGAGAATACCTACTTTTTATTCAGAGTGAAGCTACCAATTACACAATATTGTTTACAGTGAGTATAAGA AATACCCTGCTTTACACATTAAGAAGACCTTACTTTAGAAAAATGGAAAACCAGGACGCCCTGGTCTGCATATCTGAGAGCGTTCCAGAG CCGATCGTGGAATGGGTGCTTTGCGATTCACAGGGGGAAAGCTGTAAAGAAGAAAGTCCAGCTGTTGTTAAAAAGGAGGAAAAAGTGCTT CATGAATTATTTGGGACGGACATAAGGTGCTGTGCCAGAAATGAACTGGGCAGGGAATGCACCAGGCTGTTCACAATAGATCTAAATCAA ACTCCTCAGACCACATTGCCACAATTATTTCTTAAAGTAGGGGAACCCTTATGGATAAGGTGCAAAGCTGTTCATGTGAACCATGGATTC GGGCTCACCTGGGAATTAGAAAACAAAGCACTCGAGGAGGGCAACTACTTTGAGATGAGTACCTATTCAACAAACAGAACTATGATACGG ATTCTGTTTGCTTTTGTATCATCAGTGGCAAGAAACGACACCGGATACTACACTTGTTCCTCTTCAAAGCATCCCAGTCAATCAGCTTTG GTTACCATCGTAGAAAAGGGATTTATAAATGCTACCAATTCAAGTGAAGATTATGAAATTGACCAATATGAAGAGTTTTGTTTTTCTGTC AGGTTTAAAGCCTACCCACAAATCAGATGTACGTGGACCTTCTCTCGAAAATCATTTCCTTGTGAGCAAAAGGGTCTTGATAACGGATAC AGCATATCCAAGTTTTGCAATCATAAGCACCAGCCAGGAGAATATATATTCCATGCAGAAAATGATGATGCCCAATTTACCAAAATGTTC ACGCTGAATATAAGAAGGAAACCTCAAGTGCTCGCAGAAGCATCGGCAAGTCAGGCGTCCTGTTTCTCGGATGGATACCCATTACCATCT TGGACCTGGAAGAAGTGTTCAGACAAGTCTCCCAACTGCACAGAAGAGATCACAGAAGGAGTCTGGAATAGAAAGGCTAACAGAAAAGTG TTTGGACAGTGGGTGTCGAGCAGTACTCTAAACATGAGTGAAGCCATAAAAGGGTTCCTGGTCAAGTGCTGTGCATACAATTCCCTTGGC ACATCTTGTGAGACGATCCTTTTAAACTCTCCAGGCCCCTTCCCTTTCATCCAAGACAACATCTCATTCTATGCAACAATTGGTGTTTGT CTCCTCTTCATTGTCGTTTTAACCCTGCTAATTTGTCACAAGTACAAAAAGCAATTTAGGTATGAAAGCCAGCTACAGATGGTACAGGTG ACCGGCTCCTCAGATAATGAGTACTTCTACGTTGATTTCAGAGAATATGAATATGATCTCAAATGGGAGTTTCCAAGAGAAAATTTAGAG TTTGGGAAGGTACTAGGATCAGGTGCTTTTGGAAAAGTGATGAACGCAACAGCTTATGGAATTAGCAAAACAGGAGTCTCAATCCAGGTT GCCGTCAAAATGCTGAAAGAAAAAGCAGACAGCTCTGAAAGAGAGGCACTCATGTCAGAACTCAAGATGATGACCCAGCTGGGAAGCCAC GAGAATATTGTGAACCTGCTGGGGGCGTGCACACTGTCAGGACCAATTTACTTGATTTTTGAATACTGTTGCTATGGTGATCTTCTCAAC TATCTAAGAAGTAAAAGAGAAAAATTTCACAGGACTTGGACAGAGATTTTCAAGGAACACAATTTCAGTTTTTACCCCACTTTCCAATCA CATCCAAATTCCAGCATGCCTGGTTCAAGAGAAGTTCAGATACACCCGGACTCGGATCAAATCTCAGGGCTTCATGGGAATTCATTTCAC TCTGAAGATGAAATTGAATATGAAAACCAAAAAAGGCTGGAAGAAGAGGAGGACTTGAATGTGCTTACATTTGAAGATCTTCTTTGCTTT GCATATCAAGTTGCCAAAGGAATGGAATTTCTGGAATTTAAGTCGTGTGTTCACAGAGACCTGGCCGCCAGGAACGTGCTTGTCACCCAC GGGAAAGTGGTGAAGATATGTGACTTTGGATTGGCTCGAGATATCATGAGTGATTCCAACTATGTTGTCAGGGGCAATGTGAGGCTGGCC CGTCTGCCTGTAAAATGGATGGCCCCCGAAAGCCTGTTTGAAGGCATCTACACCATTAAGAGTGATGTCTGGTCATATGGAATATTACTG TGGGAAATCTTCTCACTTGGTGTGAATCCTTACCCTGGCATTCCGGTTGATGCTAACTTCTACAAACTGATTCAAAATGGATTTAAAATG GATCAGCCATTTTATGCTACAGAAGAAATATACATTATAATGCAATCCTGCTGGGCTTTTGACTCAAGGAAACGGCCATCCTTCCCTAAT TTGACTTCGTTTTTAGGATGTCAGCTGGCAGATGCAGAAGAAGCGATGTATCAGAATGTGGATGGCCGTGTTTCGGAATGTCCTCACACC >In-frame_PAN3_ENST00000380958_chr13_28794515_+_FLT3_ENST00000537084_chr13_28644749_-_3816nt ATGAACAGTGGCGGCGGCCTCCCGCCCCCCTCGGCCGCCGCCTCCCCTTCCTCCTCCTCGCTGGCGGCGGCGGTGGCGGTGGTGGCCCCG CCGGGGGTCGGGGGTGTCCCCGGCGGGGCGGCGGTAGGAGTGAAGCTGAAGTACTGCCGCTACTACGCTAAGGATAAGACTTGCTTCTAC GGGGAGGAGTGTCAGTTCCTGCATGAGGACCCTGCCGCCGGGGCTGCCCCGGGCCTCGGCCTCCATAGCAACAGCGTCCCCCTGGCTCTG GCTGGTGCACCCGTGGCCGGCTTTCCGCCGGGAGCCGTCGCGGGCGGGGGAGCTGGGCCGCCCCCCGGGCCCAAGAAGCCGGACCTGGGG GACCCGGGGACCGGAGCCGCAGCCGGCGGAGGAGGCAGTAGCGGGGGACTCGATGGACCGCGGCTGGCAATTCCAGGAATGGATGGAGGT GCTTTAACTGATACAAGTCTCACAGATTCCTATTTTAGCACCAGCTTTATTGGAGTCAATGGATTTGGAAGCCCTGTAGAAACAAAATAT CCCCTGATGCAGAGAATGACTAATAGTAGCAGCTCCCCAAGCCTTCTAAATGACAGTGCCAAGCCATATTCAGCCCATGATCCTCTAACA TCACCTGCTTCATCCTTGTTTAATGACTTTGGTGCCCTCAACATCTCTCAGAGACGAAAGCCAAGGAAGTATCGCCTGGGGATGCTGGAG GAGAGGCTAGTTCCGATGGGATCAAAGGCACGAAAAGCAAAGAACCCTATTGGCTGCCTTGCTGACAGGTGTAAATCAGGAGTACCCATC AATATGGTTTGGTGGAACAGAGTCACAGAAAACAATTTACAGACACCAAATCCTACTGCAAGCGAGTTTATTCCTAAAGGAGGATCAACC TCCAGGCTGAGTAACGTGTCCCAGTCAAATATGTCTGCCTTCTCTCAAGTTTTCTCTCACCCATCCATGGGAAGCCCTGCTACTGCTGGA TTAGCGCCAGTTGTTTTTTCTGCAATGATATTTGGGACTATTACAAATCAAGATCTGCCTGTGATCAAGTGTGTTTTAATCAATCATAAG AACAATGATTCATCAGTGGGGAAGTCATCATCATATCCCATGGTATCAGAATCCCCGGAAGACCTCGGGTGTGCGTTGAGACCCCAGAGC TCAGGGACAGTGTACGAAGCTGCCGCTGTGGAAGTGGATGTATCTGCTTCCATCACACTGCAAGTGCTGGTCGACGCCCCAGGGAACATT TCCTGTCTCTGGGTCTTTAAGCACAGCTCCCTGAATTGCCAGCCACATTTTGATTTACAAAACAGAGGAGTTGTTTCCATGGTCATTTTG AAAATGACAGAAACCCAAGCTGGAGAATACCTACTTTTTATTCAGAGTGAAGCTACCAATTACACAATATTGTTTACAGTGAGTATAAGA AATACCCTGCTTTACACATTAAGAAGACCTTACTTTAGAAAAATGGAAAACCAGGACGCCCTGGTCTGCATATCTGAGAGCGTTCCAGAG CCGATCGTGGAATGGGTGCTTTGCGATTCACAGGGGGAAAGCTGTAAAGAAGAAAGTCCAGCTGTTGTTAAAAAGGAGGAAAAAGTGCTT CATGAATTATTTGGGACGGACATAAGGTGCTGTGCCAGAAATGAACTGGGCAGGGAATGCACCAGGCTGTTCACAATAGATCTAAATCAA ACTCCTCAGACCACATTGCCACAATTATTTCTTAAAGTAGGGGAACCCTTATGGATAAGGTGCAAAGCTGTTCATGTGAACCATGGATTC GGGCTCACCTGGGAATTAGAAAACAAAGCACTCGAGGAGGGCAACTACTTTGAGATGAGTACCTATTCAACAAACAGAACTATGATACGG ATTCTGTTTGCTTTTGTATCATCAGTGGCAAGAAACGACACCGGATACTACACTTGTTCCTCTTCAAAGCATCCCAGTCAATCAGCTTTG GTTACCATCGTAGAAAAGGGATTTATAAATGCTACCAATTCAAGTGAAGATTATGAAATTGACCAATATGAAGAGTTTTGTTTTTCTGTC AGGTTTAAAGCCTACCCACAAATCAGATGTACGTGGACCTTCTCTCGAAAATCATTTCCTTGTGAGCAAAAGGGTCTTGATAACGGATAC AGCATATCCAAGTTTTGCAATCATAAGCACCAGCCAGGAGAATATATATTCCATGCAGAAAATGATGATGCCCAATTTACCAAAATGTTC ACGCTGAATATAAGAAGGAAACCTCAAGTGCTCGCAGAAGCATCGGCAAGTCAGGCGTCCTGTTTCTCGGATGGATACCCATTACCATCT TGGACCTGGAAGAAGTGTTCAGACAAGTCTCCCAACTGCACAGAAGAGATCACAGAAGGAGTCTGGAATAGAAAGGCTAACAGAAAAGTG TTTGGACAGTGGGTGTCGAGCAGTACTCTAAACATGAGTGAAGCCATAAAAGGGTTCCTGGTCAAGTGCTGTGCATACAATTCCCTTGGC ACATCTTGTGAGACGATCCTTTTAAACTCTCCAGGCCCCTTCCCTTTCATCCAAGACAACATCTCATTCTATGCAACAATTGGTGTTTGT CTCCTCTTCATTGTCGTTTTAACCCTGCTAATTTGTCACAAGTACAAAAAGCAATTTAGGTATGAAAGCCAGCTACAGATGGTACAGGTG ACCGGCTCCTCAGATAATGAGTACTTCTACGTTGATTTCAGAGAATATGAATATGATCTCAAATGGGAGTTTCCAAGAGAAAATTTAGAG TTTGGGAAGGTACTAGGATCAGGTGCTTTTGGAAAAGTGATGAACGCAACAGCTTATGGAATTAGCAAAACAGGAGTCTCAATCCAGGTT GCCGTCAAAATGCTGAAAGAAAAAGCAGACAGCTCTGAAAGAGAGGCACTCATGTCAGAACTCAAGATGATGACCCAGCTGGGAAGCCAC GAGAATATTGTGAACCTGCTGGGGGCGTGCACACTGTCAGGACCAATTTACTTGATTTTTGAATACTGTTGCTATGGTGATCTTCTCAAC TATCTAAGAAGTAAAAGAGAAAAATTTCACAGGACTTGGACAGAGATTTTCAAGGAACACAATTTCAGTTTTTACCCCACTTTCCAATCA CATCCAAATTCCAGCATGCCTGGTTCAAGAGAAGTTCAGATACACCCGGACTCGGATCAAATCTCAGGGCTTCATGGGAATTCATTTCAC TCTGAAGATGAAATTGAATATGAAAACCAAAAAAGGCTGGAAGAAGAGGAGGACTTGAATGTGCTTACATTTGAAGATCTTCTTTGCTTT GCATATCAAGTTGCCAAAGGAATGGAATTTCTGGAATTTAAGTCGGCCCGTCTGCCTGTAAAATGGATGGCCCCCGAAAGCCTGTTTGAA GGCATCTACACCATTAAGAGTGATGTCTGGTCATATGGAATATTACTGTGGGAAATCTTCTCACTTGGTGTGAATCCTTACCCTGGCATT CCGGTTGATGCTAACTTCTACAAACTGATTCAAAATGGATTTAAAATGGATCAGCCATTTTATGCTACAGAAGAAATATACATTATAATG CAATCCTGCTGGGCTTTTGACTCAAGGAAACGGCCATCCTTCCCTAATTTGACTTCGTTTTTAGGATGTCAGCTGGCAGATGCAGAAGAA GCGATGTATCAGAATGTGGATGGCCGTGTTTCGGAATGTCCTCACACCTACCAAAACAGGCGACCTTTCAGCAGAGAGATGGATTTGGGG >In-frame_PAN3_ENST00000399613_chr13_28794515_+_FLT3_ENST00000241453_chr13_28644749_-_3339nt ATGGATGGAGGTGCTTTAACTGATACAAGTCTCACAGATTCCTATTTTAGCACCAGCTTTATTGGAGTCAATGGATTTGGAAGCCCTGTA GAAACAAAATATCCCCTGATGCAGAGAATGACTAATAGTAGCAGCTCCCCAAGCCTTCTAAATGACAGTGCCAAGCCATATTCAGCCCAT GATCCTCTAACATCACCTGCTTCATCCTTGTTTAATGACTTTGGTGCCCTCAACATCTCTCAGAGACGAAAGACACCAAATCCTACTGCA AGCGAGTTTATTCCTAAAGGAGGATCAACCTCCAGGCTGAGTAACGTGTCCCAGTCAAATATGTCTGCCTTCTCTCAAGTTTTCTCTCAC CCATCCATGGGAAGCCCTGCTACTGCTGGATTAGCGCCAGTTGTTTTTTCTGCAATGATATTTGGGACTATTACAAATCAAGATCTGCCT GTGATCAAGTGTGTTTTAATCAATCATAAGAACAATGATTCATCAGTGGGGAAGTCATCATCATATCCCATGGTATCAGAATCCCCGGAA GACCTCGGGTGTGCGTTGAGACCCCAGAGCTCAGGGACAGTGTACGAAGCTGCCGCTGTGGAAGTGGATGTATCTGCTTCCATCACACTG CAAGTGCTGGTCGACGCCCCAGGGAACATTTCCTGTCTCTGGGTCTTTAAGCACAGCTCCCTGAATTGCCAGCCACATTTTGATTTACAA AACAGAGGAGTTGTTTCCATGGTCATTTTGAAAATGACAGAAACCCAAGCTGGAGAATACCTACTTTTTATTCAGAGTGAAGCTACCAAT TACACAATATTGTTTACAGTGAGTATAAGAAATACCCTGCTTTACACATTAAGAAGACCTTACTTTAGAAAAATGGAAAACCAGGACGCC CTGGTCTGCATATCTGAGAGCGTTCCAGAGCCGATCGTGGAATGGGTGCTTTGCGATTCACAGGGGGAAAGCTGTAAAGAAGAAAGTCCA GCTGTTGTTAAAAAGGAGGAAAAAGTGCTTCATGAATTATTTGGGACGGACATAAGGTGCTGTGCCAGAAATGAACTGGGCAGGGAATGC ACCAGGCTGTTCACAATAGATCTAAATCAAACTCCTCAGACCACATTGCCACAATTATTTCTTAAAGTAGGGGAACCCTTATGGATAAGG TGCAAAGCTGTTCATGTGAACCATGGATTCGGGCTCACCTGGGAATTAGAAAACAAAGCACTCGAGGAGGGCAACTACTTTGAGATGAGT ACCTATTCAACAAACAGAACTATGATACGGATTCTGTTTGCTTTTGTATCATCAGTGGCAAGAAACGACACCGGATACTACACTTGTTCC TCTTCAAAGCATCCCAGTCAATCAGCTTTGGTTACCATCGTAGAAAAGGGATTTATAAATGCTACCAATTCAAGTGAAGATTATGAAATT GACCAATATGAAGAGTTTTGTTTTTCTGTCAGGTTTAAAGCCTACCCACAAATCAGATGTACGTGGACCTTCTCTCGAAAATCATTTCCT TGTGAGCAAAAGGGTCTTGATAACGGATACAGCATATCCAAGTTTTGCAATCATAAGCACCAGCCAGGAGAATATATATTCCATGCAGAA AATGATGATGCCCAATTTACCAAAATGTTCACGCTGAATATAAGAAGGAAACCTCAAGTGCTCGCAGAAGCATCGGCAAGTCAGGCGTCC TGTTTCTCGGATGGATACCCATTACCATCTTGGACCTGGAAGAAGTGTTCAGACAAGTCTCCCAACTGCACAGAAGAGATCACAGAAGGA GTCTGGAATAGAAAGGCTAACAGAAAAGTGTTTGGACAGTGGGTGTCGAGCAGTACTCTAAACATGAGTGAAGCCATAAAAGGGTTCCTG GTCAAGTGCTGTGCATACAATTCCCTTGGCACATCTTGTGAGACGATCCTTTTAAACTCTCCAGGCCCCTTCCCTTTCATCCAAGACAAC ATCTCATTCTATGCAACAATTGGTGTTTGTCTCCTCTTCATTGTCGTTTTAACCCTGCTAATTTGTCACAAGTACAAAAAGCAATTTAGG TATGAAAGCCAGCTACAGATGGTACAGGTGACCGGCTCCTCAGATAATGAGTACTTCTACGTTGATTTCAGAGAATATGAATATGATCTC AAATGGGAGTTTCCAAGAGAAAATTTAGAGTTTGGGAAGGTACTAGGATCAGGTGCTTTTGGAAAAGTGATGAACGCAACAGCTTATGGA ATTAGCAAAACAGGAGTCTCAATCCAGGTTGCCGTCAAAATGCTGAAAGAAAAAGCAGACAGCTCTGAAAGAGAGGCACTCATGTCAGAA CTCAAGATGATGACCCAGCTGGGAAGCCACGAGAATATTGTGAACCTGCTGGGGGCGTGCACACTGTCAGGACCAATTTACTTGATTTTT GAATACTGTTGCTATGGTGATCTTCTCAACTATCTAAGAAGTAAAAGAGAAAAATTTCACAGGACTTGGACAGAGATTTTCAAGGAACAC AATTTCAGTTTTTACCCCACTTTCCAATCACATCCAAATTCCAGCATGCCTGGTTCAAGAGAAGTTCAGATACACCCGGACTCGGATCAA ATCTCAGGGCTTCATGGGAATTCATTTCACTCTGAAGATGAAATTGAATATGAAAACCAAAAAAGGCTGGAAGAAGAGGAGGACTTGAAT GTGCTTACATTTGAAGATCTTCTTTGCTTTGCATATCAAGTTGCCAAAGGAATGGAATTTCTGGAATTTAAGTCGTGTGTTCACAGAGAC CTGGCCGCCAGGAACGTGCTTGTCACCCACGGGAAAGTGGTGAAGATATGTGACTTTGGATTGGCTCGAGATATCATGAGTGATTCCAAC TATGTTGTCAGGGGCAATGCCCGTCTGCCTGTAAAATGGATGGCCCCCGAAAGCCTGTTTGAAGGCATCTACACCATTAAGAGTGATGTC TGGTCATATGGAATATTACTGTGGGAAATCTTCTCACTTGGTGTGAATCCTTACCCTGGCATTCCGGTTGATGCTAACTTCTACAAACTG ATTCAAAATGGATTTAAAATGGATCAGCCATTTTATGCTACAGAAGAAATATACATTATAATGCAATCCTGCTGGGCTTTTGACTCAAGG AAACGGCCATCCTTCCCTAATTTGACTTCGTTTTTAGGATGTCAGCTGGCAGATGCAGAAGAAGCGATGTATCAGAATGTGGATGGCCGT GTTTCGGAATGTCCTCACACCTACCAAAACAGGCGACCTTTCAGCAGAGAGATGGATTTGGGGCTACTCTCTCCGCAGGCTCAGGTCGAA >In-frame_PAN3_ENST00000399613_chr13_28794515_+_FLT3_ENST00000380982_chr13_28644749_-_3348nt ATGGATGGAGGTGCTTTAACTGATACAAGTCTCACAGATTCCTATTTTAGCACCAGCTTTATTGGAGTCAATGGATTTGGAAGCCCTGTA GAAACAAAATATCCCCTGATGCAGAGAATGACTAATAGTAGCAGCTCCCCAAGCCTTCTAAATGACAGTGCCAAGCCATATTCAGCCCAT GATCCTCTAACATCACCTGCTTCATCCTTGTTTAATGACTTTGGTGCCCTCAACATCTCTCAGAGACGAAAGACACCAAATCCTACTGCA AGCGAGTTTATTCCTAAAGGAGGATCAACCTCCAGGCTGAGTAACGTGTCCCAGTCAAATATGTCTGCCTTCTCTCAAGTTTTCTCTCAC CCATCCATGGGAAGCCCTGCTACTGCTGGATTAGCGCCAGTTGTTTTTTCTGCAATGATATTTGGGACTATTACAAATCAAGATCTGCCT GTGATCAAGTGTGTTTTAATCAATCATAAGAACAATGATTCATCAGTGGGGAAGTCATCATCATATCCCATGGTATCAGAATCCCCGGAA GACCTCGGGTGTGCGTTGAGACCCCAGAGCTCAGGGACAGTGTACGAAGCTGCCGCTGTGGAAGTGGATGTATCTGCTTCCATCACACTG CAAGTGCTGGTCGACGCCCCAGGGAACATTTCCTGTCTCTGGGTCTTTAAGCACAGCTCCCTGAATTGCCAGCCACATTTTGATTTACAA AACAGAGGAGTTGTTTCCATGGTCATTTTGAAAATGACAGAAACCCAAGCTGGAGAATACCTACTTTTTATTCAGAGTGAAGCTACCAAT TACACAATATTGTTTACAGTGAGTATAAGAAATACCCTGCTTTACACATTAAGAAGACCTTACTTTAGAAAAATGGAAAACCAGGACGCC CTGGTCTGCATATCTGAGAGCGTTCCAGAGCCGATCGTGGAATGGGTGCTTTGCGATTCACAGGGGGAAAGCTGTAAAGAAGAAAGTCCA GCTGTTGTTAAAAAGGAGGAAAAAGTGCTTCATGAATTATTTGGGACGGACATAAGGTGCTGTGCCAGAAATGAACTGGGCAGGGAATGC ACCAGGCTGTTCACAATAGATCTAAATCAAACTCCTCAGACCACATTGCCACAATTATTTCTTAAAGTAGGGGAACCCTTATGGATAAGG TGCAAAGCTGTTCATGTGAACCATGGATTCGGGCTCACCTGGGAATTAGAAAACAAAGCACTCGAGGAGGGCAACTACTTTGAGATGAGT ACCTATTCAACAAACAGAACTATGATACGGATTCTGTTTGCTTTTGTATCATCAGTGGCAAGAAACGACACCGGATACTACACTTGTTCC TCTTCAAAGCATCCCAGTCAATCAGCTTTGGTTACCATCGTAGAAAAGGGATTTATAAATGCTACCAATTCAAGTGAAGATTATGAAATT GACCAATATGAAGAGTTTTGTTTTTCTGTCAGGTTTAAAGCCTACCCACAAATCAGATGTACGTGGACCTTCTCTCGAAAATCATTTCCT TGTGAGCAAAAGGGTCTTGATAACGGATACAGCATATCCAAGTTTTGCAATCATAAGCACCAGCCAGGAGAATATATATTCCATGCAGAA AATGATGATGCCCAATTTACCAAAATGTTCACGCTGAATATAAGAAGGAAACCTCAAGTGCTCGCAGAAGCATCGGCAAGTCAGGCGTCC TGTTTCTCGGATGGATACCCATTACCATCTTGGACCTGGAAGAAGTGTTCAGACAAGTCTCCCAACTGCACAGAAGAGATCACAGAAGGA GTCTGGAATAGAAAGGCTAACAGAAAAGTGTTTGGACAGTGGGTGTCGAGCAGTACTCTAAACATGAGTGAAGCCATAAAAGGGTTCCTG GTCAAGTGCTGTGCATACAATTCCCTTGGCACATCTTGTGAGACGATCCTTTTAAACTCTCCAGGCCCCTTCCCTTTCATCCAAGACAAC ATCTCATTCTATGCAACAATTGGTGTTTGTCTCCTCTTCATTGTCGTTTTAACCCTGCTAATTTGTCACAAGTACAAAAAGCAATTTAGG TATGAAAGCCAGCTACAGATGGTACAGGTGACCGGCTCCTCAGATAATGAGTACTTCTACGTTGATTTCAGAGAATATGAATATGATCTC AAATGGGAGTTTCCAAGAGAAAATTTAGAGTTTGGGAAGGTACTAGGATCAGGTGCTTTTGGAAAAGTGATGAACGCAACAGCTTATGGA ATTAGCAAAACAGGAGTCTCAATCCAGGTTGCCGTCAAAATGCTGAAAGAAAAAGCAGACAGCTCTGAAAGAGAGGCACTCATGTCAGAA CTCAAGATGATGACCCAGCTGGGAAGCCACGAGAATATTGTGAACCTGCTGGGGGCGTGCACACTGTCAGGACCAATTTACTTGATTTTT GAATACTGTTGCTATGGTGATCTTCTCAACTATCTAAGAAGTAAAAGAGAAAAATTTCACAGGACTTGGACAGAGATTTTCAAGGAACAC AATTTCAGTTTTTACCCCACTTTCCAATCACATCCAAATTCCAGCATGCCTGGTTCAAGAGAAGTTCAGATACACCCGGACTCGGATCAA ATCTCAGGGCTTCATGGGAATTCATTTCACTCTGAAGATGAAATTGAATATGAAAACCAAAAAAGGCTGGAAGAAGAGGAGGACTTGAAT GTGCTTACATTTGAAGATCTTCTTTGCTTTGCATATCAAGTTGCCAAAGGAATGGAATTTCTGGAATTTAAGTCGTGTGTTCACAGAGAC CTGGCCGCCAGGAACGTGCTTGTCACCCACGGGAAAGTGGTGAAGATATGTGACTTTGGATTGGCTCGAGATATCATGAGTGATTCCAAC TATGTTGTCAGGGGCAATGTGAGGCTGGCCCGTCTGCCTGTAAAATGGATGGCCCCCGAAAGCCTGTTTGAAGGCATCTACACCATTAAG AGTGATGTCTGGTCATATGGAATATTACTGTGGGAAATCTTCTCACTTGGTGTGAATCCTTACCCTGGCATTCCGGTTGATGCTAACTTC TACAAACTGATTCAAAATGGATTTAAAATGGATCAGCCATTTTATGCTACAGAAGAAATATACATTATAATGCAATCCTGCTGGGCTTTT GACTCAAGGAAACGGCCATCCTTCCCTAATTTGACTTCGTTTTTAGGATGTCAGCTGGCAGATGCAGAAGAAGCGATGTATCAGAATGTG GATGGCCGTGTTTCGGAATGTCCTCACACCTACCAAAACAGGCGACCTTTCAGCAGAGAGATGGATTTGGGGCTACTCTCTCCGCAGGCT >In-frame_PAN3_ENST00000399613_chr13_28794515_+_FLT3_ENST00000537084_chr13_28644749_-_3216nt ATGGATGGAGGTGCTTTAACTGATACAAGTCTCACAGATTCCTATTTTAGCACCAGCTTTATTGGAGTCAATGGATTTGGAAGCCCTGTA GAAACAAAATATCCCCTGATGCAGAGAATGACTAATAGTAGCAGCTCCCCAAGCCTTCTAAATGACAGTGCCAAGCCATATTCAGCCCAT GATCCTCTAACATCACCTGCTTCATCCTTGTTTAATGACTTTGGTGCCCTCAACATCTCTCAGAGACGAAAGACACCAAATCCTACTGCA AGCGAGTTTATTCCTAAAGGAGGATCAACCTCCAGGCTGAGTAACGTGTCCCAGTCAAATATGTCTGCCTTCTCTCAAGTTTTCTCTCAC CCATCCATGGGAAGCCCTGCTACTGCTGGATTAGCGCCAGTTGTTTTTTCTGCAATGATATTTGGGACTATTACAAATCAAGATCTGCCT GTGATCAAGTGTGTTTTAATCAATCATAAGAACAATGATTCATCAGTGGGGAAGTCATCATCATATCCCATGGTATCAGAATCCCCGGAA GACCTCGGGTGTGCGTTGAGACCCCAGAGCTCAGGGACAGTGTACGAAGCTGCCGCTGTGGAAGTGGATGTATCTGCTTCCATCACACTG CAAGTGCTGGTCGACGCCCCAGGGAACATTTCCTGTCTCTGGGTCTTTAAGCACAGCTCCCTGAATTGCCAGCCACATTTTGATTTACAA AACAGAGGAGTTGTTTCCATGGTCATTTTGAAAATGACAGAAACCCAAGCTGGAGAATACCTACTTTTTATTCAGAGTGAAGCTACCAAT TACACAATATTGTTTACAGTGAGTATAAGAAATACCCTGCTTTACACATTAAGAAGACCTTACTTTAGAAAAATGGAAAACCAGGACGCC CTGGTCTGCATATCTGAGAGCGTTCCAGAGCCGATCGTGGAATGGGTGCTTTGCGATTCACAGGGGGAAAGCTGTAAAGAAGAAAGTCCA GCTGTTGTTAAAAAGGAGGAAAAAGTGCTTCATGAATTATTTGGGACGGACATAAGGTGCTGTGCCAGAAATGAACTGGGCAGGGAATGC ACCAGGCTGTTCACAATAGATCTAAATCAAACTCCTCAGACCACATTGCCACAATTATTTCTTAAAGTAGGGGAACCCTTATGGATAAGG TGCAAAGCTGTTCATGTGAACCATGGATTCGGGCTCACCTGGGAATTAGAAAACAAAGCACTCGAGGAGGGCAACTACTTTGAGATGAGT ACCTATTCAACAAACAGAACTATGATACGGATTCTGTTTGCTTTTGTATCATCAGTGGCAAGAAACGACACCGGATACTACACTTGTTCC TCTTCAAAGCATCCCAGTCAATCAGCTTTGGTTACCATCGTAGAAAAGGGATTTATAAATGCTACCAATTCAAGTGAAGATTATGAAATT GACCAATATGAAGAGTTTTGTTTTTCTGTCAGGTTTAAAGCCTACCCACAAATCAGATGTACGTGGACCTTCTCTCGAAAATCATTTCCT TGTGAGCAAAAGGGTCTTGATAACGGATACAGCATATCCAAGTTTTGCAATCATAAGCACCAGCCAGGAGAATATATATTCCATGCAGAA AATGATGATGCCCAATTTACCAAAATGTTCACGCTGAATATAAGAAGGAAACCTCAAGTGCTCGCAGAAGCATCGGCAAGTCAGGCGTCC TGTTTCTCGGATGGATACCCATTACCATCTTGGACCTGGAAGAAGTGTTCAGACAAGTCTCCCAACTGCACAGAAGAGATCACAGAAGGA GTCTGGAATAGAAAGGCTAACAGAAAAGTGTTTGGACAGTGGGTGTCGAGCAGTACTCTAAACATGAGTGAAGCCATAAAAGGGTTCCTG GTCAAGTGCTGTGCATACAATTCCCTTGGCACATCTTGTGAGACGATCCTTTTAAACTCTCCAGGCCCCTTCCCTTTCATCCAAGACAAC ATCTCATTCTATGCAACAATTGGTGTTTGTCTCCTCTTCATTGTCGTTTTAACCCTGCTAATTTGTCACAAGTACAAAAAGCAATTTAGG TATGAAAGCCAGCTACAGATGGTACAGGTGACCGGCTCCTCAGATAATGAGTACTTCTACGTTGATTTCAGAGAATATGAATATGATCTC AAATGGGAGTTTCCAAGAGAAAATTTAGAGTTTGGGAAGGTACTAGGATCAGGTGCTTTTGGAAAAGTGATGAACGCAACAGCTTATGGA ATTAGCAAAACAGGAGTCTCAATCCAGGTTGCCGTCAAAATGCTGAAAGAAAAAGCAGACAGCTCTGAAAGAGAGGCACTCATGTCAGAA CTCAAGATGATGACCCAGCTGGGAAGCCACGAGAATATTGTGAACCTGCTGGGGGCGTGCACACTGTCAGGACCAATTTACTTGATTTTT GAATACTGTTGCTATGGTGATCTTCTCAACTATCTAAGAAGTAAAAGAGAAAAATTTCACAGGACTTGGACAGAGATTTTCAAGGAACAC AATTTCAGTTTTTACCCCACTTTCCAATCACATCCAAATTCCAGCATGCCTGGTTCAAGAGAAGTTCAGATACACCCGGACTCGGATCAA ATCTCAGGGCTTCATGGGAATTCATTTCACTCTGAAGATGAAATTGAATATGAAAACCAAAAAAGGCTGGAAGAAGAGGAGGACTTGAAT GTGCTTACATTTGAAGATCTTCTTTGCTTTGCATATCAAGTTGCCAAAGGAATGGAATTTCTGGAATTTAAGTCGGCCCGTCTGCCTGTA AAATGGATGGCCCCCGAAAGCCTGTTTGAAGGCATCTACACCATTAAGAGTGATGTCTGGTCATATGGAATATTACTGTGGGAAATCTTC TCACTTGGTGTGAATCCTTACCCTGGCATTCCGGTTGATGCTAACTTCTACAAACTGATTCAAAATGGATTTAAAATGGATCAGCCATTT TATGCTACAGAAGAAATATACATTATAATGCAATCCTGCTGGGCTTTTGACTCAAGGAAACGGCCATCCTTCCCTAATTTGACTTCGTTT TTAGGATGTCAGCTGGCAGATGCAGAAGAAGCGATGTATCAGAATGTGGATGGCCGTGTTTCGGAATGTCCTCACACCTACCAAAACAGG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_PAN3_ENST00000380958_chr13_28794515_+_FLT3_ENST00000241453_chr13_28644749_-_4869nt CTCCCCGGGCGGCTCCGGCTCCCGCAGCGGGACAGACCCACCCGCCCAGGCTTTTATCCGGCACCGGCAGCGTCTTCCTTTCCTCCCCCG TCTATGGTGGTGGCGGCGGCGGCTCCTCGGGCGGCGGCGGAAGACGAGGCTGCGGCGTTGCCATGAACAGTGGCGGCGGCCTCCCGCCCC CCTCGGCCGCCGCCTCCCCTTCCTCCTCCTCGCTGGCGGCGGCGGTGGCGGTGGTGGCCCCGCCGGGGGTCGGGGGTGTCCCCGGCGGGG CGGCGGTAGGAGTGAAGCTGAAGTACTGCCGCTACTACGCTAAGGATAAGACTTGCTTCTACGGGGAGGAGTGTCAGTTCCTGCATGAGG ACCCTGCCGCCGGGGCTGCCCCGGGCCTCGGCCTCCATAGCAACAGCGTCCCCCTGGCTCTGGCTGGTGCACCCGTGGCCGGCTTTCCGC CGGGAGCCGTCGCGGGCGGGGGAGCTGGGCCGCCCCCCGGGCCCAAGAAGCCGGACCTGGGGGACCCGGGGACCGGAGCCGCAGCCGGCG GAGGAGGCAGTAGCGGGGGACTCGATGGACCGCGGCTGGCAATTCCAGGAATGGATGGAGGTGCTTTAACTGATACAAGTCTCACAGATT CCTATTTTAGCACCAGCTTTATTGGAGTCAATGGATTTGGAAGCCCTGTAGAAACAAAATATCCCCTGATGCAGAGAATGACTAATAGTA GCAGCTCCCCAAGCCTTCTAAATGACAGTGCCAAGCCATATTCAGCCCATGATCCTCTAACATCACCTGCTTCATCCTTGTTTAATGACT TTGGTGCCCTCAACATCTCTCAGAGACGAAAGCCAAGGAAGTATCGCCTGGGGATGCTGGAGGAGAGGCTAGTTCCGATGGGATCAAAGG CACGAAAAGCAAAGAACCCTATTGGCTGCCTTGCTGACAGGTGTAAATCAGGAGTACCCATCAATATGGTTTGGTGGAACAGAGTCACAG AAAACAATTTACAGACACCAAATCCTACTGCAAGCGAGTTTATTCCTAAAGGAGGATCAACCTCCAGGCTGAGTAACGTGTCCCAGTCAA ATATGTCTGCCTTCTCTCAAGTTTTCTCTCACCCATCCATGGGAAGCCCTGCTACTGCTGGATTAGCGCCAGTTGTTTTTTCTGCAATGA TATTTGGGACTATTACAAATCAAGATCTGCCTGTGATCAAGTGTGTTTTAATCAATCATAAGAACAATGATTCATCAGTGGGGAAGTCAT CATCATATCCCATGGTATCAGAATCCCCGGAAGACCTCGGGTGTGCGTTGAGACCCCAGAGCTCAGGGACAGTGTACGAAGCTGCCGCTG TGGAAGTGGATGTATCTGCTTCCATCACACTGCAAGTGCTGGTCGACGCCCCAGGGAACATTTCCTGTCTCTGGGTCTTTAAGCACAGCT CCCTGAATTGCCAGCCACATTTTGATTTACAAAACAGAGGAGTTGTTTCCATGGTCATTTTGAAAATGACAGAAACCCAAGCTGGAGAAT ACCTACTTTTTATTCAGAGTGAAGCTACCAATTACACAATATTGTTTACAGTGAGTATAAGAAATACCCTGCTTTACACATTAAGAAGAC CTTACTTTAGAAAAATGGAAAACCAGGACGCCCTGGTCTGCATATCTGAGAGCGTTCCAGAGCCGATCGTGGAATGGGTGCTTTGCGATT CACAGGGGGAAAGCTGTAAAGAAGAAAGTCCAGCTGTTGTTAAAAAGGAGGAAAAAGTGCTTCATGAATTATTTGGGACGGACATAAGGT GCTGTGCCAGAAATGAACTGGGCAGGGAATGCACCAGGCTGTTCACAATAGATCTAAATCAAACTCCTCAGACCACATTGCCACAATTAT TTCTTAAAGTAGGGGAACCCTTATGGATAAGGTGCAAAGCTGTTCATGTGAACCATGGATTCGGGCTCACCTGGGAATTAGAAAACAAAG CACTCGAGGAGGGCAACTACTTTGAGATGAGTACCTATTCAACAAACAGAACTATGATACGGATTCTGTTTGCTTTTGTATCATCAGTGG CAAGAAACGACACCGGATACTACACTTGTTCCTCTTCAAAGCATCCCAGTCAATCAGCTTTGGTTACCATCGTAGAAAAGGGATTTATAA ATGCTACCAATTCAAGTGAAGATTATGAAATTGACCAATATGAAGAGTTTTGTTTTTCTGTCAGGTTTAAAGCCTACCCACAAATCAGAT GTACGTGGACCTTCTCTCGAAAATCATTTCCTTGTGAGCAAAAGGGTCTTGATAACGGATACAGCATATCCAAGTTTTGCAATCATAAGC ACCAGCCAGGAGAATATATATTCCATGCAGAAAATGATGATGCCCAATTTACCAAAATGTTCACGCTGAATATAAGAAGGAAACCTCAAG TGCTCGCAGAAGCATCGGCAAGTCAGGCGTCCTGTTTCTCGGATGGATACCCATTACCATCTTGGACCTGGAAGAAGTGTTCAGACAAGT CTCCCAACTGCACAGAAGAGATCACAGAAGGAGTCTGGAATAGAAAGGCTAACAGAAAAGTGTTTGGACAGTGGGTGTCGAGCAGTACTC TAAACATGAGTGAAGCCATAAAAGGGTTCCTGGTCAAGTGCTGTGCATACAATTCCCTTGGCACATCTTGTGAGACGATCCTTTTAAACT CTCCAGGCCCCTTCCCTTTCATCCAAGACAACATCTCATTCTATGCAACAATTGGTGTTTGTCTCCTCTTCATTGTCGTTTTAACCCTGC TAATTTGTCACAAGTACAAAAAGCAATTTAGGTATGAAAGCCAGCTACAGATGGTACAGGTGACCGGCTCCTCAGATAATGAGTACTTCT ACGTTGATTTCAGAGAATATGAATATGATCTCAAATGGGAGTTTCCAAGAGAAAATTTAGAGTTTGGGAAGGTACTAGGATCAGGTGCTT TTGGAAAAGTGATGAACGCAACAGCTTATGGAATTAGCAAAACAGGAGTCTCAATCCAGGTTGCCGTCAAAATGCTGAAAGAAAAAGCAG ACAGCTCTGAAAGAGAGGCACTCATGTCAGAACTCAAGATGATGACCCAGCTGGGAAGCCACGAGAATATTGTGAACCTGCTGGGGGCGT GCACACTGTCAGGACCAATTTACTTGATTTTTGAATACTGTTGCTATGGTGATCTTCTCAACTATCTAAGAAGTAAAAGAGAAAAATTTC ACAGGACTTGGACAGAGATTTTCAAGGAACACAATTTCAGTTTTTACCCCACTTTCCAATCACATCCAAATTCCAGCATGCCTGGTTCAA GAGAAGTTCAGATACACCCGGACTCGGATCAAATCTCAGGGCTTCATGGGAATTCATTTCACTCTGAAGATGAAATTGAATATGAAAACC AAAAAAGGCTGGAAGAAGAGGAGGACTTGAATGTGCTTACATTTGAAGATCTTCTTTGCTTTGCATATCAAGTTGCCAAAGGAATGGAAT TTCTGGAATTTAAGTCGTGTGTTCACAGAGACCTGGCCGCCAGGAACGTGCTTGTCACCCACGGGAAAGTGGTGAAGATATGTGACTTTG GATTGGCTCGAGATATCATGAGTGATTCCAACTATGTTGTCAGGGGCAATGCCCGTCTGCCTGTAAAATGGATGGCCCCCGAAAGCCTGT TTGAAGGCATCTACACCATTAAGAGTGATGTCTGGTCATATGGAATATTACTGTGGGAAATCTTCTCACTTGGTGTGAATCCTTACCCTG GCATTCCGGTTGATGCTAACTTCTACAAACTGATTCAAAATGGATTTAAAATGGATCAGCCATTTTATGCTACAGAAGAAATATACATTA TAATGCAATCCTGCTGGGCTTTTGACTCAAGGAAACGGCCATCCTTCCCTAATTTGACTTCGTTTTTAGGATGTCAGCTGGCAGATGCAG AAGAAGCGATGTATCAGAATGTGGATGGCCGTGTTTCGGAATGTCCTCACACCTACCAAAACAGGCGACCTTTCAGCAGAGAGATGGATT TGGGGCTACTCTCTCCGCAGGCTCAGGTCGAAGATTCGTAGAGGAACAATTTAGTTTTAAGGACTTCATCCCTCCACCTATCCCTAACAG GCTGTAGATTACCAAAACAAGATTAATTTCATCACTAAAAGAAAATCTATTATCAACTGCTGCTTCACCAGACTTTTCTCTAGAAGCTGT CTGCGTTTACTCTTGTTTTCAAAGGGACTTTTGTAAAATCAAATCATCCTGTCACAAGGCAGGAGGAGCTGATAATGAACTTTATTGGAG CATTGATCTGCATCCAAGGCCTTCTCAGGCTGGCTTGAGTGAATTGTGTACCTGAAGTACAGTATATTCTTGTAAATACATAAAACAAAA GCATTTTGCTAAGGAGAAGCTAATATGATTTTTTAAGTCTATGTTTTAAAATAATATGTAAATTTTTCAGCTATTTAGTGATATATTTTA TGGGTGGGAATAAAATTTCTACTACAGAATTGCCCATTATTGAATTATTTACATGGTATAATTAGGGCAAGTCTTAACTGGAGTTCACGA ACCCCCTGAAATTGTGCACCCATAGCCACCTACACATTCCTTCCAGAGCACGTGTGCTTTTACCCCAAGATACAAGGAATGTGTAGGCAG CTATGGTTGTCACAGCCTAAGATTTCTGCAACAACAGGGGTTGTATTGGGGGAAGTTTATAATGAATAGGTGTTCTACCATAAAGAGTAA TACATCACCTAGACACTTTGGCGGCCTTCCCAGACTCAGGGCCAGTCAGAAGTAACATGGAGGATTAGTATTTTCAATAAAGTTACTCTT >In-frame_PAN3_ENST00000380958_chr13_28794515_+_FLT3_ENST00000380982_chr13_28644749_-_4875nt CTCCCCGGGCGGCTCCGGCTCCCGCAGCGGGACAGACCCACCCGCCCAGGCTTTTATCCGGCACCGGCAGCGTCTTCCTTTCCTCCCCCG TCTATGGTGGTGGCGGCGGCGGCTCCTCGGGCGGCGGCGGAAGACGAGGCTGCGGCGTTGCCATGAACAGTGGCGGCGGCCTCCCGCCCC CCTCGGCCGCCGCCTCCCCTTCCTCCTCCTCGCTGGCGGCGGCGGTGGCGGTGGTGGCCCCGCCGGGGGTCGGGGGTGTCCCCGGCGGGG CGGCGGTAGGAGTGAAGCTGAAGTACTGCCGCTACTACGCTAAGGATAAGACTTGCTTCTACGGGGAGGAGTGTCAGTTCCTGCATGAGG ACCCTGCCGCCGGGGCTGCCCCGGGCCTCGGCCTCCATAGCAACAGCGTCCCCCTGGCTCTGGCTGGTGCACCCGTGGCCGGCTTTCCGC CGGGAGCCGTCGCGGGCGGGGGAGCTGGGCCGCCCCCCGGGCCCAAGAAGCCGGACCTGGGGGACCCGGGGACCGGAGCCGCAGCCGGCG GAGGAGGCAGTAGCGGGGGACTCGATGGACCGCGGCTGGCAATTCCAGGAATGGATGGAGGTGCTTTAACTGATACAAGTCTCACAGATT CCTATTTTAGCACCAGCTTTATTGGAGTCAATGGATTTGGAAGCCCTGTAGAAACAAAATATCCCCTGATGCAGAGAATGACTAATAGTA GCAGCTCCCCAAGCCTTCTAAATGACAGTGCCAAGCCATATTCAGCCCATGATCCTCTAACATCACCTGCTTCATCCTTGTTTAATGACT TTGGTGCCCTCAACATCTCTCAGAGACGAAAGCCAAGGAAGTATCGCCTGGGGATGCTGGAGGAGAGGCTAGTTCCGATGGGATCAAAGG CACGAAAAGCAAAGAACCCTATTGGCTGCCTTGCTGACAGGTGTAAATCAGGAGTACCCATCAATATGGTTTGGTGGAACAGAGTCACAG AAAACAATTTACAGACACCAAATCCTACTGCAAGCGAGTTTATTCCTAAAGGAGGATCAACCTCCAGGCTGAGTAACGTGTCCCAGTCAA ATATGTCTGCCTTCTCTCAAGTTTTCTCTCACCCATCCATGGGAAGCCCTGCTACTGCTGGATTAGCGCCAGTTGTTTTTTCTGCAATGA TATTTGGGACTATTACAAATCAAGATCTGCCTGTGATCAAGTGTGTTTTAATCAATCATAAGAACAATGATTCATCAGTGGGGAAGTCAT CATCATATCCCATGGTATCAGAATCCCCGGAAGACCTCGGGTGTGCGTTGAGACCCCAGAGCTCAGGGACAGTGTACGAAGCTGCCGCTG TGGAAGTGGATGTATCTGCTTCCATCACACTGCAAGTGCTGGTCGACGCCCCAGGGAACATTTCCTGTCTCTGGGTCTTTAAGCACAGCT CCCTGAATTGCCAGCCACATTTTGATTTACAAAACAGAGGAGTTGTTTCCATGGTCATTTTGAAAATGACAGAAACCCAAGCTGGAGAAT ACCTACTTTTTATTCAGAGTGAAGCTACCAATTACACAATATTGTTTACAGTGAGTATAAGAAATACCCTGCTTTACACATTAAGAAGAC CTTACTTTAGAAAAATGGAAAACCAGGACGCCCTGGTCTGCATATCTGAGAGCGTTCCAGAGCCGATCGTGGAATGGGTGCTTTGCGATT CACAGGGGGAAAGCTGTAAAGAAGAAAGTCCAGCTGTTGTTAAAAAGGAGGAAAAAGTGCTTCATGAATTATTTGGGACGGACATAAGGT GCTGTGCCAGAAATGAACTGGGCAGGGAATGCACCAGGCTGTTCACAATAGATCTAAATCAAACTCCTCAGACCACATTGCCACAATTAT TTCTTAAAGTAGGGGAACCCTTATGGATAAGGTGCAAAGCTGTTCATGTGAACCATGGATTCGGGCTCACCTGGGAATTAGAAAACAAAG CACTCGAGGAGGGCAACTACTTTGAGATGAGTACCTATTCAACAAACAGAACTATGATACGGATTCTGTTTGCTTTTGTATCATCAGTGG CAAGAAACGACACCGGATACTACACTTGTTCCTCTTCAAAGCATCCCAGTCAATCAGCTTTGGTTACCATCGTAGAAAAGGGATTTATAA ATGCTACCAATTCAAGTGAAGATTATGAAATTGACCAATATGAAGAGTTTTGTTTTTCTGTCAGGTTTAAAGCCTACCCACAAATCAGAT GTACGTGGACCTTCTCTCGAAAATCATTTCCTTGTGAGCAAAAGGGTCTTGATAACGGATACAGCATATCCAAGTTTTGCAATCATAAGC ACCAGCCAGGAGAATATATATTCCATGCAGAAAATGATGATGCCCAATTTACCAAAATGTTCACGCTGAATATAAGAAGGAAACCTCAAG TGCTCGCAGAAGCATCGGCAAGTCAGGCGTCCTGTTTCTCGGATGGATACCCATTACCATCTTGGACCTGGAAGAAGTGTTCAGACAAGT CTCCCAACTGCACAGAAGAGATCACAGAAGGAGTCTGGAATAGAAAGGCTAACAGAAAAGTGTTTGGACAGTGGGTGTCGAGCAGTACTC TAAACATGAGTGAAGCCATAAAAGGGTTCCTGGTCAAGTGCTGTGCATACAATTCCCTTGGCACATCTTGTGAGACGATCCTTTTAAACT CTCCAGGCCCCTTCCCTTTCATCCAAGACAACATCTCATTCTATGCAACAATTGGTGTTTGTCTCCTCTTCATTGTCGTTTTAACCCTGC TAATTTGTCACAAGTACAAAAAGCAATTTAGGTATGAAAGCCAGCTACAGATGGTACAGGTGACCGGCTCCTCAGATAATGAGTACTTCT ACGTTGATTTCAGAGAATATGAATATGATCTCAAATGGGAGTTTCCAAGAGAAAATTTAGAGTTTGGGAAGGTACTAGGATCAGGTGCTT TTGGAAAAGTGATGAACGCAACAGCTTATGGAATTAGCAAAACAGGAGTCTCAATCCAGGTTGCCGTCAAAATGCTGAAAGAAAAAGCAG ACAGCTCTGAAAGAGAGGCACTCATGTCAGAACTCAAGATGATGACCCAGCTGGGAAGCCACGAGAATATTGTGAACCTGCTGGGGGCGT GCACACTGTCAGGACCAATTTACTTGATTTTTGAATACTGTTGCTATGGTGATCTTCTCAACTATCTAAGAAGTAAAAGAGAAAAATTTC ACAGGACTTGGACAGAGATTTTCAAGGAACACAATTTCAGTTTTTACCCCACTTTCCAATCACATCCAAATTCCAGCATGCCTGGTTCAA GAGAAGTTCAGATACACCCGGACTCGGATCAAATCTCAGGGCTTCATGGGAATTCATTTCACTCTGAAGATGAAATTGAATATGAAAACC AAAAAAGGCTGGAAGAAGAGGAGGACTTGAATGTGCTTACATTTGAAGATCTTCTTTGCTTTGCATATCAAGTTGCCAAAGGAATGGAAT TTCTGGAATTTAAGTCGTGTGTTCACAGAGACCTGGCCGCCAGGAACGTGCTTGTCACCCACGGGAAAGTGGTGAAGATATGTGACTTTG GATTGGCTCGAGATATCATGAGTGATTCCAACTATGTTGTCAGGGGCAATGTGAGGCTGGCCCGTCTGCCTGTAAAATGGATGGCCCCCG AAAGCCTGTTTGAAGGCATCTACACCATTAAGAGTGATGTCTGGTCATATGGAATATTACTGTGGGAAATCTTCTCACTTGGTGTGAATC CTTACCCTGGCATTCCGGTTGATGCTAACTTCTACAAACTGATTCAAAATGGATTTAAAATGGATCAGCCATTTTATGCTACAGAAGAAA TATACATTATAATGCAATCCTGCTGGGCTTTTGACTCAAGGAAACGGCCATCCTTCCCTAATTTGACTTCGTTTTTAGGATGTCAGCTGG CAGATGCAGAAGAAGCGATGTATCAGAATGTGGATGGCCGTGTTTCGGAATGTCCTCACACCTACCAAAACAGGCGACCTTTCAGCAGAG AGATGGATTTGGGGCTACTCTCTCCGCAGGCTCAGGTCGAAGATTCGTAGAGGAACAATTTAGTTTTAAGGACTTCATCCCTCCACCTAT CCCTAACAGGCTGTAGATTACCAAAACAAGATTAATTTCATCACTAAAAGAAAATCTATTATCAACTGCTGCTTCACCAGACTTTTCTCT AGAAGCTGTCTGCGTTTACTCTTGTTTTCAAAGGGACTTTTGTAAAATCAAATCATCCTGTCACAAGGCAGGAGGAGCTGATAATGAACT TTATTGGAGCATTGATCTGCATCCAAGGCCTTCTCAGGCTGGCTTGAGTGAATTGTGTACCTGAAGTACAGTATATTCTTGTAAATACAT AAAACAAAAGCATTTTGCTAAGGAGAAGCTAATATGATTTTTTAAGTCTATGTTTTAAAATAATATGTAAATTTTTCAGCTATTTAGTGA TATATTTTATGGGTGGGAATAAAATTTCTACTACAGAATTGCCCATTATTGAATTATTTACATGGTATAATTAGGGCAAGTCTTAACTGG AGTTCACGAACCCCCTGAAATTGTGCACCCATAGCCACCTACACATTCCTTCCAGAGCACGTGTGCTTTTACCCCAAGATACAAGGAATG TGTAGGCAGCTATGGTTGTCACAGCCTAAGATTTCTGCAACAACAGGGGTTGTATTGGGGGAAGTTTATAATGAATAGGTGTTCTACCAT AAAGAGTAATACATCACCTAGACACTTTGGCGGCCTTCCCAGACTCAGGGCCAGTCAGAAGTAACATGGAGGATTAGTATTTTCAATAAA >In-frame_PAN3_ENST00000380958_chr13_28794515_+_FLT3_ENST00000537084_chr13_28644749_-_4227nt CTCCCCGGGCGGCTCCGGCTCCCGCAGCGGGACAGACCCACCCGCCCAGGCTTTTATCCGGCACCGGCAGCGTCTTCCTTTCCTCCCCCG TCTATGGTGGTGGCGGCGGCGGCTCCTCGGGCGGCGGCGGAAGACGAGGCTGCGGCGTTGCCATGAACAGTGGCGGCGGCCTCCCGCCCC CCTCGGCCGCCGCCTCCCCTTCCTCCTCCTCGCTGGCGGCGGCGGTGGCGGTGGTGGCCCCGCCGGGGGTCGGGGGTGTCCCCGGCGGGG CGGCGGTAGGAGTGAAGCTGAAGTACTGCCGCTACTACGCTAAGGATAAGACTTGCTTCTACGGGGAGGAGTGTCAGTTCCTGCATGAGG ACCCTGCCGCCGGGGCTGCCCCGGGCCTCGGCCTCCATAGCAACAGCGTCCCCCTGGCTCTGGCTGGTGCACCCGTGGCCGGCTTTCCGC CGGGAGCCGTCGCGGGCGGGGGAGCTGGGCCGCCCCCCGGGCCCAAGAAGCCGGACCTGGGGGACCCGGGGACCGGAGCCGCAGCCGGCG GAGGAGGCAGTAGCGGGGGACTCGATGGACCGCGGCTGGCAATTCCAGGAATGGATGGAGGTGCTTTAACTGATACAAGTCTCACAGATT CCTATTTTAGCACCAGCTTTATTGGAGTCAATGGATTTGGAAGCCCTGTAGAAACAAAATATCCCCTGATGCAGAGAATGACTAATAGTA GCAGCTCCCCAAGCCTTCTAAATGACAGTGCCAAGCCATATTCAGCCCATGATCCTCTAACATCACCTGCTTCATCCTTGTTTAATGACT TTGGTGCCCTCAACATCTCTCAGAGACGAAAGCCAAGGAAGTATCGCCTGGGGATGCTGGAGGAGAGGCTAGTTCCGATGGGATCAAAGG CACGAAAAGCAAAGAACCCTATTGGCTGCCTTGCTGACAGGTGTAAATCAGGAGTACCCATCAATATGGTTTGGTGGAACAGAGTCACAG AAAACAATTTACAGACACCAAATCCTACTGCAAGCGAGTTTATTCCTAAAGGAGGATCAACCTCCAGGCTGAGTAACGTGTCCCAGTCAA ATATGTCTGCCTTCTCTCAAGTTTTCTCTCACCCATCCATGGGAAGCCCTGCTACTGCTGGATTAGCGCCAGTTGTTTTTTCTGCAATGA TATTTGGGACTATTACAAATCAAGATCTGCCTGTGATCAAGTGTGTTTTAATCAATCATAAGAACAATGATTCATCAGTGGGGAAGTCAT CATCATATCCCATGGTATCAGAATCCCCGGAAGACCTCGGGTGTGCGTTGAGACCCCAGAGCTCAGGGACAGTGTACGAAGCTGCCGCTG TGGAAGTGGATGTATCTGCTTCCATCACACTGCAAGTGCTGGTCGACGCCCCAGGGAACATTTCCTGTCTCTGGGTCTTTAAGCACAGCT CCCTGAATTGCCAGCCACATTTTGATTTACAAAACAGAGGAGTTGTTTCCATGGTCATTTTGAAAATGACAGAAACCCAAGCTGGAGAAT ACCTACTTTTTATTCAGAGTGAAGCTACCAATTACACAATATTGTTTACAGTGAGTATAAGAAATACCCTGCTTTACACATTAAGAAGAC CTTACTTTAGAAAAATGGAAAACCAGGACGCCCTGGTCTGCATATCTGAGAGCGTTCCAGAGCCGATCGTGGAATGGGTGCTTTGCGATT CACAGGGGGAAAGCTGTAAAGAAGAAAGTCCAGCTGTTGTTAAAAAGGAGGAAAAAGTGCTTCATGAATTATTTGGGACGGACATAAGGT GCTGTGCCAGAAATGAACTGGGCAGGGAATGCACCAGGCTGTTCACAATAGATCTAAATCAAACTCCTCAGACCACATTGCCACAATTAT TTCTTAAAGTAGGGGAACCCTTATGGATAAGGTGCAAAGCTGTTCATGTGAACCATGGATTCGGGCTCACCTGGGAATTAGAAAACAAAG CACTCGAGGAGGGCAACTACTTTGAGATGAGTACCTATTCAACAAACAGAACTATGATACGGATTCTGTTTGCTTTTGTATCATCAGTGG CAAGAAACGACACCGGATACTACACTTGTTCCTCTTCAAAGCATCCCAGTCAATCAGCTTTGGTTACCATCGTAGAAAAGGGATTTATAA ATGCTACCAATTCAAGTGAAGATTATGAAATTGACCAATATGAAGAGTTTTGTTTTTCTGTCAGGTTTAAAGCCTACCCACAAATCAGAT GTACGTGGACCTTCTCTCGAAAATCATTTCCTTGTGAGCAAAAGGGTCTTGATAACGGATACAGCATATCCAAGTTTTGCAATCATAAGC ACCAGCCAGGAGAATATATATTCCATGCAGAAAATGATGATGCCCAATTTACCAAAATGTTCACGCTGAATATAAGAAGGAAACCTCAAG TGCTCGCAGAAGCATCGGCAAGTCAGGCGTCCTGTTTCTCGGATGGATACCCATTACCATCTTGGACCTGGAAGAAGTGTTCAGACAAGT CTCCCAACTGCACAGAAGAGATCACAGAAGGAGTCTGGAATAGAAAGGCTAACAGAAAAGTGTTTGGACAGTGGGTGTCGAGCAGTACTC TAAACATGAGTGAAGCCATAAAAGGGTTCCTGGTCAAGTGCTGTGCATACAATTCCCTTGGCACATCTTGTGAGACGATCCTTTTAAACT CTCCAGGCCCCTTCCCTTTCATCCAAGACAACATCTCATTCTATGCAACAATTGGTGTTTGTCTCCTCTTCATTGTCGTTTTAACCCTGC TAATTTGTCACAAGTACAAAAAGCAATTTAGGTATGAAAGCCAGCTACAGATGGTACAGGTGACCGGCTCCTCAGATAATGAGTACTTCT ACGTTGATTTCAGAGAATATGAATATGATCTCAAATGGGAGTTTCCAAGAGAAAATTTAGAGTTTGGGAAGGTACTAGGATCAGGTGCTT TTGGAAAAGTGATGAACGCAACAGCTTATGGAATTAGCAAAACAGGAGTCTCAATCCAGGTTGCCGTCAAAATGCTGAAAGAAAAAGCAG ACAGCTCTGAAAGAGAGGCACTCATGTCAGAACTCAAGATGATGACCCAGCTGGGAAGCCACGAGAATATTGTGAACCTGCTGGGGGCGT GCACACTGTCAGGACCAATTTACTTGATTTTTGAATACTGTTGCTATGGTGATCTTCTCAACTATCTAAGAAGTAAAAGAGAAAAATTTC ACAGGACTTGGACAGAGATTTTCAAGGAACACAATTTCAGTTTTTACCCCACTTTCCAATCACATCCAAATTCCAGCATGCCTGGTTCAA GAGAAGTTCAGATACACCCGGACTCGGATCAAATCTCAGGGCTTCATGGGAATTCATTTCACTCTGAAGATGAAATTGAATATGAAAACC AAAAAAGGCTGGAAGAAGAGGAGGACTTGAATGTGCTTACATTTGAAGATCTTCTTTGCTTTGCATATCAAGTTGCCAAAGGAATGGAAT TTCTGGAATTTAAGTCGGCCCGTCTGCCTGTAAAATGGATGGCCCCCGAAAGCCTGTTTGAAGGCATCTACACCATTAAGAGTGATGTCT GGTCATATGGAATATTACTGTGGGAAATCTTCTCACTTGGTGTGAATCCTTACCCTGGCATTCCGGTTGATGCTAACTTCTACAAACTGA TTCAAAATGGATTTAAAATGGATCAGCCATTTTATGCTACAGAAGAAATATACATTATAATGCAATCCTGCTGGGCTTTTGACTCAAGGA AACGGCCATCCTTCCCTAATTTGACTTCGTTTTTAGGATGTCAGCTGGCAGATGCAGAAGAAGCGATGTATCAGAATGTGGATGGCCGTG TTTCGGAATGTCCTCACACCTACCAAAACAGGCGACCTTTCAGCAGAGAGATGGATTTGGGGCTACTCTCTCCGCAGGCTCAGGTCGAAG ATTCGTAGAGGAACAATTTAGTTTTAAGGACTTCATCCCTCCACCTATCCCTAACAGGCTGTAGATTACCAAAACAAGATTAATTTCATC ACTAAAAGAAAATCTATTATCAACTGCTGCTTCACCAGACTTTTCTCTAGAAGCTGTCTGCGTTTACTCTTGTTTTCAAAGGGACTTTTG >In-frame_PAN3_ENST00000399613_chr13_28794515_+_FLT3_ENST00000241453_chr13_28644749_-_4180nt GCCGCAGCCGGCGGAGGAGGCAGTAGCGGGGGACTCGATGGACCGCGGCTGGCAATTCCAGGAATGGATGGAGGTGCTTTAACTGATACA AGTCTCACAGATTCCTATTTTAGCACCAGCTTTATTGGAGTCAATGGATTTGGAAGCCCTGTAGAAACAAAATATCCCCTGATGCAGAGA ATGACTAATAGTAGCAGCTCCCCAAGCCTTCTAAATGACAGTGCCAAGCCATATTCAGCCCATGATCCTCTAACATCACCTGCTTCATCC TTGTTTAATGACTTTGGTGCCCTCAACATCTCTCAGAGACGAAAGACACCAAATCCTACTGCAAGCGAGTTTATTCCTAAAGGAGGATCA ACCTCCAGGCTGAGTAACGTGTCCCAGTCAAATATGTCTGCCTTCTCTCAAGTTTTCTCTCACCCATCCATGGGAAGCCCTGCTACTGCT GGATTAGCGCCAGTTGTTTTTTCTGCAATGATATTTGGGACTATTACAAATCAAGATCTGCCTGTGATCAAGTGTGTTTTAATCAATCAT AAGAACAATGATTCATCAGTGGGGAAGTCATCATCATATCCCATGGTATCAGAATCCCCGGAAGACCTCGGGTGTGCGTTGAGACCCCAG AGCTCAGGGACAGTGTACGAAGCTGCCGCTGTGGAAGTGGATGTATCTGCTTCCATCACACTGCAAGTGCTGGTCGACGCCCCAGGGAAC ATTTCCTGTCTCTGGGTCTTTAAGCACAGCTCCCTGAATTGCCAGCCACATTTTGATTTACAAAACAGAGGAGTTGTTTCCATGGTCATT TTGAAAATGACAGAAACCCAAGCTGGAGAATACCTACTTTTTATTCAGAGTGAAGCTACCAATTACACAATATTGTTTACAGTGAGTATA AGAAATACCCTGCTTTACACATTAAGAAGACCTTACTTTAGAAAAATGGAAAACCAGGACGCCCTGGTCTGCATATCTGAGAGCGTTCCA GAGCCGATCGTGGAATGGGTGCTTTGCGATTCACAGGGGGAAAGCTGTAAAGAAGAAAGTCCAGCTGTTGTTAAAAAGGAGGAAAAAGTG CTTCATGAATTATTTGGGACGGACATAAGGTGCTGTGCCAGAAATGAACTGGGCAGGGAATGCACCAGGCTGTTCACAATAGATCTAAAT CAAACTCCTCAGACCACATTGCCACAATTATTTCTTAAAGTAGGGGAACCCTTATGGATAAGGTGCAAAGCTGTTCATGTGAACCATGGA TTCGGGCTCACCTGGGAATTAGAAAACAAAGCACTCGAGGAGGGCAACTACTTTGAGATGAGTACCTATTCAACAAACAGAACTATGATA CGGATTCTGTTTGCTTTTGTATCATCAGTGGCAAGAAACGACACCGGATACTACACTTGTTCCTCTTCAAAGCATCCCAGTCAATCAGCT TTGGTTACCATCGTAGAAAAGGGATTTATAAATGCTACCAATTCAAGTGAAGATTATGAAATTGACCAATATGAAGAGTTTTGTTTTTCT GTCAGGTTTAAAGCCTACCCACAAATCAGATGTACGTGGACCTTCTCTCGAAAATCATTTCCTTGTGAGCAAAAGGGTCTTGATAACGGA TACAGCATATCCAAGTTTTGCAATCATAAGCACCAGCCAGGAGAATATATATTCCATGCAGAAAATGATGATGCCCAATTTACCAAAATG TTCACGCTGAATATAAGAAGGAAACCTCAAGTGCTCGCAGAAGCATCGGCAAGTCAGGCGTCCTGTTTCTCGGATGGATACCCATTACCA TCTTGGACCTGGAAGAAGTGTTCAGACAAGTCTCCCAACTGCACAGAAGAGATCACAGAAGGAGTCTGGAATAGAAAGGCTAACAGAAAA GTGTTTGGACAGTGGGTGTCGAGCAGTACTCTAAACATGAGTGAAGCCATAAAAGGGTTCCTGGTCAAGTGCTGTGCATACAATTCCCTT GGCACATCTTGTGAGACGATCCTTTTAAACTCTCCAGGCCCCTTCCCTTTCATCCAAGACAACATCTCATTCTATGCAACAATTGGTGTT TGTCTCCTCTTCATTGTCGTTTTAACCCTGCTAATTTGTCACAAGTACAAAAAGCAATTTAGGTATGAAAGCCAGCTACAGATGGTACAG GTGACCGGCTCCTCAGATAATGAGTACTTCTACGTTGATTTCAGAGAATATGAATATGATCTCAAATGGGAGTTTCCAAGAGAAAATTTA GAGTTTGGGAAGGTACTAGGATCAGGTGCTTTTGGAAAAGTGATGAACGCAACAGCTTATGGAATTAGCAAAACAGGAGTCTCAATCCAG GTTGCCGTCAAAATGCTGAAAGAAAAAGCAGACAGCTCTGAAAGAGAGGCACTCATGTCAGAACTCAAGATGATGACCCAGCTGGGAAGC CACGAGAATATTGTGAACCTGCTGGGGGCGTGCACACTGTCAGGACCAATTTACTTGATTTTTGAATACTGTTGCTATGGTGATCTTCTC AACTATCTAAGAAGTAAAAGAGAAAAATTTCACAGGACTTGGACAGAGATTTTCAAGGAACACAATTTCAGTTTTTACCCCACTTTCCAA TCACATCCAAATTCCAGCATGCCTGGTTCAAGAGAAGTTCAGATACACCCGGACTCGGATCAAATCTCAGGGCTTCATGGGAATTCATTT CACTCTGAAGATGAAATTGAATATGAAAACCAAAAAAGGCTGGAAGAAGAGGAGGACTTGAATGTGCTTACATTTGAAGATCTTCTTTGC TTTGCATATCAAGTTGCCAAAGGAATGGAATTTCTGGAATTTAAGTCGTGTGTTCACAGAGACCTGGCCGCCAGGAACGTGCTTGTCACC CACGGGAAAGTGGTGAAGATATGTGACTTTGGATTGGCTCGAGATATCATGAGTGATTCCAACTATGTTGTCAGGGGCAATGCCCGTCTG CCTGTAAAATGGATGGCCCCCGAAAGCCTGTTTGAAGGCATCTACACCATTAAGAGTGATGTCTGGTCATATGGAATATTACTGTGGGAA ATCTTCTCACTTGGTGTGAATCCTTACCCTGGCATTCCGGTTGATGCTAACTTCTACAAACTGATTCAAAATGGATTTAAAATGGATCAG CCATTTTATGCTACAGAAGAAATATACATTATAATGCAATCCTGCTGGGCTTTTGACTCAAGGAAACGGCCATCCTTCCCTAATTTGACT TCGTTTTTAGGATGTCAGCTGGCAGATGCAGAAGAAGCGATGTATCAGAATGTGGATGGCCGTGTTTCGGAATGTCCTCACACCTACCAA AACAGGCGACCTTTCAGCAGAGAGATGGATTTGGGGCTACTCTCTCCGCAGGCTCAGGTCGAAGATTCGTAGAGGAACAATTTAGTTTTA AGGACTTCATCCCTCCACCTATCCCTAACAGGCTGTAGATTACCAAAACAAGATTAATTTCATCACTAAAAGAAAATCTATTATCAACTG CTGCTTCACCAGACTTTTCTCTAGAAGCTGTCTGCGTTTACTCTTGTTTTCAAAGGGACTTTTGTAAAATCAAATCATCCTGTCACAAGG CAGGAGGAGCTGATAATGAACTTTATTGGAGCATTGATCTGCATCCAAGGCCTTCTCAGGCTGGCTTGAGTGAATTGTGTACCTGAAGTA CAGTATATTCTTGTAAATACATAAAACAAAAGCATTTTGCTAAGGAGAAGCTAATATGATTTTTTAAGTCTATGTTTTAAAATAATATGT AAATTTTTCAGCTATTTAGTGATATATTTTATGGGTGGGAATAAAATTTCTACTACAGAATTGCCCATTATTGAATTATTTACATGGTAT AATTAGGGCAAGTCTTAACTGGAGTTCACGAACCCCCTGAAATTGTGCACCCATAGCCACCTACACATTCCTTCCAGAGCACGTGTGCTT TTACCCCAAGATACAAGGAATGTGTAGGCAGCTATGGTTGTCACAGCCTAAGATTTCTGCAACAACAGGGGTTGTATTGGGGGAAGTTTA TAATGAATAGGTGTTCTACCATAAAGAGTAATACATCACCTAGACACTTTGGCGGCCTTCCCAGACTCAGGGCCAGTCAGAAGTAACATG >In-frame_PAN3_ENST00000399613_chr13_28794515_+_FLT3_ENST00000380982_chr13_28644749_-_4186nt GCCGCAGCCGGCGGAGGAGGCAGTAGCGGGGGACTCGATGGACCGCGGCTGGCAATTCCAGGAATGGATGGAGGTGCTTTAACTGATACA AGTCTCACAGATTCCTATTTTAGCACCAGCTTTATTGGAGTCAATGGATTTGGAAGCCCTGTAGAAACAAAATATCCCCTGATGCAGAGA ATGACTAATAGTAGCAGCTCCCCAAGCCTTCTAAATGACAGTGCCAAGCCATATTCAGCCCATGATCCTCTAACATCACCTGCTTCATCC TTGTTTAATGACTTTGGTGCCCTCAACATCTCTCAGAGACGAAAGACACCAAATCCTACTGCAAGCGAGTTTATTCCTAAAGGAGGATCA ACCTCCAGGCTGAGTAACGTGTCCCAGTCAAATATGTCTGCCTTCTCTCAAGTTTTCTCTCACCCATCCATGGGAAGCCCTGCTACTGCT GGATTAGCGCCAGTTGTTTTTTCTGCAATGATATTTGGGACTATTACAAATCAAGATCTGCCTGTGATCAAGTGTGTTTTAATCAATCAT AAGAACAATGATTCATCAGTGGGGAAGTCATCATCATATCCCATGGTATCAGAATCCCCGGAAGACCTCGGGTGTGCGTTGAGACCCCAG AGCTCAGGGACAGTGTACGAAGCTGCCGCTGTGGAAGTGGATGTATCTGCTTCCATCACACTGCAAGTGCTGGTCGACGCCCCAGGGAAC ATTTCCTGTCTCTGGGTCTTTAAGCACAGCTCCCTGAATTGCCAGCCACATTTTGATTTACAAAACAGAGGAGTTGTTTCCATGGTCATT TTGAAAATGACAGAAACCCAAGCTGGAGAATACCTACTTTTTATTCAGAGTGAAGCTACCAATTACACAATATTGTTTACAGTGAGTATA AGAAATACCCTGCTTTACACATTAAGAAGACCTTACTTTAGAAAAATGGAAAACCAGGACGCCCTGGTCTGCATATCTGAGAGCGTTCCA GAGCCGATCGTGGAATGGGTGCTTTGCGATTCACAGGGGGAAAGCTGTAAAGAAGAAAGTCCAGCTGTTGTTAAAAAGGAGGAAAAAGTG CTTCATGAATTATTTGGGACGGACATAAGGTGCTGTGCCAGAAATGAACTGGGCAGGGAATGCACCAGGCTGTTCACAATAGATCTAAAT CAAACTCCTCAGACCACATTGCCACAATTATTTCTTAAAGTAGGGGAACCCTTATGGATAAGGTGCAAAGCTGTTCATGTGAACCATGGA TTCGGGCTCACCTGGGAATTAGAAAACAAAGCACTCGAGGAGGGCAACTACTTTGAGATGAGTACCTATTCAACAAACAGAACTATGATA CGGATTCTGTTTGCTTTTGTATCATCAGTGGCAAGAAACGACACCGGATACTACACTTGTTCCTCTTCAAAGCATCCCAGTCAATCAGCT TTGGTTACCATCGTAGAAAAGGGATTTATAAATGCTACCAATTCAAGTGAAGATTATGAAATTGACCAATATGAAGAGTTTTGTTTTTCT GTCAGGTTTAAAGCCTACCCACAAATCAGATGTACGTGGACCTTCTCTCGAAAATCATTTCCTTGTGAGCAAAAGGGTCTTGATAACGGA TACAGCATATCCAAGTTTTGCAATCATAAGCACCAGCCAGGAGAATATATATTCCATGCAGAAAATGATGATGCCCAATTTACCAAAATG TTCACGCTGAATATAAGAAGGAAACCTCAAGTGCTCGCAGAAGCATCGGCAAGTCAGGCGTCCTGTTTCTCGGATGGATACCCATTACCA TCTTGGACCTGGAAGAAGTGTTCAGACAAGTCTCCCAACTGCACAGAAGAGATCACAGAAGGAGTCTGGAATAGAAAGGCTAACAGAAAA GTGTTTGGACAGTGGGTGTCGAGCAGTACTCTAAACATGAGTGAAGCCATAAAAGGGTTCCTGGTCAAGTGCTGTGCATACAATTCCCTT GGCACATCTTGTGAGACGATCCTTTTAAACTCTCCAGGCCCCTTCCCTTTCATCCAAGACAACATCTCATTCTATGCAACAATTGGTGTT TGTCTCCTCTTCATTGTCGTTTTAACCCTGCTAATTTGTCACAAGTACAAAAAGCAATTTAGGTATGAAAGCCAGCTACAGATGGTACAG GTGACCGGCTCCTCAGATAATGAGTACTTCTACGTTGATTTCAGAGAATATGAATATGATCTCAAATGGGAGTTTCCAAGAGAAAATTTA GAGTTTGGGAAGGTACTAGGATCAGGTGCTTTTGGAAAAGTGATGAACGCAACAGCTTATGGAATTAGCAAAACAGGAGTCTCAATCCAG GTTGCCGTCAAAATGCTGAAAGAAAAAGCAGACAGCTCTGAAAGAGAGGCACTCATGTCAGAACTCAAGATGATGACCCAGCTGGGAAGC CACGAGAATATTGTGAACCTGCTGGGGGCGTGCACACTGTCAGGACCAATTTACTTGATTTTTGAATACTGTTGCTATGGTGATCTTCTC AACTATCTAAGAAGTAAAAGAGAAAAATTTCACAGGACTTGGACAGAGATTTTCAAGGAACACAATTTCAGTTTTTACCCCACTTTCCAA TCACATCCAAATTCCAGCATGCCTGGTTCAAGAGAAGTTCAGATACACCCGGACTCGGATCAAATCTCAGGGCTTCATGGGAATTCATTT CACTCTGAAGATGAAATTGAATATGAAAACCAAAAAAGGCTGGAAGAAGAGGAGGACTTGAATGTGCTTACATTTGAAGATCTTCTTTGC TTTGCATATCAAGTTGCCAAAGGAATGGAATTTCTGGAATTTAAGTCGTGTGTTCACAGAGACCTGGCCGCCAGGAACGTGCTTGTCACC CACGGGAAAGTGGTGAAGATATGTGACTTTGGATTGGCTCGAGATATCATGAGTGATTCCAACTATGTTGTCAGGGGCAATGTGAGGCTG GCCCGTCTGCCTGTAAAATGGATGGCCCCCGAAAGCCTGTTTGAAGGCATCTACACCATTAAGAGTGATGTCTGGTCATATGGAATATTA CTGTGGGAAATCTTCTCACTTGGTGTGAATCCTTACCCTGGCATTCCGGTTGATGCTAACTTCTACAAACTGATTCAAAATGGATTTAAA ATGGATCAGCCATTTTATGCTACAGAAGAAATATACATTATAATGCAATCCTGCTGGGCTTTTGACTCAAGGAAACGGCCATCCTTCCCT AATTTGACTTCGTTTTTAGGATGTCAGCTGGCAGATGCAGAAGAAGCGATGTATCAGAATGTGGATGGCCGTGTTTCGGAATGTCCTCAC ACCTACCAAAACAGGCGACCTTTCAGCAGAGAGATGGATTTGGGGCTACTCTCTCCGCAGGCTCAGGTCGAAGATTCGTAGAGGAACAAT TTAGTTTTAAGGACTTCATCCCTCCACCTATCCCTAACAGGCTGTAGATTACCAAAACAAGATTAATTTCATCACTAAAAGAAAATCTAT TATCAACTGCTGCTTCACCAGACTTTTCTCTAGAAGCTGTCTGCGTTTACTCTTGTTTTCAAAGGGACTTTTGTAAAATCAAATCATCCT GTCACAAGGCAGGAGGAGCTGATAATGAACTTTATTGGAGCATTGATCTGCATCCAAGGCCTTCTCAGGCTGGCTTGAGTGAATTGTGTA CCTGAAGTACAGTATATTCTTGTAAATACATAAAACAAAAGCATTTTGCTAAGGAGAAGCTAATATGATTTTTTAAGTCTATGTTTTAAA ATAATATGTAAATTTTTCAGCTATTTAGTGATATATTTTATGGGTGGGAATAAAATTTCTACTACAGAATTGCCCATTATTGAATTATTT ACATGGTATAATTAGGGCAAGTCTTAACTGGAGTTCACGAACCCCCTGAAATTGTGCACCCATAGCCACCTACACATTCCTTCCAGAGCA CGTGTGCTTTTACCCCAAGATACAAGGAATGTGTAGGCAGCTATGGTTGTCACAGCCTAAGATTTCTGCAACAACAGGGGTTGTATTGGG GGAAGTTTATAATGAATAGGTGTTCTACCATAAAGAGTAATACATCACCTAGACACTTTGGCGGCCTTCCCAGACTCAGGGCCAGTCAGA >In-frame_PAN3_ENST00000399613_chr13_28794515_+_FLT3_ENST00000537084_chr13_28644749_-_3538nt GCCGCAGCCGGCGGAGGAGGCAGTAGCGGGGGACTCGATGGACCGCGGCTGGCAATTCCAGGAATGGATGGAGGTGCTTTAACTGATACA AGTCTCACAGATTCCTATTTTAGCACCAGCTTTATTGGAGTCAATGGATTTGGAAGCCCTGTAGAAACAAAATATCCCCTGATGCAGAGA ATGACTAATAGTAGCAGCTCCCCAAGCCTTCTAAATGACAGTGCCAAGCCATATTCAGCCCATGATCCTCTAACATCACCTGCTTCATCC TTGTTTAATGACTTTGGTGCCCTCAACATCTCTCAGAGACGAAAGACACCAAATCCTACTGCAAGCGAGTTTATTCCTAAAGGAGGATCA ACCTCCAGGCTGAGTAACGTGTCCCAGTCAAATATGTCTGCCTTCTCTCAAGTTTTCTCTCACCCATCCATGGGAAGCCCTGCTACTGCT GGATTAGCGCCAGTTGTTTTTTCTGCAATGATATTTGGGACTATTACAAATCAAGATCTGCCTGTGATCAAGTGTGTTTTAATCAATCAT AAGAACAATGATTCATCAGTGGGGAAGTCATCATCATATCCCATGGTATCAGAATCCCCGGAAGACCTCGGGTGTGCGTTGAGACCCCAG AGCTCAGGGACAGTGTACGAAGCTGCCGCTGTGGAAGTGGATGTATCTGCTTCCATCACACTGCAAGTGCTGGTCGACGCCCCAGGGAAC ATTTCCTGTCTCTGGGTCTTTAAGCACAGCTCCCTGAATTGCCAGCCACATTTTGATTTACAAAACAGAGGAGTTGTTTCCATGGTCATT TTGAAAATGACAGAAACCCAAGCTGGAGAATACCTACTTTTTATTCAGAGTGAAGCTACCAATTACACAATATTGTTTACAGTGAGTATA AGAAATACCCTGCTTTACACATTAAGAAGACCTTACTTTAGAAAAATGGAAAACCAGGACGCCCTGGTCTGCATATCTGAGAGCGTTCCA GAGCCGATCGTGGAATGGGTGCTTTGCGATTCACAGGGGGAAAGCTGTAAAGAAGAAAGTCCAGCTGTTGTTAAAAAGGAGGAAAAAGTG CTTCATGAATTATTTGGGACGGACATAAGGTGCTGTGCCAGAAATGAACTGGGCAGGGAATGCACCAGGCTGTTCACAATAGATCTAAAT CAAACTCCTCAGACCACATTGCCACAATTATTTCTTAAAGTAGGGGAACCCTTATGGATAAGGTGCAAAGCTGTTCATGTGAACCATGGA TTCGGGCTCACCTGGGAATTAGAAAACAAAGCACTCGAGGAGGGCAACTACTTTGAGATGAGTACCTATTCAACAAACAGAACTATGATA CGGATTCTGTTTGCTTTTGTATCATCAGTGGCAAGAAACGACACCGGATACTACACTTGTTCCTCTTCAAAGCATCCCAGTCAATCAGCT TTGGTTACCATCGTAGAAAAGGGATTTATAAATGCTACCAATTCAAGTGAAGATTATGAAATTGACCAATATGAAGAGTTTTGTTTTTCT GTCAGGTTTAAAGCCTACCCACAAATCAGATGTACGTGGACCTTCTCTCGAAAATCATTTCCTTGTGAGCAAAAGGGTCTTGATAACGGA TACAGCATATCCAAGTTTTGCAATCATAAGCACCAGCCAGGAGAATATATATTCCATGCAGAAAATGATGATGCCCAATTTACCAAAATG TTCACGCTGAATATAAGAAGGAAACCTCAAGTGCTCGCAGAAGCATCGGCAAGTCAGGCGTCCTGTTTCTCGGATGGATACCCATTACCA TCTTGGACCTGGAAGAAGTGTTCAGACAAGTCTCCCAACTGCACAGAAGAGATCACAGAAGGAGTCTGGAATAGAAAGGCTAACAGAAAA GTGTTTGGACAGTGGGTGTCGAGCAGTACTCTAAACATGAGTGAAGCCATAAAAGGGTTCCTGGTCAAGTGCTGTGCATACAATTCCCTT GGCACATCTTGTGAGACGATCCTTTTAAACTCTCCAGGCCCCTTCCCTTTCATCCAAGACAACATCTCATTCTATGCAACAATTGGTGTT TGTCTCCTCTTCATTGTCGTTTTAACCCTGCTAATTTGTCACAAGTACAAAAAGCAATTTAGGTATGAAAGCCAGCTACAGATGGTACAG GTGACCGGCTCCTCAGATAATGAGTACTTCTACGTTGATTTCAGAGAATATGAATATGATCTCAAATGGGAGTTTCCAAGAGAAAATTTA GAGTTTGGGAAGGTACTAGGATCAGGTGCTTTTGGAAAAGTGATGAACGCAACAGCTTATGGAATTAGCAAAACAGGAGTCTCAATCCAG GTTGCCGTCAAAATGCTGAAAGAAAAAGCAGACAGCTCTGAAAGAGAGGCACTCATGTCAGAACTCAAGATGATGACCCAGCTGGGAAGC CACGAGAATATTGTGAACCTGCTGGGGGCGTGCACACTGTCAGGACCAATTTACTTGATTTTTGAATACTGTTGCTATGGTGATCTTCTC AACTATCTAAGAAGTAAAAGAGAAAAATTTCACAGGACTTGGACAGAGATTTTCAAGGAACACAATTTCAGTTTTTACCCCACTTTCCAA TCACATCCAAATTCCAGCATGCCTGGTTCAAGAGAAGTTCAGATACACCCGGACTCGGATCAAATCTCAGGGCTTCATGGGAATTCATTT CACTCTGAAGATGAAATTGAATATGAAAACCAAAAAAGGCTGGAAGAAGAGGAGGACTTGAATGTGCTTACATTTGAAGATCTTCTTTGC TTTGCATATCAAGTTGCCAAAGGAATGGAATTTCTGGAATTTAAGTCGGCCCGTCTGCCTGTAAAATGGATGGCCCCCGAAAGCCTGTTT GAAGGCATCTACACCATTAAGAGTGATGTCTGGTCATATGGAATATTACTGTGGGAAATCTTCTCACTTGGTGTGAATCCTTACCCTGGC ATTCCGGTTGATGCTAACTTCTACAAACTGATTCAAAATGGATTTAAAATGGATCAGCCATTTTATGCTACAGAAGAAATATACATTATA ATGCAATCCTGCTGGGCTTTTGACTCAAGGAAACGGCCATCCTTCCCTAATTTGACTTCGTTTTTAGGATGTCAGCTGGCAGATGCAGAA GAAGCGATGTATCAGAATGTGGATGGCCGTGTTTCGGAATGTCCTCACACCTACCAAAACAGGCGACCTTTCAGCAGAGAGATGGATTTG GGGCTACTCTCTCCGCAGGCTCAGGTCGAAGATTCGTAGAGGAACAATTTAGTTTTAAGGACTTCATCCCTCCACCTATCCCTAACAGGC TGTAGATTACCAAAACAAGATTAATTTCATCACTAAAAGAAAATCTATTATCAACTGCTGCTTCACCAGACTTTTCTCTAGAAGCTGTCT GCGTTTACTCTTGTTTTCAAAGGGACTTTTGTAAAATCAAATCATCCTGTCACAAGGCAGGAGGAGCTGATAATGAACTTTATTGGAGCA |
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FusionGenePPI for PAN3_FLT3 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| PAN3 | PAN2, PABPC1, SVIL, ELAVL1, TNRC6C, TNRC6A, TNRC6B, PABPC3, XPO1, ASF1A, ASF1B, KIAA0430, HELZ | FLT3 | SOCS1, GRB2, HSP90AA1, IKBKG, UBE2L6, SIAH1, PIK3R1, SLA, SOCS2, CBL, FLT3, BRCA1, VHL, FBXL13 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for PAN3_FLT3 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Tgene | FLT3 | P36888 | DB09079 | Nintedanib | Receptor-type tyrosine-protein kinase FLT3 | small molecule | approved |
| Tgene | FLT3 | P36888 | DB00398 | Sorafenib | Receptor-type tyrosine-protein kinase FLT3 | small molecule | approved|investigational |
| Tgene | FLT3 | P36888 | DB01268 | Sunitinib | Receptor-type tyrosine-protein kinase FLT3 | small molecule | approved|investigational |
| Tgene | FLT3 | P36888 | DB08901 | Ponatinib | Receptor-type tyrosine-protein kinase FLT3 | small molecule | approved|investigational |
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RelatedDiseases for PAN3_FLT3 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | FLT3 | C0023467 | Leukemia, Myelocytic, Acute | 11 | CTD_human |
| Tgene | FLT3 | C0023487 | Acute Promyelocytic Leukemia | 3 | CTD_human |
| Tgene | FLT3 | C0040053 | Thrombosis | 1 | CTD_human |
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