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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDrugs

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RelatedDiseases

Fusion gene ID: 25870

FusionGeneSummary for PAMR1_SLC1A2

check button Fusion gene summary
Fusion gene informationFusion gene name: PAMR1_SLC1A2
Fusion gene ID: 25870
HgeneTgene
Gene symbol

PAMR1

SLC1A2

Gene ID

25891

6506

Gene namepeptidase domain containing associated with muscle regeneration 1solute carrier family 1 member 2
SynonymsDKFZP586H2123|FP938|RAMPEAAT2|EIEE41|GLT-1|HBGT
Cytomap

11p13

11p13

Type of geneprotein-codingprotein-coding
Descriptioninactive serine protease PAMR1peptidase domain-containing protein associated with muscle regeneration 1regeneration associated muscle proteaseregeneration-associated muscle protease homologexcitatory amino acid transporter 2excitotoxic amino acid transporter 2glutamate/aspartate transporter IIsodium-dependent glutamate/aspartate transporter 2solute carrier family 1 (glial high affinity glutamate transporter), member 2
Modification date2018040320180519
UniProtAcc

Q6UXH9

P43004

Ensembl transtripts involved in fusion geneENST00000278360, ENST00000378880, 
ENST00000378878, ENST00000532848, 
ENST00000534803, 		ENST00000278379, 
ENST00000395750, ENST00000395753, 
ENST00000606205, ENST00000479543, 
Fusion gene scores* DoF score1 X 2 X 1=29 X 8 X 5=360
# samples 211
** MAII scorelog2(2/2*10)=3.32192809488736log2(11/360*10)=-1.71049338280502
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PAMR1 [Title/Abstract] AND SLC1A2 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationTissue-specifically expressed gene involved fusion gene, inframe and retained their domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneSLC1A2

GO:0015813

L-glutamate transmembrane transport

26690923

TgeneSLC1A2

GO:0070207

protein homotrimerization

15265858|15483603

TgeneSLC1A2

GO:0070779

D-aspartate import across plasma membrane

7521911

TgeneSLC1A2

GO:0098712

L-glutamate import across plasma membrane

7521911|15265858|26690923


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDLGGTCGA-FG-8189-01BPAMR1chr11

35453536

-SLC1A2chr11

35339063

-
TCGALDLGGTCGA-HT-7854-01APAMR1chr11

35461175

-SLC1A2chr11

35339063

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
intron-3CDSENST00000278360ENST00000278379PAMR1chr11

35453536

-SLC1A2chr11

35339063

-
intron-5UTRENST00000278360ENST00000395750PAMR1chr11

35453536

-SLC1A2chr11

35339063

-
intron-5UTRENST00000278360ENST00000395753PAMR1chr11

35453536

-SLC1A2chr11

35339063

-
intron-5UTRENST00000278360ENST00000606205PAMR1chr11

35453536

-SLC1A2chr11

35339063

-
intron-intronENST00000278360ENST00000479543PAMR1chr11

35453536

-SLC1A2chr11

35339063

-
intron-3CDSENST00000378880ENST00000278379PAMR1chr11

35453536

-SLC1A2chr11

35339063

-
intron-5UTRENST00000378880ENST00000395750PAMR1chr11

35453536

-SLC1A2chr11

35339063

-
intron-5UTRENST00000378880ENST00000395753PAMR1chr11

35453536

-SLC1A2chr11

35339063

-
intron-5UTRENST00000378880ENST00000606205PAMR1chr11

35453536

-SLC1A2chr11

35339063

-
intron-intronENST00000378880ENST00000479543PAMR1chr11

35453536

-SLC1A2chr11

35339063

-
intron-3CDSENST00000378878ENST00000278379PAMR1chr11

35453536

-SLC1A2chr11

35339063

-
intron-5UTRENST00000378878ENST00000395750PAMR1chr11

35453536

-SLC1A2chr11

35339063

-
intron-5UTRENST00000378878ENST00000395753PAMR1chr11

35453536

-SLC1A2chr11

35339063

-
intron-5UTRENST00000378878ENST00000606205PAMR1chr11

35453536

-SLC1A2chr11

35339063

-
intron-intronENST00000378878ENST00000479543PAMR1chr11

35453536

-SLC1A2chr11

35339063

-
intron-3CDSENST00000532848ENST00000278379PAMR1chr11

35453536

-SLC1A2chr11

35339063

-
intron-5UTRENST00000532848ENST00000395750PAMR1chr11

35453536

-SLC1A2chr11

35339063

-
intron-5UTRENST00000532848ENST00000395753PAMR1chr11

35453536

-SLC1A2chr11

35339063

-
intron-5UTRENST00000532848ENST00000606205PAMR1chr11

35453536

-SLC1A2chr11

35339063

-
intron-intronENST00000532848ENST00000479543PAMR1chr11

35453536

-SLC1A2chr11

35339063

-
intron-3CDSENST00000534803ENST00000278379PAMR1chr11

35453536

-SLC1A2chr11

35339063

-
intron-5UTRENST00000534803ENST00000395750PAMR1chr11

35453536

-SLC1A2chr11

35339063

-
intron-5UTRENST00000534803ENST00000395753PAMR1chr11

35453536

-SLC1A2chr11

35339063

-
intron-5UTRENST00000534803ENST00000606205PAMR1chr11

35453536

-SLC1A2chr11

35339063

-
intron-intronENST00000534803ENST00000479543PAMR1chr11

35453536

-SLC1A2chr11

35339063

-
In-frameENST00000278360ENST00000278379PAMR1chr11

35461175

-SLC1A2chr11

35339063

-
5CDS-5UTRENST00000278360ENST00000395750PAMR1chr11

35461175

-SLC1A2chr11

35339063

-
5CDS-5UTRENST00000278360ENST00000395753PAMR1chr11

35461175

-SLC1A2chr11

35339063

-
5CDS-5UTRENST00000278360ENST00000606205PAMR1chr11

35461175

-SLC1A2chr11

35339063

-
5CDS-intronENST00000278360ENST00000479543PAMR1chr11

35461175

-SLC1A2chr11

35339063

-
In-frameENST00000378880ENST00000278379PAMR1chr11

35461175

-SLC1A2chr11

35339063

-
5CDS-5UTRENST00000378880ENST00000395750PAMR1chr11

35461175

-SLC1A2chr11

35339063

-
5CDS-5UTRENST00000378880ENST00000395753PAMR1chr11

35461175

-SLC1A2chr11

35339063

-
5CDS-5UTRENST00000378880ENST00000606205PAMR1chr11

35461175

-SLC1A2chr11

35339063

-
5CDS-intronENST00000378880ENST00000479543PAMR1chr11

35461175

-SLC1A2chr11

35339063

-
In-frameENST00000378878ENST00000278379PAMR1chr11

35461175

-SLC1A2chr11

35339063

-
5CDS-5UTRENST00000378878ENST00000395750PAMR1chr11

35461175

-SLC1A2chr11

35339063

-
5CDS-5UTRENST00000378878ENST00000395753PAMR1chr11

35461175

-SLC1A2chr11

35339063

-
5CDS-5UTRENST00000378878ENST00000606205PAMR1chr11

35461175

-SLC1A2chr11

35339063

-
5CDS-intronENST00000378878ENST00000479543PAMR1chr11

35461175

-SLC1A2chr11

35339063

-
Frame-shiftENST00000532848ENST00000278379PAMR1chr11

35461175

-SLC1A2chr11

35339063

-
5CDS-5UTRENST00000532848ENST00000395750PAMR1chr11

35461175

-SLC1A2chr11

35339063

-
5CDS-5UTRENST00000532848ENST00000395753PAMR1chr11

35461175

-SLC1A2chr11

35339063

-
5CDS-5UTRENST00000532848ENST00000606205PAMR1chr11

35461175

-SLC1A2chr11

35339063

-
5CDS-intronENST00000532848ENST00000479543PAMR1chr11

35461175

-SLC1A2chr11

35339063

-
intron-3CDSENST00000534803ENST00000278379PAMR1chr11

35461175

-SLC1A2chr11

35339063

-
intron-5UTRENST00000534803ENST00000395750PAMR1chr11

35461175

-SLC1A2chr11

35339063

-
intron-5UTRENST00000534803ENST00000395753PAMR1chr11

35461175

-SLC1A2chr11

35339063

-
intron-5UTRENST00000534803ENST00000606205PAMR1chr11

35461175

-SLC1A2chr11

35339063

-
intron-intronENST00000534803ENST00000479543PAMR1chr11

35461175

-SLC1A2chr11

35339063

-

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FusionProtFeatures for PAMR1_SLC1A2


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
PAMR1

Q6UXH9

SLC1A2

P43004

Sodium-dependent, high-affinity amino acid transporterthat mediates the uptake of L-glutamate and also L-aspartate andD-aspartate (PubMed:7521911, PubMed:14506254, PubMed:15265858,PubMed:26690923). Functions as a symporter that transports oneamino acid molecule together with two or three Na(+) ions and oneproton, in parallel with the counter-transport of one K(+) ion(PubMed:14506254). Mediates Cl(-) flux that is not coupled toamino acid transport; this avoids the accumulation of negativecharges due to aspartate and Na(+) symport (PubMed:14506254).Essential for the rapid removal of released glutamate from thesynaptic cleft, and for terminating the postsynaptic action ofglutamate (By similarity). {ECO:0000250|UniProtKB:P43006,ECO:0000269|PubMed:15265858, ECO:0000269|PubMed:26690923,ECO:0000269|PubMed:7521911}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePAMR1chr11:35461175chr11:35339063ENST00000278360-91242_94383738Compositional biasNote=Cys-rich
HgenePAMR1chr11:35461175chr11:35339063ENST00000378880-81142_94366721Compositional biasNote=Cys-rich
HgenePAMR1chr11:35461175chr11:35339063ENST00000278360-912128_236383738DomainCUB
HgenePAMR1chr11:35461175chr11:35339063ENST00000278360-912235_272383738DomainEGF-like
HgenePAMR1chr11:35461175chr11:35339063ENST00000278360-912278_344383738DomainSushi 1
HgenePAMR1chr11:35461175chr11:35339063ENST00000378880-811128_236366721DomainCUB
HgenePAMR1chr11:35461175chr11:35339063ENST00000378880-811235_272366721DomainEGF-like
HgenePAMR1chr11:35461175chr11:35339063ENST00000378880-811278_344366721DomainSushi 1
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000278379-011345_3755575IntramembraneDiscontinuously helical
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000278379-011425_4585575IntramembraneDiscontinuously helical
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395750-112345_375-4566IntramembraneDiscontinuously helical
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395750-112425_458-4566IntramembraneDiscontinuously helical
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395753-112345_375-4566IntramembraneDiscontinuously helical
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395753-112425_458-4566IntramembraneDiscontinuously helical
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000278379-011362_3645575RegionAspartate binding
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000278379-011442_4465575RegionAspartate binding
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395750-112362_364-4566RegionAspartate binding
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395750-112442_446-4566RegionAspartate binding
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395753-112362_364-4566RegionAspartate binding
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395753-112442_446-4566RegionAspartate binding
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000278379-011109_1205575Topological domainCytoplasmic
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000278379-011143_2355575Topological domainExtracellular
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000278379-011260_2685575Topological domainCytoplasmic
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000278379-011297_3175575Topological domainExtracellular
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000278379-011340_3445575Topological domainCytoplasmic
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000278379-011376_3845575Topological domainCytoplasmic
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000278379-011412_4245575Topological domainExtracellular
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000278379-011459_4715575Topological domainExtracellular
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000278379-011494_5745575Topological domainCytoplasmic
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000278379-01165_875575Topological domainExtracellular
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395750-112109_120-4566Topological domainCytoplasmic
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395750-112143_235-4566Topological domainExtracellular
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395750-1121_44-4566Topological domainCytoplasmic
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395750-112260_268-4566Topological domainCytoplasmic
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395750-112297_317-4566Topological domainExtracellular
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395750-112340_344-4566Topological domainCytoplasmic
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395750-112376_384-4566Topological domainCytoplasmic
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395750-112412_424-4566Topological domainExtracellular
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395750-112459_471-4566Topological domainExtracellular
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395750-112494_574-4566Topological domainCytoplasmic
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395750-11265_87-4566Topological domainExtracellular
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395753-112109_120-4566Topological domainCytoplasmic
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395753-112143_235-4566Topological domainExtracellular
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395753-1121_44-4566Topological domainCytoplasmic
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395753-112260_268-4566Topological domainCytoplasmic
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395753-112297_317-4566Topological domainExtracellular
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395753-112340_344-4566Topological domainCytoplasmic
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395753-112376_384-4566Topological domainCytoplasmic
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395753-112412_424-4566Topological domainExtracellular
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395753-112459_471-4566Topological domainExtracellular
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395753-112494_574-4566Topological domainCytoplasmic
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395753-11265_87-4566Topological domainExtracellular
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000278379-011121_1425575TransmembraneHelical
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000278379-011236_2595575TransmembraneHelical%3B Name%3D4
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000278379-011269_2965575TransmembraneHelical%3B Name%3D5
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000278379-011318_3395575TransmembraneHelical%3B Name%3D6
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000278379-011385_4115575TransmembraneHelical%3B Name%3D7
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000278379-01145_645575TransmembraneHelical
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000278379-011472_4935575TransmembraneHelical%3B Name%3D8
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000278379-01188_1085575TransmembraneHelical
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395750-112121_142-4566TransmembraneHelical
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395750-112236_259-4566TransmembraneHelical%3B Name%3D4
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395750-112269_296-4566TransmembraneHelical%3B Name%3D5
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395750-112318_339-4566TransmembraneHelical%3B Name%3D6
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395750-112385_411-4566TransmembraneHelical%3B Name%3D7
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395750-11245_64-4566TransmembraneHelical
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395750-112472_493-4566TransmembraneHelical%3B Name%3D8
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395750-11288_108-4566TransmembraneHelical
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395753-112121_142-4566TransmembraneHelical
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395753-112236_259-4566TransmembraneHelical%3B Name%3D4
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395753-112269_296-4566TransmembraneHelical%3B Name%3D5
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395753-112318_339-4566TransmembraneHelical%3B Name%3D6
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395753-112385_411-4566TransmembraneHelical%3B Name%3D7
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395753-11245_64-4566TransmembraneHelical
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395753-112472_493-4566TransmembraneHelical%3B Name%3D8
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000395753-11288_108-4566TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePAMR1chr11:35461175chr11:35339063ENST00000278360-912387_444383738DomainSushi 2
HgenePAMR1chr11:35461175chr11:35339063ENST00000278360-912445_720383738DomainPeptidase S1
HgenePAMR1chr11:35461175chr11:35339063ENST00000378880-811387_444366721DomainSushi 2
HgenePAMR1chr11:35461175chr11:35339063ENST00000378880-811445_720366721DomainPeptidase S1
TgeneSLC1A2chr11:35461175chr11:35339063ENST00000278379-0111_445575Topological domainCytoplasmic


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FusionGeneSequence for PAMR1_SLC1A2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_PAMR1_ENST00000278360_chr11_35461175_-_SLC1A2_ENST00000278379_chr11_35339063_-_953aa
MELGCWTQLGLTFLQLLLISSLPREYTVINEACPGAEWNIMCRECCEYDQIECVCPGKREVVGYTIPCCRNEENECDSCLIHPGCTIFEN
CKSCRNGSWGGTLDDFYVKGFYCAECRAGWYGGDCMRCGQVLRAPKGQILLESYPLNAHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYD
YVEVRDGDNRDGQIIKRVCGNERPAPIQSIGSSLHVLFHSDGSKNFDGFHAIYEEITACSSSPCFHDGTCVLDKAGSYKCACLAGYTGQR
CENLLEAGKSKIKASEDSLSVLEERNCSDPGGPVNGYQKITGGPGLINGRHAKIGTVVSFFCNNSYVLSGNEKRTCQQNGEWSGKQPICI
KACREPKISDLVRRRVLPMQVQSSANNMPKQVEVRMHDSHLGSEEPKHRHLGLRLCDKLGKNLLLTLTVFGVILGAVCGGLLRLASPIHP
DVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGPGKKNDEV
SSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVAPPPDEEANATSAVVSLLNETVTEVPEETKMVIKKGLEFKDGMNVLGLIGFFIAF
GIAMGKMGDQAKLMVDFFNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMVTVIIGLIIHGGIFLPLIYFVVTRK
NPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVLDGGQIVTVSLTA
TLASVGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSKSELDTIDSQHRVHEDIEMTKTQSI

>In-frame_PAMR1_ENST00000378880_chr11_35461175_-_SLC1A2_ENST00000278379_chr11_35339063_-_936aa
MELGCWTQLGLTFLQLLLISSLPREYTVINEACPGAEWNIMCRECCEYDQIECVCPGKREVVGYTIPCCRNEENECDSCLIHPGCTIFEN
CKSCRNGSWGGTLDDFYVKGFYCAECRAGWYGGDCMRCGQVLRAPKGQILLESYPLNAHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYD
YVEVRDGDNRDGQIIKRVCGNERPAPIQSIGSSLHVLFHSDGSKNFDGFHAIYEEITACSSSPCFHDGTCVLDKAGSYKCACLAGYTGQR
CENLLEERNCSDPGGPVNGYQKITGGPGLINGRHAKIGTVVSFFCNNSYVLSGNEKRTCQQNGEWSGKQPICIKACREPKISDLVRRRVL
PMQVQSSANNMPKQVEVRMHDSHLGSEEPKHRHLGLRLCDKLGKNLLLTLTVFGVILGAVCGGLLRLASPIHPDVVMLIAFPGDILMRML
KMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGPGKKNDEVSSLDAFLDLIRNLFPEN
LVQACFQQIQTVTKKVLVAPPPDEEANATSAVVSLLNETVTEVPEETKMVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGDQAKLMVDF
FNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLEVVARQLGMYMVTVIIGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITAL
GTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVLDGGQIVTVSLTATLASVGAASIPSAGLVT
MLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDSFGAGIVYHLSKSELDTIDSQHRVHEDIEMTKTQSIYDDMKNHRESNSNQCVY

>In-frame_PAMR1_ENST00000378878_chr11_35461175_-_SLC1A2_ENST00000278379_chr11_35339063_-_825aa
MELGCWTQLGLTFLQLLLISSLPREYTVINEACPGAEWNIMCRECCEYDQIECVCPGKREVVGYTIPCCRNEENECDSCLIHPGCTIFEN
CKSCRNGSWGGTLDDFYVKGFYCAECRAGWYGGDCMPCSSSPCFHDGTCVLDKAGSYKCACLAGYTGQRCENLLEERNCSDPGGPVNGYQ
KITGGPGLINGRHAKIGTVVSFFCNNSYVLSGNEKRTCQQNGEWSGKQPICIKACREPKISDLVRRRVLPMQVQSSANNMPKQVEVRMHD
SHLGSEEPKHRHLGLRLCDKLGKNLLLTLTVFGVILGAVCGGLLRLASPIHPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDA
KASGRLGTRAMVYYMSTTIIAAVLGVILVLAIHPGNPKLKKQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQTVTKKVLVAPP
PDEEANATSAVVSLLNETVTEVPEETKMVIKKGLEFKDGMNVLGLIGFFIAFGIAMGKMGDQAKLMVDFFNILNEIVMKLVIMIMWYSPL
GIACLICGKIIAIKDLEVVARQLGMYMVTVIIGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTASSAGTLPVTFRCLEENLG
IDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVLDGGQIVTVSLTATLASVGAASIPSAGLVTMLLILTAVGLPTEDISLLVAV
DWLLDRMRTSVNVVGDSFGAGIVYHLSKSELDTIDSQHRVHEDIEMTKTQSIYDDMKNHRESNSNQCVYAAHNSVIVDECKVTLAANGKS


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_PAMR1_ENST00000278360_chr11_35461175_-_SLC1A2_ENST00000278379_chr11_35339063_-_2859nt
ATGGAGCTGGGTTGCTGGACGCAGTTGGGGCTCACTTTTCTTCAGCTCCTTCTCATCTCGTCCTTGCCAAGAGAGTACACAGTCATTAAT
GAAGCCTGCCCTGGAGCAGAGTGGAATATCATGTGTCGGGAGTGCTGTGAATATGATCAGATTGAGTGCGTCTGCCCCGGAAAGAGGGAA
GTCGTGGGTTATACCATCCCTTGCTGCAGGAATGAGGAGAATGAGTGTGACTCCTGCCTGATCCACCCAGGTTGTACCATCTTTGAAAAC
TGCAAGAGCTGCCGAAATGGCTCATGGGGGGGTACCTTGGATGACTTCTATGTGAAGGGGTTCTACTGTGCAGAGTGCCGAGCAGGCTGG
TACGGAGGAGACTGCATGCGATGTGGCCAGGTTCTGCGAGCCCCAAAGGGTCAGATTTTGTTGGAAAGCTATCCCCTAAATGCTCACTGT
GAATGGACCATTCATGCTAAACCTGGGTTTGTCATCCAACTAAGATTTGTCATGTTGAGCCTGGAGTTTGACTACATGTGCCAGTATGAC
TATGTTGAGGTTCGTGATGGAGACAACCGCGATGGCCAGATCATCAAGCGTGTCTGTGGCAACGAGCGGCCAGCTCCTATCCAGAGCATA
GGATCCTCACTCCACGTCCTCTTCCACTCCGATGGCTCCAAGAATTTTGACGGTTTCCATGCCATTTATGAGGAGATCACAGCATGCTCC
TCATCCCCTTGTTTCCATGACGGCACGTGCGTCCTTGACAAGGCTGGATCTTACAAGTGTGCCTGCTTGGCAGGCTATACTGGGCAGCGC
TGTGAAAATCTTCTGGAGGCTGGGAAGTCCAAGATCAAGGCGTCAGAAGATTCATTGTCTGTCCTTGAAGAAAGAAACTGCTCAGACCCT
GGGGGCCCAGTCAATGGGTACCAGAAAATAACAGGGGGCCCTGGGCTTATCAACGGACGCCATGCTAAAATTGGCACCGTGGTGTCTTTC
TTTTGTAACAACTCCTATGTTCTTAGTGGCAATGAGAAAAGAACTTGCCAGCAGAATGGAGAGTGGTCAGGGAAACAGCCCATCTGCATA
AAAGCCTGCCGAGAACCAAAGATTTCAGACCTGGTGAGAAGGAGAGTTCTTCCGATGCAGGTTCAGTCAAGTGCCAACAATATGCCCAAG
CAGGTGGAAGTGCGAATGCACGACAGTCATCTTGGCTCAGAGGAACCCAAGCACCGGCACCTGGGCCTGCGCCTGTGTGACAAGCTGGGG
AAGAATCTGCTGCTCACCCTGACGGTGTTTGGTGTCATCCTGGGAGCAGTGTGTGGAGGGCTTCTTCGCTTGGCATCTCCCATCCACCCT
GATGTGGTTATGTTAATAGCCTTCCCAGGGGATATACTCATGAGGATGCTAAAAATGCTCATTCTCCCTCTAATCATCTCCAGCTTAATC
ACAGGGTTGTCAGGCCTGGATGCTAAGGCTAGTGGCCGCTTGGGCACGAGAGCCATGGTGTATTACATGTCCACGACCATCATTGCTGCA
GTACTGGGGGTCATTCTGGTCTTGGCTATCCATCCAGGCAATCCCAAGCTCAAGAAGCAGCTGGGGCCTGGGAAGAAGAATGATGAAGTG
TCCAGCCTGGATGCCTTCCTGGACCTTATTCGAAATCTCTTCCCTGAAAACCTTGTCCAAGCCTGCTTTCAACAGATTCAAACAGTGACG
AAGAAAGTCCTGGTTGCACCACCGCCGGACGAGGAGGCCAACGCAACCAGCGCTGTTGTCTCTCTGTTGAACGAGACTGTGACTGAGGTG
CCGGAGGAGACTAAGATGGTTATCAAGAAGGGCCTGGAGTTCAAGGATGGGATGAACGTCTTAGGTCTGATAGGGTTTTTCATTGCTTTT
GGCATCGCTATGGGGAAGATGGGAGATCAGGCCAAGCTGATGGTGGATTTCTTCAACATTTTGAATGAGATTGTAATGAAGTTAGTGATC
ATGATCATGTGGTACTCTCCCCTGGGTATCGCCTGCCTGATCTGTGGAAAGATCATTGCAATCAAGGACTTAGAAGTGGTTGCTAGGCAA
CTGGGGATGTACATGGTAACAGTGATCATAGGCCTCATCATCCACGGGGGCATCTTTCTCCCCTTGATTTACTTTGTAGTGACCAGGAAA
AACCCCTTCTCCTTTTTTGCTGGCATTTTCCAAGCTTGGATCACTGCCCTGGGCACCGCTTCCAGTGCTGGAACTTTGCCTGTCACCTTT
CGTTGCCTGGAAGAAAATCTGGGGATTGATAAGCGTGTGACTAGATTCGTCCTTCCTGTTGGAGCAACCATTAACATGGATGGTACAGCC
CTTTATGAAGCGGTAGCCGCCATCTTTATAGCCCAAATGAATGGTGTTGTCCTGGATGGAGGACAGATTGTGACTGTAAGCCTCACAGCC
ACCCTGGCAAGCGTCGGCGCGGCCAGTATCCCCAGTGCCGGGCTGGTCACCATGCTCCTCATTCTGACAGCCGTGGGCCTGCCAACAGAG
GACATCAGCCTGCTGGTGGCTGTGGACTGGCTGCTGGACAGGATGAGAACTTCAGTCAATGTTGTGGGTGACTCTTTTGGGGCTGGGATA
GTCTATCACCTCTCCAAGTCTGAGCTGGATACCATTGACTCCCAGCATCGAGTGCATGAAGATATTGAAATGACCAAGACTCAATCCATT
TATGATGACATGAAGAACCACAGGGAAAGCAACTCTAATCAATGTGTCTATGCTGCACACAACTCTGTCATAGTAGATGAATGCAAGGTA

>In-frame_PAMR1_ENST00000378880_chr11_35461175_-_SLC1A2_ENST00000278379_chr11_35339063_-_2808nt
ATGGAGCTGGGTTGCTGGACGCAGTTGGGGCTCACTTTTCTTCAGCTCCTTCTCATCTCGTCCTTGCCAAGAGAGTACACAGTCATTAAT
GAAGCCTGCCCTGGAGCAGAGTGGAATATCATGTGTCGGGAGTGCTGTGAATATGATCAGATTGAGTGCGTCTGCCCCGGAAAGAGGGAA
GTCGTGGGTTATACCATCCCTTGCTGCAGGAATGAGGAGAATGAGTGTGACTCCTGCCTGATCCACCCAGGTTGTACCATCTTTGAAAAC
TGCAAGAGCTGCCGAAATGGCTCATGGGGGGGTACCTTGGATGACTTCTATGTGAAGGGGTTCTACTGTGCAGAGTGCCGAGCAGGCTGG
TACGGAGGAGACTGCATGCGATGTGGCCAGGTTCTGCGAGCCCCAAAGGGTCAGATTTTGTTGGAAAGCTATCCCCTAAATGCTCACTGT
GAATGGACCATTCATGCTAAACCTGGGTTTGTCATCCAACTAAGATTTGTCATGTTGAGCCTGGAGTTTGACTACATGTGCCAGTATGAC
TATGTTGAGGTTCGTGATGGAGACAACCGCGATGGCCAGATCATCAAGCGTGTCTGTGGCAACGAGCGGCCAGCTCCTATCCAGAGCATA
GGATCCTCACTCCACGTCCTCTTCCACTCCGATGGCTCCAAGAATTTTGACGGTTTCCATGCCATTTATGAGGAGATCACAGCATGCTCC
TCATCCCCTTGTTTCCATGACGGCACGTGCGTCCTTGACAAGGCTGGATCTTACAAGTGTGCCTGCTTGGCAGGCTATACTGGGCAGCGC
TGTGAAAATCTCCTTGAAGAAAGAAACTGCTCAGACCCTGGGGGCCCAGTCAATGGGTACCAGAAAATAACAGGGGGCCCTGGGCTTATC
AACGGACGCCATGCTAAAATTGGCACCGTGGTGTCTTTCTTTTGTAACAACTCCTATGTTCTTAGTGGCAATGAGAAAAGAACTTGCCAG
CAGAATGGAGAGTGGTCAGGGAAACAGCCCATCTGCATAAAAGCCTGCCGAGAACCAAAGATTTCAGACCTGGTGAGAAGGAGAGTTCTT
CCGATGCAGGTTCAGTCAAGTGCCAACAATATGCCCAAGCAGGTGGAAGTGCGAATGCACGACAGTCATCTTGGCTCAGAGGAACCCAAG
CACCGGCACCTGGGCCTGCGCCTGTGTGACAAGCTGGGGAAGAATCTGCTGCTCACCCTGACGGTGTTTGGTGTCATCCTGGGAGCAGTG
TGTGGAGGGCTTCTTCGCTTGGCATCTCCCATCCACCCTGATGTGGTTATGTTAATAGCCTTCCCAGGGGATATACTCATGAGGATGCTA
AAAATGCTCATTCTCCCTCTAATCATCTCCAGCTTAATCACAGGGTTGTCAGGCCTGGATGCTAAGGCTAGTGGCCGCTTGGGCACGAGA
GCCATGGTGTATTACATGTCCACGACCATCATTGCTGCAGTACTGGGGGTCATTCTGGTCTTGGCTATCCATCCAGGCAATCCCAAGCTC
AAGAAGCAGCTGGGGCCTGGGAAGAAGAATGATGAAGTGTCCAGCCTGGATGCCTTCCTGGACCTTATTCGAAATCTCTTCCCTGAAAAC
CTTGTCCAAGCCTGCTTTCAACAGATTCAAACAGTGACGAAGAAAGTCCTGGTTGCACCACCGCCGGACGAGGAGGCCAACGCAACCAGC
GCTGTTGTCTCTCTGTTGAACGAGACTGTGACTGAGGTGCCGGAGGAGACTAAGATGGTTATCAAGAAGGGCCTGGAGTTCAAGGATGGG
ATGAACGTCTTAGGTCTGATAGGGTTTTTCATTGCTTTTGGCATCGCTATGGGGAAGATGGGAGATCAGGCCAAGCTGATGGTGGATTTC
TTCAACATTTTGAATGAGATTGTAATGAAGTTAGTGATCATGATCATGTGGTACTCTCCCCTGGGTATCGCCTGCCTGATCTGTGGAAAG
ATCATTGCAATCAAGGACTTAGAAGTGGTTGCTAGGCAACTGGGGATGTACATGGTAACAGTGATCATAGGCCTCATCATCCACGGGGGC
ATCTTTCTCCCCTTGATTTACTTTGTAGTGACCAGGAAAAACCCCTTCTCCTTTTTTGCTGGCATTTTCCAAGCTTGGATCACTGCCCTG
GGCACCGCTTCCAGTGCTGGAACTTTGCCTGTCACCTTTCGTTGCCTGGAAGAAAATCTGGGGATTGATAAGCGTGTGACTAGATTCGTC
CTTCCTGTTGGAGCAACCATTAACATGGATGGTACAGCCCTTTATGAAGCGGTAGCCGCCATCTTTATAGCCCAAATGAATGGTGTTGTC
CTGGATGGAGGACAGATTGTGACTGTAAGCCTCACAGCCACCCTGGCAAGCGTCGGCGCGGCCAGTATCCCCAGTGCCGGGCTGGTCACC
ATGCTCCTCATTCTGACAGCCGTGGGCCTGCCAACAGAGGACATCAGCCTGCTGGTGGCTGTGGACTGGCTGCTGGACAGGATGAGAACT
TCAGTCAATGTTGTGGGTGACTCTTTTGGGGCTGGGATAGTCTATCACCTCTCCAAGTCTGAGCTGGATACCATTGACTCCCAGCATCGA
GTGCATGAAGATATTGAAATGACCAAGACTCAATCCATTTATGATGACATGAAGAACCACAGGGAAAGCAACTCTAATCAATGTGTCTAT
GCTGCACACAACTCTGTCATAGTAGATGAATGCAAGGTAACTCTGGCAGCCAATGGAAAGTCAGCCGACTGCAGTGTTGAGGAAGAACCT

>In-frame_PAMR1_ENST00000378878_chr11_35461175_-_SLC1A2_ENST00000278379_chr11_35339063_-_2475nt
ATGGAGCTGGGTTGCTGGACGCAGTTGGGGCTCACTTTTCTTCAGCTCCTTCTCATCTCGTCCTTGCCAAGAGAGTACACAGTCATTAAT
GAAGCCTGCCCTGGAGCAGAGTGGAATATCATGTGTCGGGAGTGCTGTGAATATGATCAGATTGAGTGCGTCTGCCCCGGAAAGAGGGAA
GTCGTGGGTTATACCATCCCTTGCTGCAGGAATGAGGAGAATGAGTGTGACTCCTGCCTGATCCACCCAGGTTGTACCATCTTTGAAAAC
TGCAAGAGCTGCCGAAATGGCTCATGGGGGGGTACCTTGGATGACTTCTATGTGAAGGGGTTCTACTGTGCAGAGTGCCGAGCAGGCTGG
TACGGAGGAGACTGCATGCCATGCTCCTCATCCCCTTGTTTCCATGACGGCACGTGCGTCCTTGACAAGGCTGGATCTTACAAGTGTGCC
TGCTTGGCAGGCTATACTGGGCAGCGCTGTGAAAATCTCCTTGAAGAAAGAAACTGCTCAGACCCTGGGGGCCCAGTCAATGGGTACCAG
AAAATAACAGGGGGCCCTGGGCTTATCAACGGACGCCATGCTAAAATTGGCACCGTGGTGTCTTTCTTTTGTAACAACTCCTATGTTCTT
AGTGGCAATGAGAAAAGAACTTGCCAGCAGAATGGAGAGTGGTCAGGGAAACAGCCCATCTGCATAAAAGCCTGCCGAGAACCAAAGATT
TCAGACCTGGTGAGAAGGAGAGTTCTTCCGATGCAGGTTCAGTCAAGTGCCAACAATATGCCCAAGCAGGTGGAAGTGCGAATGCACGAC
AGTCATCTTGGCTCAGAGGAACCCAAGCACCGGCACCTGGGCCTGCGCCTGTGTGACAAGCTGGGGAAGAATCTGCTGCTCACCCTGACG
GTGTTTGGTGTCATCCTGGGAGCAGTGTGTGGAGGGCTTCTTCGCTTGGCATCTCCCATCCACCCTGATGTGGTTATGTTAATAGCCTTC
CCAGGGGATATACTCATGAGGATGCTAAAAATGCTCATTCTCCCTCTAATCATCTCCAGCTTAATCACAGGGTTGTCAGGCCTGGATGCT
AAGGCTAGTGGCCGCTTGGGCACGAGAGCCATGGTGTATTACATGTCCACGACCATCATTGCTGCAGTACTGGGGGTCATTCTGGTCTTG
GCTATCCATCCAGGCAATCCCAAGCTCAAGAAGCAGCTGGGGCCTGGGAAGAAGAATGATGAAGTGTCCAGCCTGGATGCCTTCCTGGAC
CTTATTCGAAATCTCTTCCCTGAAAACCTTGTCCAAGCCTGCTTTCAACAGATTCAAACAGTGACGAAGAAAGTCCTGGTTGCACCACCG
CCGGACGAGGAGGCCAACGCAACCAGCGCTGTTGTCTCTCTGTTGAACGAGACTGTGACTGAGGTGCCGGAGGAGACTAAGATGGTTATC
AAGAAGGGCCTGGAGTTCAAGGATGGGATGAACGTCTTAGGTCTGATAGGGTTTTTCATTGCTTTTGGCATCGCTATGGGGAAGATGGGA
GATCAGGCCAAGCTGATGGTGGATTTCTTCAACATTTTGAATGAGATTGTAATGAAGTTAGTGATCATGATCATGTGGTACTCTCCCCTG
GGTATCGCCTGCCTGATCTGTGGAAAGATCATTGCAATCAAGGACTTAGAAGTGGTTGCTAGGCAACTGGGGATGTACATGGTAACAGTG
ATCATAGGCCTCATCATCCACGGGGGCATCTTTCTCCCCTTGATTTACTTTGTAGTGACCAGGAAAAACCCCTTCTCCTTTTTTGCTGGC
ATTTTCCAAGCTTGGATCACTGCCCTGGGCACCGCTTCCAGTGCTGGAACTTTGCCTGTCACCTTTCGTTGCCTGGAAGAAAATCTGGGG
ATTGATAAGCGTGTGACTAGATTCGTCCTTCCTGTTGGAGCAACCATTAACATGGATGGTACAGCCCTTTATGAAGCGGTAGCCGCCATC
TTTATAGCCCAAATGAATGGTGTTGTCCTGGATGGAGGACAGATTGTGACTGTAAGCCTCACAGCCACCCTGGCAAGCGTCGGCGCGGCC
AGTATCCCCAGTGCCGGGCTGGTCACCATGCTCCTCATTCTGACAGCCGTGGGCCTGCCAACAGAGGACATCAGCCTGCTGGTGGCTGTG
GACTGGCTGCTGGACAGGATGAGAACTTCAGTCAATGTTGTGGGTGACTCTTTTGGGGCTGGGATAGTCTATCACCTCTCCAAGTCTGAG
CTGGATACCATTGACTCCCAGCATCGAGTGCATGAAGATATTGAAATGACCAAGACTCAATCCATTTATGATGACATGAAGAACCACAGG
GAAAGCAACTCTAATCAATGTGTCTATGCTGCACACAACTCTGTCATAGTAGATGAATGCAAGGTAACTCTGGCAGCCAATGGAAAGTCA


* Fusion transcript sequences (Full-length transcript).
>In-frame_PAMR1_ENST00000278360_chr11_35461175_-_SLC1A2_ENST00000278379_chr11_35339063_-_12585nt
CCTCCCCAGTAGACGCTCGGGCACCAGCCGCGGCAAGGATGGAGCTGGGTTGCTGGACGCAGTTGGGGCTCACTTTTCTTCAGCTCCTTC
TCATCTCGTCCTTGCCAAGAGAGTACACAGTCATTAATGAAGCCTGCCCTGGAGCAGAGTGGAATATCATGTGTCGGGAGTGCTGTGAAT
ATGATCAGATTGAGTGCGTCTGCCCCGGAAAGAGGGAAGTCGTGGGTTATACCATCCCTTGCTGCAGGAATGAGGAGAATGAGTGTGACT
CCTGCCTGATCCACCCAGGTTGTACCATCTTTGAAAACTGCAAGAGCTGCCGAAATGGCTCATGGGGGGGTACCTTGGATGACTTCTATG
TGAAGGGGTTCTACTGTGCAGAGTGCCGAGCAGGCTGGTACGGAGGAGACTGCATGCGATGTGGCCAGGTTCTGCGAGCCCCAAAGGGTC
AGATTTTGTTGGAAAGCTATCCCCTAAATGCTCACTGTGAATGGACCATTCATGCTAAACCTGGGTTTGTCATCCAACTAAGATTTGTCA
TGTTGAGCCTGGAGTTTGACTACATGTGCCAGTATGACTATGTTGAGGTTCGTGATGGAGACAACCGCGATGGCCAGATCATCAAGCGTG
TCTGTGGCAACGAGCGGCCAGCTCCTATCCAGAGCATAGGATCCTCACTCCACGTCCTCTTCCACTCCGATGGCTCCAAGAATTTTGACG
GTTTCCATGCCATTTATGAGGAGATCACAGCATGCTCCTCATCCCCTTGTTTCCATGACGGCACGTGCGTCCTTGACAAGGCTGGATCTT
ACAAGTGTGCCTGCTTGGCAGGCTATACTGGGCAGCGCTGTGAAAATCTTCTGGAGGCTGGGAAGTCCAAGATCAAGGCGTCAGAAGATT
CATTGTCTGTCCTTGAAGAAAGAAACTGCTCAGACCCTGGGGGCCCAGTCAATGGGTACCAGAAAATAACAGGGGGCCCTGGGCTTATCA
ACGGACGCCATGCTAAAATTGGCACCGTGGTGTCTTTCTTTTGTAACAACTCCTATGTTCTTAGTGGCAATGAGAAAAGAACTTGCCAGC
AGAATGGAGAGTGGTCAGGGAAACAGCCCATCTGCATAAAAGCCTGCCGAGAACCAAAGATTTCAGACCTGGTGAGAAGGAGAGTTCTTC
CGATGCAGGTTCAGTCAAGTGCCAACAATATGCCCAAGCAGGTGGAAGTGCGAATGCACGACAGTCATCTTGGCTCAGAGGAACCCAAGC
ACCGGCACCTGGGCCTGCGCCTGTGTGACAAGCTGGGGAAGAATCTGCTGCTCACCCTGACGGTGTTTGGTGTCATCCTGGGAGCAGTGT
GTGGAGGGCTTCTTCGCTTGGCATCTCCCATCCACCCTGATGTGGTTATGTTAATAGCCTTCCCAGGGGATATACTCATGAGGATGCTAA
AAATGCTCATTCTCCCTCTAATCATCTCCAGCTTAATCACAGGGTTGTCAGGCCTGGATGCTAAGGCTAGTGGCCGCTTGGGCACGAGAG
CCATGGTGTATTACATGTCCACGACCATCATTGCTGCAGTACTGGGGGTCATTCTGGTCTTGGCTATCCATCCAGGCAATCCCAAGCTCA
AGAAGCAGCTGGGGCCTGGGAAGAAGAATGATGAAGTGTCCAGCCTGGATGCCTTCCTGGACCTTATTCGAAATCTCTTCCCTGAAAACC
TTGTCCAAGCCTGCTTTCAACAGATTCAAACAGTGACGAAGAAAGTCCTGGTTGCACCACCGCCGGACGAGGAGGCCAACGCAACCAGCG
CTGTTGTCTCTCTGTTGAACGAGACTGTGACTGAGGTGCCGGAGGAGACTAAGATGGTTATCAAGAAGGGCCTGGAGTTCAAGGATGGGA
TGAACGTCTTAGGTCTGATAGGGTTTTTCATTGCTTTTGGCATCGCTATGGGGAAGATGGGAGATCAGGCCAAGCTGATGGTGGATTTCT
TCAACATTTTGAATGAGATTGTAATGAAGTTAGTGATCATGATCATGTGGTACTCTCCCCTGGGTATCGCCTGCCTGATCTGTGGAAAGA
TCATTGCAATCAAGGACTTAGAAGTGGTTGCTAGGCAACTGGGGATGTACATGGTAACAGTGATCATAGGCCTCATCATCCACGGGGGCA
TCTTTCTCCCCTTGATTTACTTTGTAGTGACCAGGAAAAACCCCTTCTCCTTTTTTGCTGGCATTTTCCAAGCTTGGATCACTGCCCTGG
GCACCGCTTCCAGTGCTGGAACTTTGCCTGTCACCTTTCGTTGCCTGGAAGAAAATCTGGGGATTGATAAGCGTGTGACTAGATTCGTCC
TTCCTGTTGGAGCAACCATTAACATGGATGGTACAGCCCTTTATGAAGCGGTAGCCGCCATCTTTATAGCCCAAATGAATGGTGTTGTCC
TGGATGGAGGACAGATTGTGACTGTAAGCCTCACAGCCACCCTGGCAAGCGTCGGCGCGGCCAGTATCCCCAGTGCCGGGCTGGTCACCA
TGCTCCTCATTCTGACAGCCGTGGGCCTGCCAACAGAGGACATCAGCCTGCTGGTGGCTGTGGACTGGCTGCTGGACAGGATGAGAACTT
CAGTCAATGTTGTGGGTGACTCTTTTGGGGCTGGGATAGTCTATCACCTCTCCAAGTCTGAGCTGGATACCATTGACTCCCAGCATCGAG
TGCATGAAGATATTGAAATGACCAAGACTCAATCCATTTATGATGACATGAAGAACCACAGGGAAAGCAACTCTAATCAATGTGTCTATG
CTGCACACAACTCTGTCATAGTAGATGAATGCAAGGTAACTCTGGCAGCCAATGGAAAGTCAGCCGACTGCAGTGTTGAGGAAGAACCTT
GGAAACGTGAGAAATAAGGATATGAGTCTCAGCAAATTCTTGAATAAACTCCCCAGCGTATCCTATGGTAACTGATGATATAAACAAGCT
TTCTTTAAAAAGGAAAAAAATGCGTATATTTCTATGTTTACTTAATCTGTTAGCCGAGGCTTAGAGGAGCTCTTGTGAGTCAGTGATGAC
AGGCACGGTGCTGTGTCTTTGCCAAATAATGCTTTATAACCGTCTAATTTTCTCACTTGTATTATTATTTGAATGGATGCTGCTGGAGGA
ATCAGTTGGAATTGAAGACACGTTCTTGCCAGCTTCCCTTTTCTCCCAAGATGCAGAAATGTGGATGCTCTTTTCCCAGGGGACATGAGT
AAAGCAGTGTGGTACACTCCAGGGACTTGGGAAAATGAGCAAACACACAGCGTGTTATTCCTTAAAGTGTTCTCCATGTCTCGCCTTGTT
ATGCACAAGAGATTCTATTAAAAGCCTCTAGAAGTAACTCCCCTTAAAATGTCTAGTAAAGCTTGCACATGGATTGATTAAAAGCAAATA
CCTGTCTTAGGGAATTCTGACAATTTATCTTCCATATGCTCTTTAAGTAAAATGTTTCAAAGACAGTTTTAAAGGGAGCCATGCTCTTAA
AGGCAGTTGATTAAAGAACCTGTTACATCTCTGCCTTACCCTGTGTAATCTGTGAGAACAATGGTTGAAATTTCAAAGTATGTTTCATTA
TTCTTTCTAAATTTGATAATTGATTAGGAAGTATTTTATATATAACCACTGTAGATATTGACAAAAGTAAGAGAGCACAGTCAACATAAA
GTTTAACCAGAGTTAAATATTCAAATTTATTTATGTTCGGTTTGCCTTCACCTGGTGTAGTAAAATCAAATGAGATTATTTGGTATGTGT
TTTGCTTTGTTTAACCCAAAAGATTATTTTTTGGTTCCTAAAGAAAAAGATATTTTTAATCTGTCAATTATTTCAGTCATCATCTCATCG
TCCTAGAAAGCCTGGTCATTTTACTGTCCTCACACATGGAAGACACTTGTGTTGGCTGTGCCTCTTTTAATGTCATCTCTTGATGAAACA
AAAATACTGGTATTTATCCAATATGTTGAAAGCGTTTTGTTATCTTCTATCAAAGCACATAAAACCAGTTATAGGACACAGTTGGAAGCA
GAGCCAGTCTTCCTCCTCAGTCTTCTCAGTAGAAAGGAACAGAAAACAAACATCTGTGCAAAACCCTATAAAAGTGATATTCCTATGGCA
GAGTCCAGGCAGCCTTGAACAATGACATGGCAACAAAGGATGGCTCTGTACAACTTCACAGATGGAATCTTGTTTAAGGCTGTGAAGTTT
TAAGGAATAAATAATATAATTGGTGTAGCACAGTGCCTTGCATGCAGTAGGCAGCCAACAAATCCTTAATGATTGGTAATGCAAGCTAAA
ATTTTTAATGTCTCTACTATCCTTTTTTATTGAATAACGCACAGTATTTTCCTAAGGTTGCTGGGTTTGGGAGTAAGCTTGGGACTTGAA
TCATTGAGAAATAAAGCACATTTGACTCTAAGAAGTATGTAGAACCTTGTTTATAGGTGAGAATAGGCTGTATTATATGAAACCAGCGGA
GGGATGCTGAGACAGTCATGGTTTATAGAATCCAAATTCTCTGAGATGAGGGTGCTTATGGACCTCAAATAGCCTTTCTTATCTGCTCCT
TGTGACTTCTCTCTTTTAAATCAGATACCTTTGAAACATACAAGAGACATGAGATTCCAGTTGTTTTTGTCTCCTAAACCCTAGTGATTT
TTGGATAAGGATCACTACTGAACAGTATTAGGCAACTTTTCATTTTTGCTTTTCAAATGACATTGGTCTTTATTTCCAGTAGATGGGCAG
TAAACAGGGTCAGGGTGGTCAAGGGATATGATTAAGTGTAGTAGTAGAAAATGCATTCTTTTTTTTTTTTTTTTTTTAGACAGAGTCTTG
CTCTGTTGCTCAGGCTGGAGTACAGTGGCACGATCTCAGCTCACTGCACTGCAATGTCCACCTCTCTAGTTCAAGCGATTCTCCTGTCTC
AGCCTCCCGAGTAGCTGGGACTACAGGCACATGCCACCATGCCTGGCTAATTTTTTGTATTTTTAGTACAGATGGGTTTCATTATGTTAG
CCAGGATGGTCTCGATCTCCTGACCTCATGATCCACCCGCCATGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGTGCCCGGC
CAGAAAATACATTCTTTACAGCAAATGTTATAGGTTAAGGAGACAGTTCCTGGGTTTAGCTGTGAAACTGTTTAGGATTTTCTTTAAGTG
GTGTTCCCAAGAGCTTTTTTCTGGTAAGTTGGAGGCTATAGGCAAAGCGTCTAGGAGCTTGTTGTTTTTTGCTATGGAAGGCCAGCTTTG
GGATCTATATACATGGGCATGTTTCTCAATGGAGTGGTCACAGGATTCTCTTCTCAGAACTCTGCCTGAAACCTTTCCGGTGTGTTTTGT
CTTCAACTTTTTCCTAGCTATCCTATTAGCCTGTAAATATGTCAGCAGACAATGTGTTTGGAAGAAACAAGGTGTACAACTTCACAAAGC
AAGTTTTTTCTGGTCTGAGACTTACTGTGTGCAGGAAGTCTCGTGAGAATATACTTAGAAAATCACACTTATCTGGAAATTCAATAAGTC
ATATTAAAAATATACAATTTCTTGAACTCAGGACTAGCCTGAAAATCCAAAATGCATGTAGAGTTGACATGTTGACATATGTCTATGTCC
TCTGTTTTTATTTAAGCCTCATTTATTTCTCCCTTGCCATGCCCATTTGGGATTTTCTTTGCCCAGCATATGTGCCATAAACAGAACAAA
TGGATCCAGGGTATACCTCTAATAACCTTTATCTAAATAGAATACATTTAACCTGTCAATTATATGTATAGATTTATCCTAATTGGTTCA
ACATATATATGAATGCTTGTAATAGTCTGTTACTATTTGATAATGCATAAATGTTATATTTATATACAGTTACAGCAGGCCAGAAACATA
CATACACTGCATCCTGTAAGGTCTGTAAATCAGGGCTTCGGCAATGCCATTTTGCTATAGACTCATTCATGTTTTTTAGGAATCAGAATC
ATTTCAGGAGAAAACCAACTAAGTAGACTTTAATTCTTCTCTTTCTCATTCTTGCCCTTTGAGAAACCCAAGTGGAATCATCACTTAATT
ACTTACTCAAATTCAATGAATCAAATCCAATCCAATCAGTGAGAAGAATAGCTTATCTTTCAAGGTAATACTTTACCTTAGATCTTTGAG
GGCATGCTTCCCATACAAAGAGCATCAGAAAATCAGGGCAATCATCTAGATCTCACAGATCTTCAACATAGGACTCTAGGTTATGAGAGC
TGAACCACATAGCTATCAGTTTCAGTTTTTACTTCCTATTGAGTGTGTAGAAACACAGCCTATGGTTTTGCTGTCTGCGGAAGTTACCAT
ACCCTGTAAAAGACAAATATTTCTTTCTCCTCTCGAACCACTAGTCAGCCTGGATATTCATGAAAGCTGAAAGAAGGGGTGCCAAAATGC
CTAGCTCCTGGATTTAGACTCATGGAATATGAGAAAGGCTTAGGGAAAATTCAAGTCATGGGGAGATTCCTGCTAGGTGATGCCAGGAAT
CTCAATGACCTGTTGATTAGAGGGTCTCTGGTCATTTCCACTTGTGTGTGGAGAAATACATCATTTGCATATGTATCTAGTCAAGAAGCC
CTTTTGGAGCAAAGTGGTTGGGAAACTCATTTACTGGGTCCACCAAAGGAAACCCAATTCTGCCATGTTTTTGCAAATACTACACGTCCC
TTTGCTCTCAATAGCAAAAGTGATGTTATAGTTTTTTTTACTTTTGTCAGAATCAAGGCTTCGGCCACCTGTGCAATATTTTCCCATGGA
ATGCAGCAGTAAATCCAAGTAGGTATATCCGTGCTCAGAGAGAATTCTCCATAGTTCTGACTCCTGAAAAACAAGTCTCATTAGCTCTCA
TCTAGTTTGATGACTAAAAGTGCACAGCAGTTATACCCCAGTGGAAGTGATTTTTCTCACCTAGCTGCTCTCTAACTCTTACGGCTATCT
AGTTGTCTGAGCTGCTGGTTTGTTTTACTTATTCTCCAACTGAACTCATTCCAAACCAAGAAAAAGGACCAAATGAAATTTTCAGTTATT
ATCATACTTGCTCCTTGAATAAGAATGCTAGAGTCTGGAGGCAGAAGAAGACTAAGTTAAAAAAAAAACAGCCTGAAGGAATTCTGGAGT
GAGTTTTGTAAGTCTAATTGTCAAAGAAGATAAATGGTCTCAGTATCTGTAGTAATTTCTGGTTAAGCCTAGAGGGATCACTGAGTGCCA
ATCCAAGCAGGTGGCACTAGAGGCAGATTGTTCTCCTAGCATAGAGTGAGTTTCCAGCTGCTCATGACACATTTTCTTATGATTTTCCCT
AAAAGAAAACCAAATTTTCTACTCCACCTCTTCCTTTCCTATCATTCCACTTATTGTTGCTGCTTTGCTAACAGCCAGCTTAGTAAGCCA
TCACACAAGTTAGTGTGAGGCTTGGTTTTAAAATAGATAACAGAGAATCTTGATTAAATAGTATCCAACTTTGTAGCATAACACAGCTAA
TTCAGGCAATGACATAGAGATGATAAGAAACAACATGGTTTGGTAGAGGGAACATTTGATTTAGACTCTGCCCATTTTTAGCTGTATGAC
TTACATAAGTCATTTTGTGTCCAAGCCTCATTTTCTCCCATATGAAAAGTGAAGGGGTTGGATTAAATGACTAAAATCCCCTTCCAGCCC
TATGAGCCCAATGTATTATGATCTCTGCTTTGTTTCCTTCTTAAGAGGCTTCCTACTATAAAATGTGACCTATTTACATTTTAAGTTGAA
GTAGCCCACAATAATGAATAATCAATTTAGATTTTTCTCATCTCCTTTGGGAGAAATTAAATTCAAGCCTCTATTCATTTGATGTTTTAC
AACAAGCTTCAAAGTTGGCCATGTTCATTCACAGTTTGATATTTTGAGACACCAATAAAAGTTTTTTAATAAAAGTTCCCTTGACTTAAA
CTCACCTTCCTAATAGAAGTAGTGATTTGGCTCACGGAAAAATGTTTCCAGAGTCAACATGAGAGGACTGGATGAACCTACAGCCTCACT
CAAGCTGTTGCATCATTGCTGCTGTAGCAACAGAGCCCTCTCTGAATACCCAAAACACACAATTTTCTCCAACAATTCTAATTGCCCACC
CAGTATGGGAATTTGAGAGCCTTTGGTGAATAACCTTGATCACTCTTTTGAAATTTGGTACAACACTTGCACAATCACGGCAACTGTTTG
TAAATATCTTTTCTTCTCCGCCAGTATGTAGACATGCACACCCATTCACAAGTAAGCCCGCAAATTCATTTTCACATTTTCCTCTTGGTT
TGTTTTTATCATGGGTATCACATTGCAGGAAGAGATGCTCTAACTTACAAGAATGGAATTTTCTGACTATCATTGCCCTCTTCAAGGCCT
GATTAGTTTGTAGGGTGGATGGGATACAATGCATGGTCTACAAGGTCCATGTCACCAGCCATGATCTTTAAACAACCTCTTGCACTTTCT
GGCACTGCTGCAATGGCCCATGGTGGACACCTCTGCTGTTTGTCCAAACTTCTGCTAAATAGAGTAGTGTTGGTATTTGTTGTGTTGTGA
ACTCCTTTGTTGTCAGAGAAGACTTCAGCTCTTCAGGTTTGCAAGGGCAAGATGTAAAGCTAGGACTGAAAGGATTGGGTTTTGTTTTTC
GGCCGGCTTTTTTCCATTAGTGCAAAAAACCTGATGCAAGGGCAGCAAGATAAACACAATTTCTTCATTGACCCAGATAAGAACCTGTAG
AAAAGTGAGAGATGCCCCTAAGTTCCTATTTCATTTATCCTAAATAATATCCTGAATAACTACTGATCAGTTTTTTTCTATGTCCAGCCT
TGCTTCACTTTCCAACCTCCAGGCCAAATATTCATTTTGATATTTTACAAAATCCTTCTGGTTTTTACACAGGGCCCTTTTGTGCTGAGA
ATAAAACCAGCTATTGGAACAGACCTCACTGCTTTGTAGAGTCAGAAGTTGACCTAGAGAATGGGTAGCAACAGGTCCTCAGTTTCTCTG
GAGACACCCCCAATCCTTGGGTGAGTGTTGAAACCTGACAACTGACTGTTAGCCTTGTCATCATCCTCACTGGAGATGGAGATGTTGCAG
TCGGAGCCTCACTCCTTCTGGGGCACTGTTTCTTCTCATGGCAACCATTTTGCCTGCCTGGAAACAGCCTGTTGCCTTTGCTAGGGGGCA
AATACACACACTAGCCAAGGAAGTTGGTCCAGCACATCTCTGAGGTTTCTCCCCCATGGACCCATGGAGCGAATTCCCTGAGATAAATGA
TCAGAAAGTTGGCTGTCTGGTGGTTTAATACTCCATAAGAGTTACTTCCCTTATAGAAAGTCATCCTTTGGCATCTAGATTTTTCTACAA
ATCACCTTAACTCCCTCCCTTTCTCTTTCTCCTGGAAAACCTCAGCATTGCATCTCCATGTTGCACAACACAGATCAGATTATCTGGTCA
CTATAGAGATTTGTATATAAAAAAACTACTTTTTTGAGGATTTTGTATATTGTTTTTCTATTTGTTTTCTACAGCTTGAGGAAAGAGCTG
GCAAACTGTGAATCTAACTTGATCTTGTTGCCAGCAGATATATTTTGGCTTCCTGGTAAGAGTCTGTGTTACCAGGGACAATATATTGCC
CTCTGATCAGTATTGCACCCTAAATCCACAAATTCCTCCAGCCCAGTCTTACATTTTTTTAAACAAATCCCCTAGCTTGTTTGCTATTAT
TTATAAAGAGCATTAGAAAATGTATTTATAGACCTGGATGTTATATGTTTAATATTAATTTAGCCTTTAATAATGTTATAGGTTTGTAAC
TATTCTTCAGAAATTATAAAGAACTCAGTGTAGACTGAATTAATCTATTTAGTATCTGTAATTTTGCAGACATATTTTCTTACAGTATTT
TCTATGTAACCACACATGTAGAATTATAACTAATTAGAGCACAAGAAGTTTCTTCAGCAATTTAGAGCTACCAATTGTTTCTTGACTATA
TAGTCACATTTGACAAATTTAAGAACCCAGTCTTTAGTGATGCAATAAACAAAATGAACCATTAAGAACAAGGAATTGCTTAAATCCCTT
AGCTGGTGAGGATATACATCTAAATAATTCATCTTTCTAACTCAAGGAATGGTGCTGATTTTTTAAATGTTTGACACCAGGCCTTGTTTT
TCCAGCTGAGCATTCTCATTTTGCTTTTCTCTAAGACTATCAAAGACAAGGTATTAATAGTAGGATTATTCCTAGATCAGAATGTTTCAT
ACATTCCTAAAGGTTTATGTGGAAATTGGCTTAGGAAAACTTTGAGTAGCAGAGACTGAGGATGAGTGCTAGAGATGAAATCAGGACAGA
TTTGTTGCAGTTAATTCTTGCCAAGCAAATTAGTGGTAAATGTCACATTGTTATGTGAATTGAGCACATATTTTTAAAGAAAGTTTACAA
AAAATTTTTAGAACCAACTATGAGGCAATACTGTATCACTGGGGGCTGGGAGTGGGGGCTTAGAATCATACTGAAATTGTTTAAAAGCAG
CCCAGGTAGTTTCTGTCCTCAGGTGAATAACAGACTATATAACTTCCCCGAAAGGTAAAACGATAGCCACTGCAGAGACGAGGTGTCTTC
CTTCCACCAAATACTTTCTGAGATGGTGGTAGGAGTAGTATTTTTACCGTGGTTTAAAAAGTAGTCAGTTACATAGAAAGTGTATTGGTA
TGTATTTGAACCTGCTCTTCATTAAACAAACAGATTAGATGTACCCTCGACTGGCAATAATTGTATCTATTTTCAAGTACAGCTAGCTGT
CAAAGCATGAAGCTCTTGTGTATACACACTGACACTTGGTTCACGCATGAAGAACAGTGCCTATGCACTTTGTGTAGCTATAATGTAGGT
ATCTAGGTGTAATTTCAGTGAAATGGTGTATAGATGTATTGTAATTTAAATGTATATGTTATTTTTGGCTATTCATCTAAATGCAGTAGA
CATGTTGATCGGTGTTTTGCAAACATTTCTTTTTCCTTCTTAGATAACTAGTCGTGAATCATTTCTCCTCTTTCTCAGTGTGGCTTGGGA
ATATATATGAGTGAAGAATTTATCTGTGAATCCTTTGTACTGATGATTGTTTGAAAGTCTGTGTGTGTCCAGCACCTTTGTAAATACACA
ATTCAGAGCAGGGATGGGCTGGGTGTGTGTCCTGGTTCTTAGTGAAAGGTCATCTCATGTCTGTTTAATACATGGTGAATGCAACTGTGG
AACTTTTGATTACCTAGACTTAGGTAGGTTTAGAATGAGAACATCCATCTACAGTCCTCCTTTGCTTGGTGGATTGGGCTCAGAGGAACA
AAAAGTTAGTCTGACTCTGTGCATATTAGCATCATGTCTTTAGAGAAAGGTCAGCCTCTCTGGTTGCCAAATACTCATCATGATGCTCAT
GACTTAAAGGTTCTGAGGAGCCTTGTCTCCCTTGGATTTTTGAGTCAGGGTACAGGAAAAAACATTGCTGACTAACTAACTGCAAATGCA
TCTGCAGGTGAAACCCTACGAAAGCACAGTTCTGGCTATAAACTTCAGAGTTCTCTGTAAAAAACTTAGAGCACTAGAAGCACAGGAATA
GTGAGTGTACAGCTTATGCGGTTGTAGAGGGGCAACTGATGAACACAGGTCCCACATATATGAGGGAGTATGACGTTCTCTACCTAATAT
GTTCTGTGTGCATGTTTTGAATGATTGAAGATGGGATTAACTAATGCAAGTTTACAGTTGCCTCCTAAAACACACATTCTGTATAATTAT
CGCTAAATACAATGCTGTGAGGTCTATAGTTCCTGTAACCCCTTTCTCCTCCCCAAGGACAGAGAAGAACTAGCCATGTGCTATAGGGAA
CCCTGAGTGCCCTACTCTTTTCCCAAGAAGGGTAAAGCCTACAATATCATCAGGGGGCATGAAGCACATTAATTTGCAGTGGCTGCTTCA
TATGAGGAGATATGGTGGACAGGCTAATTTTTCCTTGAAAATGTGGCTTCTTCAACTCCTTTCAAATTTAGGATGGAATACTTCCTGAAA
TAAAACTGGGCTTTATGCAGGATTCTCTTTGAAAATTCTTGTATGTCCAGAACAAAAGATAAAACTAATTGTATTCCTCACATTCACAAT
CCCCATTGGTCTGAAGTCACGTAGCACAGAGCATCTATAGCACATAGTGTTTAAAGACTAATGAATGCAAAAAGATAAAATCTTCAACTA
ATTTTTGAATTGTTTCTCATATATGCTACTAGAAAATGCCTTGTTGATGAAGCACATTTTGGGTAGTTGAGGTCTTTTGTTTTCGCCTTT
AGCTTTCTAAGCTTTCTTACAATGTGGACTGATTACTGTAACATTTCACGTGTAAAATAACTGGATATTCTTTATATACTGGAAATAACC

>In-frame_PAMR1_ENST00000378880_chr11_35461175_-_SLC1A2_ENST00000278379_chr11_35339063_-_12942nt
AGGGCAAAGCCAGCTCCCGTCTCAGCCTCCCGTAGGAAGATCTCCCGGCCTCACCTGAGCGCCCCGCAGCCCTGGGTACCTCTGCTCCCG
CCCAGGGTCCTATGGCCCCTCCTCCCAGCACCCAACACTGGGACCCCACCTGTACCCAGGCTGGCCTCCCTCCCCCGCAGCTTCCTTTGC
AGCCGCCGTCCGCGGGTCTCCAGGCGTGGCCACACCTCCCGGGGCCCCGCAAGGGTTAAGGCAGCAGAGAGGAGAGGTTTGGGCTGACGT
CGCTCTGGCTGAAGGTGGTTCCCCTCAGATGAGGATGGGAGAGCCTGGCGAGCTGAAACCCGAGCTCCCGCTCAGCTGGGGCTCGGGGAG
GTCCCTGTAAAACCCGCCTGCCCCCGGCCTCCCTGGGTCCCTCCTCTCCCTCCCCAGTAGACGCTCGGGCACCAGCCGCGGCAAGGATGG
AGCTGGGTTGCTGGACGCAGTTGGGGCTCACTTTTCTTCAGCTCCTTCTCATCTCGTCCTTGCCAAGAGAGTACACAGTCATTAATGAAG
CCTGCCCTGGAGCAGAGTGGAATATCATGTGTCGGGAGTGCTGTGAATATGATCAGATTGAGTGCGTCTGCCCCGGAAAGAGGGAAGTCG
TGGGTTATACCATCCCTTGCTGCAGGAATGAGGAGAATGAGTGTGACTCCTGCCTGATCCACCCAGGTTGTACCATCTTTGAAAACTGCA
AGAGCTGCCGAAATGGCTCATGGGGGGGTACCTTGGATGACTTCTATGTGAAGGGGTTCTACTGTGCAGAGTGCCGAGCAGGCTGGTACG
GAGGAGACTGCATGCGATGTGGCCAGGTTCTGCGAGCCCCAAAGGGTCAGATTTTGTTGGAAAGCTATCCCCTAAATGCTCACTGTGAAT
GGACCATTCATGCTAAACCTGGGTTTGTCATCCAACTAAGATTTGTCATGTTGAGCCTGGAGTTTGACTACATGTGCCAGTATGACTATG
TTGAGGTTCGTGATGGAGACAACCGCGATGGCCAGATCATCAAGCGTGTCTGTGGCAACGAGCGGCCAGCTCCTATCCAGAGCATAGGAT
CCTCACTCCACGTCCTCTTCCACTCCGATGGCTCCAAGAATTTTGACGGTTTCCATGCCATTTATGAGGAGATCACAGCATGCTCCTCAT
CCCCTTGTTTCCATGACGGCACGTGCGTCCTTGACAAGGCTGGATCTTACAAGTGTGCCTGCTTGGCAGGCTATACTGGGCAGCGCTGTG
AAAATCTCCTTGAAGAAAGAAACTGCTCAGACCCTGGGGGCCCAGTCAATGGGTACCAGAAAATAACAGGGGGCCCTGGGCTTATCAACG
GACGCCATGCTAAAATTGGCACCGTGGTGTCTTTCTTTTGTAACAACTCCTATGTTCTTAGTGGCAATGAGAAAAGAACTTGCCAGCAGA
ATGGAGAGTGGTCAGGGAAACAGCCCATCTGCATAAAAGCCTGCCGAGAACCAAAGATTTCAGACCTGGTGAGAAGGAGAGTTCTTCCGA
TGCAGGTTCAGTCAAGTGCCAACAATATGCCCAAGCAGGTGGAAGTGCGAATGCACGACAGTCATCTTGGCTCAGAGGAACCCAAGCACC
GGCACCTGGGCCTGCGCCTGTGTGACAAGCTGGGGAAGAATCTGCTGCTCACCCTGACGGTGTTTGGTGTCATCCTGGGAGCAGTGTGTG
GAGGGCTTCTTCGCTTGGCATCTCCCATCCACCCTGATGTGGTTATGTTAATAGCCTTCCCAGGGGATATACTCATGAGGATGCTAAAAA
TGCTCATTCTCCCTCTAATCATCTCCAGCTTAATCACAGGGTTGTCAGGCCTGGATGCTAAGGCTAGTGGCCGCTTGGGCACGAGAGCCA
TGGTGTATTACATGTCCACGACCATCATTGCTGCAGTACTGGGGGTCATTCTGGTCTTGGCTATCCATCCAGGCAATCCCAAGCTCAAGA
AGCAGCTGGGGCCTGGGAAGAAGAATGATGAAGTGTCCAGCCTGGATGCCTTCCTGGACCTTATTCGAAATCTCTTCCCTGAAAACCTTG
TCCAAGCCTGCTTTCAACAGATTCAAACAGTGACGAAGAAAGTCCTGGTTGCACCACCGCCGGACGAGGAGGCCAACGCAACCAGCGCTG
TTGTCTCTCTGTTGAACGAGACTGTGACTGAGGTGCCGGAGGAGACTAAGATGGTTATCAAGAAGGGCCTGGAGTTCAAGGATGGGATGA
ACGTCTTAGGTCTGATAGGGTTTTTCATTGCTTTTGGCATCGCTATGGGGAAGATGGGAGATCAGGCCAAGCTGATGGTGGATTTCTTCA
ACATTTTGAATGAGATTGTAATGAAGTTAGTGATCATGATCATGTGGTACTCTCCCCTGGGTATCGCCTGCCTGATCTGTGGAAAGATCA
TTGCAATCAAGGACTTAGAAGTGGTTGCTAGGCAACTGGGGATGTACATGGTAACAGTGATCATAGGCCTCATCATCCACGGGGGCATCT
TTCTCCCCTTGATTTACTTTGTAGTGACCAGGAAAAACCCCTTCTCCTTTTTTGCTGGCATTTTCCAAGCTTGGATCACTGCCCTGGGCA
CCGCTTCCAGTGCTGGAACTTTGCCTGTCACCTTTCGTTGCCTGGAAGAAAATCTGGGGATTGATAAGCGTGTGACTAGATTCGTCCTTC
CTGTTGGAGCAACCATTAACATGGATGGTACAGCCCTTTATGAAGCGGTAGCCGCCATCTTTATAGCCCAAATGAATGGTGTTGTCCTGG
ATGGAGGACAGATTGTGACTGTAAGCCTCACAGCCACCCTGGCAAGCGTCGGCGCGGCCAGTATCCCCAGTGCCGGGCTGGTCACCATGC
TCCTCATTCTGACAGCCGTGGGCCTGCCAACAGAGGACATCAGCCTGCTGGTGGCTGTGGACTGGCTGCTGGACAGGATGAGAACTTCAG
TCAATGTTGTGGGTGACTCTTTTGGGGCTGGGATAGTCTATCACCTCTCCAAGTCTGAGCTGGATACCATTGACTCCCAGCATCGAGTGC
ATGAAGATATTGAAATGACCAAGACTCAATCCATTTATGATGACATGAAGAACCACAGGGAAAGCAACTCTAATCAATGTGTCTATGCTG
CACACAACTCTGTCATAGTAGATGAATGCAAGGTAACTCTGGCAGCCAATGGAAAGTCAGCCGACTGCAGTGTTGAGGAAGAACCTTGGA
AACGTGAGAAATAAGGATATGAGTCTCAGCAAATTCTTGAATAAACTCCCCAGCGTATCCTATGGTAACTGATGATATAAACAAGCTTTC
TTTAAAAAGGAAAAAAATGCGTATATTTCTATGTTTACTTAATCTGTTAGCCGAGGCTTAGAGGAGCTCTTGTGAGTCAGTGATGACAGG
CACGGTGCTGTGTCTTTGCCAAATAATGCTTTATAACCGTCTAATTTTCTCACTTGTATTATTATTTGAATGGATGCTGCTGGAGGAATC
AGTTGGAATTGAAGACACGTTCTTGCCAGCTTCCCTTTTCTCCCAAGATGCAGAAATGTGGATGCTCTTTTCCCAGGGGACATGAGTAAA
GCAGTGTGGTACACTCCAGGGACTTGGGAAAATGAGCAAACACACAGCGTGTTATTCCTTAAAGTGTTCTCCATGTCTCGCCTTGTTATG
CACAAGAGATTCTATTAAAAGCCTCTAGAAGTAACTCCCCTTAAAATGTCTAGTAAAGCTTGCACATGGATTGATTAAAAGCAAATACCT
GTCTTAGGGAATTCTGACAATTTATCTTCCATATGCTCTTTAAGTAAAATGTTTCAAAGACAGTTTTAAAGGGAGCCATGCTCTTAAAGG
CAGTTGATTAAAGAACCTGTTACATCTCTGCCTTACCCTGTGTAATCTGTGAGAACAATGGTTGAAATTTCAAAGTATGTTTCATTATTC
TTTCTAAATTTGATAATTGATTAGGAAGTATTTTATATATAACCACTGTAGATATTGACAAAAGTAAGAGAGCACAGTCAACATAAAGTT
TAACCAGAGTTAAATATTCAAATTTATTTATGTTCGGTTTGCCTTCACCTGGTGTAGTAAAATCAAATGAGATTATTTGGTATGTGTTTT
GCTTTGTTTAACCCAAAAGATTATTTTTTGGTTCCTAAAGAAAAAGATATTTTTAATCTGTCAATTATTTCAGTCATCATCTCATCGTCC
TAGAAAGCCTGGTCATTTTACTGTCCTCACACATGGAAGACACTTGTGTTGGCTGTGCCTCTTTTAATGTCATCTCTTGATGAAACAAAA
ATACTGGTATTTATCCAATATGTTGAAAGCGTTTTGTTATCTTCTATCAAAGCACATAAAACCAGTTATAGGACACAGTTGGAAGCAGAG
CCAGTCTTCCTCCTCAGTCTTCTCAGTAGAAAGGAACAGAAAACAAACATCTGTGCAAAACCCTATAAAAGTGATATTCCTATGGCAGAG
TCCAGGCAGCCTTGAACAATGACATGGCAACAAAGGATGGCTCTGTACAACTTCACAGATGGAATCTTGTTTAAGGCTGTGAAGTTTTAA
GGAATAAATAATATAATTGGTGTAGCACAGTGCCTTGCATGCAGTAGGCAGCCAACAAATCCTTAATGATTGGTAATGCAAGCTAAAATT
TTTAATGTCTCTACTATCCTTTTTTATTGAATAACGCACAGTATTTTCCTAAGGTTGCTGGGTTTGGGAGTAAGCTTGGGACTTGAATCA
TTGAGAAATAAAGCACATTTGACTCTAAGAAGTATGTAGAACCTTGTTTATAGGTGAGAATAGGCTGTATTATATGAAACCAGCGGAGGG
ATGCTGAGACAGTCATGGTTTATAGAATCCAAATTCTCTGAGATGAGGGTGCTTATGGACCTCAAATAGCCTTTCTTATCTGCTCCTTGT
GACTTCTCTCTTTTAAATCAGATACCTTTGAAACATACAAGAGACATGAGATTCCAGTTGTTTTTGTCTCCTAAACCCTAGTGATTTTTG
GATAAGGATCACTACTGAACAGTATTAGGCAACTTTTCATTTTTGCTTTTCAAATGACATTGGTCTTTATTTCCAGTAGATGGGCAGTAA
ACAGGGTCAGGGTGGTCAAGGGATATGATTAAGTGTAGTAGTAGAAAATGCATTCTTTTTTTTTTTTTTTTTTTAGACAGAGTCTTGCTC
TGTTGCTCAGGCTGGAGTACAGTGGCACGATCTCAGCTCACTGCACTGCAATGTCCACCTCTCTAGTTCAAGCGATTCTCCTGTCTCAGC
CTCCCGAGTAGCTGGGACTACAGGCACATGCCACCATGCCTGGCTAATTTTTTGTATTTTTAGTACAGATGGGTTTCATTATGTTAGCCA
GGATGGTCTCGATCTCCTGACCTCATGATCCACCCGCCATGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGTGCCCGGCCAG
AAAATACATTCTTTACAGCAAATGTTATAGGTTAAGGAGACAGTTCCTGGGTTTAGCTGTGAAACTGTTTAGGATTTTCTTTAAGTGGTG
TTCCCAAGAGCTTTTTTCTGGTAAGTTGGAGGCTATAGGCAAAGCGTCTAGGAGCTTGTTGTTTTTTGCTATGGAAGGCCAGCTTTGGGA
TCTATATACATGGGCATGTTTCTCAATGGAGTGGTCACAGGATTCTCTTCTCAGAACTCTGCCTGAAACCTTTCCGGTGTGTTTTGTCTT
CAACTTTTTCCTAGCTATCCTATTAGCCTGTAAATATGTCAGCAGACAATGTGTTTGGAAGAAACAAGGTGTACAACTTCACAAAGCAAG
TTTTTTCTGGTCTGAGACTTACTGTGTGCAGGAAGTCTCGTGAGAATATACTTAGAAAATCACACTTATCTGGAAATTCAATAAGTCATA
TTAAAAATATACAATTTCTTGAACTCAGGACTAGCCTGAAAATCCAAAATGCATGTAGAGTTGACATGTTGACATATGTCTATGTCCTCT
GTTTTTATTTAAGCCTCATTTATTTCTCCCTTGCCATGCCCATTTGGGATTTTCTTTGCCCAGCATATGTGCCATAAACAGAACAAATGG
ATCCAGGGTATACCTCTAATAACCTTTATCTAAATAGAATACATTTAACCTGTCAATTATATGTATAGATTTATCCTAATTGGTTCAACA
TATATATGAATGCTTGTAATAGTCTGTTACTATTTGATAATGCATAAATGTTATATTTATATACAGTTACAGCAGGCCAGAAACATACAT
ACACTGCATCCTGTAAGGTCTGTAAATCAGGGCTTCGGCAATGCCATTTTGCTATAGACTCATTCATGTTTTTTAGGAATCAGAATCATT
TCAGGAGAAAACCAACTAAGTAGACTTTAATTCTTCTCTTTCTCATTCTTGCCCTTTGAGAAACCCAAGTGGAATCATCACTTAATTACT
TACTCAAATTCAATGAATCAAATCCAATCCAATCAGTGAGAAGAATAGCTTATCTTTCAAGGTAATACTTTACCTTAGATCTTTGAGGGC
ATGCTTCCCATACAAAGAGCATCAGAAAATCAGGGCAATCATCTAGATCTCACAGATCTTCAACATAGGACTCTAGGTTATGAGAGCTGA
ACCACATAGCTATCAGTTTCAGTTTTTACTTCCTATTGAGTGTGTAGAAACACAGCCTATGGTTTTGCTGTCTGCGGAAGTTACCATACC
CTGTAAAAGACAAATATTTCTTTCTCCTCTCGAACCACTAGTCAGCCTGGATATTCATGAAAGCTGAAAGAAGGGGTGCCAAAATGCCTA
GCTCCTGGATTTAGACTCATGGAATATGAGAAAGGCTTAGGGAAAATTCAAGTCATGGGGAGATTCCTGCTAGGTGATGCCAGGAATCTC
AATGACCTGTTGATTAGAGGGTCTCTGGTCATTTCCACTTGTGTGTGGAGAAATACATCATTTGCATATGTATCTAGTCAAGAAGCCCTT
TTGGAGCAAAGTGGTTGGGAAACTCATTTACTGGGTCCACCAAAGGAAACCCAATTCTGCCATGTTTTTGCAAATACTACACGTCCCTTT
GCTCTCAATAGCAAAAGTGATGTTATAGTTTTTTTTACTTTTGTCAGAATCAAGGCTTCGGCCACCTGTGCAATATTTTCCCATGGAATG
CAGCAGTAAATCCAAGTAGGTATATCCGTGCTCAGAGAGAATTCTCCATAGTTCTGACTCCTGAAAAACAAGTCTCATTAGCTCTCATCT
AGTTTGATGACTAAAAGTGCACAGCAGTTATACCCCAGTGGAAGTGATTTTTCTCACCTAGCTGCTCTCTAACTCTTACGGCTATCTAGT
TGTCTGAGCTGCTGGTTTGTTTTACTTATTCTCCAACTGAACTCATTCCAAACCAAGAAAAAGGACCAAATGAAATTTTCAGTTATTATC
ATACTTGCTCCTTGAATAAGAATGCTAGAGTCTGGAGGCAGAAGAAGACTAAGTTAAAAAAAAAACAGCCTGAAGGAATTCTGGAGTGAG
TTTTGTAAGTCTAATTGTCAAAGAAGATAAATGGTCTCAGTATCTGTAGTAATTTCTGGTTAAGCCTAGAGGGATCACTGAGTGCCAATC
CAAGCAGGTGGCACTAGAGGCAGATTGTTCTCCTAGCATAGAGTGAGTTTCCAGCTGCTCATGACACATTTTCTTATGATTTTCCCTAAA
AGAAAACCAAATTTTCTACTCCACCTCTTCCTTTCCTATCATTCCACTTATTGTTGCTGCTTTGCTAACAGCCAGCTTAGTAAGCCATCA
CACAAGTTAGTGTGAGGCTTGGTTTTAAAATAGATAACAGAGAATCTTGATTAAATAGTATCCAACTTTGTAGCATAACACAGCTAATTC
AGGCAATGACATAGAGATGATAAGAAACAACATGGTTTGGTAGAGGGAACATTTGATTTAGACTCTGCCCATTTTTAGCTGTATGACTTA
CATAAGTCATTTTGTGTCCAAGCCTCATTTTCTCCCATATGAAAAGTGAAGGGGTTGGATTAAATGACTAAAATCCCCTTCCAGCCCTAT
GAGCCCAATGTATTATGATCTCTGCTTTGTTTCCTTCTTAAGAGGCTTCCTACTATAAAATGTGACCTATTTACATTTTAAGTTGAAGTA
GCCCACAATAATGAATAATCAATTTAGATTTTTCTCATCTCCTTTGGGAGAAATTAAATTCAAGCCTCTATTCATTTGATGTTTTACAAC
AAGCTTCAAAGTTGGCCATGTTCATTCACAGTTTGATATTTTGAGACACCAATAAAAGTTTTTTAATAAAAGTTCCCTTGACTTAAACTC
ACCTTCCTAATAGAAGTAGTGATTTGGCTCACGGAAAAATGTTTCCAGAGTCAACATGAGAGGACTGGATGAACCTACAGCCTCACTCAA
GCTGTTGCATCATTGCTGCTGTAGCAACAGAGCCCTCTCTGAATACCCAAAACACACAATTTTCTCCAACAATTCTAATTGCCCACCCAG
TATGGGAATTTGAGAGCCTTTGGTGAATAACCTTGATCACTCTTTTGAAATTTGGTACAACACTTGCACAATCACGGCAACTGTTTGTAA
ATATCTTTTCTTCTCCGCCAGTATGTAGACATGCACACCCATTCACAAGTAAGCCCGCAAATTCATTTTCACATTTTCCTCTTGGTTTGT
TTTTATCATGGGTATCACATTGCAGGAAGAGATGCTCTAACTTACAAGAATGGAATTTTCTGACTATCATTGCCCTCTTCAAGGCCTGAT
TAGTTTGTAGGGTGGATGGGATACAATGCATGGTCTACAAGGTCCATGTCACCAGCCATGATCTTTAAACAACCTCTTGCACTTTCTGGC
ACTGCTGCAATGGCCCATGGTGGACACCTCTGCTGTTTGTCCAAACTTCTGCTAAATAGAGTAGTGTTGGTATTTGTTGTGTTGTGAACT
CCTTTGTTGTCAGAGAAGACTTCAGCTCTTCAGGTTTGCAAGGGCAAGATGTAAAGCTAGGACTGAAAGGATTGGGTTTTGTTTTTCGGC
CGGCTTTTTTCCATTAGTGCAAAAAACCTGATGCAAGGGCAGCAAGATAAACACAATTTCTTCATTGACCCAGATAAGAACCTGTAGAAA
AGTGAGAGATGCCCCTAAGTTCCTATTTCATTTATCCTAAATAATATCCTGAATAACTACTGATCAGTTTTTTTCTATGTCCAGCCTTGC
TTCACTTTCCAACCTCCAGGCCAAATATTCATTTTGATATTTTACAAAATCCTTCTGGTTTTTACACAGGGCCCTTTTGTGCTGAGAATA
AAACCAGCTATTGGAACAGACCTCACTGCTTTGTAGAGTCAGAAGTTGACCTAGAGAATGGGTAGCAACAGGTCCTCAGTTTCTCTGGAG
ACACCCCCAATCCTTGGGTGAGTGTTGAAACCTGACAACTGACTGTTAGCCTTGTCATCATCCTCACTGGAGATGGAGATGTTGCAGTCG
GAGCCTCACTCCTTCTGGGGCACTGTTTCTTCTCATGGCAACCATTTTGCCTGCCTGGAAACAGCCTGTTGCCTTTGCTAGGGGGCAAAT
ACACACACTAGCCAAGGAAGTTGGTCCAGCACATCTCTGAGGTTTCTCCCCCATGGACCCATGGAGCGAATTCCCTGAGATAAATGATCA
GAAAGTTGGCTGTCTGGTGGTTTAATACTCCATAAGAGTTACTTCCCTTATAGAAAGTCATCCTTTGGCATCTAGATTTTTCTACAAATC
ACCTTAACTCCCTCCCTTTCTCTTTCTCCTGGAAAACCTCAGCATTGCATCTCCATGTTGCACAACACAGATCAGATTATCTGGTCACTA
TAGAGATTTGTATATAAAAAAACTACTTTTTTGAGGATTTTGTATATTGTTTTTCTATTTGTTTTCTACAGCTTGAGGAAAGAGCTGGCA
AACTGTGAATCTAACTTGATCTTGTTGCCAGCAGATATATTTTGGCTTCCTGGTAAGAGTCTGTGTTACCAGGGACAATATATTGCCCTC
TGATCAGTATTGCACCCTAAATCCACAAATTCCTCCAGCCCAGTCTTACATTTTTTTAAACAAATCCCCTAGCTTGTTTGCTATTATTTA
TAAAGAGCATTAGAAAATGTATTTATAGACCTGGATGTTATATGTTTAATATTAATTTAGCCTTTAATAATGTTATAGGTTTGTAACTAT
TCTTCAGAAATTATAAAGAACTCAGTGTAGACTGAATTAATCTATTTAGTATCTGTAATTTTGCAGACATATTTTCTTACAGTATTTTCT
ATGTAACCACACATGTAGAATTATAACTAATTAGAGCACAAGAAGTTTCTTCAGCAATTTAGAGCTACCAATTGTTTCTTGACTATATAG
TCACATTTGACAAATTTAAGAACCCAGTCTTTAGTGATGCAATAAACAAAATGAACCATTAAGAACAAGGAATTGCTTAAATCCCTTAGC
TGGTGAGGATATACATCTAAATAATTCATCTTTCTAACTCAAGGAATGGTGCTGATTTTTTAAATGTTTGACACCAGGCCTTGTTTTTCC
AGCTGAGCATTCTCATTTTGCTTTTCTCTAAGACTATCAAAGACAAGGTATTAATAGTAGGATTATTCCTAGATCAGAATGTTTCATACA
TTCCTAAAGGTTTATGTGGAAATTGGCTTAGGAAAACTTTGAGTAGCAGAGACTGAGGATGAGTGCTAGAGATGAAATCAGGACAGATTT
GTTGCAGTTAATTCTTGCCAAGCAAATTAGTGGTAAATGTCACATTGTTATGTGAATTGAGCACATATTTTTAAAGAAAGTTTACAAAAA
ATTTTTAGAACCAACTATGAGGCAATACTGTATCACTGGGGGCTGGGAGTGGGGGCTTAGAATCATACTGAAATTGTTTAAAAGCAGCCC
AGGTAGTTTCTGTCCTCAGGTGAATAACAGACTATATAACTTCCCCGAAAGGTAAAACGATAGCCACTGCAGAGACGAGGTGTCTTCCTT
CCACCAAATACTTTCTGAGATGGTGGTAGGAGTAGTATTTTTACCGTGGTTTAAAAAGTAGTCAGTTACATAGAAAGTGTATTGGTATGT
ATTTGAACCTGCTCTTCATTAAACAAACAGATTAGATGTACCCTCGACTGGCAATAATTGTATCTATTTTCAAGTACAGCTAGCTGTCAA
AGCATGAAGCTCTTGTGTATACACACTGACACTTGGTTCACGCATGAAGAACAGTGCCTATGCACTTTGTGTAGCTATAATGTAGGTATC
TAGGTGTAATTTCAGTGAAATGGTGTATAGATGTATTGTAATTTAAATGTATATGTTATTTTTGGCTATTCATCTAAATGCAGTAGACAT
GTTGATCGGTGTTTTGCAAACATTTCTTTTTCCTTCTTAGATAACTAGTCGTGAATCATTTCTCCTCTTTCTCAGTGTGGCTTGGGAATA
TATATGAGTGAAGAATTTATCTGTGAATCCTTTGTACTGATGATTGTTTGAAAGTCTGTGTGTGTCCAGCACCTTTGTAAATACACAATT
CAGAGCAGGGATGGGCTGGGTGTGTGTCCTGGTTCTTAGTGAAAGGTCATCTCATGTCTGTTTAATACATGGTGAATGCAACTGTGGAAC
TTTTGATTACCTAGACTTAGGTAGGTTTAGAATGAGAACATCCATCTACAGTCCTCCTTTGCTTGGTGGATTGGGCTCAGAGGAACAAAA
AGTTAGTCTGACTCTGTGCATATTAGCATCATGTCTTTAGAGAAAGGTCAGCCTCTCTGGTTGCCAAATACTCATCATGATGCTCATGAC
TTAAAGGTTCTGAGGAGCCTTGTCTCCCTTGGATTTTTGAGTCAGGGTACAGGAAAAAACATTGCTGACTAACTAACTGCAAATGCATCT
GCAGGTGAAACCCTACGAAAGCACAGTTCTGGCTATAAACTTCAGAGTTCTCTGTAAAAAACTTAGAGCACTAGAAGCACAGGAATAGTG
AGTGTACAGCTTATGCGGTTGTAGAGGGGCAACTGATGAACACAGGTCCCACATATATGAGGGAGTATGACGTTCTCTACCTAATATGTT
CTGTGTGCATGTTTTGAATGATTGAAGATGGGATTAACTAATGCAAGTTTACAGTTGCCTCCTAAAACACACATTCTGTATAATTATCGC
TAAATACAATGCTGTGAGGTCTATAGTTCCTGTAACCCCTTTCTCCTCCCCAAGGACAGAGAAGAACTAGCCATGTGCTATAGGGAACCC
TGAGTGCCCTACTCTTTTCCCAAGAAGGGTAAAGCCTACAATATCATCAGGGGGCATGAAGCACATTAATTTGCAGTGGCTGCTTCATAT
GAGGAGATATGGTGGACAGGCTAATTTTTCCTTGAAAATGTGGCTTCTTCAACTCCTTTCAAATTTAGGATGGAATACTTCCTGAAATAA
AACTGGGCTTTATGCAGGATTCTCTTTGAAAATTCTTGTATGTCCAGAACAAAAGATAAAACTAATTGTATTCCTCACATTCACAATCCC
CATTGGTCTGAAGTCACGTAGCACAGAGCATCTATAGCACATAGTGTTTAAAGACTAATGAATGCAAAAAGATAAAATCTTCAACTAATT
TTTGAATTGTTTCTCATATATGCTACTAGAAAATGCCTTGTTGATGAAGCACATTTTGGGTAGTTGAGGTCTTTTGTTTTCGCCTTTAGC
TTTCTAAGCTTTCTTACAATGTGGACTGATTACTGTAACATTTCACGTGTAAAATAACTGGATATTCTTTATATACTGGAAATAACCTGT

>In-frame_PAMR1_ENST00000378878_chr11_35461175_-_SLC1A2_ENST00000278379_chr11_35339063_-_12181nt
GCACCAGCCGCGGCAAGGATGGAGCTGGGTTGCTGGACGCAGTTGGGGCTCACTTTTCTTCAGCTCCTTCTCATCTCGTCCTTGCCAAGA
GAGTACACAGTCATTAATGAAGCCTGCCCTGGAGCAGAGTGGAATATCATGTGTCGGGAGTGCTGTGAATATGATCAGATTGAGTGCGTC
TGCCCCGGAAAGAGGGAAGTCGTGGGTTATACCATCCCTTGCTGCAGGAATGAGGAGAATGAGTGTGACTCCTGCCTGATCCACCCAGGT
TGTACCATCTTTGAAAACTGCAAGAGCTGCCGAAATGGCTCATGGGGGGGTACCTTGGATGACTTCTATGTGAAGGGGTTCTACTGTGCA
GAGTGCCGAGCAGGCTGGTACGGAGGAGACTGCATGCCATGCTCCTCATCCCCTTGTTTCCATGACGGCACGTGCGTCCTTGACAAGGCT
GGATCTTACAAGTGTGCCTGCTTGGCAGGCTATACTGGGCAGCGCTGTGAAAATCTCCTTGAAGAAAGAAACTGCTCAGACCCTGGGGGC
CCAGTCAATGGGTACCAGAAAATAACAGGGGGCCCTGGGCTTATCAACGGACGCCATGCTAAAATTGGCACCGTGGTGTCTTTCTTTTGT
AACAACTCCTATGTTCTTAGTGGCAATGAGAAAAGAACTTGCCAGCAGAATGGAGAGTGGTCAGGGAAACAGCCCATCTGCATAAAAGCC
TGCCGAGAACCAAAGATTTCAGACCTGGTGAGAAGGAGAGTTCTTCCGATGCAGGTTCAGTCAAGTGCCAACAATATGCCCAAGCAGGTG
GAAGTGCGAATGCACGACAGTCATCTTGGCTCAGAGGAACCCAAGCACCGGCACCTGGGCCTGCGCCTGTGTGACAAGCTGGGGAAGAAT
CTGCTGCTCACCCTGACGGTGTTTGGTGTCATCCTGGGAGCAGTGTGTGGAGGGCTTCTTCGCTTGGCATCTCCCATCCACCCTGATGTG
GTTATGTTAATAGCCTTCCCAGGGGATATACTCATGAGGATGCTAAAAATGCTCATTCTCCCTCTAATCATCTCCAGCTTAATCACAGGG
TTGTCAGGCCTGGATGCTAAGGCTAGTGGCCGCTTGGGCACGAGAGCCATGGTGTATTACATGTCCACGACCATCATTGCTGCAGTACTG
GGGGTCATTCTGGTCTTGGCTATCCATCCAGGCAATCCCAAGCTCAAGAAGCAGCTGGGGCCTGGGAAGAAGAATGATGAAGTGTCCAGC
CTGGATGCCTTCCTGGACCTTATTCGAAATCTCTTCCCTGAAAACCTTGTCCAAGCCTGCTTTCAACAGATTCAAACAGTGACGAAGAAA
GTCCTGGTTGCACCACCGCCGGACGAGGAGGCCAACGCAACCAGCGCTGTTGTCTCTCTGTTGAACGAGACTGTGACTGAGGTGCCGGAG
GAGACTAAGATGGTTATCAAGAAGGGCCTGGAGTTCAAGGATGGGATGAACGTCTTAGGTCTGATAGGGTTTTTCATTGCTTTTGGCATC
GCTATGGGGAAGATGGGAGATCAGGCCAAGCTGATGGTGGATTTCTTCAACATTTTGAATGAGATTGTAATGAAGTTAGTGATCATGATC
ATGTGGTACTCTCCCCTGGGTATCGCCTGCCTGATCTGTGGAAAGATCATTGCAATCAAGGACTTAGAAGTGGTTGCTAGGCAACTGGGG
ATGTACATGGTAACAGTGATCATAGGCCTCATCATCCACGGGGGCATCTTTCTCCCCTTGATTTACTTTGTAGTGACCAGGAAAAACCCC
TTCTCCTTTTTTGCTGGCATTTTCCAAGCTTGGATCACTGCCCTGGGCACCGCTTCCAGTGCTGGAACTTTGCCTGTCACCTTTCGTTGC
CTGGAAGAAAATCTGGGGATTGATAAGCGTGTGACTAGATTCGTCCTTCCTGTTGGAGCAACCATTAACATGGATGGTACAGCCCTTTAT
GAAGCGGTAGCCGCCATCTTTATAGCCCAAATGAATGGTGTTGTCCTGGATGGAGGACAGATTGTGACTGTAAGCCTCACAGCCACCCTG
GCAAGCGTCGGCGCGGCCAGTATCCCCAGTGCCGGGCTGGTCACCATGCTCCTCATTCTGACAGCCGTGGGCCTGCCAACAGAGGACATC
AGCCTGCTGGTGGCTGTGGACTGGCTGCTGGACAGGATGAGAACTTCAGTCAATGTTGTGGGTGACTCTTTTGGGGCTGGGATAGTCTAT
CACCTCTCCAAGTCTGAGCTGGATACCATTGACTCCCAGCATCGAGTGCATGAAGATATTGAAATGACCAAGACTCAATCCATTTATGAT
GACATGAAGAACCACAGGGAAAGCAACTCTAATCAATGTGTCTATGCTGCACACAACTCTGTCATAGTAGATGAATGCAAGGTAACTCTG
GCAGCCAATGGAAAGTCAGCCGACTGCAGTGTTGAGGAAGAACCTTGGAAACGTGAGAAATAAGGATATGAGTCTCAGCAAATTCTTGAA
TAAACTCCCCAGCGTATCCTATGGTAACTGATGATATAAACAAGCTTTCTTTAAAAAGGAAAAAAATGCGTATATTTCTATGTTTACTTA
ATCTGTTAGCCGAGGCTTAGAGGAGCTCTTGTGAGTCAGTGATGACAGGCACGGTGCTGTGTCTTTGCCAAATAATGCTTTATAACCGTC
TAATTTTCTCACTTGTATTATTATTTGAATGGATGCTGCTGGAGGAATCAGTTGGAATTGAAGACACGTTCTTGCCAGCTTCCCTTTTCT
CCCAAGATGCAGAAATGTGGATGCTCTTTTCCCAGGGGACATGAGTAAAGCAGTGTGGTACACTCCAGGGACTTGGGAAAATGAGCAAAC
ACACAGCGTGTTATTCCTTAAAGTGTTCTCCATGTCTCGCCTTGTTATGCACAAGAGATTCTATTAAAAGCCTCTAGAAGTAACTCCCCT
TAAAATGTCTAGTAAAGCTTGCACATGGATTGATTAAAAGCAAATACCTGTCTTAGGGAATTCTGACAATTTATCTTCCATATGCTCTTT
AAGTAAAATGTTTCAAAGACAGTTTTAAAGGGAGCCATGCTCTTAAAGGCAGTTGATTAAAGAACCTGTTACATCTCTGCCTTACCCTGT
GTAATCTGTGAGAACAATGGTTGAAATTTCAAAGTATGTTTCATTATTCTTTCTAAATTTGATAATTGATTAGGAAGTATTTTATATATA
ACCACTGTAGATATTGACAAAAGTAAGAGAGCACAGTCAACATAAAGTTTAACCAGAGTTAAATATTCAAATTTATTTATGTTCGGTTTG
CCTTCACCTGGTGTAGTAAAATCAAATGAGATTATTTGGTATGTGTTTTGCTTTGTTTAACCCAAAAGATTATTTTTTGGTTCCTAAAGA
AAAAGATATTTTTAATCTGTCAATTATTTCAGTCATCATCTCATCGTCCTAGAAAGCCTGGTCATTTTACTGTCCTCACACATGGAAGAC
ACTTGTGTTGGCTGTGCCTCTTTTAATGTCATCTCTTGATGAAACAAAAATACTGGTATTTATCCAATATGTTGAAAGCGTTTTGTTATC
TTCTATCAAAGCACATAAAACCAGTTATAGGACACAGTTGGAAGCAGAGCCAGTCTTCCTCCTCAGTCTTCTCAGTAGAAAGGAACAGAA
AACAAACATCTGTGCAAAACCCTATAAAAGTGATATTCCTATGGCAGAGTCCAGGCAGCCTTGAACAATGACATGGCAACAAAGGATGGC
TCTGTACAACTTCACAGATGGAATCTTGTTTAAGGCTGTGAAGTTTTAAGGAATAAATAATATAATTGGTGTAGCACAGTGCCTTGCATG
CAGTAGGCAGCCAACAAATCCTTAATGATTGGTAATGCAAGCTAAAATTTTTAATGTCTCTACTATCCTTTTTTATTGAATAACGCACAG
TATTTTCCTAAGGTTGCTGGGTTTGGGAGTAAGCTTGGGACTTGAATCATTGAGAAATAAAGCACATTTGACTCTAAGAAGTATGTAGAA
CCTTGTTTATAGGTGAGAATAGGCTGTATTATATGAAACCAGCGGAGGGATGCTGAGACAGTCATGGTTTATAGAATCCAAATTCTCTGA
GATGAGGGTGCTTATGGACCTCAAATAGCCTTTCTTATCTGCTCCTTGTGACTTCTCTCTTTTAAATCAGATACCTTTGAAACATACAAG
AGACATGAGATTCCAGTTGTTTTTGTCTCCTAAACCCTAGTGATTTTTGGATAAGGATCACTACTGAACAGTATTAGGCAACTTTTCATT
TTTGCTTTTCAAATGACATTGGTCTTTATTTCCAGTAGATGGGCAGTAAACAGGGTCAGGGTGGTCAAGGGATATGATTAAGTGTAGTAG
TAGAAAATGCATTCTTTTTTTTTTTTTTTTTTTAGACAGAGTCTTGCTCTGTTGCTCAGGCTGGAGTACAGTGGCACGATCTCAGCTCAC
TGCACTGCAATGTCCACCTCTCTAGTTCAAGCGATTCTCCTGTCTCAGCCTCCCGAGTAGCTGGGACTACAGGCACATGCCACCATGCCT
GGCTAATTTTTTGTATTTTTAGTACAGATGGGTTTCATTATGTTAGCCAGGATGGTCTCGATCTCCTGACCTCATGATCCACCCGCCATG
GCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGTGCCCGGCCAGAAAATACATTCTTTACAGCAAATGTTATAGGTTAAGGAGAC
AGTTCCTGGGTTTAGCTGTGAAACTGTTTAGGATTTTCTTTAAGTGGTGTTCCCAAGAGCTTTTTTCTGGTAAGTTGGAGGCTATAGGCA
AAGCGTCTAGGAGCTTGTTGTTTTTTGCTATGGAAGGCCAGCTTTGGGATCTATATACATGGGCATGTTTCTCAATGGAGTGGTCACAGG
ATTCTCTTCTCAGAACTCTGCCTGAAACCTTTCCGGTGTGTTTTGTCTTCAACTTTTTCCTAGCTATCCTATTAGCCTGTAAATATGTCA
GCAGACAATGTGTTTGGAAGAAACAAGGTGTACAACTTCACAAAGCAAGTTTTTTCTGGTCTGAGACTTACTGTGTGCAGGAAGTCTCGT
GAGAATATACTTAGAAAATCACACTTATCTGGAAATTCAATAAGTCATATTAAAAATATACAATTTCTTGAACTCAGGACTAGCCTGAAA
ATCCAAAATGCATGTAGAGTTGACATGTTGACATATGTCTATGTCCTCTGTTTTTATTTAAGCCTCATTTATTTCTCCCTTGCCATGCCC
ATTTGGGATTTTCTTTGCCCAGCATATGTGCCATAAACAGAACAAATGGATCCAGGGTATACCTCTAATAACCTTTATCTAAATAGAATA
CATTTAACCTGTCAATTATATGTATAGATTTATCCTAATTGGTTCAACATATATATGAATGCTTGTAATAGTCTGTTACTATTTGATAAT
GCATAAATGTTATATTTATATACAGTTACAGCAGGCCAGAAACATACATACACTGCATCCTGTAAGGTCTGTAAATCAGGGCTTCGGCAA
TGCCATTTTGCTATAGACTCATTCATGTTTTTTAGGAATCAGAATCATTTCAGGAGAAAACCAACTAAGTAGACTTTAATTCTTCTCTTT
CTCATTCTTGCCCTTTGAGAAACCCAAGTGGAATCATCACTTAATTACTTACTCAAATTCAATGAATCAAATCCAATCCAATCAGTGAGA
AGAATAGCTTATCTTTCAAGGTAATACTTTACCTTAGATCTTTGAGGGCATGCTTCCCATACAAAGAGCATCAGAAAATCAGGGCAATCA
TCTAGATCTCACAGATCTTCAACATAGGACTCTAGGTTATGAGAGCTGAACCACATAGCTATCAGTTTCAGTTTTTACTTCCTATTGAGT
GTGTAGAAACACAGCCTATGGTTTTGCTGTCTGCGGAAGTTACCATACCCTGTAAAAGACAAATATTTCTTTCTCCTCTCGAACCACTAG
TCAGCCTGGATATTCATGAAAGCTGAAAGAAGGGGTGCCAAAATGCCTAGCTCCTGGATTTAGACTCATGGAATATGAGAAAGGCTTAGG
GAAAATTCAAGTCATGGGGAGATTCCTGCTAGGTGATGCCAGGAATCTCAATGACCTGTTGATTAGAGGGTCTCTGGTCATTTCCACTTG
TGTGTGGAGAAATACATCATTTGCATATGTATCTAGTCAAGAAGCCCTTTTGGAGCAAAGTGGTTGGGAAACTCATTTACTGGGTCCACC
AAAGGAAACCCAATTCTGCCATGTTTTTGCAAATACTACACGTCCCTTTGCTCTCAATAGCAAAAGTGATGTTATAGTTTTTTTTACTTT
TGTCAGAATCAAGGCTTCGGCCACCTGTGCAATATTTTCCCATGGAATGCAGCAGTAAATCCAAGTAGGTATATCCGTGCTCAGAGAGAA
TTCTCCATAGTTCTGACTCCTGAAAAACAAGTCTCATTAGCTCTCATCTAGTTTGATGACTAAAAGTGCACAGCAGTTATACCCCAGTGG
AAGTGATTTTTCTCACCTAGCTGCTCTCTAACTCTTACGGCTATCTAGTTGTCTGAGCTGCTGGTTTGTTTTACTTATTCTCCAACTGAA
CTCATTCCAAACCAAGAAAAAGGACCAAATGAAATTTTCAGTTATTATCATACTTGCTCCTTGAATAAGAATGCTAGAGTCTGGAGGCAG
AAGAAGACTAAGTTAAAAAAAAAACAGCCTGAAGGAATTCTGGAGTGAGTTTTGTAAGTCTAATTGTCAAAGAAGATAAATGGTCTCAGT
ATCTGTAGTAATTTCTGGTTAAGCCTAGAGGGATCACTGAGTGCCAATCCAAGCAGGTGGCACTAGAGGCAGATTGTTCTCCTAGCATAG
AGTGAGTTTCCAGCTGCTCATGACACATTTTCTTATGATTTTCCCTAAAAGAAAACCAAATTTTCTACTCCACCTCTTCCTTTCCTATCA
TTCCACTTATTGTTGCTGCTTTGCTAACAGCCAGCTTAGTAAGCCATCACACAAGTTAGTGTGAGGCTTGGTTTTAAAATAGATAACAGA
GAATCTTGATTAAATAGTATCCAACTTTGTAGCATAACACAGCTAATTCAGGCAATGACATAGAGATGATAAGAAACAACATGGTTTGGT
AGAGGGAACATTTGATTTAGACTCTGCCCATTTTTAGCTGTATGACTTACATAAGTCATTTTGTGTCCAAGCCTCATTTTCTCCCATATG
AAAAGTGAAGGGGTTGGATTAAATGACTAAAATCCCCTTCCAGCCCTATGAGCCCAATGTATTATGATCTCTGCTTTGTTTCCTTCTTAA
GAGGCTTCCTACTATAAAATGTGACCTATTTACATTTTAAGTTGAAGTAGCCCACAATAATGAATAATCAATTTAGATTTTTCTCATCTC
CTTTGGGAGAAATTAAATTCAAGCCTCTATTCATTTGATGTTTTACAACAAGCTTCAAAGTTGGCCATGTTCATTCACAGTTTGATATTT
TGAGACACCAATAAAAGTTTTTTAATAAAAGTTCCCTTGACTTAAACTCACCTTCCTAATAGAAGTAGTGATTTGGCTCACGGAAAAATG
TTTCCAGAGTCAACATGAGAGGACTGGATGAACCTACAGCCTCACTCAAGCTGTTGCATCATTGCTGCTGTAGCAACAGAGCCCTCTCTG
AATACCCAAAACACACAATTTTCTCCAACAATTCTAATTGCCCACCCAGTATGGGAATTTGAGAGCCTTTGGTGAATAACCTTGATCACT
CTTTTGAAATTTGGTACAACACTTGCACAATCACGGCAACTGTTTGTAAATATCTTTTCTTCTCCGCCAGTATGTAGACATGCACACCCA
TTCACAAGTAAGCCCGCAAATTCATTTTCACATTTTCCTCTTGGTTTGTTTTTATCATGGGTATCACATTGCAGGAAGAGATGCTCTAAC
TTACAAGAATGGAATTTTCTGACTATCATTGCCCTCTTCAAGGCCTGATTAGTTTGTAGGGTGGATGGGATACAATGCATGGTCTACAAG
GTCCATGTCACCAGCCATGATCTTTAAACAACCTCTTGCACTTTCTGGCACTGCTGCAATGGCCCATGGTGGACACCTCTGCTGTTTGTC
CAAACTTCTGCTAAATAGAGTAGTGTTGGTATTTGTTGTGTTGTGAACTCCTTTGTTGTCAGAGAAGACTTCAGCTCTTCAGGTTTGCAA
GGGCAAGATGTAAAGCTAGGACTGAAAGGATTGGGTTTTGTTTTTCGGCCGGCTTTTTTCCATTAGTGCAAAAAACCTGATGCAAGGGCA
GCAAGATAAACACAATTTCTTCATTGACCCAGATAAGAACCTGTAGAAAAGTGAGAGATGCCCCTAAGTTCCTATTTCATTTATCCTAAA
TAATATCCTGAATAACTACTGATCAGTTTTTTTCTATGTCCAGCCTTGCTTCACTTTCCAACCTCCAGGCCAAATATTCATTTTGATATT
TTACAAAATCCTTCTGGTTTTTACACAGGGCCCTTTTGTGCTGAGAATAAAACCAGCTATTGGAACAGACCTCACTGCTTTGTAGAGTCA
GAAGTTGACCTAGAGAATGGGTAGCAACAGGTCCTCAGTTTCTCTGGAGACACCCCCAATCCTTGGGTGAGTGTTGAAACCTGACAACTG
ACTGTTAGCCTTGTCATCATCCTCACTGGAGATGGAGATGTTGCAGTCGGAGCCTCACTCCTTCTGGGGCACTGTTTCTTCTCATGGCAA
CCATTTTGCCTGCCTGGAAACAGCCTGTTGCCTTTGCTAGGGGGCAAATACACACACTAGCCAAGGAAGTTGGTCCAGCACATCTCTGAG
GTTTCTCCCCCATGGACCCATGGAGCGAATTCCCTGAGATAAATGATCAGAAAGTTGGCTGTCTGGTGGTTTAATACTCCATAAGAGTTA
CTTCCCTTATAGAAAGTCATCCTTTGGCATCTAGATTTTTCTACAAATCACCTTAACTCCCTCCCTTTCTCTTTCTCCTGGAAAACCTCA
GCATTGCATCTCCATGTTGCACAACACAGATCAGATTATCTGGTCACTATAGAGATTTGTATATAAAAAAACTACTTTTTTGAGGATTTT
GTATATTGTTTTTCTATTTGTTTTCTACAGCTTGAGGAAAGAGCTGGCAAACTGTGAATCTAACTTGATCTTGTTGCCAGCAGATATATT
TTGGCTTCCTGGTAAGAGTCTGTGTTACCAGGGACAATATATTGCCCTCTGATCAGTATTGCACCCTAAATCCACAAATTCCTCCAGCCC
AGTCTTACATTTTTTTAAACAAATCCCCTAGCTTGTTTGCTATTATTTATAAAGAGCATTAGAAAATGTATTTATAGACCTGGATGTTAT
ATGTTTAATATTAATTTAGCCTTTAATAATGTTATAGGTTTGTAACTATTCTTCAGAAATTATAAAGAACTCAGTGTAGACTGAATTAAT
CTATTTAGTATCTGTAATTTTGCAGACATATTTTCTTACAGTATTTTCTATGTAACCACACATGTAGAATTATAACTAATTAGAGCACAA
GAAGTTTCTTCAGCAATTTAGAGCTACCAATTGTTTCTTGACTATATAGTCACATTTGACAAATTTAAGAACCCAGTCTTTAGTGATGCA
ATAAACAAAATGAACCATTAAGAACAAGGAATTGCTTAAATCCCTTAGCTGGTGAGGATATACATCTAAATAATTCATCTTTCTAACTCA
AGGAATGGTGCTGATTTTTTAAATGTTTGACACCAGGCCTTGTTTTTCCAGCTGAGCATTCTCATTTTGCTTTTCTCTAAGACTATCAAA
GACAAGGTATTAATAGTAGGATTATTCCTAGATCAGAATGTTTCATACATTCCTAAAGGTTTATGTGGAAATTGGCTTAGGAAAACTTTG
AGTAGCAGAGACTGAGGATGAGTGCTAGAGATGAAATCAGGACAGATTTGTTGCAGTTAATTCTTGCCAAGCAAATTAGTGGTAAATGTC
ACATTGTTATGTGAATTGAGCACATATTTTTAAAGAAAGTTTACAAAAAATTTTTAGAACCAACTATGAGGCAATACTGTATCACTGGGG
GCTGGGAGTGGGGGCTTAGAATCATACTGAAATTGTTTAAAAGCAGCCCAGGTAGTTTCTGTCCTCAGGTGAATAACAGACTATATAACT
TCCCCGAAAGGTAAAACGATAGCCACTGCAGAGACGAGGTGTCTTCCTTCCACCAAATACTTTCTGAGATGGTGGTAGGAGTAGTATTTT
TACCGTGGTTTAAAAAGTAGTCAGTTACATAGAAAGTGTATTGGTATGTATTTGAACCTGCTCTTCATTAAACAAACAGATTAGATGTAC
CCTCGACTGGCAATAATTGTATCTATTTTCAAGTACAGCTAGCTGTCAAAGCATGAAGCTCTTGTGTATACACACTGACACTTGGTTCAC
GCATGAAGAACAGTGCCTATGCACTTTGTGTAGCTATAATGTAGGTATCTAGGTGTAATTTCAGTGAAATGGTGTATAGATGTATTGTAA
TTTAAATGTATATGTTATTTTTGGCTATTCATCTAAATGCAGTAGACATGTTGATCGGTGTTTTGCAAACATTTCTTTTTCCTTCTTAGA
TAACTAGTCGTGAATCATTTCTCCTCTTTCTCAGTGTGGCTTGGGAATATATATGAGTGAAGAATTTATCTGTGAATCCTTTGTACTGAT
GATTGTTTGAAAGTCTGTGTGTGTCCAGCACCTTTGTAAATACACAATTCAGAGCAGGGATGGGCTGGGTGTGTGTCCTGGTTCTTAGTG
AAAGGTCATCTCATGTCTGTTTAATACATGGTGAATGCAACTGTGGAACTTTTGATTACCTAGACTTAGGTAGGTTTAGAATGAGAACAT
CCATCTACAGTCCTCCTTTGCTTGGTGGATTGGGCTCAGAGGAACAAAAAGTTAGTCTGACTCTGTGCATATTAGCATCATGTCTTTAGA
GAAAGGTCAGCCTCTCTGGTTGCCAAATACTCATCATGATGCTCATGACTTAAAGGTTCTGAGGAGCCTTGTCTCCCTTGGATTTTTGAG
TCAGGGTACAGGAAAAAACATTGCTGACTAACTAACTGCAAATGCATCTGCAGGTGAAACCCTACGAAAGCACAGTTCTGGCTATAAACT
TCAGAGTTCTCTGTAAAAAACTTAGAGCACTAGAAGCACAGGAATAGTGAGTGTACAGCTTATGCGGTTGTAGAGGGGCAACTGATGAAC
ACAGGTCCCACATATATGAGGGAGTATGACGTTCTCTACCTAATATGTTCTGTGTGCATGTTTTGAATGATTGAAGATGGGATTAACTAA
TGCAAGTTTACAGTTGCCTCCTAAAACACACATTCTGTATAATTATCGCTAAATACAATGCTGTGAGGTCTATAGTTCCTGTAACCCCTT
TCTCCTCCCCAAGGACAGAGAAGAACTAGCCATGTGCTATAGGGAACCCTGAGTGCCCTACTCTTTTCCCAAGAAGGGTAAAGCCTACAA
TATCATCAGGGGGCATGAAGCACATTAATTTGCAGTGGCTGCTTCATATGAGGAGATATGGTGGACAGGCTAATTTTTCCTTGAAAATGT
GGCTTCTTCAACTCCTTTCAAATTTAGGATGGAATACTTCCTGAAATAAAACTGGGCTTTATGCAGGATTCTCTTTGAAAATTCTTGTAT
GTCCAGAACAAAAGATAAAACTAATTGTATTCCTCACATTCACAATCCCCATTGGTCTGAAGTCACGTAGCACAGAGCATCTATAGCACA
TAGTGTTTAAAGACTAATGAATGCAAAAAGATAAAATCTTCAACTAATTTTTGAATTGTTTCTCATATATGCTACTAGAAAATGCCTTGT
TGATGAAGCACATTTTGGGTAGTTGAGGTCTTTTGTTTTCGCCTTTAGCTTTCTAAGCTTTCTTACAATGTGGACTGATTACTGTAACAT
TTCACGTGTAAAATAACTGGATATTCTTTATATACTGGAAATAACCTGTGAATCCAATATTTCACTAAGTGTTTTAACTTTTGTGTATAT


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FusionGenePPI for PAMR1_SLC1A2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
PAMR1SLC1A2AJUBA, GRB2, PML, MAPT, RPL17, RPL23A, RPL32, RPL38, RPL5, RPL3


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for PAMR1_SLC1A2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
TgeneSLC1A2P43004DB00142Glutamic AcidExcitatory amino acid transporter 2small moleculeapproved|nutraceutical

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RelatedDiseases for PAMR1_SLC1A2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgenePAMR1C0023893Liver Cirrhosis, Experimental1CTD_human
TgeneSLC1A2C0005586Bipolar Disorder4PSYGENET
TgeneSLC1A2C0036341Schizophrenia4PSYGENET
TgeneSLC1A2C0001973Alcoholic Intoxication, Chronic3PSYGENET
TgeneSLC1A2C0011570Mental Depression3PSYGENET
TgeneSLC1A2C0011581Depressive disorder3PSYGENET
TgeneSLC1A2C0002736Amyotrophic Lateral Sclerosis1CTD_human
TgeneSLC1A2C0014544Epilepsy1CTD_human
TgeneSLC1A2C0027746Nerve Degeneration1CTD_human
TgeneSLC1A2C0038356Stomach Neoplasms1CTD_human
TgeneSLC1A2C0236736Cocaine-Related Disorders1CTD_human
TgeneSLC1A2C0525045Mood Disorders1PSYGENET