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Fusion gene ID: 25851 |
FusionGeneSummary for PALLD_ANXA10 |
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Fusion gene information | Fusion gene name: PALLD_ANXA10 | Fusion gene ID: 25851 | Hgene | Tgene | Gene symbol | PALLD | ANXA10 | Gene ID | 23022 | 11199 |
Gene name | palladin, cytoskeletal associated protein | annexin A10 | |
Synonyms | CGI-151|CGI151|MYN|PNCA1|SIH002 | ANX14 | |
Cytomap | 4q32.3 | 4q32.3 | |
Type of gene | protein-coding | protein-coding | |
Description | palladinmyoneurinsarcoma antigen NY-SAR-77 | annexin A10annexin 14annexin-10 | |
Modification date | 20180523 | 20180519 | |
UniProtAcc | Q8WX93 | Q9UJ72 | |
Ensembl transtripts involved in fusion gene | ENST00000335742, ENST00000261509, ENST00000505667, ENST00000333488, ENST00000512127, ENST00000507735, | ENST00000359299, | |
Fusion gene scores | * DoF score | 8 X 7 X 4=224 | 3 X 2 X 3=18 |
# samples | 8 | 3 | |
** MAII score | log2(8/224*10)=-1.48542682717024 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
Context | PubMed: PALLD [Title/Abstract] AND ANXA10 [Title/Abstract] AND fusion [Title/Abstract] | ||
Functional or gene categories assigned by FusionGDB annotation |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
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Partner | Gene | GO ID | GO term | PubMed ID |
![]() (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
TCGA | RV | SARC | TCGA-DX-A8BJ-01A | PALLD | chr4 | 169553051 | + | ANXA10 | chr4 | 169083679 | + |
* LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
intron-3CDS | ENST00000335742 | ENST00000359299 | PALLD | chr4 | 169553051 | + | ANXA10 | chr4 | 169083679 | + |
intron-3CDS | ENST00000261509 | ENST00000359299 | PALLD | chr4 | 169553051 | + | ANXA10 | chr4 | 169083679 | + |
intron-3CDS | ENST00000505667 | ENST00000359299 | PALLD | chr4 | 169553051 | + | ANXA10 | chr4 | 169083679 | + |
intron-3CDS | ENST00000333488 | ENST00000359299 | PALLD | chr4 | 169553051 | + | ANXA10 | chr4 | 169083679 | + |
5UTR-3CDS | ENST00000512127 | ENST00000359299 | PALLD | chr4 | 169553051 | + | ANXA10 | chr4 | 169083679 | + |
intron-3CDS | ENST00000507735 | ENST00000359299 | PALLD | chr4 | 169553051 | + | ANXA10 | chr4 | 169083679 | + |
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FusionProtFeatures for PALLD_ANXA10 |
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Hgene | Tgene |
PALLD | ANXA10 |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for PALLD_ANXA10 |
![]() (nt: nucleotides, aa: amino acids) |
* Fusion amino acid sequences. |
* Fusion transcript sequences (only coding sequence (CDS) region). |
* Fusion transcript sequences (Full-length transcript). |
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FusionGenePPI for PALLD_ANXA10 |
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Hgene | Hgene's interactors | Tgene | Tgene's interactors |
PALLD | EZR, ISG15, SORBS2, ACTN1, ACOX1, SARS, HSP90AA4P, IGBP1, DSTN, HSPB1, NDUFV1, LIG4, SIRT6, GRPEL1, WDFY2, TSG101, NTRK1, SRPK2, CEP162, CEP152, CNTROB, CEP128, NINL, NIN, ODF2, SCLT1, CEP83, CENPJ, FLNA, HSPA5, KDR, LLGL2, MYH9, MYO1C, PDLIM7, MYO19, SKA3, MCM2, NCKIPSD, PFN2, BCHE, TRIM25, G3BP1, BRCA1, TES | ANXA10 | BAG3, EDC3 |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for PALLD_ANXA10 |
![]() (DrugBank Version 5.1.0 2018-04-02) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for PALLD_ANXA10 |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Hgene | PALLD | C0043094 | Weight Gain | 1 | CTD_human |