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Fusion gene ID: 25716 |
FusionGeneSummary for PABPC1_KHDRBS3 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PABPC1_KHDRBS3 | Fusion gene ID: 25716 | Hgene | Tgene | Gene symbol | PABPC1 | KHDRBS3 | Gene ID | 26986 | 10656 |
| Gene name | poly(A) binding protein cytoplasmic 1 | KH RNA binding domain containing, signal transduction associated 3 | |
| Synonyms | PAB1|PABP|PABP1|PABPC2|PABPL1 | Etle|SALP|SLM-2|SLM2|T-STAR|TSTAR|etoile | |
| Cytomap | 8q22.3 | 8q24.23 | |
| Type of gene | protein-coding | protein-coding | |
| Description | polyadenylate-binding protein 1poly(A) binding protein, cytoplasmic 2 | KH domain-containing, RNA-binding, signal transduction-associated protein 3KH domain containing, RNA binding, signal transduction associated 3RNA-binding protein T-StarSam68-like phosphotyrosine protein, T-STARsam68-like mammalian protein 2 | |
| Modification date | 20180523 | 20180522 | |
| UniProtAcc | P11940 | O75525 | |
| Ensembl transtripts involved in fusion gene | ENST00000318607, ENST00000519004, ENST00000522387, ENST00000519596, | ENST00000355849, ENST00000520981, ENST00000522578, | |
| Fusion gene scores | * DoF score | 11 X 10 X 5=550 | 11 X 6 X 9=594 |
| # samples | 12 | 11 | |
| ** MAII score | log2(12/550*10)=-2.1963972128035 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(11/594*10)=-2.43295940727611 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: PABPC1 [Title/Abstract] AND KHDRBS3 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | PABPC1 | GO:2000623 | negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 18447585 |
| Tgene | KHDRBS3 | GO:0051259 | protein complex oligomerization | 10332027|10749975 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | LGG | TCGA-DH-A66G-01A | PABPC1 | chr8 | 101724880 | - | KHDRBS3 | chr8 | 136554897 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000318607 | ENST00000355849 | PABPC1 | chr8 | 101724880 | - | KHDRBS3 | chr8 | 136554897 | + |
| 5CDS-intron | ENST00000318607 | ENST00000520981 | PABPC1 | chr8 | 101724880 | - | KHDRBS3 | chr8 | 136554897 | + |
| 5CDS-intron | ENST00000318607 | ENST00000522578 | PABPC1 | chr8 | 101724880 | - | KHDRBS3 | chr8 | 136554897 | + |
| In-frame | ENST00000519004 | ENST00000355849 | PABPC1 | chr8 | 101724880 | - | KHDRBS3 | chr8 | 136554897 | + |
| 5CDS-intron | ENST00000519004 | ENST00000520981 | PABPC1 | chr8 | 101724880 | - | KHDRBS3 | chr8 | 136554897 | + |
| 5CDS-intron | ENST00000519004 | ENST00000522578 | PABPC1 | chr8 | 101724880 | - | KHDRBS3 | chr8 | 136554897 | + |
| In-frame | ENST00000522387 | ENST00000355849 | PABPC1 | chr8 | 101724880 | - | KHDRBS3 | chr8 | 136554897 | + |
| 5CDS-intron | ENST00000522387 | ENST00000520981 | PABPC1 | chr8 | 101724880 | - | KHDRBS3 | chr8 | 136554897 | + |
| 5CDS-intron | ENST00000522387 | ENST00000522578 | PABPC1 | chr8 | 101724880 | - | KHDRBS3 | chr8 | 136554897 | + |
| 5UTR-3CDS | ENST00000519596 | ENST00000355849 | PABPC1 | chr8 | 101724880 | - | KHDRBS3 | chr8 | 136554897 | + |
| 5UTR-intron | ENST00000519596 | ENST00000520981 | PABPC1 | chr8 | 101724880 | - | KHDRBS3 | chr8 | 136554897 | + |
| 5UTR-intron | ENST00000519596 | ENST00000522578 | PABPC1 | chr8 | 101724880 | - | KHDRBS3 | chr8 | 136554897 | + |
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FusionProtFeatures for PABPC1_KHDRBS3 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| PABPC1 | KHDRBS3 |
| Binds the poly(A) tail of mRNA, including that of itsown transcript. May be involved in cytoplasmic regulatoryprocesses of mRNA metabolism such as pre-mRNA splicing. Itsfunction in translational initiation regulation can either beenhanced by PAIP1 or repressed by PAIP2. Can probably bind tocytoplasmic RNA sequences other than poly(A) in vivo. Involved intranslationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translationaland decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. Involved inregulation of nonsense-mediated decay (NMD) of mRNAs containingpremature stop codons; for the recognition of prematuretermination codons (PTC) and initiation of NMD a competitiveinteraction between UPF1 and PABPC1 with the ribosome-boundrelease factors is proposed. By binding to long poly(A) tails, mayprotect them from uridylation by ZCCHC6/ZCCHC11 and hencecontribute to mRNA stability (PubMed:25480299). Positivelyregulates the replication of dengue virus (DENV)(PubMed:26735137). {ECO:0000269|PubMed:11051545,ECO:0000269|PubMed:17212783, ECO:0000269|PubMed:18447585,ECO:0000269|PubMed:20573744, ECO:0000269|PubMed:25480299,ECO:0000269|PubMed:26735137}. | RNA-binding protein that plays a role in the regulationof alternative splicing and influences mRNA splice site selectionand exon inclusion. Binds preferentially to the 5'-[AU]UAAA-3'motif in vitro. Binds optimally to RNA containing 5'-[AU]UAA-3' asa bipartite motif spaced by more than 15 nucleotides. Bindspoly(A). RNA-binding abilities are down-regulated by tyrosinekinase PTK6 (PubMed:10564820, PubMed:19561594, PubMed:26758068).Involved in splice site selection of vascular endothelial growthfactor (PubMed:15901763). In vitro regulates CD44 alternativesplicing by direct binding to purine-rich exonic enhancer (Bysimilarity). Can regulate alternative splicing of neurexins NRXN1-3 in the laminin G-like domain 6 containing the evolutionaryconserved neurexin alternative spliced segment 4 (AS4) involved inneurexin selective targeting to postsynaptic partners such asneuroligins and LRRTM family members (PubMed:26758068). Targeted,cell-type specific splicing regulation of NRXN1 at AS4 is involvedin neuronal glutamatergic synapse function and plasticity (Bysimilarity). May regulate expression of KHDRBS2/SLIM-1 in definedbrain neuron populations by modifying its alternative splicing (Bysimilarity). Can bind FABP9 mRNA (By similarity). May play a roleas a negative regulator of cell growth. Inhibits cellproliferation. {ECO:0000250|UniProtKB:Q9JLP1,ECO:0000250|UniProtKB:Q9R226, ECO:0000269|PubMed:10564820,ECO:0000269|PubMed:15901763, ECO:0000269|PubMed:19561594,ECO:0000269|PubMed:26758068}. (Microbial infection) Involved in post-transcriptionalregulation of HIV-1 gene expression.{ECO:0000269|PubMed:11741900}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | PABPC1 | chr8:101724880 | chr8:136554897 | ENST00000318607 | - | 6 | 15 | 11_89 | 292 | 311 | Domain | RRM 1 |
| Hgene | PABPC1 | chr8:101724880 | chr8:136554897 | ENST00000318607 | - | 6 | 15 | 191_268 | 292 | 311 | Domain | RRM 3 |
| Hgene | PABPC1 | chr8:101724880 | chr8:136554897 | ENST00000318607 | - | 6 | 15 | 99_175 | 292 | 311 | Domain | RRM 2 |
| Hgene | PABPC1 | chr8:101724880 | chr8:136554897 | ENST00000318607 | - | 6 | 15 | 166_289 | 292 | 311 | Region | Note=CSDE1-binding |
| Tgene | >KHDRBS3 | chr8:101724880 | chr8:136554897 | ENST00000355849 | + | 1 | 9 | 250_261 | 69 | 347 | Compositional bias | Note=Pro-rich |
| Tgene | >KHDRBS3 | chr8:101724880 | chr8:136554897 | ENST00000355849 | + | 1 | 9 | 266_316 | 69 | 347 | Compositional bias | Note=Tyr-rich |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >PABPC1 | chr8:101724880 | chr8:136554897 | ENST00000318607 | - | 6 | 15 | 495_501 | 292 | 311 | Compositional bias | Note=Poly-Ala |
| Hgene | >PABPC1 | chr8:101724880 | chr8:136554897 | ENST00000318607 | - | 6 | 15 | 294_370 | 292 | 311 | Domain | RRM 4 |
| Hgene | >PABPC1 | chr8:101724880 | chr8:136554897 | ENST00000318607 | - | 6 | 15 | 542_619 | 292 | 311 | Domain | PABC |
| Tgene | KHDRBS3 | chr8:101724880 | chr8:136554897 | ENST00000355849 | + | 1 | 9 | 61_127 | 69 | 347 | Domain | Note=KH |
| Tgene | KHDRBS3 | chr8:101724880 | chr8:136554897 | ENST00000355849 | + | 1 | 9 | 1_160 | 69 | 347 | Region | Involved in homodimerization |
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FusionGeneSequence for PABPC1_KHDRBS3 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_PABPC1_ENST00000318607_chr8_101724880_-_KHDRBS3_ENST00000355849_chr8_136554897_+_570aa MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPVRIMWSQRD PSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKERE AELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKV ERQTELKRKFEQMKQDRITRYQFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKYFHLNDDLHVLIEVFAPP AEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSENADVPVVRGKPTLRTRGVPAPAITRGRGGVTARPVGVVVPRGTPTPRG VLSTRGPVSRGRGLLTPRARGVPPTGYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQSGADYYDYGHGLSEETYDSYG >In-frame_PABPC1_ENST00000519004_chr8_101724880_-_KHDRBS3_ENST00000355849_chr8_136554897_+_525aa MITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDEN GSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTD ESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQFNFVGKLLGPRGNSLKRLQEETL TKMSILGKGSMRDKAKEEELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSENAD VPVVRGKPTLRTRGVPAPAITRGRGGVTARPVGVVVPRGTPTPRGVLSTRGPVSRGRGLLTPRARGVPPTGYRPPPPPPTQETYGEYDYD >In-frame_PABPC1_ENST00000522387_chr8_101724880_-_KHDRBS3_ENST00000355849_chr8_136554897_+_538aa MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPVRIMWSQRD PSLRKSGVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFG KFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQFNFVGKLLGP RGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQ ELTYLNGGSENADVPVVRGKPTLRTRGVPAPAITRGRGGVTARPVGVVVPRGTPTPRGVLSTRGPVSRGRGLLTPRARGVPPTGYRPPPP |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_PABPC1_ENST00000318607_chr8_101724880_-_KHDRBS3_ENST00000355849_chr8_136554897_+_1710nt ATGAACCCCAGTGCCCCCAGCTACCCCATGGCCTCGCTCTACGTGGGGGACCTCCACCCCGACGTGACCGAGGCGATGCTCTACGAGAAG TTCAGCCCGGCCGGGCCCATCCTCTCCATCCGGGTCTGCAGGGACATGATCACCCGCCGCTCCTTGGGCTACGCGTATGTGAACTTCCAG CAGCCGGCGGACGCGGAGCGTGCTTTGGACACCATGAATTTTGATGTTATAAAGGGCAAGCCAGTACGCATCATGTGGTCTCAGCGTGAT CCATCACTTCGCAAAAGTGGAGTAGGCAACATATTCATTAAAAATCTGGACAAATCCATTGATAATAAAGCACTGTATGATACATTTTCT GCTTTTGGTAACATCCTTTCATGTAAGGTGGTTTGTGATGAAAATGGTTCCAAGGGCTATGGATTTGTACACTTTGAGACGCAGGAAGCA GCTGAAAGAGCTATTGAAAAAATGAATGGAATGCTCCTAAATGATCGCAAAGTATTTGTTGGACGATTTAAGTCTCGTAAAGAACGAGAA GCTGAACTTGGAGCTAGGGCAAAAGAATTCACCAATGTTTACATCAAGAATTTTGGAGAAGACATGGATGATGAGCGCCTTAAGGATCTC TTTGGCAAGTTTGGGCCTGCCTTAAGTGTGAAAGTAATGACTGATGAAAGTGGAAAATCCAAAGGATTTGGATTTGTAAGCTTTGAAAGG CATGAAGATGCACAGAAAGCTGTGGATGAGATGAACGGAAAGGAGCTCAATGGAAAACAAATTTATGTTGGTCGAGCTCAGAAAAAGGTG GAACGGCAGACGGAACTTAAGCGCAAATTTGAACAGATGAAACAAGATAGGATCACCAGATACCAGTTCAACTTTGTGGGGAAACTTTTG GGTCCACGTGGCAATTCTCTGAAGCGTTTACAAGAAGAAACCTTGACAAAAATGTCCATCCTTGGGAAAGGTTCCATGAGAGACAAGGCC AAGGAAGAAGAGTTGAGGAAAAGTGGAGAAGCGAAGTACTTCCATCTCAATGATGATCTCCATGTTCTCATTGAAGTGTTTGCCCCACCT GCAGAAGCTTATGCCAGGATGGGACATGCTTTGGAAGAAATCAAAAAGTTCCTCATCCCTGATTATAATGATGAGATCAGGCAAGCACAG CTCCAGGAGTTAACATATTTGAATGGTGGTTCAGAAAATGCAGATGTTCCAGTGGTTCGAGGGAAACCCACCTTGCGTACAAGAGGTGTA CCAGCCCCAGCAATAACCAGGGGAAGGGGAGGAGTTACAGCCCGGCCAGTTGGAGTTGTAGTACCACGAGGGACGCCAACTCCCAGAGGA GTCCTGTCCACCCGAGGGCCAGTGAGTCGGGGAAGAGGACTTCTCACTCCCAGAGCAAGAGGAGTCCCCCCAACTGGGTACAGACCTCCA CCGCCACCCCCGACACAAGAGACTTATGGAGAATATGACTATGATGATGGATATGGCACTGCTTATGATGAACAGAGTTATGATTCCTAT GATAACAGCTATAGCACCCCAGCCCAAAGTGGTGCTGATTACTATGATTACGGACATGGACTCAGTGAGGAGACTTATGATTCCTACGGG CAAGAAGAGTGGACTAACTCAAGACACAAGGCACCTTCAGCGAGGACAGCAAAGGGCGTCTACAGAGACCAGCCATATGGCAGATACTGA >In-frame_PABPC1_ENST00000519004_chr8_101724880_-_KHDRBS3_ENST00000355849_chr8_136554897_+_1575nt ATGATCACCCGCCGCTCCTTGGGCTACGCGTATGTGAACTTCCAGCAGCCGGCGGACGCGGAGCGTGCTTTGGACACCATGAATTTTGAT GTTATAAAGGGCAAGCCAGTACGCATCATGTGGTCTCAGCGTGATCCATCACTTCGCAAAAGTGGAGTAGGCAACATATTCATTAAAAAT CTGGACAAATCCATTGATAATAAAGCACTGTATGATACATTTTCTGCTTTTGGTAACATCCTTTCATGTAAGGTGGTTTGTGATGAAAAT GGTTCCAAGGGCTATGGATTTGTACACTTTGAGACGCAGGAAGCAGCTGAAAGAGCTATTGAAAAAATGAATGGAATGCTCCTAAATGAT CGCAAAGTATTTGTTGGACGATTTAAGTCTCGTAAAGAACGAGAAGCTGAACTTGGAGCTAGGGCAAAAGAATTCACCAATGTTTACATC AAGAATTTTGGAGAAGACATGGATGATGAGCGCCTTAAGGATCTCTTTGGCAAGTTTGGGCCTGCCTTAAGTGTGAAAGTAATGACTGAT GAAAGTGGAAAATCCAAAGGATTTGGATTTGTAAGCTTTGAAAGGCATGAAGATGCACAGAAAGCTGTGGATGAGATGAACGGAAAGGAG CTCAATGGAAAACAAATTTATGTTGGTCGAGCTCAGAAAAAGGTGGAACGGCAGACGGAACTTAAGCGCAAATTTGAACAGATGAAACAA GATAGGATCACCAGATACCAGTTCAACTTTGTGGGGAAACTTTTGGGTCCACGTGGCAATTCTCTGAAGCGTTTACAAGAAGAAACCTTG ACAAAAATGTCCATCCTTGGGAAAGGTTCCATGAGAGACAAGGCCAAGGAAGAAGAGTTGAGGAAAAGTGGAGAAGCGAAGTACTTCCAT CTCAATGATGATCTCCATGTTCTCATTGAAGTGTTTGCCCCACCTGCAGAAGCTTATGCCAGGATGGGACATGCTTTGGAAGAAATCAAA AAGTTCCTCATCCCTGATTATAATGATGAGATCAGGCAAGCACAGCTCCAGGAGTTAACATATTTGAATGGTGGTTCAGAAAATGCAGAT GTTCCAGTGGTTCGAGGGAAACCCACCTTGCGTACAAGAGGTGTACCAGCCCCAGCAATAACCAGGGGAAGGGGAGGAGTTACAGCCCGG CCAGTTGGAGTTGTAGTACCACGAGGGACGCCAACTCCCAGAGGAGTCCTGTCCACCCGAGGGCCAGTGAGTCGGGGAAGAGGACTTCTC ACTCCCAGAGCAAGAGGAGTCCCCCCAACTGGGTACAGACCTCCACCGCCACCCCCGACACAAGAGACTTATGGAGAATATGACTATGAT GATGGATATGGCACTGCTTATGATGAACAGAGTTATGATTCCTATGATAACAGCTATAGCACCCCAGCCCAAAGTGGTGCTGATTACTAT GATTACGGACATGGACTCAGTGAGGAGACTTATGATTCCTACGGGCAAGAAGAGTGGACTAACTCAAGACACAAGGCACCTTCAGCGAGG >In-frame_PABPC1_ENST00000522387_chr8_101724880_-_KHDRBS3_ENST00000355849_chr8_136554897_+_1614nt ATGAACCCCAGTGCCCCCAGCTACCCCATGGCCTCGCTCTACGTGGGGGACCTCCACCCCGACGTGACCGAGGCGATGCTCTACGAGAAG TTCAGCCCGGCCGGGCCCATCCTCTCCATCCGGGTCTGCAGGGACATGATCACCCGCCGCTCCTTGGGCTACGCGTATGTGAACTTCCAG CAGCCGGCGGACGCGGAGCGTGCTTTGGACACCATGAATTTTGATGTTATAAAGGGCAAGCCAGTACGCATCATGTGGTCTCAGCGTGAT CCATCACTTCGCAAAAGTGGAGTGGTTTGTGATGAAAATGGTTCCAAGGGCTATGGATTTGTACACTTTGAGACGCAGGAAGCAGCTGAA AGAGCTATTGAAAAAATGAATGGAATGCTCCTAAATGATCGCAAAGTATTTGTTGGACGATTTAAGTCTCGTAAAGAACGAGAAGCTGAA CTTGGAGCTAGGGCAAAAGAATTCACCAATGTTTACATCAAGAATTTTGGAGAAGACATGGATGATGAGCGCCTTAAGGATCTCTTTGGC AAGTTTGGGCCTGCCTTAAGTGTGAAAGTAATGACTGATGAAAGTGGAAAATCCAAAGGATTTGGATTTGTAAGCTTTGAAAGGCATGAA GATGCACAGAAAGCTGTGGATGAGATGAACGGAAAGGAGCTCAATGGAAAACAAATTTATGTTGGTCGAGCTCAGAAAAAGGTGGAACGG CAGACGGAACTTAAGCGCAAATTTGAACAGATGAAACAAGATAGGATCACCAGATACCAGTTCAACTTTGTGGGGAAACTTTTGGGTCCA CGTGGCAATTCTCTGAAGCGTTTACAAGAAGAAACCTTGACAAAAATGTCCATCCTTGGGAAAGGTTCCATGAGAGACAAGGCCAAGGAA GAAGAGTTGAGGAAAAGTGGAGAAGCGAAGTACTTCCATCTCAATGATGATCTCCATGTTCTCATTGAAGTGTTTGCCCCACCTGCAGAA GCTTATGCCAGGATGGGACATGCTTTGGAAGAAATCAAAAAGTTCCTCATCCCTGATTATAATGATGAGATCAGGCAAGCACAGCTCCAG GAGTTAACATATTTGAATGGTGGTTCAGAAAATGCAGATGTTCCAGTGGTTCGAGGGAAACCCACCTTGCGTACAAGAGGTGTACCAGCC CCAGCAATAACCAGGGGAAGGGGAGGAGTTACAGCCCGGCCAGTTGGAGTTGTAGTACCACGAGGGACGCCAACTCCCAGAGGAGTCCTG TCCACCCGAGGGCCAGTGAGTCGGGGAAGAGGACTTCTCACTCCCAGAGCAAGAGGAGTCCCCCCAACTGGGTACAGACCTCCACCGCCA CCCCCGACACAAGAGACTTATGGAGAATATGACTATGATGATGGATATGGCACTGCTTATGATGAACAGAGTTATGATTCCTATGATAAC AGCTATAGCACCCCAGCCCAAAGTGGTGCTGATTACTATGATTACGGACATGGACTCAGTGAGGAGACTTATGATTCCTACGGGCAAGAA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_PABPC1_ENST00000318607_chr8_101724880_-_KHDRBS3_ENST00000355849_chr8_136554897_+_3365nt CGTAGTGCGGTCCGGGTAGGAGAGAGCAGGGGGCCACGCTGGCTCCATCTACGCACGTTTCGGAAACCGGGCCCGGAGGGGACCACGCCC GCTCACCCGTGCCCGGCGTCCCCCGGAGCTGGGGCTAGAGGAGCCGGGCCGGCCGCAGCGGGAAGAGGCCACAGGCGGCCGCGCACGTGG GGGGTGGTTAGCGCGGAGGAACCCGGAAGCCCTTTGCACCGCCCACCGCCGCGGTGACGGGTTAACGCTCCTCCTGGTGGAGGCAGGGGC GGGCGGGGCGGAAGGCGGGGACGCCTCAGCCAACACCCCCGAGGACCGCCCGCGAGCCGTCCTCCCCACCCCCACGGACGCGACGCAGCG CGGGCTCCGCTTCCCCGGCCGCGGCGCCTGCGCAAAAGCCCCGCCCCTTCGCCCGAGCCCCACCCCCACACCGCAGCCTCCACCGCCGCC ACCTCTCCCTTCCTCTCTGCTCTTTCCTCCTGTTTTCTCTTCCCTCCTCCCCCTGGCCTCCGCGTCTCCTCCTACTCCGGCGCTGACGCT CGCGTAGGGGCCCTGGCGTCAGACGCGCGGGGGCGGGGCGAGTGCGGCGCGGGGTATAAGTAGAGGGTGCAGGAGGCGGTGCTTCCCCTT CTCCCCGGCGGTTAGTGCTGAGAGTGCGGAGTGTGTGCTCCGGGCTCGGAACACACATTTATTATTAAAAAATCCAAAAAAAATCTAAAA AAATCTTTTAAAAAACCCCAAAAAAATTTACAAAAAATCCGCGTCTCCCCCGCCGGAGACTTTTATTTTTTTTCTTCCTCTTTTATAAAA TAACCCGGTGAAGCAGCCGAGACCGACCCGCCCGCCCGCGGCCCCGCAGCAGCTCCAAGAAGGAACCAAGAGACCGAGGCCTTCCCGCTG CCCGGACCCGACACCGCCACCCTCGCTCCCCGCCGGCAGCCGGCAGCCAGCGGCAGTGGATCGACCCCGTTCTGCGGCCGTTGAGTAGTT TTCAATTCCGGTTGATTTTTGTCCCTCTGCGCTTGCTCCCCGCTCCCCTCCCCCCGGCTCCGGCCCCCAGCCCCGGCACTCGCTCTCCTC CTCTCACGGAAAGGTCGCGGCCTGTGGCCCTGCGGGCAGCCGTGCCGAGATGAACCCCAGTGCCCCCAGCTACCCCATGGCCTCGCTCTA CGTGGGGGACCTCCACCCCGACGTGACCGAGGCGATGCTCTACGAGAAGTTCAGCCCGGCCGGGCCCATCCTCTCCATCCGGGTCTGCAG GGACATGATCACCCGCCGCTCCTTGGGCTACGCGTATGTGAACTTCCAGCAGCCGGCGGACGCGGAGCGTGCTTTGGACACCATGAATTT TGATGTTATAAAGGGCAAGCCAGTACGCATCATGTGGTCTCAGCGTGATCCATCACTTCGCAAAAGTGGAGTAGGCAACATATTCATTAA AAATCTGGACAAATCCATTGATAATAAAGCACTGTATGATACATTTTCTGCTTTTGGTAACATCCTTTCATGTAAGGTGGTTTGTGATGA AAATGGTTCCAAGGGCTATGGATTTGTACACTTTGAGACGCAGGAAGCAGCTGAAAGAGCTATTGAAAAAATGAATGGAATGCTCCTAAA TGATCGCAAAGTATTTGTTGGACGATTTAAGTCTCGTAAAGAACGAGAAGCTGAACTTGGAGCTAGGGCAAAAGAATTCACCAATGTTTA CATCAAGAATTTTGGAGAAGACATGGATGATGAGCGCCTTAAGGATCTCTTTGGCAAGTTTGGGCCTGCCTTAAGTGTGAAAGTAATGAC TGATGAAAGTGGAAAATCCAAAGGATTTGGATTTGTAAGCTTTGAAAGGCATGAAGATGCACAGAAAGCTGTGGATGAGATGAACGGAAA GGAGCTCAATGGAAAACAAATTTATGTTGGTCGAGCTCAGAAAAAGGTGGAACGGCAGACGGAACTTAAGCGCAAATTTGAACAGATGAA ACAAGATAGGATCACCAGATACCAGTTCAACTTTGTGGGGAAACTTTTGGGTCCACGTGGCAATTCTCTGAAGCGTTTACAAGAAGAAAC CTTGACAAAAATGTCCATCCTTGGGAAAGGTTCCATGAGAGACAAGGCCAAGGAAGAAGAGTTGAGGAAAAGTGGAGAAGCGAAGTACTT CCATCTCAATGATGATCTCCATGTTCTCATTGAAGTGTTTGCCCCACCTGCAGAAGCTTATGCCAGGATGGGACATGCTTTGGAAGAAAT CAAAAAGTTCCTCATCCCTGATTATAATGATGAGATCAGGCAAGCACAGCTCCAGGAGTTAACATATTTGAATGGTGGTTCAGAAAATGC AGATGTTCCAGTGGTTCGAGGGAAACCCACCTTGCGTACAAGAGGTGTACCAGCCCCAGCAATAACCAGGGGAAGGGGAGGAGTTACAGC CCGGCCAGTTGGAGTTGTAGTACCACGAGGGACGCCAACTCCCAGAGGAGTCCTGTCCACCCGAGGGCCAGTGAGTCGGGGAAGAGGACT TCTCACTCCCAGAGCAAGAGGAGTCCCCCCAACTGGGTACAGACCTCCACCGCCACCCCCGACACAAGAGACTTATGGAGAATATGACTA TGATGATGGATATGGCACTGCTTATGATGAACAGAGTTATGATTCCTATGATAACAGCTATAGCACCCCAGCCCAAAGTGGTGCTGATTA CTATGATTACGGACATGGACTCAGTGAGGAGACTTATGATTCCTACGGGCAAGAAGAGTGGACTAACTCAAGACACAAGGCACCTTCAGC GAGGACAGCAAAGGGCGTCTACAGAGACCAGCCATATGGCAGATACTGATTGTACTGTCTGATGTTGTGAAATAGCCAATCTCCACCAGT CCTGTATACTGTTCAAAGTAATTTTTTTCTATGAACAATCCCTTTTTAAATAAATCAGAATGCTTAAAATCTGAATGGATGGAACTTAAA ACTACTTTGTTGAAACATCAACCTGGGCAGAAAAAAAAAAAAAAAGACATGTAAAATTTTGTTATTTCCAGTCTGTATATGAAAAAATAG GTCATCAAAAGGAAAAAAAATAACTTTGATTAACTAGTGTTAAACAAAAAATAGGTTTACTAAATATGTTAATCTATTCTTTTAACATAA GCCTCACCTTTCATTTTAAAGGTTTCCATAGAATTTAGTTATTTTATCTTTCAGCCATATGCTAGTTTTTTTTTCTCTTGCCAACATGCG TAAAAAGGGAAGCCAATTACAAGTGCAAATAATGTGGTATTCTTTTGTAACTCAAGTCTTGAAATGTTCTGTAGTGTTAAGCAAAGTCTC >In-frame_PABPC1_ENST00000519004_chr8_101724880_-_KHDRBS3_ENST00000355849_chr8_136554897_+_2464nt CCCTTCTCCCCGGCGGTTAGTGCTGAGAGTGCGGAGTGTGTGCTCCGGGCTCGGAACACACATTTATTATTAAAAAATCCAAAAAAAATC TAAAAAAATCTTTTAAAAAACCCCAAAAAAATTTACAAAAAATCCGCGTCTCCCCCGCCGGAGACTTTTATTTTTTTTCTTCCTCTTTTA TAAAATAACCCGGTGAAGCAGCCGAGACCGACCCGCCCGCCCGCGGCCCCGCAGCAGCTCCAAGAAGGAACCAAGAGACCGAGGCCTTCC CGCTGCCCGGACCCGACACCGCCACCCTCGCTCCCCGCCGGCAGCCGGCAGCCAGCGGCAGTGGATCGACCCCGTTCTGCGGCCGTTGAG GACATGATCACCCGCCGCTCCTTGGGCTACGCGTATGTGAACTTCCAGCAGCCGGCGGACGCGGAGCGTGCTTTGGACACCATGAATTTT GATGTTATAAAGGGCAAGCCAGTACGCATCATGTGGTCTCAGCGTGATCCATCACTTCGCAAAAGTGGAGTAGGCAACATATTCATTAAA AATCTGGACAAATCCATTGATAATAAAGCACTGTATGATACATTTTCTGCTTTTGGTAACATCCTTTCATGTAAGGTGGTTTGTGATGAA AATGGTTCCAAGGGCTATGGATTTGTACACTTTGAGACGCAGGAAGCAGCTGAAAGAGCTATTGAAAAAATGAATGGAATGCTCCTAAAT GATCGCAAAGTATTTGTTGGACGATTTAAGTCTCGTAAAGAACGAGAAGCTGAACTTGGAGCTAGGGCAAAAGAATTCACCAATGTTTAC ATCAAGAATTTTGGAGAAGACATGGATGATGAGCGCCTTAAGGATCTCTTTGGCAAGTTTGGGCCTGCCTTAAGTGTGAAAGTAATGACT GATGAAAGTGGAAAATCCAAAGGATTTGGATTTGTAAGCTTTGAAAGGCATGAAGATGCACAGAAAGCTGTGGATGAGATGAACGGAAAG GAGCTCAATGGAAAACAAATTTATGTTGGTCGAGCTCAGAAAAAGGTGGAACGGCAGACGGAACTTAAGCGCAAATTTGAACAGATGAAA CAAGATAGGATCACCAGATACCAGTTCAACTTTGTGGGGAAACTTTTGGGTCCACGTGGCAATTCTCTGAAGCGTTTACAAGAAGAAACC TTGACAAAAATGTCCATCCTTGGGAAAGGTTCCATGAGAGACAAGGCCAAGGAAGAAGAGTTGAGGAAAAGTGGAGAAGCGAAGTACTTC CATCTCAATGATGATCTCCATGTTCTCATTGAAGTGTTTGCCCCACCTGCAGAAGCTTATGCCAGGATGGGACATGCTTTGGAAGAAATC AAAAAGTTCCTCATCCCTGATTATAATGATGAGATCAGGCAAGCACAGCTCCAGGAGTTAACATATTTGAATGGTGGTTCAGAAAATGCA GATGTTCCAGTGGTTCGAGGGAAACCCACCTTGCGTACAAGAGGTGTACCAGCCCCAGCAATAACCAGGGGAAGGGGAGGAGTTACAGCC CGGCCAGTTGGAGTTGTAGTACCACGAGGGACGCCAACTCCCAGAGGAGTCCTGTCCACCCGAGGGCCAGTGAGTCGGGGAAGAGGACTT CTCACTCCCAGAGCAAGAGGAGTCCCCCCAACTGGGTACAGACCTCCACCGCCACCCCCGACACAAGAGACTTATGGAGAATATGACTAT GATGATGGATATGGCACTGCTTATGATGAACAGAGTTATGATTCCTATGATAACAGCTATAGCACCCCAGCCCAAAGTGGTGCTGATTAC TATGATTACGGACATGGACTCAGTGAGGAGACTTATGATTCCTACGGGCAAGAAGAGTGGACTAACTCAAGACACAAGGCACCTTCAGCG AGGACAGCAAAGGGCGTCTACAGAGACCAGCCATATGGCAGATACTGATTGTACTGTCTGATGTTGTGAAATAGCCAATCTCCACCAGTC CTGTATACTGTTCAAAGTAATTTTTTTCTATGAACAATCCCTTTTTAAATAAATCAGAATGCTTAAAATCTGAATGGATGGAACTTAAAA CTACTTTGTTGAAACATCAACCTGGGCAGAAAAAAAAAAAAAAAGACATGTAAAATTTTGTTATTTCCAGTCTGTATATGAAAAAATAGG TCATCAAAAGGAAAAAAAATAACTTTGATTAACTAGTGTTAAACAAAAAATAGGTTTACTAAATATGTTAATCTATTCTTTTAACATAAG CCTCACCTTTCATTTTAAAGGTTTCCATAGAATTTAGTTATTTTATCTTTCAGCCATATGCTAGTTTTTTTTTCTCTTGCCAACATGCGT AAAAAGGGAAGCCAATTACAAGTGCAAATAATGTGGTATTCTTTTGTAACTCAAGTCTTGAAATGTTCTGTAGTGTTAAGCAAAGTCTCC >In-frame_PABPC1_ENST00000522387_chr8_101724880_-_KHDRBS3_ENST00000355849_chr8_136554897_+_2456nt AAATCTTTTAAAAAACCCCAAAAAAATTTACAAAAAATCCGCGTCTCCCCCGCCGGAGACTTTTATTTTTTTTCTTCCTCTTTTATAAAA TAACCCGGTGAAGCAGCCGAGACCGACCCGCCCGCCCGCGGCCCCGCAGCAGCTCCAAGAAGGAACCAAGAGACCGAGGCCTTCCCGCTG CCCGGACCCGACACCGCCACCCTCGCTCCCCGCCGGCAGCCGGCAGCCAGCGGCAGTGGATCGACCCCGTTCTGCGGCCGTTGAGTAGTT TTCAATTCCGGTCGCGGCCTGTGGCCCTGCGGGCAGCCGTGCCGAGATGAACCCCAGTGCCCCCAGCTACCCCATGGCCTCGCTCTACGT GGGGGACCTCCACCCCGACGTGACCGAGGCGATGCTCTACGAGAAGTTCAGCCCGGCCGGGCCCATCCTCTCCATCCGGGTCTGCAGGGA CATGATCACCCGCCGCTCCTTGGGCTACGCGTATGTGAACTTCCAGCAGCCGGCGGACGCGGAGCGTGCTTTGGACACCATGAATTTTGA TGTTATAAAGGGCAAGCCAGTACGCATCATGTGGTCTCAGCGTGATCCATCACTTCGCAAAAGTGGAGTGGTTTGTGATGAAAATGGTTC CAAGGGCTATGGATTTGTACACTTTGAGACGCAGGAAGCAGCTGAAAGAGCTATTGAAAAAATGAATGGAATGCTCCTAAATGATCGCAA AGTATTTGTTGGACGATTTAAGTCTCGTAAAGAACGAGAAGCTGAACTTGGAGCTAGGGCAAAAGAATTCACCAATGTTTACATCAAGAA TTTTGGAGAAGACATGGATGATGAGCGCCTTAAGGATCTCTTTGGCAAGTTTGGGCCTGCCTTAAGTGTGAAAGTAATGACTGATGAAAG TGGAAAATCCAAAGGATTTGGATTTGTAAGCTTTGAAAGGCATGAAGATGCACAGAAAGCTGTGGATGAGATGAACGGAAAGGAGCTCAA TGGAAAACAAATTTATGTTGGTCGAGCTCAGAAAAAGGTGGAACGGCAGACGGAACTTAAGCGCAAATTTGAACAGATGAAACAAGATAG GATCACCAGATACCAGTTCAACTTTGTGGGGAAACTTTTGGGTCCACGTGGCAATTCTCTGAAGCGTTTACAAGAAGAAACCTTGACAAA AATGTCCATCCTTGGGAAAGGTTCCATGAGAGACAAGGCCAAGGAAGAAGAGTTGAGGAAAAGTGGAGAAGCGAAGTACTTCCATCTCAA TGATGATCTCCATGTTCTCATTGAAGTGTTTGCCCCACCTGCAGAAGCTTATGCCAGGATGGGACATGCTTTGGAAGAAATCAAAAAGTT CCTCATCCCTGATTATAATGATGAGATCAGGCAAGCACAGCTCCAGGAGTTAACATATTTGAATGGTGGTTCAGAAAATGCAGATGTTCC AGTGGTTCGAGGGAAACCCACCTTGCGTACAAGAGGTGTACCAGCCCCAGCAATAACCAGGGGAAGGGGAGGAGTTACAGCCCGGCCAGT TGGAGTTGTAGTACCACGAGGGACGCCAACTCCCAGAGGAGTCCTGTCCACCCGAGGGCCAGTGAGTCGGGGAAGAGGACTTCTCACTCC CAGAGCAAGAGGAGTCCCCCCAACTGGGTACAGACCTCCACCGCCACCCCCGACACAAGAGACTTATGGAGAATATGACTATGATGATGG ATATGGCACTGCTTATGATGAACAGAGTTATGATTCCTATGATAACAGCTATAGCACCCCAGCCCAAAGTGGTGCTGATTACTATGATTA CGGACATGGACTCAGTGAGGAGACTTATGATTCCTACGGGCAAGAAGAGTGGACTAACTCAAGACACAAGGCACCTTCAGCGAGGACAGC AAAGGGCGTCTACAGAGACCAGCCATATGGCAGATACTGATTGTACTGTCTGATGTTGTGAAATAGCCAATCTCCACCAGTCCTGTATAC TGTTCAAAGTAATTTTTTTCTATGAACAATCCCTTTTTAAATAAATCAGAATGCTTAAAATCTGAATGGATGGAACTTAAAACTACTTTG TTGAAACATCAACCTGGGCAGAAAAAAAAAAAAAAAGACATGTAAAATTTTGTTATTTCCAGTCTGTATATGAAAAAATAGGTCATCAAA AGGAAAAAAAATAACTTTGATTAACTAGTGTTAAACAAAAAATAGGTTTACTAAATATGTTAATCTATTCTTTTAACATAAGCCTCACCT TTCATTTTAAAGGTTTCCATAGAATTTAGTTATTTTATCTTTCAGCCATATGCTAGTTTTTTTTTCTCTTGCCAACATGCGTAAAAAGGG AAGCCAATTACAAGTGCAAATAATGTGGTATTCTTTTGTAACTCAAGTCTTGAAATGTTCTGTAGTGTTAAGCAAAGTCTCCTCTTGCTT |
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FusionGenePPI for PABPC1_KHDRBS3 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| PABPC1 | ANAPC5, EIF4A2, IKBKE, PINX1, DYNLL1, PUF60, BCAR3, PAN2, UPF1, ETF1, PAN3, CNOT7, TOB1, EIF4B, PXN, PAIP1, GNB2L1, PAIP2, EIF4A1, GSPT2, GSPT1, EIF4G1, EIF4G3, HNRNPA1, AIRE, GIGYF2, H2AFX, PRMT6, HNRNPD, HDAC5, STAU1, HNRNPK, YWHAG, PCBP1, PCBP2, SREK1, NDRG1, ELAVL1, ARRB2, SIRT7, ZFP36, NCL, SH3KBP1, TSG101, TNRC6A, TNRC6B, TNRC6C, ATXN2, IGBP1, PPP2CA, NFX1, PABPC1, UBR5, CUL3, CUL4A, CUL4B, CUL5, CUL2, CUL1, COPS5, COPS6, DCUN1D1, CAND1, NEDD8, CHAF1A, CNOT6, TOB2, MEX3B, MEX3A, MEX3C, BRCA1, SMAD3, PAIP2B, FBXO6, SYNCRIP, HNRNPU, HNRNPR, SNRNP200, DHX15, SNW1, ILF3, EEF1A1, RPS21, RPS4X, RPSA, RPS28, RPL4, RPL7, RPL7A, RPL13, RALY, SNRPD3, SART1, PRPF3, SNRPA, RPL5, EEF2, ATP6V1B2, ATP5A1, ESR1, HBB, USP10, G3BP1, FN1, VCAM1, U2AF1, RBM4, IFIT1, IFIT2, IFIT3, AGO1, AGO2, IL7R, UBL4A, ITGA4, MAPKAPK2, SMG1, RBM8A, CD81, IGSF8, ICAM1, RUVBL1, TERT, BAG3, CSF2, TARDBP, CLK3, SRPK2, SRPK1, CLK2, ITCH, WBP4, APBB1, PIN1, WWOX, APEX1, P4HB, GNPDA1, SGTA, UBA1, PSMD9, TMOD3, RPA1, RPA2, RPA3, HAUS1, CEP250, TP53, WWP2, SMG6, R3HCC1L, TDRD3, CUL7, OBSL1, CCDC8, ZMYND11, FBXW11, MAEL, ACAT2, CSTF2, DDX19A, EEF1G, FDPS, G3BP2, HSPA8, KIN, LUC7L2, MIF, MSI2, NHP2L1, ORC4, ALYREF, ATXN2L, BRIX1, CSTF3, DDX39A, DDX39B, EEF1A2, EIF4E, PFAS, PHGDH, POLE, RAE1, RPL13A, RPL18, RPL35, SFN, SKIV2L2, UAP1, PAPOLA, PAPOLB, PDCD6, PLRG1, PREP, PRPF8, RPL10A, RPL11, RPL14, RPL15, RPL17, RPL18A, RPL27, RPL27A, RPL3, RPL37A, RPL39, RPL6, RPLP0, RPLP2, RPS16, RPS3A, RPS6, RPS8, SERBP1, SF3A1, SUMO1, NTRK1, XPO1, HIST1H3E, RPL10, GAN, SKI, CRY1, MKRN1, MCM2, U2AF2, ELAVL2, TRA2A, SNRNP70, CYLD, COX15, DLD, DLST, DNM1L, HSD17B10, PARK7, PDHA1, VDAC1, TRIM25, PRNP, DCAF4L2 | KHDRBS3 | ZNF408, BAHD1, PSMF1, RBMX, CCDC33, LNX1, NUDT18, RBM7, HNRNPK, KHDRBS2, SIAH1, PRMT1, SGSM2, RPAP2, CACNA1A, RBBP6, SERPINB5, FBXO32, SNRPC, U2AF2, PTBP2, KHDRBS3, KHDRBS1, HNRNPC, FUS, NELFB, INPP5D, PRPF31, NCOA5, MARK4, DMRT3, YTHDC1, BMI1, FBXW11, ATXN2, HNRNPR, SYNCRIP, IFI16, PPP1R13B, G3BP1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for PABPC1_KHDRBS3 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for PABPC1_KHDRBS3 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | PABPC1 | C0005695 | Bladder Neoplasm | 1 | CTD_human |
| Hgene | PABPC1 | C0007138 | Carcinoma, Transitional Cell | 1 | CTD_human |
| Hgene | PABPC1 | C1458155 | Mammary Neoplasms | 1 | CTD_human |
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