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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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Fusion gene ID: 2558

FusionGeneSummary for ARHGEF2_AGO3

check button Fusion gene summary
Fusion gene informationFusion gene name: ARHGEF2_AGO3
Fusion gene ID: 2558
HgeneTgene
Gene symbol

ARHGEF2

AGO3

Gene ID

9181

192669

Gene nameRho/Rac guanine nucleotide exchange factor 2argonaute 3, RISC catalytic component
SynonymsGEF|GEF-H1|GEFH1|LFP40|NEDMHM|P40EIF2C3
Cytomap

1q22

1p34.3

Type of geneprotein-codingprotein-coding
Descriptionrho guanine nucleotide exchange factor 2Rho/Rac guanine nucleotide exchange factor (GEF) 2guanine nucleotide exchange factor H1microtubule-regulated Rho-GEFproliferating cell nucleolar antigen p40protein argonaute-3argonaute RISC catalytic component 3eukaryotic translation initiation factor 2C, 3hAgo3
Modification date2018052220180522
UniProtAcc

Q92974

Q9H9G7

Ensembl transtripts involved in fusion geneENST00000368315, ENST00000313695, 
ENST00000361247, ENST00000368316, 
ENST00000462460, ENST00000477754, 
ENST00000313667, 
ENST00000324350, 
ENST00000373191, ENST00000397828, 
ENST00000246314, ENST00000471099, 
Fusion gene scores* DoF score9 X 8 X 9=6488 X 5 X 8=320
# samples 108
** MAII scorelog2(10/648*10)=-2.6959938131099
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(8/320*10)=-2
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ARHGEF2 [Title/Abstract] AND AGO3 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneARHGEF2

GO:0032755

positive regulation of interleukin-6 production

21887730

HgeneARHGEF2

GO:0032760

positive regulation of tumor necrosis factor production

21887730

HgeneARHGEF2

GO:0045666

positive regulation of neuron differentiation

28453519

HgeneARHGEF2

GO:0045944

positive regulation of transcription by RNA polymerase II

21887730

HgeneARHGEF2

GO:0050731

positive regulation of peptidyl-tyrosine phosphorylation

21887730

HgeneARHGEF2

GO:0051092

positive regulation of NF-kappaB transcription factor activity

19043560|21887730

HgeneARHGEF2

GO:0055059

asymmetric neuroblast division

28453519

HgeneARHGEF2

GO:0071225

cellular response to muramyl dipeptide

21887730

TgeneAGO3

GO:0006402

mRNA catabolic process

18771919

TgeneAGO3

GO:0010501

RNA secondary structure unwinding

19966796

TgeneAGO3

GO:0031054

pre-miRNA processing

19966796

TgeneAGO3

GO:0035278

miRNA mediated inhibition of translation

18771919

TgeneAGO3

GO:0035279

mRNA cleavage involved in gene silencing by miRNA

15260970

TgeneAGO3

GO:0035280

miRNA loading onto RISC involved in gene silencing by miRNA

19966796

TgeneAGO3

GO:0090625

mRNA cleavage involved in gene silencing by siRNA

15260970


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDKIRCTCGA-CW-6097-01AARHGEF2chr1

155927504

-AGO3chr1

36432556

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000368315ENST00000324350ARHGEF2chr1

155927504

-AGO3chr1

36432556

+
In-frameENST00000368315ENST00000373191ARHGEF2chr1

155927504

-AGO3chr1

36432556

+
In-frameENST00000368315ENST00000397828ARHGEF2chr1

155927504

-AGO3chr1

36432556

+
5CDS-intronENST00000368315ENST00000246314ARHGEF2chr1

155927504

-AGO3chr1

36432556

+
5CDS-intronENST00000368315ENST00000471099ARHGEF2chr1

155927504

-AGO3chr1

36432556

+
In-frameENST00000313695ENST00000324350ARHGEF2chr1

155927504

-AGO3chr1

36432556

+
In-frameENST00000313695ENST00000373191ARHGEF2chr1

155927504

-AGO3chr1

36432556

+
In-frameENST00000313695ENST00000397828ARHGEF2chr1

155927504

-AGO3chr1

36432556

+
5CDS-intronENST00000313695ENST00000246314ARHGEF2chr1

155927504

-AGO3chr1

36432556

+
5CDS-intronENST00000313695ENST00000471099ARHGEF2chr1

155927504

-AGO3chr1

36432556

+
In-frameENST00000361247ENST00000324350ARHGEF2chr1

155927504

-AGO3chr1

36432556

+
In-frameENST00000361247ENST00000373191ARHGEF2chr1

155927504

-AGO3chr1

36432556

+
In-frameENST00000361247ENST00000397828ARHGEF2chr1

155927504

-AGO3chr1

36432556

+
5CDS-intronENST00000361247ENST00000246314ARHGEF2chr1

155927504

-AGO3chr1

36432556

+
5CDS-intronENST00000361247ENST00000471099ARHGEF2chr1

155927504

-AGO3chr1

36432556

+
Frame-shitENST00000368316ENST00000324350ARHGEF2chr1

155927504

-AGO3chr1

36432556

+
Frame-shitENST00000368316ENST00000373191ARHGEF2chr1

155927504

-AGO3chr1

36432556

+
Frame-shitENST00000368316ENST00000397828ARHGEF2chr1

155927504

-AGO3chr1

36432556

+
5CDS-intronENST00000368316ENST00000246314ARHGEF2chr1

155927504

-AGO3chr1

36432556

+
5CDS-intronENST00000368316ENST00000471099ARHGEF2chr1

155927504

-AGO3chr1

36432556

+
Frame-shitENST00000462460ENST00000324350ARHGEF2chr1

155927504

-AGO3chr1

36432556

+
Frame-shitENST00000462460ENST00000373191ARHGEF2chr1

155927504

-AGO3chr1

36432556

+
Frame-shitENST00000462460ENST00000397828ARHGEF2chr1

155927504

-AGO3chr1

36432556

+
5CDS-intronENST00000462460ENST00000246314ARHGEF2chr1

155927504

-AGO3chr1

36432556

+
5CDS-intronENST00000462460ENST00000471099ARHGEF2chr1

155927504

-AGO3chr1

36432556

+
intron-3CDSENST00000477754ENST00000324350ARHGEF2chr1

155927504

-AGO3chr1

36432556

+
intron-3CDSENST00000477754ENST00000373191ARHGEF2chr1

155927504

-AGO3chr1

36432556

+
intron-3CDSENST00000477754ENST00000397828ARHGEF2chr1

155927504

-AGO3chr1

36432556

+
intron-intronENST00000477754ENST00000246314ARHGEF2chr1

155927504

-AGO3chr1

36432556

+
intron-intronENST00000477754ENST00000471099ARHGEF2chr1

155927504

-AGO3chr1

36432556

+
In-frameENST00000313667ENST00000324350ARHGEF2chr1

155927504

-AGO3chr1

36432556

+
In-frameENST00000313667ENST00000373191ARHGEF2chr1

155927504

-AGO3chr1

36432556

+
In-frameENST00000313667ENST00000397828ARHGEF2chr1

155927504

-AGO3chr1

36432556

+
5CDS-intronENST00000313667ENST00000246314ARHGEF2chr1

155927504

-AGO3chr1

36432556

+
5CDS-intronENST00000313667ENST00000471099ARHGEF2chr1

155927504

-AGO3chr1

36432556

+

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FusionProtFeatures for ARHGEF2_AGO3


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ARHGEF2

Q92974

AGO3

Q9H9G7

Activates Rho-GTPases by promoting the exchange of GDPfor GTP. May be involved in epithelial barrier permeability, cellmotility and polarization, dendritic spine morphology, antigenpresentation, leukemic cell differentiation, cell cycleregulation, innate immune response, and cancer. Binds Rac-GTPases,but does not seem to promote nucleotide exchange activity towardRac-GTPases, which was uniquely reported in PubMed:9857026. Maystimulate instead the cortical activity of Rac. Inactive towardCDC42, TC10, or Ras-GTPases. Forms an intracellular sensing systemalong with NOD1 for the detection of microbial effectors duringcell invasion by pathogens. Required for RHOA and RIP2 dependentNF-kappaB signaling pathways activation upon S.flexneri cellinvasion. Involved not only in sensing peptidoglycan (PGN)-derivedmuropeptides through NOD1 that is independent of its GEF activity,but also in the activation of NF-kappaB by Shigella effectorproteins (IpgB2 and OspB) which requires its GEF activity and theactivation of RhoA. Involved in innate immune signalingtransduction pathway promoting cytokine IL6/interleukin-6 and TNF-alpha secretion in macrophage upon stimulation by bacterialpeptidoglycans; acts as a signaling intermediate between NOD2receptor and RIPK2 kinase. Contributes to the tyrosinephosphorylation of RIPK2 through Src tyrosine kinase leading toNF-kappaB activation by NOD2. Overexpression activates Rho-, butnot Rac-GTPases, and increases paracellular permeability (Bysimilarity). Involved in neuronal progenitor cell division anddifferentiation (PubMed:28453519). Involved in the migration ofprecerebellar neurons (By similarity).{ECO:0000250|UniProtKB:Q60875, ECO:0000250|UniProtKB:Q865S3,ECO:0000269|PubMed:19043560, ECO:0000269|PubMed:21887730,ECO:0000269|PubMed:28453519, ECO:0000269|PubMed:9857026}. Required for RNA-mediated gene silencing (RNAi). Bindsto short RNAs such as microRNAs (miRNAs) and represses thetranslation of mRNAs which are complementary to them. Proposed tobe involved in stabilization of small RNA derivates (riRNA)derived from processed RNA polymerase III-transcribed Alu repeatscontaining a DR2 retinoic acid response element (RARE) in stemcells and in the subsequent riRNA-dependent degradation of asubset of RNA polymerase II-transcribed coding mRNAs by recruitinga mRNA decapping complex involving EDC4. Possesses RNA sliceractivity but only on select RNAs bearing 5'- and 3'-flankingsequences to the region of guide-target complementarity(PubMed:29040713). {ECO:0000255|HAMAP-Rule:MF_03032,ECO:0000269|PubMed:18771919, ECO:0000269|PubMed:23064648,ECO:0000269|PubMed:29040713}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneARHGEF2chr1:155927504chr1:36432556ENST00000313667-1322235_432570986DomainDH
HgeneARHGEF2chr1:155927504chr1:36432556ENST00000313667-1322472_571570986DomainPH
HgeneARHGEF2chr1:155927504chr1:36432556ENST00000313695-1322235_432543959DomainDH
HgeneARHGEF2chr1:155927504chr1:36432556ENST00000361247-1322235_432571987DomainDH
HgeneARHGEF2chr1:155927504chr1:36432556ENST00000361247-1322472_571571987DomainPH
HgeneARHGEF2chr1:155927504chr1:36432556ENST00000368316-1726235_432543959DomainDH
HgeneARHGEF2chr1:155927504chr1:36432556ENST00000313667-132239_86570986Zinc fingerPhorbol-ester/DAG-type
HgeneARHGEF2chr1:155927504chr1:36432556ENST00000313695-132239_86543959Zinc fingerPhorbol-ester/DAG-type
HgeneARHGEF2chr1:155927504chr1:36432556ENST00000361247-132239_86571987Zinc fingerPhorbol-ester/DAG-type
HgeneARHGEF2chr1:155927504chr1:36432556ENST00000368316-172639_86543959Zinc fingerPhorbol-ester/DAG-type
TgeneAGO3chr1:155927504chr1:36432556ENST00000246314+017236_349-205627DomainPAZ
TgeneAGO3chr1:155927504chr1:36432556ENST00000246314+017518_819-205627DomainPiwi
TgeneAGO3chr1:155927504chr1:36432556ENST00000373191+119236_34963861DomainPAZ
TgeneAGO3chr1:155927504chr1:36432556ENST00000373191+119518_81963861DomainPiwi

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneARHGEF2chr1:155927504chr1:36432556ENST00000313667-1322587_611570986Coiled coilOntology_term=ECO:0000255
HgeneARHGEF2chr1:155927504chr1:36432556ENST00000313667-1322798_867570986Coiled coilOntology_term=ECO:0000255
HgeneARHGEF2chr1:155927504chr1:36432556ENST00000313695-1322587_611543959Coiled coilOntology_term=ECO:0000255
HgeneARHGEF2chr1:155927504chr1:36432556ENST00000313695-1322798_867543959Coiled coilOntology_term=ECO:0000255
HgeneARHGEF2chr1:155927504chr1:36432556ENST00000361247-1322587_611571987Coiled coilOntology_term=ECO:0000255
HgeneARHGEF2chr1:155927504chr1:36432556ENST00000361247-1322798_867571987Coiled coilOntology_term=ECO:0000255
HgeneARHGEF2chr1:155927504chr1:36432556ENST00000368316-1726587_611543959Coiled coilOntology_term=ECO:0000255
HgeneARHGEF2chr1:155927504chr1:36432556ENST00000368316-1726798_867543959Coiled coilOntology_term=ECO:0000255
HgeneARHGEF2chr1:155927504chr1:36432556ENST00000313695-1322472_571543959DomainPH
HgeneARHGEF2chr1:155927504chr1:36432556ENST00000368316-1726472_571543959DomainPH


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FusionGeneSequence for ARHGEF2_AGO3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_ARHGEF2_ENST00000368315_chr1_155927504_-_AGO3_ENST00000324350_chr1_36432556_+_739aa
MCCCCGCCPLLAHLEQGSLRERTREKEKMKEAKDARTTNGHLFTTISVSGMTMCTACNKSITAKEALICPTCNVTIHNRCKDTLANCTKV
KQKQQKAALLKNNTALQSVSLRSKTTIRERPSSAIYPSDSFRQSLLGSRRGRSSLSLAKSVSTTNIAGHFNDESPLGLRRILSQSTDSLN
MRNRTLSVESLIDEAEVIYSELMSDFEMDEKDFAADSWSLAVDSSFLQQHKKEVMKQQDVITELIQTELHHVRTLKIMTRLFRTGMLEEL
HLEPGVVQGLFPCVDELSDIHTRFLSQLLERRRQALCPGSTRNFVIHRLGDLLISQFSGPSAEQMCKTYSEFCSRHSKALKLTKELYARD
KRFQQFIRKVTRPAVLKRHGVQECILLVTQRITKYPLLISRILQHSHGIEEERQDLTTALGLVKELLSNVDEGITQLEKGARLQEIYNRM
DPRAQTPVPGKGPFGREELLRRKLIHDGCLLWKTATGRFKDVLVLLMTDVLVFLQEKDQKYIFPTLDKPSVVSLQNLIVRDIANQEKGMF
LISAAPPEMYEVHTASRDDRSTWIRVIQQSVRTEVVDSMVQHFKVTIFGDRRPVTDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPF
KVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGTDHPLGGGREVWFGFHQSVRPAM

>In-frame_ARHGEF2_ENST00000368315_chr1_155927504_-_AGO3_ENST00000373191_chr1_36432556_+_1370aa
MCCCCGCCPLLAHLEQGSLRERTREKEKMKEAKDARTTNGHLFTTISVSGMTMCTACNKSITAKEALICPTCNVTIHNRCKDTLANCTKV
KQKQQKAALLKNNTALQSVSLRSKTTIRERPSSAIYPSDSFRQSLLGSRRGRSSLSLAKSVSTTNIAGHFNDESPLGLRRILSQSTDSLN
MRNRTLSVESLIDEAEVIYSELMSDFEMDEKDFAADSWSLAVDSSFLQQHKKEVMKQQDVITELIQTELHHVRTLKIMTRLFRTGMLEEL
HLEPGVVQGLFPCVDELSDIHTRFLSQLLERRRQALCPGSTRNFVIHRLGDLLISQFSGPSAEQMCKTYSEFCSRHSKALKLTKELYARD
KRFQQFIRKVTRPAVLKRHGVQECILLVTQRITKYPLLISRILQHSHGIEEERQDLTTALGLVKELLSNVDEGITQLEKGARLQEIYNRM
DPRAQTPVPGKGPFGREELLRRKLIHDGCLLWKTATGRFKDVLVLLMTDVLVFLQEKDQKYIFPTLDKPSVVSLQNLIVRDIANQEKGMF
LISAAPPEMYEVHTASRDDRSTWIRVIQQSVRTEVVDSMVQHFKVTIFGDRRPVTDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPF
KVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGTDHPLGGGREVWFGFHQSVRPAM
WKMMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLEN
GQTVERTVAQTFREKTTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANTET
DPFVQEFQFKVRDEMAHVTGRVLPAPMLQTGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKD
AGMPIQGQPCFCKTAQGADSVEPMFRHLKNTTSGLQLIIVILPGKTPVTAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVK
LGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFTKSTRFK
PTRIIFTRDGVSEGQFRQVLTTELLAIREACISLEKDTQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPTEFDFYL
CSHAGIQGTSRPSHTHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPATTAHLVAFRARTHLVDKEHDSAEGSHVSGQSNGRDPQ

>In-frame_ARHGEF2_ENST00000368315_chr1_155927504_-_AGO3_ENST00000397828_chr1_36432556_+_739aa
MCCCCGCCPLLAHLEQGSLRERTREKEKMKEAKDARTTNGHLFTTISVSGMTMCTACNKSITAKEALICPTCNVTIHNRCKDTLANCTKV
KQKQQKAALLKNNTALQSVSLRSKTTIRERPSSAIYPSDSFRQSLLGSRRGRSSLSLAKSVSTTNIAGHFNDESPLGLRRILSQSTDSLN
MRNRTLSVESLIDEAEVIYSELMSDFEMDEKDFAADSWSLAVDSSFLQQHKKEVMKQQDVITELIQTELHHVRTLKIMTRLFRTGMLEEL
HLEPGVVQGLFPCVDELSDIHTRFLSQLLERRRQALCPGSTRNFVIHRLGDLLISQFSGPSAEQMCKTYSEFCSRHSKALKLTKELYARD
KRFQQFIRKVTRPAVLKRHGVQECILLVTQRITKYPLLISRILQHSHGIEEERQDLTTALGLVKELLSNVDEGITQLEKGARLQEIYNRM
DPRAQTPVPGKGPFGREELLRRKLIHDGCLLWKTATGRFKDVLVLLMTDVLVFLQEKDQKYIFPTLDKPSVVSLQNLIVRDIANQEKGMF
LISAAPPEMYEVHTASRDDRSTWIRVIQQSVRTEVVDSMVQHFKVTIFGDRRPVTDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPF
KVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGTDHPLGGGREVWFGFHQSVRPAM

>In-frame_ARHGEF2_ENST00000313695_chr1_155927504_-_AGO3_ENST00000324350_chr1_36432556_+_710aa
MKEAKDARTTNGHLFTTISVSGMTMCTACNKSITAKEALICPTCNVTIHNRCKDTLANCTKVKQKQQKAALLKNNTALQSVSLRSKTTIR
ERPSSAIYPSDSFRQSLLGSRRGRSSLSLAKSVSTTNIAGHFNDESPLGLRRILSQSTDSLNMRNRTLSVESLIDEEVIYSELMSDFEMD
EKDFAADSWSLAVDSSFLQQHKKEVMKQQDVITELIQTELHHVRTLKIMTRLFRTGMLEELHLEPGVVQGLFPCVDELSDIHTRFLSQLL
ERRRQALCPGSTRNFVIHRLGDLLISQFSGPSAEQMCKTYSEFCSRHSKALKLTKELYARDKRFQQFIRKVTRPAVLKRHGVQECILLVT
QRITKYPLLISRILQHSHGIEEERQDLTTALGLVKELLSNVDEGITQLEKGARLQEIYNRMDPRAQTPVPGKGPFGREELLRRKLIHDGC
LLWKTATGRFKDVLVLLMTDVLVFLQEKDQKYIFPTLDKPSVVSLQNLIVRDIANQEKGMFLISAAPPEMYEVHTASRDDRSTWIRVIQQ
SVRTEVVDSMVQHFKVTIFGDRRPVTDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPFKVSIKFVSRVSWHLLHEVLTGRTLPEPLE

>In-frame_ARHGEF2_ENST00000313695_chr1_155927504_-_AGO3_ENST00000373191_chr1_36432556_+_1341aa
MKEAKDARTTNGHLFTTISVSGMTMCTACNKSITAKEALICPTCNVTIHNRCKDTLANCTKVKQKQQKAALLKNNTALQSVSLRSKTTIR
ERPSSAIYPSDSFRQSLLGSRRGRSSLSLAKSVSTTNIAGHFNDESPLGLRRILSQSTDSLNMRNRTLSVESLIDEEVIYSELMSDFEMD
EKDFAADSWSLAVDSSFLQQHKKEVMKQQDVITELIQTELHHVRTLKIMTRLFRTGMLEELHLEPGVVQGLFPCVDELSDIHTRFLSQLL
ERRRQALCPGSTRNFVIHRLGDLLISQFSGPSAEQMCKTYSEFCSRHSKALKLTKELYARDKRFQQFIRKVTRPAVLKRHGVQECILLVT
QRITKYPLLISRILQHSHGIEEERQDLTTALGLVKELLSNVDEGITQLEKGARLQEIYNRMDPRAQTPVPGKGPFGREELLRRKLIHDGC
LLWKTATGRFKDVLVLLMTDVLVFLQEKDQKYIFPTLDKPSVVSLQNLIVRDIANQEKGMFLISAAPPEMYEVHTASRDDRSTWIRVIQQ
SVRTEVVDSMVQHFKVTIFGDRRPVTDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPFKVSIKFVSRVSWHLLHEVLTGRTLPEPLE
LDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGTDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLD
IHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQTFREKTTLQLKYPHLPCLQ
VGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANTETDPFVQEFQFKVRDEMAHVTGRVLPAPMLQ
TGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKTAQGADSVEPMFRHLK
NTTSGLQLIIVILPGKTPVTAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVT
HPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFTKSTRFKPTRIIFTRDGVSEGQFRQVLTTELLAIRE
ACISLEKDTQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPTEFDFYLCSHAGIQGTSRPSHTHVLWDDNCFTADEL

>In-frame_ARHGEF2_ENST00000313695_chr1_155927504_-_AGO3_ENST00000397828_chr1_36432556_+_710aa
MKEAKDARTTNGHLFTTISVSGMTMCTACNKSITAKEALICPTCNVTIHNRCKDTLANCTKVKQKQQKAALLKNNTALQSVSLRSKTTIR
ERPSSAIYPSDSFRQSLLGSRRGRSSLSLAKSVSTTNIAGHFNDESPLGLRRILSQSTDSLNMRNRTLSVESLIDEEVIYSELMSDFEMD
EKDFAADSWSLAVDSSFLQQHKKEVMKQQDVITELIQTELHHVRTLKIMTRLFRTGMLEELHLEPGVVQGLFPCVDELSDIHTRFLSQLL
ERRRQALCPGSTRNFVIHRLGDLLISQFSGPSAEQMCKTYSEFCSRHSKALKLTKELYARDKRFQQFIRKVTRPAVLKRHGVQECILLVT
QRITKYPLLISRILQHSHGIEEERQDLTTALGLVKELLSNVDEGITQLEKGARLQEIYNRMDPRAQTPVPGKGPFGREELLRRKLIHDGC
LLWKTATGRFKDVLVLLMTDVLVFLQEKDQKYIFPTLDKPSVVSLQNLIVRDIANQEKGMFLISAAPPEMYEVHTASRDDRSTWIRVIQQ
SVRTEVVDSMVQHFKVTIFGDRRPVTDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPFKVSIKFVSRVSWHLLHEVLTGRTLPEPLE

>In-frame_ARHGEF2_ENST00000361247_chr1_155927504_-_AGO3_ENST00000324350_chr1_36432556_+_738aa
MSRIESLTRARIDRSRELASKTREKEKMKEAKDARTTNGHLFTTISVSGMTMCTACNKSITAKEALICPTCNVTIHNRCKDTLANCTKVK
QKQQKAALLKNNTALQSVSLRSKTTIRERPSSAIYPSDSFRQSLLGSRRGRSSLSLAKSVSTTNIAGHFNDESPLGLRRILSQSTDSLNM
RNRTLSVESLIDEAEVIYSELMSDFEMDEKDFAADSWSLAVDSSFLQQHKKEVMKQQDVITELIQTELHHVRTLKIMTRLFRTGMLEELH
LEPGVVQGLFPCVDELSDIHTRFLSQLLERRRQALCPGSTRNFVIHRLGDLLISQFSGPSAEQMCKTYSEFCSRHSKALKLTKELYARDK
RFQQFIRKVTRPAVLKRHGVQECILLVTQRITKYPLLISRILQHSHGIEEERQDLTTALGLVKELLSNVDEGITQLEKGARLQEIYNRMD
PRAQTPVPGKGPFGREELLRRKLIHDGCLLWKTATGRFKDVLVLLMTDVLVFLQEKDQKYIFPTLDKPSVVSLQNLIVRDIANQEKGMFL
ISAAPPEMYEVHTASRDDRSTWIRVIQQSVRTEVVDSMVQHFKVTIFGDRRPVTDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPFK
VSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGTDHPLGGGREVWFGFHQSVRPAMW

>In-frame_ARHGEF2_ENST00000361247_chr1_155927504_-_AGO3_ENST00000373191_chr1_36432556_+_1369aa
MSRIESLTRARIDRSRELASKTREKEKMKEAKDARTTNGHLFTTISVSGMTMCTACNKSITAKEALICPTCNVTIHNRCKDTLANCTKVK
QKQQKAALLKNNTALQSVSLRSKTTIRERPSSAIYPSDSFRQSLLGSRRGRSSLSLAKSVSTTNIAGHFNDESPLGLRRILSQSTDSLNM
RNRTLSVESLIDEAEVIYSELMSDFEMDEKDFAADSWSLAVDSSFLQQHKKEVMKQQDVITELIQTELHHVRTLKIMTRLFRTGMLEELH
LEPGVVQGLFPCVDELSDIHTRFLSQLLERRRQALCPGSTRNFVIHRLGDLLISQFSGPSAEQMCKTYSEFCSRHSKALKLTKELYARDK
RFQQFIRKVTRPAVLKRHGVQECILLVTQRITKYPLLISRILQHSHGIEEERQDLTTALGLVKELLSNVDEGITQLEKGARLQEIYNRMD
PRAQTPVPGKGPFGREELLRRKLIHDGCLLWKTATGRFKDVLVLLMTDVLVFLQEKDQKYIFPTLDKPSVVSLQNLIVRDIANQEKGMFL
ISAAPPEMYEVHTASRDDRSTWIRVIQQSVRTEVVDSMVQHFKVTIFGDRRPVTDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPFK
VSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGTDHPLGGGREVWFGFHQSVRPAMW
KMMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENG
QTVERTVAQTFREKTTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANTETD
PFVQEFQFKVRDEMAHVTGRVLPAPMLQTGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDA
GMPIQGQPCFCKTAQGADSVEPMFRHLKNTTSGLQLIIVILPGKTPVTAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKL
GGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFTKSTRFKP
TRIIFTRDGVSEGQFRQVLTTELLAIREACISLEKDTQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPTEFDFYLC
SHAGIQGTSRPSHTHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPATTAHLVAFRARTHLVDKEHDSAEGSHVSGQSNGRDPQA

>In-frame_ARHGEF2_ENST00000361247_chr1_155927504_-_AGO3_ENST00000397828_chr1_36432556_+_738aa
MSRIESLTRARIDRSRELASKTREKEKMKEAKDARTTNGHLFTTISVSGMTMCTACNKSITAKEALICPTCNVTIHNRCKDTLANCTKVK
QKQQKAALLKNNTALQSVSLRSKTTIRERPSSAIYPSDSFRQSLLGSRRGRSSLSLAKSVSTTNIAGHFNDESPLGLRRILSQSTDSLNM
RNRTLSVESLIDEAEVIYSELMSDFEMDEKDFAADSWSLAVDSSFLQQHKKEVMKQQDVITELIQTELHHVRTLKIMTRLFRTGMLEELH
LEPGVVQGLFPCVDELSDIHTRFLSQLLERRRQALCPGSTRNFVIHRLGDLLISQFSGPSAEQMCKTYSEFCSRHSKALKLTKELYARDK
RFQQFIRKVTRPAVLKRHGVQECILLVTQRITKYPLLISRILQHSHGIEEERQDLTTALGLVKELLSNVDEGITQLEKGARLQEIYNRMD
PRAQTPVPGKGPFGREELLRRKLIHDGCLLWKTATGRFKDVLVLLMTDVLVFLQEKDQKYIFPTLDKPSVVSLQNLIVRDIANQEKGMFL
ISAAPPEMYEVHTASRDDRSTWIRVIQQSVRTEVVDSMVQHFKVTIFGDRRPVTDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPFK
VSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGTDHPLGGGREVWFGFHQSVRPAMW

>In-frame_ARHGEF2_ENST00000313667_chr1_155927504_-_AGO3_ENST00000324350_chr1_36432556_+_737aa
MSRIESLTRARIDRSRELASKTREKEKMKEAKDARTTNGHLFTTISVSGMTMCTACNKSITAKEALICPTCNVTIHNRCKDTLANCTKVK
QKQQKAALLKNNTALQSVSLRSKTTIRERPSSAIYPSDSFRQSLLGSRRGRSSLSLAKSVSTTNIAGHFNDESPLGLRRILSQSTDSLNM
RNRTLSVESLIDEEVIYSELMSDFEMDEKDFAADSWSLAVDSSFLQQHKKEVMKQQDVITELIQTELHHVRTLKIMTRLFRTGMLEELHL
EPGVVQGLFPCVDELSDIHTRFLSQLLERRRQALCPGSTRNFVIHRLGDLLISQFSGPSAEQMCKTYSEFCSRHSKALKLTKELYARDKR
FQQFIRKVTRPAVLKRHGVQECILLVTQRITKYPLLISRILQHSHGIEEERQDLTTALGLVKELLSNVDEGITQLEKGARLQEIYNRMDP
RAQTPVPGKGPFGREELLRRKLIHDGCLLWKTATGRFKDVLVLLMTDVLVFLQEKDQKYIFPTLDKPSVVSLQNLIVRDIANQEKGMFLI
SAAPPEMYEVHTASRDDRSTWIRVIQQSVRTEVVDSMVQHFKVTIFGDRRPVTDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPFKV
SIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGTDHPLGGGREVWFGFHQSVRPAMWK

>In-frame_ARHGEF2_ENST00000313667_chr1_155927504_-_AGO3_ENST00000373191_chr1_36432556_+_1368aa
MSRIESLTRARIDRSRELASKTREKEKMKEAKDARTTNGHLFTTISVSGMTMCTACNKSITAKEALICPTCNVTIHNRCKDTLANCTKVK
QKQQKAALLKNNTALQSVSLRSKTTIRERPSSAIYPSDSFRQSLLGSRRGRSSLSLAKSVSTTNIAGHFNDESPLGLRRILSQSTDSLNM
RNRTLSVESLIDEEVIYSELMSDFEMDEKDFAADSWSLAVDSSFLQQHKKEVMKQQDVITELIQTELHHVRTLKIMTRLFRTGMLEELHL
EPGVVQGLFPCVDELSDIHTRFLSQLLERRRQALCPGSTRNFVIHRLGDLLISQFSGPSAEQMCKTYSEFCSRHSKALKLTKELYARDKR
FQQFIRKVTRPAVLKRHGVQECILLVTQRITKYPLLISRILQHSHGIEEERQDLTTALGLVKELLSNVDEGITQLEKGARLQEIYNRMDP
RAQTPVPGKGPFGREELLRRKLIHDGCLLWKTATGRFKDVLVLLMTDVLVFLQEKDQKYIFPTLDKPSVVSLQNLIVRDIANQEKGMFLI
SAAPPEMYEVHTASRDDRSTWIRVIQQSVRTEVVDSMVQHFKVTIFGDRRPVTDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPFKV
SIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGTDHPLGGGREVWFGFHQSVRPAMWK
MMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQ
TVERTVAQTFREKTTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANTETDP
FVQEFQFKVRDEMAHVTGRVLPAPMLQTGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAG
MPIQGQPCFCKTAQGADSVEPMFRHLKNTTSGLQLIIVILPGKTPVTAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLG
GINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFTKSTRFKPT
RIIFTRDGVSEGQFRQVLTTELLAIREACISLEKDTQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPTEFDFYLCS
HAGIQGTSRPSHTHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPATTAHLVAFRARTHLVDKEHDSAEGSHVSGQSNGRDPQAL

>In-frame_ARHGEF2_ENST00000313667_chr1_155927504_-_AGO3_ENST00000397828_chr1_36432556_+_737aa
MSRIESLTRARIDRSRELASKTREKEKMKEAKDARTTNGHLFTTISVSGMTMCTACNKSITAKEALICPTCNVTIHNRCKDTLANCTKVK
QKQQKAALLKNNTALQSVSLRSKTTIRERPSSAIYPSDSFRQSLLGSRRGRSSLSLAKSVSTTNIAGHFNDESPLGLRRILSQSTDSLNM
RNRTLSVESLIDEEVIYSELMSDFEMDEKDFAADSWSLAVDSSFLQQHKKEVMKQQDVITELIQTELHHVRTLKIMTRLFRTGMLEELHL
EPGVVQGLFPCVDELSDIHTRFLSQLLERRRQALCPGSTRNFVIHRLGDLLISQFSGPSAEQMCKTYSEFCSRHSKALKLTKELYARDKR
FQQFIRKVTRPAVLKRHGVQECILLVTQRITKYPLLISRILQHSHGIEEERQDLTTALGLVKELLSNVDEGITQLEKGARLQEIYNRMDP
RAQTPVPGKGPFGREELLRRKLIHDGCLLWKTATGRFKDVLVLLMTDVLVFLQEKDQKYIFPTLDKPSVVSLQNLIVRDIANQEKGMFLI
SAAPPEMYEVHTASRDDRSTWIRVIQQSVRTEVVDSMVQHFKVTIFGDRRPVTDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPFKV
SIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGTDHPLGGGREVWFGFHQSVRPAMWK


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_ARHGEF2_ENST00000368315_chr1_155927504_-_AGO3_ENST00000324350_chr1_36432556_+_2217nt
ATGTGCTGCTGCTGTGGCTGCTGCCCGCTGCTGGCCCACCTAGAGCAGGGGTCACTTCGAGAGAGGACCCGGGAAAAGGAGAAGATGAAG
GAAGCCAAGGATGCCCGCTATACCAATGGGCACCTCTTCACCACCATTTCAGTTTCAGGCATGACCATGTGCTATGCCTGTAACAAGAGC
ATCACAGCCAAGGAAGCCCTCATCTGCCCAACCTGCAATGTGACTATCCACAACCGCTGTAAAGACACCCTCGCCAACTGTACCAAGGTC
AAGCAGAAGCAACAGAAAGCGGCCCTGCTGAAGAACAACACCGCCTTGCAGTCCGTTTCTCTTCGAAGTAAGACAACCATCCGGGAGCGG
CCAAGCTCGGCCATCTACCCCTCCGACAGCTTCCGGCAGTCCCTCCTGGGCTCCCGCCGTGGCCGCTCCTCCTTGTCTTTAGCCAAGAGT
GTTTCTACCACCAACATTGCTGGACATTTCAATGATGAGTCTCCCCTGGGGCTGCGCCGGATCCTCTCACAGTCCACAGACTCCCTCAAC
ATGCGGAACCGAACCCTATCCGTGGAATCCCTCATTGACGAAGCAGAGGTAATCTACAGTGAGCTGATGAGTGACTTTGAGATGGATGAG
AAGGACTTTGCAGCTGACTCTTGGAGTCTTGCTGTGGACAGCAGCTTCCTGCAGCAGCATAAAAAGGAGGTGATGAAGCAGCAAGATGTC
ATCTATGAGCTAATCCAGACAGAGCTGCACCATGTGAGGACACTGAAGATCATGACCCGCCTCTTCCGCACGGGGATGCTGGAAGAGCTA
CACTTGGAGCCAGGAGTGGTCCAGGGCCTGTTCCCCTGCGTGGACGAGCTCAGTGACATCCATACACGCTTCCTCAGCCAGCTATTAGAA
CGCCGACGCCAGGCCCTGTGCCCTGGCAGCACCCGGAACTTTGTCATCCATCGCTTGGGTGATCTGCTCATCAGCCAGTTCTCAGGTCCT
AGTGCGGAGCAGATGTGTAAGACCTACTCGGAGTTCTGCAGCCGCCACAGCAAGGCCTTAAAGCTCTATAAGGAGCTGTACGCCCGAGAC
AAACGCTTCCAGCAATTCATCCGGAAAGTGACCCGCCCCGCCGTGCTCAAGCGGCACGGGGTACAGGAGTGCATCCTGCTGGTGACTCAG
CGCATCACCAAGTACCCGTTACTCATCAGCCGCATCCTGCAGCATTCCCACGGGATCGAGGAGGAGCGCCAGGACCTGACCACAGCACTG
GGGCTAGTGAAGGAGCTGCTGTCCAATGTGGACGAGGGTATTTATCAGCTGGAGAAAGGGGCCCGTCTGCAGGAGATCTACAACCGCATG
GACCCTCGGGCCCAAACCCCAGTGCCTGGCAAGGGCCCCTTTGGCCGAGAGGAACTTCTGAGGCGCAAACTCATCCACGATGGCTGCCTG
CTCTGGAAGACAGCGACGGGGCGCTTCAAAGATGTGCTAGTGCTGCTGATGACAGATGTACTGGTGTTTCTCCAGGAAAAGGACCAGAAG
TACATCTTTCCTACCCTGGACAAGCCTTCAGTGGTATCGCTGCAGAATCTAATCGTACGAGACATTGCCAACCAGGAGAAAGGGATGTTT
CTGATCAGCGCAGCCCCACCTGAGATGTACGAGGTGCACACAGCATCCCGGGATGACCGGAGCACCTGGATCCGGGTCATTCAGCAGAGC
GTGCGCACGGAGGTGGTTGACTCAATGGTTCAGCATTTTAAAGTAACTATATTTGGAGACCGTAGACCAGTTTATGATGGAAAAAGAAGT
CTTTACACCGCCAATCCACTTCCTGTGGCAACTACAGGGGTAGATTTAGACGTTACTTTACCTGGGGAAGGTGGAAAAGATCGACCTTTC
AAGGTGTCAATCAAATTTGTCTCTCGGGTGAGTTGGCACCTACTGCATGAAGTACTGACAGGACGGACCTTGCCTGAGCCACTGGAATTA
GACAAGCCAATCAGCACTAACCCTGTCCATGCCGTTGATGTGGTGCTACGACATCTGCCCTCCATGAAATACACACCTGTGGGGCGTTCA
TTTTTCTCCGCTCCAGAAGGATATGACCACCCTCTGGGAGGGGGCAGGGAAGTGTGGTTTGGATTCCATCAGTCTGTTCGGCCTGCCATG

>In-frame_ARHGEF2_ENST00000368315_chr1_155927504_-_AGO3_ENST00000373191_chr1_36432556_+_4110nt
ATGTGCTGCTGCTGTGGCTGCTGCCCGCTGCTGGCCCACCTAGAGCAGGGGTCACTTCGAGAGAGGACCCGGGAAAAGGAGAAGATGAAG
GAAGCCAAGGATGCCCGCTATACCAATGGGCACCTCTTCACCACCATTTCAGTTTCAGGCATGACCATGTGCTATGCCTGTAACAAGAGC
ATCACAGCCAAGGAAGCCCTCATCTGCCCAACCTGCAATGTGACTATCCACAACCGCTGTAAAGACACCCTCGCCAACTGTACCAAGGTC
AAGCAGAAGCAACAGAAAGCGGCCCTGCTGAAGAACAACACCGCCTTGCAGTCCGTTTCTCTTCGAAGTAAGACAACCATCCGGGAGCGG
CCAAGCTCGGCCATCTACCCCTCCGACAGCTTCCGGCAGTCCCTCCTGGGCTCCCGCCGTGGCCGCTCCTCCTTGTCTTTAGCCAAGAGT
GTTTCTACCACCAACATTGCTGGACATTTCAATGATGAGTCTCCCCTGGGGCTGCGCCGGATCCTCTCACAGTCCACAGACTCCCTCAAC
ATGCGGAACCGAACCCTATCCGTGGAATCCCTCATTGACGAAGCAGAGGTAATCTACAGTGAGCTGATGAGTGACTTTGAGATGGATGAG
AAGGACTTTGCAGCTGACTCTTGGAGTCTTGCTGTGGACAGCAGCTTCCTGCAGCAGCATAAAAAGGAGGTGATGAAGCAGCAAGATGTC
ATCTATGAGCTAATCCAGACAGAGCTGCACCATGTGAGGACACTGAAGATCATGACCCGCCTCTTCCGCACGGGGATGCTGGAAGAGCTA
CACTTGGAGCCAGGAGTGGTCCAGGGCCTGTTCCCCTGCGTGGACGAGCTCAGTGACATCCATACACGCTTCCTCAGCCAGCTATTAGAA
CGCCGACGCCAGGCCCTGTGCCCTGGCAGCACCCGGAACTTTGTCATCCATCGCTTGGGTGATCTGCTCATCAGCCAGTTCTCAGGTCCT
AGTGCGGAGCAGATGTGTAAGACCTACTCGGAGTTCTGCAGCCGCCACAGCAAGGCCTTAAAGCTCTATAAGGAGCTGTACGCCCGAGAC
AAACGCTTCCAGCAATTCATCCGGAAAGTGACCCGCCCCGCCGTGCTCAAGCGGCACGGGGTACAGGAGTGCATCCTGCTGGTGACTCAG
CGCATCACCAAGTACCCGTTACTCATCAGCCGCATCCTGCAGCATTCCCACGGGATCGAGGAGGAGCGCCAGGACCTGACCACAGCACTG
GGGCTAGTGAAGGAGCTGCTGTCCAATGTGGACGAGGGTATTTATCAGCTGGAGAAAGGGGCCCGTCTGCAGGAGATCTACAACCGCATG
GACCCTCGGGCCCAAACCCCAGTGCCTGGCAAGGGCCCCTTTGGCCGAGAGGAACTTCTGAGGCGCAAACTCATCCACGATGGCTGCCTG
CTCTGGAAGACAGCGACGGGGCGCTTCAAAGATGTGCTAGTGCTGCTGATGACAGATGTACTGGTGTTTCTCCAGGAAAAGGACCAGAAG
TACATCTTTCCTACCCTGGACAAGCCTTCAGTGGTATCGCTGCAGAATCTAATCGTACGAGACATTGCCAACCAGGAGAAAGGGATGTTT
CTGATCAGCGCAGCCCCACCTGAGATGTACGAGGTGCACACAGCATCCCGGGATGACCGGAGCACCTGGATCCGGGTCATTCAGCAGAGC
GTGCGCACGGAGGTGGTTGACTCAATGGTTCAGCATTTTAAAGTAACTATATTTGGAGACCGTAGACCAGTTTATGATGGAAAAAGAAGT
CTTTACACCGCCAATCCACTTCCTGTGGCAACTACAGGGGTAGATTTAGACGTTACTTTACCTGGGGAAGGTGGAAAAGATCGACCTTTC
AAGGTGTCAATCAAATTTGTCTCTCGGGTGAGTTGGCACCTACTGCATGAAGTACTGACAGGACGGACCTTGCCTGAGCCACTGGAATTA
GACAAGCCAATCAGCACTAACCCTGTCCATGCCGTTGATGTGGTGCTACGACATCTGCCCTCCATGAAATACACACCTGTGGGGCGTTCA
TTTTTCTCCGCTCCAGAAGGATATGACCACCCTCTGGGAGGGGGCAGGGAAGTGTGGTTTGGATTCCATCAGTCTGTTCGGCCTGCCATG
TGGAAAATGATGCTTAATATCGATGTTTCTGCCACTGCCTTCTACAAAGCACAACCTGTAATTCAGTTCATGTGTGAAGTTCTTGATATT
CATAATATTGATGAGCAACCAAGACCTCTGACTGATTCTCATCGGGTAAAATTCACCAAAGAGATAAAAGGTTTGAAGGTTGAAGTGACT
CATTGTGGAACAATGAGACGGAAATACCGTGTTTGTAATGTAACAAGGAGGCCTGCCAGTCATCAAACCTTTCCTTTACAGTTAGAAAAC
GGCCAAACTGTGGAGAGAACAGTAGCGCAGTATTTCAGAGAAAAGTATACTCTTCAGCTGAAGTACCCGCACCTTCCCTGTCTGCAAGTC
GGGCAGGAACAGAAACACACCTACCTGCCACTAGAAGTCTGTAATATTGTGGCAGGGCAACGATGTATCAAGAAGCTAACAGACAATCAG
ACTTCCACTATGATCAAGGCAACAGCAAGATCTGCACCAGATAGACAAGAGGAAATTAGCAGATTGGTAAGAAGTGCAAATTATGAAACA
GATCCATTTGTTCAGGAGTTTCAATTTAAAGTTCGGGATGAAATGGCTCATGTAACTGGACGCGTACTTCCAGCACCTATGCTCCAGTAT
GGAGGACGGAATCGGACAGTAGCAACACCGAGCCATGGAGTATGGGACATGCGAGGGAAACAATTCCACACAGGAGTTGAAATCAAAATG
TGGGCTATCGCTTGTTTTGCCACACAGAGGCAGTGCAGAGAAGAAATATTGAAGGGTTTCACAGACCAGCTGCGTAAGATTTCTAAGGAT
GCAGGGATGCCCATCCAGGGCCAGCCATGCTTCTGCAAATATGCACAGGGGGCAGACAGCGTAGAGCCCATGTTCCGGCATCTCAAGAAC
ACATATTCTGGCCTACAGCTTATTATCGTCATCCTGCCGGGGAAGACACCAGTGTATGCGGAAGTGAAACGTGTAGGAGACACACTTTTG
GGTATGGCTACACAATGTGTTCAAGTCAAGAATGTAATAAAAACATCTCCTCAAACTCTGTCAAACTTGTGCCTAAAGATAAATGTTAAA
CTCGGAGGGATCAATAATATTCTTGTACCTCATCAAAGACCTTCTGTGTTCCAGCAACCAGTGATCTTTTTGGGAGCCGATGTCACTCAT
CCACCTGCTGGTGATGGAAAGAAGCCTTCTATTGCTGCTGTTGTAGGTAGTATGGATGCACACCCAAGCAGATACTGTGCCACAGTAAGA
GTTCAGAGACCCCGACAGGAGATCATCCAGGACTTGGCCTCCATGGTCCGGGAACTTCTTATTCAATTTTATAAGTCAACTCGGTTCAAG
CCTACTCGTATCATCTTTTATCGGGATGGTGTTTCAGAGGGGCAGTTTAGGCAGGTATTATATTATGAACTACTAGCAATTCGAGAAGCC
TGCATCAGTTTGGAGAAAGACTATCAACCTGGAATAACCTACATTGTAGTTCAGAAGAGACATCACACTCGATTATTTTGTGCTGATAGG
ACAGAAAGGGTTGGAAGAAGTGGCAATATCCCAGCTGGAACAACAGTTGATACAGACATTACACACCCATATGAGTTCGATTTTTACCTC
TGTAGCCATGCTGGAATACAGGGTACCAGTCGTCCTTCACACTATCATGTTTTATGGGATGATAACTGCTTTACTGCAGATGAACTTCAG
CTGCTAACTTACCAGCTCTGCCACACTTACGTACGCTGTACACGATCTGTTTCTATACCTGCACCAGCGTATTATGCTCACCTGGTAGCA
TTTAGAGCCAGATATCATCTTGTGGACAAAGAACATGACAGTGCTGAAGGAAGTCACGTTTCAGGACAAAGCAATGGGCGAGATCCACAA

>In-frame_ARHGEF2_ENST00000368315_chr1_155927504_-_AGO3_ENST00000397828_chr1_36432556_+_2217nt
ATGTGCTGCTGCTGTGGCTGCTGCCCGCTGCTGGCCCACCTAGAGCAGGGGTCACTTCGAGAGAGGACCCGGGAAAAGGAGAAGATGAAG
GAAGCCAAGGATGCCCGCTATACCAATGGGCACCTCTTCACCACCATTTCAGTTTCAGGCATGACCATGTGCTATGCCTGTAACAAGAGC
ATCACAGCCAAGGAAGCCCTCATCTGCCCAACCTGCAATGTGACTATCCACAACCGCTGTAAAGACACCCTCGCCAACTGTACCAAGGTC
AAGCAGAAGCAACAGAAAGCGGCCCTGCTGAAGAACAACACCGCCTTGCAGTCCGTTTCTCTTCGAAGTAAGACAACCATCCGGGAGCGG
CCAAGCTCGGCCATCTACCCCTCCGACAGCTTCCGGCAGTCCCTCCTGGGCTCCCGCCGTGGCCGCTCCTCCTTGTCTTTAGCCAAGAGT
GTTTCTACCACCAACATTGCTGGACATTTCAATGATGAGTCTCCCCTGGGGCTGCGCCGGATCCTCTCACAGTCCACAGACTCCCTCAAC
ATGCGGAACCGAACCCTATCCGTGGAATCCCTCATTGACGAAGCAGAGGTAATCTACAGTGAGCTGATGAGTGACTTTGAGATGGATGAG
AAGGACTTTGCAGCTGACTCTTGGAGTCTTGCTGTGGACAGCAGCTTCCTGCAGCAGCATAAAAAGGAGGTGATGAAGCAGCAAGATGTC
ATCTATGAGCTAATCCAGACAGAGCTGCACCATGTGAGGACACTGAAGATCATGACCCGCCTCTTCCGCACGGGGATGCTGGAAGAGCTA
CACTTGGAGCCAGGAGTGGTCCAGGGCCTGTTCCCCTGCGTGGACGAGCTCAGTGACATCCATACACGCTTCCTCAGCCAGCTATTAGAA
CGCCGACGCCAGGCCCTGTGCCCTGGCAGCACCCGGAACTTTGTCATCCATCGCTTGGGTGATCTGCTCATCAGCCAGTTCTCAGGTCCT
AGTGCGGAGCAGATGTGTAAGACCTACTCGGAGTTCTGCAGCCGCCACAGCAAGGCCTTAAAGCTCTATAAGGAGCTGTACGCCCGAGAC
AAACGCTTCCAGCAATTCATCCGGAAAGTGACCCGCCCCGCCGTGCTCAAGCGGCACGGGGTACAGGAGTGCATCCTGCTGGTGACTCAG
CGCATCACCAAGTACCCGTTACTCATCAGCCGCATCCTGCAGCATTCCCACGGGATCGAGGAGGAGCGCCAGGACCTGACCACAGCACTG
GGGCTAGTGAAGGAGCTGCTGTCCAATGTGGACGAGGGTATTTATCAGCTGGAGAAAGGGGCCCGTCTGCAGGAGATCTACAACCGCATG
GACCCTCGGGCCCAAACCCCAGTGCCTGGCAAGGGCCCCTTTGGCCGAGAGGAACTTCTGAGGCGCAAACTCATCCACGATGGCTGCCTG
CTCTGGAAGACAGCGACGGGGCGCTTCAAAGATGTGCTAGTGCTGCTGATGACAGATGTACTGGTGTTTCTCCAGGAAAAGGACCAGAAG
TACATCTTTCCTACCCTGGACAAGCCTTCAGTGGTATCGCTGCAGAATCTAATCGTACGAGACATTGCCAACCAGGAGAAAGGGATGTTT
CTGATCAGCGCAGCCCCACCTGAGATGTACGAGGTGCACACAGCATCCCGGGATGACCGGAGCACCTGGATCCGGGTCATTCAGCAGAGC
GTGCGCACGGAGGTGGTTGACTCAATGGTTCAGCATTTTAAAGTAACTATATTTGGAGACCGTAGACCAGTTTATGATGGAAAAAGAAGT
CTTTACACCGCCAATCCACTTCCTGTGGCAACTACAGGGGTAGATTTAGACGTTACTTTACCTGGGGAAGGTGGAAAAGATCGACCTTTC
AAGGTGTCAATCAAATTTGTCTCTCGGGTGAGTTGGCACCTACTGCATGAAGTACTGACAGGACGGACCTTGCCTGAGCCACTGGAATTA
GACAAGCCAATCAGCACTAACCCTGTCCATGCCGTTGATGTGGTGCTACGACATCTGCCCTCCATGAAATACACACCTGTGGGGCGTTCA
TTTTTCTCCGCTCCAGAAGGATATGACCACCCTCTGGGAGGGGGCAGGGAAGTGTGGTTTGGATTCCATCAGTCTGTTCGGCCTGCCATG

>In-frame_ARHGEF2_ENST00000313695_chr1_155927504_-_AGO3_ENST00000324350_chr1_36432556_+_2130nt
ATGAAGGAAGCCAAGGATGCCCGCTATACCAATGGGCACCTCTTCACCACCATTTCAGTTTCAGGCATGACCATGTGCTATGCCTGTAAC
AAGAGCATCACAGCCAAGGAAGCCCTCATCTGCCCAACCTGCAATGTGACTATCCACAACCGCTGTAAAGACACCCTCGCCAACTGTACC
AAGGTCAAGCAGAAGCAACAGAAAGCGGCCCTGCTGAAGAACAACACCGCCTTGCAGTCCGTTTCTCTTCGAAGTAAGACAACCATCCGG
GAGCGGCCAAGCTCGGCCATCTACCCCTCCGACAGCTTCCGGCAGTCCCTCCTGGGCTCCCGCCGTGGCCGCTCCTCCTTGTCTTTAGCC
AAGAGTGTTTCTACCACCAACATTGCTGGACATTTCAATGATGAGTCTCCCCTGGGGCTGCGCCGGATCCTCTCACAGTCCACAGACTCC
CTCAACATGCGGAACCGAACCCTATCCGTGGAATCCCTCATTGACGAAGAGGTAATCTACAGTGAGCTGATGAGTGACTTTGAGATGGAT
GAGAAGGACTTTGCAGCTGACTCTTGGAGTCTTGCTGTGGACAGCAGCTTCCTGCAGCAGCATAAAAAGGAGGTGATGAAGCAGCAAGAT
GTCATCTATGAGCTAATCCAGACAGAGCTGCACCATGTGAGGACACTGAAGATCATGACCCGCCTCTTCCGCACGGGGATGCTGGAAGAG
CTACACTTGGAGCCAGGAGTGGTCCAGGGCCTGTTCCCCTGCGTGGACGAGCTCAGTGACATCCATACACGCTTCCTCAGCCAGCTATTA
GAACGCCGACGCCAGGCCCTGTGCCCTGGCAGCACCCGGAACTTTGTCATCCATCGCTTGGGTGATCTGCTCATCAGCCAGTTCTCAGGT
CCTAGTGCGGAGCAGATGTGTAAGACCTACTCGGAGTTCTGCAGCCGCCACAGCAAGGCCTTAAAGCTCTATAAGGAGCTGTACGCCCGA
GACAAACGCTTCCAGCAATTCATCCGGAAAGTGACCCGCCCCGCCGTGCTCAAGCGGCACGGGGTACAGGAGTGCATCCTGCTGGTGACT
CAGCGCATCACCAAGTACCCGTTACTCATCAGCCGCATCCTGCAGCATTCCCACGGGATCGAGGAGGAGCGCCAGGACCTGACCACAGCA
CTGGGGCTAGTGAAGGAGCTGCTGTCCAATGTGGACGAGGGTATTTATCAGCTGGAGAAAGGGGCCCGTCTGCAGGAGATCTACAACCGC
ATGGACCCTCGGGCCCAAACCCCAGTGCCTGGCAAGGGCCCCTTTGGCCGAGAGGAACTTCTGAGGCGCAAACTCATCCACGATGGCTGC
CTGCTCTGGAAGACAGCGACGGGGCGCTTCAAAGATGTGCTAGTGCTGCTGATGACAGATGTACTGGTGTTTCTCCAGGAAAAGGACCAG
AAGTACATCTTTCCTACCCTGGACAAGCCTTCAGTGGTATCGCTGCAGAATCTAATCGTACGAGACATTGCCAACCAGGAGAAAGGGATG
TTTCTGATCAGCGCAGCCCCACCTGAGATGTACGAGGTGCACACAGCATCCCGGGATGACCGGAGCACCTGGATCCGGGTCATTCAGCAG
AGCGTGCGCACGGAGGTGGTTGACTCAATGGTTCAGCATTTTAAAGTAACTATATTTGGAGACCGTAGACCAGTTTATGATGGAAAAAGA
AGTCTTTACACCGCCAATCCACTTCCTGTGGCAACTACAGGGGTAGATTTAGACGTTACTTTACCTGGGGAAGGTGGAAAAGATCGACCT
TTCAAGGTGTCAATCAAATTTGTCTCTCGGGTGAGTTGGCACCTACTGCATGAAGTACTGACAGGACGGACCTTGCCTGAGCCACTGGAA
TTAGACAAGCCAATCAGCACTAACCCTGTCCATGCCGTTGATGTGGTGCTACGACATCTGCCCTCCATGAAATACACACCTGTGGGGCGT
TCATTTTTCTCCGCTCCAGAAGGATATGACCACCCTCTGGGAGGGGGCAGGGAAGTGTGGTTTGGATTCCATCAGTCTGTTCGGCCTGCC

>In-frame_ARHGEF2_ENST00000313695_chr1_155927504_-_AGO3_ENST00000373191_chr1_36432556_+_4023nt
ATGAAGGAAGCCAAGGATGCCCGCTATACCAATGGGCACCTCTTCACCACCATTTCAGTTTCAGGCATGACCATGTGCTATGCCTGTAAC
AAGAGCATCACAGCCAAGGAAGCCCTCATCTGCCCAACCTGCAATGTGACTATCCACAACCGCTGTAAAGACACCCTCGCCAACTGTACC
AAGGTCAAGCAGAAGCAACAGAAAGCGGCCCTGCTGAAGAACAACACCGCCTTGCAGTCCGTTTCTCTTCGAAGTAAGACAACCATCCGG
GAGCGGCCAAGCTCGGCCATCTACCCCTCCGACAGCTTCCGGCAGTCCCTCCTGGGCTCCCGCCGTGGCCGCTCCTCCTTGTCTTTAGCC
AAGAGTGTTTCTACCACCAACATTGCTGGACATTTCAATGATGAGTCTCCCCTGGGGCTGCGCCGGATCCTCTCACAGTCCACAGACTCC
CTCAACATGCGGAACCGAACCCTATCCGTGGAATCCCTCATTGACGAAGAGGTAATCTACAGTGAGCTGATGAGTGACTTTGAGATGGAT
GAGAAGGACTTTGCAGCTGACTCTTGGAGTCTTGCTGTGGACAGCAGCTTCCTGCAGCAGCATAAAAAGGAGGTGATGAAGCAGCAAGAT
GTCATCTATGAGCTAATCCAGACAGAGCTGCACCATGTGAGGACACTGAAGATCATGACCCGCCTCTTCCGCACGGGGATGCTGGAAGAG
CTACACTTGGAGCCAGGAGTGGTCCAGGGCCTGTTCCCCTGCGTGGACGAGCTCAGTGACATCCATACACGCTTCCTCAGCCAGCTATTA
GAACGCCGACGCCAGGCCCTGTGCCCTGGCAGCACCCGGAACTTTGTCATCCATCGCTTGGGTGATCTGCTCATCAGCCAGTTCTCAGGT
CCTAGTGCGGAGCAGATGTGTAAGACCTACTCGGAGTTCTGCAGCCGCCACAGCAAGGCCTTAAAGCTCTATAAGGAGCTGTACGCCCGA
GACAAACGCTTCCAGCAATTCATCCGGAAAGTGACCCGCCCCGCCGTGCTCAAGCGGCACGGGGTACAGGAGTGCATCCTGCTGGTGACT
CAGCGCATCACCAAGTACCCGTTACTCATCAGCCGCATCCTGCAGCATTCCCACGGGATCGAGGAGGAGCGCCAGGACCTGACCACAGCA
CTGGGGCTAGTGAAGGAGCTGCTGTCCAATGTGGACGAGGGTATTTATCAGCTGGAGAAAGGGGCCCGTCTGCAGGAGATCTACAACCGC
ATGGACCCTCGGGCCCAAACCCCAGTGCCTGGCAAGGGCCCCTTTGGCCGAGAGGAACTTCTGAGGCGCAAACTCATCCACGATGGCTGC
CTGCTCTGGAAGACAGCGACGGGGCGCTTCAAAGATGTGCTAGTGCTGCTGATGACAGATGTACTGGTGTTTCTCCAGGAAAAGGACCAG
AAGTACATCTTTCCTACCCTGGACAAGCCTTCAGTGGTATCGCTGCAGAATCTAATCGTACGAGACATTGCCAACCAGGAGAAAGGGATG
TTTCTGATCAGCGCAGCCCCACCTGAGATGTACGAGGTGCACACAGCATCCCGGGATGACCGGAGCACCTGGATCCGGGTCATTCAGCAG
AGCGTGCGCACGGAGGTGGTTGACTCAATGGTTCAGCATTTTAAAGTAACTATATTTGGAGACCGTAGACCAGTTTATGATGGAAAAAGA
AGTCTTTACACCGCCAATCCACTTCCTGTGGCAACTACAGGGGTAGATTTAGACGTTACTTTACCTGGGGAAGGTGGAAAAGATCGACCT
TTCAAGGTGTCAATCAAATTTGTCTCTCGGGTGAGTTGGCACCTACTGCATGAAGTACTGACAGGACGGACCTTGCCTGAGCCACTGGAA
TTAGACAAGCCAATCAGCACTAACCCTGTCCATGCCGTTGATGTGGTGCTACGACATCTGCCCTCCATGAAATACACACCTGTGGGGCGT
TCATTTTTCTCCGCTCCAGAAGGATATGACCACCCTCTGGGAGGGGGCAGGGAAGTGTGGTTTGGATTCCATCAGTCTGTTCGGCCTGCC
ATGTGGAAAATGATGCTTAATATCGATGTTTCTGCCACTGCCTTCTACAAAGCACAACCTGTAATTCAGTTCATGTGTGAAGTTCTTGAT
ATTCATAATATTGATGAGCAACCAAGACCTCTGACTGATTCTCATCGGGTAAAATTCACCAAAGAGATAAAAGGTTTGAAGGTTGAAGTG
ACTCATTGTGGAACAATGAGACGGAAATACCGTGTTTGTAATGTAACAAGGAGGCCTGCCAGTCATCAAACCTTTCCTTTACAGTTAGAA
AACGGCCAAACTGTGGAGAGAACAGTAGCGCAGTATTTCAGAGAAAAGTATACTCTTCAGCTGAAGTACCCGCACCTTCCCTGTCTGCAA
GTCGGGCAGGAACAGAAACACACCTACCTGCCACTAGAAGTCTGTAATATTGTGGCAGGGCAACGATGTATCAAGAAGCTAACAGACAAT
CAGACTTCCACTATGATCAAGGCAACAGCAAGATCTGCACCAGATAGACAAGAGGAAATTAGCAGATTGGTAAGAAGTGCAAATTATGAA
ACAGATCCATTTGTTCAGGAGTTTCAATTTAAAGTTCGGGATGAAATGGCTCATGTAACTGGACGCGTACTTCCAGCACCTATGCTCCAG
TATGGAGGACGGAATCGGACAGTAGCAACACCGAGCCATGGAGTATGGGACATGCGAGGGAAACAATTCCACACAGGAGTTGAAATCAAA
ATGTGGGCTATCGCTTGTTTTGCCACACAGAGGCAGTGCAGAGAAGAAATATTGAAGGGTTTCACAGACCAGCTGCGTAAGATTTCTAAG
GATGCAGGGATGCCCATCCAGGGCCAGCCATGCTTCTGCAAATATGCACAGGGGGCAGACAGCGTAGAGCCCATGTTCCGGCATCTCAAG
AACACATATTCTGGCCTACAGCTTATTATCGTCATCCTGCCGGGGAAGACACCAGTGTATGCGGAAGTGAAACGTGTAGGAGACACACTT
TTGGGTATGGCTACACAATGTGTTCAAGTCAAGAATGTAATAAAAACATCTCCTCAAACTCTGTCAAACTTGTGCCTAAAGATAAATGTT
AAACTCGGAGGGATCAATAATATTCTTGTACCTCATCAAAGACCTTCTGTGTTCCAGCAACCAGTGATCTTTTTGGGAGCCGATGTCACT
CATCCACCTGCTGGTGATGGAAAGAAGCCTTCTATTGCTGCTGTTGTAGGTAGTATGGATGCACACCCAAGCAGATACTGTGCCACAGTA
AGAGTTCAGAGACCCCGACAGGAGATCATCCAGGACTTGGCCTCCATGGTCCGGGAACTTCTTATTCAATTTTATAAGTCAACTCGGTTC
AAGCCTACTCGTATCATCTTTTATCGGGATGGTGTTTCAGAGGGGCAGTTTAGGCAGGTATTATATTATGAACTACTAGCAATTCGAGAA
GCCTGCATCAGTTTGGAGAAAGACTATCAACCTGGAATAACCTACATTGTAGTTCAGAAGAGACATCACACTCGATTATTTTGTGCTGAT
AGGACAGAAAGGGTTGGAAGAAGTGGCAATATCCCAGCTGGAACAACAGTTGATACAGACATTACACACCCATATGAGTTCGATTTTTAC
CTCTGTAGCCATGCTGGAATACAGGGTACCAGTCGTCCTTCACACTATCATGTTTTATGGGATGATAACTGCTTTACTGCAGATGAACTT
CAGCTGCTAACTTACCAGCTCTGCCACACTTACGTACGCTGTACACGATCTGTTTCTATACCTGCACCAGCGTATTATGCTCACCTGGTA
GCATTTAGAGCCAGATATCATCTTGTGGACAAAGAACATGACAGTGCTGAAGGAAGTCACGTTTCAGGACAAAGCAATGGGCGAGATCCA

>In-frame_ARHGEF2_ENST00000313695_chr1_155927504_-_AGO3_ENST00000397828_chr1_36432556_+_2130nt
ATGAAGGAAGCCAAGGATGCCCGCTATACCAATGGGCACCTCTTCACCACCATTTCAGTTTCAGGCATGACCATGTGCTATGCCTGTAAC
AAGAGCATCACAGCCAAGGAAGCCCTCATCTGCCCAACCTGCAATGTGACTATCCACAACCGCTGTAAAGACACCCTCGCCAACTGTACC
AAGGTCAAGCAGAAGCAACAGAAAGCGGCCCTGCTGAAGAACAACACCGCCTTGCAGTCCGTTTCTCTTCGAAGTAAGACAACCATCCGG
GAGCGGCCAAGCTCGGCCATCTACCCCTCCGACAGCTTCCGGCAGTCCCTCCTGGGCTCCCGCCGTGGCCGCTCCTCCTTGTCTTTAGCC
AAGAGTGTTTCTACCACCAACATTGCTGGACATTTCAATGATGAGTCTCCCCTGGGGCTGCGCCGGATCCTCTCACAGTCCACAGACTCC
CTCAACATGCGGAACCGAACCCTATCCGTGGAATCCCTCATTGACGAAGAGGTAATCTACAGTGAGCTGATGAGTGACTTTGAGATGGAT
GAGAAGGACTTTGCAGCTGACTCTTGGAGTCTTGCTGTGGACAGCAGCTTCCTGCAGCAGCATAAAAAGGAGGTGATGAAGCAGCAAGAT
GTCATCTATGAGCTAATCCAGACAGAGCTGCACCATGTGAGGACACTGAAGATCATGACCCGCCTCTTCCGCACGGGGATGCTGGAAGAG
CTACACTTGGAGCCAGGAGTGGTCCAGGGCCTGTTCCCCTGCGTGGACGAGCTCAGTGACATCCATACACGCTTCCTCAGCCAGCTATTA
GAACGCCGACGCCAGGCCCTGTGCCCTGGCAGCACCCGGAACTTTGTCATCCATCGCTTGGGTGATCTGCTCATCAGCCAGTTCTCAGGT
CCTAGTGCGGAGCAGATGTGTAAGACCTACTCGGAGTTCTGCAGCCGCCACAGCAAGGCCTTAAAGCTCTATAAGGAGCTGTACGCCCGA
GACAAACGCTTCCAGCAATTCATCCGGAAAGTGACCCGCCCCGCCGTGCTCAAGCGGCACGGGGTACAGGAGTGCATCCTGCTGGTGACT
CAGCGCATCACCAAGTACCCGTTACTCATCAGCCGCATCCTGCAGCATTCCCACGGGATCGAGGAGGAGCGCCAGGACCTGACCACAGCA
CTGGGGCTAGTGAAGGAGCTGCTGTCCAATGTGGACGAGGGTATTTATCAGCTGGAGAAAGGGGCCCGTCTGCAGGAGATCTACAACCGC
ATGGACCCTCGGGCCCAAACCCCAGTGCCTGGCAAGGGCCCCTTTGGCCGAGAGGAACTTCTGAGGCGCAAACTCATCCACGATGGCTGC
CTGCTCTGGAAGACAGCGACGGGGCGCTTCAAAGATGTGCTAGTGCTGCTGATGACAGATGTACTGGTGTTTCTCCAGGAAAAGGACCAG
AAGTACATCTTTCCTACCCTGGACAAGCCTTCAGTGGTATCGCTGCAGAATCTAATCGTACGAGACATTGCCAACCAGGAGAAAGGGATG
TTTCTGATCAGCGCAGCCCCACCTGAGATGTACGAGGTGCACACAGCATCCCGGGATGACCGGAGCACCTGGATCCGGGTCATTCAGCAG
AGCGTGCGCACGGAGGTGGTTGACTCAATGGTTCAGCATTTTAAAGTAACTATATTTGGAGACCGTAGACCAGTTTATGATGGAAAAAGA
AGTCTTTACACCGCCAATCCACTTCCTGTGGCAACTACAGGGGTAGATTTAGACGTTACTTTACCTGGGGAAGGTGGAAAAGATCGACCT
TTCAAGGTGTCAATCAAATTTGTCTCTCGGGTGAGTTGGCACCTACTGCATGAAGTACTGACAGGACGGACCTTGCCTGAGCCACTGGAA
TTAGACAAGCCAATCAGCACTAACCCTGTCCATGCCGTTGATGTGGTGCTACGACATCTGCCCTCCATGAAATACACACCTGTGGGGCGT
TCATTTTTCTCCGCTCCAGAAGGATATGACCACCCTCTGGGAGGGGGCAGGGAAGTGTGGTTTGGATTCCATCAGTCTGTTCGGCCTGCC

>In-frame_ARHGEF2_ENST00000361247_chr1_155927504_-_AGO3_ENST00000324350_chr1_36432556_+_2214nt
ATGTCTCGGATCGAATCCCTCACGCGGGCGCGGATCGACCGGAGCAGAGAGCTGGCGAGCAAGACCCGGGAAAAGGAGAAGATGAAGGAA
GCCAAGGATGCCCGCTATACCAATGGGCACCTCTTCACCACCATTTCAGTTTCAGGCATGACCATGTGCTATGCCTGTAACAAGAGCATC
ACAGCCAAGGAAGCCCTCATCTGCCCAACCTGCAATGTGACTATCCACAACCGCTGTAAAGACACCCTCGCCAACTGTACCAAGGTCAAG
CAGAAGCAACAGAAAGCGGCCCTGCTGAAGAACAACACCGCCTTGCAGTCCGTTTCTCTTCGAAGTAAGACAACCATCCGGGAGCGGCCA
AGCTCGGCCATCTACCCCTCCGACAGCTTCCGGCAGTCCCTCCTGGGCTCCCGCCGTGGCCGCTCCTCCTTGTCTTTAGCCAAGAGTGTT
TCTACCACCAACATTGCTGGACATTTCAATGATGAGTCTCCCCTGGGGCTGCGCCGGATCCTCTCACAGTCCACAGACTCCCTCAACATG
CGGAACCGAACCCTATCCGTGGAATCCCTCATTGACGAAGCAGAGGTAATCTACAGTGAGCTGATGAGTGACTTTGAGATGGATGAGAAG
GACTTTGCAGCTGACTCTTGGAGTCTTGCTGTGGACAGCAGCTTCCTGCAGCAGCATAAAAAGGAGGTGATGAAGCAGCAAGATGTCATC
TATGAGCTAATCCAGACAGAGCTGCACCATGTGAGGACACTGAAGATCATGACCCGCCTCTTCCGCACGGGGATGCTGGAAGAGCTACAC
TTGGAGCCAGGAGTGGTCCAGGGCCTGTTCCCCTGCGTGGACGAGCTCAGTGACATCCATACACGCTTCCTCAGCCAGCTATTAGAACGC
CGACGCCAGGCCCTGTGCCCTGGCAGCACCCGGAACTTTGTCATCCATCGCTTGGGTGATCTGCTCATCAGCCAGTTCTCAGGTCCTAGT
GCGGAGCAGATGTGTAAGACCTACTCGGAGTTCTGCAGCCGCCACAGCAAGGCCTTAAAGCTCTATAAGGAGCTGTACGCCCGAGACAAA
CGCTTCCAGCAATTCATCCGGAAAGTGACCCGCCCCGCCGTGCTCAAGCGGCACGGGGTACAGGAGTGCATCCTGCTGGTGACTCAGCGC
ATCACCAAGTACCCGTTACTCATCAGCCGCATCCTGCAGCATTCCCACGGGATCGAGGAGGAGCGCCAGGACCTGACCACAGCACTGGGG
CTAGTGAAGGAGCTGCTGTCCAATGTGGACGAGGGTATTTATCAGCTGGAGAAAGGGGCCCGTCTGCAGGAGATCTACAACCGCATGGAC
CCTCGGGCCCAAACCCCAGTGCCTGGCAAGGGCCCCTTTGGCCGAGAGGAACTTCTGAGGCGCAAACTCATCCACGATGGCTGCCTGCTC
TGGAAGACAGCGACGGGGCGCTTCAAAGATGTGCTAGTGCTGCTGATGACAGATGTACTGGTGTTTCTCCAGGAAAAGGACCAGAAGTAC
ATCTTTCCTACCCTGGACAAGCCTTCAGTGGTATCGCTGCAGAATCTAATCGTACGAGACATTGCCAACCAGGAGAAAGGGATGTTTCTG
ATCAGCGCAGCCCCACCTGAGATGTACGAGGTGCACACAGCATCCCGGGATGACCGGAGCACCTGGATCCGGGTCATTCAGCAGAGCGTG
CGCACGGAGGTGGTTGACTCAATGGTTCAGCATTTTAAAGTAACTATATTTGGAGACCGTAGACCAGTTTATGATGGAAAAAGAAGTCTT
TACACCGCCAATCCACTTCCTGTGGCAACTACAGGGGTAGATTTAGACGTTACTTTACCTGGGGAAGGTGGAAAAGATCGACCTTTCAAG
GTGTCAATCAAATTTGTCTCTCGGGTGAGTTGGCACCTACTGCATGAAGTACTGACAGGACGGACCTTGCCTGAGCCACTGGAATTAGAC
AAGCCAATCAGCACTAACCCTGTCCATGCCGTTGATGTGGTGCTACGACATCTGCCCTCCATGAAATACACACCTGTGGGGCGTTCATTT
TTCTCCGCTCCAGAAGGATATGACCACCCTCTGGGAGGGGGCAGGGAAGTGTGGTTTGGATTCCATCAGTCTGTTCGGCCTGCCATGTGG

>In-frame_ARHGEF2_ENST00000361247_chr1_155927504_-_AGO3_ENST00000373191_chr1_36432556_+_4107nt
ATGTCTCGGATCGAATCCCTCACGCGGGCGCGGATCGACCGGAGCAGAGAGCTGGCGAGCAAGACCCGGGAAAAGGAGAAGATGAAGGAA
GCCAAGGATGCCCGCTATACCAATGGGCACCTCTTCACCACCATTTCAGTTTCAGGCATGACCATGTGCTATGCCTGTAACAAGAGCATC
ACAGCCAAGGAAGCCCTCATCTGCCCAACCTGCAATGTGACTATCCACAACCGCTGTAAAGACACCCTCGCCAACTGTACCAAGGTCAAG
CAGAAGCAACAGAAAGCGGCCCTGCTGAAGAACAACACCGCCTTGCAGTCCGTTTCTCTTCGAAGTAAGACAACCATCCGGGAGCGGCCA
AGCTCGGCCATCTACCCCTCCGACAGCTTCCGGCAGTCCCTCCTGGGCTCCCGCCGTGGCCGCTCCTCCTTGTCTTTAGCCAAGAGTGTT
TCTACCACCAACATTGCTGGACATTTCAATGATGAGTCTCCCCTGGGGCTGCGCCGGATCCTCTCACAGTCCACAGACTCCCTCAACATG
CGGAACCGAACCCTATCCGTGGAATCCCTCATTGACGAAGCAGAGGTAATCTACAGTGAGCTGATGAGTGACTTTGAGATGGATGAGAAG
GACTTTGCAGCTGACTCTTGGAGTCTTGCTGTGGACAGCAGCTTCCTGCAGCAGCATAAAAAGGAGGTGATGAAGCAGCAAGATGTCATC
TATGAGCTAATCCAGACAGAGCTGCACCATGTGAGGACACTGAAGATCATGACCCGCCTCTTCCGCACGGGGATGCTGGAAGAGCTACAC
TTGGAGCCAGGAGTGGTCCAGGGCCTGTTCCCCTGCGTGGACGAGCTCAGTGACATCCATACACGCTTCCTCAGCCAGCTATTAGAACGC
CGACGCCAGGCCCTGTGCCCTGGCAGCACCCGGAACTTTGTCATCCATCGCTTGGGTGATCTGCTCATCAGCCAGTTCTCAGGTCCTAGT
GCGGAGCAGATGTGTAAGACCTACTCGGAGTTCTGCAGCCGCCACAGCAAGGCCTTAAAGCTCTATAAGGAGCTGTACGCCCGAGACAAA
CGCTTCCAGCAATTCATCCGGAAAGTGACCCGCCCCGCCGTGCTCAAGCGGCACGGGGTACAGGAGTGCATCCTGCTGGTGACTCAGCGC
ATCACCAAGTACCCGTTACTCATCAGCCGCATCCTGCAGCATTCCCACGGGATCGAGGAGGAGCGCCAGGACCTGACCACAGCACTGGGG
CTAGTGAAGGAGCTGCTGTCCAATGTGGACGAGGGTATTTATCAGCTGGAGAAAGGGGCCCGTCTGCAGGAGATCTACAACCGCATGGAC
CCTCGGGCCCAAACCCCAGTGCCTGGCAAGGGCCCCTTTGGCCGAGAGGAACTTCTGAGGCGCAAACTCATCCACGATGGCTGCCTGCTC
TGGAAGACAGCGACGGGGCGCTTCAAAGATGTGCTAGTGCTGCTGATGACAGATGTACTGGTGTTTCTCCAGGAAAAGGACCAGAAGTAC
ATCTTTCCTACCCTGGACAAGCCTTCAGTGGTATCGCTGCAGAATCTAATCGTACGAGACATTGCCAACCAGGAGAAAGGGATGTTTCTG
ATCAGCGCAGCCCCACCTGAGATGTACGAGGTGCACACAGCATCCCGGGATGACCGGAGCACCTGGATCCGGGTCATTCAGCAGAGCGTG
CGCACGGAGGTGGTTGACTCAATGGTTCAGCATTTTAAAGTAACTATATTTGGAGACCGTAGACCAGTTTATGATGGAAAAAGAAGTCTT
TACACCGCCAATCCACTTCCTGTGGCAACTACAGGGGTAGATTTAGACGTTACTTTACCTGGGGAAGGTGGAAAAGATCGACCTTTCAAG
GTGTCAATCAAATTTGTCTCTCGGGTGAGTTGGCACCTACTGCATGAAGTACTGACAGGACGGACCTTGCCTGAGCCACTGGAATTAGAC
AAGCCAATCAGCACTAACCCTGTCCATGCCGTTGATGTGGTGCTACGACATCTGCCCTCCATGAAATACACACCTGTGGGGCGTTCATTT
TTCTCCGCTCCAGAAGGATATGACCACCCTCTGGGAGGGGGCAGGGAAGTGTGGTTTGGATTCCATCAGTCTGTTCGGCCTGCCATGTGG
AAAATGATGCTTAATATCGATGTTTCTGCCACTGCCTTCTACAAAGCACAACCTGTAATTCAGTTCATGTGTGAAGTTCTTGATATTCAT
AATATTGATGAGCAACCAAGACCTCTGACTGATTCTCATCGGGTAAAATTCACCAAAGAGATAAAAGGTTTGAAGGTTGAAGTGACTCAT
TGTGGAACAATGAGACGGAAATACCGTGTTTGTAATGTAACAAGGAGGCCTGCCAGTCATCAAACCTTTCCTTTACAGTTAGAAAACGGC
CAAACTGTGGAGAGAACAGTAGCGCAGTATTTCAGAGAAAAGTATACTCTTCAGCTGAAGTACCCGCACCTTCCCTGTCTGCAAGTCGGG
CAGGAACAGAAACACACCTACCTGCCACTAGAAGTCTGTAATATTGTGGCAGGGCAACGATGTATCAAGAAGCTAACAGACAATCAGACT
TCCACTATGATCAAGGCAACAGCAAGATCTGCACCAGATAGACAAGAGGAAATTAGCAGATTGGTAAGAAGTGCAAATTATGAAACAGAT
CCATTTGTTCAGGAGTTTCAATTTAAAGTTCGGGATGAAATGGCTCATGTAACTGGACGCGTACTTCCAGCACCTATGCTCCAGTATGGA
GGACGGAATCGGACAGTAGCAACACCGAGCCATGGAGTATGGGACATGCGAGGGAAACAATTCCACACAGGAGTTGAAATCAAAATGTGG
GCTATCGCTTGTTTTGCCACACAGAGGCAGTGCAGAGAAGAAATATTGAAGGGTTTCACAGACCAGCTGCGTAAGATTTCTAAGGATGCA
GGGATGCCCATCCAGGGCCAGCCATGCTTCTGCAAATATGCACAGGGGGCAGACAGCGTAGAGCCCATGTTCCGGCATCTCAAGAACACA
TATTCTGGCCTACAGCTTATTATCGTCATCCTGCCGGGGAAGACACCAGTGTATGCGGAAGTGAAACGTGTAGGAGACACACTTTTGGGT
ATGGCTACACAATGTGTTCAAGTCAAGAATGTAATAAAAACATCTCCTCAAACTCTGTCAAACTTGTGCCTAAAGATAAATGTTAAACTC
GGAGGGATCAATAATATTCTTGTACCTCATCAAAGACCTTCTGTGTTCCAGCAACCAGTGATCTTTTTGGGAGCCGATGTCACTCATCCA
CCTGCTGGTGATGGAAAGAAGCCTTCTATTGCTGCTGTTGTAGGTAGTATGGATGCACACCCAAGCAGATACTGTGCCACAGTAAGAGTT
CAGAGACCCCGACAGGAGATCATCCAGGACTTGGCCTCCATGGTCCGGGAACTTCTTATTCAATTTTATAAGTCAACTCGGTTCAAGCCT
ACTCGTATCATCTTTTATCGGGATGGTGTTTCAGAGGGGCAGTTTAGGCAGGTATTATATTATGAACTACTAGCAATTCGAGAAGCCTGC
ATCAGTTTGGAGAAAGACTATCAACCTGGAATAACCTACATTGTAGTTCAGAAGAGACATCACACTCGATTATTTTGTGCTGATAGGACA
GAAAGGGTTGGAAGAAGTGGCAATATCCCAGCTGGAACAACAGTTGATACAGACATTACACACCCATATGAGTTCGATTTTTACCTCTGT
AGCCATGCTGGAATACAGGGTACCAGTCGTCCTTCACACTATCATGTTTTATGGGATGATAACTGCTTTACTGCAGATGAACTTCAGCTG
CTAACTTACCAGCTCTGCCACACTTACGTACGCTGTACACGATCTGTTTCTATACCTGCACCAGCGTATTATGCTCACCTGGTAGCATTT
AGAGCCAGATATCATCTTGTGGACAAAGAACATGACAGTGCTGAAGGAAGTCACGTTTCAGGACAAAGCAATGGGCGAGATCCACAAGCT

>In-frame_ARHGEF2_ENST00000361247_chr1_155927504_-_AGO3_ENST00000397828_chr1_36432556_+_2214nt
ATGTCTCGGATCGAATCCCTCACGCGGGCGCGGATCGACCGGAGCAGAGAGCTGGCGAGCAAGACCCGGGAAAAGGAGAAGATGAAGGAA
GCCAAGGATGCCCGCTATACCAATGGGCACCTCTTCACCACCATTTCAGTTTCAGGCATGACCATGTGCTATGCCTGTAACAAGAGCATC
ACAGCCAAGGAAGCCCTCATCTGCCCAACCTGCAATGTGACTATCCACAACCGCTGTAAAGACACCCTCGCCAACTGTACCAAGGTCAAG
CAGAAGCAACAGAAAGCGGCCCTGCTGAAGAACAACACCGCCTTGCAGTCCGTTTCTCTTCGAAGTAAGACAACCATCCGGGAGCGGCCA
AGCTCGGCCATCTACCCCTCCGACAGCTTCCGGCAGTCCCTCCTGGGCTCCCGCCGTGGCCGCTCCTCCTTGTCTTTAGCCAAGAGTGTT
TCTACCACCAACATTGCTGGACATTTCAATGATGAGTCTCCCCTGGGGCTGCGCCGGATCCTCTCACAGTCCACAGACTCCCTCAACATG
CGGAACCGAACCCTATCCGTGGAATCCCTCATTGACGAAGCAGAGGTAATCTACAGTGAGCTGATGAGTGACTTTGAGATGGATGAGAAG
GACTTTGCAGCTGACTCTTGGAGTCTTGCTGTGGACAGCAGCTTCCTGCAGCAGCATAAAAAGGAGGTGATGAAGCAGCAAGATGTCATC
TATGAGCTAATCCAGACAGAGCTGCACCATGTGAGGACACTGAAGATCATGACCCGCCTCTTCCGCACGGGGATGCTGGAAGAGCTACAC
TTGGAGCCAGGAGTGGTCCAGGGCCTGTTCCCCTGCGTGGACGAGCTCAGTGACATCCATACACGCTTCCTCAGCCAGCTATTAGAACGC
CGACGCCAGGCCCTGTGCCCTGGCAGCACCCGGAACTTTGTCATCCATCGCTTGGGTGATCTGCTCATCAGCCAGTTCTCAGGTCCTAGT
GCGGAGCAGATGTGTAAGACCTACTCGGAGTTCTGCAGCCGCCACAGCAAGGCCTTAAAGCTCTATAAGGAGCTGTACGCCCGAGACAAA
CGCTTCCAGCAATTCATCCGGAAAGTGACCCGCCCCGCCGTGCTCAAGCGGCACGGGGTACAGGAGTGCATCCTGCTGGTGACTCAGCGC
ATCACCAAGTACCCGTTACTCATCAGCCGCATCCTGCAGCATTCCCACGGGATCGAGGAGGAGCGCCAGGACCTGACCACAGCACTGGGG
CTAGTGAAGGAGCTGCTGTCCAATGTGGACGAGGGTATTTATCAGCTGGAGAAAGGGGCCCGTCTGCAGGAGATCTACAACCGCATGGAC
CCTCGGGCCCAAACCCCAGTGCCTGGCAAGGGCCCCTTTGGCCGAGAGGAACTTCTGAGGCGCAAACTCATCCACGATGGCTGCCTGCTC
TGGAAGACAGCGACGGGGCGCTTCAAAGATGTGCTAGTGCTGCTGATGACAGATGTACTGGTGTTTCTCCAGGAAAAGGACCAGAAGTAC
ATCTTTCCTACCCTGGACAAGCCTTCAGTGGTATCGCTGCAGAATCTAATCGTACGAGACATTGCCAACCAGGAGAAAGGGATGTTTCTG
ATCAGCGCAGCCCCACCTGAGATGTACGAGGTGCACACAGCATCCCGGGATGACCGGAGCACCTGGATCCGGGTCATTCAGCAGAGCGTG
CGCACGGAGGTGGTTGACTCAATGGTTCAGCATTTTAAAGTAACTATATTTGGAGACCGTAGACCAGTTTATGATGGAAAAAGAAGTCTT
TACACCGCCAATCCACTTCCTGTGGCAACTACAGGGGTAGATTTAGACGTTACTTTACCTGGGGAAGGTGGAAAAGATCGACCTTTCAAG
GTGTCAATCAAATTTGTCTCTCGGGTGAGTTGGCACCTACTGCATGAAGTACTGACAGGACGGACCTTGCCTGAGCCACTGGAATTAGAC
AAGCCAATCAGCACTAACCCTGTCCATGCCGTTGATGTGGTGCTACGACATCTGCCCTCCATGAAATACACACCTGTGGGGCGTTCATTT
TTCTCCGCTCCAGAAGGATATGACCACCCTCTGGGAGGGGGCAGGGAAGTGTGGTTTGGATTCCATCAGTCTGTTCGGCCTGCCATGTGG

>In-frame_ARHGEF2_ENST00000313667_chr1_155927504_-_AGO3_ENST00000324350_chr1_36432556_+_2211nt
ATGTCTCGGATCGAATCCCTCACGCGGGCGCGGATCGACCGGAGCAGAGAGCTGGCGAGCAAGACCCGGGAAAAGGAGAAGATGAAGGAA
GCCAAGGATGCCCGCTATACCAATGGGCACCTCTTCACCACCATTTCAGTTTCAGGCATGACCATGTGCTATGCCTGTAACAAGAGCATC
ACAGCCAAGGAAGCCCTCATCTGCCCAACCTGCAATGTGACTATCCACAACCGCTGTAAAGACACCCTCGCCAACTGTACCAAGGTCAAG
CAGAAGCAACAGAAAGCGGCCCTGCTGAAGAACAACACCGCCTTGCAGTCCGTTTCTCTTCGAAGTAAGACAACCATCCGGGAGCGGCCA
AGCTCGGCCATCTACCCCTCCGACAGCTTCCGGCAGTCCCTCCTGGGCTCCCGCCGTGGCCGCTCCTCCTTGTCTTTAGCCAAGAGTGTT
TCTACCACCAACATTGCTGGACATTTCAATGATGAGTCTCCCCTGGGGCTGCGCCGGATCCTCTCACAGTCCACAGACTCCCTCAACATG
CGGAACCGAACCCTATCCGTGGAATCCCTCATTGACGAAGAGGTAATCTACAGTGAGCTGATGAGTGACTTTGAGATGGATGAGAAGGAC
TTTGCAGCTGACTCTTGGAGTCTTGCTGTGGACAGCAGCTTCCTGCAGCAGCATAAAAAGGAGGTGATGAAGCAGCAAGATGTCATCTAT
GAGCTAATCCAGACAGAGCTGCACCATGTGAGGACACTGAAGATCATGACCCGCCTCTTCCGCACGGGGATGCTGGAAGAGCTACACTTG
GAGCCAGGAGTGGTCCAGGGCCTGTTCCCCTGCGTGGACGAGCTCAGTGACATCCATACACGCTTCCTCAGCCAGCTATTAGAACGCCGA
CGCCAGGCCCTGTGCCCTGGCAGCACCCGGAACTTTGTCATCCATCGCTTGGGTGATCTGCTCATCAGCCAGTTCTCAGGTCCTAGTGCG
GAGCAGATGTGTAAGACCTACTCGGAGTTCTGCAGCCGCCACAGCAAGGCCTTAAAGCTCTATAAGGAGCTGTACGCCCGAGACAAACGC
TTCCAGCAATTCATCCGGAAAGTGACCCGCCCCGCCGTGCTCAAGCGGCACGGGGTACAGGAGTGCATCCTGCTGGTGACTCAGCGCATC
ACCAAGTACCCGTTACTCATCAGCCGCATCCTGCAGCATTCCCACGGGATCGAGGAGGAGCGCCAGGACCTGACCACAGCACTGGGGCTA
GTGAAGGAGCTGCTGTCCAATGTGGACGAGGGTATTTATCAGCTGGAGAAAGGGGCCCGTCTGCAGGAGATCTACAACCGCATGGACCCT
CGGGCCCAAACCCCAGTGCCTGGCAAGGGCCCCTTTGGCCGAGAGGAACTTCTGAGGCGCAAACTCATCCACGATGGCTGCCTGCTCTGG
AAGACAGCGACGGGGCGCTTCAAAGATGTGCTAGTGCTGCTGATGACAGATGTACTGGTGTTTCTCCAGGAAAAGGACCAGAAGTACATC
TTTCCTACCCTGGACAAGCCTTCAGTGGTATCGCTGCAGAATCTAATCGTACGAGACATTGCCAACCAGGAGAAAGGGATGTTTCTGATC
AGCGCAGCCCCACCTGAGATGTACGAGGTGCACACAGCATCCCGGGATGACCGGAGCACCTGGATCCGGGTCATTCAGCAGAGCGTGCGC
ACGGAGGTGGTTGACTCAATGGTTCAGCATTTTAAAGTAACTATATTTGGAGACCGTAGACCAGTTTATGATGGAAAAAGAAGTCTTTAC
ACCGCCAATCCACTTCCTGTGGCAACTACAGGGGTAGATTTAGACGTTACTTTACCTGGGGAAGGTGGAAAAGATCGACCTTTCAAGGTG
TCAATCAAATTTGTCTCTCGGGTGAGTTGGCACCTACTGCATGAAGTACTGACAGGACGGACCTTGCCTGAGCCACTGGAATTAGACAAG
CCAATCAGCACTAACCCTGTCCATGCCGTTGATGTGGTGCTACGACATCTGCCCTCCATGAAATACACACCTGTGGGGCGTTCATTTTTC
TCCGCTCCAGAAGGATATGACCACCCTCTGGGAGGGGGCAGGGAAGTGTGGTTTGGATTCCATCAGTCTGTTCGGCCTGCCATGTGGAAA

>In-frame_ARHGEF2_ENST00000313667_chr1_155927504_-_AGO3_ENST00000373191_chr1_36432556_+_4104nt
ATGTCTCGGATCGAATCCCTCACGCGGGCGCGGATCGACCGGAGCAGAGAGCTGGCGAGCAAGACCCGGGAAAAGGAGAAGATGAAGGAA
GCCAAGGATGCCCGCTATACCAATGGGCACCTCTTCACCACCATTTCAGTTTCAGGCATGACCATGTGCTATGCCTGTAACAAGAGCATC
ACAGCCAAGGAAGCCCTCATCTGCCCAACCTGCAATGTGACTATCCACAACCGCTGTAAAGACACCCTCGCCAACTGTACCAAGGTCAAG
CAGAAGCAACAGAAAGCGGCCCTGCTGAAGAACAACACCGCCTTGCAGTCCGTTTCTCTTCGAAGTAAGACAACCATCCGGGAGCGGCCA
AGCTCGGCCATCTACCCCTCCGACAGCTTCCGGCAGTCCCTCCTGGGCTCCCGCCGTGGCCGCTCCTCCTTGTCTTTAGCCAAGAGTGTT
TCTACCACCAACATTGCTGGACATTTCAATGATGAGTCTCCCCTGGGGCTGCGCCGGATCCTCTCACAGTCCACAGACTCCCTCAACATG
CGGAACCGAACCCTATCCGTGGAATCCCTCATTGACGAAGAGGTAATCTACAGTGAGCTGATGAGTGACTTTGAGATGGATGAGAAGGAC
TTTGCAGCTGACTCTTGGAGTCTTGCTGTGGACAGCAGCTTCCTGCAGCAGCATAAAAAGGAGGTGATGAAGCAGCAAGATGTCATCTAT
GAGCTAATCCAGACAGAGCTGCACCATGTGAGGACACTGAAGATCATGACCCGCCTCTTCCGCACGGGGATGCTGGAAGAGCTACACTTG
GAGCCAGGAGTGGTCCAGGGCCTGTTCCCCTGCGTGGACGAGCTCAGTGACATCCATACACGCTTCCTCAGCCAGCTATTAGAACGCCGA
CGCCAGGCCCTGTGCCCTGGCAGCACCCGGAACTTTGTCATCCATCGCTTGGGTGATCTGCTCATCAGCCAGTTCTCAGGTCCTAGTGCG
GAGCAGATGTGTAAGACCTACTCGGAGTTCTGCAGCCGCCACAGCAAGGCCTTAAAGCTCTATAAGGAGCTGTACGCCCGAGACAAACGC
TTCCAGCAATTCATCCGGAAAGTGACCCGCCCCGCCGTGCTCAAGCGGCACGGGGTACAGGAGTGCATCCTGCTGGTGACTCAGCGCATC
ACCAAGTACCCGTTACTCATCAGCCGCATCCTGCAGCATTCCCACGGGATCGAGGAGGAGCGCCAGGACCTGACCACAGCACTGGGGCTA
GTGAAGGAGCTGCTGTCCAATGTGGACGAGGGTATTTATCAGCTGGAGAAAGGGGCCCGTCTGCAGGAGATCTACAACCGCATGGACCCT
CGGGCCCAAACCCCAGTGCCTGGCAAGGGCCCCTTTGGCCGAGAGGAACTTCTGAGGCGCAAACTCATCCACGATGGCTGCCTGCTCTGG
AAGACAGCGACGGGGCGCTTCAAAGATGTGCTAGTGCTGCTGATGACAGATGTACTGGTGTTTCTCCAGGAAAAGGACCAGAAGTACATC
TTTCCTACCCTGGACAAGCCTTCAGTGGTATCGCTGCAGAATCTAATCGTACGAGACATTGCCAACCAGGAGAAAGGGATGTTTCTGATC
AGCGCAGCCCCACCTGAGATGTACGAGGTGCACACAGCATCCCGGGATGACCGGAGCACCTGGATCCGGGTCATTCAGCAGAGCGTGCGC
ACGGAGGTGGTTGACTCAATGGTTCAGCATTTTAAAGTAACTATATTTGGAGACCGTAGACCAGTTTATGATGGAAAAAGAAGTCTTTAC
ACCGCCAATCCACTTCCTGTGGCAACTACAGGGGTAGATTTAGACGTTACTTTACCTGGGGAAGGTGGAAAAGATCGACCTTTCAAGGTG
TCAATCAAATTTGTCTCTCGGGTGAGTTGGCACCTACTGCATGAAGTACTGACAGGACGGACCTTGCCTGAGCCACTGGAATTAGACAAG
CCAATCAGCACTAACCCTGTCCATGCCGTTGATGTGGTGCTACGACATCTGCCCTCCATGAAATACACACCTGTGGGGCGTTCATTTTTC
TCCGCTCCAGAAGGATATGACCACCCTCTGGGAGGGGGCAGGGAAGTGTGGTTTGGATTCCATCAGTCTGTTCGGCCTGCCATGTGGAAA
ATGATGCTTAATATCGATGTTTCTGCCACTGCCTTCTACAAAGCACAACCTGTAATTCAGTTCATGTGTGAAGTTCTTGATATTCATAAT
ATTGATGAGCAACCAAGACCTCTGACTGATTCTCATCGGGTAAAATTCACCAAAGAGATAAAAGGTTTGAAGGTTGAAGTGACTCATTGT
GGAACAATGAGACGGAAATACCGTGTTTGTAATGTAACAAGGAGGCCTGCCAGTCATCAAACCTTTCCTTTACAGTTAGAAAACGGCCAA
ACTGTGGAGAGAACAGTAGCGCAGTATTTCAGAGAAAAGTATACTCTTCAGCTGAAGTACCCGCACCTTCCCTGTCTGCAAGTCGGGCAG
GAACAGAAACACACCTACCTGCCACTAGAAGTCTGTAATATTGTGGCAGGGCAACGATGTATCAAGAAGCTAACAGACAATCAGACTTCC
ACTATGATCAAGGCAACAGCAAGATCTGCACCAGATAGACAAGAGGAAATTAGCAGATTGGTAAGAAGTGCAAATTATGAAACAGATCCA
TTTGTTCAGGAGTTTCAATTTAAAGTTCGGGATGAAATGGCTCATGTAACTGGACGCGTACTTCCAGCACCTATGCTCCAGTATGGAGGA
CGGAATCGGACAGTAGCAACACCGAGCCATGGAGTATGGGACATGCGAGGGAAACAATTCCACACAGGAGTTGAAATCAAAATGTGGGCT
ATCGCTTGTTTTGCCACACAGAGGCAGTGCAGAGAAGAAATATTGAAGGGTTTCACAGACCAGCTGCGTAAGATTTCTAAGGATGCAGGG
ATGCCCATCCAGGGCCAGCCATGCTTCTGCAAATATGCACAGGGGGCAGACAGCGTAGAGCCCATGTTCCGGCATCTCAAGAACACATAT
TCTGGCCTACAGCTTATTATCGTCATCCTGCCGGGGAAGACACCAGTGTATGCGGAAGTGAAACGTGTAGGAGACACACTTTTGGGTATG
GCTACACAATGTGTTCAAGTCAAGAATGTAATAAAAACATCTCCTCAAACTCTGTCAAACTTGTGCCTAAAGATAAATGTTAAACTCGGA
GGGATCAATAATATTCTTGTACCTCATCAAAGACCTTCTGTGTTCCAGCAACCAGTGATCTTTTTGGGAGCCGATGTCACTCATCCACCT
GCTGGTGATGGAAAGAAGCCTTCTATTGCTGCTGTTGTAGGTAGTATGGATGCACACCCAAGCAGATACTGTGCCACAGTAAGAGTTCAG
AGACCCCGACAGGAGATCATCCAGGACTTGGCCTCCATGGTCCGGGAACTTCTTATTCAATTTTATAAGTCAACTCGGTTCAAGCCTACT
CGTATCATCTTTTATCGGGATGGTGTTTCAGAGGGGCAGTTTAGGCAGGTATTATATTATGAACTACTAGCAATTCGAGAAGCCTGCATC
AGTTTGGAGAAAGACTATCAACCTGGAATAACCTACATTGTAGTTCAGAAGAGACATCACACTCGATTATTTTGTGCTGATAGGACAGAA
AGGGTTGGAAGAAGTGGCAATATCCCAGCTGGAACAACAGTTGATACAGACATTACACACCCATATGAGTTCGATTTTTACCTCTGTAGC
CATGCTGGAATACAGGGTACCAGTCGTCCTTCACACTATCATGTTTTATGGGATGATAACTGCTTTACTGCAGATGAACTTCAGCTGCTA
ACTTACCAGCTCTGCCACACTTACGTACGCTGTACACGATCTGTTTCTATACCTGCACCAGCGTATTATGCTCACCTGGTAGCATTTAGA
GCCAGATATCATCTTGTGGACAAAGAACATGACAGTGCTGAAGGAAGTCACGTTTCAGGACAAAGCAATGGGCGAGATCCACAAGCTCTT

>In-frame_ARHGEF2_ENST00000313667_chr1_155927504_-_AGO3_ENST00000397828_chr1_36432556_+_2211nt
ATGTCTCGGATCGAATCCCTCACGCGGGCGCGGATCGACCGGAGCAGAGAGCTGGCGAGCAAGACCCGGGAAAAGGAGAAGATGAAGGAA
GCCAAGGATGCCCGCTATACCAATGGGCACCTCTTCACCACCATTTCAGTTTCAGGCATGACCATGTGCTATGCCTGTAACAAGAGCATC
ACAGCCAAGGAAGCCCTCATCTGCCCAACCTGCAATGTGACTATCCACAACCGCTGTAAAGACACCCTCGCCAACTGTACCAAGGTCAAG
CAGAAGCAACAGAAAGCGGCCCTGCTGAAGAACAACACCGCCTTGCAGTCCGTTTCTCTTCGAAGTAAGACAACCATCCGGGAGCGGCCA
AGCTCGGCCATCTACCCCTCCGACAGCTTCCGGCAGTCCCTCCTGGGCTCCCGCCGTGGCCGCTCCTCCTTGTCTTTAGCCAAGAGTGTT
TCTACCACCAACATTGCTGGACATTTCAATGATGAGTCTCCCCTGGGGCTGCGCCGGATCCTCTCACAGTCCACAGACTCCCTCAACATG
CGGAACCGAACCCTATCCGTGGAATCCCTCATTGACGAAGAGGTAATCTACAGTGAGCTGATGAGTGACTTTGAGATGGATGAGAAGGAC
TTTGCAGCTGACTCTTGGAGTCTTGCTGTGGACAGCAGCTTCCTGCAGCAGCATAAAAAGGAGGTGATGAAGCAGCAAGATGTCATCTAT
GAGCTAATCCAGACAGAGCTGCACCATGTGAGGACACTGAAGATCATGACCCGCCTCTTCCGCACGGGGATGCTGGAAGAGCTACACTTG
GAGCCAGGAGTGGTCCAGGGCCTGTTCCCCTGCGTGGACGAGCTCAGTGACATCCATACACGCTTCCTCAGCCAGCTATTAGAACGCCGA
CGCCAGGCCCTGTGCCCTGGCAGCACCCGGAACTTTGTCATCCATCGCTTGGGTGATCTGCTCATCAGCCAGTTCTCAGGTCCTAGTGCG
GAGCAGATGTGTAAGACCTACTCGGAGTTCTGCAGCCGCCACAGCAAGGCCTTAAAGCTCTATAAGGAGCTGTACGCCCGAGACAAACGC
TTCCAGCAATTCATCCGGAAAGTGACCCGCCCCGCCGTGCTCAAGCGGCACGGGGTACAGGAGTGCATCCTGCTGGTGACTCAGCGCATC
ACCAAGTACCCGTTACTCATCAGCCGCATCCTGCAGCATTCCCACGGGATCGAGGAGGAGCGCCAGGACCTGACCACAGCACTGGGGCTA
GTGAAGGAGCTGCTGTCCAATGTGGACGAGGGTATTTATCAGCTGGAGAAAGGGGCCCGTCTGCAGGAGATCTACAACCGCATGGACCCT
CGGGCCCAAACCCCAGTGCCTGGCAAGGGCCCCTTTGGCCGAGAGGAACTTCTGAGGCGCAAACTCATCCACGATGGCTGCCTGCTCTGG
AAGACAGCGACGGGGCGCTTCAAAGATGTGCTAGTGCTGCTGATGACAGATGTACTGGTGTTTCTCCAGGAAAAGGACCAGAAGTACATC
TTTCCTACCCTGGACAAGCCTTCAGTGGTATCGCTGCAGAATCTAATCGTACGAGACATTGCCAACCAGGAGAAAGGGATGTTTCTGATC
AGCGCAGCCCCACCTGAGATGTACGAGGTGCACACAGCATCCCGGGATGACCGGAGCACCTGGATCCGGGTCATTCAGCAGAGCGTGCGC
ACGGAGGTGGTTGACTCAATGGTTCAGCATTTTAAAGTAACTATATTTGGAGACCGTAGACCAGTTTATGATGGAAAAAGAAGTCTTTAC
ACCGCCAATCCACTTCCTGTGGCAACTACAGGGGTAGATTTAGACGTTACTTTACCTGGGGAAGGTGGAAAAGATCGACCTTTCAAGGTG
TCAATCAAATTTGTCTCTCGGGTGAGTTGGCACCTACTGCATGAAGTACTGACAGGACGGACCTTGCCTGAGCCACTGGAATTAGACAAG
CCAATCAGCACTAACCCTGTCCATGCCGTTGATGTGGTGCTACGACATCTGCCCTCCATGAAATACACACCTGTGGGGCGTTCATTTTTC
TCCGCTCCAGAAGGATATGACCACCCTCTGGGAGGGGGCAGGGAAGTGTGGTTTGGATTCCATCAGTCTGTTCGGCCTGCCATGTGGAAA


* Fusion transcript sequences (Full-length transcript).
>In-frame_ARHGEF2_ENST00000368315_chr1_155927504_-_AGO3_ENST00000324350_chr1_36432556_+_2974nt
ATGTGCTGCTGCTGTGGCTGCTGCCCGCTGCTGGCCCACCTAGAGCAGGGGTCACTTCGAGAGAGGACCCGGGAAAAGGAGAAGATGAAG
GAAGCCAAGGATGCCCGCTATACCAATGGGCACCTCTTCACCACCATTTCAGTTTCAGGCATGACCATGTGCTATGCCTGTAACAAGAGC
ATCACAGCCAAGGAAGCCCTCATCTGCCCAACCTGCAATGTGACTATCCACAACCGCTGTAAAGACACCCTCGCCAACTGTACCAAGGTC
AAGCAGAAGCAACAGAAAGCGGCCCTGCTGAAGAACAACACCGCCTTGCAGTCCGTTTCTCTTCGAAGTAAGACAACCATCCGGGAGCGG
CCAAGCTCGGCCATCTACCCCTCCGACAGCTTCCGGCAGTCCCTCCTGGGCTCCCGCCGTGGCCGCTCCTCCTTGTCTTTAGCCAAGAGT
GTTTCTACCACCAACATTGCTGGACATTTCAATGATGAGTCTCCCCTGGGGCTGCGCCGGATCCTCTCACAGTCCACAGACTCCCTCAAC
ATGCGGAACCGAACCCTATCCGTGGAATCCCTCATTGACGAAGCAGAGGTAATCTACAGTGAGCTGATGAGTGACTTTGAGATGGATGAG
AAGGACTTTGCAGCTGACTCTTGGAGTCTTGCTGTGGACAGCAGCTTCCTGCAGCAGCATAAAAAGGAGGTGATGAAGCAGCAAGATGTC
ATCTATGAGCTAATCCAGACAGAGCTGCACCATGTGAGGACACTGAAGATCATGACCCGCCTCTTCCGCACGGGGATGCTGGAAGAGCTA
CACTTGGAGCCAGGAGTGGTCCAGGGCCTGTTCCCCTGCGTGGACGAGCTCAGTGACATCCATACACGCTTCCTCAGCCAGCTATTAGAA
CGCCGACGCCAGGCCCTGTGCCCTGGCAGCACCCGGAACTTTGTCATCCATCGCTTGGGTGATCTGCTCATCAGCCAGTTCTCAGGTCCT
AGTGCGGAGCAGATGTGTAAGACCTACTCGGAGTTCTGCAGCCGCCACAGCAAGGCCTTAAAGCTCTATAAGGAGCTGTACGCCCGAGAC
AAACGCTTCCAGCAATTCATCCGGAAAGTGACCCGCCCCGCCGTGCTCAAGCGGCACGGGGTACAGGAGTGCATCCTGCTGGTGACTCAG
CGCATCACCAAGTACCCGTTACTCATCAGCCGCATCCTGCAGCATTCCCACGGGATCGAGGAGGAGCGCCAGGACCTGACCACAGCACTG
GGGCTAGTGAAGGAGCTGCTGTCCAATGTGGACGAGGGTATTTATCAGCTGGAGAAAGGGGCCCGTCTGCAGGAGATCTACAACCGCATG
GACCCTCGGGCCCAAACCCCAGTGCCTGGCAAGGGCCCCTTTGGCCGAGAGGAACTTCTGAGGCGCAAACTCATCCACGATGGCTGCCTG
CTCTGGAAGACAGCGACGGGGCGCTTCAAAGATGTGCTAGTGCTGCTGATGACAGATGTACTGGTGTTTCTCCAGGAAAAGGACCAGAAG
TACATCTTTCCTACCCTGGACAAGCCTTCAGTGGTATCGCTGCAGAATCTAATCGTACGAGACATTGCCAACCAGGAGAAAGGGATGTTT
CTGATCAGCGCAGCCCCACCTGAGATGTACGAGGTGCACACAGCATCCCGGGATGACCGGAGCACCTGGATCCGGGTCATTCAGCAGAGC
GTGCGCACGGAGGTGGTTGACTCAATGGTTCAGCATTTTAAAGTAACTATATTTGGAGACCGTAGACCAGTTTATGATGGAAAAAGAAGT
CTTTACACCGCCAATCCACTTCCTGTGGCAACTACAGGGGTAGATTTAGACGTTACTTTACCTGGGGAAGGTGGAAAAGATCGACCTTTC
AAGGTGTCAATCAAATTTGTCTCTCGGGTGAGTTGGCACCTACTGCATGAAGTACTGACAGGACGGACCTTGCCTGAGCCACTGGAATTA
GACAAGCCAATCAGCACTAACCCTGTCCATGCCGTTGATGTGGTGCTACGACATCTGCCCTCCATGAAATACACACCTGTGGGGCGTTCA
TTTTTCTCCGCTCCAGAAGGATATGACCACCCTCTGGGAGGGGGCAGGGAAGTGTGGTTTGGATTCCATCAGTCTGTTCGGCCTGCCATG
TGGAAAATGATGCTTAATATCGATGAAAGAGACCTCTGGCAGCAGTGTGGAGAATAGATAGAGGAGAAAAAACTAATCTGAGAAGCCAGT
TAGGAGGCTTTTCAATCACTAGTTCAGGTAAGAGATGGTGATGGTCTAATGTGGGATGGAGAGGAAGGATTAAGCTGAAAAAATAGGTTT
AAGAACCATGTCCAGAAAAAAAAAACTTTGGGTGTAGTACTGGTACATGGAACGGATTGGAAAAAAATAGACCAGAGCTTTACTAGATTT
TTGAAAGAATTGTTTTTGCAAATAAACTACAAGCCTGGCATATCAGTCAAGGTTCAGAACCTAGAGAAGCAGAACCAGTACGAAGTATAG
AGAGAGAGTTTATGCAATTGTAGGGGCTAGCTAGGCAAGTCTGAAATTTTGGGGGCAGGCTGTCAGGAAGGGCAGGGAAATTCAGGCATG
GGCTGAAGCAGTTATCTATAAGTGGAATTTCTTGCTCTCAGGGAAGCTTCAGCCCTACTTTTAAGACCTTTCACCTAATTGAATCAGGCC
CATCCACATTATTCAGGATAATCTCCATTACTTAAAGTCAACAGATTATGGATTTTAATTACATCTACAAAATACCTTCATAGCAACACC
TAGATTAGTGTTTGATTAAACAAATGGCAGCTGGTAGCCTAGCAAGTTAACACATTAAAAACAACACCTGCCATGATGGCTTACACTTGT
AATCCCAGCACTTTGGGAGGCCAAAGTGGGAGGATCACTTGAGATTAGGAGTTTGCGATCAGGCTGAACAACATAGTGAGACCTGATCTC

>In-frame_ARHGEF2_ENST00000368315_chr1_155927504_-_AGO3_ENST00000373191_chr1_36432556_+_20865nt
ATGTGCTGCTGCTGTGGCTGCTGCCCGCTGCTGGCCCACCTAGAGCAGGGGTCACTTCGAGAGAGGACCCGGGAAAAGGAGAAGATGAAG
GAAGCCAAGGATGCCCGCTATACCAATGGGCACCTCTTCACCACCATTTCAGTTTCAGGCATGACCATGTGCTATGCCTGTAACAAGAGC
ATCACAGCCAAGGAAGCCCTCATCTGCCCAACCTGCAATGTGACTATCCACAACCGCTGTAAAGACACCCTCGCCAACTGTACCAAGGTC
AAGCAGAAGCAACAGAAAGCGGCCCTGCTGAAGAACAACACCGCCTTGCAGTCCGTTTCTCTTCGAAGTAAGACAACCATCCGGGAGCGG
CCAAGCTCGGCCATCTACCCCTCCGACAGCTTCCGGCAGTCCCTCCTGGGCTCCCGCCGTGGCCGCTCCTCCTTGTCTTTAGCCAAGAGT
GTTTCTACCACCAACATTGCTGGACATTTCAATGATGAGTCTCCCCTGGGGCTGCGCCGGATCCTCTCACAGTCCACAGACTCCCTCAAC
ATGCGGAACCGAACCCTATCCGTGGAATCCCTCATTGACGAAGCAGAGGTAATCTACAGTGAGCTGATGAGTGACTTTGAGATGGATGAG
AAGGACTTTGCAGCTGACTCTTGGAGTCTTGCTGTGGACAGCAGCTTCCTGCAGCAGCATAAAAAGGAGGTGATGAAGCAGCAAGATGTC
ATCTATGAGCTAATCCAGACAGAGCTGCACCATGTGAGGACACTGAAGATCATGACCCGCCTCTTCCGCACGGGGATGCTGGAAGAGCTA
CACTTGGAGCCAGGAGTGGTCCAGGGCCTGTTCCCCTGCGTGGACGAGCTCAGTGACATCCATACACGCTTCCTCAGCCAGCTATTAGAA
CGCCGACGCCAGGCCCTGTGCCCTGGCAGCACCCGGAACTTTGTCATCCATCGCTTGGGTGATCTGCTCATCAGCCAGTTCTCAGGTCCT
AGTGCGGAGCAGATGTGTAAGACCTACTCGGAGTTCTGCAGCCGCCACAGCAAGGCCTTAAAGCTCTATAAGGAGCTGTACGCCCGAGAC
AAACGCTTCCAGCAATTCATCCGGAAAGTGACCCGCCCCGCCGTGCTCAAGCGGCACGGGGTACAGGAGTGCATCCTGCTGGTGACTCAG
CGCATCACCAAGTACCCGTTACTCATCAGCCGCATCCTGCAGCATTCCCACGGGATCGAGGAGGAGCGCCAGGACCTGACCACAGCACTG
GGGCTAGTGAAGGAGCTGCTGTCCAATGTGGACGAGGGTATTTATCAGCTGGAGAAAGGGGCCCGTCTGCAGGAGATCTACAACCGCATG
GACCCTCGGGCCCAAACCCCAGTGCCTGGCAAGGGCCCCTTTGGCCGAGAGGAACTTCTGAGGCGCAAACTCATCCACGATGGCTGCCTG
CTCTGGAAGACAGCGACGGGGCGCTTCAAAGATGTGCTAGTGCTGCTGATGACAGATGTACTGGTGTTTCTCCAGGAAAAGGACCAGAAG
TACATCTTTCCTACCCTGGACAAGCCTTCAGTGGTATCGCTGCAGAATCTAATCGTACGAGACATTGCCAACCAGGAGAAAGGGATGTTT
CTGATCAGCGCAGCCCCACCTGAGATGTACGAGGTGCACACAGCATCCCGGGATGACCGGAGCACCTGGATCCGGGTCATTCAGCAGAGC
GTGCGCACGGAGGTGGTTGACTCAATGGTTCAGCATTTTAAAGTAACTATATTTGGAGACCGTAGACCAGTTTATGATGGAAAAAGAAGT
CTTTACACCGCCAATCCACTTCCTGTGGCAACTACAGGGGTAGATTTAGACGTTACTTTACCTGGGGAAGGTGGAAAAGATCGACCTTTC
AAGGTGTCAATCAAATTTGTCTCTCGGGTGAGTTGGCACCTACTGCATGAAGTACTGACAGGACGGACCTTGCCTGAGCCACTGGAATTA
GACAAGCCAATCAGCACTAACCCTGTCCATGCCGTTGATGTGGTGCTACGACATCTGCCCTCCATGAAATACACACCTGTGGGGCGTTCA
TTTTTCTCCGCTCCAGAAGGATATGACCACCCTCTGGGAGGGGGCAGGGAAGTGTGGTTTGGATTCCATCAGTCTGTTCGGCCTGCCATG
TGGAAAATGATGCTTAATATCGATGTTTCTGCCACTGCCTTCTACAAAGCACAACCTGTAATTCAGTTCATGTGTGAAGTTCTTGATATT
CATAATATTGATGAGCAACCAAGACCTCTGACTGATTCTCATCGGGTAAAATTCACCAAAGAGATAAAAGGTTTGAAGGTTGAAGTGACT
CATTGTGGAACAATGAGACGGAAATACCGTGTTTGTAATGTAACAAGGAGGCCTGCCAGTCATCAAACCTTTCCTTTACAGTTAGAAAAC
GGCCAAACTGTGGAGAGAACAGTAGCGCAGTATTTCAGAGAAAAGTATACTCTTCAGCTGAAGTACCCGCACCTTCCCTGTCTGCAAGTC
GGGCAGGAACAGAAACACACCTACCTGCCACTAGAAGTCTGTAATATTGTGGCAGGGCAACGATGTATCAAGAAGCTAACAGACAATCAG
ACTTCCACTATGATCAAGGCAACAGCAAGATCTGCACCAGATAGACAAGAGGAAATTAGCAGATTGGTAAGAAGTGCAAATTATGAAACA
GATCCATTTGTTCAGGAGTTTCAATTTAAAGTTCGGGATGAAATGGCTCATGTAACTGGACGCGTACTTCCAGCACCTATGCTCCAGTAT
GGAGGACGGAATCGGACAGTAGCAACACCGAGCCATGGAGTATGGGACATGCGAGGGAAACAATTCCACACAGGAGTTGAAATCAAAATG
TGGGCTATCGCTTGTTTTGCCACACAGAGGCAGTGCAGAGAAGAAATATTGAAGGGTTTCACAGACCAGCTGCGTAAGATTTCTAAGGAT
GCAGGGATGCCCATCCAGGGCCAGCCATGCTTCTGCAAATATGCACAGGGGGCAGACAGCGTAGAGCCCATGTTCCGGCATCTCAAGAAC
ACATATTCTGGCCTACAGCTTATTATCGTCATCCTGCCGGGGAAGACACCAGTGTATGCGGAAGTGAAACGTGTAGGAGACACACTTTTG
GGTATGGCTACACAATGTGTTCAAGTCAAGAATGTAATAAAAACATCTCCTCAAACTCTGTCAAACTTGTGCCTAAAGATAAATGTTAAA
CTCGGAGGGATCAATAATATTCTTGTACCTCATCAAAGACCTTCTGTGTTCCAGCAACCAGTGATCTTTTTGGGAGCCGATGTCACTCAT
CCACCTGCTGGTGATGGAAAGAAGCCTTCTATTGCTGCTGTTGTAGGTAGTATGGATGCACACCCAAGCAGATACTGTGCCACAGTAAGA
GTTCAGAGACCCCGACAGGAGATCATCCAGGACTTGGCCTCCATGGTCCGGGAACTTCTTATTCAATTTTATAAGTCAACTCGGTTCAAG
CCTACTCGTATCATCTTTTATCGGGATGGTGTTTCAGAGGGGCAGTTTAGGCAGGTATTATATTATGAACTACTAGCAATTCGAGAAGCC
TGCATCAGTTTGGAGAAAGACTATCAACCTGGAATAACCTACATTGTAGTTCAGAAGAGACATCACACTCGATTATTTTGTGCTGATAGG
ACAGAAAGGGTTGGAAGAAGTGGCAATATCCCAGCTGGAACAACAGTTGATACAGACATTACACACCCATATGAGTTCGATTTTTACCTC
TGTAGCCATGCTGGAATACAGGGTACCAGTCGTCCTTCACACTATCATGTTTTATGGGATGATAACTGCTTTACTGCAGATGAACTTCAG
CTGCTAACTTACCAGCTCTGCCACACTTACGTACGCTGTACACGATCTGTTTCTATACCTGCACCAGCGTATTATGCTCACCTGGTAGCA
TTTAGAGCCAGATATCATCTTGTGGACAAAGAACATGACAGTGCTGAAGGAAGTCACGTTTCAGGACAAAGCAATGGGCGAGATCCACAA
GCTCTTGCCAAGGCTGTACAGATTCACCAAGATACCTTACGCACAATGTACTTCGCTTAAATAGTCCAAGTATATTCTCTGAGAGGAAGT
ACTGAAAGATGAATTGACATACAACGTATGTTTCCAGTGAAGTCAATTGAGTAAGGACACCTCCAGCCATACAGAAACCAACACTGTGTG
GGGGCCAAGGTCTGATCCTTATGTTAATACAAGGAAGATTGTTTACTTCATCAAGGAACACAGCATCATTATGCAATATGAAACCAGCCA
ACTGCTTTTTGTGCGGTCTCCTATAGGAAGTATCGCAATTGTTTTGTTTTCATTTCTTGTAGTCTAACCCTTTTAATGCCTTTACCTCAA
GTTGCTTGGCAGCACAACTATCTTTGCAAAAAAAAGTAAAGAAAAAGTAAATGATGGTTTAAAAAATACACACCTTCATGAATAATCAAA
GTGATTTTTCAGAATTATGTGTGCAAAAAATTAATGTGCATTCATATATTCTTGTAAAAGGTGTCTGTGTATTTTTAAAATATATACATC
CATACTTCATATGCATATATATCTAGATCTGGATTGATAATAGATATATATGTGTCTGTTATATATTTTAGAGTTCATTCCATTGGGGAA
TTTTCTTTCCCTTTTATTCTACCCCCACTACCGCCTTTATTTCTCTATTTCCCTTGCCTTCATCACCTACATTTTTTTCCCAGTCCTACC
AGTGACATTCAAATGTTGATGTATCTGGTTCGTTTGAATATAAAATATGGCAAACTAGAATTCTACTTTTATTTTGCATACCCTACTCCT
GACTCCTATCTCATACACAATTCTGAGTTCTCAACTCTTGATATTGCTGTCTTAAGAAACAAAATTTTATATATATATGTATACATACAT
ACACAGACACAGACACACACATATATATACATAAAATAACTTTCTGTGAGAGTGCGTCTCTCCCCTCCCACTCAGAACATACATTTACCA
TTTGCGCAATTTGTATATAAGCAGTAGCAACCTGAACTATTCTTTTTCTTTTTTCTTTTTCTTTTCTTTCTTTTTTTTTTTTAATGAGAC
AGAGCCTCGCTCTGTCACCAGGCTGGAGTGCAGTGGCGAGATCTCGGCTCACTGCAACTTCCGCCTCTCGGGTTCAAGCAATTCTCCTGC
CTCAGCCTCCCGAGTAGCTGGGTTTACAGGCATGTGCCACCACACCCAGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCGTGT
TGGCCAGGATGGTCTCGATCTCTTGACCTTGTGATCCACCCGCCTCGACCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCACCC
GGCCTACTATTCTTTTTCTTTAGTGAGTTTGTTAAAGCTGCTATAAATATAAAACCTGTCAGAAGTTGTAACTTTCTCTCTGGTAAGTGA
TGTGTATTCTGAAGCCTTCTGTTTCTATGGGTTATACATGGAAATTCTTTAAAGGTTTTATAAAGGGTAAATATTTTAAAAGATTAGAGC
TCTGTAGGGTTGAGACCTCTGAAATTGAGTAGAGAGAAGAGTTTGTTGAGGGATTTTTTTGTTTTGTTTTTTGATAGTTTACTTGCTGCC
TCTCATACCTTAATGTGATTTTCATATATTTTTTATATATATATATGTATGTGTGTGTATATAAACACATATGTATGTGTTTGGAAGTAT
AGCTTCCTTTTCTTTTATATTTATTAGAATAGTGCTTTAATAATTATAGAATTGTATTGGCAGCATCTTTTATAGAAATATAATCATGTT
TATTTTAAGAACTGACAACTTGTTTTTGCTATCTTTTAGTGCAATAAGCAGTTTTAAAGGAAAGTTGTGTCTGCATCTTTACCATGGATA
GTAGGAGGAACAGGCACCTCCATAGTTTAAAAGGGCAAAGAATACAGCCTTAATTTCAGAAGGAAAGTTTTGTAATTTTCAGTTTTAAAG
CATATCTTTTAAAATTCATCATGATAAAAGGCTGGACGCGGTGGCTCATGCCTGTAATCCTAGCACTTTGGGAGGCTGAGACAGGTATAT
CACCGGAGCTCAGGAGTTTGAGACCAGCCTGGCCAACGTGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCTGGGCGTGGTAGT
GGGCACCTCTAATCCCAGCTACTCGGGAGGCTGAGGCAGGATTGCTTGAACCTAGGAGGCGGAAGTTACAGTGAGCCAAGACTGCACCAT
TGCACTCCAGCCTGGGCAACAAAACCAAAACTCCGTCTCAAAAGAAAAAAAAATCATAATGAAAATGAAGTGAAATTGCCTAAATGAGTC
CAACTTGAATATTAGAAATAAAGTTGAACTTTTATATAATTGTGAATAGCTTAACATATTTAAATTATTTGCAAATAGATTGTGTTTATT
GAAGAATCATATTGGCTAGATGCCCATTTTCATTTACTAAAATGAATCAGGAAAATGCAAGATGATATTTTAAAACTTTTGCTAATGTAT
CACCAGTATAACTTTCCTTTTAAAATTAAGGTGATAGTAACAAAGGAAGTTAGGACTTTGATCATTTTAAATCAGTTAAATCACTGAAAC
GTGGGAAATTGTTTTACAAAACTTTTATTGATTACACTTTAAGGTATTAAAAAGTACTATAAAGCTATCAAAACTGAGTTTATCAGTAAC
ATTGGATTCAGGGGAGCTTTGCACTTTGTAACTCATGAAAATTGCATTTTGATTTTTTTTTTTTTTGCACTGGTTCAGAGTATAGATACT
ACAGATTGTTTCCAGTGGGCATTGTTGTTAGCCTTTCAGAATTCCATCTGCACGTGAAACCTAATGGATTTAGATCTTTAGTTTCTCTCT
TACCTGTAATCCACTATTATTGCCAATTCACTGTATTTTGAGCCTAAAATCTGAGCCCATGTCCTCTGACAGGCATGAAATCTTTTGTCC
CTCTGCCAGAAAACTAAGAAAGTACTGTATTTTGTATGTTTATTATTTTGAAGTGTCTGAAATGCAATTTACAACACTGTTGCAAAGAAC
TTTACAAAAGGTAATATTTGTATCGTATATACATTTTTTCTCCCAGCCTTCTCCCATCTCCTCCAGAAAAATTTCCTATAAAGATGGATT
TTTTTACACTGAAATTTTACTGAATATAGTCAGGATCATGGGCAAGAGAAGAAAATAGTATACCCAAGATGATAAAAATTTAATTCGTCT
ATGCTTGATCAGTGTGAGTAAAACATCTTCCTTTATCATGGGAGCTGCACAGATTCATGTGGGAAACTTTAGGGAATGACTGTAGATACC
CTTTCTCTATGTACTCTCTCACCTAATTTTCAGTCACTCATATATGCTAGAGTGGAGCCCTTAATTTAAATCTATTTGGAAGGACTTTTT
TAAGAGGAAAAATATTTTTTCTAAATTATAAAGCTTTACCTTTTGAGTGATTTCTTTTTTAGAGTGCTCTTACACTAGTCAGCATTGCTA
GTTTAAAGTTGATTAACTTGAAAGAGTATGTATACTATATTTCTATTTTGCTAACAAATTGGTATATTAATTACCATTGGTTCTTAATTA
CAAGAAAACTTGTGCTTAGAATTTTAAGATAAAAGGCTAAGTGACAAATGCTTCTTGAAATTTGTCCTATTTATTGTTGCATTTCTGGTG
TAGAATTTCTAATCTTTTTTATTTTAAAAAAGTTTTTTTTTTTAAGTTAAACATGAAATTCACAGTGACCCTTCTGCTCCTGCCCTTGCT
CACTAACTATATCATGAATGCTAGATTTTGGTCTTCTTTTTTCTGTGATGTATCTTACGAGACTGACTGTAAAATATCAGTCTGGCAACT
AGATAATTGATTTTCATATGAAGAAGAGTTGGGAGTTTAATGTATATTCTTGATGGTTAATGTGTCTACATAAAGTGCTGATACATGTAT
TATATCACAGTATCAGGTTACTGGCATGGAGGACCATACACTTACAATATTGTAGCTGCTATATTTATTTAAGTAGATTCTGACAGTTAC
TGCACTAAACAGTAAGGAGATAAGCAGGATTCAAGGCTAGTGTTAGACCCTTTTTTTTCCTAAGAGTAAGGACACGGAATATCAAAGTAA
CAAAGGGTGCTGCCATTTTAGTTTCAATTTAATATCAGGATATTCTTTGTTTTAGAAATGTAGATTTTGACTTTTACAGTTTGAAAAAGG
GTACCTCAGCCTCTTCAGTACTGGTTTTTTGGCACATTTCAACAGAAATATTAGATTCCCTTTCTTTTTCTTAATAGTGATCTTCTAACA
AGTTTCTTGGAAAAACTATCATTCTAAGGGAAATCCCTGTTTATAACCTATTAATATATTTCTATTCCTAGAAGAGAGTCTAGCAGGGAT
TCTAGTAGGAATTACTGAGTGTTTTGGAAGGCACTTGATAGAGGCATCTCTGCTTTCCAGCACAGGGATTCTCAGCCTTCTAAAGATCTA
GACCAGTTTCCAAGCTAGCTTCTCCACAGCCCACCACTGCCTAGTGTTTGCTTGTGTATTCTCTAATGGATTTTAGGAGGATAGGCCTTC
TGACAGAGTCATGAAAGACTGAAGGCATGTCTAGGGAAATAAAACCTGACTTGCCCTTCAGCAGGAATGACTGGCAGCGGATCTCTGTGT
TCAAGGAAAGGGTGAGCGCTAAGCATGCCAGTGATGGATCCGAAGTATTTAGATGGATTGCAGACCAGGAATTAGAGACCGTTTGTGACT
CAAGGAACTTGATGGATCTGTTTAGAGCCCTACATGAATTTGCCAAGGGCAGTGATTTTTATGAAATTCAAGAAGCAAACGACTTCGATA
CAGCTAGAATATGTTGCAGTCTTCCTATTTCAAACTTGATTTTAATATTTTTACCAAGAAGTTTAACTGACAACTCTGCAAAATTTTCAT
TCAGTATCATTAAACCTGAGTTAAATGTTTGCTTAGCTTATCCTCTTAGATGTTCTTCTGTTGAACAGGCAGGTTGCCCTTAACAGTAAC
TTGCTACTTAAATTACCTTTTATTAGTTAGTCAAGCTGCAAAAATATCATTAGTGTGGCGTCTTTATTTTGGCTTTATCCATATGAAGTA
TTCATTATTTTCATTCTTTTTGAGAATTCATAAATGTCTTAAAGCTTCAGTAAGAATTGTTGGGAGGTTTGACATCAAGTAACGCCTTCC
TGTGTAGCAGTATAACCCTAATTTAGAACTCTTGTTTTCCTATTTCAGTCCTCATATTTGATCATAGAAAAGCACTTTTGTGATTCTATA
GGAGTCAAAAAATCAGCCAAGAGTAGGTAAGTCAGTCAGCACAGAAATCAGAAAGTGAGAATTTTCTCCAAAAAATCTTTTTAAAAAAGT
CCTGCTTATACTAAGAACATTCTTGATCCGTTGCAGTGTTAGAAATGACACTGTGATTAGTGAAAGCCAAGCTGAGTCCCAGGAAGCAGG
GAGGGGGAGTGTGTGTGTGTGTATATGTATGAGTGTGTATATATATAATCTCACACACACACACAAAGGGAAAAATTATTTTGACTTTTT
TCCTACTTTTAAAATGGTACATTTAAGTTTATAATTTTCCATGTCAGTCAACATAATTTTTTAAACTAAGGTATAATGGTCAAGGCTTGT
GCTAATATTACCTACTACTCATTGAAATTTATATTACTTTACCCATCAAAACTAGTACTCCAGATGTTTACATCATTGATTAAATCTCAA
GAATCTTTTGTTCTTAAAATATGGAAGTTAAAGATTTTAATTTGAATTAAAGATAGAAGGATGGTAAATTCAATATAGAGGGTTGAGATT
TACCAGTGAGAAACCCTGTTGAAGTATCAGGTAAATGGTGTGACAAAATTAGAATCCTGTCAAATCACCTATCCAGCCATCGGGGTCCCT
TCCTTTTTTAGACTAATTTCTAAGGTAACCAGAATCTAATGTATCTATGTTAGGGTCTCAGTAAAGCAAAGACGTTTGTCAGGGCGTAGA
CTCTTGAGTTAAATTTTTTAATCATTTTTTAAAGCAAGGCGGTTCTTAGAAAGTGCCTTTTCAGAAGATGGTGCTGTAGATTTTTATTTT
TCAAGTAGCACGAAGCTAAGAATTTTAAAGATAAATTATTTTAGAACTCCAAGAGTGTGACAGTTTCATAAAAATAATGTTAGTTGTTGT
CTTGAATCTCGTCCAAGGGAACCAAGGAAAGCTTTTATGCAGTAAAGTATCTAGGTAAATGCTCACCAAATTTATTTTGTAAATTTGAAA
ACAAAATATTTAGTAGAATTACCTCTTTTAATTCCCAACTGTGTTGGAGGAAATCCATAATGCACATAAAACAGCAAACCTACTTAACTT
TTTAACAAGATTATGGGTATAGTACCAATGTCCAAAGGGAAATGTAACTTGCCTGGAATCATAGGCAACATTTTCTAATTAATCTTTTTT
TTTTTTTTTTTTTTTGAGACAAAGTCTTGCTCTGTCACCTAGGCTGGAGTGCAGTGGCTCAATCTCAGCTTACTGCAAACTCCGCCTCCC
GGGTTCAAGTGATTCTCGTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCATGCACCACCACACCCGGCCCTAATTAGTCATTATTAA
GGAGGACTGCTCATAAAGGCAGTACCAAATCATCATTCAGATCAGCTTAAGTGAGAAAGCAAAATGATAATCTCTATTGTTAGAGAAATT
TTCTTTTCTAGACACCAAGGAATATTTTAAATGATTTTTTATTTTTTCTAGGATGCAGGAACTATGAAAAATGATGACAAGGCATTTAAA
AGGGTATGATCAGTTAAATAGAAGTAGGGTCTGCAAATTGTGCTTAAGGGGAAATAAGCAAAAGAAAGGAAAATAGTAGAACCTTTCATA
CTAATTAGAAATGTAGTTACCTACCAGAGGGCAATTTTGCTCCATACCAGGAAGCAGTAAATAGCAGTAAATGATCACCTAGGCACTTCT
TTCCTGTGAATTTGGTGAGCATTCTTCCAGAAAAGAAGACTAAAAGCAAACAACAACAACAACAAAAAATACCACACCTCAGTAACCTTG
TATGCTGCATTATATAATAATGATAGTAAAATTATATTGTTTGGAGTGTACTGTGTCTGTTTGCAAATATACATGCACATTAAACTTTTT
TGTTTTTATAATGTCTTAATAGCAATTATGAGTTTATTTTTGTTAAGATTAATTTTTCTATTGTGATGTTTATATTTATTGGCAATTTGT
ATGCAACTTTTATATTTTGCTTGTCGGTTTTAAGGTATTTTATTTTTATAGATATTTCTAGCTTTCCTCATTCTTTGTAATAGCAGCAAA
GATTAAGATGGAGTGTTAATATACCAACCAAACTACGAATTCCATAAACTCTAGAGTTTGGATTTTTACCAATAAACCATTAACACTATT
TTGTAACTTAGAATATTTAATGTTGTTTATATAGTGGGCATTAAAGACAGTCTTTAGACAGATTTCTACATGTGGAGGGGAGGTGGGGCT
TTCCTGTAAGTTTGATCCTTTTTTTCCCCTTTAGTAGCAAACTAACATAACAGATTGGATTTATTTTACCTGACTACAGTTTTGGGGAAA
CCTGTCAAATAAATAATTGTTACATGCCTTTTTTTTTTAAATTTAAGCACATTGAAACTGCTTAAATGGTCACATTTTTCAGCATTAGGA
TTAAGATACCATTTTTGTAGGCCTGGAAAACAAATAGCAAATGATTCAAAATTCATTGAATTGACTTTGAAATGAAACTTTTCCCCCATA
ATTTGTTATATGGAAGATTTGCTACCCTGATCTTTTCCCTAGCATACTTCTAAAGTTGATTGAATCCCTGAGTATCAATGAAGAAATCAG
AGTTTAAGTGGCTAGGGAGAGCCAGGTATAAAGACTGATTAATAGAGTACTTCAGCTAATTAAAAATTTAAATAGTAATAATTTATGAAT
GTGAATAAATTGGAAGGCAGCAAAAAGCATGATTATAGAATATTAAGTTCAATTATATATAGACAGTCCAGTTTCCTAGTGAATAGGTCA
AGATTATTTGTTTTGTTTTGTGGCACTATCATAGTTCACTATAACTTCAAACTCCTGGGCTCAGGCTATCCTCCCACCTCAGCCTCTGAA
GTAGCTGGGACTACTCACATGCGCCACCATGCCCAGCTAATGGTTTTTTTCTTTAGAGATGGGGGTCACTATACTGCCCAGGCTGGTCTT
GAACTCCTAAGCTCAAGTGCTTCTCCCACATCAGCCTCCCAAAGTGCTGGGATTACAGCCATGAGCCACTGCATCTGGCCAAGATCAAGA
TTATGGATATTGGTATGTTAACTTTTAAAATAAAAGTACATGGGCTGGGCGCAGTGGCTAACGCCTGTAATCCCAGCAATTTGGGAGGCC
GAGGCAGGCAGACCACCTGAGGTCAGGGGTTCGTGACCAGCCTGGCCAACATGGCGAAACCCCGTCTCTACTAAACATACAAAAATTAGC
TGGGCATGGTGGCACATGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCACTTGAACTCGGGAGGCGGAGGTTGCAGTGA
GCCAAGATCGCGCCATTGCACTCCAGCCTGGGCAACAAGAGTGAAACTCCATCTCAGAAAATAAAAATAAAAATAAATAAAAGTACATGA
AAAAAGTATATTCCCTTAAGCAGGTAAAATACTTGCATTGTATTTTTACATCATGAATTTGCTTGTTAAGAAATTTCTTTTCTGTAAGTG
GTTAAAAGATAAACTGTATTCCATCCTCTGGGTTTTCAATTCTAAATTATTGGAGCTCAATGTATGACATTTTACTGTAGTGTATTCCAC
TGAGAGGCAAGGAAATGGGAAAGTGTCAGGTAATTATAAATGGGAAAATTTTATTTTTATATGATGTAAAGTTTTACAGTTTAAAATAGA
TCAGCATGTGATTTCTTGTAGAGATTAGCCATTTCATTTCTTTTTGCATTTTTGCCAGTTACATTAGTTTGCCCTATGATATACTATTCT
GAGATACTTCAGCCCCGCACACATCAAGTACTAATTGTATACAGATAGTACAGATTTGTACTCTGATTATAAGAATTTGTTACTACTAAT
TAAAAGCAAATTAATGTGGCTGGGCGTGGTAGCTCACACCTGTAATCCCAGCACTTTGGGTGGGCGGCTGAGGCGGGCGGATCACGAGGT
CAGGAGTTGGAGACCAGCCTGCCCAATATGGTGAAACCCTGTCTCTACTAAAATTACAAAAATTAGCTGGGCTTGGCGGTACGTGCCTGT
AATCCCAGCTACTGGGAAGGCCGAGGCAGGAGAATGGCTTGAACCCAGGAGGCGGAGGTTGCAGTGAGCCAAGATCACACCACTGCACTC
CAGCCTGGGCGACAGAGCAAGACTCCGTCTCAAAAAAAAAAAAAGCAAAATATTTTTGCTGTGATTGTATGTCCCCTTTTAAGGATATTT
ATTGCGCTTATAACCTTAATAGTTGTATTCATTACATTTCAACATGTCCAAGGTTAGCAGACATGTAGTTCCTGAAAACCAACATTTTAA
AAGTTGCCTCTGGGCTGGGCATGGTGGCTCACGCCTGTAATCCCTGCACTTTGGGAGGCCGAGGTGGGCGGATCACGAGGTCAAGAGATG
GAGACCATCCTGGCCAACATGCTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCTGGGTGTGGTGGCACACGCCTGTAGTCCCAGC
TACTTGGGAGGCTGAGGCAGGAGAATCACTTGAACCTGGGAGGCGGAGGTTGCAGTGAGCCAAGATTGCACCGCTGCACTCCAGCCTGGC
AACAGAGCAAGACTCCATCTCAAAACAAACATACAAACAAAAAAAGGTGCCTCTGGTCCTGTGTTTTCTTTTTCCTTCTGAAAGTTCATA
GAAACCTGGCATATAGAGCTTATTTTGCTGTTTTAACTGGTTGGCTCCACAAATCCTGCTACCTGACATCAGTACAGCTTGACCGCAGTG
AAGTACTTGATGGCTTGTTCATGTTTAGTTCACCTCTTTAGAAAGAAAGCTTTGTGGCCAGGTGCAGTGGCTCACACCTGTAATCCCAAC
ACTTTGGGCAGCTGAGGTGAGCAGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGCAAAACCCTGTCTCTTCTAAAAA
TACAAAAATTAGCCGGGTGTGGTGGCGGAGGATGCAGTGAGCCAAGATCGTGCCACTGCACTCCAGCCTGGGCAACAGAGTGAGACTCTG
TCTCAAAAAAAAAAAAAAATCGTTGTGCAGTAATAGATCATCCCAAAAAAGAATTGCCATGAACAGCGTTATGCGTAGAAAACAGATGGA
AGTGTTGGTCATTAGAGCCTTGCTTTTTAAATTTTATTCTTTCCAAAAATTGGCGGTATGCTATCTATAATTTTATGTTTGATGTTGAAG
AGGCAACACCAGAGACTAGAGAGGGAGATTACTCTGATATTTAGTGCCTAAAACTTTCATCTTGGCCGGGCACGGTGGCTCACACCTGTA
ATCCCAGCACTTCGGGAGGCCGAGGCAGGCTGATTACCTGAGGTCAGGAGTTCGAGACCAGCCTGGACAACATGGCAAAACCCGTCTCTA
CTAAAAATACAAAAATTAGCCAGGCATGGTGGTGGGCGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCGAGAGAATCGTTTGAACCCG
GTAGGCGGAGGTTGCAGTGAGCCGAGATCATGCCACTGCACTCCAGCCTGGGCGACAAGAGTGAAACTCCGTCTCAAAAAATAATAATAA
TTTTAAAAATAAAAGACAAAACTTTCATCTTTATTTCATGGCTTTATTTCATCTTTATTTCATTTTTGGTTGGGAAAACAAACAAAAATC
TCTTAAGTTAGTCCTTTAATAGTCTTTTTAGAACCAAAGAAGGAAAGACTGCAAAAATGTTGCATACGTGACTCTTTATTGTCAGAATCT
GTAGAAACTGGAGGTCTTTGTAAAGAAATAGACTAGTAGGATTGTGAGAATATATAGTGAGGGGGGATTTAGGATAAGGCTTCCTTGCTG
GGATCCTTGGACAGAAACCTTACAATTGTTTAATATTTGCAGAGTAAAAGAGCAGCTATTGCTATTTGAACCTACAGAAGAGACCTAAGA
CGAGCGTCTCTGTAATCTAAATTTATATGATAATGTTGTCCCAGACCCAAAGGCACACCTATTCTCAGTAACTTAGAGAAGTCTTGGAAG
TTGCTTCTGAATTACAGTAAAGAAATTAAATGAAGTCTTTATCCTTAAATAGGGCCAGGCATTGCTATCAACATAGTGTCTTTGGTTTTC
CCCTTTAAATAGAAAACACCAAGCAGGGCCTTTCCAGACAATGTAGTCTTTCCTGTAAAGAAAATGGTTTTGGTGTGGGATTTGGTAAAA
ACACTGGTTAGTTTGTAATGAAGAAAGAATTTTGGCATAGACAGTCCGACCCAGTTCATGGATACAGTTTGATCCCAGGGAGTTTAACAA
AAGGAAGCTTTGGTTTTGCTAGCAACAGACTTGATCTTCTATAGTAATTAATTGCAATTAAGGTTTTCCAGGAGCTTTCTCATTTCTTAG
CCCAGGGTCCAACCCCATTCCCTCTTTAAAAAAGAAAGAATAGGCCGGGAGCAGTGGCTCATGCCTGCAATCCCAGCACTTTGGGAGGCC
AAGGCAGGTGGATCACAAGGTCAGGAGTTTGAGACCAGCGTGGCCAATATGGTGAAACCCTGTCTCTACTAAAAATACAAAATTAGCTAG
GCGTGGTGGCAGGCGCCTGAGGCTGAGGCAGGAGAATCCTGCTAGTCTGAATTACAATAAGGAAATTAAATGAAGGATTTATCTTTAATA
GAGCCAGGCATTGCTATCAACATAACATGTTTGGTTTTCCCCTTTAAATAGAAAACACCAAGCAGGGCCTTTCCAGACAAGGTAGTCTGG
AACCCAGGAGGCGGAGGTTGCAGTGAGCCGAGATCCCACCATTGCACTCCAGCCTGGGTGGCAGAGTGAGACTCCGTCTCAAAAAAAAAA
AAAAGAAGGAATAGGAAAAGGACTTAGAGGCAGTTGATATAGAATTCTACTGGGGGTAAATGACACTCTCAAAATACTTGGGAAAGAAGA
ATCACATGCCACAAGCTATAGCTTGATTAATATTTTAGCATGTTTTCCATGTTTGTATTCTAAAGTTTGTTTCCTTTGACATTCCATTAT
CTTACTTACTAGAGTGCCACCATTCTTATTTGTAATACAATCAGTGTTTTATGCCATTTGTGAATCACACAATTGTTCTTTTTTCCCCAT
CACACACACTCACACACAAACACACACACTGTTAAAAATAAAAGAGGGGAAGGATAAAACAAAAATAGATAGAATGATGATTATTACAAT
GTAACTTTAACATATATGAAGAGAAATTCTAACTCAGTTAAGTGAGAATTAAGATTGAAAGTATTAATGTTGCAAGTATTATCTCTAGCC
ATGGAATTTTTTGCTGGCTATAGAATGCTAATGTGAACAGAGTATATATCAGGAATATGATGTATTATGGCACAGTGATAATATTATTGT
TGATATTAGCCAGATGTGGTGGTTTGCACCTGTAGTCCGAACTTCTCAGGAGGATGAGGCAGGAGGATAGTTGAGCCCAGGAGTTTAAAG
CAAGCCTGGGCAATACAGCAAGACCCCAATCTTTAAAATAAATAAATAAATAAGAATTATTCTTGAAAGTAATATTCTAACCTTCTGCCA
ACCAACAGAGATCCTCATATTCTTAAAGAAAATTAATATAGCTTATGGTTTTGATAAATTGGACTCTGATTTAAACTTTAAAATGTTATG
ACTTTTATTCTGATACATGGCTTCTAAAATATGTAAAAAATTATATTGAATGAATTAATACTTAACCTGTTCATTTCTCTTAATTTATGT
ATTTATTCTGACTTTATTATACAGCTTATGTCTCACATCTGCCTTCTTGATATGTGCAAAATATTGTGTAAAAATAGTTTAAAACTCATC
CCAGTTCCTAGTCAAGCGTGGGCTATAAGAGAGAAGGCTTAAGGTGTTCTTTAATGGAGGAACTTTTGAAAGATCACAAATGGAAAAAGC
CTATTGAGAATTTATTGCCTTTGAGAGTAGAAAGGGCTCTAGAATATGAGCCAGAGACTTGGAATTTAGTAATAGGTCTCCCACTGATTT
GCTCCGTGTCCTTAGGCAATTCGTTTAATCTCTGTGTGCCTAGTTTCCCCTTGTAAATAAGAGTGGTAATACCTGTCCTCACCTACCTCA
CTAAATTGTTGGAGTTCTTTTGTTCTGAGTCAGGGTCTCACTCTGTTGCCCAGGCTGAACTACAGTAGTGTGATCATAGCTCACTACAGC
CTCCAACTCCTGGGCCCAAACTATCCTCCTGCTTCAGCCTCCCAAGTAGCTGGGACTAGAGGTACATGCCACCACACCCAGCTAATTATT
TTCTTTTATTGCAGAGATGGGGTCTCACATGTTGCCAAGGCTGATCTCTAACTCCTGAGCTCAAGCAGTCCTCCTGCCTCAGCCACCCAA
AGTGCTGGGATTATAGGCATGATCACTAAATTGTTGTAAGAATAAGATAATGTTTGCGGAAGCATTTGAGTTCTCCAAAGGAAAAGCTAT
TCAGACGTTCAAGATAATAGAAGAGTGTTGTGTGAAGGATTCCTTTCCAGTTTGCCTCTGTGAAAATGTCTTTGTTGTAGATCATTTTAT
GAAATAGGAATAAGAGAAACATAGGCCTTATCATGGTGTAGTGTTCACTTACAAACATATCCTGTTGTTTCTTCCCTGCAAGATATCCAG
CACACAGGCTGAATTTTTCTTTATAATAATCCTTGGCAAAAGCATAACTTTTCAAAAACCAAATGATTTTAGTGGTGCTATGGCAGCTGC
AGTTTTGAGTTAGATTAATGTGGTGAAAACCATCAAATACTTAGAAATTGACTGGGTGCGGTGGCTCATGCCTGTAATCCCAGCACTTTG
GGAGGCCGAGGTAGGTGGATCACTTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGCAAAACCCCGTCTCTACTAAAGATACAAA
AATTAGCTGGGCACGATGGAGGGTGCCTGTAATCCCAGCTACTCGGGAGGCTAAGGTGGGAGAATTGCTTGGACCCAGGTGGCAGAGGTT
GCAGTGAGCCAAGATTGTGCCACTGCACTCCAGCCTGGGCAACAAAGCGAAGCTCTGTCTCAATAAAAAAAAAAATAATAATAATAAAAT
ACAAATACTTAGAAATTAACTTCGCCTTTGCCTTCAGGCACTTTTGCTACATGTTAGCATCAGAGGCTATTGTACAACTAGATGGTTATT
CCCTGTTTCTTGGCCGATTTTTGGTACCTTTCTTTGAAGAAGAGGGTTAGATTTTAAGAAAGAAAGTGTGCTTATTTCACTCATGTCTTT
GCAGAATTTAACTTTGCTTTACTTTAAAAATTCCAATCATCATGTACCTATAAAGGTTAAAATATAGTGAAAGTTTCTGCTTCATGTGAA
TTCAATTCTGAGCACCTGCAGGTCATATCAGGTGTCTGATGCAGTTACCTTTATAGATCGTGGCAGGTCCTTACATTTCAACAGGCTTAT
GCATTTCCATGGGGGGAAGAGATTCTGTTTCTAGGAAATTACAAAGGGCACACCACTGCAGGGAGTGTAAACAATTCTTTGTTGCAACAG
ACAAGATTTTTTTTAAAAAAAGAAAAAAGGATGCATTTTAGGTACACAGGGTATGGACGCATTCAACATTTACTTTTATCTCCACAGATG
CCAACCTCCCCTTGTTGCAGGCAGTTGGGCTTTTCCAACTCATTGCTAACAAAGCTGGCATCTGCATTAATTTCAATGAGAATTTCAAGT
ACTGAAGATGAAAAGTTGGGGAGATTCATGTTTGAAAAATGAAAAATGAACAAAAAATCCACCTTGTGCAGTGAGATAGCTAACGCTGAT
ATATCAGGAATAATTTTAAACTATTTTTGCTGTAATGTGTAGCTTTAATGTCTCTTTTCAGTTATGGACCCATAAAAGTATTCCTATATC
TTGTGAATAAAGATCATTCTTGTGGACTAGTACGTGGATGCATTCATAGGCTTTGGGAAGCAGTGGTGTGCGTATGTGTGTCTATATCAA
TATTTTATGTTTATAACTCTGCGTATTAAGTTTATATAGAAAAAAATAATGTCTTTCTTTAGTGTTTGGGGGACTCAATGGTAATATGAC
CATTGCAGTGTAATCTGACTGCTCACTCTAGAGAACACTTCTGTTATACACAATGCACATACAAACATACACCCCTAAAGCGTAGCTAAC
TGCTCCCACTAGATAATTGCTGCTAAAAACAAAACAAAACAAAACAATACAAAACAAAAAAAACCCTAAGTAATGGAGGAAGAAATAGCA
TTCTTTTAAAAGGGGCTTTTCTGAAGAGTAAAATGTAAATACAGGACATGTGGGGAGGGTGGGGCCGCCTGCAAAATGTCCTGAAGATGG
ACAAATAGCCTTTTAAATTCTACTTTTTAACCATCTTTACCGTGTGTGCCTATTTGTATTGCAGATGTGAACTACTATTTTTGGAGGTTG
ATATCAGTATGTTTTGAAACTGAATTATTACATAAAATCAGAGTAACCTCTTTCTCCATCCTCCTTTTCCACACTATTCTTGCCAAATAT
TTCTACTGAAACCCAGTTTCAGCAAGGCAAAATGATGGGACTCTCAAACCTCCCTCCTCATCTTCCCTTCCCCTCTGTCTTATGCCTGGC
CTGGCCTTTTTTGTTGTTGTTGGCTTTTCATAAGTAAGAAAAATTTATTGTAGTATTTCAAGACTGCAGAATTTCAAGTGTATATCTATA
AATCTTTTTTTAAAATCTTCGGCTACACAGTAACATCAATTAAAACAGAAGAGTGAGTCTAAGTCTGTAATATGCTGTAGGACCAGATAA
GATTTTGAATGAGACTAAACTTGACTGCCATATTTTAAGAGGAAATTGAAACTTTATGGTGGAGAATGGATGAGAGCAAGTCTATGATAT
ATATGTAGTCATTGTATAATTAGAAACACCAAATGCTGAATCCTATCACTGTGTTCTTGGGGGCCAGGCCTTGGATTTGGTTGTCATTTA
AACTCCTTGAAGATTATATGTAATTATAATGAGCAGAAGGCAAATAAAGTTTTTGAACAAAAGTCCTTGTTTTCAGTATTTAAAATTTGG
TAATATATTTTCTTTTTCAGTTAAACTATCTTCCCCACAAAAAATATTATACTTCAGTTAAACTATCTTCCCCACAGAAATTATTATACT
ACGAACAAGTTATGAGTGAGACTGAGAAGCTTGAAGAAGCTGGTTTTTAAGCAGCTCATATAATATTTTGTGTTAAAGAAAGTGTCATTG
TTTCCTGTTGGGAGGCAAATAACAACAACAACAAAAGAAATTGTCATGATTCTTTCTGAGCCAAACTGTCACGAAATGTTCTGTGACAGA
ACCACTACTCTTTTTTCTGCCATTCTGCCTACTGGAGAGTTCTATGTTGTATTTGTTTTTAATCCTTGATTTTAAAAATATTAATGGTTT

>In-frame_ARHGEF2_ENST00000368315_chr1_155927504_-_AGO3_ENST00000397828_chr1_36432556_+_2586nt
ATGTGCTGCTGCTGTGGCTGCTGCCCGCTGCTGGCCCACCTAGAGCAGGGGTCACTTCGAGAGAGGACCCGGGAAAAGGAGAAGATGAAG
GAAGCCAAGGATGCCCGCTATACCAATGGGCACCTCTTCACCACCATTTCAGTTTCAGGCATGACCATGTGCTATGCCTGTAACAAGAGC
ATCACAGCCAAGGAAGCCCTCATCTGCCCAACCTGCAATGTGACTATCCACAACCGCTGTAAAGACACCCTCGCCAACTGTACCAAGGTC
AAGCAGAAGCAACAGAAAGCGGCCCTGCTGAAGAACAACACCGCCTTGCAGTCCGTTTCTCTTCGAAGTAAGACAACCATCCGGGAGCGG
CCAAGCTCGGCCATCTACCCCTCCGACAGCTTCCGGCAGTCCCTCCTGGGCTCCCGCCGTGGCCGCTCCTCCTTGTCTTTAGCCAAGAGT
GTTTCTACCACCAACATTGCTGGACATTTCAATGATGAGTCTCCCCTGGGGCTGCGCCGGATCCTCTCACAGTCCACAGACTCCCTCAAC
ATGCGGAACCGAACCCTATCCGTGGAATCCCTCATTGACGAAGCAGAGGTAATCTACAGTGAGCTGATGAGTGACTTTGAGATGGATGAG
AAGGACTTTGCAGCTGACTCTTGGAGTCTTGCTGTGGACAGCAGCTTCCTGCAGCAGCATAAAAAGGAGGTGATGAAGCAGCAAGATGTC
ATCTATGAGCTAATCCAGACAGAGCTGCACCATGTGAGGACACTGAAGATCATGACCCGCCTCTTCCGCACGGGGATGCTGGAAGAGCTA
CACTTGGAGCCAGGAGTGGTCCAGGGCCTGTTCCCCTGCGTGGACGAGCTCAGTGACATCCATACACGCTTCCTCAGCCAGCTATTAGAA
CGCCGACGCCAGGCCCTGTGCCCTGGCAGCACCCGGAACTTTGTCATCCATCGCTTGGGTGATCTGCTCATCAGCCAGTTCTCAGGTCCT
AGTGCGGAGCAGATGTGTAAGACCTACTCGGAGTTCTGCAGCCGCCACAGCAAGGCCTTAAAGCTCTATAAGGAGCTGTACGCCCGAGAC
AAACGCTTCCAGCAATTCATCCGGAAAGTGACCCGCCCCGCCGTGCTCAAGCGGCACGGGGTACAGGAGTGCATCCTGCTGGTGACTCAG
CGCATCACCAAGTACCCGTTACTCATCAGCCGCATCCTGCAGCATTCCCACGGGATCGAGGAGGAGCGCCAGGACCTGACCACAGCACTG
GGGCTAGTGAAGGAGCTGCTGTCCAATGTGGACGAGGGTATTTATCAGCTGGAGAAAGGGGCCCGTCTGCAGGAGATCTACAACCGCATG
GACCCTCGGGCCCAAACCCCAGTGCCTGGCAAGGGCCCCTTTGGCCGAGAGGAACTTCTGAGGCGCAAACTCATCCACGATGGCTGCCTG
CTCTGGAAGACAGCGACGGGGCGCTTCAAAGATGTGCTAGTGCTGCTGATGACAGATGTACTGGTGTTTCTCCAGGAAAAGGACCAGAAG
TACATCTTTCCTACCCTGGACAAGCCTTCAGTGGTATCGCTGCAGAATCTAATCGTACGAGACATTGCCAACCAGGAGAAAGGGATGTTT
CTGATCAGCGCAGCCCCACCTGAGATGTACGAGGTGCACACAGCATCCCGGGATGACCGGAGCACCTGGATCCGGGTCATTCAGCAGAGC
GTGCGCACGGAGGTGGTTGACTCAATGGTTCAGCATTTTAAAGTAACTATATTTGGAGACCGTAGACCAGTTTATGATGGAAAAAGAAGT
CTTTACACCGCCAATCCACTTCCTGTGGCAACTACAGGGGTAGATTTAGACGTTACTTTACCTGGGGAAGGTGGAAAAGATCGACCTTTC
AAGGTGTCAATCAAATTTGTCTCTCGGGTGAGTTGGCACCTACTGCATGAAGTACTGACAGGACGGACCTTGCCTGAGCCACTGGAATTA
GACAAGCCAATCAGCACTAACCCTGTCCATGCCGTTGATGTGGTGCTACGACATCTGCCCTCCATGAAATACACACCTGTGGGGCGTTCA
TTTTTCTCCGCTCCAGAAGGATATGACCACCCTCTGGGAGGGGGCAGGGAAGTGTGGTTTGGATTCCATCAGTCTGTTCGGCCTGCCATG
TGGAAAATGATGCTTAATATCGATGAAAGAGACCTCTGGCAGCAGTGTGGAGAATAGATAGAGGAGAAAAAACTAATCTGAGAAGCCAGT
TAGGAGGCTTTTCAATCACTAGTTCAGGTTTCAGTCTACATGTTACTTCCTTGAGAAGCAGTGTTTGACACCCTTCTCCCCCAATCCAGC
CATCCCCCAAGTCTGAGTTAGGTATTTCTCTTCTGTATTCCCATAGCACAGTGTAATTCCCCTATAATAGCATGTATCACCTTGAATTAT
GGGTGTTTATTGTTCTGTCTCTCCTGTTAGAACGAAAGCTCCATGAAGGGATTGTCATTTTATTCACCAGTGTACCCTCTATGCCCAGCA

>In-frame_ARHGEF2_ENST00000313695_chr1_155927504_-_AGO3_ENST00000324350_chr1_36432556_+_2999nt
GGGATCCCGGGAGGGAGCGGAGCGGACCTGGGCTTGGTCGCCTCCAAGCCGGCGGGACCGAGTGCTTTAGGCCGCTTGAAAGAAAGTTGC
TCCGACCCGGGAAAAGGAGAAGATGAAGGAAGCCAAGGATGCCCGCTATACCAATGGGCACCTCTTCACCACCATTTCAGTTTCAGGCAT
GACCATGTGCTATGCCTGTAACAAGAGCATCACAGCCAAGGAAGCCCTCATCTGCCCAACCTGCAATGTGACTATCCACAACCGCTGTAA
AGACACCCTCGCCAACTGTACCAAGGTCAAGCAGAAGCAACAGAAAGCGGCCCTGCTGAAGAACAACACCGCCTTGCAGTCCGTTTCTCT
TCGAAGTAAGACAACCATCCGGGAGCGGCCAAGCTCGGCCATCTACCCCTCCGACAGCTTCCGGCAGTCCCTCCTGGGCTCCCGCCGTGG
CCGCTCCTCCTTGTCTTTAGCCAAGAGTGTTTCTACCACCAACATTGCTGGACATTTCAATGATGAGTCTCCCCTGGGGCTGCGCCGGAT
CCTCTCACAGTCCACAGACTCCCTCAACATGCGGAACCGAACCCTATCCGTGGAATCCCTCATTGACGAAGAGGTAATCTACAGTGAGCT
GATGAGTGACTTTGAGATGGATGAGAAGGACTTTGCAGCTGACTCTTGGAGTCTTGCTGTGGACAGCAGCTTCCTGCAGCAGCATAAAAA
GGAGGTGATGAAGCAGCAAGATGTCATCTATGAGCTAATCCAGACAGAGCTGCACCATGTGAGGACACTGAAGATCATGACCCGCCTCTT
CCGCACGGGGATGCTGGAAGAGCTACACTTGGAGCCAGGAGTGGTCCAGGGCCTGTTCCCCTGCGTGGACGAGCTCAGTGACATCCATAC
ACGCTTCCTCAGCCAGCTATTAGAACGCCGACGCCAGGCCCTGTGCCCTGGCAGCACCCGGAACTTTGTCATCCATCGCTTGGGTGATCT
GCTCATCAGCCAGTTCTCAGGTCCTAGTGCGGAGCAGATGTGTAAGACCTACTCGGAGTTCTGCAGCCGCCACAGCAAGGCCTTAAAGCT
CTATAAGGAGCTGTACGCCCGAGACAAACGCTTCCAGCAATTCATCCGGAAAGTGACCCGCCCCGCCGTGCTCAAGCGGCACGGGGTACA
GGAGTGCATCCTGCTGGTGACTCAGCGCATCACCAAGTACCCGTTACTCATCAGCCGCATCCTGCAGCATTCCCACGGGATCGAGGAGGA
GCGCCAGGACCTGACCACAGCACTGGGGCTAGTGAAGGAGCTGCTGTCCAATGTGGACGAGGGTATTTATCAGCTGGAGAAAGGGGCCCG
TCTGCAGGAGATCTACAACCGCATGGACCCTCGGGCCCAAACCCCAGTGCCTGGCAAGGGCCCCTTTGGCCGAGAGGAACTTCTGAGGCG
CAAACTCATCCACGATGGCTGCCTGCTCTGGAAGACAGCGACGGGGCGCTTCAAAGATGTGCTAGTGCTGCTGATGACAGATGTACTGGT
GTTTCTCCAGGAAAAGGACCAGAAGTACATCTTTCCTACCCTGGACAAGCCTTCAGTGGTATCGCTGCAGAATCTAATCGTACGAGACAT
TGCCAACCAGGAGAAAGGGATGTTTCTGATCAGCGCAGCCCCACCTGAGATGTACGAGGTGCACACAGCATCCCGGGATGACCGGAGCAC
CTGGATCCGGGTCATTCAGCAGAGCGTGCGCACGGAGGTGGTTGACTCAATGGTTCAGCATTTTAAAGTAACTATATTTGGAGACCGTAG
ACCAGTTTATGATGGAAAAAGAAGTCTTTACACCGCCAATCCACTTCCTGTGGCAACTACAGGGGTAGATTTAGACGTTACTTTACCTGG
GGAAGGTGGAAAAGATCGACCTTTCAAGGTGTCAATCAAATTTGTCTCTCGGGTGAGTTGGCACCTACTGCATGAAGTACTGACAGGACG
GACCTTGCCTGAGCCACTGGAATTAGACAAGCCAATCAGCACTAACCCTGTCCATGCCGTTGATGTGGTGCTACGACATCTGCCCTCCAT
GAAATACACACCTGTGGGGCGTTCATTTTTCTCCGCTCCAGAAGGATATGACCACCCTCTGGGAGGGGGCAGGGAAGTGTGGTTTGGATT
CCATCAGTCTGTTCGGCCTGCCATGTGGAAAATGATGCTTAATATCGATGAAAGAGACCTCTGGCAGCAGTGTGGAGAATAGATAGAGGA
GAAAAAACTAATCTGAGAAGCCAGTTAGGAGGCTTTTCAATCACTAGTTCAGGTAAGAGATGGTGATGGTCTAATGTGGGATGGAGAGGA
AGGATTAAGCTGAAAAAATAGGTTTAAGAACCATGTCCAGAAAAAAAAAACTTTGGGTGTAGTACTGGTACATGGAACGGATTGGAAAAA
AATAGACCAGAGCTTTACTAGATTTTTGAAAGAATTGTTTTTGCAAATAAACTACAAGCCTGGCATATCAGTCAAGGTTCAGAACCTAGA
GAAGCAGAACCAGTACGAAGTATAGAGAGAGAGTTTATGCAATTGTAGGGGCTAGCTAGGCAAGTCTGAAATTTTGGGGGCAGGCTGTCA
GGAAGGGCAGGGAAATTCAGGCATGGGCTGAAGCAGTTATCTATAAGTGGAATTTCTTGCTCTCAGGGAAGCTTCAGCCCTACTTTTAAG
ACCTTTCACCTAATTGAATCAGGCCCATCCACATTATTCAGGATAATCTCCATTACTTAAAGTCAACAGATTATGGATTTTAATTACATC
TACAAAATACCTTCATAGCAACACCTAGATTAGTGTTTGATTAAACAAATGGCAGCTGGTAGCCTAGCAAGTTAACACATTAAAAACAAC
ACCTGCCATGATGGCTTACACTTGTAATCCCAGCACTTTGGGAGGCCAAAGTGGGAGGATCACTTGAGATTAGGAGTTTGCGATCAGGCT

>In-frame_ARHGEF2_ENST00000313695_chr1_155927504_-_AGO3_ENST00000373191_chr1_36432556_+_20890nt
GGGATCCCGGGAGGGAGCGGAGCGGACCTGGGCTTGGTCGCCTCCAAGCCGGCGGGACCGAGTGCTTTAGGCCGCTTGAAAGAAAGTTGC
TCCGACCCGGGAAAAGGAGAAGATGAAGGAAGCCAAGGATGCCCGCTATACCAATGGGCACCTCTTCACCACCATTTCAGTTTCAGGCAT
GACCATGTGCTATGCCTGTAACAAGAGCATCACAGCCAAGGAAGCCCTCATCTGCCCAACCTGCAATGTGACTATCCACAACCGCTGTAA
AGACACCCTCGCCAACTGTACCAAGGTCAAGCAGAAGCAACAGAAAGCGGCCCTGCTGAAGAACAACACCGCCTTGCAGTCCGTTTCTCT
TCGAAGTAAGACAACCATCCGGGAGCGGCCAAGCTCGGCCATCTACCCCTCCGACAGCTTCCGGCAGTCCCTCCTGGGCTCCCGCCGTGG
CCGCTCCTCCTTGTCTTTAGCCAAGAGTGTTTCTACCACCAACATTGCTGGACATTTCAATGATGAGTCTCCCCTGGGGCTGCGCCGGAT
CCTCTCACAGTCCACAGACTCCCTCAACATGCGGAACCGAACCCTATCCGTGGAATCCCTCATTGACGAAGAGGTAATCTACAGTGAGCT
GATGAGTGACTTTGAGATGGATGAGAAGGACTTTGCAGCTGACTCTTGGAGTCTTGCTGTGGACAGCAGCTTCCTGCAGCAGCATAAAAA
GGAGGTGATGAAGCAGCAAGATGTCATCTATGAGCTAATCCAGACAGAGCTGCACCATGTGAGGACACTGAAGATCATGACCCGCCTCTT
CCGCACGGGGATGCTGGAAGAGCTACACTTGGAGCCAGGAGTGGTCCAGGGCCTGTTCCCCTGCGTGGACGAGCTCAGTGACATCCATAC
ACGCTTCCTCAGCCAGCTATTAGAACGCCGACGCCAGGCCCTGTGCCCTGGCAGCACCCGGAACTTTGTCATCCATCGCTTGGGTGATCT
GCTCATCAGCCAGTTCTCAGGTCCTAGTGCGGAGCAGATGTGTAAGACCTACTCGGAGTTCTGCAGCCGCCACAGCAAGGCCTTAAAGCT
CTATAAGGAGCTGTACGCCCGAGACAAACGCTTCCAGCAATTCATCCGGAAAGTGACCCGCCCCGCCGTGCTCAAGCGGCACGGGGTACA
GGAGTGCATCCTGCTGGTGACTCAGCGCATCACCAAGTACCCGTTACTCATCAGCCGCATCCTGCAGCATTCCCACGGGATCGAGGAGGA
GCGCCAGGACCTGACCACAGCACTGGGGCTAGTGAAGGAGCTGCTGTCCAATGTGGACGAGGGTATTTATCAGCTGGAGAAAGGGGCCCG
TCTGCAGGAGATCTACAACCGCATGGACCCTCGGGCCCAAACCCCAGTGCCTGGCAAGGGCCCCTTTGGCCGAGAGGAACTTCTGAGGCG
CAAACTCATCCACGATGGCTGCCTGCTCTGGAAGACAGCGACGGGGCGCTTCAAAGATGTGCTAGTGCTGCTGATGACAGATGTACTGGT
GTTTCTCCAGGAAAAGGACCAGAAGTACATCTTTCCTACCCTGGACAAGCCTTCAGTGGTATCGCTGCAGAATCTAATCGTACGAGACAT
TGCCAACCAGGAGAAAGGGATGTTTCTGATCAGCGCAGCCCCACCTGAGATGTACGAGGTGCACACAGCATCCCGGGATGACCGGAGCAC
CTGGATCCGGGTCATTCAGCAGAGCGTGCGCACGGAGGTGGTTGACTCAATGGTTCAGCATTTTAAAGTAACTATATTTGGAGACCGTAG
ACCAGTTTATGATGGAAAAAGAAGTCTTTACACCGCCAATCCACTTCCTGTGGCAACTACAGGGGTAGATTTAGACGTTACTTTACCTGG
GGAAGGTGGAAAAGATCGACCTTTCAAGGTGTCAATCAAATTTGTCTCTCGGGTGAGTTGGCACCTACTGCATGAAGTACTGACAGGACG
GACCTTGCCTGAGCCACTGGAATTAGACAAGCCAATCAGCACTAACCCTGTCCATGCCGTTGATGTGGTGCTACGACATCTGCCCTCCAT
GAAATACACACCTGTGGGGCGTTCATTTTTCTCCGCTCCAGAAGGATATGACCACCCTCTGGGAGGGGGCAGGGAAGTGTGGTTTGGATT
CCATCAGTCTGTTCGGCCTGCCATGTGGAAAATGATGCTTAATATCGATGTTTCTGCCACTGCCTTCTACAAAGCACAACCTGTAATTCA
GTTCATGTGTGAAGTTCTTGATATTCATAATATTGATGAGCAACCAAGACCTCTGACTGATTCTCATCGGGTAAAATTCACCAAAGAGAT
AAAAGGTTTGAAGGTTGAAGTGACTCATTGTGGAACAATGAGACGGAAATACCGTGTTTGTAATGTAACAAGGAGGCCTGCCAGTCATCA
AACCTTTCCTTTACAGTTAGAAAACGGCCAAACTGTGGAGAGAACAGTAGCGCAGTATTTCAGAGAAAAGTATACTCTTCAGCTGAAGTA
CCCGCACCTTCCCTGTCTGCAAGTCGGGCAGGAACAGAAACACACCTACCTGCCACTAGAAGTCTGTAATATTGTGGCAGGGCAACGATG
TATCAAGAAGCTAACAGACAATCAGACTTCCACTATGATCAAGGCAACAGCAAGATCTGCACCAGATAGACAAGAGGAAATTAGCAGATT
GGTAAGAAGTGCAAATTATGAAACAGATCCATTTGTTCAGGAGTTTCAATTTAAAGTTCGGGATGAAATGGCTCATGTAACTGGACGCGT
ACTTCCAGCACCTATGCTCCAGTATGGAGGACGGAATCGGACAGTAGCAACACCGAGCCATGGAGTATGGGACATGCGAGGGAAACAATT
CCACACAGGAGTTGAAATCAAAATGTGGGCTATCGCTTGTTTTGCCACACAGAGGCAGTGCAGAGAAGAAATATTGAAGGGTTTCACAGA
CCAGCTGCGTAAGATTTCTAAGGATGCAGGGATGCCCATCCAGGGCCAGCCATGCTTCTGCAAATATGCACAGGGGGCAGACAGCGTAGA
GCCCATGTTCCGGCATCTCAAGAACACATATTCTGGCCTACAGCTTATTATCGTCATCCTGCCGGGGAAGACACCAGTGTATGCGGAAGT
GAAACGTGTAGGAGACACACTTTTGGGTATGGCTACACAATGTGTTCAAGTCAAGAATGTAATAAAAACATCTCCTCAAACTCTGTCAAA
CTTGTGCCTAAAGATAAATGTTAAACTCGGAGGGATCAATAATATTCTTGTACCTCATCAAAGACCTTCTGTGTTCCAGCAACCAGTGAT
CTTTTTGGGAGCCGATGTCACTCATCCACCTGCTGGTGATGGAAAGAAGCCTTCTATTGCTGCTGTTGTAGGTAGTATGGATGCACACCC
AAGCAGATACTGTGCCACAGTAAGAGTTCAGAGACCCCGACAGGAGATCATCCAGGACTTGGCCTCCATGGTCCGGGAACTTCTTATTCA
ATTTTATAAGTCAACTCGGTTCAAGCCTACTCGTATCATCTTTTATCGGGATGGTGTTTCAGAGGGGCAGTTTAGGCAGGTATTATATTA
TGAACTACTAGCAATTCGAGAAGCCTGCATCAGTTTGGAGAAAGACTATCAACCTGGAATAACCTACATTGTAGTTCAGAAGAGACATCA
CACTCGATTATTTTGTGCTGATAGGACAGAAAGGGTTGGAAGAAGTGGCAATATCCCAGCTGGAACAACAGTTGATACAGACATTACACA
CCCATATGAGTTCGATTTTTACCTCTGTAGCCATGCTGGAATACAGGGTACCAGTCGTCCTTCACACTATCATGTTTTATGGGATGATAA
CTGCTTTACTGCAGATGAACTTCAGCTGCTAACTTACCAGCTCTGCCACACTTACGTACGCTGTACACGATCTGTTTCTATACCTGCACC
AGCGTATTATGCTCACCTGGTAGCATTTAGAGCCAGATATCATCTTGTGGACAAAGAACATGACAGTGCTGAAGGAAGTCACGTTTCAGG
ACAAAGCAATGGGCGAGATCCACAAGCTCTTGCCAAGGCTGTACAGATTCACCAAGATACCTTACGCACAATGTACTTCGCTTAAATAGT
CCAAGTATATTCTCTGAGAGGAAGTACTGAAAGATGAATTGACATACAACGTATGTTTCCAGTGAAGTCAATTGAGTAAGGACACCTCCA
GCCATACAGAAACCAACACTGTGTGGGGGCCAAGGTCTGATCCTTATGTTAATACAAGGAAGATTGTTTACTTCATCAAGGAACACAGCA
TCATTATGCAATATGAAACCAGCCAACTGCTTTTTGTGCGGTCTCCTATAGGAAGTATCGCAATTGTTTTGTTTTCATTTCTTGTAGTCT
AACCCTTTTAATGCCTTTACCTCAAGTTGCTTGGCAGCACAACTATCTTTGCAAAAAAAAGTAAAGAAAAAGTAAATGATGGTTTAAAAA
ATACACACCTTCATGAATAATCAAAGTGATTTTTCAGAATTATGTGTGCAAAAAATTAATGTGCATTCATATATTCTTGTAAAAGGTGTC
TGTGTATTTTTAAAATATATACATCCATACTTCATATGCATATATATCTAGATCTGGATTGATAATAGATATATATGTGTCTGTTATATA
TTTTAGAGTTCATTCCATTGGGGAATTTTCTTTCCCTTTTATTCTACCCCCACTACCGCCTTTATTTCTCTATTTCCCTTGCCTTCATCA
CCTACATTTTTTTCCCAGTCCTACCAGTGACATTCAAATGTTGATGTATCTGGTTCGTTTGAATATAAAATATGGCAAACTAGAATTCTA
CTTTTATTTTGCATACCCTACTCCTGACTCCTATCTCATACACAATTCTGAGTTCTCAACTCTTGATATTGCTGTCTTAAGAAACAAAAT
TTTATATATATATGTATACATACATACACAGACACAGACACACACATATATATACATAAAATAACTTTCTGTGAGAGTGCGTCTCTCCCC
TCCCACTCAGAACATACATTTACCATTTGCGCAATTTGTATATAAGCAGTAGCAACCTGAACTATTCTTTTTCTTTTTTCTTTTTCTTTT
CTTTCTTTTTTTTTTTTAATGAGACAGAGCCTCGCTCTGTCACCAGGCTGGAGTGCAGTGGCGAGATCTCGGCTCACTGCAACTTCCGCC
TCTCGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGTTTACAGGCATGTGCCACCACACCCAGCTAATTTTTGTATTTT
TAGTAGAGACGGGGTTTCACCGTGTTGGCCAGGATGGTCTCGATCTCTTGACCTTGTGATCCACCCGCCTCGACCTCCCAAAGTGCTGGG
ATTACAGGCATGAGCCACCGCACCCGGCCTACTATTCTTTTTCTTTAGTGAGTTTGTTAAAGCTGCTATAAATATAAAACCTGTCAGAAG
TTGTAACTTTCTCTCTGGTAAGTGATGTGTATTCTGAAGCCTTCTGTTTCTATGGGTTATACATGGAAATTCTTTAAAGGTTTTATAAAG
GGTAAATATTTTAAAAGATTAGAGCTCTGTAGGGTTGAGACCTCTGAAATTGAGTAGAGAGAAGAGTTTGTTGAGGGATTTTTTTGTTTT
GTTTTTTGATAGTTTACTTGCTGCCTCTCATACCTTAATGTGATTTTCATATATTTTTTATATATATATATGTATGTGTGTGTATATAAA
CACATATGTATGTGTTTGGAAGTATAGCTTCCTTTTCTTTTATATTTATTAGAATAGTGCTTTAATAATTATAGAATTGTATTGGCAGCA
TCTTTTATAGAAATATAATCATGTTTATTTTAAGAACTGACAACTTGTTTTTGCTATCTTTTAGTGCAATAAGCAGTTTTAAAGGAAAGT
TGTGTCTGCATCTTTACCATGGATAGTAGGAGGAACAGGCACCTCCATAGTTTAAAAGGGCAAAGAATACAGCCTTAATTTCAGAAGGAA
AGTTTTGTAATTTTCAGTTTTAAAGCATATCTTTTAAAATTCATCATGATAAAAGGCTGGACGCGGTGGCTCATGCCTGTAATCCTAGCA
CTTTGGGAGGCTGAGACAGGTATATCACCGGAGCTCAGGAGTTTGAGACCAGCCTGGCCAACGTGGTGAAACCCCGTCTCTACTAAAAAT
ACAAAAATTAGCTGGGCGTGGTAGTGGGCACCTCTAATCCCAGCTACTCGGGAGGCTGAGGCAGGATTGCTTGAACCTAGGAGGCGGAAG
TTACAGTGAGCCAAGACTGCACCATTGCACTCCAGCCTGGGCAACAAAACCAAAACTCCGTCTCAAAAGAAAAAAAAATCATAATGAAAA
TGAAGTGAAATTGCCTAAATGAGTCCAACTTGAATATTAGAAATAAAGTTGAACTTTTATATAATTGTGAATAGCTTAACATATTTAAAT
TATTTGCAAATAGATTGTGTTTATTGAAGAATCATATTGGCTAGATGCCCATTTTCATTTACTAAAATGAATCAGGAAAATGCAAGATGA
TATTTTAAAACTTTTGCTAATGTATCACCAGTATAACTTTCCTTTTAAAATTAAGGTGATAGTAACAAAGGAAGTTAGGACTTTGATCAT
TTTAAATCAGTTAAATCACTGAAACGTGGGAAATTGTTTTACAAAACTTTTATTGATTACACTTTAAGGTATTAAAAAGTACTATAAAGC
TATCAAAACTGAGTTTATCAGTAACATTGGATTCAGGGGAGCTTTGCACTTTGTAACTCATGAAAATTGCATTTTGATTTTTTTTTTTTT
TGCACTGGTTCAGAGTATAGATACTACAGATTGTTTCCAGTGGGCATTGTTGTTAGCCTTTCAGAATTCCATCTGCACGTGAAACCTAAT
GGATTTAGATCTTTAGTTTCTCTCTTACCTGTAATCCACTATTATTGCCAATTCACTGTATTTTGAGCCTAAAATCTGAGCCCATGTCCT
CTGACAGGCATGAAATCTTTTGTCCCTCTGCCAGAAAACTAAGAAAGTACTGTATTTTGTATGTTTATTATTTTGAAGTGTCTGAAATGC
AATTTACAACACTGTTGCAAAGAACTTTACAAAAGGTAATATTTGTATCGTATATACATTTTTTCTCCCAGCCTTCTCCCATCTCCTCCA
GAAAAATTTCCTATAAAGATGGATTTTTTTACACTGAAATTTTACTGAATATAGTCAGGATCATGGGCAAGAGAAGAAAATAGTATACCC
AAGATGATAAAAATTTAATTCGTCTATGCTTGATCAGTGTGAGTAAAACATCTTCCTTTATCATGGGAGCTGCACAGATTCATGTGGGAA
ACTTTAGGGAATGACTGTAGATACCCTTTCTCTATGTACTCTCTCACCTAATTTTCAGTCACTCATATATGCTAGAGTGGAGCCCTTAAT
TTAAATCTATTTGGAAGGACTTTTTTAAGAGGAAAAATATTTTTTCTAAATTATAAAGCTTTACCTTTTGAGTGATTTCTTTTTTAGAGT
GCTCTTACACTAGTCAGCATTGCTAGTTTAAAGTTGATTAACTTGAAAGAGTATGTATACTATATTTCTATTTTGCTAACAAATTGGTAT
ATTAATTACCATTGGTTCTTAATTACAAGAAAACTTGTGCTTAGAATTTTAAGATAAAAGGCTAAGTGACAAATGCTTCTTGAAATTTGT
CCTATTTATTGTTGCATTTCTGGTGTAGAATTTCTAATCTTTTTTATTTTAAAAAAGTTTTTTTTTTTAAGTTAAACATGAAATTCACAG
TGACCCTTCTGCTCCTGCCCTTGCTCACTAACTATATCATGAATGCTAGATTTTGGTCTTCTTTTTTCTGTGATGTATCTTACGAGACTG
ACTGTAAAATATCAGTCTGGCAACTAGATAATTGATTTTCATATGAAGAAGAGTTGGGAGTTTAATGTATATTCTTGATGGTTAATGTGT
CTACATAAAGTGCTGATACATGTATTATATCACAGTATCAGGTTACTGGCATGGAGGACCATACACTTACAATATTGTAGCTGCTATATT
TATTTAAGTAGATTCTGACAGTTACTGCACTAAACAGTAAGGAGATAAGCAGGATTCAAGGCTAGTGTTAGACCCTTTTTTTTCCTAAGA
GTAAGGACACGGAATATCAAAGTAACAAAGGGTGCTGCCATTTTAGTTTCAATTTAATATCAGGATATTCTTTGTTTTAGAAATGTAGAT
TTTGACTTTTACAGTTTGAAAAAGGGTACCTCAGCCTCTTCAGTACTGGTTTTTTGGCACATTTCAACAGAAATATTAGATTCCCTTTCT
TTTTCTTAATAGTGATCTTCTAACAAGTTTCTTGGAAAAACTATCATTCTAAGGGAAATCCCTGTTTATAACCTATTAATATATTTCTAT
TCCTAGAAGAGAGTCTAGCAGGGATTCTAGTAGGAATTACTGAGTGTTTTGGAAGGCACTTGATAGAGGCATCTCTGCTTTCCAGCACAG
GGATTCTCAGCCTTCTAAAGATCTAGACCAGTTTCCAAGCTAGCTTCTCCACAGCCCACCACTGCCTAGTGTTTGCTTGTGTATTCTCTA
ATGGATTTTAGGAGGATAGGCCTTCTGACAGAGTCATGAAAGACTGAAGGCATGTCTAGGGAAATAAAACCTGACTTGCCCTTCAGCAGG
AATGACTGGCAGCGGATCTCTGTGTTCAAGGAAAGGGTGAGCGCTAAGCATGCCAGTGATGGATCCGAAGTATTTAGATGGATTGCAGAC
CAGGAATTAGAGACCGTTTGTGACTCAAGGAACTTGATGGATCTGTTTAGAGCCCTACATGAATTTGCCAAGGGCAGTGATTTTTATGAA
ATTCAAGAAGCAAACGACTTCGATACAGCTAGAATATGTTGCAGTCTTCCTATTTCAAACTTGATTTTAATATTTTTACCAAGAAGTTTA
ACTGACAACTCTGCAAAATTTTCATTCAGTATCATTAAACCTGAGTTAAATGTTTGCTTAGCTTATCCTCTTAGATGTTCTTCTGTTGAA
CAGGCAGGTTGCCCTTAACAGTAACTTGCTACTTAAATTACCTTTTATTAGTTAGTCAAGCTGCAAAAATATCATTAGTGTGGCGTCTTT
ATTTTGGCTTTATCCATATGAAGTATTCATTATTTTCATTCTTTTTGAGAATTCATAAATGTCTTAAAGCTTCAGTAAGAATTGTTGGGA
GGTTTGACATCAAGTAACGCCTTCCTGTGTAGCAGTATAACCCTAATTTAGAACTCTTGTTTTCCTATTTCAGTCCTCATATTTGATCAT
AGAAAAGCACTTTTGTGATTCTATAGGAGTCAAAAAATCAGCCAAGAGTAGGTAAGTCAGTCAGCACAGAAATCAGAAAGTGAGAATTTT
CTCCAAAAAATCTTTTTAAAAAAGTCCTGCTTATACTAAGAACATTCTTGATCCGTTGCAGTGTTAGAAATGACACTGTGATTAGTGAAA
GCCAAGCTGAGTCCCAGGAAGCAGGGAGGGGGAGTGTGTGTGTGTGTATATGTATGAGTGTGTATATATATAATCTCACACACACACACA
AAGGGAAAAATTATTTTGACTTTTTTCCTACTTTTAAAATGGTACATTTAAGTTTATAATTTTCCATGTCAGTCAACATAATTTTTTAAA
CTAAGGTATAATGGTCAAGGCTTGTGCTAATATTACCTACTACTCATTGAAATTTATATTACTTTACCCATCAAAACTAGTACTCCAGAT
GTTTACATCATTGATTAAATCTCAAGAATCTTTTGTTCTTAAAATATGGAAGTTAAAGATTTTAATTTGAATTAAAGATAGAAGGATGGT
AAATTCAATATAGAGGGTTGAGATTTACCAGTGAGAAACCCTGTTGAAGTATCAGGTAAATGGTGTGACAAAATTAGAATCCTGTCAAAT
CACCTATCCAGCCATCGGGGTCCCTTCCTTTTTTAGACTAATTTCTAAGGTAACCAGAATCTAATGTATCTATGTTAGGGTCTCAGTAAA
GCAAAGACGTTTGTCAGGGCGTAGACTCTTGAGTTAAATTTTTTAATCATTTTTTAAAGCAAGGCGGTTCTTAGAAAGTGCCTTTTCAGA
AGATGGTGCTGTAGATTTTTATTTTTCAAGTAGCACGAAGCTAAGAATTTTAAAGATAAATTATTTTAGAACTCCAAGAGTGTGACAGTT
TCATAAAAATAATGTTAGTTGTTGTCTTGAATCTCGTCCAAGGGAACCAAGGAAAGCTTTTATGCAGTAAAGTATCTAGGTAAATGCTCA
CCAAATTTATTTTGTAAATTTGAAAACAAAATATTTAGTAGAATTACCTCTTTTAATTCCCAACTGTGTTGGAGGAAATCCATAATGCAC
ATAAAACAGCAAACCTACTTAACTTTTTAACAAGATTATGGGTATAGTACCAATGTCCAAAGGGAAATGTAACTTGCCTGGAATCATAGG
CAACATTTTCTAATTAATCTTTTTTTTTTTTTTTTTTTTTGAGACAAAGTCTTGCTCTGTCACCTAGGCTGGAGTGCAGTGGCTCAATCT
CAGCTTACTGCAAACTCCGCCTCCCGGGTTCAAGTGATTCTCGTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCATGCACCACCACA
CCCGGCCCTAATTAGTCATTATTAAGGAGGACTGCTCATAAAGGCAGTACCAAATCATCATTCAGATCAGCTTAAGTGAGAAAGCAAAAT
GATAATCTCTATTGTTAGAGAAATTTTCTTTTCTAGACACCAAGGAATATTTTAAATGATTTTTTATTTTTTCTAGGATGCAGGAACTAT
GAAAAATGATGACAAGGCATTTAAAAGGGTATGATCAGTTAAATAGAAGTAGGGTCTGCAAATTGTGCTTAAGGGGAAATAAGCAAAAGA
AAGGAAAATAGTAGAACCTTTCATACTAATTAGAAATGTAGTTACCTACCAGAGGGCAATTTTGCTCCATACCAGGAAGCAGTAAATAGC
AGTAAATGATCACCTAGGCACTTCTTTCCTGTGAATTTGGTGAGCATTCTTCCAGAAAAGAAGACTAAAAGCAAACAACAACAACAACAA
AAAATACCACACCTCAGTAACCTTGTATGCTGCATTATATAATAATGATAGTAAAATTATATTGTTTGGAGTGTACTGTGTCTGTTTGCA
AATATACATGCACATTAAACTTTTTTGTTTTTATAATGTCTTAATAGCAATTATGAGTTTATTTTTGTTAAGATTAATTTTTCTATTGTG
ATGTTTATATTTATTGGCAATTTGTATGCAACTTTTATATTTTGCTTGTCGGTTTTAAGGTATTTTATTTTTATAGATATTTCTAGCTTT
CCTCATTCTTTGTAATAGCAGCAAAGATTAAGATGGAGTGTTAATATACCAACCAAACTACGAATTCCATAAACTCTAGAGTTTGGATTT
TTACCAATAAACCATTAACACTATTTTGTAACTTAGAATATTTAATGTTGTTTATATAGTGGGCATTAAAGACAGTCTTTAGACAGATTT
CTACATGTGGAGGGGAGGTGGGGCTTTCCTGTAAGTTTGATCCTTTTTTTCCCCTTTAGTAGCAAACTAACATAACAGATTGGATTTATT
TTACCTGACTACAGTTTTGGGGAAACCTGTCAAATAAATAATTGTTACATGCCTTTTTTTTTTAAATTTAAGCACATTGAAACTGCTTAA
ATGGTCACATTTTTCAGCATTAGGATTAAGATACCATTTTTGTAGGCCTGGAAAACAAATAGCAAATGATTCAAAATTCATTGAATTGAC
TTTGAAATGAAACTTTTCCCCCATAATTTGTTATATGGAAGATTTGCTACCCTGATCTTTTCCCTAGCATACTTCTAAAGTTGATTGAAT
CCCTGAGTATCAATGAAGAAATCAGAGTTTAAGTGGCTAGGGAGAGCCAGGTATAAAGACTGATTAATAGAGTACTTCAGCTAATTAAAA
ATTTAAATAGTAATAATTTATGAATGTGAATAAATTGGAAGGCAGCAAAAAGCATGATTATAGAATATTAAGTTCAATTATATATAGACA
GTCCAGTTTCCTAGTGAATAGGTCAAGATTATTTGTTTTGTTTTGTGGCACTATCATAGTTCACTATAACTTCAAACTCCTGGGCTCAGG
CTATCCTCCCACCTCAGCCTCTGAAGTAGCTGGGACTACTCACATGCGCCACCATGCCCAGCTAATGGTTTTTTTCTTTAGAGATGGGGG
TCACTATACTGCCCAGGCTGGTCTTGAACTCCTAAGCTCAAGTGCTTCTCCCACATCAGCCTCCCAAAGTGCTGGGATTACAGCCATGAG
CCACTGCATCTGGCCAAGATCAAGATTATGGATATTGGTATGTTAACTTTTAAAATAAAAGTACATGGGCTGGGCGCAGTGGCTAACGCC
TGTAATCCCAGCAATTTGGGAGGCCGAGGCAGGCAGACCACCTGAGGTCAGGGGTTCGTGACCAGCCTGGCCAACATGGCGAAACCCCGT
CTCTACTAAACATACAAAAATTAGCTGGGCATGGTGGCACATGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCACTTGA
ACTCGGGAGGCGGAGGTTGCAGTGAGCCAAGATCGCGCCATTGCACTCCAGCCTGGGCAACAAGAGTGAAACTCCATCTCAGAAAATAAA
AATAAAAATAAATAAAAGTACATGAAAAAAGTATATTCCCTTAAGCAGGTAAAATACTTGCATTGTATTTTTACATCATGAATTTGCTTG
TTAAGAAATTTCTTTTCTGTAAGTGGTTAAAAGATAAACTGTATTCCATCCTCTGGGTTTTCAATTCTAAATTATTGGAGCTCAATGTAT
GACATTTTACTGTAGTGTATTCCACTGAGAGGCAAGGAAATGGGAAAGTGTCAGGTAATTATAAATGGGAAAATTTTATTTTTATATGAT
GTAAAGTTTTACAGTTTAAAATAGATCAGCATGTGATTTCTTGTAGAGATTAGCCATTTCATTTCTTTTTGCATTTTTGCCAGTTACATT
AGTTTGCCCTATGATATACTATTCTGAGATACTTCAGCCCCGCACACATCAAGTACTAATTGTATACAGATAGTACAGATTTGTACTCTG
ATTATAAGAATTTGTTACTACTAATTAAAAGCAAATTAATGTGGCTGGGCGTGGTAGCTCACACCTGTAATCCCAGCACTTTGGGTGGGC
GGCTGAGGCGGGCGGATCACGAGGTCAGGAGTTGGAGACCAGCCTGCCCAATATGGTGAAACCCTGTCTCTACTAAAATTACAAAAATTA
GCTGGGCTTGGCGGTACGTGCCTGTAATCCCAGCTACTGGGAAGGCCGAGGCAGGAGAATGGCTTGAACCCAGGAGGCGGAGGTTGCAGT
GAGCCAAGATCACACCACTGCACTCCAGCCTGGGCGACAGAGCAAGACTCCGTCTCAAAAAAAAAAAAAGCAAAATATTTTTGCTGTGAT
TGTATGTCCCCTTTTAAGGATATTTATTGCGCTTATAACCTTAATAGTTGTATTCATTACATTTCAACATGTCCAAGGTTAGCAGACATG
TAGTTCCTGAAAACCAACATTTTAAAAGTTGCCTCTGGGCTGGGCATGGTGGCTCACGCCTGTAATCCCTGCACTTTGGGAGGCCGAGGT
GGGCGGATCACGAGGTCAAGAGATGGAGACCATCCTGGCCAACATGCTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCTGGGTGT
GGTGGCACACGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCACTTGAACCTGGGAGGCGGAGGTTGCAGTGAGCCAAGA
TTGCACCGCTGCACTCCAGCCTGGCAACAGAGCAAGACTCCATCTCAAAACAAACATACAAACAAAAAAAGGTGCCTCTGGTCCTGTGTT
TTCTTTTTCCTTCTGAAAGTTCATAGAAACCTGGCATATAGAGCTTATTTTGCTGTTTTAACTGGTTGGCTCCACAAATCCTGCTACCTG
ACATCAGTACAGCTTGACCGCAGTGAAGTACTTGATGGCTTGTTCATGTTTAGTTCACCTCTTTAGAAAGAAAGCTTTGTGGCCAGGTGC
AGTGGCTCACACCTGTAATCCCAACACTTTGGGCAGCTGAGGTGAGCAGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACAT
GGCAAAACCCTGTCTCTTCTAAAAATACAAAAATTAGCCGGGTGTGGTGGCGGAGGATGCAGTGAGCCAAGATCGTGCCACTGCACTCCA
GCCTGGGCAACAGAGTGAGACTCTGTCTCAAAAAAAAAAAAAAATCGTTGTGCAGTAATAGATCATCCCAAAAAAGAATTGCCATGAACA
GCGTTATGCGTAGAAAACAGATGGAAGTGTTGGTCATTAGAGCCTTGCTTTTTAAATTTTATTCTTTCCAAAAATTGGCGGTATGCTATC
TATAATTTTATGTTTGATGTTGAAGAGGCAACACCAGAGACTAGAGAGGGAGATTACTCTGATATTTAGTGCCTAAAACTTTCATCTTGG
CCGGGCACGGTGGCTCACACCTGTAATCCCAGCACTTCGGGAGGCCGAGGCAGGCTGATTACCTGAGGTCAGGAGTTCGAGACCAGCCTG
GACAACATGGCAAAACCCGTCTCTACTAAAAATACAAAAATTAGCCAGGCATGGTGGTGGGCGCCTGTAATCCCAGCTACTCGGGAGGCT
GAGGCGAGAGAATCGTTTGAACCCGGTAGGCGGAGGTTGCAGTGAGCCGAGATCATGCCACTGCACTCCAGCCTGGGCGACAAGAGTGAA
ACTCCGTCTCAAAAAATAATAATAATTTTAAAAATAAAAGACAAAACTTTCATCTTTATTTCATGGCTTTATTTCATCTTTATTTCATTT
TTGGTTGGGAAAACAAACAAAAATCTCTTAAGTTAGTCCTTTAATAGTCTTTTTAGAACCAAAGAAGGAAAGACTGCAAAAATGTTGCAT
ACGTGACTCTTTATTGTCAGAATCTGTAGAAACTGGAGGTCTTTGTAAAGAAATAGACTAGTAGGATTGTGAGAATATATAGTGAGGGGG
GATTTAGGATAAGGCTTCCTTGCTGGGATCCTTGGACAGAAACCTTACAATTGTTTAATATTTGCAGAGTAAAAGAGCAGCTATTGCTAT
TTGAACCTACAGAAGAGACCTAAGACGAGCGTCTCTGTAATCTAAATTTATATGATAATGTTGTCCCAGACCCAAAGGCACACCTATTCT
CAGTAACTTAGAGAAGTCTTGGAAGTTGCTTCTGAATTACAGTAAAGAAATTAAATGAAGTCTTTATCCTTAAATAGGGCCAGGCATTGC
TATCAACATAGTGTCTTTGGTTTTCCCCTTTAAATAGAAAACACCAAGCAGGGCCTTTCCAGACAATGTAGTCTTTCCTGTAAAGAAAAT
GGTTTTGGTGTGGGATTTGGTAAAAACACTGGTTAGTTTGTAATGAAGAAAGAATTTTGGCATAGACAGTCCGACCCAGTTCATGGATAC
AGTTTGATCCCAGGGAGTTTAACAAAAGGAAGCTTTGGTTTTGCTAGCAACAGACTTGATCTTCTATAGTAATTAATTGCAATTAAGGTT
TTCCAGGAGCTTTCTCATTTCTTAGCCCAGGGTCCAACCCCATTCCCTCTTTAAAAAAGAAAGAATAGGCCGGGAGCAGTGGCTCATGCC
TGCAATCCCAGCACTTTGGGAGGCCAAGGCAGGTGGATCACAAGGTCAGGAGTTTGAGACCAGCGTGGCCAATATGGTGAAACCCTGTCT
CTACTAAAAATACAAAATTAGCTAGGCGTGGTGGCAGGCGCCTGAGGCTGAGGCAGGAGAATCCTGCTAGTCTGAATTACAATAAGGAAA
TTAAATGAAGGATTTATCTTTAATAGAGCCAGGCATTGCTATCAACATAACATGTTTGGTTTTCCCCTTTAAATAGAAAACACCAAGCAG
GGCCTTTCCAGACAAGGTAGTCTGGAACCCAGGAGGCGGAGGTTGCAGTGAGCCGAGATCCCACCATTGCACTCCAGCCTGGGTGGCAGA
GTGAGACTCCGTCTCAAAAAAAAAAAAAAGAAGGAATAGGAAAAGGACTTAGAGGCAGTTGATATAGAATTCTACTGGGGGTAAATGACA
CTCTCAAAATACTTGGGAAAGAAGAATCACATGCCACAAGCTATAGCTTGATTAATATTTTAGCATGTTTTCCATGTTTGTATTCTAAAG
TTTGTTTCCTTTGACATTCCATTATCTTACTTACTAGAGTGCCACCATTCTTATTTGTAATACAATCAGTGTTTTATGCCATTTGTGAAT
CACACAATTGTTCTTTTTTCCCCATCACACACACTCACACACAAACACACACACTGTTAAAAATAAAAGAGGGGAAGGATAAAACAAAAA
TAGATAGAATGATGATTATTACAATGTAACTTTAACATATATGAAGAGAAATTCTAACTCAGTTAAGTGAGAATTAAGATTGAAAGTATT
AATGTTGCAAGTATTATCTCTAGCCATGGAATTTTTTGCTGGCTATAGAATGCTAATGTGAACAGAGTATATATCAGGAATATGATGTAT
TATGGCACAGTGATAATATTATTGTTGATATTAGCCAGATGTGGTGGTTTGCACCTGTAGTCCGAACTTCTCAGGAGGATGAGGCAGGAG
GATAGTTGAGCCCAGGAGTTTAAAGCAAGCCTGGGCAATACAGCAAGACCCCAATCTTTAAAATAAATAAATAAATAAGAATTATTCTTG
AAAGTAATATTCTAACCTTCTGCCAACCAACAGAGATCCTCATATTCTTAAAGAAAATTAATATAGCTTATGGTTTTGATAAATTGGACT
CTGATTTAAACTTTAAAATGTTATGACTTTTATTCTGATACATGGCTTCTAAAATATGTAAAAAATTATATTGAATGAATTAATACTTAA
CCTGTTCATTTCTCTTAATTTATGTATTTATTCTGACTTTATTATACAGCTTATGTCTCACATCTGCCTTCTTGATATGTGCAAAATATT
GTGTAAAAATAGTTTAAAACTCATCCCAGTTCCTAGTCAAGCGTGGGCTATAAGAGAGAAGGCTTAAGGTGTTCTTTAATGGAGGAACTT
TTGAAAGATCACAAATGGAAAAAGCCTATTGAGAATTTATTGCCTTTGAGAGTAGAAAGGGCTCTAGAATATGAGCCAGAGACTTGGAAT
TTAGTAATAGGTCTCCCACTGATTTGCTCCGTGTCCTTAGGCAATTCGTTTAATCTCTGTGTGCCTAGTTTCCCCTTGTAAATAAGAGTG
GTAATACCTGTCCTCACCTACCTCACTAAATTGTTGGAGTTCTTTTGTTCTGAGTCAGGGTCTCACTCTGTTGCCCAGGCTGAACTACAG
TAGTGTGATCATAGCTCACTACAGCCTCCAACTCCTGGGCCCAAACTATCCTCCTGCTTCAGCCTCCCAAGTAGCTGGGACTAGAGGTAC
ATGCCACCACACCCAGCTAATTATTTTCTTTTATTGCAGAGATGGGGTCTCACATGTTGCCAAGGCTGATCTCTAACTCCTGAGCTCAAG
CAGTCCTCCTGCCTCAGCCACCCAAAGTGCTGGGATTATAGGCATGATCACTAAATTGTTGTAAGAATAAGATAATGTTTGCGGAAGCAT
TTGAGTTCTCCAAAGGAAAAGCTATTCAGACGTTCAAGATAATAGAAGAGTGTTGTGTGAAGGATTCCTTTCCAGTTTGCCTCTGTGAAA
ATGTCTTTGTTGTAGATCATTTTATGAAATAGGAATAAGAGAAACATAGGCCTTATCATGGTGTAGTGTTCACTTACAAACATATCCTGT
TGTTTCTTCCCTGCAAGATATCCAGCACACAGGCTGAATTTTTCTTTATAATAATCCTTGGCAAAAGCATAACTTTTCAAAAACCAAATG
ATTTTAGTGGTGCTATGGCAGCTGCAGTTTTGAGTTAGATTAATGTGGTGAAAACCATCAAATACTTAGAAATTGACTGGGTGCGGTGGC
TCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTAGGTGGATCACTTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGCAAA
ACCCCGTCTCTACTAAAGATACAAAAATTAGCTGGGCACGATGGAGGGTGCCTGTAATCCCAGCTACTCGGGAGGCTAAGGTGGGAGAAT
TGCTTGGACCCAGGTGGCAGAGGTTGCAGTGAGCCAAGATTGTGCCACTGCACTCCAGCCTGGGCAACAAAGCGAAGCTCTGTCTCAATA
AAAAAAAAAATAATAATAATAAAATACAAATACTTAGAAATTAACTTCGCCTTTGCCTTCAGGCACTTTTGCTACATGTTAGCATCAGAG
GCTATTGTACAACTAGATGGTTATTCCCTGTTTCTTGGCCGATTTTTGGTACCTTTCTTTGAAGAAGAGGGTTAGATTTTAAGAAAGAAA
GTGTGCTTATTTCACTCATGTCTTTGCAGAATTTAACTTTGCTTTACTTTAAAAATTCCAATCATCATGTACCTATAAAGGTTAAAATAT
AGTGAAAGTTTCTGCTTCATGTGAATTCAATTCTGAGCACCTGCAGGTCATATCAGGTGTCTGATGCAGTTACCTTTATAGATCGTGGCA
GGTCCTTACATTTCAACAGGCTTATGCATTTCCATGGGGGGAAGAGATTCTGTTTCTAGGAAATTACAAAGGGCACACCACTGCAGGGAG
TGTAAACAATTCTTTGTTGCAACAGACAAGATTTTTTTTAAAAAAAGAAAAAAGGATGCATTTTAGGTACACAGGGTATGGACGCATTCA
ACATTTACTTTTATCTCCACAGATGCCAACCTCCCCTTGTTGCAGGCAGTTGGGCTTTTCCAACTCATTGCTAACAAAGCTGGCATCTGC
ATTAATTTCAATGAGAATTTCAAGTACTGAAGATGAAAAGTTGGGGAGATTCATGTTTGAAAAATGAAAAATGAACAAAAAATCCACCTT
GTGCAGTGAGATAGCTAACGCTGATATATCAGGAATAATTTTAAACTATTTTTGCTGTAATGTGTAGCTTTAATGTCTCTTTTCAGTTAT
GGACCCATAAAAGTATTCCTATATCTTGTGAATAAAGATCATTCTTGTGGACTAGTACGTGGATGCATTCATAGGCTTTGGGAAGCAGTG
GTGTGCGTATGTGTGTCTATATCAATATTTTATGTTTATAACTCTGCGTATTAAGTTTATATAGAAAAAAATAATGTCTTTCTTTAGTGT
TTGGGGGACTCAATGGTAATATGACCATTGCAGTGTAATCTGACTGCTCACTCTAGAGAACACTTCTGTTATACACAATGCACATACAAA
CATACACCCCTAAAGCGTAGCTAACTGCTCCCACTAGATAATTGCTGCTAAAAACAAAACAAAACAAAACAATACAAAACAAAAAAAACC
CTAAGTAATGGAGGAAGAAATAGCATTCTTTTAAAAGGGGCTTTTCTGAAGAGTAAAATGTAAATACAGGACATGTGGGGAGGGTGGGGC
CGCCTGCAAAATGTCCTGAAGATGGACAAATAGCCTTTTAAATTCTACTTTTTAACCATCTTTACCGTGTGTGCCTATTTGTATTGCAGA
TGTGAACTACTATTTTTGGAGGTTGATATCAGTATGTTTTGAAACTGAATTATTACATAAAATCAGAGTAACCTCTTTCTCCATCCTCCT
TTTCCACACTATTCTTGCCAAATATTTCTACTGAAACCCAGTTTCAGCAAGGCAAAATGATGGGACTCTCAAACCTCCCTCCTCATCTTC
CCTTCCCCTCTGTCTTATGCCTGGCCTGGCCTTTTTTGTTGTTGTTGGCTTTTCATAAGTAAGAAAAATTTATTGTAGTATTTCAAGACT
GCAGAATTTCAAGTGTATATCTATAAATCTTTTTTTAAAATCTTCGGCTACACAGTAACATCAATTAAAACAGAAGAGTGAGTCTAAGTC
TGTAATATGCTGTAGGACCAGATAAGATTTTGAATGAGACTAAACTTGACTGCCATATTTTAAGAGGAAATTGAAACTTTATGGTGGAGA
ATGGATGAGAGCAAGTCTATGATATATATGTAGTCATTGTATAATTAGAAACACCAAATGCTGAATCCTATCACTGTGTTCTTGGGGGCC
AGGCCTTGGATTTGGTTGTCATTTAAACTCCTTGAAGATTATATGTAATTATAATGAGCAGAAGGCAAATAAAGTTTTTGAACAAAAGTC
CTTGTTTTCAGTATTTAAAATTTGGTAATATATTTTCTTTTTCAGTTAAACTATCTTCCCCACAAAAAATATTATACTTCAGTTAAACTA
TCTTCCCCACAGAAATTATTATACTACGAACAAGTTATGAGTGAGACTGAGAAGCTTGAAGAAGCTGGTTTTTAAGCAGCTCATATAATA
TTTTGTGTTAAAGAAAGTGTCATTGTTTCCTGTTGGGAGGCAAATAACAACAACAACAAAAGAAATTGTCATGATTCTTTCTGAGCCAAA
CTGTCACGAAATGTTCTGTGACAGAACCACTACTCTTTTTTCTGCCATTCTGCCTACTGGAGAGTTCTATGTTGTATTTGTTTTTAATCC
TTGATTTTAAAAATATTAATGGTTTTAGTGTTGCTTAGCTTCAGTTTGAAGTATAACTTTCACTAATAACTGCAATAAAAAGAAAAGCTT

>In-frame_ARHGEF2_ENST00000313695_chr1_155927504_-_AGO3_ENST00000397828_chr1_36432556_+_2611nt
GGGATCCCGGGAGGGAGCGGAGCGGACCTGGGCTTGGTCGCCTCCAAGCCGGCGGGACCGAGTGCTTTAGGCCGCTTGAAAGAAAGTTGC
TCCGACCCGGGAAAAGGAGAAGATGAAGGAAGCCAAGGATGCCCGCTATACCAATGGGCACCTCTTCACCACCATTTCAGTTTCAGGCAT
GACCATGTGCTATGCCTGTAACAAGAGCATCACAGCCAAGGAAGCCCTCATCTGCCCAACCTGCAATGTGACTATCCACAACCGCTGTAA
AGACACCCTCGCCAACTGTACCAAGGTCAAGCAGAAGCAACAGAAAGCGGCCCTGCTGAAGAACAACACCGCCTTGCAGTCCGTTTCTCT
TCGAAGTAAGACAACCATCCGGGAGCGGCCAAGCTCGGCCATCTACCCCTCCGACAGCTTCCGGCAGTCCCTCCTGGGCTCCCGCCGTGG
CCGCTCCTCCTTGTCTTTAGCCAAGAGTGTTTCTACCACCAACATTGCTGGACATTTCAATGATGAGTCTCCCCTGGGGCTGCGCCGGAT
CCTCTCACAGTCCACAGACTCCCTCAACATGCGGAACCGAACCCTATCCGTGGAATCCCTCATTGACGAAGAGGTAATCTACAGTGAGCT
GATGAGTGACTTTGAGATGGATGAGAAGGACTTTGCAGCTGACTCTTGGAGTCTTGCTGTGGACAGCAGCTTCCTGCAGCAGCATAAAAA
GGAGGTGATGAAGCAGCAAGATGTCATCTATGAGCTAATCCAGACAGAGCTGCACCATGTGAGGACACTGAAGATCATGACCCGCCTCTT
CCGCACGGGGATGCTGGAAGAGCTACACTTGGAGCCAGGAGTGGTCCAGGGCCTGTTCCCCTGCGTGGACGAGCTCAGTGACATCCATAC
ACGCTTCCTCAGCCAGCTATTAGAACGCCGACGCCAGGCCCTGTGCCCTGGCAGCACCCGGAACTTTGTCATCCATCGCTTGGGTGATCT
GCTCATCAGCCAGTTCTCAGGTCCTAGTGCGGAGCAGATGTGTAAGACCTACTCGGAGTTCTGCAGCCGCCACAGCAAGGCCTTAAAGCT
CTATAAGGAGCTGTACGCCCGAGACAAACGCTTCCAGCAATTCATCCGGAAAGTGACCCGCCCCGCCGTGCTCAAGCGGCACGGGGTACA
GGAGTGCATCCTGCTGGTGACTCAGCGCATCACCAAGTACCCGTTACTCATCAGCCGCATCCTGCAGCATTCCCACGGGATCGAGGAGGA
GCGCCAGGACCTGACCACAGCACTGGGGCTAGTGAAGGAGCTGCTGTCCAATGTGGACGAGGGTATTTATCAGCTGGAGAAAGGGGCCCG
TCTGCAGGAGATCTACAACCGCATGGACCCTCGGGCCCAAACCCCAGTGCCTGGCAAGGGCCCCTTTGGCCGAGAGGAACTTCTGAGGCG
CAAACTCATCCACGATGGCTGCCTGCTCTGGAAGACAGCGACGGGGCGCTTCAAAGATGTGCTAGTGCTGCTGATGACAGATGTACTGGT
GTTTCTCCAGGAAAAGGACCAGAAGTACATCTTTCCTACCCTGGACAAGCCTTCAGTGGTATCGCTGCAGAATCTAATCGTACGAGACAT
TGCCAACCAGGAGAAAGGGATGTTTCTGATCAGCGCAGCCCCACCTGAGATGTACGAGGTGCACACAGCATCCCGGGATGACCGGAGCAC
CTGGATCCGGGTCATTCAGCAGAGCGTGCGCACGGAGGTGGTTGACTCAATGGTTCAGCATTTTAAAGTAACTATATTTGGAGACCGTAG
ACCAGTTTATGATGGAAAAAGAAGTCTTTACACCGCCAATCCACTTCCTGTGGCAACTACAGGGGTAGATTTAGACGTTACTTTACCTGG
GGAAGGTGGAAAAGATCGACCTTTCAAGGTGTCAATCAAATTTGTCTCTCGGGTGAGTTGGCACCTACTGCATGAAGTACTGACAGGACG
GACCTTGCCTGAGCCACTGGAATTAGACAAGCCAATCAGCACTAACCCTGTCCATGCCGTTGATGTGGTGCTACGACATCTGCCCTCCAT
GAAATACACACCTGTGGGGCGTTCATTTTTCTCCGCTCCAGAAGGATATGACCACCCTCTGGGAGGGGGCAGGGAAGTGTGGTTTGGATT
CCATCAGTCTGTTCGGCCTGCCATGTGGAAAATGATGCTTAATATCGATGAAAGAGACCTCTGGCAGCAGTGTGGAGAATAGATAGAGGA
GAAAAAACTAATCTGAGAAGCCAGTTAGGAGGCTTTTCAATCACTAGTTCAGGTTTCAGTCTACATGTTACTTCCTTGAGAAGCAGTGTT
TGACACCCTTCTCCCCCAATCCAGCCATCCCCCAAGTCTGAGTTAGGTATTTCTCTTCTGTATTCCCATAGCACAGTGTAATTCCCCTAT
AATAGCATGTATCACCTTGAATTATGGGTGTTTATTGTTCTGTCTCTCCTGTTAGAACGAAAGCTCCATGAAGGGATTGTCATTTTATTC
ACCAGTGTACCCTCTATGCCCAGCACAACTTTTGGTCATATTAAACAAAGAATGAATAAATAAATCCAAGAGCATAGGAGGAGGAGCATC

>In-frame_ARHGEF2_ENST00000361247_chr1_155927504_-_AGO3_ENST00000324350_chr1_36432556_+_3071nt
GAGACCAACGCGTGCGGGCCGAACCCCTCCCCCCGCCTTCCCCCAACAATACAGGACGCCGGGGTCCGCGCCGCGTCCTCCCTGGTCCCC
CCGTCCGATTATGTCTCGGATCGAATCCCTCACGCGGGCGCGGATCGACCGGAGCAGAGAGCTGGCGAGCAAGACCCGGGAAAAGGAGAA
GATGAAGGAAGCCAAGGATGCCCGCTATACCAATGGGCACCTCTTCACCACCATTTCAGTTTCAGGCATGACCATGTGCTATGCCTGTAA
CAAGAGCATCACAGCCAAGGAAGCCCTCATCTGCCCAACCTGCAATGTGACTATCCACAACCGCTGTAAAGACACCCTCGCCAACTGTAC
CAAGGTCAAGCAGAAGCAACAGAAAGCGGCCCTGCTGAAGAACAACACCGCCTTGCAGTCCGTTTCTCTTCGAAGTAAGACAACCATCCG
GGAGCGGCCAAGCTCGGCCATCTACCCCTCCGACAGCTTCCGGCAGTCCCTCCTGGGCTCCCGCCGTGGCCGCTCCTCCTTGTCTTTAGC
CAAGAGTGTTTCTACCACCAACATTGCTGGACATTTCAATGATGAGTCTCCCCTGGGGCTGCGCCGGATCCTCTCACAGTCCACAGACTC
CCTCAACATGCGGAACCGAACCCTATCCGTGGAATCCCTCATTGACGAAGCAGAGGTAATCTACAGTGAGCTGATGAGTGACTTTGAGAT
GGATGAGAAGGACTTTGCAGCTGACTCTTGGAGTCTTGCTGTGGACAGCAGCTTCCTGCAGCAGCATAAAAAGGAGGTGATGAAGCAGCA
AGATGTCATCTATGAGCTAATCCAGACAGAGCTGCACCATGTGAGGACACTGAAGATCATGACCCGCCTCTTCCGCACGGGGATGCTGGA
AGAGCTACACTTGGAGCCAGGAGTGGTCCAGGGCCTGTTCCCCTGCGTGGACGAGCTCAGTGACATCCATACACGCTTCCTCAGCCAGCT
ATTAGAACGCCGACGCCAGGCCCTGTGCCCTGGCAGCACCCGGAACTTTGTCATCCATCGCTTGGGTGATCTGCTCATCAGCCAGTTCTC
AGGTCCTAGTGCGGAGCAGATGTGTAAGACCTACTCGGAGTTCTGCAGCCGCCACAGCAAGGCCTTAAAGCTCTATAAGGAGCTGTACGC
CCGAGACAAACGCTTCCAGCAATTCATCCGGAAAGTGACCCGCCCCGCCGTGCTCAAGCGGCACGGGGTACAGGAGTGCATCCTGCTGGT
GACTCAGCGCATCACCAAGTACCCGTTACTCATCAGCCGCATCCTGCAGCATTCCCACGGGATCGAGGAGGAGCGCCAGGACCTGACCAC
AGCACTGGGGCTAGTGAAGGAGCTGCTGTCCAATGTGGACGAGGGTATTTATCAGCTGGAGAAAGGGGCCCGTCTGCAGGAGATCTACAA
CCGCATGGACCCTCGGGCCCAAACCCCAGTGCCTGGCAAGGGCCCCTTTGGCCGAGAGGAACTTCTGAGGCGCAAACTCATCCACGATGG
CTGCCTGCTCTGGAAGACAGCGACGGGGCGCTTCAAAGATGTGCTAGTGCTGCTGATGACAGATGTACTGGTGTTTCTCCAGGAAAAGGA
CCAGAAGTACATCTTTCCTACCCTGGACAAGCCTTCAGTGGTATCGCTGCAGAATCTAATCGTACGAGACATTGCCAACCAGGAGAAAGG
GATGTTTCTGATCAGCGCAGCCCCACCTGAGATGTACGAGGTGCACACAGCATCCCGGGATGACCGGAGCACCTGGATCCGGGTCATTCA
GCAGAGCGTGCGCACGGAGGTGGTTGACTCAATGGTTCAGCATTTTAAAGTAACTATATTTGGAGACCGTAGACCAGTTTATGATGGAAA
AAGAAGTCTTTACACCGCCAATCCACTTCCTGTGGCAACTACAGGGGTAGATTTAGACGTTACTTTACCTGGGGAAGGTGGAAAAGATCG
ACCTTTCAAGGTGTCAATCAAATTTGTCTCTCGGGTGAGTTGGCACCTACTGCATGAAGTACTGACAGGACGGACCTTGCCTGAGCCACT
GGAATTAGACAAGCCAATCAGCACTAACCCTGTCCATGCCGTTGATGTGGTGCTACGACATCTGCCCTCCATGAAATACACACCTGTGGG
GCGTTCATTTTTCTCCGCTCCAGAAGGATATGACCACCCTCTGGGAGGGGGCAGGGAAGTGTGGTTTGGATTCCATCAGTCTGTTCGGCC
TGCCATGTGGAAAATGATGCTTAATATCGATGAAAGAGACCTCTGGCAGCAGTGTGGAGAATAGATAGAGGAGAAAAAACTAATCTGAGA
AGCCAGTTAGGAGGCTTTTCAATCACTAGTTCAGGTAAGAGATGGTGATGGTCTAATGTGGGATGGAGAGGAAGGATTAAGCTGAAAAAA
TAGGTTTAAGAACCATGTCCAGAAAAAAAAAACTTTGGGTGTAGTACTGGTACATGGAACGGATTGGAAAAAAATAGACCAGAGCTTTAC
TAGATTTTTGAAAGAATTGTTTTTGCAAATAAACTACAAGCCTGGCATATCAGTCAAGGTTCAGAACCTAGAGAAGCAGAACCAGTACGA
AGTATAGAGAGAGAGTTTATGCAATTGTAGGGGCTAGCTAGGCAAGTCTGAAATTTTGGGGGCAGGCTGTCAGGAAGGGCAGGGAAATTC
AGGCATGGGCTGAAGCAGTTATCTATAAGTGGAATTTCTTGCTCTCAGGGAAGCTTCAGCCCTACTTTTAAGACCTTTCACCTAATTGAA
TCAGGCCCATCCACATTATTCAGGATAATCTCCATTACTTAAAGTCAACAGATTATGGATTTTAATTACATCTACAAAATACCTTCATAG
CAACACCTAGATTAGTGTTTGATTAAACAAATGGCAGCTGGTAGCCTAGCAAGTTAACACATTAAAAACAACACCTGCCATGATGGCTTA
CACTTGTAATCCCAGCACTTTGGGAGGCCAAAGTGGGAGGATCACTTGAGATTAGGAGTTTGCGATCAGGCTGAACAACATAGTGAGACC

>In-frame_ARHGEF2_ENST00000361247_chr1_155927504_-_AGO3_ENST00000373191_chr1_36432556_+_20962nt
GAGACCAACGCGTGCGGGCCGAACCCCTCCCCCCGCCTTCCCCCAACAATACAGGACGCCGGGGTCCGCGCCGCGTCCTCCCTGGTCCCC
CCGTCCGATTATGTCTCGGATCGAATCCCTCACGCGGGCGCGGATCGACCGGAGCAGAGAGCTGGCGAGCAAGACCCGGGAAAAGGAGAA
GATGAAGGAAGCCAAGGATGCCCGCTATACCAATGGGCACCTCTTCACCACCATTTCAGTTTCAGGCATGACCATGTGCTATGCCTGTAA
CAAGAGCATCACAGCCAAGGAAGCCCTCATCTGCCCAACCTGCAATGTGACTATCCACAACCGCTGTAAAGACACCCTCGCCAACTGTAC
CAAGGTCAAGCAGAAGCAACAGAAAGCGGCCCTGCTGAAGAACAACACCGCCTTGCAGTCCGTTTCTCTTCGAAGTAAGACAACCATCCG
GGAGCGGCCAAGCTCGGCCATCTACCCCTCCGACAGCTTCCGGCAGTCCCTCCTGGGCTCCCGCCGTGGCCGCTCCTCCTTGTCTTTAGC
CAAGAGTGTTTCTACCACCAACATTGCTGGACATTTCAATGATGAGTCTCCCCTGGGGCTGCGCCGGATCCTCTCACAGTCCACAGACTC
CCTCAACATGCGGAACCGAACCCTATCCGTGGAATCCCTCATTGACGAAGCAGAGGTAATCTACAGTGAGCTGATGAGTGACTTTGAGAT
GGATGAGAAGGACTTTGCAGCTGACTCTTGGAGTCTTGCTGTGGACAGCAGCTTCCTGCAGCAGCATAAAAAGGAGGTGATGAAGCAGCA
AGATGTCATCTATGAGCTAATCCAGACAGAGCTGCACCATGTGAGGACACTGAAGATCATGACCCGCCTCTTCCGCACGGGGATGCTGGA
AGAGCTACACTTGGAGCCAGGAGTGGTCCAGGGCCTGTTCCCCTGCGTGGACGAGCTCAGTGACATCCATACACGCTTCCTCAGCCAGCT
ATTAGAACGCCGACGCCAGGCCCTGTGCCCTGGCAGCACCCGGAACTTTGTCATCCATCGCTTGGGTGATCTGCTCATCAGCCAGTTCTC
AGGTCCTAGTGCGGAGCAGATGTGTAAGACCTACTCGGAGTTCTGCAGCCGCCACAGCAAGGCCTTAAAGCTCTATAAGGAGCTGTACGC
CCGAGACAAACGCTTCCAGCAATTCATCCGGAAAGTGACCCGCCCCGCCGTGCTCAAGCGGCACGGGGTACAGGAGTGCATCCTGCTGGT
GACTCAGCGCATCACCAAGTACCCGTTACTCATCAGCCGCATCCTGCAGCATTCCCACGGGATCGAGGAGGAGCGCCAGGACCTGACCAC
AGCACTGGGGCTAGTGAAGGAGCTGCTGTCCAATGTGGACGAGGGTATTTATCAGCTGGAGAAAGGGGCCCGTCTGCAGGAGATCTACAA
CCGCATGGACCCTCGGGCCCAAACCCCAGTGCCTGGCAAGGGCCCCTTTGGCCGAGAGGAACTTCTGAGGCGCAAACTCATCCACGATGG
CTGCCTGCTCTGGAAGACAGCGACGGGGCGCTTCAAAGATGTGCTAGTGCTGCTGATGACAGATGTACTGGTGTTTCTCCAGGAAAAGGA
CCAGAAGTACATCTTTCCTACCCTGGACAAGCCTTCAGTGGTATCGCTGCAGAATCTAATCGTACGAGACATTGCCAACCAGGAGAAAGG
GATGTTTCTGATCAGCGCAGCCCCACCTGAGATGTACGAGGTGCACACAGCATCCCGGGATGACCGGAGCACCTGGATCCGGGTCATTCA
GCAGAGCGTGCGCACGGAGGTGGTTGACTCAATGGTTCAGCATTTTAAAGTAACTATATTTGGAGACCGTAGACCAGTTTATGATGGAAA
AAGAAGTCTTTACACCGCCAATCCACTTCCTGTGGCAACTACAGGGGTAGATTTAGACGTTACTTTACCTGGGGAAGGTGGAAAAGATCG
ACCTTTCAAGGTGTCAATCAAATTTGTCTCTCGGGTGAGTTGGCACCTACTGCATGAAGTACTGACAGGACGGACCTTGCCTGAGCCACT
GGAATTAGACAAGCCAATCAGCACTAACCCTGTCCATGCCGTTGATGTGGTGCTACGACATCTGCCCTCCATGAAATACACACCTGTGGG
GCGTTCATTTTTCTCCGCTCCAGAAGGATATGACCACCCTCTGGGAGGGGGCAGGGAAGTGTGGTTTGGATTCCATCAGTCTGTTCGGCC
TGCCATGTGGAAAATGATGCTTAATATCGATGTTTCTGCCACTGCCTTCTACAAAGCACAACCTGTAATTCAGTTCATGTGTGAAGTTCT
TGATATTCATAATATTGATGAGCAACCAAGACCTCTGACTGATTCTCATCGGGTAAAATTCACCAAAGAGATAAAAGGTTTGAAGGTTGA
AGTGACTCATTGTGGAACAATGAGACGGAAATACCGTGTTTGTAATGTAACAAGGAGGCCTGCCAGTCATCAAACCTTTCCTTTACAGTT
AGAAAACGGCCAAACTGTGGAGAGAACAGTAGCGCAGTATTTCAGAGAAAAGTATACTCTTCAGCTGAAGTACCCGCACCTTCCCTGTCT
GCAAGTCGGGCAGGAACAGAAACACACCTACCTGCCACTAGAAGTCTGTAATATTGTGGCAGGGCAACGATGTATCAAGAAGCTAACAGA
CAATCAGACTTCCACTATGATCAAGGCAACAGCAAGATCTGCACCAGATAGACAAGAGGAAATTAGCAGATTGGTAAGAAGTGCAAATTA
TGAAACAGATCCATTTGTTCAGGAGTTTCAATTTAAAGTTCGGGATGAAATGGCTCATGTAACTGGACGCGTACTTCCAGCACCTATGCT
CCAGTATGGAGGACGGAATCGGACAGTAGCAACACCGAGCCATGGAGTATGGGACATGCGAGGGAAACAATTCCACACAGGAGTTGAAAT
CAAAATGTGGGCTATCGCTTGTTTTGCCACACAGAGGCAGTGCAGAGAAGAAATATTGAAGGGTTTCACAGACCAGCTGCGTAAGATTTC
TAAGGATGCAGGGATGCCCATCCAGGGCCAGCCATGCTTCTGCAAATATGCACAGGGGGCAGACAGCGTAGAGCCCATGTTCCGGCATCT
CAAGAACACATATTCTGGCCTACAGCTTATTATCGTCATCCTGCCGGGGAAGACACCAGTGTATGCGGAAGTGAAACGTGTAGGAGACAC
ACTTTTGGGTATGGCTACACAATGTGTTCAAGTCAAGAATGTAATAAAAACATCTCCTCAAACTCTGTCAAACTTGTGCCTAAAGATAAA
TGTTAAACTCGGAGGGATCAATAATATTCTTGTACCTCATCAAAGACCTTCTGTGTTCCAGCAACCAGTGATCTTTTTGGGAGCCGATGT
CACTCATCCACCTGCTGGTGATGGAAAGAAGCCTTCTATTGCTGCTGTTGTAGGTAGTATGGATGCACACCCAAGCAGATACTGTGCCAC
AGTAAGAGTTCAGAGACCCCGACAGGAGATCATCCAGGACTTGGCCTCCATGGTCCGGGAACTTCTTATTCAATTTTATAAGTCAACTCG
GTTCAAGCCTACTCGTATCATCTTTTATCGGGATGGTGTTTCAGAGGGGCAGTTTAGGCAGGTATTATATTATGAACTACTAGCAATTCG
AGAAGCCTGCATCAGTTTGGAGAAAGACTATCAACCTGGAATAACCTACATTGTAGTTCAGAAGAGACATCACACTCGATTATTTTGTGC
TGATAGGACAGAAAGGGTTGGAAGAAGTGGCAATATCCCAGCTGGAACAACAGTTGATACAGACATTACACACCCATATGAGTTCGATTT
TTACCTCTGTAGCCATGCTGGAATACAGGGTACCAGTCGTCCTTCACACTATCATGTTTTATGGGATGATAACTGCTTTACTGCAGATGA
ACTTCAGCTGCTAACTTACCAGCTCTGCCACACTTACGTACGCTGTACACGATCTGTTTCTATACCTGCACCAGCGTATTATGCTCACCT
GGTAGCATTTAGAGCCAGATATCATCTTGTGGACAAAGAACATGACAGTGCTGAAGGAAGTCACGTTTCAGGACAAAGCAATGGGCGAGA
TCCACAAGCTCTTGCCAAGGCTGTACAGATTCACCAAGATACCTTACGCACAATGTACTTCGCTTAAATAGTCCAAGTATATTCTCTGAG
AGGAAGTACTGAAAGATGAATTGACATACAACGTATGTTTCCAGTGAAGTCAATTGAGTAAGGACACCTCCAGCCATACAGAAACCAACA
CTGTGTGGGGGCCAAGGTCTGATCCTTATGTTAATACAAGGAAGATTGTTTACTTCATCAAGGAACACAGCATCATTATGCAATATGAAA
CCAGCCAACTGCTTTTTGTGCGGTCTCCTATAGGAAGTATCGCAATTGTTTTGTTTTCATTTCTTGTAGTCTAACCCTTTTAATGCCTTT
ACCTCAAGTTGCTTGGCAGCACAACTATCTTTGCAAAAAAAAGTAAAGAAAAAGTAAATGATGGTTTAAAAAATACACACCTTCATGAAT
AATCAAAGTGATTTTTCAGAATTATGTGTGCAAAAAATTAATGTGCATTCATATATTCTTGTAAAAGGTGTCTGTGTATTTTTAAAATAT
ATACATCCATACTTCATATGCATATATATCTAGATCTGGATTGATAATAGATATATATGTGTCTGTTATATATTTTAGAGTTCATTCCAT
TGGGGAATTTTCTTTCCCTTTTATTCTACCCCCACTACCGCCTTTATTTCTCTATTTCCCTTGCCTTCATCACCTACATTTTTTTCCCAG
TCCTACCAGTGACATTCAAATGTTGATGTATCTGGTTCGTTTGAATATAAAATATGGCAAACTAGAATTCTACTTTTATTTTGCATACCC
TACTCCTGACTCCTATCTCATACACAATTCTGAGTTCTCAACTCTTGATATTGCTGTCTTAAGAAACAAAATTTTATATATATATGTATA
CATACATACACAGACACAGACACACACATATATATACATAAAATAACTTTCTGTGAGAGTGCGTCTCTCCCCTCCCACTCAGAACATACA
TTTACCATTTGCGCAATTTGTATATAAGCAGTAGCAACCTGAACTATTCTTTTTCTTTTTTCTTTTTCTTTTCTTTCTTTTTTTTTTTTA
ATGAGACAGAGCCTCGCTCTGTCACCAGGCTGGAGTGCAGTGGCGAGATCTCGGCTCACTGCAACTTCCGCCTCTCGGGTTCAAGCAATT
CTCCTGCCTCAGCCTCCCGAGTAGCTGGGTTTACAGGCATGTGCCACCACACCCAGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTC
ACCGTGTTGGCCAGGATGGTCTCGATCTCTTGACCTTGTGATCCACCCGCCTCGACCTCCCAAAGTGCTGGGATTACAGGCATGAGCCAC
CGCACCCGGCCTACTATTCTTTTTCTTTAGTGAGTTTGTTAAAGCTGCTATAAATATAAAACCTGTCAGAAGTTGTAACTTTCTCTCTGG
TAAGTGATGTGTATTCTGAAGCCTTCTGTTTCTATGGGTTATACATGGAAATTCTTTAAAGGTTTTATAAAGGGTAAATATTTTAAAAGA
TTAGAGCTCTGTAGGGTTGAGACCTCTGAAATTGAGTAGAGAGAAGAGTTTGTTGAGGGATTTTTTTGTTTTGTTTTTTGATAGTTTACT
TGCTGCCTCTCATACCTTAATGTGATTTTCATATATTTTTTATATATATATATGTATGTGTGTGTATATAAACACATATGTATGTGTTTG
GAAGTATAGCTTCCTTTTCTTTTATATTTATTAGAATAGTGCTTTAATAATTATAGAATTGTATTGGCAGCATCTTTTATAGAAATATAA
TCATGTTTATTTTAAGAACTGACAACTTGTTTTTGCTATCTTTTAGTGCAATAAGCAGTTTTAAAGGAAAGTTGTGTCTGCATCTTTACC
ATGGATAGTAGGAGGAACAGGCACCTCCATAGTTTAAAAGGGCAAAGAATACAGCCTTAATTTCAGAAGGAAAGTTTTGTAATTTTCAGT
TTTAAAGCATATCTTTTAAAATTCATCATGATAAAAGGCTGGACGCGGTGGCTCATGCCTGTAATCCTAGCACTTTGGGAGGCTGAGACA
GGTATATCACCGGAGCTCAGGAGTTTGAGACCAGCCTGGCCAACGTGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCTGGGCG
TGGTAGTGGGCACCTCTAATCCCAGCTACTCGGGAGGCTGAGGCAGGATTGCTTGAACCTAGGAGGCGGAAGTTACAGTGAGCCAAGACT
GCACCATTGCACTCCAGCCTGGGCAACAAAACCAAAACTCCGTCTCAAAAGAAAAAAAAATCATAATGAAAATGAAGTGAAATTGCCTAA
ATGAGTCCAACTTGAATATTAGAAATAAAGTTGAACTTTTATATAATTGTGAATAGCTTAACATATTTAAATTATTTGCAAATAGATTGT
GTTTATTGAAGAATCATATTGGCTAGATGCCCATTTTCATTTACTAAAATGAATCAGGAAAATGCAAGATGATATTTTAAAACTTTTGCT
AATGTATCACCAGTATAACTTTCCTTTTAAAATTAAGGTGATAGTAACAAAGGAAGTTAGGACTTTGATCATTTTAAATCAGTTAAATCA
CTGAAACGTGGGAAATTGTTTTACAAAACTTTTATTGATTACACTTTAAGGTATTAAAAAGTACTATAAAGCTATCAAAACTGAGTTTAT
CAGTAACATTGGATTCAGGGGAGCTTTGCACTTTGTAACTCATGAAAATTGCATTTTGATTTTTTTTTTTTTTGCACTGGTTCAGAGTAT
AGATACTACAGATTGTTTCCAGTGGGCATTGTTGTTAGCCTTTCAGAATTCCATCTGCACGTGAAACCTAATGGATTTAGATCTTTAGTT
TCTCTCTTACCTGTAATCCACTATTATTGCCAATTCACTGTATTTTGAGCCTAAAATCTGAGCCCATGTCCTCTGACAGGCATGAAATCT
TTTGTCCCTCTGCCAGAAAACTAAGAAAGTACTGTATTTTGTATGTTTATTATTTTGAAGTGTCTGAAATGCAATTTACAACACTGTTGC
AAAGAACTTTACAAAAGGTAATATTTGTATCGTATATACATTTTTTCTCCCAGCCTTCTCCCATCTCCTCCAGAAAAATTTCCTATAAAG
ATGGATTTTTTTACACTGAAATTTTACTGAATATAGTCAGGATCATGGGCAAGAGAAGAAAATAGTATACCCAAGATGATAAAAATTTAA
TTCGTCTATGCTTGATCAGTGTGAGTAAAACATCTTCCTTTATCATGGGAGCTGCACAGATTCATGTGGGAAACTTTAGGGAATGACTGT
AGATACCCTTTCTCTATGTACTCTCTCACCTAATTTTCAGTCACTCATATATGCTAGAGTGGAGCCCTTAATTTAAATCTATTTGGAAGG
ACTTTTTTAAGAGGAAAAATATTTTTTCTAAATTATAAAGCTTTACCTTTTGAGTGATTTCTTTTTTAGAGTGCTCTTACACTAGTCAGC
ATTGCTAGTTTAAAGTTGATTAACTTGAAAGAGTATGTATACTATATTTCTATTTTGCTAACAAATTGGTATATTAATTACCATTGGTTC
TTAATTACAAGAAAACTTGTGCTTAGAATTTTAAGATAAAAGGCTAAGTGACAAATGCTTCTTGAAATTTGTCCTATTTATTGTTGCATT
TCTGGTGTAGAATTTCTAATCTTTTTTATTTTAAAAAAGTTTTTTTTTTTAAGTTAAACATGAAATTCACAGTGACCCTTCTGCTCCTGC
CCTTGCTCACTAACTATATCATGAATGCTAGATTTTGGTCTTCTTTTTTCTGTGATGTATCTTACGAGACTGACTGTAAAATATCAGTCT
GGCAACTAGATAATTGATTTTCATATGAAGAAGAGTTGGGAGTTTAATGTATATTCTTGATGGTTAATGTGTCTACATAAAGTGCTGATA
CATGTATTATATCACAGTATCAGGTTACTGGCATGGAGGACCATACACTTACAATATTGTAGCTGCTATATTTATTTAAGTAGATTCTGA
CAGTTACTGCACTAAACAGTAAGGAGATAAGCAGGATTCAAGGCTAGTGTTAGACCCTTTTTTTTCCTAAGAGTAAGGACACGGAATATC
AAAGTAACAAAGGGTGCTGCCATTTTAGTTTCAATTTAATATCAGGATATTCTTTGTTTTAGAAATGTAGATTTTGACTTTTACAGTTTG
AAAAAGGGTACCTCAGCCTCTTCAGTACTGGTTTTTTGGCACATTTCAACAGAAATATTAGATTCCCTTTCTTTTTCTTAATAGTGATCT
TCTAACAAGTTTCTTGGAAAAACTATCATTCTAAGGGAAATCCCTGTTTATAACCTATTAATATATTTCTATTCCTAGAAGAGAGTCTAG
CAGGGATTCTAGTAGGAATTACTGAGTGTTTTGGAAGGCACTTGATAGAGGCATCTCTGCTTTCCAGCACAGGGATTCTCAGCCTTCTAA
AGATCTAGACCAGTTTCCAAGCTAGCTTCTCCACAGCCCACCACTGCCTAGTGTTTGCTTGTGTATTCTCTAATGGATTTTAGGAGGATA
GGCCTTCTGACAGAGTCATGAAAGACTGAAGGCATGTCTAGGGAAATAAAACCTGACTTGCCCTTCAGCAGGAATGACTGGCAGCGGATC
TCTGTGTTCAAGGAAAGGGTGAGCGCTAAGCATGCCAGTGATGGATCCGAAGTATTTAGATGGATTGCAGACCAGGAATTAGAGACCGTT
TGTGACTCAAGGAACTTGATGGATCTGTTTAGAGCCCTACATGAATTTGCCAAGGGCAGTGATTTTTATGAAATTCAAGAAGCAAACGAC
TTCGATACAGCTAGAATATGTTGCAGTCTTCCTATTTCAAACTTGATTTTAATATTTTTACCAAGAAGTTTAACTGACAACTCTGCAAAA
TTTTCATTCAGTATCATTAAACCTGAGTTAAATGTTTGCTTAGCTTATCCTCTTAGATGTTCTTCTGTTGAACAGGCAGGTTGCCCTTAA
CAGTAACTTGCTACTTAAATTACCTTTTATTAGTTAGTCAAGCTGCAAAAATATCATTAGTGTGGCGTCTTTATTTTGGCTTTATCCATA
TGAAGTATTCATTATTTTCATTCTTTTTGAGAATTCATAAATGTCTTAAAGCTTCAGTAAGAATTGTTGGGAGGTTTGACATCAAGTAAC
GCCTTCCTGTGTAGCAGTATAACCCTAATTTAGAACTCTTGTTTTCCTATTTCAGTCCTCATATTTGATCATAGAAAAGCACTTTTGTGA
TTCTATAGGAGTCAAAAAATCAGCCAAGAGTAGGTAAGTCAGTCAGCACAGAAATCAGAAAGTGAGAATTTTCTCCAAAAAATCTTTTTA
AAAAAGTCCTGCTTATACTAAGAACATTCTTGATCCGTTGCAGTGTTAGAAATGACACTGTGATTAGTGAAAGCCAAGCTGAGTCCCAGG
AAGCAGGGAGGGGGAGTGTGTGTGTGTGTATATGTATGAGTGTGTATATATATAATCTCACACACACACACAAAGGGAAAAATTATTTTG
ACTTTTTTCCTACTTTTAAAATGGTACATTTAAGTTTATAATTTTCCATGTCAGTCAACATAATTTTTTAAACTAAGGTATAATGGTCAA
GGCTTGTGCTAATATTACCTACTACTCATTGAAATTTATATTACTTTACCCATCAAAACTAGTACTCCAGATGTTTACATCATTGATTAA
ATCTCAAGAATCTTTTGTTCTTAAAATATGGAAGTTAAAGATTTTAATTTGAATTAAAGATAGAAGGATGGTAAATTCAATATAGAGGGT
TGAGATTTACCAGTGAGAAACCCTGTTGAAGTATCAGGTAAATGGTGTGACAAAATTAGAATCCTGTCAAATCACCTATCCAGCCATCGG
GGTCCCTTCCTTTTTTAGACTAATTTCTAAGGTAACCAGAATCTAATGTATCTATGTTAGGGTCTCAGTAAAGCAAAGACGTTTGTCAGG
GCGTAGACTCTTGAGTTAAATTTTTTAATCATTTTTTAAAGCAAGGCGGTTCTTAGAAAGTGCCTTTTCAGAAGATGGTGCTGTAGATTT
TTATTTTTCAAGTAGCACGAAGCTAAGAATTTTAAAGATAAATTATTTTAGAACTCCAAGAGTGTGACAGTTTCATAAAAATAATGTTAG
TTGTTGTCTTGAATCTCGTCCAAGGGAACCAAGGAAAGCTTTTATGCAGTAAAGTATCTAGGTAAATGCTCACCAAATTTATTTTGTAAA
TTTGAAAACAAAATATTTAGTAGAATTACCTCTTTTAATTCCCAACTGTGTTGGAGGAAATCCATAATGCACATAAAACAGCAAACCTAC
TTAACTTTTTAACAAGATTATGGGTATAGTACCAATGTCCAAAGGGAAATGTAACTTGCCTGGAATCATAGGCAACATTTTCTAATTAAT
CTTTTTTTTTTTTTTTTTTTTTGAGACAAAGTCTTGCTCTGTCACCTAGGCTGGAGTGCAGTGGCTCAATCTCAGCTTACTGCAAACTCC
GCCTCCCGGGTTCAAGTGATTCTCGTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCATGCACCACCACACCCGGCCCTAATTAGTCA
TTATTAAGGAGGACTGCTCATAAAGGCAGTACCAAATCATCATTCAGATCAGCTTAAGTGAGAAAGCAAAATGATAATCTCTATTGTTAG
AGAAATTTTCTTTTCTAGACACCAAGGAATATTTTAAATGATTTTTTATTTTTTCTAGGATGCAGGAACTATGAAAAATGATGACAAGGC
ATTTAAAAGGGTATGATCAGTTAAATAGAAGTAGGGTCTGCAAATTGTGCTTAAGGGGAAATAAGCAAAAGAAAGGAAAATAGTAGAACC
TTTCATACTAATTAGAAATGTAGTTACCTACCAGAGGGCAATTTTGCTCCATACCAGGAAGCAGTAAATAGCAGTAAATGATCACCTAGG
CACTTCTTTCCTGTGAATTTGGTGAGCATTCTTCCAGAAAAGAAGACTAAAAGCAAACAACAACAACAACAAAAAATACCACACCTCAGT
AACCTTGTATGCTGCATTATATAATAATGATAGTAAAATTATATTGTTTGGAGTGTACTGTGTCTGTTTGCAAATATACATGCACATTAA
ACTTTTTTGTTTTTATAATGTCTTAATAGCAATTATGAGTTTATTTTTGTTAAGATTAATTTTTCTATTGTGATGTTTATATTTATTGGC
AATTTGTATGCAACTTTTATATTTTGCTTGTCGGTTTTAAGGTATTTTATTTTTATAGATATTTCTAGCTTTCCTCATTCTTTGTAATAG
CAGCAAAGATTAAGATGGAGTGTTAATATACCAACCAAACTACGAATTCCATAAACTCTAGAGTTTGGATTTTTACCAATAAACCATTAA
CACTATTTTGTAACTTAGAATATTTAATGTTGTTTATATAGTGGGCATTAAAGACAGTCTTTAGACAGATTTCTACATGTGGAGGGGAGG
TGGGGCTTTCCTGTAAGTTTGATCCTTTTTTTCCCCTTTAGTAGCAAACTAACATAACAGATTGGATTTATTTTACCTGACTACAGTTTT
GGGGAAACCTGTCAAATAAATAATTGTTACATGCCTTTTTTTTTTAAATTTAAGCACATTGAAACTGCTTAAATGGTCACATTTTTCAGC
ATTAGGATTAAGATACCATTTTTGTAGGCCTGGAAAACAAATAGCAAATGATTCAAAATTCATTGAATTGACTTTGAAATGAAACTTTTC
CCCCATAATTTGTTATATGGAAGATTTGCTACCCTGATCTTTTCCCTAGCATACTTCTAAAGTTGATTGAATCCCTGAGTATCAATGAAG
AAATCAGAGTTTAAGTGGCTAGGGAGAGCCAGGTATAAAGACTGATTAATAGAGTACTTCAGCTAATTAAAAATTTAAATAGTAATAATT
TATGAATGTGAATAAATTGGAAGGCAGCAAAAAGCATGATTATAGAATATTAAGTTCAATTATATATAGACAGTCCAGTTTCCTAGTGAA
TAGGTCAAGATTATTTGTTTTGTTTTGTGGCACTATCATAGTTCACTATAACTTCAAACTCCTGGGCTCAGGCTATCCTCCCACCTCAGC
CTCTGAAGTAGCTGGGACTACTCACATGCGCCACCATGCCCAGCTAATGGTTTTTTTCTTTAGAGATGGGGGTCACTATACTGCCCAGGC
TGGTCTTGAACTCCTAAGCTCAAGTGCTTCTCCCACATCAGCCTCCCAAAGTGCTGGGATTACAGCCATGAGCCACTGCATCTGGCCAAG
ATCAAGATTATGGATATTGGTATGTTAACTTTTAAAATAAAAGTACATGGGCTGGGCGCAGTGGCTAACGCCTGTAATCCCAGCAATTTG
GGAGGCCGAGGCAGGCAGACCACCTGAGGTCAGGGGTTCGTGACCAGCCTGGCCAACATGGCGAAACCCCGTCTCTACTAAACATACAAA
AATTAGCTGGGCATGGTGGCACATGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCACTTGAACTCGGGAGGCGGAGGTT
GCAGTGAGCCAAGATCGCGCCATTGCACTCCAGCCTGGGCAACAAGAGTGAAACTCCATCTCAGAAAATAAAAATAAAAATAAATAAAAG
TACATGAAAAAAGTATATTCCCTTAAGCAGGTAAAATACTTGCATTGTATTTTTACATCATGAATTTGCTTGTTAAGAAATTTCTTTTCT
GTAAGTGGTTAAAAGATAAACTGTATTCCATCCTCTGGGTTTTCAATTCTAAATTATTGGAGCTCAATGTATGACATTTTACTGTAGTGT
ATTCCACTGAGAGGCAAGGAAATGGGAAAGTGTCAGGTAATTATAAATGGGAAAATTTTATTTTTATATGATGTAAAGTTTTACAGTTTA
AAATAGATCAGCATGTGATTTCTTGTAGAGATTAGCCATTTCATTTCTTTTTGCATTTTTGCCAGTTACATTAGTTTGCCCTATGATATA
CTATTCTGAGATACTTCAGCCCCGCACACATCAAGTACTAATTGTATACAGATAGTACAGATTTGTACTCTGATTATAAGAATTTGTTAC
TACTAATTAAAAGCAAATTAATGTGGCTGGGCGTGGTAGCTCACACCTGTAATCCCAGCACTTTGGGTGGGCGGCTGAGGCGGGCGGATC
ACGAGGTCAGGAGTTGGAGACCAGCCTGCCCAATATGGTGAAACCCTGTCTCTACTAAAATTACAAAAATTAGCTGGGCTTGGCGGTACG
TGCCTGTAATCCCAGCTACTGGGAAGGCCGAGGCAGGAGAATGGCTTGAACCCAGGAGGCGGAGGTTGCAGTGAGCCAAGATCACACCAC
TGCACTCCAGCCTGGGCGACAGAGCAAGACTCCGTCTCAAAAAAAAAAAAAGCAAAATATTTTTGCTGTGATTGTATGTCCCCTTTTAAG
GATATTTATTGCGCTTATAACCTTAATAGTTGTATTCATTACATTTCAACATGTCCAAGGTTAGCAGACATGTAGTTCCTGAAAACCAAC
ATTTTAAAAGTTGCCTCTGGGCTGGGCATGGTGGCTCACGCCTGTAATCCCTGCACTTTGGGAGGCCGAGGTGGGCGGATCACGAGGTCA
AGAGATGGAGACCATCCTGGCCAACATGCTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCTGGGTGTGGTGGCACACGCCTGTAG
TCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCACTTGAACCTGGGAGGCGGAGGTTGCAGTGAGCCAAGATTGCACCGCTGCACTCCA
GCCTGGCAACAGAGCAAGACTCCATCTCAAAACAAACATACAAACAAAAAAAGGTGCCTCTGGTCCTGTGTTTTCTTTTTCCTTCTGAAA
GTTCATAGAAACCTGGCATATAGAGCTTATTTTGCTGTTTTAACTGGTTGGCTCCACAAATCCTGCTACCTGACATCAGTACAGCTTGAC
CGCAGTGAAGTACTTGATGGCTTGTTCATGTTTAGTTCACCTCTTTAGAAAGAAAGCTTTGTGGCCAGGTGCAGTGGCTCACACCTGTAA
TCCCAACACTTTGGGCAGCTGAGGTGAGCAGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGCAAAACCCTGTCTCTT
CTAAAAATACAAAAATTAGCCGGGTGTGGTGGCGGAGGATGCAGTGAGCCAAGATCGTGCCACTGCACTCCAGCCTGGGCAACAGAGTGA
GACTCTGTCTCAAAAAAAAAAAAAAATCGTTGTGCAGTAATAGATCATCCCAAAAAAGAATTGCCATGAACAGCGTTATGCGTAGAAAAC
AGATGGAAGTGTTGGTCATTAGAGCCTTGCTTTTTAAATTTTATTCTTTCCAAAAATTGGCGGTATGCTATCTATAATTTTATGTTTGAT
GTTGAAGAGGCAACACCAGAGACTAGAGAGGGAGATTACTCTGATATTTAGTGCCTAAAACTTTCATCTTGGCCGGGCACGGTGGCTCAC
ACCTGTAATCCCAGCACTTCGGGAGGCCGAGGCAGGCTGATTACCTGAGGTCAGGAGTTCGAGACCAGCCTGGACAACATGGCAAAACCC
GTCTCTACTAAAAATACAAAAATTAGCCAGGCATGGTGGTGGGCGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCGAGAGAATCGTTT
GAACCCGGTAGGCGGAGGTTGCAGTGAGCCGAGATCATGCCACTGCACTCCAGCCTGGGCGACAAGAGTGAAACTCCGTCTCAAAAAATA
ATAATAATTTTAAAAATAAAAGACAAAACTTTCATCTTTATTTCATGGCTTTATTTCATCTTTATTTCATTTTTGGTTGGGAAAACAAAC
AAAAATCTCTTAAGTTAGTCCTTTAATAGTCTTTTTAGAACCAAAGAAGGAAAGACTGCAAAAATGTTGCATACGTGACTCTTTATTGTC
AGAATCTGTAGAAACTGGAGGTCTTTGTAAAGAAATAGACTAGTAGGATTGTGAGAATATATAGTGAGGGGGGATTTAGGATAAGGCTTC
CTTGCTGGGATCCTTGGACAGAAACCTTACAATTGTTTAATATTTGCAGAGTAAAAGAGCAGCTATTGCTATTTGAACCTACAGAAGAGA
CCTAAGACGAGCGTCTCTGTAATCTAAATTTATATGATAATGTTGTCCCAGACCCAAAGGCACACCTATTCTCAGTAACTTAGAGAAGTC
TTGGAAGTTGCTTCTGAATTACAGTAAAGAAATTAAATGAAGTCTTTATCCTTAAATAGGGCCAGGCATTGCTATCAACATAGTGTCTTT
GGTTTTCCCCTTTAAATAGAAAACACCAAGCAGGGCCTTTCCAGACAATGTAGTCTTTCCTGTAAAGAAAATGGTTTTGGTGTGGGATTT
GGTAAAAACACTGGTTAGTTTGTAATGAAGAAAGAATTTTGGCATAGACAGTCCGACCCAGTTCATGGATACAGTTTGATCCCAGGGAGT
TTAACAAAAGGAAGCTTTGGTTTTGCTAGCAACAGACTTGATCTTCTATAGTAATTAATTGCAATTAAGGTTTTCCAGGAGCTTTCTCAT
TTCTTAGCCCAGGGTCCAACCCCATTCCCTCTTTAAAAAAGAAAGAATAGGCCGGGAGCAGTGGCTCATGCCTGCAATCCCAGCACTTTG
GGAGGCCAAGGCAGGTGGATCACAAGGTCAGGAGTTTGAGACCAGCGTGGCCAATATGGTGAAACCCTGTCTCTACTAAAAATACAAAAT
TAGCTAGGCGTGGTGGCAGGCGCCTGAGGCTGAGGCAGGAGAATCCTGCTAGTCTGAATTACAATAAGGAAATTAAATGAAGGATTTATC
TTTAATAGAGCCAGGCATTGCTATCAACATAACATGTTTGGTTTTCCCCTTTAAATAGAAAACACCAAGCAGGGCCTTTCCAGACAAGGT
AGTCTGGAACCCAGGAGGCGGAGGTTGCAGTGAGCCGAGATCCCACCATTGCACTCCAGCCTGGGTGGCAGAGTGAGACTCCGTCTCAAA
AAAAAAAAAAAGAAGGAATAGGAAAAGGACTTAGAGGCAGTTGATATAGAATTCTACTGGGGGTAAATGACACTCTCAAAATACTTGGGA
AAGAAGAATCACATGCCACAAGCTATAGCTTGATTAATATTTTAGCATGTTTTCCATGTTTGTATTCTAAAGTTTGTTTCCTTTGACATT
CCATTATCTTACTTACTAGAGTGCCACCATTCTTATTTGTAATACAATCAGTGTTTTATGCCATTTGTGAATCACACAATTGTTCTTTTT
TCCCCATCACACACACTCACACACAAACACACACACTGTTAAAAATAAAAGAGGGGAAGGATAAAACAAAAATAGATAGAATGATGATTA
TTACAATGTAACTTTAACATATATGAAGAGAAATTCTAACTCAGTTAAGTGAGAATTAAGATTGAAAGTATTAATGTTGCAAGTATTATC
TCTAGCCATGGAATTTTTTGCTGGCTATAGAATGCTAATGTGAACAGAGTATATATCAGGAATATGATGTATTATGGCACAGTGATAATA
TTATTGTTGATATTAGCCAGATGTGGTGGTTTGCACCTGTAGTCCGAACTTCTCAGGAGGATGAGGCAGGAGGATAGTTGAGCCCAGGAG
TTTAAAGCAAGCCTGGGCAATACAGCAAGACCCCAATCTTTAAAATAAATAAATAAATAAGAATTATTCTTGAAAGTAATATTCTAACCT
TCTGCCAACCAACAGAGATCCTCATATTCTTAAAGAAAATTAATATAGCTTATGGTTTTGATAAATTGGACTCTGATTTAAACTTTAAAA
TGTTATGACTTTTATTCTGATACATGGCTTCTAAAATATGTAAAAAATTATATTGAATGAATTAATACTTAACCTGTTCATTTCTCTTAA
TTTATGTATTTATTCTGACTTTATTATACAGCTTATGTCTCACATCTGCCTTCTTGATATGTGCAAAATATTGTGTAAAAATAGTTTAAA
ACTCATCCCAGTTCCTAGTCAAGCGTGGGCTATAAGAGAGAAGGCTTAAGGTGTTCTTTAATGGAGGAACTTTTGAAAGATCACAAATGG
AAAAAGCCTATTGAGAATTTATTGCCTTTGAGAGTAGAAAGGGCTCTAGAATATGAGCCAGAGACTTGGAATTTAGTAATAGGTCTCCCA
CTGATTTGCTCCGTGTCCTTAGGCAATTCGTTTAATCTCTGTGTGCCTAGTTTCCCCTTGTAAATAAGAGTGGTAATACCTGTCCTCACC
TACCTCACTAAATTGTTGGAGTTCTTTTGTTCTGAGTCAGGGTCTCACTCTGTTGCCCAGGCTGAACTACAGTAGTGTGATCATAGCTCA
CTACAGCCTCCAACTCCTGGGCCCAAACTATCCTCCTGCTTCAGCCTCCCAAGTAGCTGGGACTAGAGGTACATGCCACCACACCCAGCT
AATTATTTTCTTTTATTGCAGAGATGGGGTCTCACATGTTGCCAAGGCTGATCTCTAACTCCTGAGCTCAAGCAGTCCTCCTGCCTCAGC
CACCCAAAGTGCTGGGATTATAGGCATGATCACTAAATTGTTGTAAGAATAAGATAATGTTTGCGGAAGCATTTGAGTTCTCCAAAGGAA
AAGCTATTCAGACGTTCAAGATAATAGAAGAGTGTTGTGTGAAGGATTCCTTTCCAGTTTGCCTCTGTGAAAATGTCTTTGTTGTAGATC
ATTTTATGAAATAGGAATAAGAGAAACATAGGCCTTATCATGGTGTAGTGTTCACTTACAAACATATCCTGTTGTTTCTTCCCTGCAAGA
TATCCAGCACACAGGCTGAATTTTTCTTTATAATAATCCTTGGCAAAAGCATAACTTTTCAAAAACCAAATGATTTTAGTGGTGCTATGG
CAGCTGCAGTTTTGAGTTAGATTAATGTGGTGAAAACCATCAAATACTTAGAAATTGACTGGGTGCGGTGGCTCATGCCTGTAATCCCAG
CACTTTGGGAGGCCGAGGTAGGTGGATCACTTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGCAAAACCCCGTCTCTACTAAAG
ATACAAAAATTAGCTGGGCACGATGGAGGGTGCCTGTAATCCCAGCTACTCGGGAGGCTAAGGTGGGAGAATTGCTTGGACCCAGGTGGC
AGAGGTTGCAGTGAGCCAAGATTGTGCCACTGCACTCCAGCCTGGGCAACAAAGCGAAGCTCTGTCTCAATAAAAAAAAAAATAATAATA
ATAAAATACAAATACTTAGAAATTAACTTCGCCTTTGCCTTCAGGCACTTTTGCTACATGTTAGCATCAGAGGCTATTGTACAACTAGAT
GGTTATTCCCTGTTTCTTGGCCGATTTTTGGTACCTTTCTTTGAAGAAGAGGGTTAGATTTTAAGAAAGAAAGTGTGCTTATTTCACTCA
TGTCTTTGCAGAATTTAACTTTGCTTTACTTTAAAAATTCCAATCATCATGTACCTATAAAGGTTAAAATATAGTGAAAGTTTCTGCTTC
ATGTGAATTCAATTCTGAGCACCTGCAGGTCATATCAGGTGTCTGATGCAGTTACCTTTATAGATCGTGGCAGGTCCTTACATTTCAACA
GGCTTATGCATTTCCATGGGGGGAAGAGATTCTGTTTCTAGGAAATTACAAAGGGCACACCACTGCAGGGAGTGTAAACAATTCTTTGTT
GCAACAGACAAGATTTTTTTTAAAAAAAGAAAAAAGGATGCATTTTAGGTACACAGGGTATGGACGCATTCAACATTTACTTTTATCTCC
ACAGATGCCAACCTCCCCTTGTTGCAGGCAGTTGGGCTTTTCCAACTCATTGCTAACAAAGCTGGCATCTGCATTAATTTCAATGAGAAT
TTCAAGTACTGAAGATGAAAAGTTGGGGAGATTCATGTTTGAAAAATGAAAAATGAACAAAAAATCCACCTTGTGCAGTGAGATAGCTAA
CGCTGATATATCAGGAATAATTTTAAACTATTTTTGCTGTAATGTGTAGCTTTAATGTCTCTTTTCAGTTATGGACCCATAAAAGTATTC
CTATATCTTGTGAATAAAGATCATTCTTGTGGACTAGTACGTGGATGCATTCATAGGCTTTGGGAAGCAGTGGTGTGCGTATGTGTGTCT
ATATCAATATTTTATGTTTATAACTCTGCGTATTAAGTTTATATAGAAAAAAATAATGTCTTTCTTTAGTGTTTGGGGGACTCAATGGTA
ATATGACCATTGCAGTGTAATCTGACTGCTCACTCTAGAGAACACTTCTGTTATACACAATGCACATACAAACATACACCCCTAAAGCGT
AGCTAACTGCTCCCACTAGATAATTGCTGCTAAAAACAAAACAAAACAAAACAATACAAAACAAAAAAAACCCTAAGTAATGGAGGAAGA
AATAGCATTCTTTTAAAAGGGGCTTTTCTGAAGAGTAAAATGTAAATACAGGACATGTGGGGAGGGTGGGGCCGCCTGCAAAATGTCCTG
AAGATGGACAAATAGCCTTTTAAATTCTACTTTTTAACCATCTTTACCGTGTGTGCCTATTTGTATTGCAGATGTGAACTACTATTTTTG
GAGGTTGATATCAGTATGTTTTGAAACTGAATTATTACATAAAATCAGAGTAACCTCTTTCTCCATCCTCCTTTTCCACACTATTCTTGC
CAAATATTTCTACTGAAACCCAGTTTCAGCAAGGCAAAATGATGGGACTCTCAAACCTCCCTCCTCATCTTCCCTTCCCCTCTGTCTTAT
GCCTGGCCTGGCCTTTTTTGTTGTTGTTGGCTTTTCATAAGTAAGAAAAATTTATTGTAGTATTTCAAGACTGCAGAATTTCAAGTGTAT
ATCTATAAATCTTTTTTTAAAATCTTCGGCTACACAGTAACATCAATTAAAACAGAAGAGTGAGTCTAAGTCTGTAATATGCTGTAGGAC
CAGATAAGATTTTGAATGAGACTAAACTTGACTGCCATATTTTAAGAGGAAATTGAAACTTTATGGTGGAGAATGGATGAGAGCAAGTCT
ATGATATATATGTAGTCATTGTATAATTAGAAACACCAAATGCTGAATCCTATCACTGTGTTCTTGGGGGCCAGGCCTTGGATTTGGTTG
TCATTTAAACTCCTTGAAGATTATATGTAATTATAATGAGCAGAAGGCAAATAAAGTTTTTGAACAAAAGTCCTTGTTTTCAGTATTTAA
AATTTGGTAATATATTTTCTTTTTCAGTTAAACTATCTTCCCCACAAAAAATATTATACTTCAGTTAAACTATCTTCCCCACAGAAATTA
TTATACTACGAACAAGTTATGAGTGAGACTGAGAAGCTTGAAGAAGCTGGTTTTTAAGCAGCTCATATAATATTTTGTGTTAAAGAAAGT
GTCATTGTTTCCTGTTGGGAGGCAAATAACAACAACAACAAAAGAAATTGTCATGATTCTTTCTGAGCCAAACTGTCACGAAATGTTCTG
TGACAGAACCACTACTCTTTTTTCTGCCATTCTGCCTACTGGAGAGTTCTATGTTGTATTTGTTTTTAATCCTTGATTTTAAAAATATTA

>In-frame_ARHGEF2_ENST00000361247_chr1_155927504_-_AGO3_ENST00000397828_chr1_36432556_+_2683nt
GAGACCAACGCGTGCGGGCCGAACCCCTCCCCCCGCCTTCCCCCAACAATACAGGACGCCGGGGTCCGCGCCGCGTCCTCCCTGGTCCCC
CCGTCCGATTATGTCTCGGATCGAATCCCTCACGCGGGCGCGGATCGACCGGAGCAGAGAGCTGGCGAGCAAGACCCGGGAAAAGGAGAA
GATGAAGGAAGCCAAGGATGCCCGCTATACCAATGGGCACCTCTTCACCACCATTTCAGTTTCAGGCATGACCATGTGCTATGCCTGTAA
CAAGAGCATCACAGCCAAGGAAGCCCTCATCTGCCCAACCTGCAATGTGACTATCCACAACCGCTGTAAAGACACCCTCGCCAACTGTAC
CAAGGTCAAGCAGAAGCAACAGAAAGCGGCCCTGCTGAAGAACAACACCGCCTTGCAGTCCGTTTCTCTTCGAAGTAAGACAACCATCCG
GGAGCGGCCAAGCTCGGCCATCTACCCCTCCGACAGCTTCCGGCAGTCCCTCCTGGGCTCCCGCCGTGGCCGCTCCTCCTTGTCTTTAGC
CAAGAGTGTTTCTACCACCAACATTGCTGGACATTTCAATGATGAGTCTCCCCTGGGGCTGCGCCGGATCCTCTCACAGTCCACAGACTC
CCTCAACATGCGGAACCGAACCCTATCCGTGGAATCCCTCATTGACGAAGCAGAGGTAATCTACAGTGAGCTGATGAGTGACTTTGAGAT
GGATGAGAAGGACTTTGCAGCTGACTCTTGGAGTCTTGCTGTGGACAGCAGCTTCCTGCAGCAGCATAAAAAGGAGGTGATGAAGCAGCA
AGATGTCATCTATGAGCTAATCCAGACAGAGCTGCACCATGTGAGGACACTGAAGATCATGACCCGCCTCTTCCGCACGGGGATGCTGGA
AGAGCTACACTTGGAGCCAGGAGTGGTCCAGGGCCTGTTCCCCTGCGTGGACGAGCTCAGTGACATCCATACACGCTTCCTCAGCCAGCT
ATTAGAACGCCGACGCCAGGCCCTGTGCCCTGGCAGCACCCGGAACTTTGTCATCCATCGCTTGGGTGATCTGCTCATCAGCCAGTTCTC
AGGTCCTAGTGCGGAGCAGATGTGTAAGACCTACTCGGAGTTCTGCAGCCGCCACAGCAAGGCCTTAAAGCTCTATAAGGAGCTGTACGC
CCGAGACAAACGCTTCCAGCAATTCATCCGGAAAGTGACCCGCCCCGCCGTGCTCAAGCGGCACGGGGTACAGGAGTGCATCCTGCTGGT
GACTCAGCGCATCACCAAGTACCCGTTACTCATCAGCCGCATCCTGCAGCATTCCCACGGGATCGAGGAGGAGCGCCAGGACCTGACCAC
AGCACTGGGGCTAGTGAAGGAGCTGCTGTCCAATGTGGACGAGGGTATTTATCAGCTGGAGAAAGGGGCCCGTCTGCAGGAGATCTACAA
CCGCATGGACCCTCGGGCCCAAACCCCAGTGCCTGGCAAGGGCCCCTTTGGCCGAGAGGAACTTCTGAGGCGCAAACTCATCCACGATGG
CTGCCTGCTCTGGAAGACAGCGACGGGGCGCTTCAAAGATGTGCTAGTGCTGCTGATGACAGATGTACTGGTGTTTCTCCAGGAAAAGGA
CCAGAAGTACATCTTTCCTACCCTGGACAAGCCTTCAGTGGTATCGCTGCAGAATCTAATCGTACGAGACATTGCCAACCAGGAGAAAGG
GATGTTTCTGATCAGCGCAGCCCCACCTGAGATGTACGAGGTGCACACAGCATCCCGGGATGACCGGAGCACCTGGATCCGGGTCATTCA
GCAGAGCGTGCGCACGGAGGTGGTTGACTCAATGGTTCAGCATTTTAAAGTAACTATATTTGGAGACCGTAGACCAGTTTATGATGGAAA
AAGAAGTCTTTACACCGCCAATCCACTTCCTGTGGCAACTACAGGGGTAGATTTAGACGTTACTTTACCTGGGGAAGGTGGAAAAGATCG
ACCTTTCAAGGTGTCAATCAAATTTGTCTCTCGGGTGAGTTGGCACCTACTGCATGAAGTACTGACAGGACGGACCTTGCCTGAGCCACT
GGAATTAGACAAGCCAATCAGCACTAACCCTGTCCATGCCGTTGATGTGGTGCTACGACATCTGCCCTCCATGAAATACACACCTGTGGG
GCGTTCATTTTTCTCCGCTCCAGAAGGATATGACCACCCTCTGGGAGGGGGCAGGGAAGTGTGGTTTGGATTCCATCAGTCTGTTCGGCC
TGCCATGTGGAAAATGATGCTTAATATCGATGAAAGAGACCTCTGGCAGCAGTGTGGAGAATAGATAGAGGAGAAAAAACTAATCTGAGA
AGCCAGTTAGGAGGCTTTTCAATCACTAGTTCAGGTTTCAGTCTACATGTTACTTCCTTGAGAAGCAGTGTTTGACACCCTTCTCCCCCA
ATCCAGCCATCCCCCAAGTCTGAGTTAGGTATTTCTCTTCTGTATTCCCATAGCACAGTGTAATTCCCCTATAATAGCATGTATCACCTT
GAATTATGGGTGTTTATTGTTCTGTCTCTCCTGTTAGAACGAAAGCTCCATGAAGGGATTGTCATTTTATTCACCAGTGTACCCTCTATG

>In-frame_ARHGEF2_ENST00000313667_chr1_155927504_-_AGO3_ENST00000324350_chr1_36432556_+_2968nt
ATGTCTCGGATCGAATCCCTCACGCGGGCGCGGATCGACCGGAGCAGAGAGCTGGCGAGCAAGACCCGGGAAAAGGAGAAGATGAAGGAA
GCCAAGGATGCCCGCTATACCAATGGGCACCTCTTCACCACCATTTCAGTTTCAGGCATGACCATGTGCTATGCCTGTAACAAGAGCATC
ACAGCCAAGGAAGCCCTCATCTGCCCAACCTGCAATGTGACTATCCACAACCGCTGTAAAGACACCCTCGCCAACTGTACCAAGGTCAAG
CAGAAGCAACAGAAAGCGGCCCTGCTGAAGAACAACACCGCCTTGCAGTCCGTTTCTCTTCGAAGTAAGACAACCATCCGGGAGCGGCCA
AGCTCGGCCATCTACCCCTCCGACAGCTTCCGGCAGTCCCTCCTGGGCTCCCGCCGTGGCCGCTCCTCCTTGTCTTTAGCCAAGAGTGTT
TCTACCACCAACATTGCTGGACATTTCAATGATGAGTCTCCCCTGGGGCTGCGCCGGATCCTCTCACAGTCCACAGACTCCCTCAACATG
CGGAACCGAACCCTATCCGTGGAATCCCTCATTGACGAAGAGGTAATCTACAGTGAGCTGATGAGTGACTTTGAGATGGATGAGAAGGAC
TTTGCAGCTGACTCTTGGAGTCTTGCTGTGGACAGCAGCTTCCTGCAGCAGCATAAAAAGGAGGTGATGAAGCAGCAAGATGTCATCTAT
GAGCTAATCCAGACAGAGCTGCACCATGTGAGGACACTGAAGATCATGACCCGCCTCTTCCGCACGGGGATGCTGGAAGAGCTACACTTG
GAGCCAGGAGTGGTCCAGGGCCTGTTCCCCTGCGTGGACGAGCTCAGTGACATCCATACACGCTTCCTCAGCCAGCTATTAGAACGCCGA
CGCCAGGCCCTGTGCCCTGGCAGCACCCGGAACTTTGTCATCCATCGCTTGGGTGATCTGCTCATCAGCCAGTTCTCAGGTCCTAGTGCG
GAGCAGATGTGTAAGACCTACTCGGAGTTCTGCAGCCGCCACAGCAAGGCCTTAAAGCTCTATAAGGAGCTGTACGCCCGAGACAAACGC
TTCCAGCAATTCATCCGGAAAGTGACCCGCCCCGCCGTGCTCAAGCGGCACGGGGTACAGGAGTGCATCCTGCTGGTGACTCAGCGCATC
ACCAAGTACCCGTTACTCATCAGCCGCATCCTGCAGCATTCCCACGGGATCGAGGAGGAGCGCCAGGACCTGACCACAGCACTGGGGCTA
GTGAAGGAGCTGCTGTCCAATGTGGACGAGGGTATTTATCAGCTGGAGAAAGGGGCCCGTCTGCAGGAGATCTACAACCGCATGGACCCT
CGGGCCCAAACCCCAGTGCCTGGCAAGGGCCCCTTTGGCCGAGAGGAACTTCTGAGGCGCAAACTCATCCACGATGGCTGCCTGCTCTGG
AAGACAGCGACGGGGCGCTTCAAAGATGTGCTAGTGCTGCTGATGACAGATGTACTGGTGTTTCTCCAGGAAAAGGACCAGAAGTACATC
TTTCCTACCCTGGACAAGCCTTCAGTGGTATCGCTGCAGAATCTAATCGTACGAGACATTGCCAACCAGGAGAAAGGGATGTTTCTGATC
AGCGCAGCCCCACCTGAGATGTACGAGGTGCACACAGCATCCCGGGATGACCGGAGCACCTGGATCCGGGTCATTCAGCAGAGCGTGCGC
ACGGAGGTGGTTGACTCAATGGTTCAGCATTTTAAAGTAACTATATTTGGAGACCGTAGACCAGTTTATGATGGAAAAAGAAGTCTTTAC
ACCGCCAATCCACTTCCTGTGGCAACTACAGGGGTAGATTTAGACGTTACTTTACCTGGGGAAGGTGGAAAAGATCGACCTTTCAAGGTG
TCAATCAAATTTGTCTCTCGGGTGAGTTGGCACCTACTGCATGAAGTACTGACAGGACGGACCTTGCCTGAGCCACTGGAATTAGACAAG
CCAATCAGCACTAACCCTGTCCATGCCGTTGATGTGGTGCTACGACATCTGCCCTCCATGAAATACACACCTGTGGGGCGTTCATTTTTC
TCCGCTCCAGAAGGATATGACCACCCTCTGGGAGGGGGCAGGGAAGTGTGGTTTGGATTCCATCAGTCTGTTCGGCCTGCCATGTGGAAA
ATGATGCTTAATATCGATGAAAGAGACCTCTGGCAGCAGTGTGGAGAATAGATAGAGGAGAAAAAACTAATCTGAGAAGCCAGTTAGGAG
GCTTTTCAATCACTAGTTCAGGTAAGAGATGGTGATGGTCTAATGTGGGATGGAGAGGAAGGATTAAGCTGAAAAAATAGGTTTAAGAAC
CATGTCCAGAAAAAAAAAACTTTGGGTGTAGTACTGGTACATGGAACGGATTGGAAAAAAATAGACCAGAGCTTTACTAGATTTTTGAAA
GAATTGTTTTTGCAAATAAACTACAAGCCTGGCATATCAGTCAAGGTTCAGAACCTAGAGAAGCAGAACCAGTACGAAGTATAGAGAGAG
AGTTTATGCAATTGTAGGGGCTAGCTAGGCAAGTCTGAAATTTTGGGGGCAGGCTGTCAGGAAGGGCAGGGAAATTCAGGCATGGGCTGA
AGCAGTTATCTATAAGTGGAATTTCTTGCTCTCAGGGAAGCTTCAGCCCTACTTTTAAGACCTTTCACCTAATTGAATCAGGCCCATCCA
CATTATTCAGGATAATCTCCATTACTTAAAGTCAACAGATTATGGATTTTAATTACATCTACAAAATACCTTCATAGCAACACCTAGATT
AGTGTTTGATTAAACAAATGGCAGCTGGTAGCCTAGCAAGTTAACACATTAAAAACAACACCTGCCATGATGGCTTACACTTGTAATCCC

>In-frame_ARHGEF2_ENST00000313667_chr1_155927504_-_AGO3_ENST00000373191_chr1_36432556_+_20859nt
ATGTCTCGGATCGAATCCCTCACGCGGGCGCGGATCGACCGGAGCAGAGAGCTGGCGAGCAAGACCCGGGAAAAGGAGAAGATGAAGGAA
GCCAAGGATGCCCGCTATACCAATGGGCACCTCTTCACCACCATTTCAGTTTCAGGCATGACCATGTGCTATGCCTGTAACAAGAGCATC
ACAGCCAAGGAAGCCCTCATCTGCCCAACCTGCAATGTGACTATCCACAACCGCTGTAAAGACACCCTCGCCAACTGTACCAAGGTCAAG
CAGAAGCAACAGAAAGCGGCCCTGCTGAAGAACAACACCGCCTTGCAGTCCGTTTCTCTTCGAAGTAAGACAACCATCCGGGAGCGGCCA
AGCTCGGCCATCTACCCCTCCGACAGCTTCCGGCAGTCCCTCCTGGGCTCCCGCCGTGGCCGCTCCTCCTTGTCTTTAGCCAAGAGTGTT
TCTACCACCAACATTGCTGGACATTTCAATGATGAGTCTCCCCTGGGGCTGCGCCGGATCCTCTCACAGTCCACAGACTCCCTCAACATG
CGGAACCGAACCCTATCCGTGGAATCCCTCATTGACGAAGAGGTAATCTACAGTGAGCTGATGAGTGACTTTGAGATGGATGAGAAGGAC
TTTGCAGCTGACTCTTGGAGTCTTGCTGTGGACAGCAGCTTCCTGCAGCAGCATAAAAAGGAGGTGATGAAGCAGCAAGATGTCATCTAT
GAGCTAATCCAGACAGAGCTGCACCATGTGAGGACACTGAAGATCATGACCCGCCTCTTCCGCACGGGGATGCTGGAAGAGCTACACTTG
GAGCCAGGAGTGGTCCAGGGCCTGTTCCCCTGCGTGGACGAGCTCAGTGACATCCATACACGCTTCCTCAGCCAGCTATTAGAACGCCGA
CGCCAGGCCCTGTGCCCTGGCAGCACCCGGAACTTTGTCATCCATCGCTTGGGTGATCTGCTCATCAGCCAGTTCTCAGGTCCTAGTGCG
GAGCAGATGTGTAAGACCTACTCGGAGTTCTGCAGCCGCCACAGCAAGGCCTTAAAGCTCTATAAGGAGCTGTACGCCCGAGACAAACGC
TTCCAGCAATTCATCCGGAAAGTGACCCGCCCCGCCGTGCTCAAGCGGCACGGGGTACAGGAGTGCATCCTGCTGGTGACTCAGCGCATC
ACCAAGTACCCGTTACTCATCAGCCGCATCCTGCAGCATTCCCACGGGATCGAGGAGGAGCGCCAGGACCTGACCACAGCACTGGGGCTA
GTGAAGGAGCTGCTGTCCAATGTGGACGAGGGTATTTATCAGCTGGAGAAAGGGGCCCGTCTGCAGGAGATCTACAACCGCATGGACCCT
CGGGCCCAAACCCCAGTGCCTGGCAAGGGCCCCTTTGGCCGAGAGGAACTTCTGAGGCGCAAACTCATCCACGATGGCTGCCTGCTCTGG
AAGACAGCGACGGGGCGCTTCAAAGATGTGCTAGTGCTGCTGATGACAGATGTACTGGTGTTTCTCCAGGAAAAGGACCAGAAGTACATC
TTTCCTACCCTGGACAAGCCTTCAGTGGTATCGCTGCAGAATCTAATCGTACGAGACATTGCCAACCAGGAGAAAGGGATGTTTCTGATC
AGCGCAGCCCCACCTGAGATGTACGAGGTGCACACAGCATCCCGGGATGACCGGAGCACCTGGATCCGGGTCATTCAGCAGAGCGTGCGC
ACGGAGGTGGTTGACTCAATGGTTCAGCATTTTAAAGTAACTATATTTGGAGACCGTAGACCAGTTTATGATGGAAAAAGAAGTCTTTAC
ACCGCCAATCCACTTCCTGTGGCAACTACAGGGGTAGATTTAGACGTTACTTTACCTGGGGAAGGTGGAAAAGATCGACCTTTCAAGGTG
TCAATCAAATTTGTCTCTCGGGTGAGTTGGCACCTACTGCATGAAGTACTGACAGGACGGACCTTGCCTGAGCCACTGGAATTAGACAAG
CCAATCAGCACTAACCCTGTCCATGCCGTTGATGTGGTGCTACGACATCTGCCCTCCATGAAATACACACCTGTGGGGCGTTCATTTTTC
TCCGCTCCAGAAGGATATGACCACCCTCTGGGAGGGGGCAGGGAAGTGTGGTTTGGATTCCATCAGTCTGTTCGGCCTGCCATGTGGAAA
ATGATGCTTAATATCGATGTTTCTGCCACTGCCTTCTACAAAGCACAACCTGTAATTCAGTTCATGTGTGAAGTTCTTGATATTCATAAT
ATTGATGAGCAACCAAGACCTCTGACTGATTCTCATCGGGTAAAATTCACCAAAGAGATAAAAGGTTTGAAGGTTGAAGTGACTCATTGT
GGAACAATGAGACGGAAATACCGTGTTTGTAATGTAACAAGGAGGCCTGCCAGTCATCAAACCTTTCCTTTACAGTTAGAAAACGGCCAA
ACTGTGGAGAGAACAGTAGCGCAGTATTTCAGAGAAAAGTATACTCTTCAGCTGAAGTACCCGCACCTTCCCTGTCTGCAAGTCGGGCAG
GAACAGAAACACACCTACCTGCCACTAGAAGTCTGTAATATTGTGGCAGGGCAACGATGTATCAAGAAGCTAACAGACAATCAGACTTCC
ACTATGATCAAGGCAACAGCAAGATCTGCACCAGATAGACAAGAGGAAATTAGCAGATTGGTAAGAAGTGCAAATTATGAAACAGATCCA
TTTGTTCAGGAGTTTCAATTTAAAGTTCGGGATGAAATGGCTCATGTAACTGGACGCGTACTTCCAGCACCTATGCTCCAGTATGGAGGA
CGGAATCGGACAGTAGCAACACCGAGCCATGGAGTATGGGACATGCGAGGGAAACAATTCCACACAGGAGTTGAAATCAAAATGTGGGCT
ATCGCTTGTTTTGCCACACAGAGGCAGTGCAGAGAAGAAATATTGAAGGGTTTCACAGACCAGCTGCGTAAGATTTCTAAGGATGCAGGG
ATGCCCATCCAGGGCCAGCCATGCTTCTGCAAATATGCACAGGGGGCAGACAGCGTAGAGCCCATGTTCCGGCATCTCAAGAACACATAT
TCTGGCCTACAGCTTATTATCGTCATCCTGCCGGGGAAGACACCAGTGTATGCGGAAGTGAAACGTGTAGGAGACACACTTTTGGGTATG
GCTACACAATGTGTTCAAGTCAAGAATGTAATAAAAACATCTCCTCAAACTCTGTCAAACTTGTGCCTAAAGATAAATGTTAAACTCGGA
GGGATCAATAATATTCTTGTACCTCATCAAAGACCTTCTGTGTTCCAGCAACCAGTGATCTTTTTGGGAGCCGATGTCACTCATCCACCT
GCTGGTGATGGAAAGAAGCCTTCTATTGCTGCTGTTGTAGGTAGTATGGATGCACACCCAAGCAGATACTGTGCCACAGTAAGAGTTCAG
AGACCCCGACAGGAGATCATCCAGGACTTGGCCTCCATGGTCCGGGAACTTCTTATTCAATTTTATAAGTCAACTCGGTTCAAGCCTACT
CGTATCATCTTTTATCGGGATGGTGTTTCAGAGGGGCAGTTTAGGCAGGTATTATATTATGAACTACTAGCAATTCGAGAAGCCTGCATC
AGTTTGGAGAAAGACTATCAACCTGGAATAACCTACATTGTAGTTCAGAAGAGACATCACACTCGATTATTTTGTGCTGATAGGACAGAA
AGGGTTGGAAGAAGTGGCAATATCCCAGCTGGAACAACAGTTGATACAGACATTACACACCCATATGAGTTCGATTTTTACCTCTGTAGC
CATGCTGGAATACAGGGTACCAGTCGTCCTTCACACTATCATGTTTTATGGGATGATAACTGCTTTACTGCAGATGAACTTCAGCTGCTA
ACTTACCAGCTCTGCCACACTTACGTACGCTGTACACGATCTGTTTCTATACCTGCACCAGCGTATTATGCTCACCTGGTAGCATTTAGA
GCCAGATATCATCTTGTGGACAAAGAACATGACAGTGCTGAAGGAAGTCACGTTTCAGGACAAAGCAATGGGCGAGATCCACAAGCTCTT
GCCAAGGCTGTACAGATTCACCAAGATACCTTACGCACAATGTACTTCGCTTAAATAGTCCAAGTATATTCTCTGAGAGGAAGTACTGAA
AGATGAATTGACATACAACGTATGTTTCCAGTGAAGTCAATTGAGTAAGGACACCTCCAGCCATACAGAAACCAACACTGTGTGGGGGCC
AAGGTCTGATCCTTATGTTAATACAAGGAAGATTGTTTACTTCATCAAGGAACACAGCATCATTATGCAATATGAAACCAGCCAACTGCT
TTTTGTGCGGTCTCCTATAGGAAGTATCGCAATTGTTTTGTTTTCATTTCTTGTAGTCTAACCCTTTTAATGCCTTTACCTCAAGTTGCT
TGGCAGCACAACTATCTTTGCAAAAAAAAGTAAAGAAAAAGTAAATGATGGTTTAAAAAATACACACCTTCATGAATAATCAAAGTGATT
TTTCAGAATTATGTGTGCAAAAAATTAATGTGCATTCATATATTCTTGTAAAAGGTGTCTGTGTATTTTTAAAATATATACATCCATACT
TCATATGCATATATATCTAGATCTGGATTGATAATAGATATATATGTGTCTGTTATATATTTTAGAGTTCATTCCATTGGGGAATTTTCT
TTCCCTTTTATTCTACCCCCACTACCGCCTTTATTTCTCTATTTCCCTTGCCTTCATCACCTACATTTTTTTCCCAGTCCTACCAGTGAC
ATTCAAATGTTGATGTATCTGGTTCGTTTGAATATAAAATATGGCAAACTAGAATTCTACTTTTATTTTGCATACCCTACTCCTGACTCC
TATCTCATACACAATTCTGAGTTCTCAACTCTTGATATTGCTGTCTTAAGAAACAAAATTTTATATATATATGTATACATACATACACAG
ACACAGACACACACATATATATACATAAAATAACTTTCTGTGAGAGTGCGTCTCTCCCCTCCCACTCAGAACATACATTTACCATTTGCG
CAATTTGTATATAAGCAGTAGCAACCTGAACTATTCTTTTTCTTTTTTCTTTTTCTTTTCTTTCTTTTTTTTTTTTAATGAGACAGAGCC
TCGCTCTGTCACCAGGCTGGAGTGCAGTGGCGAGATCTCGGCTCACTGCAACTTCCGCCTCTCGGGTTCAAGCAATTCTCCTGCCTCAGC
CTCCCGAGTAGCTGGGTTTACAGGCATGTGCCACCACACCCAGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCGTGTTGGCCA
GGATGGTCTCGATCTCTTGACCTTGTGATCCACCCGCCTCGACCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCACCCGGCCTA
CTATTCTTTTTCTTTAGTGAGTTTGTTAAAGCTGCTATAAATATAAAACCTGTCAGAAGTTGTAACTTTCTCTCTGGTAAGTGATGTGTA
TTCTGAAGCCTTCTGTTTCTATGGGTTATACATGGAAATTCTTTAAAGGTTTTATAAAGGGTAAATATTTTAAAAGATTAGAGCTCTGTA
GGGTTGAGACCTCTGAAATTGAGTAGAGAGAAGAGTTTGTTGAGGGATTTTTTTGTTTTGTTTTTTGATAGTTTACTTGCTGCCTCTCAT
ACCTTAATGTGATTTTCATATATTTTTTATATATATATATGTATGTGTGTGTATATAAACACATATGTATGTGTTTGGAAGTATAGCTTC
CTTTTCTTTTATATTTATTAGAATAGTGCTTTAATAATTATAGAATTGTATTGGCAGCATCTTTTATAGAAATATAATCATGTTTATTTT
AAGAACTGACAACTTGTTTTTGCTATCTTTTAGTGCAATAAGCAGTTTTAAAGGAAAGTTGTGTCTGCATCTTTACCATGGATAGTAGGA
GGAACAGGCACCTCCATAGTTTAAAAGGGCAAAGAATACAGCCTTAATTTCAGAAGGAAAGTTTTGTAATTTTCAGTTTTAAAGCATATC
TTTTAAAATTCATCATGATAAAAGGCTGGACGCGGTGGCTCATGCCTGTAATCCTAGCACTTTGGGAGGCTGAGACAGGTATATCACCGG
AGCTCAGGAGTTTGAGACCAGCCTGGCCAACGTGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCTGGGCGTGGTAGTGGGCAC
CTCTAATCCCAGCTACTCGGGAGGCTGAGGCAGGATTGCTTGAACCTAGGAGGCGGAAGTTACAGTGAGCCAAGACTGCACCATTGCACT
CCAGCCTGGGCAACAAAACCAAAACTCCGTCTCAAAAGAAAAAAAAATCATAATGAAAATGAAGTGAAATTGCCTAAATGAGTCCAACTT
GAATATTAGAAATAAAGTTGAACTTTTATATAATTGTGAATAGCTTAACATATTTAAATTATTTGCAAATAGATTGTGTTTATTGAAGAA
TCATATTGGCTAGATGCCCATTTTCATTTACTAAAATGAATCAGGAAAATGCAAGATGATATTTTAAAACTTTTGCTAATGTATCACCAG
TATAACTTTCCTTTTAAAATTAAGGTGATAGTAACAAAGGAAGTTAGGACTTTGATCATTTTAAATCAGTTAAATCACTGAAACGTGGGA
AATTGTTTTACAAAACTTTTATTGATTACACTTTAAGGTATTAAAAAGTACTATAAAGCTATCAAAACTGAGTTTATCAGTAACATTGGA
TTCAGGGGAGCTTTGCACTTTGTAACTCATGAAAATTGCATTTTGATTTTTTTTTTTTTTGCACTGGTTCAGAGTATAGATACTACAGAT
TGTTTCCAGTGGGCATTGTTGTTAGCCTTTCAGAATTCCATCTGCACGTGAAACCTAATGGATTTAGATCTTTAGTTTCTCTCTTACCTG
TAATCCACTATTATTGCCAATTCACTGTATTTTGAGCCTAAAATCTGAGCCCATGTCCTCTGACAGGCATGAAATCTTTTGTCCCTCTGC
CAGAAAACTAAGAAAGTACTGTATTTTGTATGTTTATTATTTTGAAGTGTCTGAAATGCAATTTACAACACTGTTGCAAAGAACTTTACA
AAAGGTAATATTTGTATCGTATATACATTTTTTCTCCCAGCCTTCTCCCATCTCCTCCAGAAAAATTTCCTATAAAGATGGATTTTTTTA
CACTGAAATTTTACTGAATATAGTCAGGATCATGGGCAAGAGAAGAAAATAGTATACCCAAGATGATAAAAATTTAATTCGTCTATGCTT
GATCAGTGTGAGTAAAACATCTTCCTTTATCATGGGAGCTGCACAGATTCATGTGGGAAACTTTAGGGAATGACTGTAGATACCCTTTCT
CTATGTACTCTCTCACCTAATTTTCAGTCACTCATATATGCTAGAGTGGAGCCCTTAATTTAAATCTATTTGGAAGGACTTTTTTAAGAG
GAAAAATATTTTTTCTAAATTATAAAGCTTTACCTTTTGAGTGATTTCTTTTTTAGAGTGCTCTTACACTAGTCAGCATTGCTAGTTTAA
AGTTGATTAACTTGAAAGAGTATGTATACTATATTTCTATTTTGCTAACAAATTGGTATATTAATTACCATTGGTTCTTAATTACAAGAA
AACTTGTGCTTAGAATTTTAAGATAAAAGGCTAAGTGACAAATGCTTCTTGAAATTTGTCCTATTTATTGTTGCATTTCTGGTGTAGAAT
TTCTAATCTTTTTTATTTTAAAAAAGTTTTTTTTTTTAAGTTAAACATGAAATTCACAGTGACCCTTCTGCTCCTGCCCTTGCTCACTAA
CTATATCATGAATGCTAGATTTTGGTCTTCTTTTTTCTGTGATGTATCTTACGAGACTGACTGTAAAATATCAGTCTGGCAACTAGATAA
TTGATTTTCATATGAAGAAGAGTTGGGAGTTTAATGTATATTCTTGATGGTTAATGTGTCTACATAAAGTGCTGATACATGTATTATATC
ACAGTATCAGGTTACTGGCATGGAGGACCATACACTTACAATATTGTAGCTGCTATATTTATTTAAGTAGATTCTGACAGTTACTGCACT
AAACAGTAAGGAGATAAGCAGGATTCAAGGCTAGTGTTAGACCCTTTTTTTTCCTAAGAGTAAGGACACGGAATATCAAAGTAACAAAGG
GTGCTGCCATTTTAGTTTCAATTTAATATCAGGATATTCTTTGTTTTAGAAATGTAGATTTTGACTTTTACAGTTTGAAAAAGGGTACCT
CAGCCTCTTCAGTACTGGTTTTTTGGCACATTTCAACAGAAATATTAGATTCCCTTTCTTTTTCTTAATAGTGATCTTCTAACAAGTTTC
TTGGAAAAACTATCATTCTAAGGGAAATCCCTGTTTATAACCTATTAATATATTTCTATTCCTAGAAGAGAGTCTAGCAGGGATTCTAGT
AGGAATTACTGAGTGTTTTGGAAGGCACTTGATAGAGGCATCTCTGCTTTCCAGCACAGGGATTCTCAGCCTTCTAAAGATCTAGACCAG
TTTCCAAGCTAGCTTCTCCACAGCCCACCACTGCCTAGTGTTTGCTTGTGTATTCTCTAATGGATTTTAGGAGGATAGGCCTTCTGACAG
AGTCATGAAAGACTGAAGGCATGTCTAGGGAAATAAAACCTGACTTGCCCTTCAGCAGGAATGACTGGCAGCGGATCTCTGTGTTCAAGG
AAAGGGTGAGCGCTAAGCATGCCAGTGATGGATCCGAAGTATTTAGATGGATTGCAGACCAGGAATTAGAGACCGTTTGTGACTCAAGGA
ACTTGATGGATCTGTTTAGAGCCCTACATGAATTTGCCAAGGGCAGTGATTTTTATGAAATTCAAGAAGCAAACGACTTCGATACAGCTA
GAATATGTTGCAGTCTTCCTATTTCAAACTTGATTTTAATATTTTTACCAAGAAGTTTAACTGACAACTCTGCAAAATTTTCATTCAGTA
TCATTAAACCTGAGTTAAATGTTTGCTTAGCTTATCCTCTTAGATGTTCTTCTGTTGAACAGGCAGGTTGCCCTTAACAGTAACTTGCTA
CTTAAATTACCTTTTATTAGTTAGTCAAGCTGCAAAAATATCATTAGTGTGGCGTCTTTATTTTGGCTTTATCCATATGAAGTATTCATT
ATTTTCATTCTTTTTGAGAATTCATAAATGTCTTAAAGCTTCAGTAAGAATTGTTGGGAGGTTTGACATCAAGTAACGCCTTCCTGTGTA
GCAGTATAACCCTAATTTAGAACTCTTGTTTTCCTATTTCAGTCCTCATATTTGATCATAGAAAAGCACTTTTGTGATTCTATAGGAGTC
AAAAAATCAGCCAAGAGTAGGTAAGTCAGTCAGCACAGAAATCAGAAAGTGAGAATTTTCTCCAAAAAATCTTTTTAAAAAAGTCCTGCT
TATACTAAGAACATTCTTGATCCGTTGCAGTGTTAGAAATGACACTGTGATTAGTGAAAGCCAAGCTGAGTCCCAGGAAGCAGGGAGGGG
GAGTGTGTGTGTGTGTATATGTATGAGTGTGTATATATATAATCTCACACACACACACAAAGGGAAAAATTATTTTGACTTTTTTCCTAC
TTTTAAAATGGTACATTTAAGTTTATAATTTTCCATGTCAGTCAACATAATTTTTTAAACTAAGGTATAATGGTCAAGGCTTGTGCTAAT
ATTACCTACTACTCATTGAAATTTATATTACTTTACCCATCAAAACTAGTACTCCAGATGTTTACATCATTGATTAAATCTCAAGAATCT
TTTGTTCTTAAAATATGGAAGTTAAAGATTTTAATTTGAATTAAAGATAGAAGGATGGTAAATTCAATATAGAGGGTTGAGATTTACCAG
TGAGAAACCCTGTTGAAGTATCAGGTAAATGGTGTGACAAAATTAGAATCCTGTCAAATCACCTATCCAGCCATCGGGGTCCCTTCCTTT
TTTAGACTAATTTCTAAGGTAACCAGAATCTAATGTATCTATGTTAGGGTCTCAGTAAAGCAAAGACGTTTGTCAGGGCGTAGACTCTTG
AGTTAAATTTTTTAATCATTTTTTAAAGCAAGGCGGTTCTTAGAAAGTGCCTTTTCAGAAGATGGTGCTGTAGATTTTTATTTTTCAAGT
AGCACGAAGCTAAGAATTTTAAAGATAAATTATTTTAGAACTCCAAGAGTGTGACAGTTTCATAAAAATAATGTTAGTTGTTGTCTTGAA
TCTCGTCCAAGGGAACCAAGGAAAGCTTTTATGCAGTAAAGTATCTAGGTAAATGCTCACCAAATTTATTTTGTAAATTTGAAAACAAAA
TATTTAGTAGAATTACCTCTTTTAATTCCCAACTGTGTTGGAGGAAATCCATAATGCACATAAAACAGCAAACCTACTTAACTTTTTAAC
AAGATTATGGGTATAGTACCAATGTCCAAAGGGAAATGTAACTTGCCTGGAATCATAGGCAACATTTTCTAATTAATCTTTTTTTTTTTT
TTTTTTTTTGAGACAAAGTCTTGCTCTGTCACCTAGGCTGGAGTGCAGTGGCTCAATCTCAGCTTACTGCAAACTCCGCCTCCCGGGTTC
AAGTGATTCTCGTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCATGCACCACCACACCCGGCCCTAATTAGTCATTATTAAGGAGGA
CTGCTCATAAAGGCAGTACCAAATCATCATTCAGATCAGCTTAAGTGAGAAAGCAAAATGATAATCTCTATTGTTAGAGAAATTTTCTTT
TCTAGACACCAAGGAATATTTTAAATGATTTTTTATTTTTTCTAGGATGCAGGAACTATGAAAAATGATGACAAGGCATTTAAAAGGGTA
TGATCAGTTAAATAGAAGTAGGGTCTGCAAATTGTGCTTAAGGGGAAATAAGCAAAAGAAAGGAAAATAGTAGAACCTTTCATACTAATT
AGAAATGTAGTTACCTACCAGAGGGCAATTTTGCTCCATACCAGGAAGCAGTAAATAGCAGTAAATGATCACCTAGGCACTTCTTTCCTG
TGAATTTGGTGAGCATTCTTCCAGAAAAGAAGACTAAAAGCAAACAACAACAACAACAAAAAATACCACACCTCAGTAACCTTGTATGCT
GCATTATATAATAATGATAGTAAAATTATATTGTTTGGAGTGTACTGTGTCTGTTTGCAAATATACATGCACATTAAACTTTTTTGTTTT
TATAATGTCTTAATAGCAATTATGAGTTTATTTTTGTTAAGATTAATTTTTCTATTGTGATGTTTATATTTATTGGCAATTTGTATGCAA
CTTTTATATTTTGCTTGTCGGTTTTAAGGTATTTTATTTTTATAGATATTTCTAGCTTTCCTCATTCTTTGTAATAGCAGCAAAGATTAA
GATGGAGTGTTAATATACCAACCAAACTACGAATTCCATAAACTCTAGAGTTTGGATTTTTACCAATAAACCATTAACACTATTTTGTAA
CTTAGAATATTTAATGTTGTTTATATAGTGGGCATTAAAGACAGTCTTTAGACAGATTTCTACATGTGGAGGGGAGGTGGGGCTTTCCTG
TAAGTTTGATCCTTTTTTTCCCCTTTAGTAGCAAACTAACATAACAGATTGGATTTATTTTACCTGACTACAGTTTTGGGGAAACCTGTC
AAATAAATAATTGTTACATGCCTTTTTTTTTTAAATTTAAGCACATTGAAACTGCTTAAATGGTCACATTTTTCAGCATTAGGATTAAGA
TACCATTTTTGTAGGCCTGGAAAACAAATAGCAAATGATTCAAAATTCATTGAATTGACTTTGAAATGAAACTTTTCCCCCATAATTTGT
TATATGGAAGATTTGCTACCCTGATCTTTTCCCTAGCATACTTCTAAAGTTGATTGAATCCCTGAGTATCAATGAAGAAATCAGAGTTTA
AGTGGCTAGGGAGAGCCAGGTATAAAGACTGATTAATAGAGTACTTCAGCTAATTAAAAATTTAAATAGTAATAATTTATGAATGTGAAT
AAATTGGAAGGCAGCAAAAAGCATGATTATAGAATATTAAGTTCAATTATATATAGACAGTCCAGTTTCCTAGTGAATAGGTCAAGATTA
TTTGTTTTGTTTTGTGGCACTATCATAGTTCACTATAACTTCAAACTCCTGGGCTCAGGCTATCCTCCCACCTCAGCCTCTGAAGTAGCT
GGGACTACTCACATGCGCCACCATGCCCAGCTAATGGTTTTTTTCTTTAGAGATGGGGGTCACTATACTGCCCAGGCTGGTCTTGAACTC
CTAAGCTCAAGTGCTTCTCCCACATCAGCCTCCCAAAGTGCTGGGATTACAGCCATGAGCCACTGCATCTGGCCAAGATCAAGATTATGG
ATATTGGTATGTTAACTTTTAAAATAAAAGTACATGGGCTGGGCGCAGTGGCTAACGCCTGTAATCCCAGCAATTTGGGAGGCCGAGGCA
GGCAGACCACCTGAGGTCAGGGGTTCGTGACCAGCCTGGCCAACATGGCGAAACCCCGTCTCTACTAAACATACAAAAATTAGCTGGGCA
TGGTGGCACATGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCACTTGAACTCGGGAGGCGGAGGTTGCAGTGAGCCAAG
ATCGCGCCATTGCACTCCAGCCTGGGCAACAAGAGTGAAACTCCATCTCAGAAAATAAAAATAAAAATAAATAAAAGTACATGAAAAAAG
TATATTCCCTTAAGCAGGTAAAATACTTGCATTGTATTTTTACATCATGAATTTGCTTGTTAAGAAATTTCTTTTCTGTAAGTGGTTAAA
AGATAAACTGTATTCCATCCTCTGGGTTTTCAATTCTAAATTATTGGAGCTCAATGTATGACATTTTACTGTAGTGTATTCCACTGAGAG
GCAAGGAAATGGGAAAGTGTCAGGTAATTATAAATGGGAAAATTTTATTTTTATATGATGTAAAGTTTTACAGTTTAAAATAGATCAGCA
TGTGATTTCTTGTAGAGATTAGCCATTTCATTTCTTTTTGCATTTTTGCCAGTTACATTAGTTTGCCCTATGATATACTATTCTGAGATA
CTTCAGCCCCGCACACATCAAGTACTAATTGTATACAGATAGTACAGATTTGTACTCTGATTATAAGAATTTGTTACTACTAATTAAAAG
CAAATTAATGTGGCTGGGCGTGGTAGCTCACACCTGTAATCCCAGCACTTTGGGTGGGCGGCTGAGGCGGGCGGATCACGAGGTCAGGAG
TTGGAGACCAGCCTGCCCAATATGGTGAAACCCTGTCTCTACTAAAATTACAAAAATTAGCTGGGCTTGGCGGTACGTGCCTGTAATCCC
AGCTACTGGGAAGGCCGAGGCAGGAGAATGGCTTGAACCCAGGAGGCGGAGGTTGCAGTGAGCCAAGATCACACCACTGCACTCCAGCCT
GGGCGACAGAGCAAGACTCCGTCTCAAAAAAAAAAAAAGCAAAATATTTTTGCTGTGATTGTATGTCCCCTTTTAAGGATATTTATTGCG
CTTATAACCTTAATAGTTGTATTCATTACATTTCAACATGTCCAAGGTTAGCAGACATGTAGTTCCTGAAAACCAACATTTTAAAAGTTG
CCTCTGGGCTGGGCATGGTGGCTCACGCCTGTAATCCCTGCACTTTGGGAGGCCGAGGTGGGCGGATCACGAGGTCAAGAGATGGAGACC
ATCCTGGCCAACATGCTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCTGGGTGTGGTGGCACACGCCTGTAGTCCCAGCTACTTG
GGAGGCTGAGGCAGGAGAATCACTTGAACCTGGGAGGCGGAGGTTGCAGTGAGCCAAGATTGCACCGCTGCACTCCAGCCTGGCAACAGA
GCAAGACTCCATCTCAAAACAAACATACAAACAAAAAAAGGTGCCTCTGGTCCTGTGTTTTCTTTTTCCTTCTGAAAGTTCATAGAAACC
TGGCATATAGAGCTTATTTTGCTGTTTTAACTGGTTGGCTCCACAAATCCTGCTACCTGACATCAGTACAGCTTGACCGCAGTGAAGTAC
TTGATGGCTTGTTCATGTTTAGTTCACCTCTTTAGAAAGAAAGCTTTGTGGCCAGGTGCAGTGGCTCACACCTGTAATCCCAACACTTTG
GGCAGCTGAGGTGAGCAGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGCAAAACCCTGTCTCTTCTAAAAATACAAA
AATTAGCCGGGTGTGGTGGCGGAGGATGCAGTGAGCCAAGATCGTGCCACTGCACTCCAGCCTGGGCAACAGAGTGAGACTCTGTCTCAA
AAAAAAAAAAAAATCGTTGTGCAGTAATAGATCATCCCAAAAAAGAATTGCCATGAACAGCGTTATGCGTAGAAAACAGATGGAAGTGTT
GGTCATTAGAGCCTTGCTTTTTAAATTTTATTCTTTCCAAAAATTGGCGGTATGCTATCTATAATTTTATGTTTGATGTTGAAGAGGCAA
CACCAGAGACTAGAGAGGGAGATTACTCTGATATTTAGTGCCTAAAACTTTCATCTTGGCCGGGCACGGTGGCTCACACCTGTAATCCCA
GCACTTCGGGAGGCCGAGGCAGGCTGATTACCTGAGGTCAGGAGTTCGAGACCAGCCTGGACAACATGGCAAAACCCGTCTCTACTAAAA
ATACAAAAATTAGCCAGGCATGGTGGTGGGCGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCGAGAGAATCGTTTGAACCCGGTAGGC
GGAGGTTGCAGTGAGCCGAGATCATGCCACTGCACTCCAGCCTGGGCGACAAGAGTGAAACTCCGTCTCAAAAAATAATAATAATTTTAA
AAATAAAAGACAAAACTTTCATCTTTATTTCATGGCTTTATTTCATCTTTATTTCATTTTTGGTTGGGAAAACAAACAAAAATCTCTTAA
GTTAGTCCTTTAATAGTCTTTTTAGAACCAAAGAAGGAAAGACTGCAAAAATGTTGCATACGTGACTCTTTATTGTCAGAATCTGTAGAA
ACTGGAGGTCTTTGTAAAGAAATAGACTAGTAGGATTGTGAGAATATATAGTGAGGGGGGATTTAGGATAAGGCTTCCTTGCTGGGATCC
TTGGACAGAAACCTTACAATTGTTTAATATTTGCAGAGTAAAAGAGCAGCTATTGCTATTTGAACCTACAGAAGAGACCTAAGACGAGCG
TCTCTGTAATCTAAATTTATATGATAATGTTGTCCCAGACCCAAAGGCACACCTATTCTCAGTAACTTAGAGAAGTCTTGGAAGTTGCTT
CTGAATTACAGTAAAGAAATTAAATGAAGTCTTTATCCTTAAATAGGGCCAGGCATTGCTATCAACATAGTGTCTTTGGTTTTCCCCTTT
AAATAGAAAACACCAAGCAGGGCCTTTCCAGACAATGTAGTCTTTCCTGTAAAGAAAATGGTTTTGGTGTGGGATTTGGTAAAAACACTG
GTTAGTTTGTAATGAAGAAAGAATTTTGGCATAGACAGTCCGACCCAGTTCATGGATACAGTTTGATCCCAGGGAGTTTAACAAAAGGAA
GCTTTGGTTTTGCTAGCAACAGACTTGATCTTCTATAGTAATTAATTGCAATTAAGGTTTTCCAGGAGCTTTCTCATTTCTTAGCCCAGG
GTCCAACCCCATTCCCTCTTTAAAAAAGAAAGAATAGGCCGGGAGCAGTGGCTCATGCCTGCAATCCCAGCACTTTGGGAGGCCAAGGCA
GGTGGATCACAAGGTCAGGAGTTTGAGACCAGCGTGGCCAATATGGTGAAACCCTGTCTCTACTAAAAATACAAAATTAGCTAGGCGTGG
TGGCAGGCGCCTGAGGCTGAGGCAGGAGAATCCTGCTAGTCTGAATTACAATAAGGAAATTAAATGAAGGATTTATCTTTAATAGAGCCA
GGCATTGCTATCAACATAACATGTTTGGTTTTCCCCTTTAAATAGAAAACACCAAGCAGGGCCTTTCCAGACAAGGTAGTCTGGAACCCA
GGAGGCGGAGGTTGCAGTGAGCCGAGATCCCACCATTGCACTCCAGCCTGGGTGGCAGAGTGAGACTCCGTCTCAAAAAAAAAAAAAAGA
AGGAATAGGAAAAGGACTTAGAGGCAGTTGATATAGAATTCTACTGGGGGTAAATGACACTCTCAAAATACTTGGGAAAGAAGAATCACA
TGCCACAAGCTATAGCTTGATTAATATTTTAGCATGTTTTCCATGTTTGTATTCTAAAGTTTGTTTCCTTTGACATTCCATTATCTTACT
TACTAGAGTGCCACCATTCTTATTTGTAATACAATCAGTGTTTTATGCCATTTGTGAATCACACAATTGTTCTTTTTTCCCCATCACACA
CACTCACACACAAACACACACACTGTTAAAAATAAAAGAGGGGAAGGATAAAACAAAAATAGATAGAATGATGATTATTACAATGTAACT
TTAACATATATGAAGAGAAATTCTAACTCAGTTAAGTGAGAATTAAGATTGAAAGTATTAATGTTGCAAGTATTATCTCTAGCCATGGAA
TTTTTTGCTGGCTATAGAATGCTAATGTGAACAGAGTATATATCAGGAATATGATGTATTATGGCACAGTGATAATATTATTGTTGATAT
TAGCCAGATGTGGTGGTTTGCACCTGTAGTCCGAACTTCTCAGGAGGATGAGGCAGGAGGATAGTTGAGCCCAGGAGTTTAAAGCAAGCC
TGGGCAATACAGCAAGACCCCAATCTTTAAAATAAATAAATAAATAAGAATTATTCTTGAAAGTAATATTCTAACCTTCTGCCAACCAAC
AGAGATCCTCATATTCTTAAAGAAAATTAATATAGCTTATGGTTTTGATAAATTGGACTCTGATTTAAACTTTAAAATGTTATGACTTTT
ATTCTGATACATGGCTTCTAAAATATGTAAAAAATTATATTGAATGAATTAATACTTAACCTGTTCATTTCTCTTAATTTATGTATTTAT
TCTGACTTTATTATACAGCTTATGTCTCACATCTGCCTTCTTGATATGTGCAAAATATTGTGTAAAAATAGTTTAAAACTCATCCCAGTT
CCTAGTCAAGCGTGGGCTATAAGAGAGAAGGCTTAAGGTGTTCTTTAATGGAGGAACTTTTGAAAGATCACAAATGGAAAAAGCCTATTG
AGAATTTATTGCCTTTGAGAGTAGAAAGGGCTCTAGAATATGAGCCAGAGACTTGGAATTTAGTAATAGGTCTCCCACTGATTTGCTCCG
TGTCCTTAGGCAATTCGTTTAATCTCTGTGTGCCTAGTTTCCCCTTGTAAATAAGAGTGGTAATACCTGTCCTCACCTACCTCACTAAAT
TGTTGGAGTTCTTTTGTTCTGAGTCAGGGTCTCACTCTGTTGCCCAGGCTGAACTACAGTAGTGTGATCATAGCTCACTACAGCCTCCAA
CTCCTGGGCCCAAACTATCCTCCTGCTTCAGCCTCCCAAGTAGCTGGGACTAGAGGTACATGCCACCACACCCAGCTAATTATTTTCTTT
TATTGCAGAGATGGGGTCTCACATGTTGCCAAGGCTGATCTCTAACTCCTGAGCTCAAGCAGTCCTCCTGCCTCAGCCACCCAAAGTGCT
GGGATTATAGGCATGATCACTAAATTGTTGTAAGAATAAGATAATGTTTGCGGAAGCATTTGAGTTCTCCAAAGGAAAAGCTATTCAGAC
GTTCAAGATAATAGAAGAGTGTTGTGTGAAGGATTCCTTTCCAGTTTGCCTCTGTGAAAATGTCTTTGTTGTAGATCATTTTATGAAATA
GGAATAAGAGAAACATAGGCCTTATCATGGTGTAGTGTTCACTTACAAACATATCCTGTTGTTTCTTCCCTGCAAGATATCCAGCACACA
GGCTGAATTTTTCTTTATAATAATCCTTGGCAAAAGCATAACTTTTCAAAAACCAAATGATTTTAGTGGTGCTATGGCAGCTGCAGTTTT
GAGTTAGATTAATGTGGTGAAAACCATCAAATACTTAGAAATTGACTGGGTGCGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGC
CGAGGTAGGTGGATCACTTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGCAAAACCCCGTCTCTACTAAAGATACAAAAATTAG
CTGGGCACGATGGAGGGTGCCTGTAATCCCAGCTACTCGGGAGGCTAAGGTGGGAGAATTGCTTGGACCCAGGTGGCAGAGGTTGCAGTG
AGCCAAGATTGTGCCACTGCACTCCAGCCTGGGCAACAAAGCGAAGCTCTGTCTCAATAAAAAAAAAAATAATAATAATAAAATACAAAT
ACTTAGAAATTAACTTCGCCTTTGCCTTCAGGCACTTTTGCTACATGTTAGCATCAGAGGCTATTGTACAACTAGATGGTTATTCCCTGT
TTCTTGGCCGATTTTTGGTACCTTTCTTTGAAGAAGAGGGTTAGATTTTAAGAAAGAAAGTGTGCTTATTTCACTCATGTCTTTGCAGAA
TTTAACTTTGCTTTACTTTAAAAATTCCAATCATCATGTACCTATAAAGGTTAAAATATAGTGAAAGTTTCTGCTTCATGTGAATTCAAT
TCTGAGCACCTGCAGGTCATATCAGGTGTCTGATGCAGTTACCTTTATAGATCGTGGCAGGTCCTTACATTTCAACAGGCTTATGCATTT
CCATGGGGGGAAGAGATTCTGTTTCTAGGAAATTACAAAGGGCACACCACTGCAGGGAGTGTAAACAATTCTTTGTTGCAACAGACAAGA
TTTTTTTTAAAAAAAGAAAAAAGGATGCATTTTAGGTACACAGGGTATGGACGCATTCAACATTTACTTTTATCTCCACAGATGCCAACC
TCCCCTTGTTGCAGGCAGTTGGGCTTTTCCAACTCATTGCTAACAAAGCTGGCATCTGCATTAATTTCAATGAGAATTTCAAGTACTGAA
GATGAAAAGTTGGGGAGATTCATGTTTGAAAAATGAAAAATGAACAAAAAATCCACCTTGTGCAGTGAGATAGCTAACGCTGATATATCA
GGAATAATTTTAAACTATTTTTGCTGTAATGTGTAGCTTTAATGTCTCTTTTCAGTTATGGACCCATAAAAGTATTCCTATATCTTGTGA
ATAAAGATCATTCTTGTGGACTAGTACGTGGATGCATTCATAGGCTTTGGGAAGCAGTGGTGTGCGTATGTGTGTCTATATCAATATTTT
ATGTTTATAACTCTGCGTATTAAGTTTATATAGAAAAAAATAATGTCTTTCTTTAGTGTTTGGGGGACTCAATGGTAATATGACCATTGC
AGTGTAATCTGACTGCTCACTCTAGAGAACACTTCTGTTATACACAATGCACATACAAACATACACCCCTAAAGCGTAGCTAACTGCTCC
CACTAGATAATTGCTGCTAAAAACAAAACAAAACAAAACAATACAAAACAAAAAAAACCCTAAGTAATGGAGGAAGAAATAGCATTCTTT
TAAAAGGGGCTTTTCTGAAGAGTAAAATGTAAATACAGGACATGTGGGGAGGGTGGGGCCGCCTGCAAAATGTCCTGAAGATGGACAAAT
AGCCTTTTAAATTCTACTTTTTAACCATCTTTACCGTGTGTGCCTATTTGTATTGCAGATGTGAACTACTATTTTTGGAGGTTGATATCA
GTATGTTTTGAAACTGAATTATTACATAAAATCAGAGTAACCTCTTTCTCCATCCTCCTTTTCCACACTATTCTTGCCAAATATTTCTAC
TGAAACCCAGTTTCAGCAAGGCAAAATGATGGGACTCTCAAACCTCCCTCCTCATCTTCCCTTCCCCTCTGTCTTATGCCTGGCCTGGCC
TTTTTTGTTGTTGTTGGCTTTTCATAAGTAAGAAAAATTTATTGTAGTATTTCAAGACTGCAGAATTTCAAGTGTATATCTATAAATCTT
TTTTTAAAATCTTCGGCTACACAGTAACATCAATTAAAACAGAAGAGTGAGTCTAAGTCTGTAATATGCTGTAGGACCAGATAAGATTTT
GAATGAGACTAAACTTGACTGCCATATTTTAAGAGGAAATTGAAACTTTATGGTGGAGAATGGATGAGAGCAAGTCTATGATATATATGT
AGTCATTGTATAATTAGAAACACCAAATGCTGAATCCTATCACTGTGTTCTTGGGGGCCAGGCCTTGGATTTGGTTGTCATTTAAACTCC
TTGAAGATTATATGTAATTATAATGAGCAGAAGGCAAATAAAGTTTTTGAACAAAAGTCCTTGTTTTCAGTATTTAAAATTTGGTAATAT
ATTTTCTTTTTCAGTTAAACTATCTTCCCCACAAAAAATATTATACTTCAGTTAAACTATCTTCCCCACAGAAATTATTATACTACGAAC
AAGTTATGAGTGAGACTGAGAAGCTTGAAGAAGCTGGTTTTTAAGCAGCTCATATAATATTTTGTGTTAAAGAAAGTGTCATTGTTTCCT
GTTGGGAGGCAAATAACAACAACAACAAAAGAAATTGTCATGATTCTTTCTGAGCCAAACTGTCACGAAATGTTCTGTGACAGAACCACT
ACTCTTTTTTCTGCCATTCTGCCTACTGGAGAGTTCTATGTTGTATTTGTTTTTAATCCTTGATTTTAAAAATATTAATGGTTTTAGTGT

>In-frame_ARHGEF2_ENST00000313667_chr1_155927504_-_AGO3_ENST00000397828_chr1_36432556_+_2580nt
ATGTCTCGGATCGAATCCCTCACGCGGGCGCGGATCGACCGGAGCAGAGAGCTGGCGAGCAAGACCCGGGAAAAGGAGAAGATGAAGGAA
GCCAAGGATGCCCGCTATACCAATGGGCACCTCTTCACCACCATTTCAGTTTCAGGCATGACCATGTGCTATGCCTGTAACAAGAGCATC
ACAGCCAAGGAAGCCCTCATCTGCCCAACCTGCAATGTGACTATCCACAACCGCTGTAAAGACACCCTCGCCAACTGTACCAAGGTCAAG
CAGAAGCAACAGAAAGCGGCCCTGCTGAAGAACAACACCGCCTTGCAGTCCGTTTCTCTTCGAAGTAAGACAACCATCCGGGAGCGGCCA
AGCTCGGCCATCTACCCCTCCGACAGCTTCCGGCAGTCCCTCCTGGGCTCCCGCCGTGGCCGCTCCTCCTTGTCTTTAGCCAAGAGTGTT
TCTACCACCAACATTGCTGGACATTTCAATGATGAGTCTCCCCTGGGGCTGCGCCGGATCCTCTCACAGTCCACAGACTCCCTCAACATG
CGGAACCGAACCCTATCCGTGGAATCCCTCATTGACGAAGAGGTAATCTACAGTGAGCTGATGAGTGACTTTGAGATGGATGAGAAGGAC
TTTGCAGCTGACTCTTGGAGTCTTGCTGTGGACAGCAGCTTCCTGCAGCAGCATAAAAAGGAGGTGATGAAGCAGCAAGATGTCATCTAT
GAGCTAATCCAGACAGAGCTGCACCATGTGAGGACACTGAAGATCATGACCCGCCTCTTCCGCACGGGGATGCTGGAAGAGCTACACTTG
GAGCCAGGAGTGGTCCAGGGCCTGTTCCCCTGCGTGGACGAGCTCAGTGACATCCATACACGCTTCCTCAGCCAGCTATTAGAACGCCGA
CGCCAGGCCCTGTGCCCTGGCAGCACCCGGAACTTTGTCATCCATCGCTTGGGTGATCTGCTCATCAGCCAGTTCTCAGGTCCTAGTGCG
GAGCAGATGTGTAAGACCTACTCGGAGTTCTGCAGCCGCCACAGCAAGGCCTTAAAGCTCTATAAGGAGCTGTACGCCCGAGACAAACGC
TTCCAGCAATTCATCCGGAAAGTGACCCGCCCCGCCGTGCTCAAGCGGCACGGGGTACAGGAGTGCATCCTGCTGGTGACTCAGCGCATC
ACCAAGTACCCGTTACTCATCAGCCGCATCCTGCAGCATTCCCACGGGATCGAGGAGGAGCGCCAGGACCTGACCACAGCACTGGGGCTA
GTGAAGGAGCTGCTGTCCAATGTGGACGAGGGTATTTATCAGCTGGAGAAAGGGGCCCGTCTGCAGGAGATCTACAACCGCATGGACCCT
CGGGCCCAAACCCCAGTGCCTGGCAAGGGCCCCTTTGGCCGAGAGGAACTTCTGAGGCGCAAACTCATCCACGATGGCTGCCTGCTCTGG
AAGACAGCGACGGGGCGCTTCAAAGATGTGCTAGTGCTGCTGATGACAGATGTACTGGTGTTTCTCCAGGAAAAGGACCAGAAGTACATC
TTTCCTACCCTGGACAAGCCTTCAGTGGTATCGCTGCAGAATCTAATCGTACGAGACATTGCCAACCAGGAGAAAGGGATGTTTCTGATC
AGCGCAGCCCCACCTGAGATGTACGAGGTGCACACAGCATCCCGGGATGACCGGAGCACCTGGATCCGGGTCATTCAGCAGAGCGTGCGC
ACGGAGGTGGTTGACTCAATGGTTCAGCATTTTAAAGTAACTATATTTGGAGACCGTAGACCAGTTTATGATGGAAAAAGAAGTCTTTAC
ACCGCCAATCCACTTCCTGTGGCAACTACAGGGGTAGATTTAGACGTTACTTTACCTGGGGAAGGTGGAAAAGATCGACCTTTCAAGGTG
TCAATCAAATTTGTCTCTCGGGTGAGTTGGCACCTACTGCATGAAGTACTGACAGGACGGACCTTGCCTGAGCCACTGGAATTAGACAAG
CCAATCAGCACTAACCCTGTCCATGCCGTTGATGTGGTGCTACGACATCTGCCCTCCATGAAATACACACCTGTGGGGCGTTCATTTTTC
TCCGCTCCAGAAGGATATGACCACCCTCTGGGAGGGGGCAGGGAAGTGTGGTTTGGATTCCATCAGTCTGTTCGGCCTGCCATGTGGAAA
ATGATGCTTAATATCGATGAAAGAGACCTCTGGCAGCAGTGTGGAGAATAGATAGAGGAGAAAAAACTAATCTGAGAAGCCAGTTAGGAG
GCTTTTCAATCACTAGTTCAGGTTTCAGTCTACATGTTACTTCCTTGAGAAGCAGTGTTTGACACCCTTCTCCCCCAATCCAGCCATCCC
CCAAGTCTGAGTTAGGTATTTCTCTTCTGTATTCCCATAGCACAGTGTAATTCCCCTATAATAGCATGTATCACCTTGAATTATGGGTGT
TTATTGTTCTGTCTCTCCTGTTAGAACGAAAGCTCCATGAAGGGATTGTCATTTTATTCACCAGTGTACCCTCTATGCCCAGCACAACTT


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FusionGenePPI for ARHGEF2_AGO3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
ARHGEF2MYC, PAK1, YWHAQ, RAC1, RHOA, PLCG1, MARK2, TAF10, MAPK1, YWHAG, MARK4, YWHAH, ELAVL1, USP21, YWHAZ, NOTCH1, VCP, PEX14, MMS19, FBXO6, ANKRD28, PPP6C, PPP6R1, YWHAB, RPA3, RPA2, RPA1, CEP250, RPP25L, MOV10, NXF1, CCDC8, EGFR, WDR83, FGL1, NTRK1, COPS7A, KLC2, PRDX1, PSME3, CEP170, CNTRL, SCLT1, DCTN1, PPP2R1A, FOXO3, SNW1, CDC5L, PPP2CA, PPP2CB, PAK7, UBE2AAGO3DICER1, UBC, FLNA, PRMT5, SF3B6, SPTBN1, SPTAN1, OTUD4, MYH9, TNRC6B, EIF4B, IPO8, AGO2, HSP90AB1, HSPA9, SUN2, PSPC1, CCT3, EIF3L, ATAD3B, TAB1, PRPF31, TUBA1A, STK38, TUBB4A, TUBB4B, TUBB2A, TUBB, TRIM21, EEF1A1, DBT, RUVBL2, WDR77, DNAJA1, DDOST, QPCTL, CLNS1A, PHB2, SPIN1, AGO4, CUL3, CUL5, CAND1, TNRC6A, TNRC6C, ATP4B, SLC22A2, BDNF, ATP6V0D2, AGO1, PRKAR1A, TARBP2, ZNF346, HSP90AA1, HSP90AB4P, HSP90AB3P, HSP90AA5P, AP3M1, AP3D1, FKBP5, AP3B1, AP3S1, ANKMY2, LONRF3, RANGRF, XPO1, BAG5, CIR1, ATOH1, BRCA1


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
HgeneARHGEF2chr1:155927504chr1:36432556ENST00000313667-1322131_161570986DYNLT1
HgeneARHGEF2chr1:155927504chr1:36432556ENST00000313695-1322131_161543959DYNLT1
HgeneARHGEF2chr1:155927504chr1:36432556ENST00000361247-1322131_161571987DYNLT1
HgeneARHGEF2chr1:155927504chr1:36432556ENST00000368316-1726131_161543959DYNLT1
TgeneAGO3chr1:155927504chr1:36432556ENST00000246314+017530_567-205627guide RNA
TgeneAGO3chr1:155927504chr1:36432556ENST00000246314+017758_805-205627guide RNA
TgeneAGO3chr1:155927504chr1:36432556ENST00000373191+119530_56763861guide RNA
TgeneAGO3chr1:155927504chr1:36432556ENST00000373191+119758_80563861guide RNA


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for ARHGEF2_AGO3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for ARHGEF2_AGO3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource