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Fusion gene ID: 2554 |
FusionGeneSummary for ARHGEF25_NTRK1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ARHGEF25_NTRK1 | Fusion gene ID: 2554 | Hgene | Tgene | Gene symbol | ARHGEF25 | NTRK1 | Gene ID | 115557 | 4914 |
| Gene name | Rho guanine nucleotide exchange factor 25 | neurotrophic receptor tyrosine kinase 1 | |
| Synonyms | GEFT|p63RhoGEF | MTC|TRK|TRK1|TRKA|Trk-A|p140-TrkA | |
| Cytomap | 12q13.3 | 1q23.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | rho guanine nucleotide exchange factor 25RAC/CDC42 exchange factorRho guanine nucleotide exchange factor (GEF) 25RhoA/RAC/CDC42 exchange factorguanine nucleotide exchange factor GEFTrac/Cdc42/Rho exchange factor GEFTrhoA/Rac/Cdc42 guanine nucleotide | high affinity nerve growth factor receptorOncogene TRKTRK1-transforming tyrosine kinase proteingp140trkneurotrophic tyrosine kinase, receptor, type 1tropomyosin-related kinase Atyrosine kinase receptor A | |
| Modification date | 20180526 | 20180523 | |
| UniProtAcc | Q86VW2 | P04629 | |
| Ensembl transtripts involved in fusion gene | ENST00000333972, ENST00000286494, ENST00000477314, | ENST00000392302, ENST00000368196, ENST00000524377, ENST00000358660, ENST00000531606, | |
| Fusion gene scores | * DoF score | 3 X 3 X 2=18 | 15 X 12 X 8=1440 |
| # samples | 3 | 23 | |
| ** MAII score | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(23/1440*10)=-2.6463630453853 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: ARHGEF25 [Title/Abstract] AND NTRK1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Oncogene involved fusion gene, in-frame and retained their domain. Kinase involved fusion gene, inframe and retained kinase domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | NTRK1 | GO:0006468 | protein phosphorylation | 15488758 |
| Tgene | NTRK1 | GO:0008285 | negative regulation of cell proliferation | 15488758 |
| Tgene | NTRK1 | GO:0010976 | positive regulation of neuron projection development | 15488758 |
| Tgene | NTRK1 | GO:0018108 | peptidyl-tyrosine phosphorylation | 2927393 |
| Tgene | NTRK1 | GO:0043547 | positive regulation of GTPase activity | 15488758 |
| Tgene | NTRK1 | GO:0046579 | positive regulation of Ras protein signal transduction | 15488758 |
| Tgene | NTRK1 | GO:0046777 | protein autophosphorylation | 15488758 |
| Tgene | NTRK1 | GO:0048011 | neurotrophin TRK receptor signaling pathway | 15488758 |
| Tgene | NTRK1 | GO:0051092 | positive regulation of NF-kappaB transcription factor activity | 15488758 |
| Tgene | NTRK1 | GO:0070374 | positive regulation of ERK1 and ERK2 cascade | 15488758 |
| Tgene | NTRK1 | GO:1904646 | cellular response to amyloid-beta | 11927634 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | SARC | TCGA-DX-A7EI-01A | ARHGEF25 | chr12 | 58008800 | + | NTRK1 | chr1 | 156841415 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000333972 | ENST00000392302 | ARHGEF25 | chr12 | 58008800 | + | NTRK1 | chr1 | 156841415 | + |
| In-frame | ENST00000333972 | ENST00000368196 | ARHGEF25 | chr12 | 58008800 | + | NTRK1 | chr1 | 156841415 | + |
| In-frame | ENST00000333972 | ENST00000524377 | ARHGEF25 | chr12 | 58008800 | + | NTRK1 | chr1 | 156841415 | + |
| In-frame | ENST00000333972 | ENST00000358660 | ARHGEF25 | chr12 | 58008800 | + | NTRK1 | chr1 | 156841415 | + |
| 5CDS-intron | ENST00000333972 | ENST00000531606 | ARHGEF25 | chr12 | 58008800 | + | NTRK1 | chr1 | 156841415 | + |
| In-frame | ENST00000286494 | ENST00000392302 | ARHGEF25 | chr12 | 58008800 | + | NTRK1 | chr1 | 156841415 | + |
| In-frame | ENST00000286494 | ENST00000368196 | ARHGEF25 | chr12 | 58008800 | + | NTRK1 | chr1 | 156841415 | + |
| In-frame | ENST00000286494 | ENST00000524377 | ARHGEF25 | chr12 | 58008800 | + | NTRK1 | chr1 | 156841415 | + |
| In-frame | ENST00000286494 | ENST00000358660 | ARHGEF25 | chr12 | 58008800 | + | NTRK1 | chr1 | 156841415 | + |
| 5CDS-intron | ENST00000286494 | ENST00000531606 | ARHGEF25 | chr12 | 58008800 | + | NTRK1 | chr1 | 156841415 | + |
| intron-3CDS | ENST00000477314 | ENST00000392302 | ARHGEF25 | chr12 | 58008800 | + | NTRK1 | chr1 | 156841415 | + |
| intron-3CDS | ENST00000477314 | ENST00000368196 | ARHGEF25 | chr12 | 58008800 | + | NTRK1 | chr1 | 156841415 | + |
| intron-3CDS | ENST00000477314 | ENST00000524377 | ARHGEF25 | chr12 | 58008800 | + | NTRK1 | chr1 | 156841415 | + |
| intron-3CDS | ENST00000477314 | ENST00000358660 | ARHGEF25 | chr12 | 58008800 | + | NTRK1 | chr1 | 156841415 | + |
| intron-intron | ENST00000477314 | ENST00000531606 | ARHGEF25 | chr12 | 58008800 | + | NTRK1 | chr1 | 156841415 | + |
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FusionProtFeatures for ARHGEF25_NTRK1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ARHGEF25 | NTRK1 |
| May play a role in actin cytoskeleton reorganization indifferent tissues since its activation induces formation of actinstress fibers. It works as a guanine nucleotide exchange factorfor Rho family of small GTPases. Links specifically G alpha q/11-coupled receptors to RHOA activation. May be an importantregulator of processes involved in axon and dendrite formation. Inneurons seems to be an exchange factor primarily for RAC1.Involved in skeletal myogenesis (By similarity). {ECO:0000250,ECO:0000269|PubMed:11861769, ECO:0000269|PubMed:12547822,ECO:0000269|PubMed:15069594, ECO:0000269|PubMed:15632174,ECO:0000269|PubMed:16314529, ECO:0000269|PubMed:17606614}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | ARHGEF25 | chr12:58008800 | chr1:156841415 | ENST00000333972 | + | 11 | 16 | 160_336 | 359 | 620 | Domain | DH |
| Hgene | ARHGEF25 | chr12:58008800 | chr1:156841415 | ENST00000286494 | + | 10 | 15 | 278_299 | 320 | 581 | Region | Note=Important for binding to Rho GTPases |
| Hgene | ARHGEF25 | chr12:58008800 | chr1:156841415 | ENST00000333972 | + | 11 | 16 | 278_299 | 359 | 620 | Region | Note=Important for binding to Rho GTPases |
| Tgene | >NTRK1 | chr12:58008800 | chr1:156841415 | ENST00000368196 | + | 5 | 16 | 299_365 | 239 | 791 | Domain | Ig-like C2-type 2 |
| Tgene | >NTRK1 | chr12:58008800 | chr1:156841415 | ENST00000368196 | + | 5 | 16 | 510_781 | 239 | 791 | Domain | Protein kinase |
| Tgene | >NTRK1 | chr12:58008800 | chr1:156841415 | ENST00000392302 | + | 6 | 17 | 299_365 | 209 | 761 | Domain | Ig-like C2-type 2 |
| Tgene | >NTRK1 | chr12:58008800 | chr1:156841415 | ENST00000392302 | + | 6 | 17 | 510_781 | 209 | 761 | Domain | Protein kinase |
| Tgene | >NTRK1 | chr12:58008800 | chr1:156841415 | ENST00000524377 | + | 5 | 17 | 299_365 | 239 | 797 | Domain | Ig-like C2-type 2 |
| Tgene | >NTRK1 | chr12:58008800 | chr1:156841415 | ENST00000524377 | + | 5 | 17 | 510_781 | 239 | 797 | Domain | Protein kinase |
| Tgene | >NTRK1 | chr12:58008800 | chr1:156841415 | ENST00000368196 | + | 5 | 16 | 516_524 | 239 | 791 | Nucleotide binding | ATP |
| Tgene | >NTRK1 | chr12:58008800 | chr1:156841415 | ENST00000392302 | + | 6 | 17 | 516_524 | 209 | 761 | Nucleotide binding | ATP |
| Tgene | >NTRK1 | chr12:58008800 | chr1:156841415 | ENST00000524377 | + | 5 | 17 | 516_524 | 239 | 797 | Nucleotide binding | ATP |
| Tgene | >NTRK1 | chr12:58008800 | chr1:156841415 | ENST00000368196 | + | 5 | 16 | 440_796 | 239 | 791 | Topological domain | Cytoplasmic |
| Tgene | >NTRK1 | chr12:58008800 | chr1:156841415 | ENST00000392302 | + | 6 | 17 | 440_796 | 209 | 761 | Topological domain | Cytoplasmic |
| Tgene | >NTRK1 | chr12:58008800 | chr1:156841415 | ENST00000524377 | + | 5 | 17 | 440_796 | 239 | 797 | Topological domain | Cytoplasmic |
| Tgene | >NTRK1 | chr12:58008800 | chr1:156841415 | ENST00000368196 | + | 5 | 16 | 424_439 | 239 | 791 | Transmembrane | Helical |
| Tgene | >NTRK1 | chr12:58008800 | chr1:156841415 | ENST00000392302 | + | 6 | 17 | 424_439 | 209 | 761 | Transmembrane | Helical |
| Tgene | >NTRK1 | chr12:58008800 | chr1:156841415 | ENST00000524377 | + | 5 | 17 | 424_439 | 239 | 797 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >ARHGEF25 | chr12:58008800 | chr1:156841415 | ENST00000286494 | + | 10 | 15 | 160_336 | 320 | 581 | Domain | DH |
| Hgene | >ARHGEF25 | chr12:58008800 | chr1:156841415 | ENST00000286494 | + | 10 | 15 | 348_466 | 320 | 581 | Domain | PH |
| Hgene | >ARHGEF25 | chr12:58008800 | chr1:156841415 | ENST00000333972 | + | 11 | 16 | 348_466 | 359 | 620 | Domain | PH |
| Hgene | >ARHGEF25 | chr12:58008800 | chr1:156841415 | ENST00000286494 | + | 10 | 15 | 467_493 | 320 | 581 | Region | Note=Sufficient to bind activated GNAQ |
| Hgene | >ARHGEF25 | chr12:58008800 | chr1:156841415 | ENST00000333972 | + | 11 | 16 | 467_493 | 359 | 620 | Region | Note=Sufficient to bind activated GNAQ |
| Tgene | NTRK1 | chr12:58008800 | chr1:156841415 | ENST00000368196 | + | 5 | 16 | 148_193 | 239 | 791 | Domain | Note=LRRCT |
| Tgene | NTRK1 | chr12:58008800 | chr1:156841415 | ENST00000368196 | + | 5 | 16 | 194_283 | 239 | 791 | Domain | Ig-like C2-type 1 |
| Tgene | NTRK1 | chr12:58008800 | chr1:156841415 | ENST00000392302 | + | 6 | 17 | 148_193 | 209 | 761 | Domain | Note=LRRCT |
| Tgene | NTRK1 | chr12:58008800 | chr1:156841415 | ENST00000392302 | + | 6 | 17 | 194_283 | 209 | 761 | Domain | Ig-like C2-type 1 |
| Tgene | NTRK1 | chr12:58008800 | chr1:156841415 | ENST00000524377 | + | 5 | 17 | 148_193 | 239 | 797 | Domain | Note=LRRCT |
| Tgene | NTRK1 | chr12:58008800 | chr1:156841415 | ENST00000524377 | + | 5 | 17 | 194_283 | 239 | 797 | Domain | Ig-like C2-type 1 |
| Tgene | NTRK1 | chr12:58008800 | chr1:156841415 | ENST00000368196 | + | 5 | 16 | 116_137 | 239 | 791 | Repeat | Note=LRR 2 |
| Tgene | NTRK1 | chr12:58008800 | chr1:156841415 | ENST00000368196 | + | 5 | 16 | 90_113 | 239 | 791 | Repeat | Note=LRR 1 |
| Tgene | NTRK1 | chr12:58008800 | chr1:156841415 | ENST00000392302 | + | 6 | 17 | 116_137 | 209 | 761 | Repeat | Note=LRR 2 |
| Tgene | NTRK1 | chr12:58008800 | chr1:156841415 | ENST00000392302 | + | 6 | 17 | 90_113 | 209 | 761 | Repeat | Note=LRR 1 |
| Tgene | NTRK1 | chr12:58008800 | chr1:156841415 | ENST00000524377 | + | 5 | 17 | 116_137 | 239 | 797 | Repeat | Note=LRR 2 |
| Tgene | NTRK1 | chr12:58008800 | chr1:156841415 | ENST00000524377 | + | 5 | 17 | 90_113 | 239 | 797 | Repeat | Note=LRR 1 |
| Tgene | NTRK1 | chr12:58008800 | chr1:156841415 | ENST00000368196 | + | 5 | 16 | 33_423 | 239 | 791 | Topological domain | Extracellular |
| Tgene | NTRK1 | chr12:58008800 | chr1:156841415 | ENST00000392302 | + | 6 | 17 | 33_423 | 209 | 761 | Topological domain | Extracellular |
| Tgene | NTRK1 | chr12:58008800 | chr1:156841415 | ENST00000524377 | + | 5 | 17 | 33_423 | 239 | 797 | Topological domain | Extracellular |
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FusionGeneSequence for ARHGEF25_NTRK1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_ARHGEF25_ENST00000333972_chr12_58008800_+_NTRK1_ENST00000392302_chr1_156841415_+_911aa MKPPDRPAPGRTDRILGVMGGMLRACALPGQEGPPRRSPLGLVGTEPESERTEGDHRRDREHEVLAGALQPESYSIAGSEGSISASAASG LAAPSGPSSGLSSGPCSPGPPGPVSGLRRWLDHSKHCLSVETEADSGQAGPYENWMLEPALATGEELPELTLLTTLLEGPGDKTQPPEEE TLSQAPESEEEQKKKALERSMYVLSELVETEKMYVDDLGQIVEGYMATMAAQGVPESLRGRDRIVFGNIQQIYEWHRDYFLQELQRCLKD PDWLAQLFIKHERRLHMYVVYCQNKPKSEHVVSEFGDSYFEELRQQLGHRLQLNDLLIKPVQRIMKYQLLLKDFLKYYNRAGMDTADLEK SGGLPSLGLTLANVTSDLNRKNVTCWAENDVGRAEVSVQVNVSFPASVQLHTAVEMHHWCIPFSVDGQPAPSLRWLFNGSVLNETSFIFT EFLEPAANETVRHGCLRLNQPTHVNNGNYTLLAANPFGQASASIMAAFMDNPFEFNPEDPIPDTNSTSGDPVEKKDETPFGVSVAVGLAV FACLFLSTLLLVLNKCGRRNKFGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWEL GEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGP DAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPP ESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQ >In-frame_ARHGEF25_ENST00000333972_chr12_58008800_+_NTRK1_ENST00000368196_chr1_156841415_+_911aa MKPPDRPAPGRTDRILGVMGGMLRACALPGQEGPPRRSPLGLVGTEPESERTEGDHRRDREHEVLAGALQPESYSIAGSEGSISASAASG LAAPSGPSSGLSSGPCSPGPPGPVSGLRRWLDHSKHCLSVETEADSGQAGPYENWMLEPALATGEELPELTLLTTLLEGPGDKTQPPEEE TLSQAPESEEEQKKKALERSMYVLSELVETEKMYVDDLGQIVEGYMATMAAQGVPESLRGRDRIVFGNIQQIYEWHRDYFLQELQRCLKD PDWLAQLFIKHERRLHMYVVYCQNKPKSEHVVSEFGDSYFEELRQQLGHRLQLNDLLIKPVQRIMKYQLLLKDFLKYYNRAGMDTADLEK SGGLPSLGLTLANVTSDLNRKNVTCWAENDVGRAEVSVQVNVSFPASVQLHTAVEMHHWCIPFSVDGQPAPSLRWLFNGSVLNETSFIFT EFLEPAANETVRHGCLRLNQPTHVNNGNYTLLAANPFGQASASIMAAFMDNPFEFNPEDPIPDTNSTSGDPVEKKDETPFGVSVAVGLAV FACLFLSTLLLVLNKCGRRNKFGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWEL GEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGP DAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPP ESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQALAQ >In-frame_ARHGEF25_ENST00000333972_chr12_58008800_+_NTRK1_ENST00000524377_chr1_156841415_+_917aa MKPPDRPAPGRTDRILGVMGGMLRACALPGQEGPPRRSPLGLVGTEPESERTEGDHRRDREHEVLAGALQPESYSIAGSEGSISASAASG LAAPSGPSSGLSSGPCSPGPPGPVSGLRRWLDHSKHCLSVETEADSGQAGPYENWMLEPALATGEELPELTLLTTLLEGPGDKTQPPEEE TLSQAPESEEEQKKKALERSMYVLSELVETEKMYVDDLGQIVEGYMATMAAQGVPESLRGRDRIVFGNIQQIYEWHRDYFLQELQRCLKD PDWLAQLFIKHERRLHMYVVYCQNKPKSEHVVSEFGDSYFEELRQQLGHRLQLNDLLIKPVQRIMKYQLLLKDFLKYYNRAGMDTADLEK SGGLPSLGLTLANVTSDLNRKNVTCWAENDVGRAEVSVQVNVSFPASVQLHTAVEMHHWCIPFSVDGQPAPSLRWLFNGSVLNETSFIFT EFLEPAANETVRHGCLRLNQPTHVNNGNYTLLAANPFGQASASIMAAFMDNPFEFNPEDPIPVSFSPVDTNSTSGDPVEKKDETPFGVSV AVGLAVFACLFLSTLLLVLNKCGRRNKFGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDI VLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRF LRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLP IRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHAR >In-frame_ARHGEF25_ENST00000333972_chr12_58008800_+_NTRK1_ENST00000358660_chr1_156841415_+_914aa MKPPDRPAPGRTDRILGVMGGMLRACALPGQEGPPRRSPLGLVGTEPESERTEGDHRRDREHEVLAGALQPESYSIAGSEGSISASAASG LAAPSGPSSGLSSGPCSPGPPGPVSGLRRWLDHSKHCLSVETEADSGQAGPYENWMLEPALATGEELPELTLLTTLLEGPGDKTQPPEEE TLSQAPESEEEQKKKALERSMYVLSELVETEKMYVDDLGQIVEGYMATMAAQGVPESLRGRDRIVFGNIQQIYEWHRDYFLQELQRCLKD PDWLAQLFIKHERRLHMYVVYCQNKPKSEHVVSEFGDSYFEELRQQLGHRLQLNDLLIKPVQRIMKYQLLLKDFLKYYNRAGMDTADLEK SGGLPSLGLTLANVTSDLNRKNVTCWAENDVGRAEVSVQVNVSFPASVQLHTAVEMHHWCIPFSVDGQPAPSLRWLFNGSVLNETSFIFT EFLEPAANETVRHGCLRLNQPTHVNNGNYTLLAANPFGQASASIMAAFMDNPFEFNPEDPIPDTNSTSGDPVEKKDETPFGVSVAVGLAV FACLFLSTLLLVLNKCGRRNKFGINRPAVLAPEDGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDASPSGVHHIKRRDIVLK WELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRS HGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRW MPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGRELERPRACPPEVYAIMRGCWQREPQQRHSIKDVHARLQA >In-frame_ARHGEF25_ENST00000286494_chr12_58008800_+_NTRK1_ENST00000392302_chr1_156841415_+_872aa MRGGHKGGRCACPRVIRKVLAKCGCCFARGGRESYSIAGSEGSISASAASGLAAPSGPSSGLSSGPCSPGPPGPVSGLRRWLDHSKHCLS VETEADSGQAGPYENWMLEPALATGEELPELTLLTTLLEGPGDKTQPPEEETLSQAPESEEEQKKKALERSMYVLSELVETEKMYVDDLG QIVEGYMATMAAQGVPESLRGRDRIVFGNIQQIYEWHRDYFLQELQRCLKDPDWLAQLFIKHERRLHMYVVYCQNKPKSEHVVSEFGDSY FEELRQQLGHRLQLNDLLIKPVQRIMKYQLLLKDFLKYYNRAGMDTADLEKSGGLPSLGLTLANVTSDLNRKNVTCWAENDVGRAEVSVQ VNVSFPASVQLHTAVEMHHWCIPFSVDGQPAPSLRWLFNGSVLNETSFIFTEFLEPAANETVRHGCLRLNQPTHVNNGNYTLLAANPFGQ ASASIMAAFMDNPFEFNPEDPIPDTNSTSGDPVEKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNKFGINRPAVLAPEDGLAMS LHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQ DFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLH FVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTE >In-frame_ARHGEF25_ENST00000286494_chr12_58008800_+_NTRK1_ENST00000368196_chr1_156841415_+_872aa MRGGHKGGRCACPRVIRKVLAKCGCCFARGGRESYSIAGSEGSISASAASGLAAPSGPSSGLSSGPCSPGPPGPVSGLRRWLDHSKHCLS VETEADSGQAGPYENWMLEPALATGEELPELTLLTTLLEGPGDKTQPPEEETLSQAPESEEEQKKKALERSMYVLSELVETEKMYVDDLG QIVEGYMATMAAQGVPESLRGRDRIVFGNIQQIYEWHRDYFLQELQRCLKDPDWLAQLFIKHERRLHMYVVYCQNKPKSEHVVSEFGDSY FEELRQQLGHRLQLNDLLIKPVQRIMKYQLLLKDFLKYYNRAGMDTADLEKSGGLPSLGLTLANVTSDLNRKNVTCWAENDVGRAEVSVQ VNVSFPASVQLHTAVEMHHWCIPFSVDGQPAPSLRWLFNGSVLNETSFIFTEFLEPAANETVRHGCLRLNQPTHVNNGNYTLLAANPFGQ ASASIMAAFMDNPFEFNPEDPIPDTNSTSGDPVEKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNKFGINRPAVLAPEDGLAMS LHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQ DFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLH FVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTE >In-frame_ARHGEF25_ENST00000286494_chr12_58008800_+_NTRK1_ENST00000524377_chr1_156841415_+_878aa MRGGHKGGRCACPRVIRKVLAKCGCCFARGGRESYSIAGSEGSISASAASGLAAPSGPSSGLSSGPCSPGPPGPVSGLRRWLDHSKHCLS VETEADSGQAGPYENWMLEPALATGEELPELTLLTTLLEGPGDKTQPPEEETLSQAPESEEEQKKKALERSMYVLSELVETEKMYVDDLG QIVEGYMATMAAQGVPESLRGRDRIVFGNIQQIYEWHRDYFLQELQRCLKDPDWLAQLFIKHERRLHMYVVYCQNKPKSEHVVSEFGDSY FEELRQQLGHRLQLNDLLIKPVQRIMKYQLLLKDFLKYYNRAGMDTADLEKSGGLPSLGLTLANVTSDLNRKNVTCWAENDVGRAEVSVQ VNVSFPASVQLHTAVEMHHWCIPFSVDGQPAPSLRWLFNGSVLNETSFIFTEFLEPAANETVRHGCLRLNQPTHVNNGNYTLLAANPFGQ ASASIMAAFMDNPFEFNPEDPIPVSFSPVDTNSTSGDPVEKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNKFGINRPAVLAPE DGLAMSLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEA SESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMV YLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWY >In-frame_ARHGEF25_ENST00000286494_chr12_58008800_+_NTRK1_ENST00000358660_chr1_156841415_+_875aa MRGGHKGGRCACPRVIRKVLAKCGCCFARGGRESYSIAGSEGSISASAASGLAAPSGPSSGLSSGPCSPGPPGPVSGLRRWLDHSKHCLS VETEADSGQAGPYENWMLEPALATGEELPELTLLTTLLEGPGDKTQPPEEETLSQAPESEEEQKKKALERSMYVLSELVETEKMYVDDLG QIVEGYMATMAAQGVPESLRGRDRIVFGNIQQIYEWHRDYFLQELQRCLKDPDWLAQLFIKHERRLHMYVVYCQNKPKSEHVVSEFGDSY FEELRQQLGHRLQLNDLLIKPVQRIMKYQLLLKDFLKYYNRAGMDTADLEKSGGLPSLGLTLANVTSDLNRKNVTCWAENDVGRAEVSVQ VNVSFPASVQLHTAVEMHHWCIPFSVDGQPAPSLRWLFNGSVLNETSFIFTEFLEPAANETVRHGCLRLNQPTHVNNGNYTLLAANPFGQ ASASIMAAFMDNPFEFNPEDPIPDTNSTSGDPVEKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNKFGINRPAVLAPEDGLAMS LHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDASPSGVHHIKRRDIVLKWELGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASES ARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLA GLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLS |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_ARHGEF25_ENST00000333972_chr12_58008800_+_NTRK1_ENST00000392302_chr1_156841415_+_2733nt ATGAAGCCCCCGGACCGCCCCGCCCCTGGCCGCACTGACCGGATACTGGGGGTCATGGGGGGCATGCTGCGCGCATGCGCCCTCCCTGGG CAGGAGGGGCCCCCAAGGAGAAGCCCTCTAGGGTTGGTGGGTACCGAGCCAGAGTCTGAACGTACGGAGGGAGATCACAGAAGGGATCGC GAACATGAGGTCCTCGCCGGGGCTCTGCAGCCCGAATCCTATTCCATTGCGGGCAGTGAGGGGAGTATATCGGCTTCTGCTGCCTCCGGT CTGGCTGCCCCCTCTGGCCCCAGCTCTGGCCTCAGCTCTGGCCCCTGTTCCCCAGGCCCCCCAGGGCCCGTCAGTGGCCTGAGGAGATGG TTGGATCATTCCAAACATTGTCTCAGTGTGGAAACTGAGGCAGACAGTGGTCAGGCAGGACCATATGAGAACTGGATGTTGGAGCCAGCT CTAGCCACAGGAGAGGAGCTGCCGGAACTGACCTTGCTGACCACACTGTTGGAGGGCCCTGGAGATAAGACGCAGCCACCTGAAGAGGAG ACTTTGTCCCAAGCCCCTGAGAGTGAGGAGGAACAGAAGAAGAAGGCTCTGGAAAGGAGTATGTATGTCCTGAGTGAACTGGTAGAAACA GAGAAAATGTACGTGGACGACTTGGGGCAGATTGTGGAGGGTTATATGGCCACCATGGCTGCTCAGGGGGTCCCCGAGAGTCTTCGAGGC CGTGACAGGATTGTGTTTGGGAATATCCAGCAAATCTATGAGTGGCACCGAGACTATTTCTTGCAAGAGCTACAACGGTGTCTGAAAGAT CCTGATTGGCTGGCTCAGCTATTCATCAAACACGAGCGCCGGCTGCATATGTATGTGGTGTACTGTCAGAATAAGCCCAAGTCAGAGCAT GTGGTGTCAGAGTTTGGGGACAGCTACTTTGAGGAGCTCCGGCAGCAGCTGGGGCACCGCCTGCAGCTGAACGACCTCCTCATCAAACCT GTGCAGCGGATCATGAAATACCAGCTGCTGCTCAAGGATTTTCTCAAGTATTACAATAGAGCTGGGATGGATACTGCAGACCTAGAGAAA TCTGGGGGTCTGCCATCCCTGGGGCTGACCCTGGCCAATGTCACCAGTGACCTCAACAGGAAGAACGTGACGTGCTGGGCAGAGAACGAT GTGGGCCGGGCAGAGGTCTCTGTTCAGGTCAACGTCTCCTTCCCGGCCAGTGTGCAGCTGCACACGGCGGTGGAGATGCACCACTGGTGC ATCCCCTTCTCTGTGGATGGGCAGCCGGCACCGTCTCTGCGCTGGCTCTTCAATGGCTCCGTGCTCAATGAGACCAGCTTCATCTTCACT GAGTTCCTGGAGCCGGCAGCCAATGAGACCGTGCGGCACGGGTGTCTGCGCCTCAACCAGCCCACCCACGTCAACAACGGCAACTACACG CTGCTGGCTGCCAACCCCTTCGGCCAGGCCTCCGCCTCCATCATGGCTGCCTTCATGGACAACCCTTTCGAGTTCAACCCCGAGGACCCC ATCCCTGACACTAACAGCACATCTGGAGACCCGGTGGAGAAGAAGGACGAAACACCTTTTGGGGTCTCGGTGGCTGTGGGCCTGGCCGTC TTTGCCTGCCTCTTCCTTTCTACGCTGCTCCTTGTGCTCAACAAATGTGGACGGAGAAACAAGTTTGGGATCAACCGCCCGGCTGTGCTG GCTCCAGAGGATGGGCTGGCCATGTCCCTGCATTTCATGACATTGGGTGGCAGCTCCCTGTCCCCCACCGAGGGCAAAGGCTCTGGGCTC CAAGGCCACATCATCGAGAACCCACAATACTTCAGTGATGCCTGTGTTCACCACATCAAGCGCCGGGACATCGTGCTCAAGTGGGAGCTG GGGGAGGGCGCCTTTGGGAAGGTCTTCCTTGCTGAGTGCCACAACCTCCTGCCTGAGCAGGACAAGATGCTGGTGGCTGTCAAGGCACTG AAGGAGGCGTCCGAGAGTGCTCGGCAGGACTTCCAGCGTGAGGCTGAGCTGCTCACCATGCTGCAGCACCAGCACATCGTGCGCTTCTTC GGCGTCTGCACCGAGGGCCGCCCCCTGCTCATGGTCTTTGAGTATATGCGGCACGGGGACCTCAACCGCTTCCTCCGATCCCATGGACCT GATGCCAAGCTGCTGGCTGGTGGGGAGGATGTGGCTCCAGGCCCCCTGGGTCTGGGGCAGCTGCTGGCCGTGGCTAGCCAGGTCGCTGCG GGGATGGTGTACCTGGCGGGTCTGCATTTTGTGCACCGGGACCTGGCCACACGCAACTGTCTAGTGGGCCAGGGACTGGTGGTCAAGATT GGTGATTTTGGCATGAGCAGGGATATCTACAGCACCGACTATTACCGTGTGGGAGGCCGCACCATGCTGCCCATTCGCTGGATGCCGCCC GAGAGCATCCTGTACCGTAAGTTCACCACCGAGAGCGACGTGTGGAGCTTCGGCGTGGTGCTCTGGGAGATCTTCACCTACGGCAAGCAG CCCTGGTACCAGCTCTCCAACACGGAGGCAATCGACTGCATCACGCAGGGACGTGAGTTGGAGCGGCCACGTGCCTGCCCACCAGAGGTC TACGCCATCATGCGGGGCTGCTGGCAGCGGGAGCCCCAGCAACGCCACAGCATCAAGGATGTGCACGCCCGGCTGCAAGCCCTGGCCCAG >In-frame_ARHGEF25_ENST00000333972_chr12_58008800_+_NTRK1_ENST00000368196_chr1_156841415_+_2733nt ATGAAGCCCCCGGACCGCCCCGCCCCTGGCCGCACTGACCGGATACTGGGGGTCATGGGGGGCATGCTGCGCGCATGCGCCCTCCCTGGG CAGGAGGGGCCCCCAAGGAGAAGCCCTCTAGGGTTGGTGGGTACCGAGCCAGAGTCTGAACGTACGGAGGGAGATCACAGAAGGGATCGC GAACATGAGGTCCTCGCCGGGGCTCTGCAGCCCGAATCCTATTCCATTGCGGGCAGTGAGGGGAGTATATCGGCTTCTGCTGCCTCCGGT CTGGCTGCCCCCTCTGGCCCCAGCTCTGGCCTCAGCTCTGGCCCCTGTTCCCCAGGCCCCCCAGGGCCCGTCAGTGGCCTGAGGAGATGG TTGGATCATTCCAAACATTGTCTCAGTGTGGAAACTGAGGCAGACAGTGGTCAGGCAGGACCATATGAGAACTGGATGTTGGAGCCAGCT CTAGCCACAGGAGAGGAGCTGCCGGAACTGACCTTGCTGACCACACTGTTGGAGGGCCCTGGAGATAAGACGCAGCCACCTGAAGAGGAG ACTTTGTCCCAAGCCCCTGAGAGTGAGGAGGAACAGAAGAAGAAGGCTCTGGAAAGGAGTATGTATGTCCTGAGTGAACTGGTAGAAACA GAGAAAATGTACGTGGACGACTTGGGGCAGATTGTGGAGGGTTATATGGCCACCATGGCTGCTCAGGGGGTCCCCGAGAGTCTTCGAGGC CGTGACAGGATTGTGTTTGGGAATATCCAGCAAATCTATGAGTGGCACCGAGACTATTTCTTGCAAGAGCTACAACGGTGTCTGAAAGAT CCTGATTGGCTGGCTCAGCTATTCATCAAACACGAGCGCCGGCTGCATATGTATGTGGTGTACTGTCAGAATAAGCCCAAGTCAGAGCAT GTGGTGTCAGAGTTTGGGGACAGCTACTTTGAGGAGCTCCGGCAGCAGCTGGGGCACCGCCTGCAGCTGAACGACCTCCTCATCAAACCT GTGCAGCGGATCATGAAATACCAGCTGCTGCTCAAGGATTTTCTCAAGTATTACAATAGAGCTGGGATGGATACTGCAGACCTAGAGAAA TCTGGGGGTCTGCCATCCCTGGGGCTGACCCTGGCCAATGTCACCAGTGACCTCAACAGGAAGAACGTGACGTGCTGGGCAGAGAACGAT GTGGGCCGGGCAGAGGTCTCTGTTCAGGTCAACGTCTCCTTCCCGGCCAGTGTGCAGCTGCACACGGCGGTGGAGATGCACCACTGGTGC ATCCCCTTCTCTGTGGATGGGCAGCCGGCACCGTCTCTGCGCTGGCTCTTCAATGGCTCCGTGCTCAATGAGACCAGCTTCATCTTCACT GAGTTCCTGGAGCCGGCAGCCAATGAGACCGTGCGGCACGGGTGTCTGCGCCTCAACCAGCCCACCCACGTCAACAACGGCAACTACACG CTGCTGGCTGCCAACCCCTTCGGCCAGGCCTCCGCCTCCATCATGGCTGCCTTCATGGACAACCCTTTCGAGTTCAACCCCGAGGACCCC ATCCCTGACACTAACAGCACATCTGGAGACCCGGTGGAGAAGAAGGACGAAACACCTTTTGGGGTCTCGGTGGCTGTGGGCCTGGCCGTC TTTGCCTGCCTCTTCCTTTCTACGCTGCTCCTTGTGCTCAACAAATGTGGACGGAGAAACAAGTTTGGGATCAACCGCCCGGCTGTGCTG GCTCCAGAGGATGGGCTGGCCATGTCCCTGCATTTCATGACATTGGGTGGCAGCTCCCTGTCCCCCACCGAGGGCAAAGGCTCTGGGCTC CAAGGCCACATCATCGAGAACCCACAATACTTCAGTGATGCCTGTGTTCACCACATCAAGCGCCGGGACATCGTGCTCAAGTGGGAGCTG GGGGAGGGCGCCTTTGGGAAGGTCTTCCTTGCTGAGTGCCACAACCTCCTGCCTGAGCAGGACAAGATGCTGGTGGCTGTCAAGGCACTG AAGGAGGCGTCCGAGAGTGCTCGGCAGGACTTCCAGCGTGAGGCTGAGCTGCTCACCATGCTGCAGCACCAGCACATCGTGCGCTTCTTC GGCGTCTGCACCGAGGGCCGCCCCCTGCTCATGGTCTTTGAGTATATGCGGCACGGGGACCTCAACCGCTTCCTCCGATCCCATGGACCT GATGCCAAGCTGCTGGCTGGTGGGGAGGATGTGGCTCCAGGCCCCCTGGGTCTGGGGCAGCTGCTGGCCGTGGCTAGCCAGGTCGCTGCG GGGATGGTGTACCTGGCGGGTCTGCATTTTGTGCACCGGGACCTGGCCACACGCAACTGTCTAGTGGGCCAGGGACTGGTGGTCAAGATT GGTGATTTTGGCATGAGCAGGGATATCTACAGCACCGACTATTACCGTGTGGGAGGCCGCACCATGCTGCCCATTCGCTGGATGCCGCCC GAGAGCATCCTGTACCGTAAGTTCACCACCGAGAGCGACGTGTGGAGCTTCGGCGTGGTGCTCTGGGAGATCTTCACCTACGGCAAGCAG CCCTGGTACCAGCTCTCCAACACGGAGGCAATCGACTGCATCACGCAGGGACGTGAGTTGGAGCGGCCACGTGCCTGCCCACCAGAGGTC TACGCCATCATGCGGGGCTGCTGGCAGCGGGAGCCCCAGCAACGCCACAGCATCAAGGATGTGCACGCCCGGCTGCAAGCCCTGGCCCAG >In-frame_ARHGEF25_ENST00000333972_chr12_58008800_+_NTRK1_ENST00000524377_chr1_156841415_+_2751nt ATGAAGCCCCCGGACCGCCCCGCCCCTGGCCGCACTGACCGGATACTGGGGGTCATGGGGGGCATGCTGCGCGCATGCGCCCTCCCTGGG CAGGAGGGGCCCCCAAGGAGAAGCCCTCTAGGGTTGGTGGGTACCGAGCCAGAGTCTGAACGTACGGAGGGAGATCACAGAAGGGATCGC GAACATGAGGTCCTCGCCGGGGCTCTGCAGCCCGAATCCTATTCCATTGCGGGCAGTGAGGGGAGTATATCGGCTTCTGCTGCCTCCGGT CTGGCTGCCCCCTCTGGCCCCAGCTCTGGCCTCAGCTCTGGCCCCTGTTCCCCAGGCCCCCCAGGGCCCGTCAGTGGCCTGAGGAGATGG TTGGATCATTCCAAACATTGTCTCAGTGTGGAAACTGAGGCAGACAGTGGTCAGGCAGGACCATATGAGAACTGGATGTTGGAGCCAGCT CTAGCCACAGGAGAGGAGCTGCCGGAACTGACCTTGCTGACCACACTGTTGGAGGGCCCTGGAGATAAGACGCAGCCACCTGAAGAGGAG ACTTTGTCCCAAGCCCCTGAGAGTGAGGAGGAACAGAAGAAGAAGGCTCTGGAAAGGAGTATGTATGTCCTGAGTGAACTGGTAGAAACA GAGAAAATGTACGTGGACGACTTGGGGCAGATTGTGGAGGGTTATATGGCCACCATGGCTGCTCAGGGGGTCCCCGAGAGTCTTCGAGGC CGTGACAGGATTGTGTTTGGGAATATCCAGCAAATCTATGAGTGGCACCGAGACTATTTCTTGCAAGAGCTACAACGGTGTCTGAAAGAT CCTGATTGGCTGGCTCAGCTATTCATCAAACACGAGCGCCGGCTGCATATGTATGTGGTGTACTGTCAGAATAAGCCCAAGTCAGAGCAT GTGGTGTCAGAGTTTGGGGACAGCTACTTTGAGGAGCTCCGGCAGCAGCTGGGGCACCGCCTGCAGCTGAACGACCTCCTCATCAAACCT GTGCAGCGGATCATGAAATACCAGCTGCTGCTCAAGGATTTTCTCAAGTATTACAATAGAGCTGGGATGGATACTGCAGACCTAGAGAAA TCTGGGGGTCTGCCATCCCTGGGGCTGACCCTGGCCAATGTCACCAGTGACCTCAACAGGAAGAACGTGACGTGCTGGGCAGAGAACGAT GTGGGCCGGGCAGAGGTCTCTGTTCAGGTCAACGTCTCCTTCCCGGCCAGTGTGCAGCTGCACACGGCGGTGGAGATGCACCACTGGTGC ATCCCCTTCTCTGTGGATGGGCAGCCGGCACCGTCTCTGCGCTGGCTCTTCAATGGCTCCGTGCTCAATGAGACCAGCTTCATCTTCACT GAGTTCCTGGAGCCGGCAGCCAATGAGACCGTGCGGCACGGGTGTCTGCGCCTCAACCAGCCCACCCACGTCAACAACGGCAACTACACG CTGCTGGCTGCCAACCCCTTCGGCCAGGCCTCCGCCTCCATCATGGCTGCCTTCATGGACAACCCTTTCGAGTTCAACCCCGAGGACCCC ATCCCTGTCTCCTTCTCGCCGGTGGACACTAACAGCACATCTGGAGACCCGGTGGAGAAGAAGGACGAAACACCTTTTGGGGTCTCGGTG GCTGTGGGCCTGGCCGTCTTTGCCTGCCTCTTCCTTTCTACGCTGCTCCTTGTGCTCAACAAATGTGGACGGAGAAACAAGTTTGGGATC AACCGCCCGGCTGTGCTGGCTCCAGAGGATGGGCTGGCCATGTCCCTGCATTTCATGACATTGGGTGGCAGCTCCCTGTCCCCCACCGAG GGCAAAGGCTCTGGGCTCCAAGGCCACATCATCGAGAACCCACAATACTTCAGTGATGCCTGTGTTCACCACATCAAGCGCCGGGACATC GTGCTCAAGTGGGAGCTGGGGGAGGGCGCCTTTGGGAAGGTCTTCCTTGCTGAGTGCCACAACCTCCTGCCTGAGCAGGACAAGATGCTG GTGGCTGTCAAGGCACTGAAGGAGGCGTCCGAGAGTGCTCGGCAGGACTTCCAGCGTGAGGCTGAGCTGCTCACCATGCTGCAGCACCAG CACATCGTGCGCTTCTTCGGCGTCTGCACCGAGGGCCGCCCCCTGCTCATGGTCTTTGAGTATATGCGGCACGGGGACCTCAACCGCTTC CTCCGATCCCATGGACCTGATGCCAAGCTGCTGGCTGGTGGGGAGGATGTGGCTCCAGGCCCCCTGGGTCTGGGGCAGCTGCTGGCCGTG GCTAGCCAGGTCGCTGCGGGGATGGTGTACCTGGCGGGTCTGCATTTTGTGCACCGGGACCTGGCCACACGCAACTGTCTAGTGGGCCAG GGACTGGTGGTCAAGATTGGTGATTTTGGCATGAGCAGGGATATCTACAGCACCGACTATTACCGTGTGGGAGGCCGCACCATGCTGCCC ATTCGCTGGATGCCGCCCGAGAGCATCCTGTACCGTAAGTTCACCACCGAGAGCGACGTGTGGAGCTTCGGCGTGGTGCTCTGGGAGATC TTCACCTACGGCAAGCAGCCCTGGTACCAGCTCTCCAACACGGAGGCAATCGACTGCATCACGCAGGGACGTGAGTTGGAGCGGCCACGT GCCTGCCCACCAGAGGTCTACGCCATCATGCGGGGCTGCTGGCAGCGGGAGCCCCAGCAACGCCACAGCATCAAGGATGTGCACGCCCGG >In-frame_ARHGEF25_ENST00000333972_chr12_58008800_+_NTRK1_ENST00000358660_chr1_156841415_+_2742nt ATGAAGCCCCCGGACCGCCCCGCCCCTGGCCGCACTGACCGGATACTGGGGGTCATGGGGGGCATGCTGCGCGCATGCGCCCTCCCTGGG CAGGAGGGGCCCCCAAGGAGAAGCCCTCTAGGGTTGGTGGGTACCGAGCCAGAGTCTGAACGTACGGAGGGAGATCACAGAAGGGATCGC GAACATGAGGTCCTCGCCGGGGCTCTGCAGCCCGAATCCTATTCCATTGCGGGCAGTGAGGGGAGTATATCGGCTTCTGCTGCCTCCGGT CTGGCTGCCCCCTCTGGCCCCAGCTCTGGCCTCAGCTCTGGCCCCTGTTCCCCAGGCCCCCCAGGGCCCGTCAGTGGCCTGAGGAGATGG TTGGATCATTCCAAACATTGTCTCAGTGTGGAAACTGAGGCAGACAGTGGTCAGGCAGGACCATATGAGAACTGGATGTTGGAGCCAGCT CTAGCCACAGGAGAGGAGCTGCCGGAACTGACCTTGCTGACCACACTGTTGGAGGGCCCTGGAGATAAGACGCAGCCACCTGAAGAGGAG ACTTTGTCCCAAGCCCCTGAGAGTGAGGAGGAACAGAAGAAGAAGGCTCTGGAAAGGAGTATGTATGTCCTGAGTGAACTGGTAGAAACA GAGAAAATGTACGTGGACGACTTGGGGCAGATTGTGGAGGGTTATATGGCCACCATGGCTGCTCAGGGGGTCCCCGAGAGTCTTCGAGGC CGTGACAGGATTGTGTTTGGGAATATCCAGCAAATCTATGAGTGGCACCGAGACTATTTCTTGCAAGAGCTACAACGGTGTCTGAAAGAT CCTGATTGGCTGGCTCAGCTATTCATCAAACACGAGCGCCGGCTGCATATGTATGTGGTGTACTGTCAGAATAAGCCCAAGTCAGAGCAT GTGGTGTCAGAGTTTGGGGACAGCTACTTTGAGGAGCTCCGGCAGCAGCTGGGGCACCGCCTGCAGCTGAACGACCTCCTCATCAAACCT GTGCAGCGGATCATGAAATACCAGCTGCTGCTCAAGGATTTTCTCAAGTATTACAATAGAGCTGGGATGGATACTGCAGACCTAGAGAAA TCTGGGGGTCTGCCATCCCTGGGGCTGACCCTGGCCAATGTCACCAGTGACCTCAACAGGAAGAACGTGACGTGCTGGGCAGAGAACGAT GTGGGCCGGGCAGAGGTCTCTGTTCAGGTCAACGTCTCCTTCCCGGCCAGTGTGCAGCTGCACACGGCGGTGGAGATGCACCACTGGTGC ATCCCCTTCTCTGTGGATGGGCAGCCGGCACCGTCTCTGCGCTGGCTCTTCAATGGCTCCGTGCTCAATGAGACCAGCTTCATCTTCACT GAGTTCCTGGAGCCGGCAGCCAATGAGACCGTGCGGCACGGGTGTCTGCGCCTCAACCAGCCCACCCACGTCAACAACGGCAACTACACG CTGCTGGCTGCCAACCCCTTCGGCCAGGCCTCCGCCTCCATCATGGCTGCCTTCATGGACAACCCTTTCGAGTTCAACCCCGAGGACCCC ATCCCTGACACTAACAGCACATCTGGAGACCCGGTGGAGAAGAAGGACGAAACACCTTTTGGGGTCTCGGTGGCTGTGGGCCTGGCCGTC TTTGCCTGCCTCTTCCTTTCTACGCTGCTCCTTGTGCTCAACAAATGTGGACGGAGAAACAAGTTTGGGATCAACCGCCCGGCTGTGCTG GCTCCAGAGGATGGGCTGGCCATGTCCCTGCATTTCATGACATTGGGTGGCAGCTCCCTGTCCCCCACCGAGGGCAAAGGCTCTGGGCTC CAAGGCCACATCATCGAGAACCCACAATACTTCAGTGATGCCTCCCCCTCAGGTGTTCACCACATCAAGCGCCGGGACATCGTGCTCAAG TGGGAGCTGGGGGAGGGCGCCTTTGGGAAGGTCTTCCTTGCTGAGTGCCACAACCTCCTGCCTGAGCAGGACAAGATGCTGGTGGCTGTC AAGGCACTGAAGGAGGCGTCCGAGAGTGCTCGGCAGGACTTCCAGCGTGAGGCTGAGCTGCTCACCATGCTGCAGCACCAGCACATCGTG CGCTTCTTCGGCGTCTGCACCGAGGGCCGCCCCCTGCTCATGGTCTTTGAGTATATGCGGCACGGGGACCTCAACCGCTTCCTCCGATCC CATGGACCTGATGCCAAGCTGCTGGCTGGTGGGGAGGATGTGGCTCCAGGCCCCCTGGGTCTGGGGCAGCTGCTGGCCGTGGCTAGCCAG GTCGCTGCGGGGATGGTGTACCTGGCGGGTCTGCATTTTGTGCACCGGGACCTGGCCACACGCAACTGTCTAGTGGGCCAGGGACTGGTG GTCAAGATTGGTGATTTTGGCATGAGCAGGGATATCTACAGCACCGACTATTACCGTGTGGGAGGCCGCACCATGCTGCCCATTCGCTGG ATGCCGCCCGAGAGCATCCTGTACCGTAAGTTCACCACCGAGAGCGACGTGTGGAGCTTCGGCGTGGTGCTCTGGGAGATCTTCACCTAC GGCAAGCAGCCCTGGTACCAGCTCTCCAACACGGAGGCAATCGACTGCATCACGCAGGGACGTGAGTTGGAGCGGCCACGTGCCTGCCCA CCAGAGGTCTACGCCATCATGCGGGGCTGCTGGCAGCGGGAGCCCCAGCAACGCCACAGCATCAAGGATGTGCACGCCCGGCTGCAAGCC >In-frame_ARHGEF25_ENST00000286494_chr12_58008800_+_NTRK1_ENST00000392302_chr1_156841415_+_2616nt ATGCGGGGGGGGCACAAAGGGGGTCGCTGTGCCTGTCCCCGTGTGATCCGAAAAGTGCTGGCAAAATGCGGCTGCTGCTTCGCCCGGGGG GGACGTGAATCCTATTCCATTGCGGGCAGTGAGGGGAGTATATCGGCTTCTGCTGCCTCCGGTCTGGCTGCCCCCTCTGGCCCCAGCTCT GGCCTCAGCTCTGGCCCCTGTTCCCCAGGCCCCCCAGGGCCCGTCAGTGGCCTGAGGAGATGGTTGGATCATTCCAAACATTGTCTCAGT GTGGAAACTGAGGCAGACAGTGGTCAGGCAGGACCATATGAGAACTGGATGTTGGAGCCAGCTCTAGCCACAGGAGAGGAGCTGCCGGAA CTGACCTTGCTGACCACACTGTTGGAGGGCCCTGGAGATAAGACGCAGCCACCTGAAGAGGAGACTTTGTCCCAAGCCCCTGAGAGTGAG GAGGAACAGAAGAAGAAGGCTCTGGAAAGGAGTATGTATGTCCTGAGTGAACTGGTAGAAACAGAGAAAATGTACGTGGACGACTTGGGG CAGATTGTGGAGGGTTATATGGCCACCATGGCTGCTCAGGGGGTCCCCGAGAGTCTTCGAGGCCGTGACAGGATTGTGTTTGGGAATATC CAGCAAATCTATGAGTGGCACCGAGACTATTTCTTGCAAGAGCTACAACGGTGTCTGAAAGATCCTGATTGGCTGGCTCAGCTATTCATC AAACACGAGCGCCGGCTGCATATGTATGTGGTGTACTGTCAGAATAAGCCCAAGTCAGAGCATGTGGTGTCAGAGTTTGGGGACAGCTAC TTTGAGGAGCTCCGGCAGCAGCTGGGGCACCGCCTGCAGCTGAACGACCTCCTCATCAAACCTGTGCAGCGGATCATGAAATACCAGCTG CTGCTCAAGGATTTTCTCAAGTATTACAATAGAGCTGGGATGGATACTGCAGACCTAGAGAAATCTGGGGGTCTGCCATCCCTGGGGCTG ACCCTGGCCAATGTCACCAGTGACCTCAACAGGAAGAACGTGACGTGCTGGGCAGAGAACGATGTGGGCCGGGCAGAGGTCTCTGTTCAG GTCAACGTCTCCTTCCCGGCCAGTGTGCAGCTGCACACGGCGGTGGAGATGCACCACTGGTGCATCCCCTTCTCTGTGGATGGGCAGCCG GCACCGTCTCTGCGCTGGCTCTTCAATGGCTCCGTGCTCAATGAGACCAGCTTCATCTTCACTGAGTTCCTGGAGCCGGCAGCCAATGAG ACCGTGCGGCACGGGTGTCTGCGCCTCAACCAGCCCACCCACGTCAACAACGGCAACTACACGCTGCTGGCTGCCAACCCCTTCGGCCAG GCCTCCGCCTCCATCATGGCTGCCTTCATGGACAACCCTTTCGAGTTCAACCCCGAGGACCCCATCCCTGACACTAACAGCACATCTGGA GACCCGGTGGAGAAGAAGGACGAAACACCTTTTGGGGTCTCGGTGGCTGTGGGCCTGGCCGTCTTTGCCTGCCTCTTCCTTTCTACGCTG CTCCTTGTGCTCAACAAATGTGGACGGAGAAACAAGTTTGGGATCAACCGCCCGGCTGTGCTGGCTCCAGAGGATGGGCTGGCCATGTCC CTGCATTTCATGACATTGGGTGGCAGCTCCCTGTCCCCCACCGAGGGCAAAGGCTCTGGGCTCCAAGGCCACATCATCGAGAACCCACAA TACTTCAGTGATGCCTGTGTTCACCACATCAAGCGCCGGGACATCGTGCTCAAGTGGGAGCTGGGGGAGGGCGCCTTTGGGAAGGTCTTC CTTGCTGAGTGCCACAACCTCCTGCCTGAGCAGGACAAGATGCTGGTGGCTGTCAAGGCACTGAAGGAGGCGTCCGAGAGTGCTCGGCAG GACTTCCAGCGTGAGGCTGAGCTGCTCACCATGCTGCAGCACCAGCACATCGTGCGCTTCTTCGGCGTCTGCACCGAGGGCCGCCCCCTG CTCATGGTCTTTGAGTATATGCGGCACGGGGACCTCAACCGCTTCCTCCGATCCCATGGACCTGATGCCAAGCTGCTGGCTGGTGGGGAG GATGTGGCTCCAGGCCCCCTGGGTCTGGGGCAGCTGCTGGCCGTGGCTAGCCAGGTCGCTGCGGGGATGGTGTACCTGGCGGGTCTGCAT TTTGTGCACCGGGACCTGGCCACACGCAACTGTCTAGTGGGCCAGGGACTGGTGGTCAAGATTGGTGATTTTGGCATGAGCAGGGATATC TACAGCACCGACTATTACCGTGTGGGAGGCCGCACCATGCTGCCCATTCGCTGGATGCCGCCCGAGAGCATCCTGTACCGTAAGTTCACC ACCGAGAGCGACGTGTGGAGCTTCGGCGTGGTGCTCTGGGAGATCTTCACCTACGGCAAGCAGCCCTGGTACCAGCTCTCCAACACGGAG GCAATCGACTGCATCACGCAGGGACGTGAGTTGGAGCGGCCACGTGCCTGCCCACCAGAGGTCTACGCCATCATGCGGGGCTGCTGGCAG CGGGAGCCCCAGCAACGCCACAGCATCAAGGATGTGCACGCCCGGCTGCAAGCCCTGGCCCAGGCACCTCCTGTCTACCTGGATGTCCTG >In-frame_ARHGEF25_ENST00000286494_chr12_58008800_+_NTRK1_ENST00000368196_chr1_156841415_+_2616nt ATGCGGGGGGGGCACAAAGGGGGTCGCTGTGCCTGTCCCCGTGTGATCCGAAAAGTGCTGGCAAAATGCGGCTGCTGCTTCGCCCGGGGG GGACGTGAATCCTATTCCATTGCGGGCAGTGAGGGGAGTATATCGGCTTCTGCTGCCTCCGGTCTGGCTGCCCCCTCTGGCCCCAGCTCT GGCCTCAGCTCTGGCCCCTGTTCCCCAGGCCCCCCAGGGCCCGTCAGTGGCCTGAGGAGATGGTTGGATCATTCCAAACATTGTCTCAGT GTGGAAACTGAGGCAGACAGTGGTCAGGCAGGACCATATGAGAACTGGATGTTGGAGCCAGCTCTAGCCACAGGAGAGGAGCTGCCGGAA CTGACCTTGCTGACCACACTGTTGGAGGGCCCTGGAGATAAGACGCAGCCACCTGAAGAGGAGACTTTGTCCCAAGCCCCTGAGAGTGAG GAGGAACAGAAGAAGAAGGCTCTGGAAAGGAGTATGTATGTCCTGAGTGAACTGGTAGAAACAGAGAAAATGTACGTGGACGACTTGGGG CAGATTGTGGAGGGTTATATGGCCACCATGGCTGCTCAGGGGGTCCCCGAGAGTCTTCGAGGCCGTGACAGGATTGTGTTTGGGAATATC CAGCAAATCTATGAGTGGCACCGAGACTATTTCTTGCAAGAGCTACAACGGTGTCTGAAAGATCCTGATTGGCTGGCTCAGCTATTCATC AAACACGAGCGCCGGCTGCATATGTATGTGGTGTACTGTCAGAATAAGCCCAAGTCAGAGCATGTGGTGTCAGAGTTTGGGGACAGCTAC TTTGAGGAGCTCCGGCAGCAGCTGGGGCACCGCCTGCAGCTGAACGACCTCCTCATCAAACCTGTGCAGCGGATCATGAAATACCAGCTG CTGCTCAAGGATTTTCTCAAGTATTACAATAGAGCTGGGATGGATACTGCAGACCTAGAGAAATCTGGGGGTCTGCCATCCCTGGGGCTG ACCCTGGCCAATGTCACCAGTGACCTCAACAGGAAGAACGTGACGTGCTGGGCAGAGAACGATGTGGGCCGGGCAGAGGTCTCTGTTCAG GTCAACGTCTCCTTCCCGGCCAGTGTGCAGCTGCACACGGCGGTGGAGATGCACCACTGGTGCATCCCCTTCTCTGTGGATGGGCAGCCG GCACCGTCTCTGCGCTGGCTCTTCAATGGCTCCGTGCTCAATGAGACCAGCTTCATCTTCACTGAGTTCCTGGAGCCGGCAGCCAATGAG ACCGTGCGGCACGGGTGTCTGCGCCTCAACCAGCCCACCCACGTCAACAACGGCAACTACACGCTGCTGGCTGCCAACCCCTTCGGCCAG GCCTCCGCCTCCATCATGGCTGCCTTCATGGACAACCCTTTCGAGTTCAACCCCGAGGACCCCATCCCTGACACTAACAGCACATCTGGA GACCCGGTGGAGAAGAAGGACGAAACACCTTTTGGGGTCTCGGTGGCTGTGGGCCTGGCCGTCTTTGCCTGCCTCTTCCTTTCTACGCTG CTCCTTGTGCTCAACAAATGTGGACGGAGAAACAAGTTTGGGATCAACCGCCCGGCTGTGCTGGCTCCAGAGGATGGGCTGGCCATGTCC CTGCATTTCATGACATTGGGTGGCAGCTCCCTGTCCCCCACCGAGGGCAAAGGCTCTGGGCTCCAAGGCCACATCATCGAGAACCCACAA TACTTCAGTGATGCCTGTGTTCACCACATCAAGCGCCGGGACATCGTGCTCAAGTGGGAGCTGGGGGAGGGCGCCTTTGGGAAGGTCTTC CTTGCTGAGTGCCACAACCTCCTGCCTGAGCAGGACAAGATGCTGGTGGCTGTCAAGGCACTGAAGGAGGCGTCCGAGAGTGCTCGGCAG GACTTCCAGCGTGAGGCTGAGCTGCTCACCATGCTGCAGCACCAGCACATCGTGCGCTTCTTCGGCGTCTGCACCGAGGGCCGCCCCCTG CTCATGGTCTTTGAGTATATGCGGCACGGGGACCTCAACCGCTTCCTCCGATCCCATGGACCTGATGCCAAGCTGCTGGCTGGTGGGGAG GATGTGGCTCCAGGCCCCCTGGGTCTGGGGCAGCTGCTGGCCGTGGCTAGCCAGGTCGCTGCGGGGATGGTGTACCTGGCGGGTCTGCAT TTTGTGCACCGGGACCTGGCCACACGCAACTGTCTAGTGGGCCAGGGACTGGTGGTCAAGATTGGTGATTTTGGCATGAGCAGGGATATC TACAGCACCGACTATTACCGTGTGGGAGGCCGCACCATGCTGCCCATTCGCTGGATGCCGCCCGAGAGCATCCTGTACCGTAAGTTCACC ACCGAGAGCGACGTGTGGAGCTTCGGCGTGGTGCTCTGGGAGATCTTCACCTACGGCAAGCAGCCCTGGTACCAGCTCTCCAACACGGAG GCAATCGACTGCATCACGCAGGGACGTGAGTTGGAGCGGCCACGTGCCTGCCCACCAGAGGTCTACGCCATCATGCGGGGCTGCTGGCAG CGGGAGCCCCAGCAACGCCACAGCATCAAGGATGTGCACGCCCGGCTGCAAGCCCTGGCCCAGGCACCTCCTGTCTACCTGGATGTCCTG >In-frame_ARHGEF25_ENST00000286494_chr12_58008800_+_NTRK1_ENST00000524377_chr1_156841415_+_2634nt ATGCGGGGGGGGCACAAAGGGGGTCGCTGTGCCTGTCCCCGTGTGATCCGAAAAGTGCTGGCAAAATGCGGCTGCTGCTTCGCCCGGGGG GGACGTGAATCCTATTCCATTGCGGGCAGTGAGGGGAGTATATCGGCTTCTGCTGCCTCCGGTCTGGCTGCCCCCTCTGGCCCCAGCTCT GGCCTCAGCTCTGGCCCCTGTTCCCCAGGCCCCCCAGGGCCCGTCAGTGGCCTGAGGAGATGGTTGGATCATTCCAAACATTGTCTCAGT GTGGAAACTGAGGCAGACAGTGGTCAGGCAGGACCATATGAGAACTGGATGTTGGAGCCAGCTCTAGCCACAGGAGAGGAGCTGCCGGAA CTGACCTTGCTGACCACACTGTTGGAGGGCCCTGGAGATAAGACGCAGCCACCTGAAGAGGAGACTTTGTCCCAAGCCCCTGAGAGTGAG GAGGAACAGAAGAAGAAGGCTCTGGAAAGGAGTATGTATGTCCTGAGTGAACTGGTAGAAACAGAGAAAATGTACGTGGACGACTTGGGG CAGATTGTGGAGGGTTATATGGCCACCATGGCTGCTCAGGGGGTCCCCGAGAGTCTTCGAGGCCGTGACAGGATTGTGTTTGGGAATATC CAGCAAATCTATGAGTGGCACCGAGACTATTTCTTGCAAGAGCTACAACGGTGTCTGAAAGATCCTGATTGGCTGGCTCAGCTATTCATC AAACACGAGCGCCGGCTGCATATGTATGTGGTGTACTGTCAGAATAAGCCCAAGTCAGAGCATGTGGTGTCAGAGTTTGGGGACAGCTAC TTTGAGGAGCTCCGGCAGCAGCTGGGGCACCGCCTGCAGCTGAACGACCTCCTCATCAAACCTGTGCAGCGGATCATGAAATACCAGCTG CTGCTCAAGGATTTTCTCAAGTATTACAATAGAGCTGGGATGGATACTGCAGACCTAGAGAAATCTGGGGGTCTGCCATCCCTGGGGCTG ACCCTGGCCAATGTCACCAGTGACCTCAACAGGAAGAACGTGACGTGCTGGGCAGAGAACGATGTGGGCCGGGCAGAGGTCTCTGTTCAG GTCAACGTCTCCTTCCCGGCCAGTGTGCAGCTGCACACGGCGGTGGAGATGCACCACTGGTGCATCCCCTTCTCTGTGGATGGGCAGCCG GCACCGTCTCTGCGCTGGCTCTTCAATGGCTCCGTGCTCAATGAGACCAGCTTCATCTTCACTGAGTTCCTGGAGCCGGCAGCCAATGAG ACCGTGCGGCACGGGTGTCTGCGCCTCAACCAGCCCACCCACGTCAACAACGGCAACTACACGCTGCTGGCTGCCAACCCCTTCGGCCAG GCCTCCGCCTCCATCATGGCTGCCTTCATGGACAACCCTTTCGAGTTCAACCCCGAGGACCCCATCCCTGTCTCCTTCTCGCCGGTGGAC ACTAACAGCACATCTGGAGACCCGGTGGAGAAGAAGGACGAAACACCTTTTGGGGTCTCGGTGGCTGTGGGCCTGGCCGTCTTTGCCTGC CTCTTCCTTTCTACGCTGCTCCTTGTGCTCAACAAATGTGGACGGAGAAACAAGTTTGGGATCAACCGCCCGGCTGTGCTGGCTCCAGAG GATGGGCTGGCCATGTCCCTGCATTTCATGACATTGGGTGGCAGCTCCCTGTCCCCCACCGAGGGCAAAGGCTCTGGGCTCCAAGGCCAC ATCATCGAGAACCCACAATACTTCAGTGATGCCTGTGTTCACCACATCAAGCGCCGGGACATCGTGCTCAAGTGGGAGCTGGGGGAGGGC GCCTTTGGGAAGGTCTTCCTTGCTGAGTGCCACAACCTCCTGCCTGAGCAGGACAAGATGCTGGTGGCTGTCAAGGCACTGAAGGAGGCG TCCGAGAGTGCTCGGCAGGACTTCCAGCGTGAGGCTGAGCTGCTCACCATGCTGCAGCACCAGCACATCGTGCGCTTCTTCGGCGTCTGC ACCGAGGGCCGCCCCCTGCTCATGGTCTTTGAGTATATGCGGCACGGGGACCTCAACCGCTTCCTCCGATCCCATGGACCTGATGCCAAG CTGCTGGCTGGTGGGGAGGATGTGGCTCCAGGCCCCCTGGGTCTGGGGCAGCTGCTGGCCGTGGCTAGCCAGGTCGCTGCGGGGATGGTG TACCTGGCGGGTCTGCATTTTGTGCACCGGGACCTGGCCACACGCAACTGTCTAGTGGGCCAGGGACTGGTGGTCAAGATTGGTGATTTT GGCATGAGCAGGGATATCTACAGCACCGACTATTACCGTGTGGGAGGCCGCACCATGCTGCCCATTCGCTGGATGCCGCCCGAGAGCATC CTGTACCGTAAGTTCACCACCGAGAGCGACGTGTGGAGCTTCGGCGTGGTGCTCTGGGAGATCTTCACCTACGGCAAGCAGCCCTGGTAC CAGCTCTCCAACACGGAGGCAATCGACTGCATCACGCAGGGACGTGAGTTGGAGCGGCCACGTGCCTGCCCACCAGAGGTCTACGCCATC ATGCGGGGCTGCTGGCAGCGGGAGCCCCAGCAACGCCACAGCATCAAGGATGTGCACGCCCGGCTGCAAGCCCTGGCCCAGGCACCTCCT >In-frame_ARHGEF25_ENST00000286494_chr12_58008800_+_NTRK1_ENST00000358660_chr1_156841415_+_2625nt ATGCGGGGGGGGCACAAAGGGGGTCGCTGTGCCTGTCCCCGTGTGATCCGAAAAGTGCTGGCAAAATGCGGCTGCTGCTTCGCCCGGGGG GGACGTGAATCCTATTCCATTGCGGGCAGTGAGGGGAGTATATCGGCTTCTGCTGCCTCCGGTCTGGCTGCCCCCTCTGGCCCCAGCTCT GGCCTCAGCTCTGGCCCCTGTTCCCCAGGCCCCCCAGGGCCCGTCAGTGGCCTGAGGAGATGGTTGGATCATTCCAAACATTGTCTCAGT GTGGAAACTGAGGCAGACAGTGGTCAGGCAGGACCATATGAGAACTGGATGTTGGAGCCAGCTCTAGCCACAGGAGAGGAGCTGCCGGAA CTGACCTTGCTGACCACACTGTTGGAGGGCCCTGGAGATAAGACGCAGCCACCTGAAGAGGAGACTTTGTCCCAAGCCCCTGAGAGTGAG GAGGAACAGAAGAAGAAGGCTCTGGAAAGGAGTATGTATGTCCTGAGTGAACTGGTAGAAACAGAGAAAATGTACGTGGACGACTTGGGG CAGATTGTGGAGGGTTATATGGCCACCATGGCTGCTCAGGGGGTCCCCGAGAGTCTTCGAGGCCGTGACAGGATTGTGTTTGGGAATATC CAGCAAATCTATGAGTGGCACCGAGACTATTTCTTGCAAGAGCTACAACGGTGTCTGAAAGATCCTGATTGGCTGGCTCAGCTATTCATC AAACACGAGCGCCGGCTGCATATGTATGTGGTGTACTGTCAGAATAAGCCCAAGTCAGAGCATGTGGTGTCAGAGTTTGGGGACAGCTAC TTTGAGGAGCTCCGGCAGCAGCTGGGGCACCGCCTGCAGCTGAACGACCTCCTCATCAAACCTGTGCAGCGGATCATGAAATACCAGCTG CTGCTCAAGGATTTTCTCAAGTATTACAATAGAGCTGGGATGGATACTGCAGACCTAGAGAAATCTGGGGGTCTGCCATCCCTGGGGCTG ACCCTGGCCAATGTCACCAGTGACCTCAACAGGAAGAACGTGACGTGCTGGGCAGAGAACGATGTGGGCCGGGCAGAGGTCTCTGTTCAG GTCAACGTCTCCTTCCCGGCCAGTGTGCAGCTGCACACGGCGGTGGAGATGCACCACTGGTGCATCCCCTTCTCTGTGGATGGGCAGCCG GCACCGTCTCTGCGCTGGCTCTTCAATGGCTCCGTGCTCAATGAGACCAGCTTCATCTTCACTGAGTTCCTGGAGCCGGCAGCCAATGAG ACCGTGCGGCACGGGTGTCTGCGCCTCAACCAGCCCACCCACGTCAACAACGGCAACTACACGCTGCTGGCTGCCAACCCCTTCGGCCAG GCCTCCGCCTCCATCATGGCTGCCTTCATGGACAACCCTTTCGAGTTCAACCCCGAGGACCCCATCCCTGACACTAACAGCACATCTGGA GACCCGGTGGAGAAGAAGGACGAAACACCTTTTGGGGTCTCGGTGGCTGTGGGCCTGGCCGTCTTTGCCTGCCTCTTCCTTTCTACGCTG CTCCTTGTGCTCAACAAATGTGGACGGAGAAACAAGTTTGGGATCAACCGCCCGGCTGTGCTGGCTCCAGAGGATGGGCTGGCCATGTCC CTGCATTTCATGACATTGGGTGGCAGCTCCCTGTCCCCCACCGAGGGCAAAGGCTCTGGGCTCCAAGGCCACATCATCGAGAACCCACAA TACTTCAGTGATGCCTCCCCCTCAGGTGTTCACCACATCAAGCGCCGGGACATCGTGCTCAAGTGGGAGCTGGGGGAGGGCGCCTTTGGG AAGGTCTTCCTTGCTGAGTGCCACAACCTCCTGCCTGAGCAGGACAAGATGCTGGTGGCTGTCAAGGCACTGAAGGAGGCGTCCGAGAGT GCTCGGCAGGACTTCCAGCGTGAGGCTGAGCTGCTCACCATGCTGCAGCACCAGCACATCGTGCGCTTCTTCGGCGTCTGCACCGAGGGC CGCCCCCTGCTCATGGTCTTTGAGTATATGCGGCACGGGGACCTCAACCGCTTCCTCCGATCCCATGGACCTGATGCCAAGCTGCTGGCT GGTGGGGAGGATGTGGCTCCAGGCCCCCTGGGTCTGGGGCAGCTGCTGGCCGTGGCTAGCCAGGTCGCTGCGGGGATGGTGTACCTGGCG GGTCTGCATTTTGTGCACCGGGACCTGGCCACACGCAACTGTCTAGTGGGCCAGGGACTGGTGGTCAAGATTGGTGATTTTGGCATGAGC AGGGATATCTACAGCACCGACTATTACCGTGTGGGAGGCCGCACCATGCTGCCCATTCGCTGGATGCCGCCCGAGAGCATCCTGTACCGT AAGTTCACCACCGAGAGCGACGTGTGGAGCTTCGGCGTGGTGCTCTGGGAGATCTTCACCTACGGCAAGCAGCCCTGGTACCAGCTCTCC AACACGGAGGCAATCGACTGCATCACGCAGGGACGTGAGTTGGAGCGGCCACGTGCCTGCCCACCAGAGGTCTACGCCATCATGCGGGGC TGCTGGCAGCGGGAGCCCCAGCAACGCCACAGCATCAAGGATGTGCACGCCCGGCTGCAAGCCCTGGCCCAGGCACCTCCTGTCTACCTG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_ARHGEF25_ENST00000333972_chr12_58008800_+_NTRK1_ENST00000392302_chr1_156841415_+_2922nt CTCGACCCTGAAACTTGGAGCAGGGTGGGGGTTCAGTATGAAGCCCCCGGACCGCCCCGCCCCTGGCCGCACTGACCGGATACTGGGGGT CATGGGGGGCATGCTGCGCGCATGCGCCCTCCCTGGGCAGGAGGGGCCCCCAAGGAGAAGCCCTCTAGGGTTGGTGGGTACCGAGCCAGA GTCTGAACGTACGGAGGGAGATCACAGAAGGGATCGCGAACATGAGGTCCTCGCCGGGGCTCTGCAGCCCGAATCCTATTCCATTGCGGG CAGTGAGGGGAGTATATCGGCTTCTGCTGCCTCCGGTCTGGCTGCCCCCTCTGGCCCCAGCTCTGGCCTCAGCTCTGGCCCCTGTTCCCC AGGCCCCCCAGGGCCCGTCAGTGGCCTGAGGAGATGGTTGGATCATTCCAAACATTGTCTCAGTGTGGAAACTGAGGCAGACAGTGGTCA GGCAGGACCATATGAGAACTGGATGTTGGAGCCAGCTCTAGCCACAGGAGAGGAGCTGCCGGAACTGACCTTGCTGACCACACTGTTGGA GGGCCCTGGAGATAAGACGCAGCCACCTGAAGAGGAGACTTTGTCCCAAGCCCCTGAGAGTGAGGAGGAACAGAAGAAGAAGGCTCTGGA AAGGAGTATGTATGTCCTGAGTGAACTGGTAGAAACAGAGAAAATGTACGTGGACGACTTGGGGCAGATTGTGGAGGGTTATATGGCCAC CATGGCTGCTCAGGGGGTCCCCGAGAGTCTTCGAGGCCGTGACAGGATTGTGTTTGGGAATATCCAGCAAATCTATGAGTGGCACCGAGA CTATTTCTTGCAAGAGCTACAACGGTGTCTGAAAGATCCTGATTGGCTGGCTCAGCTATTCATCAAACACGAGCGCCGGCTGCATATGTA TGTGGTGTACTGTCAGAATAAGCCCAAGTCAGAGCATGTGGTGTCAGAGTTTGGGGACAGCTACTTTGAGGAGCTCCGGCAGCAGCTGGG GCACCGCCTGCAGCTGAACGACCTCCTCATCAAACCTGTGCAGCGGATCATGAAATACCAGCTGCTGCTCAAGGATTTTCTCAAGTATTA CAATAGAGCTGGGATGGATACTGCAGACCTAGAGAAATCTGGGGGTCTGCCATCCCTGGGGCTGACCCTGGCCAATGTCACCAGTGACCT CAACAGGAAGAACGTGACGTGCTGGGCAGAGAACGATGTGGGCCGGGCAGAGGTCTCTGTTCAGGTCAACGTCTCCTTCCCGGCCAGTGT GCAGCTGCACACGGCGGTGGAGATGCACCACTGGTGCATCCCCTTCTCTGTGGATGGGCAGCCGGCACCGTCTCTGCGCTGGCTCTTCAA TGGCTCCGTGCTCAATGAGACCAGCTTCATCTTCACTGAGTTCCTGGAGCCGGCAGCCAATGAGACCGTGCGGCACGGGTGTCTGCGCCT CAACCAGCCCACCCACGTCAACAACGGCAACTACACGCTGCTGGCTGCCAACCCCTTCGGCCAGGCCTCCGCCTCCATCATGGCTGCCTT CATGGACAACCCTTTCGAGTTCAACCCCGAGGACCCCATCCCTGACACTAACAGCACATCTGGAGACCCGGTGGAGAAGAAGGACGAAAC ACCTTTTGGGGTCTCGGTGGCTGTGGGCCTGGCCGTCTTTGCCTGCCTCTTCCTTTCTACGCTGCTCCTTGTGCTCAACAAATGTGGACG GAGAAACAAGTTTGGGATCAACCGCCCGGCTGTGCTGGCTCCAGAGGATGGGCTGGCCATGTCCCTGCATTTCATGACATTGGGTGGCAG CTCCCTGTCCCCCACCGAGGGCAAAGGCTCTGGGCTCCAAGGCCACATCATCGAGAACCCACAATACTTCAGTGATGCCTGTGTTCACCA CATCAAGCGCCGGGACATCGTGCTCAAGTGGGAGCTGGGGGAGGGCGCCTTTGGGAAGGTCTTCCTTGCTGAGTGCCACAACCTCCTGCC TGAGCAGGACAAGATGCTGGTGGCTGTCAAGGCACTGAAGGAGGCGTCCGAGAGTGCTCGGCAGGACTTCCAGCGTGAGGCTGAGCTGCT CACCATGCTGCAGCACCAGCACATCGTGCGCTTCTTCGGCGTCTGCACCGAGGGCCGCCCCCTGCTCATGGTCTTTGAGTATATGCGGCA CGGGGACCTCAACCGCTTCCTCCGATCCCATGGACCTGATGCCAAGCTGCTGGCTGGTGGGGAGGATGTGGCTCCAGGCCCCCTGGGTCT GGGGCAGCTGCTGGCCGTGGCTAGCCAGGTCGCTGCGGGGATGGTGTACCTGGCGGGTCTGCATTTTGTGCACCGGGACCTGGCCACACG CAACTGTCTAGTGGGCCAGGGACTGGTGGTCAAGATTGGTGATTTTGGCATGAGCAGGGATATCTACAGCACCGACTATTACCGTGTGGG AGGCCGCACCATGCTGCCCATTCGCTGGATGCCGCCCGAGAGCATCCTGTACCGTAAGTTCACCACCGAGAGCGACGTGTGGAGCTTCGG CGTGGTGCTCTGGGAGATCTTCACCTACGGCAAGCAGCCCTGGTACCAGCTCTCCAACACGGAGGCAATCGACTGCATCACGCAGGGACG TGAGTTGGAGCGGCCACGTGCCTGCCCACCAGAGGTCTACGCCATCATGCGGGGCTGCTGGCAGCGGGAGCCCCAGCAACGCCACAGCAT CAAGGATGTGCACGCCCGGCTGCAAGCCCTGGCCCAGGCACCTCCTGTCTACCTGGATGTCCTGGGCTAGGGGGCCGGCCCAGGGGCTGG GAGTGGTTAGCCGGAATACTGGGGCCTGCCCTCAGCATCCCCCATAGCTCCCAGCAGCCCCAGGGTGATCTCAAAGTATCTAATTCACCC >In-frame_ARHGEF25_ENST00000333972_chr12_58008800_+_NTRK1_ENST00000368196_chr1_156841415_+_2978nt CTCGACCCTGAAACTTGGAGCAGGGTGGGGGTTCAGTATGAAGCCCCCGGACCGCCCCGCCCCTGGCCGCACTGACCGGATACTGGGGGT CATGGGGGGCATGCTGCGCGCATGCGCCCTCCCTGGGCAGGAGGGGCCCCCAAGGAGAAGCCCTCTAGGGTTGGTGGGTACCGAGCCAGA GTCTGAACGTACGGAGGGAGATCACAGAAGGGATCGCGAACATGAGGTCCTCGCCGGGGCTCTGCAGCCCGAATCCTATTCCATTGCGGG CAGTGAGGGGAGTATATCGGCTTCTGCTGCCTCCGGTCTGGCTGCCCCCTCTGGCCCCAGCTCTGGCCTCAGCTCTGGCCCCTGTTCCCC AGGCCCCCCAGGGCCCGTCAGTGGCCTGAGGAGATGGTTGGATCATTCCAAACATTGTCTCAGTGTGGAAACTGAGGCAGACAGTGGTCA GGCAGGACCATATGAGAACTGGATGTTGGAGCCAGCTCTAGCCACAGGAGAGGAGCTGCCGGAACTGACCTTGCTGACCACACTGTTGGA GGGCCCTGGAGATAAGACGCAGCCACCTGAAGAGGAGACTTTGTCCCAAGCCCCTGAGAGTGAGGAGGAACAGAAGAAGAAGGCTCTGGA AAGGAGTATGTATGTCCTGAGTGAACTGGTAGAAACAGAGAAAATGTACGTGGACGACTTGGGGCAGATTGTGGAGGGTTATATGGCCAC CATGGCTGCTCAGGGGGTCCCCGAGAGTCTTCGAGGCCGTGACAGGATTGTGTTTGGGAATATCCAGCAAATCTATGAGTGGCACCGAGA CTATTTCTTGCAAGAGCTACAACGGTGTCTGAAAGATCCTGATTGGCTGGCTCAGCTATTCATCAAACACGAGCGCCGGCTGCATATGTA TGTGGTGTACTGTCAGAATAAGCCCAAGTCAGAGCATGTGGTGTCAGAGTTTGGGGACAGCTACTTTGAGGAGCTCCGGCAGCAGCTGGG GCACCGCCTGCAGCTGAACGACCTCCTCATCAAACCTGTGCAGCGGATCATGAAATACCAGCTGCTGCTCAAGGATTTTCTCAAGTATTA CAATAGAGCTGGGATGGATACTGCAGACCTAGAGAAATCTGGGGGTCTGCCATCCCTGGGGCTGACCCTGGCCAATGTCACCAGTGACCT CAACAGGAAGAACGTGACGTGCTGGGCAGAGAACGATGTGGGCCGGGCAGAGGTCTCTGTTCAGGTCAACGTCTCCTTCCCGGCCAGTGT GCAGCTGCACACGGCGGTGGAGATGCACCACTGGTGCATCCCCTTCTCTGTGGATGGGCAGCCGGCACCGTCTCTGCGCTGGCTCTTCAA TGGCTCCGTGCTCAATGAGACCAGCTTCATCTTCACTGAGTTCCTGGAGCCGGCAGCCAATGAGACCGTGCGGCACGGGTGTCTGCGCCT CAACCAGCCCACCCACGTCAACAACGGCAACTACACGCTGCTGGCTGCCAACCCCTTCGGCCAGGCCTCCGCCTCCATCATGGCTGCCTT CATGGACAACCCTTTCGAGTTCAACCCCGAGGACCCCATCCCTGACACTAACAGCACATCTGGAGACCCGGTGGAGAAGAAGGACGAAAC ACCTTTTGGGGTCTCGGTGGCTGTGGGCCTGGCCGTCTTTGCCTGCCTCTTCCTTTCTACGCTGCTCCTTGTGCTCAACAAATGTGGACG GAGAAACAAGTTTGGGATCAACCGCCCGGCTGTGCTGGCTCCAGAGGATGGGCTGGCCATGTCCCTGCATTTCATGACATTGGGTGGCAG CTCCCTGTCCCCCACCGAGGGCAAAGGCTCTGGGCTCCAAGGCCACATCATCGAGAACCCACAATACTTCAGTGATGCCTGTGTTCACCA CATCAAGCGCCGGGACATCGTGCTCAAGTGGGAGCTGGGGGAGGGCGCCTTTGGGAAGGTCTTCCTTGCTGAGTGCCACAACCTCCTGCC TGAGCAGGACAAGATGCTGGTGGCTGTCAAGGCACTGAAGGAGGCGTCCGAGAGTGCTCGGCAGGACTTCCAGCGTGAGGCTGAGCTGCT CACCATGCTGCAGCACCAGCACATCGTGCGCTTCTTCGGCGTCTGCACCGAGGGCCGCCCCCTGCTCATGGTCTTTGAGTATATGCGGCA CGGGGACCTCAACCGCTTCCTCCGATCCCATGGACCTGATGCCAAGCTGCTGGCTGGTGGGGAGGATGTGGCTCCAGGCCCCCTGGGTCT GGGGCAGCTGCTGGCCGTGGCTAGCCAGGTCGCTGCGGGGATGGTGTACCTGGCGGGTCTGCATTTTGTGCACCGGGACCTGGCCACACG CAACTGTCTAGTGGGCCAGGGACTGGTGGTCAAGATTGGTGATTTTGGCATGAGCAGGGATATCTACAGCACCGACTATTACCGTGTGGG AGGCCGCACCATGCTGCCCATTCGCTGGATGCCGCCCGAGAGCATCCTGTACCGTAAGTTCACCACCGAGAGCGACGTGTGGAGCTTCGG CGTGGTGCTCTGGGAGATCTTCACCTACGGCAAGCAGCCCTGGTACCAGCTCTCCAACACGGAGGCAATCGACTGCATCACGCAGGGACG TGAGTTGGAGCGGCCACGTGCCTGCCCACCAGAGGTCTACGCCATCATGCGGGGCTGCTGGCAGCGGGAGCCCCAGCAACGCCACAGCAT CAAGGATGTGCACGCCCGGCTGCAAGCCCTGGCCCAGGCACCTCCTGTCTACCTGGATGTCCTGGGCTAGGGGGCCGGCCCAGGGGCTGG GAGTGGTTAGCCGGAATACTGGGGCCTGCCCTCAGCATCCCCCATAGCTCCCAGCAGCCCCAGGGTGATCTCAAAGTATCTAATTCACCC TCAGCATGTGGGAAGGGACAGGTGGGGGCTGGGAGTAGAGGATGTTCCTGCTTCTCTAGGCAAGGTCCCGTCATAGCAATTATATTTATT >In-frame_ARHGEF25_ENST00000333972_chr12_58008800_+_NTRK1_ENST00000524377_chr1_156841415_+_2788nt CTCGACCCTGAAACTTGGAGCAGGGTGGGGGTTCAGTATGAAGCCCCCGGACCGCCCCGCCCCTGGCCGCACTGACCGGATACTGGGGGT CATGGGGGGCATGCTGCGCGCATGCGCCCTCCCTGGGCAGGAGGGGCCCCCAAGGAGAAGCCCTCTAGGGTTGGTGGGTACCGAGCCAGA GTCTGAACGTACGGAGGGAGATCACAGAAGGGATCGCGAACATGAGGTCCTCGCCGGGGCTCTGCAGCCCGAATCCTATTCCATTGCGGG CAGTGAGGGGAGTATATCGGCTTCTGCTGCCTCCGGTCTGGCTGCCCCCTCTGGCCCCAGCTCTGGCCTCAGCTCTGGCCCCTGTTCCCC AGGCCCCCCAGGGCCCGTCAGTGGCCTGAGGAGATGGTTGGATCATTCCAAACATTGTCTCAGTGTGGAAACTGAGGCAGACAGTGGTCA GGCAGGACCATATGAGAACTGGATGTTGGAGCCAGCTCTAGCCACAGGAGAGGAGCTGCCGGAACTGACCTTGCTGACCACACTGTTGGA GGGCCCTGGAGATAAGACGCAGCCACCTGAAGAGGAGACTTTGTCCCAAGCCCCTGAGAGTGAGGAGGAACAGAAGAAGAAGGCTCTGGA AAGGAGTATGTATGTCCTGAGTGAACTGGTAGAAACAGAGAAAATGTACGTGGACGACTTGGGGCAGATTGTGGAGGGTTATATGGCCAC CATGGCTGCTCAGGGGGTCCCCGAGAGTCTTCGAGGCCGTGACAGGATTGTGTTTGGGAATATCCAGCAAATCTATGAGTGGCACCGAGA CTATTTCTTGCAAGAGCTACAACGGTGTCTGAAAGATCCTGATTGGCTGGCTCAGCTATTCATCAAACACGAGCGCCGGCTGCATATGTA TGTGGTGTACTGTCAGAATAAGCCCAAGTCAGAGCATGTGGTGTCAGAGTTTGGGGACAGCTACTTTGAGGAGCTCCGGCAGCAGCTGGG GCACCGCCTGCAGCTGAACGACCTCCTCATCAAACCTGTGCAGCGGATCATGAAATACCAGCTGCTGCTCAAGGATTTTCTCAAGTATTA CAATAGAGCTGGGATGGATACTGCAGACCTAGAGAAATCTGGGGGTCTGCCATCCCTGGGGCTGACCCTGGCCAATGTCACCAGTGACCT CAACAGGAAGAACGTGACGTGCTGGGCAGAGAACGATGTGGGCCGGGCAGAGGTCTCTGTTCAGGTCAACGTCTCCTTCCCGGCCAGTGT GCAGCTGCACACGGCGGTGGAGATGCACCACTGGTGCATCCCCTTCTCTGTGGATGGGCAGCCGGCACCGTCTCTGCGCTGGCTCTTCAA TGGCTCCGTGCTCAATGAGACCAGCTTCATCTTCACTGAGTTCCTGGAGCCGGCAGCCAATGAGACCGTGCGGCACGGGTGTCTGCGCCT CAACCAGCCCACCCACGTCAACAACGGCAACTACACGCTGCTGGCTGCCAACCCCTTCGGCCAGGCCTCCGCCTCCATCATGGCTGCCTT CATGGACAACCCTTTCGAGTTCAACCCCGAGGACCCCATCCCTGTCTCCTTCTCGCCGGTGGACACTAACAGCACATCTGGAGACCCGGT GGAGAAGAAGGACGAAACACCTTTTGGGGTCTCGGTGGCTGTGGGCCTGGCCGTCTTTGCCTGCCTCTTCCTTTCTACGCTGCTCCTTGT GCTCAACAAATGTGGACGGAGAAACAAGTTTGGGATCAACCGCCCGGCTGTGCTGGCTCCAGAGGATGGGCTGGCCATGTCCCTGCATTT CATGACATTGGGTGGCAGCTCCCTGTCCCCCACCGAGGGCAAAGGCTCTGGGCTCCAAGGCCACATCATCGAGAACCCACAATACTTCAG TGATGCCTGTGTTCACCACATCAAGCGCCGGGACATCGTGCTCAAGTGGGAGCTGGGGGAGGGCGCCTTTGGGAAGGTCTTCCTTGCTGA GTGCCACAACCTCCTGCCTGAGCAGGACAAGATGCTGGTGGCTGTCAAGGCACTGAAGGAGGCGTCCGAGAGTGCTCGGCAGGACTTCCA GCGTGAGGCTGAGCTGCTCACCATGCTGCAGCACCAGCACATCGTGCGCTTCTTCGGCGTCTGCACCGAGGGCCGCCCCCTGCTCATGGT CTTTGAGTATATGCGGCACGGGGACCTCAACCGCTTCCTCCGATCCCATGGACCTGATGCCAAGCTGCTGGCTGGTGGGGAGGATGTGGC TCCAGGCCCCCTGGGTCTGGGGCAGCTGCTGGCCGTGGCTAGCCAGGTCGCTGCGGGGATGGTGTACCTGGCGGGTCTGCATTTTGTGCA CCGGGACCTGGCCACACGCAACTGTCTAGTGGGCCAGGGACTGGTGGTCAAGATTGGTGATTTTGGCATGAGCAGGGATATCTACAGCAC CGACTATTACCGTGTGGGAGGCCGCACCATGCTGCCCATTCGCTGGATGCCGCCCGAGAGCATCCTGTACCGTAAGTTCACCACCGAGAG CGACGTGTGGAGCTTCGGCGTGGTGCTCTGGGAGATCTTCACCTACGGCAAGCAGCCCTGGTACCAGCTCTCCAACACGGAGGCAATCGA CTGCATCACGCAGGGACGTGAGTTGGAGCGGCCACGTGCCTGCCCACCAGAGGTCTACGCCATCATGCGGGGCTGCTGGCAGCGGGAGCC >In-frame_ARHGEF25_ENST00000333972_chr12_58008800_+_NTRK1_ENST00000358660_chr1_156841415_+_2848nt CTCGACCCTGAAACTTGGAGCAGGGTGGGGGTTCAGTATGAAGCCCCCGGACCGCCCCGCCCCTGGCCGCACTGACCGGATACTGGGGGT CATGGGGGGCATGCTGCGCGCATGCGCCCTCCCTGGGCAGGAGGGGCCCCCAAGGAGAAGCCCTCTAGGGTTGGTGGGTACCGAGCCAGA GTCTGAACGTACGGAGGGAGATCACAGAAGGGATCGCGAACATGAGGTCCTCGCCGGGGCTCTGCAGCCCGAATCCTATTCCATTGCGGG CAGTGAGGGGAGTATATCGGCTTCTGCTGCCTCCGGTCTGGCTGCCCCCTCTGGCCCCAGCTCTGGCCTCAGCTCTGGCCCCTGTTCCCC AGGCCCCCCAGGGCCCGTCAGTGGCCTGAGGAGATGGTTGGATCATTCCAAACATTGTCTCAGTGTGGAAACTGAGGCAGACAGTGGTCA GGCAGGACCATATGAGAACTGGATGTTGGAGCCAGCTCTAGCCACAGGAGAGGAGCTGCCGGAACTGACCTTGCTGACCACACTGTTGGA GGGCCCTGGAGATAAGACGCAGCCACCTGAAGAGGAGACTTTGTCCCAAGCCCCTGAGAGTGAGGAGGAACAGAAGAAGAAGGCTCTGGA AAGGAGTATGTATGTCCTGAGTGAACTGGTAGAAACAGAGAAAATGTACGTGGACGACTTGGGGCAGATTGTGGAGGGTTATATGGCCAC CATGGCTGCTCAGGGGGTCCCCGAGAGTCTTCGAGGCCGTGACAGGATTGTGTTTGGGAATATCCAGCAAATCTATGAGTGGCACCGAGA CTATTTCTTGCAAGAGCTACAACGGTGTCTGAAAGATCCTGATTGGCTGGCTCAGCTATTCATCAAACACGAGCGCCGGCTGCATATGTA TGTGGTGTACTGTCAGAATAAGCCCAAGTCAGAGCATGTGGTGTCAGAGTTTGGGGACAGCTACTTTGAGGAGCTCCGGCAGCAGCTGGG GCACCGCCTGCAGCTGAACGACCTCCTCATCAAACCTGTGCAGCGGATCATGAAATACCAGCTGCTGCTCAAGGATTTTCTCAAGTATTA CAATAGAGCTGGGATGGATACTGCAGACCTAGAGAAATCTGGGGGTCTGCCATCCCTGGGGCTGACCCTGGCCAATGTCACCAGTGACCT CAACAGGAAGAACGTGACGTGCTGGGCAGAGAACGATGTGGGCCGGGCAGAGGTCTCTGTTCAGGTCAACGTCTCCTTCCCGGCCAGTGT GCAGCTGCACACGGCGGTGGAGATGCACCACTGGTGCATCCCCTTCTCTGTGGATGGGCAGCCGGCACCGTCTCTGCGCTGGCTCTTCAA TGGCTCCGTGCTCAATGAGACCAGCTTCATCTTCACTGAGTTCCTGGAGCCGGCAGCCAATGAGACCGTGCGGCACGGGTGTCTGCGCCT CAACCAGCCCACCCACGTCAACAACGGCAACTACACGCTGCTGGCTGCCAACCCCTTCGGCCAGGCCTCCGCCTCCATCATGGCTGCCTT CATGGACAACCCTTTCGAGTTCAACCCCGAGGACCCCATCCCTGACACTAACAGCACATCTGGAGACCCGGTGGAGAAGAAGGACGAAAC ACCTTTTGGGGTCTCGGTGGCTGTGGGCCTGGCCGTCTTTGCCTGCCTCTTCCTTTCTACGCTGCTCCTTGTGCTCAACAAATGTGGACG GAGAAACAAGTTTGGGATCAACCGCCCGGCTGTGCTGGCTCCAGAGGATGGGCTGGCCATGTCCCTGCATTTCATGACATTGGGTGGCAG CTCCCTGTCCCCCACCGAGGGCAAAGGCTCTGGGCTCCAAGGCCACATCATCGAGAACCCACAATACTTCAGTGATGCCTCCCCCTCAGG TGTTCACCACATCAAGCGCCGGGACATCGTGCTCAAGTGGGAGCTGGGGGAGGGCGCCTTTGGGAAGGTCTTCCTTGCTGAGTGCCACAA CCTCCTGCCTGAGCAGGACAAGATGCTGGTGGCTGTCAAGGCACTGAAGGAGGCGTCCGAGAGTGCTCGGCAGGACTTCCAGCGTGAGGC TGAGCTGCTCACCATGCTGCAGCACCAGCACATCGTGCGCTTCTTCGGCGTCTGCACCGAGGGCCGCCCCCTGCTCATGGTCTTTGAGTA TATGCGGCACGGGGACCTCAACCGCTTCCTCCGATCCCATGGACCTGATGCCAAGCTGCTGGCTGGTGGGGAGGATGTGGCTCCAGGCCC CCTGGGTCTGGGGCAGCTGCTGGCCGTGGCTAGCCAGGTCGCTGCGGGGATGGTGTACCTGGCGGGTCTGCATTTTGTGCACCGGGACCT GGCCACACGCAACTGTCTAGTGGGCCAGGGACTGGTGGTCAAGATTGGTGATTTTGGCATGAGCAGGGATATCTACAGCACCGACTATTA CCGTGTGGGAGGCCGCACCATGCTGCCCATTCGCTGGATGCCGCCCGAGAGCATCCTGTACCGTAAGTTCACCACCGAGAGCGACGTGTG GAGCTTCGGCGTGGTGCTCTGGGAGATCTTCACCTACGGCAAGCAGCCCTGGTACCAGCTCTCCAACACGGAGGCAATCGACTGCATCAC GCAGGGACGTGAGTTGGAGCGGCCACGTGCCTGCCCACCAGAGGTCTACGCCATCATGCGGGGCTGCTGGCAGCGGGAGCCCCAGCAACG CCACAGCATCAAGGATGTGCACGCCCGGCTGCAAGCCCTGGCCCAGGCACCTCCTGTCTACCTGGATGTCCTGGGCTAGGGGGCCGGCCC >In-frame_ARHGEF25_ENST00000286494_chr12_58008800_+_NTRK1_ENST00000392302_chr1_156841415_+_3228nt ATTCAGCTCTCCGCTCCGCTGGGACCCGCACAGCGCCAGTGGCTCGGGGGTCGGCCCTCGCCTCCTCCCCGGCCCGGGCCTAGAGCCACC CCTAACCAGAGGCCGGAGACAGCTGGAGCGGCTGCCGCATCCCGGCCCAGCCTCCCCTACCATCCCTCCCCCTTCCACTGGACATCTGGA CCCTAGGCCCCCGCACCGACAGGGTTCCGGAAACCCTCCCCGCCCAGCCCGGCGGCCGGGCCCCGCGCCTCTCTCTCTCTAGAGCCCCCA GCCCTCCTCAAGACTAGACTTCCGCCTACCCCTGGACACCTCCTCCCGGTCCCCTCCCTCCCCCCCTCCCACAGCCTGGACCGGGGTAGG AGGGAGGGGGGGTGTGCGCCCGGCGCCGTCCCCGCCCCGCCCCCCGTGATTCCCCCTGCATGGCCGGCCCGGGTGGGGGGCGCGGGGGGG CCCGGGCGCCATGCGGGGGGGGCACAAAGGGGGTCGCTGTGCCTGTCCCCGTGTGATCCGAAAAGTGCTGGCAAAATGCGGCTGCTGCTT CGCCCGGGGGGGACGTGAATCCTATTCCATTGCGGGCAGTGAGGGGAGTATATCGGCTTCTGCTGCCTCCGGTCTGGCTGCCCCCTCTGG CCCCAGCTCTGGCCTCAGCTCTGGCCCCTGTTCCCCAGGCCCCCCAGGGCCCGTCAGTGGCCTGAGGAGATGGTTGGATCATTCCAAACA TTGTCTCAGTGTGGAAACTGAGGCAGACAGTGGTCAGGCAGGACCATATGAGAACTGGATGTTGGAGCCAGCTCTAGCCACAGGAGAGGA GCTGCCGGAACTGACCTTGCTGACCACACTGTTGGAGGGCCCTGGAGATAAGACGCAGCCACCTGAAGAGGAGACTTTGTCCCAAGCCCC TGAGAGTGAGGAGGAACAGAAGAAGAAGGCTCTGGAAAGGAGTATGTATGTCCTGAGTGAACTGGTAGAAACAGAGAAAATGTACGTGGA CGACTTGGGGCAGATTGTGGAGGGTTATATGGCCACCATGGCTGCTCAGGGGGTCCCCGAGAGTCTTCGAGGCCGTGACAGGATTGTGTT TGGGAATATCCAGCAAATCTATGAGTGGCACCGAGACTATTTCTTGCAAGAGCTACAACGGTGTCTGAAAGATCCTGATTGGCTGGCTCA GCTATTCATCAAACACGAGCGCCGGCTGCATATGTATGTGGTGTACTGTCAGAATAAGCCCAAGTCAGAGCATGTGGTGTCAGAGTTTGG GGACAGCTACTTTGAGGAGCTCCGGCAGCAGCTGGGGCACCGCCTGCAGCTGAACGACCTCCTCATCAAACCTGTGCAGCGGATCATGAA ATACCAGCTGCTGCTCAAGGATTTTCTCAAGTATTACAATAGAGCTGGGATGGATACTGCAGACCTAGAGAAATCTGGGGGTCTGCCATC CCTGGGGCTGACCCTGGCCAATGTCACCAGTGACCTCAACAGGAAGAACGTGACGTGCTGGGCAGAGAACGATGTGGGCCGGGCAGAGGT CTCTGTTCAGGTCAACGTCTCCTTCCCGGCCAGTGTGCAGCTGCACACGGCGGTGGAGATGCACCACTGGTGCATCCCCTTCTCTGTGGA TGGGCAGCCGGCACCGTCTCTGCGCTGGCTCTTCAATGGCTCCGTGCTCAATGAGACCAGCTTCATCTTCACTGAGTTCCTGGAGCCGGC AGCCAATGAGACCGTGCGGCACGGGTGTCTGCGCCTCAACCAGCCCACCCACGTCAACAACGGCAACTACACGCTGCTGGCTGCCAACCC CTTCGGCCAGGCCTCCGCCTCCATCATGGCTGCCTTCATGGACAACCCTTTCGAGTTCAACCCCGAGGACCCCATCCCTGACACTAACAG CACATCTGGAGACCCGGTGGAGAAGAAGGACGAAACACCTTTTGGGGTCTCGGTGGCTGTGGGCCTGGCCGTCTTTGCCTGCCTCTTCCT TTCTACGCTGCTCCTTGTGCTCAACAAATGTGGACGGAGAAACAAGTTTGGGATCAACCGCCCGGCTGTGCTGGCTCCAGAGGATGGGCT GGCCATGTCCCTGCATTTCATGACATTGGGTGGCAGCTCCCTGTCCCCCACCGAGGGCAAAGGCTCTGGGCTCCAAGGCCACATCATCGA GAACCCACAATACTTCAGTGATGCCTGTGTTCACCACATCAAGCGCCGGGACATCGTGCTCAAGTGGGAGCTGGGGGAGGGCGCCTTTGG GAAGGTCTTCCTTGCTGAGTGCCACAACCTCCTGCCTGAGCAGGACAAGATGCTGGTGGCTGTCAAGGCACTGAAGGAGGCGTCCGAGAG TGCTCGGCAGGACTTCCAGCGTGAGGCTGAGCTGCTCACCATGCTGCAGCACCAGCACATCGTGCGCTTCTTCGGCGTCTGCACCGAGGG CCGCCCCCTGCTCATGGTCTTTGAGTATATGCGGCACGGGGACCTCAACCGCTTCCTCCGATCCCATGGACCTGATGCCAAGCTGCTGGC TGGTGGGGAGGATGTGGCTCCAGGCCCCCTGGGTCTGGGGCAGCTGCTGGCCGTGGCTAGCCAGGTCGCTGCGGGGATGGTGTACCTGGC GGGTCTGCATTTTGTGCACCGGGACCTGGCCACACGCAACTGTCTAGTGGGCCAGGGACTGGTGGTCAAGATTGGTGATTTTGGCATGAG CAGGGATATCTACAGCACCGACTATTACCGTGTGGGAGGCCGCACCATGCTGCCCATTCGCTGGATGCCGCCCGAGAGCATCCTGTACCG TAAGTTCACCACCGAGAGCGACGTGTGGAGCTTCGGCGTGGTGCTCTGGGAGATCTTCACCTACGGCAAGCAGCCCTGGTACCAGCTCTC CAACACGGAGGCAATCGACTGCATCACGCAGGGACGTGAGTTGGAGCGGCCACGTGCCTGCCCACCAGAGGTCTACGCCATCATGCGGGG CTGCTGGCAGCGGGAGCCCCAGCAACGCCACAGCATCAAGGATGTGCACGCCCGGCTGCAAGCCCTGGCCCAGGCACCTCCTGTCTACCT GGATGTCCTGGGCTAGGGGGCCGGCCCAGGGGCTGGGAGTGGTTAGCCGGAATACTGGGGCCTGCCCTCAGCATCCCCCATAGCTCCCAG >In-frame_ARHGEF25_ENST00000286494_chr12_58008800_+_NTRK1_ENST00000368196_chr1_156841415_+_3284nt ATTCAGCTCTCCGCTCCGCTGGGACCCGCACAGCGCCAGTGGCTCGGGGGTCGGCCCTCGCCTCCTCCCCGGCCCGGGCCTAGAGCCACC CCTAACCAGAGGCCGGAGACAGCTGGAGCGGCTGCCGCATCCCGGCCCAGCCTCCCCTACCATCCCTCCCCCTTCCACTGGACATCTGGA CCCTAGGCCCCCGCACCGACAGGGTTCCGGAAACCCTCCCCGCCCAGCCCGGCGGCCGGGCCCCGCGCCTCTCTCTCTCTAGAGCCCCCA GCCCTCCTCAAGACTAGACTTCCGCCTACCCCTGGACACCTCCTCCCGGTCCCCTCCCTCCCCCCCTCCCACAGCCTGGACCGGGGTAGG AGGGAGGGGGGGTGTGCGCCCGGCGCCGTCCCCGCCCCGCCCCCCGTGATTCCCCCTGCATGGCCGGCCCGGGTGGGGGGCGCGGGGGGG CCCGGGCGCCATGCGGGGGGGGCACAAAGGGGGTCGCTGTGCCTGTCCCCGTGTGATCCGAAAAGTGCTGGCAAAATGCGGCTGCTGCTT CGCCCGGGGGGGACGTGAATCCTATTCCATTGCGGGCAGTGAGGGGAGTATATCGGCTTCTGCTGCCTCCGGTCTGGCTGCCCCCTCTGG CCCCAGCTCTGGCCTCAGCTCTGGCCCCTGTTCCCCAGGCCCCCCAGGGCCCGTCAGTGGCCTGAGGAGATGGTTGGATCATTCCAAACA TTGTCTCAGTGTGGAAACTGAGGCAGACAGTGGTCAGGCAGGACCATATGAGAACTGGATGTTGGAGCCAGCTCTAGCCACAGGAGAGGA GCTGCCGGAACTGACCTTGCTGACCACACTGTTGGAGGGCCCTGGAGATAAGACGCAGCCACCTGAAGAGGAGACTTTGTCCCAAGCCCC TGAGAGTGAGGAGGAACAGAAGAAGAAGGCTCTGGAAAGGAGTATGTATGTCCTGAGTGAACTGGTAGAAACAGAGAAAATGTACGTGGA CGACTTGGGGCAGATTGTGGAGGGTTATATGGCCACCATGGCTGCTCAGGGGGTCCCCGAGAGTCTTCGAGGCCGTGACAGGATTGTGTT TGGGAATATCCAGCAAATCTATGAGTGGCACCGAGACTATTTCTTGCAAGAGCTACAACGGTGTCTGAAAGATCCTGATTGGCTGGCTCA GCTATTCATCAAACACGAGCGCCGGCTGCATATGTATGTGGTGTACTGTCAGAATAAGCCCAAGTCAGAGCATGTGGTGTCAGAGTTTGG GGACAGCTACTTTGAGGAGCTCCGGCAGCAGCTGGGGCACCGCCTGCAGCTGAACGACCTCCTCATCAAACCTGTGCAGCGGATCATGAA ATACCAGCTGCTGCTCAAGGATTTTCTCAAGTATTACAATAGAGCTGGGATGGATACTGCAGACCTAGAGAAATCTGGGGGTCTGCCATC CCTGGGGCTGACCCTGGCCAATGTCACCAGTGACCTCAACAGGAAGAACGTGACGTGCTGGGCAGAGAACGATGTGGGCCGGGCAGAGGT CTCTGTTCAGGTCAACGTCTCCTTCCCGGCCAGTGTGCAGCTGCACACGGCGGTGGAGATGCACCACTGGTGCATCCCCTTCTCTGTGGA TGGGCAGCCGGCACCGTCTCTGCGCTGGCTCTTCAATGGCTCCGTGCTCAATGAGACCAGCTTCATCTTCACTGAGTTCCTGGAGCCGGC AGCCAATGAGACCGTGCGGCACGGGTGTCTGCGCCTCAACCAGCCCACCCACGTCAACAACGGCAACTACACGCTGCTGGCTGCCAACCC CTTCGGCCAGGCCTCCGCCTCCATCATGGCTGCCTTCATGGACAACCCTTTCGAGTTCAACCCCGAGGACCCCATCCCTGACACTAACAG CACATCTGGAGACCCGGTGGAGAAGAAGGACGAAACACCTTTTGGGGTCTCGGTGGCTGTGGGCCTGGCCGTCTTTGCCTGCCTCTTCCT TTCTACGCTGCTCCTTGTGCTCAACAAATGTGGACGGAGAAACAAGTTTGGGATCAACCGCCCGGCTGTGCTGGCTCCAGAGGATGGGCT GGCCATGTCCCTGCATTTCATGACATTGGGTGGCAGCTCCCTGTCCCCCACCGAGGGCAAAGGCTCTGGGCTCCAAGGCCACATCATCGA GAACCCACAATACTTCAGTGATGCCTGTGTTCACCACATCAAGCGCCGGGACATCGTGCTCAAGTGGGAGCTGGGGGAGGGCGCCTTTGG GAAGGTCTTCCTTGCTGAGTGCCACAACCTCCTGCCTGAGCAGGACAAGATGCTGGTGGCTGTCAAGGCACTGAAGGAGGCGTCCGAGAG TGCTCGGCAGGACTTCCAGCGTGAGGCTGAGCTGCTCACCATGCTGCAGCACCAGCACATCGTGCGCTTCTTCGGCGTCTGCACCGAGGG CCGCCCCCTGCTCATGGTCTTTGAGTATATGCGGCACGGGGACCTCAACCGCTTCCTCCGATCCCATGGACCTGATGCCAAGCTGCTGGC TGGTGGGGAGGATGTGGCTCCAGGCCCCCTGGGTCTGGGGCAGCTGCTGGCCGTGGCTAGCCAGGTCGCTGCGGGGATGGTGTACCTGGC GGGTCTGCATTTTGTGCACCGGGACCTGGCCACACGCAACTGTCTAGTGGGCCAGGGACTGGTGGTCAAGATTGGTGATTTTGGCATGAG CAGGGATATCTACAGCACCGACTATTACCGTGTGGGAGGCCGCACCATGCTGCCCATTCGCTGGATGCCGCCCGAGAGCATCCTGTACCG TAAGTTCACCACCGAGAGCGACGTGTGGAGCTTCGGCGTGGTGCTCTGGGAGATCTTCACCTACGGCAAGCAGCCCTGGTACCAGCTCTC CAACACGGAGGCAATCGACTGCATCACGCAGGGACGTGAGTTGGAGCGGCCACGTGCCTGCCCACCAGAGGTCTACGCCATCATGCGGGG CTGCTGGCAGCGGGAGCCCCAGCAACGCCACAGCATCAAGGATGTGCACGCCCGGCTGCAAGCCCTGGCCCAGGCACCTCCTGTCTACCT GGATGTCCTGGGCTAGGGGGCCGGCCCAGGGGCTGGGAGTGGTTAGCCGGAATACTGGGGCCTGCCCTCAGCATCCCCCATAGCTCCCAG CAGCCCCAGGGTGATCTCAAAGTATCTAATTCACCCTCAGCATGTGGGAAGGGACAGGTGGGGGCTGGGAGTAGAGGATGTTCCTGCTTC >In-frame_ARHGEF25_ENST00000286494_chr12_58008800_+_NTRK1_ENST00000524377_chr1_156841415_+_3094nt ATTCAGCTCTCCGCTCCGCTGGGACCCGCACAGCGCCAGTGGCTCGGGGGTCGGCCCTCGCCTCCTCCCCGGCCCGGGCCTAGAGCCACC CCTAACCAGAGGCCGGAGACAGCTGGAGCGGCTGCCGCATCCCGGCCCAGCCTCCCCTACCATCCCTCCCCCTTCCACTGGACATCTGGA CCCTAGGCCCCCGCACCGACAGGGTTCCGGAAACCCTCCCCGCCCAGCCCGGCGGCCGGGCCCCGCGCCTCTCTCTCTCTAGAGCCCCCA GCCCTCCTCAAGACTAGACTTCCGCCTACCCCTGGACACCTCCTCCCGGTCCCCTCCCTCCCCCCCTCCCACAGCCTGGACCGGGGTAGG AGGGAGGGGGGGTGTGCGCCCGGCGCCGTCCCCGCCCCGCCCCCCGTGATTCCCCCTGCATGGCCGGCCCGGGTGGGGGGCGCGGGGGGG CCCGGGCGCCATGCGGGGGGGGCACAAAGGGGGTCGCTGTGCCTGTCCCCGTGTGATCCGAAAAGTGCTGGCAAAATGCGGCTGCTGCTT CGCCCGGGGGGGACGTGAATCCTATTCCATTGCGGGCAGTGAGGGGAGTATATCGGCTTCTGCTGCCTCCGGTCTGGCTGCCCCCTCTGG CCCCAGCTCTGGCCTCAGCTCTGGCCCCTGTTCCCCAGGCCCCCCAGGGCCCGTCAGTGGCCTGAGGAGATGGTTGGATCATTCCAAACA TTGTCTCAGTGTGGAAACTGAGGCAGACAGTGGTCAGGCAGGACCATATGAGAACTGGATGTTGGAGCCAGCTCTAGCCACAGGAGAGGA GCTGCCGGAACTGACCTTGCTGACCACACTGTTGGAGGGCCCTGGAGATAAGACGCAGCCACCTGAAGAGGAGACTTTGTCCCAAGCCCC TGAGAGTGAGGAGGAACAGAAGAAGAAGGCTCTGGAAAGGAGTATGTATGTCCTGAGTGAACTGGTAGAAACAGAGAAAATGTACGTGGA CGACTTGGGGCAGATTGTGGAGGGTTATATGGCCACCATGGCTGCTCAGGGGGTCCCCGAGAGTCTTCGAGGCCGTGACAGGATTGTGTT TGGGAATATCCAGCAAATCTATGAGTGGCACCGAGACTATTTCTTGCAAGAGCTACAACGGTGTCTGAAAGATCCTGATTGGCTGGCTCA GCTATTCATCAAACACGAGCGCCGGCTGCATATGTATGTGGTGTACTGTCAGAATAAGCCCAAGTCAGAGCATGTGGTGTCAGAGTTTGG GGACAGCTACTTTGAGGAGCTCCGGCAGCAGCTGGGGCACCGCCTGCAGCTGAACGACCTCCTCATCAAACCTGTGCAGCGGATCATGAA ATACCAGCTGCTGCTCAAGGATTTTCTCAAGTATTACAATAGAGCTGGGATGGATACTGCAGACCTAGAGAAATCTGGGGGTCTGCCATC CCTGGGGCTGACCCTGGCCAATGTCACCAGTGACCTCAACAGGAAGAACGTGACGTGCTGGGCAGAGAACGATGTGGGCCGGGCAGAGGT CTCTGTTCAGGTCAACGTCTCCTTCCCGGCCAGTGTGCAGCTGCACACGGCGGTGGAGATGCACCACTGGTGCATCCCCTTCTCTGTGGA TGGGCAGCCGGCACCGTCTCTGCGCTGGCTCTTCAATGGCTCCGTGCTCAATGAGACCAGCTTCATCTTCACTGAGTTCCTGGAGCCGGC AGCCAATGAGACCGTGCGGCACGGGTGTCTGCGCCTCAACCAGCCCACCCACGTCAACAACGGCAACTACACGCTGCTGGCTGCCAACCC CTTCGGCCAGGCCTCCGCCTCCATCATGGCTGCCTTCATGGACAACCCTTTCGAGTTCAACCCCGAGGACCCCATCCCTGTCTCCTTCTC GCCGGTGGACACTAACAGCACATCTGGAGACCCGGTGGAGAAGAAGGACGAAACACCTTTTGGGGTCTCGGTGGCTGTGGGCCTGGCCGT CTTTGCCTGCCTCTTCCTTTCTACGCTGCTCCTTGTGCTCAACAAATGTGGACGGAGAAACAAGTTTGGGATCAACCGCCCGGCTGTGCT GGCTCCAGAGGATGGGCTGGCCATGTCCCTGCATTTCATGACATTGGGTGGCAGCTCCCTGTCCCCCACCGAGGGCAAAGGCTCTGGGCT CCAAGGCCACATCATCGAGAACCCACAATACTTCAGTGATGCCTGTGTTCACCACATCAAGCGCCGGGACATCGTGCTCAAGTGGGAGCT GGGGGAGGGCGCCTTTGGGAAGGTCTTCCTTGCTGAGTGCCACAACCTCCTGCCTGAGCAGGACAAGATGCTGGTGGCTGTCAAGGCACT GAAGGAGGCGTCCGAGAGTGCTCGGCAGGACTTCCAGCGTGAGGCTGAGCTGCTCACCATGCTGCAGCACCAGCACATCGTGCGCTTCTT CGGCGTCTGCACCGAGGGCCGCCCCCTGCTCATGGTCTTTGAGTATATGCGGCACGGGGACCTCAACCGCTTCCTCCGATCCCATGGACC TGATGCCAAGCTGCTGGCTGGTGGGGAGGATGTGGCTCCAGGCCCCCTGGGTCTGGGGCAGCTGCTGGCCGTGGCTAGCCAGGTCGCTGC GGGGATGGTGTACCTGGCGGGTCTGCATTTTGTGCACCGGGACCTGGCCACACGCAACTGTCTAGTGGGCCAGGGACTGGTGGTCAAGAT TGGTGATTTTGGCATGAGCAGGGATATCTACAGCACCGACTATTACCGTGTGGGAGGCCGCACCATGCTGCCCATTCGCTGGATGCCGCC CGAGAGCATCCTGTACCGTAAGTTCACCACCGAGAGCGACGTGTGGAGCTTCGGCGTGGTGCTCTGGGAGATCTTCACCTACGGCAAGCA GCCCTGGTACCAGCTCTCCAACACGGAGGCAATCGACTGCATCACGCAGGGACGTGAGTTGGAGCGGCCACGTGCCTGCCCACCAGAGGT CTACGCCATCATGCGGGGCTGCTGGCAGCGGGAGCCCCAGCAACGCCACAGCATCAAGGATGTGCACGCCCGGCTGCAAGCCCTGGCCCA >In-frame_ARHGEF25_ENST00000286494_chr12_58008800_+_NTRK1_ENST00000358660_chr1_156841415_+_3154nt ATTCAGCTCTCCGCTCCGCTGGGACCCGCACAGCGCCAGTGGCTCGGGGGTCGGCCCTCGCCTCCTCCCCGGCCCGGGCCTAGAGCCACC CCTAACCAGAGGCCGGAGACAGCTGGAGCGGCTGCCGCATCCCGGCCCAGCCTCCCCTACCATCCCTCCCCCTTCCACTGGACATCTGGA CCCTAGGCCCCCGCACCGACAGGGTTCCGGAAACCCTCCCCGCCCAGCCCGGCGGCCGGGCCCCGCGCCTCTCTCTCTCTAGAGCCCCCA GCCCTCCTCAAGACTAGACTTCCGCCTACCCCTGGACACCTCCTCCCGGTCCCCTCCCTCCCCCCCTCCCACAGCCTGGACCGGGGTAGG AGGGAGGGGGGGTGTGCGCCCGGCGCCGTCCCCGCCCCGCCCCCCGTGATTCCCCCTGCATGGCCGGCCCGGGTGGGGGGCGCGGGGGGG CCCGGGCGCCATGCGGGGGGGGCACAAAGGGGGTCGCTGTGCCTGTCCCCGTGTGATCCGAAAAGTGCTGGCAAAATGCGGCTGCTGCTT CGCCCGGGGGGGACGTGAATCCTATTCCATTGCGGGCAGTGAGGGGAGTATATCGGCTTCTGCTGCCTCCGGTCTGGCTGCCCCCTCTGG CCCCAGCTCTGGCCTCAGCTCTGGCCCCTGTTCCCCAGGCCCCCCAGGGCCCGTCAGTGGCCTGAGGAGATGGTTGGATCATTCCAAACA TTGTCTCAGTGTGGAAACTGAGGCAGACAGTGGTCAGGCAGGACCATATGAGAACTGGATGTTGGAGCCAGCTCTAGCCACAGGAGAGGA GCTGCCGGAACTGACCTTGCTGACCACACTGTTGGAGGGCCCTGGAGATAAGACGCAGCCACCTGAAGAGGAGACTTTGTCCCAAGCCCC TGAGAGTGAGGAGGAACAGAAGAAGAAGGCTCTGGAAAGGAGTATGTATGTCCTGAGTGAACTGGTAGAAACAGAGAAAATGTACGTGGA CGACTTGGGGCAGATTGTGGAGGGTTATATGGCCACCATGGCTGCTCAGGGGGTCCCCGAGAGTCTTCGAGGCCGTGACAGGATTGTGTT TGGGAATATCCAGCAAATCTATGAGTGGCACCGAGACTATTTCTTGCAAGAGCTACAACGGTGTCTGAAAGATCCTGATTGGCTGGCTCA GCTATTCATCAAACACGAGCGCCGGCTGCATATGTATGTGGTGTACTGTCAGAATAAGCCCAAGTCAGAGCATGTGGTGTCAGAGTTTGG GGACAGCTACTTTGAGGAGCTCCGGCAGCAGCTGGGGCACCGCCTGCAGCTGAACGACCTCCTCATCAAACCTGTGCAGCGGATCATGAA ATACCAGCTGCTGCTCAAGGATTTTCTCAAGTATTACAATAGAGCTGGGATGGATACTGCAGACCTAGAGAAATCTGGGGGTCTGCCATC CCTGGGGCTGACCCTGGCCAATGTCACCAGTGACCTCAACAGGAAGAACGTGACGTGCTGGGCAGAGAACGATGTGGGCCGGGCAGAGGT CTCTGTTCAGGTCAACGTCTCCTTCCCGGCCAGTGTGCAGCTGCACACGGCGGTGGAGATGCACCACTGGTGCATCCCCTTCTCTGTGGA TGGGCAGCCGGCACCGTCTCTGCGCTGGCTCTTCAATGGCTCCGTGCTCAATGAGACCAGCTTCATCTTCACTGAGTTCCTGGAGCCGGC AGCCAATGAGACCGTGCGGCACGGGTGTCTGCGCCTCAACCAGCCCACCCACGTCAACAACGGCAACTACACGCTGCTGGCTGCCAACCC CTTCGGCCAGGCCTCCGCCTCCATCATGGCTGCCTTCATGGACAACCCTTTCGAGTTCAACCCCGAGGACCCCATCCCTGACACTAACAG CACATCTGGAGACCCGGTGGAGAAGAAGGACGAAACACCTTTTGGGGTCTCGGTGGCTGTGGGCCTGGCCGTCTTTGCCTGCCTCTTCCT TTCTACGCTGCTCCTTGTGCTCAACAAATGTGGACGGAGAAACAAGTTTGGGATCAACCGCCCGGCTGTGCTGGCTCCAGAGGATGGGCT GGCCATGTCCCTGCATTTCATGACATTGGGTGGCAGCTCCCTGTCCCCCACCGAGGGCAAAGGCTCTGGGCTCCAAGGCCACATCATCGA GAACCCACAATACTTCAGTGATGCCTCCCCCTCAGGTGTTCACCACATCAAGCGCCGGGACATCGTGCTCAAGTGGGAGCTGGGGGAGGG CGCCTTTGGGAAGGTCTTCCTTGCTGAGTGCCACAACCTCCTGCCTGAGCAGGACAAGATGCTGGTGGCTGTCAAGGCACTGAAGGAGGC GTCCGAGAGTGCTCGGCAGGACTTCCAGCGTGAGGCTGAGCTGCTCACCATGCTGCAGCACCAGCACATCGTGCGCTTCTTCGGCGTCTG CACCGAGGGCCGCCCCCTGCTCATGGTCTTTGAGTATATGCGGCACGGGGACCTCAACCGCTTCCTCCGATCCCATGGACCTGATGCCAA GCTGCTGGCTGGTGGGGAGGATGTGGCTCCAGGCCCCCTGGGTCTGGGGCAGCTGCTGGCCGTGGCTAGCCAGGTCGCTGCGGGGATGGT GTACCTGGCGGGTCTGCATTTTGTGCACCGGGACCTGGCCACACGCAACTGTCTAGTGGGCCAGGGACTGGTGGTCAAGATTGGTGATTT TGGCATGAGCAGGGATATCTACAGCACCGACTATTACCGTGTGGGAGGCCGCACCATGCTGCCCATTCGCTGGATGCCGCCCGAGAGCAT CCTGTACCGTAAGTTCACCACCGAGAGCGACGTGTGGAGCTTCGGCGTGGTGCTCTGGGAGATCTTCACCTACGGCAAGCAGCCCTGGTA CCAGCTCTCCAACACGGAGGCAATCGACTGCATCACGCAGGGACGTGAGTTGGAGCGGCCACGTGCCTGCCCACCAGAGGTCTACGCCAT CATGCGGGGCTGCTGGCAGCGGGAGCCCCAGCAACGCCACAGCATCAAGGATGTGCACGCCCGGCTGCAAGCCCTGGCCCAGGCACCTCC TGTCTACCTGGATGTCCTGGGCTAGGGGGCCGGCCCAGGGGCTGGGAGTGGTTAGCCGGAATACTGGGGCCTGCCCTCAGCATCCCCCAT |
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FusionGenePPI for ARHGEF25_NTRK1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| ARHGEF25 | RHOA, CDC42, RAC1, PRKCG, RHOU, CORO2B, GABRB2, RTN4R | NTRK1 | ABL1, NGF, MATK, PLCG1, GRB2, CAV1, NTF3, SQSTM1, SH2B1, SHC1, SH2B2, ARHGAP32, FRS2, NTRK1, RAP1A, SHC3, GIPC1, RGS19, PTPN1, TRAF6, NEDD4, CBL, HSP90AA1, HSPA4, CDC37, NEDD4L, MYC, SGSM3, SORBS1, TNK2, SNX17, SNX27, GAREML, SOS2, PIK3CA, GAREM, PIK3C2B, ARHGEF40, PIK3R1, PIK3R2, SOS1, PIK3CB, PML, UBC, AMFR, CBLB, GAB1, EPN1, PIK3C2A, ANKRD13A, DOCK4, TRIO, LGR5, WRNIP1, RABEP1, PDGFRA, KANK2, RABGEF1, VAV2, TBC1D15, PTPN11, GAK, IRS2, PCDHGC3, EPS15, LRRN3, HUWE1, ACVR1B, MIB1, OFD1, PIBF1, ZNF497, TXN, CAT, FABP3, JUP, DSG1, TGM1, CFL1, LCN1, HIST2H4A, DSP, PFN1, LGALS3BP, HIST1H2BL, LTF, S100A9, IGLL5, TGM3, DSC1, LYZ, DCD, LEKR1, ENO2, PPIA, BTN1A1, XRCC5, XRCC6, HLA-A, GSTP1, ABCB7, PA2G4, PRDX1, HDGF, HSPA4L, TBC1D10B, HP1BP3, KIF26B, SYT4, RHOBTB3, NOTCH3, GAB2, ATAD3A, RBM15B, KCNH2, USP15, PDCD11, RBFOX2, RBM14, RNF31, ADNP, ZC3HAV1, MAP7D1, USP4, JAK1, PTPRS, PDGFRB, HIST1H1C, USP11, PPFIBP1, INTS6, VGF, ARHGEF11, SMPD4, SYNPO2, HNRNPM, SLC27A4, DDX41, EGFR, H1FX, ASAP1, HIST1H1B, RRBP1, EPHA2, KIDINS220, CPT1A, UNC5B, IGF1R, DDR2, AUP1, XPR1, RP9, MARK2, REPS1, EMD, SMARCA4, DDX21, DAB2IP, C7, MSTO1, CDC27, ZNF629, ASAP2, NCAPH2, SRBD1, ATAD3B, TCF12, PLEKHA6, INPPL1, PRPF4B, DPM1, SMARCA1, FIP1L1, DLGAP5, PLEKHH3, TRA2A, ACIN1, DDX10, TAX1BP1, SMARCA5, RABEP2, DDX5, MYO1C, SRSF10, DNAJA2, RET, TRA2B, MYEF2, PNPLA6, SLC12A2, TAF6L, RSL1D1, ARAP3, DDX18, ABL2, KHDRBS1, CERK, SRSF7, SPTLC2, PBXIP1, DNAJA1, IQGAP3, DDX31, ZC3H11A, PLRG1, CNP, FMR1, HIP1R, KIAA1429, CDC5L, ARAP1, ZNF316, SMARCC2, EML5, VANGL2, SLC25A1, UNC5C, SLC16A1, RFC1, ZKSCAN1, CHD1, PTK7, SMARCD2, AP3B1, YTHDC2, AKAP8L, RPL15, CTNND1, PHLDB1, ZNF574, DDX27, TOM1, RASA1, MORC2, MTCH2, IMMT, SMARCC1, ROR2, CAPN2, DNAJC11, SYT11, AP2A1, LBR, MEPCE, NCAPD3, CEP97, QKI, LRRC41, LPCAT2, EPS15L1, LAS1L, TMEM131, CWF19L2, NCAPG2, MAP4K5, CCP110, ARHGEF2, ITGAV, ZC3H18, CWC22, VIM, FAM171A1, TMEM132A, SRSF9, SOGA1, NKRF, RBL1, FMNL3, TOP1, PIGT, RBM15, GBAS, EDC3, WDR5, NOP2, GNL2, SLC25A11, RRP1B, FAM115A, INTS5, SLC25A5, AAK1, HERC5, CCNT1, FERMT2, CDC42BPA, MRPL28, UBAP2, WWP2, SEC24B, HNRNPU, GPD2, FXR2, DHX15, SLC25A22, SSR1, PLXNB2, PROX1, TEX10, USP19, FTSJ3, TMEM59, GTF3C2, PGAM5, CPSF1, KLHL22, TMX3, SIN3A, NOP58, PTCD3, RPRD2, DHX9, PICALM, FARP1, SLC25A6, ERLIN2, SMARCD1, RHOT1, ALDH1B1, SGPL1, USP9X, HNRNPF, KIAA1211, MAPK7, DDX17, GSE1, DVL3, MRPL44, DNAJB6, GTPBP4, HNRNPA0, PLXNA4, SFXN3, NAT10, DDX28, SNW1, MYO6, MRPL24, PRRT4, FAM98A, PURA, DHX29, C1QBP, TRIP4, TBK1, RBM28, ZNF609, POLRMT, PCDHB3, XRN1, HSD17B11, DKC1, DHX30, CDK13, SENP3, LPHN2, GPATCH4, NDUFA9, RASA4, MCCC1, DDX24, RPL14, RPS8, ATG2B, MYO1B, PTPN12, CEBPZ, ILVBL, RALY, KIF14, ZC3H7A, MOV10, MAP4K4, DHX57, RBMX, FXR1, MRPS35, SART1, MARK3, DECR1, CCDC88A, ANKLE2, PRPF31, LARP7, RPL10, PACS1, RPL13, FAM120A, SLC25A13, ADAR, CDK1, HNRNPR, CSNK1E, DLG1, LEMD3, NOL9, IFT122, NCLN, STK11IP, GATAD2B, CHERP, LARP4, MAP3K1, HNRNPUL2, PPIL2, ESYT2, MYH10, RPL8, UQCRC2, NDUFA10, HAX1, HELLS, MED14, RBM42, CHCHD3, RPL7, ABCD3, TUBGCP6, MRPS9, SNRNP200, IGF2BP3, LRCH3, MRPL3, RSBN1L, SAFB, TUBG1, ALDH16A1, ARHGEF12, EPB41L5, AP2A2, SRSF6, HLTF, PTPLAD1, TMPO, AGO2, POP1, RPS9, HDAC6, ILF3, VWA8, ABCB1, SCRIB, GTF3C5, YBX1, RBM4, PTPN9, PRPF8, BRD3, TRIM24, CLASP2, MADD, TCF4, MAP4K3, TSC2, DDX23, RPL7A, RRP12, PRKD2, TRMT1L, EDC4, CSTF3, RPS2, NDUFS2, RPL13A, PTPRR, ATP7A, EXD2, IK, HIP1, MATR3, IGSF3, PTPRF, SPATA5L1, EFTUD2, RPS3A, TUBGCP5, TTN, GIT1, PATL1, NUP160, PDE4B, SUN2, PTPN23, RPS6, DCP1A, CDC73, MEX3A, EIF2AK2, RPL3, PPP1R10, SRP72, ELAVL3, NOM1, RPL18, CEP170, THRAP3, MED17, MRPS7, DDX20, PDPR, SH3PXD2A, DBN1, DAP3, OAS3, STT3B, COPE, MED12, AP3D1, CAPRIN1, PHB2, U2SURP, BSG, TECR, FARSA, HSD17B12, RPL4, HNRNPUL1, PPFIA1, MRPS22, TBL3, GNL3, MTA2, CPSF2, ATP2B1, AP3B2, PPIP5K2, DDX56, ASCC3, FMNL2, SMCHD1, MYBBP1A, SRPK2, RHOT2, SRP68, PUM1, SLC25A3, SRPK1, RPL19, BEND3, SEC61A1, LSG1, NOC3L, TNKS1BP1, GTF3C3, TUBGCP3, PRPF40A, TRMT10C, URGCP, XRN2, MSH3, XRCC1, GEMIN4, DIS3L2, BCLAF1, SBF2, DHTKD1, ATXN2, ARID4B, TOR1AIP1, RPL29, NAA16, PRPF6, KIFAP3, TMEM33, WASF2, NACAD, LIG3, POLE, CKAP4, TCEB3, MTA1, GNA13, DHX38, PHF6, ELAVL4, DDX3X, CTR9, PRPF19, CAMSAP2, PRMT3, SH3PXD2B, SCAF8, MAGED1, ILF2, TONSL, PPP1R12A, SRSF5, KIAA0020, PTBP1, CAD, ACSL3, CHD1L, STAU1, MRPL38, DVL2, GNAI3, RPL10A, RPL6, MRPS5, CDK11B, MRPS34, PES1, ATP5C1, STXBP3, HNRNPLL, CHTF18, VPS39, SART3, COPA, PRPF3, UBE2O, ABCF2, HNRNPH3, EARS2, DHX40, ARHGEF7, EMC1, CASK, PTK2, SORT1, OGT, ATP12A, LMNB1, SLC4A7, PFKP, VDAC2, RBM25, ATL3, DHX36, TFIP11, EXOSC10, GTF3C1, SRSF1, PPP6C, TRAPPC9, RAD21, DNAJC13, ACOT1, ZC3H4, SRRM1, NDUFS3, DYRK1A, INTS1, SF3B2, EHHADH, MYO9B, ASCC2, WDR11, RPN1, EHD4, WDR91, SMARCAL1, NBAS, PI4KA, PAF1, EIF2B4, NUP107, EMC2, SYNE1, KLHL13, TBL1XR1, DNAJC10, SEC16A, METTL13, C7orf50, CDC42BPB, CLCN5, PGM3, DOCK7, ALYREF, POLR3A, TOP3A, WDR48, WDR81, DOCK1, CSNK2A2, CYC1, TLE3, THOC2, EIF2S3, MYO5A, SNX9, TARDBP, NAP1L4, CRKL, YTHDF2, PYGB, PABPC1, LTV1, PSMD4, KTN1, UBTF, WDR6, FUBP3, UBXN7, PHB, PDXP, CNOT3, TBL2, LLGL1, PLOD1, AHSA1, AAAS, ERGIC1, LARP4B, CYFIP1, DNM1, TARS2, ACSL1, ATXN1L, WDR59, SUCLA2, MLH1, CSNK2B, SYNCRIP, WDR36, FAM91A1, MTDH, UBE3C, CAPN1, BRIX1, DNAJB11, EDEM3, PLOD3, CLASP1, DPYSL3, MED16, NONO, EPM2AIP1, NT5DC2, ADRBK2, RPTOR, TELO2, MRPL37, PRKACB, ELMO1, TRAPPC8, ANAPC1, NIPSNAP1, EWSR1, PIK3R4, POLD1, IQGAP1, PRRC2A, COG1, ANKRD44, TFRC, DIEXF, FHOD1, SERPINH1, SPATA5, MED1, ABCF3, ZSWIM8, LMNA, HAT1, PABPC4, SMC4, HADH, RNGTT, TUBGCP2, ZNF598, SKIV2L2, GNB2L1, LARP1, DIP2B, BCR, IDH3B, LSM14A, FBL, NDUFS1, APPL2, USP39, SMC2, HCFC1, LANCL1, POLR2B, UPF2, CCBL2, MRPL15, MAGED2, AGK, GNPAT, AIMP1, GTF3C4, KDM1A, SCAMP3, RDH11, SRGAP2, CRNKL1, RFC5, PFKL, SPTBN1, PHOX2A, VDAC3, HNRNPA1, WDR26, DNM2, HAUS5, LCMT2, MCM7, CLINT1, UGDH, ACO1, TRIM46, PHKB, USP10, PCF11, YTHDF3, AARS2, FIGNL1, SFPQ, ATP5A1, NUP133, CPSF3, ANKRD28, PNN, C9orf64, ABCF1, ATL1, NAP1L1, HSPA9, MCCC2, FKBP5, CNOT1, TAF6, NEMF, UHRF1, SDHA, PELP1, HADHB, OAT, NEK9, AP3M1, PRKCA, LPCAT1, MRPL39, AFG3L2, WASF1, HNRNPL, RALGAPB, HK1, GBA, PLD3, CPSF7, HADHA, PDE12, DCX, LIMA1, HNRNPA2B1, POLR2A, MYH9, ZNF207, DDX55, ELP3, EIF2B5, MICAL1, TTI1, NES, HSDL1, GPSM1, PPM1F, C4orf27, SRRM2, OSBPL9, STAT3, IRF2BPL, KLC2, P3H1, STAT5B, UQCRC1, PCK2, CCAR2, TBC1D5, SACM1L, QARS, XPO4, CHD4, KIF2A, TACC3, NCL, BTAF1, RARS2, NCKAP1, EIF3D, RPS3, YME1L1, EIF4A3, HAUS6, HNRNPDL, MON2, G3BP2, WDHD1, CSNK1A1, SDAD1, RPS25, LSM14B, AP1M1, CCDC47, HNRNPK, DNMT1, NUP85, CUL5, TANC1, STAT1, COG5, STOML2, CDC45, OSBPL11, CIC, ABCD2, ARFGEF1, TROVE2, GBF1, SRPRB, UBE3A, GTPBP1, SCCPDH, RPS4X, PRPF4, ACTL6A, CCAR1, KIAA1033, TRAPPC12, HNRNPA3, FASTKD5, LYN, VPS18, PGRMC2, NUP214, AIFM1, TSG101, PPP6R3, OCRL, GANAB, IARS, SARS2, ATP2A2, EXOC1, NCAPH, TTC27, GNE, SRC, MIOS, ZCCHC8, GOLGA2, CARM1, ABCC1, PRMT5, LEO1, LMNB2, USP8, DARS, GYS1, APEH, ZYG11B, AKAP1, ELAVL1, MCM5, LRWD1, PSMC1, MOGS, TRIM28, EXOC6, LUC7L3, ANKFY1, NSUN2, HDAC2, G3BP1, QRICH1, INTS3, UBR1, XAB2, DYNC1LI1, TUFM, GAA, EXOC8, DHX8, LIMCH1, CLTC, SRPR, RNH1, ABI2, AQR, PREP, PPM1E, COG2, SEPT9, IDH2, MFN2, EXOC4, VPS33B, INTS4, GNB1, MSH6, HNRNPC, ERLIN1, EPRS, LRRC49, RPAP1, MCM3, PSMC4, PSMD3, GNL1, TRIP13, CUX1, PFAS, MAP1S, LRCH1, MRPL19, ABCD1, EIF3F, PDS5B, SMC3, KIF4A, FANCD2, IRF2BP1, SMC1A, RNF20, CLPX, NOC2L, DLAT, CTBP1, APPL1, NAA35, VPS45, PUM2, RELA, NUP210, RANBP9, DNAJC9, WRN, PRKAA1, AIMP2, VPS8, MAD1L1, MRE11A, ATP13A1, ATG7, CEP131, TRIM33, SLC25A10, HERC4, LRRFIP1, POLR1C, IPO9, GEMIN5, METAP2, SMG8, WASL, PPP1CB, SCFD1, RANBP3, RB1, CLTA, RNF40, SNRNP70, NCSTN, MGEA5, NARS, EIF4E, INPP4A, TFB2M, SEL1L, ARGLU1, PPP4R1, ANKRD17, TTK, RAD50, KIF2C, GOLGA3, TRAPPC11, GIGYF2, MSI2, CYFIP2, CDK5, HBS1L, IFT81, UFL1, PFKM, SMARCAD1, WDR35, PRIM2, NAMPT, PSMD2, MSH2, SOGA3, HEATR6, SFXN1, ARCN1, OGDH, FDPS, PSMC5, INSR, IRF2BP2, DDOST, ATXN2L, CSNK2A1, EIF2S2, MAP4, LTN1, COPB1, BRAT1, SMC6, SNRPN, RIC8A, SKIV2L, EIF4A1, KIF15, CLPTM1L, KPNA1, VPS16, VPS26B, RNPEP, RBM39, PMS1, FAM129B, RFC3, NUP155, RBM26, KIF21A, GAPVD1, C2CD5, WAPAL, RPS13, ARHGEF1, ACTR1A, KLC4, ISLR2, DCK, LRRC8A, STT3A, BOP1, RPN2, AFTPH, ORC3, FOXK1, CD2BP2, PDHA1, PPP6R1, PANK4, KIAA0196, WDR77, CHUK, DDX1, COLGALT1, VAPA, PPME1, CAMSAP1, RABL6, RTCB, SRRT, PIK3C3, NUMA1, STXBP1, OTUB1, UBAP2L, EXOC5, LRRC59, EXOC3, RQCD1, FLII, COPG2, USP5, XPOT, TIMM44, ATP1A1, SBF1, ARPC1B, PLK1, OSBPL8, BAG6, PPP6R2, FAM98B, VPS52, FADS2, EIF4G2, EIF4G3, HSPA8, POLR1B, PSMC6, SFSWAP, VPS33A, MCM10, AVL9, RINT1, PPIB, FBXL18, MFAP1, KIF13B, ATP2C1, ERCC2, CTTNBP2NL, WDR82, VARS, KPNA6, MIA3, HEATR1, SEC23B, AASDHPPT, POLR3B, ALDH18A1, PIKFYVE, MPP6, MRI1, CAPN7, RAB3GAP2, NCAPD2, UGGT1, IKBKAP, KDM3B, CLNS1A, FEN1, ECH1, AP2B1, HNRNPH1, RARS, AGPS, FANCI, PYCR2, EHD1, BUB3, KIF5B, SYMPK, PC, ACAA2, NDC80, PRRC2C, MTHFD1L, FASN, RANBP6, VPS11, NUP93, STRN, SCYL1, DDX19A, GTF2I, SEC23A, CTNNB1, STAM, VPRBP, VCL, PDHB, SEC24D, ERCC4, GRN, ACADM, HSPA6, ERCC6L, RPL5, ARHGAP17, DDX6, MAPK8IP3, TJP1, RIOK1, ERP29, PARG, NUP205, PALLD, COG4, TPP2, EPB41, VAC14, FUS, ZW10, KIF11, GET4, MCM6, EIF2S1, CSDE1, DHX16, GFM1, RABGAP1, TTC28, XPO1, EXOC2, DCTN1, ACBD3, RFC4, PARP1, COPG1, GPRIN1, EIF3C, CUL1, C14orf166, RTL1, STRIP1, MRPS2, PPP2R5D, EIF4G1, EXOSC4, MCM4, SEC63, WDR1, CUL4B, CRMP1, NSF, RNMT, BLVRA, UBE4A, PCBP1, MLLT4, RNF214, ARVCF, CKAP5, NUP188, SMCR8, CTNNA1, SYT1, PCM1, KNTC1, GFPT1, THYN1, SARM1, LPIN1, TIA1, NUP54, PKN1, SUMO4, DICER1, KIF3A, IPO8, CLIC4, PSMD14, GLG1, ABCE1, SMEK1, NCAPG, PPP5C, RTF1, IARS2, PDS5A, PHGDH, RPS6KA3, LONP1, ROCK1, CDK6, LARS, KPNA3, HNRNPAB, MCM2, PPP2R2A, HSP90AB2P, VCPIP1, PCBP2, RPA1, SEC24A, HECTD3, RCC2, DIS3, SMS, KHSRP, CLGN, GNAS, FOCAD, SEC23IP, ACOT7, HK2, CCDC6, MFN1, WDR7, CNN3, KIAA1524, RAB3GAP1, OXCT1, SBNO1, PRPSAP2, ACTR3, CTPS2, TMEM43, FAM21A, LRRC47, VAPB, SCYL2, STRN4, NAE1, SREK1, TFG, SF3A1, CDK2, GPKOW, GPHN, PDCD4, U2AF2, UNC45A, VPS35, NAA15, ASNS, TOP2B, ACO2, AGAP3, ROCK2, NUDT21, NPEPPS, ADD1, AP1G1, CPSF6, DNAJC2, RPS5, CTPS1, IDH1, SEC24C, KIF3B, ACTR2, CPD, EEF1D, SAMHD1, ETFB, DNM1L, LRPPRC, MCMBP, RBM12, OPA1, FARSB, UPF1, PCMT1, USO1, COG3, CLPTM1, TLK2, PRUNE, ASPSCR1, MARS, PYCR1, TCERG1, MED23, PITPNB, ARPC2, UBE4B, DBR1, ETFA, BICD1, KLC1, WDR70, PXDN, DPYSL4, USP7, CLUH, TBRG4, OGFR, SV2A, PDCD6IP, PDLIM5, PSMC2, TRAP1, DRG1, SMEK2, TCP1, TNPO2, CALD1, ARIH2, POR, FKBP3, DCTN2, NPM1, USP48, IPO13, NUP88, NNT, TAOK1, PPWD1, PSPC1, PABPN1, POLA1, MTR, BCCIP, RUVBL2, C16orf62, SORD, PPP2CA, STRN3, RUVBL1, PPP1CA, CACTIN, RPAP3, VPS51, TUBB3, PRKDC, HSPA5, CCDC132, MRPS27, RBBP4, CAPZA1, SLC4A1AP, THUMPD3, FAF1, CDK4, GSTO1, NCBP1, CAPZB, SNRPA, TXLNG, NELFE, MUT, DYNC1LI2, CTTN, DYNC1I2, TIMELESS, CBS, TTLL12, ESYT1, LAMB1, KARS, PPIL4, LRRC40, TXLNA, RAD23B, TBCE, ACAD9, THADA, GCN1L1, SLK, PNKP, ACLY, ATP6V0A1, VTA1, TXNDC5, OXSR1, ACACA, TNPO3, CCDC93, TIPRL, RAN, HOOK3, PSME4, YWHAQ, PPM1G, PSMC3, SCARB2, EXOC7, DFNA5, TRMT6, CPNE3, SLC3A2, G6PD, EIF2B1, SF3B1, EXOC6B, HGS, DYNC1H1, DNAJC7, CANX, TSR1, TTC37, DARS2, ZPR1, SERBP1, HSP90AB1, TBCB, UCHL5, IMPDH2, PUF60, RANGAP1, PDXDC1, YWHAH, LARS2, ZC3H15, GMPS, YWHAG, SUPV3L1, SPAG9, IMPDH1, HSD17B10, GTF2F1, EXOSC9, CUL3, ARHGAP35, TUBB4B, EIF5B, KIF5C, PDIA6, LDHA, ATL2, SNX1, SF3B3, SRM, MAP2, DIAPH1, DBH, NHLRC2, ELP2, GRPEL1, TWF1, WBP11, ERP44, SERPINB6, VCP, HSPH1, CMTR1, KIF1A, USP47, EML4, PRMT1, ATP6V1B2, GPS1, CAND1, CLPB, PCNA, RPLP0, CORO7, TUBB, ANXA2, API5, SUPT16H, RUFY1, KIAA1279, PDIA3, ACTA1, SF3A3, DCTN4, CUL2, WARS, PGM2, NELFB, XPO5, UGP2, HSP90B1, GSR, SHMT2, IPO11, EIF3E, RDX, DNAJB1, KIAA1598, AARS, EFTUD1, HEATR5B, ENAH, TNPO1, LIG1, NRD1, DLD, STRA6, PAFAH1B1, NT5C2, SSRP1, NTRK3, HDGFRP2, EIF3G, CSE1L, ACAT1, TBCD, NAA10, MTHFD1, RALA, EIF3A, PRPS1, ISOC1, IPO7, HNRNPD, GAPDH, U2AF1, SUPT5H, PSMD8, RPS6KA1, NUF2, GDAP1, VPS26A, TUBB2B, CDH2, TMOD1, CBR1, HDLBP, CS, HSPD1, LMAN1, EIF3B, DDB1, PSMD1, DPYSL2, STRAP, RTN4, FLNA, AHCY, HSD17B4, GOLIM4, SPTAN1, IPO4, PKM, EIF3I, SF1, BZW2, XPO7, ACADVL, STAG2, DPP9, RECQL, GDI1, GARS, MMS19, EIF2A, IPO5, TCOF1, RAB5C, SAP30BP, VDAC1, TUBA1A, SEPT2, DBNL, PLAA, TOMM70A, NOMO1, ISYNA1, CTNNA2, EEF1B2, PAK4, NELFCD, GSPT1, KPNB1, MAP1A, COPS4, YWHAZ, KPNA2, EIF4B, PLS3, COPS3, HSPBP1, AP1B1, NASP, DDX39A, LUC7L2, APMAP, SEC31A, SRSF2, TXNRD1, ATP1A3, RRM2, COG7, FSD1, PRDX4, DCPS, NCAM1, NUDCD1, NAA25, RPL9, NPLOC4, YWHAB, ATP1B1, LSS, DNAAF5, METTL16, COPS6, XPNPEP1, ELAC2, PUS7, CCT3, SFN, AGL, PAPOLA, SRSF11, ALDH2, PSME2, CKMT1B, LDHB, PSMA7, RAB11A, PPP2R1A, GNAO1, LUC7L, COPS5, IMPA1, RRM1, PPID, DPP3, KIAA0368, SLC1A5, YARS, NUP50, TPM4, ITGB1, SARS, SEZ6L2, GTF2F2, GART, ALDOC, PSMD11, EIF6, DFFA, RAP1GDS1, NELFA, CARS, CCT4, P4HB, FSCN1, PSMD13, PSMA5, CCT5, PAPSS1, OSBP, SAE1, ATP6V1A, LMAN2, YWHAE, SRP54, IDE, SNX2, RPSA, BZW1, SND1, UBQLN1, MAPK1, CALR, MARCKSL1, SUGT1, TBC1D4, GLRX3, LETM1, HMGB1, EIF3H, SLC9A3R1, DDX42, LAP3, PRKCSH, EEF2, PSMD6, BCAP31, ANXA11, ACTN1, CCT6A, PSMA4, ANXA5, CCT7, EIF3L, FUBP1, SSB, PGM1, MAPRE1, UBA2, AMPD2, PPAT, CLIC1, CCT2, ECHS1, LTA4H, USP14, CCT8, ANK2, PDIA4, TPR, NRCAM, MAT2A, HTATSF1, THOP1, RANBP1, RSRC2, NMT1, AK2, EEF1G, TPM3, PSMA3, EIF4H, GLUD1, CAP1, TKT, ATP5B, TXNL1, STIP1, HMGB2, GGH, HSPB1, CALU, RPL17, PSMA1, RSRC1, ST13, PRDX6, EIF3J, PNPT1, APEX1, TARS, MARCKS, PSMA6, EEF1A1, COPB2, NUDT5, HSPA1A, ERO1L, ME2, RPH3A, ESD, EIF5, ADSL, RUFY3, DPYSL5, ANXA6, NUDC, NANS, GOT2, GLDC, PSAT1, SET, PAK2, UBA6, UCHL1, L1CAM, PGLS, MAP1B, CCDC124, EIF3M, VAT1, PAFAH1B3, ALDOA, IRGQ, UBQLN2, NACA, OLA1, ACTN4, ARHGDIA, PSMD7, CACYBP, PSMA2, CPNE1, MDH2, PGAM1, DDX46, ACAT2, ALCAM, HARS, CKB, FKBP4, ASNA1, GPI, INA, HYOU1, CHGA, MDH1, EZR, ANP32A, UBA1, ARG1, ANP32B, PAICS, ATIC, TPI1, PPA1, TALDO1, PGK1, DDX39B, TLN1, AKR1B1, ENO1, NGFR, TPTE |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| Tgene | NTRK1 | chr12:58008800 | chr1:156841415 | ENST00000368196 | + | 5 | 16 | 469_490 | 239 | 791 | SQSTM1 |
| Tgene | NTRK1 | chr12:58008800 | chr1:156841415 | ENST00000392302 | + | 6 | 17 | 469_490 | 209 | 761 | SQSTM1 |
| Tgene | NTRK1 | chr12:58008800 | chr1:156841415 | ENST00000524377 | + | 5 | 17 | 469_490 | 239 | 797 | SQSTM1 |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for ARHGEF25_NTRK1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Tgene | NTRK1 | P04629 | DB00321 | Amitriptyline | High affinity nerve growth factor receptor | small molecule | approved |
| Tgene | NTRK1 | P04629 | DB00619 | Imatinib | High affinity nerve growth factor receptor | small molecule | approved |
| Tgene | NTRK1 | P04629 | DB08896 | Regorafenib | High affinity nerve growth factor receptor | small molecule | approved |
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RelatedDiseases for ARHGEF25_NTRK1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | NTRK1 | C0020074 | HSAN Type IV | 8 | ORPHANET;UNIPROT |
| Tgene | NTRK1 | C0005586 | Bipolar Disorder | 1 | CTD_human |
| Tgene | NTRK1 | C0017638 | Glioma | 1 | CTD_human |
| Tgene | NTRK1 | C0027796 | Neuralgia | 1 | CTD_human |
| Tgene | NTRK1 | C0027819 | Neuroblastoma | 1 | CTD_human |
| Tgene | NTRK1 | C0033975 | Psychotic Disorders | 1 | CTD_human |
| Tgene | NTRK1 | C0036341 | Schizophrenia | 1 | CTD_human |
| Tgene | NTRK1 | C0273115 | Lung Injury | 1 | CTD_human |
| Tgene | NTRK1 | C0752347 | Lewy Body Disease | 1 | CTD_human |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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