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Fusion gene ID: 25442 |
FusionGeneSummary for OPCML_MIR5095 |
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Fusion gene information | Fusion gene name: OPCML_MIR5095 | Fusion gene ID: 25442 | Hgene | Tgene | Gene symbol | OPCML | MIR5095 | Gene ID | 4978 |
Gene name | opioid binding protein/cell adhesion molecule like | ||
Synonyms | IGLON1|OBCAM|OPCM | ||
Cytomap | 11q25 | ||
Type of gene | protein-coding | ||
Description | opioid-binding protein/cell adhesion moleculeIgLON family member 1opioid binding protein/cell adhesion molecule-like preprotein | ||
Modification date | 20180522 | ||
UniProtAcc | Q14982 | ||
Ensembl transtripts involved in fusion gene | ENST00000524381, ENST00000529038, ENST00000331898, ENST00000374778, ENST00000541867, | ENST00000578844, | |
Fusion gene scores | * DoF score | 2 X 2 X 1=4 | 3 X 3 X 1=9 |
# samples | 2 | 3 | |
** MAII score | log2(2/4*10)=2.32192809488736 | log2(3/9*10)=1.73696559416621 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
Context | PubMed: OPCML [Title/Abstract] AND MIR5095 [Title/Abstract] AND fusion [Title/Abstract] | ||
Functional or gene categories assigned by FusionGDB annotation |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
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Partner | Gene | GO ID | GO term | PubMed ID |
![]() (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChiTaRS3.1 | BF856072 | OPCML | chr11 | 132542973 | + | MIR5095 | chr20 | 55948608 | + |
* LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
intron-intron | ENST00000524381 | ENST00000578844 | OPCML | chr11 | 132542973 | + | MIR5095 | chr20 | 55948608 | + |
intron-intron | ENST00000529038 | ENST00000578844 | OPCML | chr11 | 132542973 | + | MIR5095 | chr20 | 55948608 | + |
intron-intron | ENST00000331898 | ENST00000578844 | OPCML | chr11 | 132542973 | + | MIR5095 | chr20 | 55948608 | + |
intron-intron | ENST00000374778 | ENST00000578844 | OPCML | chr11 | 132542973 | + | MIR5095 | chr20 | 55948608 | + |
intron-intron | ENST00000541867 | ENST00000578844 | OPCML | chr11 | 132542973 | + | MIR5095 | chr20 | 55948608 | + |
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FusionProtFeatures for OPCML_MIR5095 |
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Hgene | Tgene |
OPCML | MIR5095 |
Binds opioids in the presence of acidic lipids; probablyinvolved in cell contact. | Lectin that binds to various sugars: galactose > mannose= fucose > N-acetylglucosamine > N-acetylgalactosamine(PubMed:10224141). Acts as a chemoattractant, probably involved inthe regulation of cell migration (PubMed:28301481).{ECO:0000269|PubMed:10224141, ECO:0000269|PubMed:28301481}. |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for OPCML_MIR5095 |
![]() (nt: nucleotides, aa: amino acids) |
* Fusion amino acid sequences. |
* Fusion transcript sequences (only coding sequence (CDS) region). |
* Fusion transcript sequences (Full-length transcript). |
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FusionGenePPI for OPCML_MIR5095 |
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Hgene | Hgene's interactors | Tgene | Tgene's interactors |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for OPCML_MIR5095 |
![]() (DrugBank Version 5.1.0 2018-04-02) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for OPCML_MIR5095 |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Hgene | OPCML | C0036341 | Schizophrenia | 1 | PSYGENET |
Hgene | OPCML | C1140680 | Malignant neoplasm of ovary | 1 | UNIPROT |