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Fusion gene ID: 25397 |
FusionGeneSummary for OIP5-AS1_SLC36A2 |
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Fusion gene information | Fusion gene name: OIP5-AS1_SLC36A2 | Fusion gene ID: 25397 | Hgene | Tgene | Gene symbol | OIP5-AS1 | SLC36A2 | Gene ID | 729082 | 153201 |
Gene name | OIP5 antisense RNA 1 | solute carrier family 36 member 2 | |
Synonyms | cyrano|linc-OIP5 | PAT2|TRAMD1 | |
Cytomap | 15q15.1 | 5q33.1 | |
Type of gene | ncRNA | protein-coding | |
Description | OIP5 antisense RNA 1 (non-protein coding) | proton-coupled amino acid transporter 2solute carrier family 36 (proton/amino acid symporter), member 2tramdorin-1 | |
Modification date | 20180428 | 20180523 | |
UniProtAcc | Q495M3 | ||
Ensembl transtripts involved in fusion gene | ENST00000500949, | ENST00000335244, ENST00000450886, ENST00000521967, | |
Fusion gene scores | * DoF score | 3 X 3 X 1=9 | 1 X 1 X 1=1 |
# samples | 3 | 1 | |
** MAII score | log2(3/9*10)=1.73696559416621 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(1/1*10)=3.32192809488736 | |
Context | PubMed: OIP5-AS1 [Title/Abstract] AND SLC36A2 [Title/Abstract] AND fusion [Title/Abstract] | ||
Functional or gene categories assigned by FusionGDB annotation |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
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Partner | Gene | GO ID | GO term | PubMed ID |
![]() (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChiTaRS3.1 | AI469343 | OIP5-AS1 | chr15 | 41591060 | - | SLC36A2 | chr5 | 150713380 | + |
* LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
![]() * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
3UTR-intron | ENST00000500949 | ENST00000335244 | OIP5-AS1 | chr15 | 41591060 | - | SLC36A2 | chr5 | 150713380 | + |
3UTR-intron | ENST00000500949 | ENST00000450886 | OIP5-AS1 | chr15 | 41591060 | - | SLC36A2 | chr5 | 150713380 | + |
3UTR-intron | ENST00000500949 | ENST00000521967 | OIP5-AS1 | chr15 | 41591060 | - | SLC36A2 | chr5 | 150713380 | + |
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FusionProtFeatures for OIP5-AS1_SLC36A2 |
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Hgene | Tgene |
OIP5-AS1 | SLC36A2 |
Lectin that binds to various sugars: galactose > mannose= fucose > N-acetylglucosamine > N-acetylgalactosamine(PubMed:10224141). Acts as a chemoattractant, probably involved inthe regulation of cell migration (PubMed:28301481).{ECO:0000269|PubMed:10224141, ECO:0000269|PubMed:28301481}. | Involved in a pH-dependent electrogenic neuronaltransport and sequestration of small amino acids. Transportsglycine and proline. Inhibited by sarcosine (By similarity).{ECO:0000250, ECO:0000269|PubMed:19033659}. |
![]() * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for OIP5-AS1_SLC36A2 |
![]() (nt: nucleotides, aa: amino acids) |
* Fusion amino acid sequences. |
* Fusion transcript sequences (only coding sequence (CDS) region). |
* Fusion transcript sequences (Full-length transcript). |
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FusionGenePPI for OIP5-AS1_SLC36A2 |
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Hgene | Hgene's interactors | Tgene | Tgene's interactors |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for OIP5-AS1_SLC36A2 |
![]() (DrugBank Version 5.1.0 2018-04-02) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for OIP5-AS1_SLC36A2 |
![]() (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Tgene | SLC36A2 | C0543541 | HYPERGLYCINURIA (disorder) | 1 | CTD_human;UNIPROT |