FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

FusionGeneSummary

leaf

FusionProtFeature

leaf

FusionGeneSequence

leaf

FusionGenePPI

leaf

RelatedDrugs

leaf

RelatedDiseases

Fusion gene ID: 25343

FusionGeneSummary for OBSCN_CASZ1

check button Fusion gene summary
Fusion gene informationFusion gene name: OBSCN_CASZ1
Fusion gene ID: 25343
HgeneTgene
Gene symbol

OBSCN

CASZ1

Gene ID

84033

54897

Gene nameobscurin, cytoskeletal calmodulin and titin-interacting RhoGEFcastor zinc finger 1
SynonymsARHGEF30|UNC89CAS11|CST|SRG|ZNF693|dJ734G22.1
Cytomap

1q42.13

1p36.22

Type of geneprotein-codingprotein-coding
Descriptionobscurinobscurin, myosin light chain kinaseobscurin-MLCKzinc finger protein castor homolog 1castor homolog 1, zinc fingercastor-related proteinsurvival-relatedzinc finger protein 693
Modification date2018051920180523
UniProtAcc

Q5VST9

Q86V15

Ensembl transtripts involved in fusion geneENST00000284548, ENST00000570156, 
ENST00000366709, ENST00000422127, 
ENST00000366707, ENST00000359599, 
ENST00000602685, 		ENST00000377022, 
ENST00000344008, ENST00000478728, 
Fusion gene scores* DoF score5 X 6 X 3=903 X 3 X 2=18
# samples 53
** MAII scorelog2(5/90*10)=-0.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(3/18*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: OBSCN [Title/Abstract] AND CASZ1 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneCASZ1

GO:0045893

positive regulation of transcription, DNA-templated

27693370


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVHNSCTCGA-BB-4223-01AOBSCNchr1

228412435

+CASZ1chr1

10725628

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000284548ENST00000377022OBSCNchr1

228412435

+CASZ1chr1

10725628

-
In-frameENST00000284548ENST00000344008OBSCNchr1

228412435

+CASZ1chr1

10725628

-
5CDS-5UTRENST00000284548ENST00000478728OBSCNchr1

228412435

+CASZ1chr1

10725628

-
In-frameENST00000570156ENST00000377022OBSCNchr1

228412435

+CASZ1chr1

10725628

-
In-frameENST00000570156ENST00000344008OBSCNchr1

228412435

+CASZ1chr1

10725628

-
5CDS-5UTRENST00000570156ENST00000478728OBSCNchr1

228412435

+CASZ1chr1

10725628

-
5UTR-3CDSENST00000366709ENST00000377022OBSCNchr1

228412435

+CASZ1chr1

10725628

-
5UTR-3CDSENST00000366709ENST00000344008OBSCNchr1

228412435

+CASZ1chr1

10725628

-
5UTR-5UTRENST00000366709ENST00000478728OBSCNchr1

228412435

+CASZ1chr1

10725628

-
In-frameENST00000422127ENST00000377022OBSCNchr1

228412435

+CASZ1chr1

10725628

-
In-frameENST00000422127ENST00000344008OBSCNchr1

228412435

+CASZ1chr1

10725628

-
5CDS-5UTRENST00000422127ENST00000478728OBSCNchr1

228412435

+CASZ1chr1

10725628

-
5UTR-3CDSENST00000366707ENST00000377022OBSCNchr1

228412435

+CASZ1chr1

10725628

-
5UTR-3CDSENST00000366707ENST00000344008OBSCNchr1

228412435

+CASZ1chr1

10725628

-
5UTR-5UTRENST00000366707ENST00000478728OBSCNchr1

228412435

+CASZ1chr1

10725628

-
intron-3CDSENST00000359599ENST00000377022OBSCNchr1

228412435

+CASZ1chr1

10725628

-
intron-3CDSENST00000359599ENST00000344008OBSCNchr1

228412435

+CASZ1chr1

10725628

-
intron-5UTRENST00000359599ENST00000478728OBSCNchr1

228412435

+CASZ1chr1

10725628

-
intron-3CDSENST00000602685ENST00000377022OBSCNchr1

228412435

+CASZ1chr1

10725628

-
intron-3CDSENST00000602685ENST00000344008OBSCNchr1

228412435

+CASZ1chr1

10725628

-
intron-5UTRENST00000602685ENST00000478728OBSCNchr1

228412435

+CASZ1chr1

10725628

-

Top

FusionProtFeatures for OBSCN_CASZ1


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
OBSCN

Q5VST9

CASZ1

Q86V15


check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+981192_1989766621Compositional biasNote=Poly-Ala
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+981710_7139766621Compositional biasNote=Poly-Ala
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+981931_9349766621Compositional biasNote=Poly-Ser
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+9105192_1989767969Compositional biasNote=Poly-Ala
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+9105710_7139767969Compositional biasNote=Poly-Ala
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+9105931_9349767969Compositional biasNote=Poly-Ser
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+98110_1009766621DomainNote=Ig-like 1
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+981110_2029766621DomainNote=Ig-like 2
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+981236_3229766621DomainNote=Ig-like 3
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+981331_4149766621DomainNote=Ig-like 4
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+981420_5089766621DomainNote=Ig-like 5
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+981515_6129766621DomainFibronectin type-III 1
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+981619_6989766621DomainNote=Ig-like 6
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+981701_7909766621DomainNote=Ig-like 7
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+981798_8849766621DomainNote=Ig-like 8
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+981886_9779766621DomainNote=Ig-like 9
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+910510_1009767969DomainNote=Ig-like 1
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+9105110_2029767969DomainNote=Ig-like 2
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+9105236_3229767969DomainNote=Ig-like 3
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+9105331_4149767969DomainNote=Ig-like 4
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+9105420_5089767969DomainNote=Ig-like 5
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+9105515_6129767969DomainFibronectin type-III 1
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+9105619_6989767969DomainNote=Ig-like 6
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+9105701_7909767969DomainNote=Ig-like 7
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+9105798_8849767969DomainNote=Ig-like 8
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+9105886_9779767969DomainNote=Ig-like 9
TgeneCASZ1chr1:228412435chr1:10725628ENST00000344008-3161080_114351167Compositional biasNote=Pro-rich
TgeneCASZ1chr1:228412435chr1:10725628ENST00000344008-3161635_167051167Compositional biasNote=Ala-rich
TgeneCASZ1chr1:228412435chr1:10725628ENST00000344008-3161672_172951167Compositional biasNote=Glu-rich
TgeneCASZ1chr1:228412435chr1:10725628ENST00000344008-3161691_171851167Compositional biasNote=Asp-rich
TgeneCASZ1chr1:228412435chr1:10725628ENST00000344008-316384_41751167Compositional biasNote=Pro-rich
TgeneCASZ1chr1:228412435chr1:10725628ENST00000377022-3211080_114351760Compositional biasNote=Pro-rich
TgeneCASZ1chr1:228412435chr1:10725628ENST00000377022-3211635_167051760Compositional biasNote=Ala-rich
TgeneCASZ1chr1:228412435chr1:10725628ENST00000377022-3211672_172951760Compositional biasNote=Glu-rich
TgeneCASZ1chr1:228412435chr1:10725628ENST00000377022-3211691_171851760Compositional biasNote=Asp-rich
TgeneCASZ1chr1:228412435chr1:10725628ENST00000377022-321384_41751760Compositional biasNote=Pro-rich
TgeneCASZ1chr1:228412435chr1:10725628ENST00000344008-3161031_105551167Zinc fingerC2H2-type 4
TgeneCASZ1chr1:228412435chr1:10725628ENST00000344008-3161300_132451167Zinc fingerC2H2-type 5
TgeneCASZ1chr1:228412435chr1:10725628ENST00000344008-3161457_148151167Zinc fingerC2H2-type 6
TgeneCASZ1chr1:228412435chr1:10725628ENST00000344008-3161515_153751167Zinc fingerC2H2-type 7
TgeneCASZ1chr1:228412435chr1:10725628ENST00000344008-3161571_159551167Zinc fingerC2H2-type 8
TgeneCASZ1chr1:228412435chr1:10725628ENST00000344008-316551_57551167Zinc fingerC2H2-type 1
TgeneCASZ1chr1:228412435chr1:10725628ENST00000344008-316610_63451167Zinc fingerC2H2-type 2
TgeneCASZ1chr1:228412435chr1:10725628ENST00000344008-316668_69251167Zinc fingerC2H2-type 3
TgeneCASZ1chr1:228412435chr1:10725628ENST00000377022-3211031_105551760Zinc fingerC2H2-type 4
TgeneCASZ1chr1:228412435chr1:10725628ENST00000377022-3211300_132451760Zinc fingerC2H2-type 5
TgeneCASZ1chr1:228412435chr1:10725628ENST00000377022-3211457_148151760Zinc fingerC2H2-type 6
TgeneCASZ1chr1:228412435chr1:10725628ENST00000377022-3211515_153751760Zinc fingerC2H2-type 7
TgeneCASZ1chr1:228412435chr1:10725628ENST00000377022-3211571_159551760Zinc fingerC2H2-type 8
TgeneCASZ1chr1:228412435chr1:10725628ENST00000377022-321551_57551760Zinc fingerC2H2-type 1
TgeneCASZ1chr1:228412435chr1:10725628ENST00000377022-321610_63451760Zinc fingerC2H2-type 2
TgeneCASZ1chr1:228412435chr1:10725628ENST00000377022-321668_69251760Zinc fingerC2H2-type 3

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9811115_11189766621Compositional biasNote=Poly-Ser
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9811207_12109766621Compositional biasNote=Poly-Ser
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9811299_13029766621Compositional biasNote=Poly-Ser
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9811391_13949766621Compositional biasNote=Poly-Ser
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9811575_15789766621Compositional biasNote=Poly-Ser
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9811667_16709766621Compositional biasNote=Poly-Ser
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9814398_44019766621Compositional biasNote=Poly-Leu
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9814846_48499766621Compositional biasNote=Poly-Gln
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9816789_67969766621Compositional biasNote=Poly-Ser
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9816969_71179766621Compositional biasNote=Pro-rich
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91051115_11189767969Compositional biasNote=Poly-Ser
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91051207_12109767969Compositional biasNote=Poly-Ser
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91051299_13029767969Compositional biasNote=Poly-Ser
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91051391_13949767969Compositional biasNote=Poly-Ser
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91051575_15789767969Compositional biasNote=Poly-Ser
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91051667_16709767969Compositional biasNote=Poly-Ser
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91054398_44019767969Compositional biasNote=Poly-Leu
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91054846_48499767969Compositional biasNote=Poly-Gln
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91056789_67969767969Compositional biasNote=Poly-Ser
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91056969_71179767969Compositional biasNote=Pro-rich
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9811070_11619766621DomainNote=Ig-like 11
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9811162_12529766621DomainNote=Ig-like 12
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9811254_13459766621DomainNote=Ig-like 13
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9811346_14329766621DomainNote=Ig-like 14
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9811438_15249766621DomainNote=Ig-like 15
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9811530_16219766621DomainNote=Ig-like 16
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9811622_17199766621DomainNote=Ig-like 17
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9811731_18089766621DomainFibronectin type-III 2
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9811809_18949766621DomainNote=Ig-like 18
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9811896_19829766621DomainNote=Ig-like 19
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9811987_20719766621DomainNote=Ig-like 20
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9812077_21629766621DomainNote=Ig-like 21
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9812165_22499766621DomainNote=Ig-like 22
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9812289_23809766621DomainNote=Ig-like 23
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9812468_25599766621DomainNote=Ig-like 24
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9812564_26439766621DomainNote=Ig-like 25
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9812646_27309766621DomainNote=Ig-like 26
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9812736_28239766621DomainNote=Ig-like 27
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9812826_29089766621DomainNote=Ig-like 28
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9812920_29999766621DomainNote=Ig-like 29
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9813003_30929766621DomainNote=Ig-like 30
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9813095_31839766621DomainNote=Ig-like 31
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9813184_32689766621DomainNote=Ig-like 32
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9813273_33569766621DomainNote=Ig-like 33
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9813359_34449766621DomainNote=Ig-like 34
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9813449_35329766621DomainNote=Ig-like 35
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9813537_36209766621DomainNote=Ig-like 36
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9813625_37089766621DomainNote=Ig-like 37
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9813713_37969766621DomainNote=Ig-like 38
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9813801_38849766621DomainNote=Ig-like 39
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9813890_39739766621DomainNote=Ig-like 40
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9813978_40629766621DomainNote=Ig-like 41
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9814068_41609766621DomainNote=Ig-like 42
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9814171_42399766621DomainNote=Ig-like 43
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9814248_43379766621DomainNote=Ig-like 44
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9814340_44279766621DomainNote=Ig-like 45
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9814430_45189766621DomainNote=Ig-like 46
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9814525_46199766621DomainFibronectin type-III 3
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9814624_47149766621DomainNote=Ig-like 47
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9814872_49019766621DomainIQ
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9814898_49899766621DomainNote=Ig-like 48
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9815126_52159766621DomainNote=Ig-like 49
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9815260_53499766621DomainNote=Ig-like 50
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9815371_54679766621DomainNote=Ig-like 51
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9815600_56679766621DomainSH3
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9815693_58779766621DomainDH
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9815895_60049766621DomainPH
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9816014_60979766621DomainNote=Ig-like 52
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9816108_62009766621DomainNote=Ig-like 53
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9816357_64459766621DomainNote=Ig-like 54
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9816468_67219766621DomainProtein kinase 1
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9817463_75529766621DomainNote=Ig-like 55
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9817557_76499766621DomainFibronectin type-III 4
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9817672_79249766621DomainProtein kinase 2
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+981978_10669766621DomainNote=Ig-like 10
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91051070_11619767969DomainNote=Ig-like 11
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91051162_12529767969DomainNote=Ig-like 12
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91051254_13459767969DomainNote=Ig-like 13
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91051346_14329767969DomainNote=Ig-like 14
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91051438_15249767969DomainNote=Ig-like 15
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91051530_16219767969DomainNote=Ig-like 16
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91051622_17199767969DomainNote=Ig-like 17
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91051731_18089767969DomainFibronectin type-III 2
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91051809_18949767969DomainNote=Ig-like 18
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91051896_19829767969DomainNote=Ig-like 19
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91051987_20719767969DomainNote=Ig-like 20
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91052077_21629767969DomainNote=Ig-like 21
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91052165_22499767969DomainNote=Ig-like 22
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91052289_23809767969DomainNote=Ig-like 23
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91052468_25599767969DomainNote=Ig-like 24
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91052564_26439767969DomainNote=Ig-like 25
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91052646_27309767969DomainNote=Ig-like 26
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91052736_28239767969DomainNote=Ig-like 27
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91052826_29089767969DomainNote=Ig-like 28
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91052920_29999767969DomainNote=Ig-like 29
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91053003_30929767969DomainNote=Ig-like 30
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91053095_31839767969DomainNote=Ig-like 31
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91053184_32689767969DomainNote=Ig-like 32
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91053273_33569767969DomainNote=Ig-like 33
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91053359_34449767969DomainNote=Ig-like 34
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91053449_35329767969DomainNote=Ig-like 35
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91053537_36209767969DomainNote=Ig-like 36
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91053625_37089767969DomainNote=Ig-like 37
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91053713_37969767969DomainNote=Ig-like 38
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91053801_38849767969DomainNote=Ig-like 39
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91053890_39739767969DomainNote=Ig-like 40
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91053978_40629767969DomainNote=Ig-like 41
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91054068_41609767969DomainNote=Ig-like 42
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91054171_42399767969DomainNote=Ig-like 43
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91054248_43379767969DomainNote=Ig-like 44
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91054340_44279767969DomainNote=Ig-like 45
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91054430_45189767969DomainNote=Ig-like 46
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91054525_46199767969DomainFibronectin type-III 3
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91054624_47149767969DomainNote=Ig-like 47
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91054872_49019767969DomainIQ
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91054898_49899767969DomainNote=Ig-like 48
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91055126_52159767969DomainNote=Ig-like 49
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91055260_53499767969DomainNote=Ig-like 50
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91055371_54679767969DomainNote=Ig-like 51
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91055600_56679767969DomainSH3
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91055693_58779767969DomainDH
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91055895_60049767969DomainPH
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91056014_60979767969DomainNote=Ig-like 52
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91056108_62009767969DomainNote=Ig-like 53
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91056357_64459767969DomainNote=Ig-like 54
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91056468_67219767969DomainProtein kinase 1
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91057463_75529767969DomainNote=Ig-like 55
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91057557_76499767969DomainFibronectin type-III 4
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91057672_79249767969DomainProtein kinase 2
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+9105978_10669767969DomainNote=Ig-like 10
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9816474_64829766621Nucleotide bindingATP
HgeneOBSCNchr1:228412435chr1:10725628ENST00000284548+9817678_76869766621Nucleotide bindingATP
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91056474_64829767969Nucleotide bindingATP
HgeneOBSCNchr1:228412435chr1:10725628ENST00000422127+91057678_76869767969Nucleotide bindingATP


Top

FusionGeneSequence for OBSCN_CASZ1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_OBSCN_ENST00000284548_chr1_228412435_+_CASZ1_ENST00000377022_chr1_10725628_-_2731aa
MDQPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCRARNAIGE
AFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGG
TYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETV
WKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLCEVPQPS
TEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETPEGSRTVAELAVQGNLLRKLPRKTAVRVGDTAMFCVELAVPVGP
VHWLRNQEEVVAGGRVAISAEGTRHTLTISQCCLEDVGQVAFMAGDCQTSTQFCVSAPRKPPLQPPVDPVVKARMESSVILSWSPPPHGE
RPVTIDGYLVEKKKLGTYTWIRCHEAEWVATPELTVADVAEEGNFQFRVSALNSFGQSPYLEFPGTVHLAPKLAVRTPLKAVQAVEGGEV
TFSVDLTVASAGEWFLDGQALKASSVYEIHCDRTRHTLTIREVPASLHGAQLKFVANGIESSIRMEVRAAPGLTANKPPAAAAREVLARL
HEEAQLLAELSDQAAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSRGGRIAYQLSVQGLARFLHKDMAGSCVDAV
AGGPAQFECETSEAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEGTYSCRVGEDSVDFRLRVSEPKVVFAKEQLARRKL
QAEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEAGGQRLSFHLDVKAEGTRCTDPPAGKP
AMAPKRKGGLKLNAICAKLSRQVVVEKRADAGSHTEGSPSQPRDQERSGPESGAARAPRSEEDKRRAVIEKWVNGEYSEEPAPTPVLGRI
AREGLELPPEGVYMVQPQGCSDEEDHAEEPSKDGGALEEKDSDGAASKEDSGPSTRQASGEASSLRDYAASTMTEFLGMFGYDDQNTRDE
LARKISFEKLHAGSTPEAATSSMLPTSEDTLSKRARFSKYEEYIRKLKAGEQLSWPAPSTKTEERVGKEVVGTLPGLRLPSSTAHLETKA
TILPLPSHSSVQMQNLVARASKYDFFIQKLKTGENLRPQNGSTYKKPSKYDLENVKYLHLFKPGEGSPDMGGAIAFKTGKVGRPSKYDVR
GIQKPGPAKVPPTPSLAPAPLASVPSAPSAPGPGPEPPASLSFNTPEYLKSTFSKTDSITTGTVSTVKNGLPTDKPAVTEDVNIYQKYIA
RFSGSQHCGHIHCAYQYREHYHCLDPECNYQRFTSKQDVIRHYNMHKKRDNSLQHGFMRFSPLDDCSVYYHGCHLNGKSTHYHCMQVGCN
KVYTSTSDVMTHENFHKKNTQLINDGFQRFRATEDCGTADCQFYGQKTTHFHCRRPGCTFTFKNKCDIEKHKSYHIKDDAYAKDGFKKFY
KYEECKYEGCVYSKATNHFHCIRAGCGFTFTSTSQMTSHKRKHERRHIRSSGALGLPPSLLGAKDTEHEESSNDDLVDFSALSSKNSSLS
ASPTSQQSSASLAAATAATEAGPSATKPPNSKISGLLPQGLPGSIPLALALSNSGLPTPTPYFPILAGRGSTSLPVGTPSLLGAVSSGSA
ASATPDTPTLVASGAGDSAPVAAASVPAPPASIMERISASKGLISPMMARLAAAALKPSATFDPGSGQQVTPARFPPAQVKPEPGESTGA
PGPHEASQDRSLDLTVKEPSNESNGHAVPANSSLLSSLMNKMSQGNPGLGSLLNIKAEAEGSPAAEPSPFLGKAVKALVQEKLAEPWKVY
LRRFGTKDFCDGQCDFLHKAHFHCVVEECGALFSTLDGAIKHANFHFRTEGGAAKGNTEAAFPASAAETKPPMAPSSPPVPPVTTATVSS
LEGPAPSPASVPSTPTLLAWKQLASTIPQMPQIPASVPHLPASPLATTSLENAKPQVKPGFLQFQENDPCLATDCKYANKFHFHCLFGNC
KYVCKTSGKAESHCLDHINPNNNLVNVRDQFAYYSLQCLCPNQHCEFRMRGHYHCLRTGCYFVTNITTKLPWHIKKHEKAERRAANGFKY
FTKREECGRLGCKYNQVNSHFHCIREGCQFSFLLKHQMTSHARKHMRRMLGKNFDRVPPSQGPPGLMDAETDECMDYTGCSPGAMSSESS
TMDRSCSSTPVGNESTAAGNTISMPTASGAKKRFWIIEDMSPFGKRRKTASSRKMLDEGMMLEGFRRFDLYEDCKDAACQFSLKVTHYHC
TRENCGYKFCGRTHMYKHAQHHDRVDNLVLDDFKRFKASLSCHFADCPFSGTSTHFHCLRCRFRCTDSTKVTAHRKHHGKQDVISAAGFC
QFSSSADCAVPDCKYKLKCSHFHCTFPGCRHTVVGMSQMDSHKRKHEKQERGEPAAEGPAPGPPISLDGSLSLGAEPGSLLFLQSAAAGL
GLALGDAGDPGPPDAAAPGPREGAAAAAAAAGESSQEDEEEELELPEEEAEDDEDEDDDEDDDDEDDDEDDDDEDLRTDSEESLPEAAAE

>In-frame_OBSCN_ENST00000284548_chr1_228412435_+_CASZ1_ENST00000344008_chr1_10725628_-_2138aa
MDQPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCRARNAIGE
AFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGG
TYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETV
WKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLCEVPQPS
TEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETPEGSRTVAELAVQGNLLRKLPRKTAVRVGDTAMFCVELAVPVGP
VHWLRNQEEVVAGGRVAISAEGTRHTLTISQCCLEDVGQVAFMAGDCQTSTQFCVSAPRKPPLQPPVDPVVKARMESSVILSWSPPPHGE
RPVTIDGYLVEKKKLGTYTWIRCHEAEWVATPELTVADVAEEGNFQFRVSALNSFGQSPYLEFPGTVHLAPKLAVRTPLKAVQAVEGGEV
TFSVDLTVASAGEWFLDGQALKASSVYEIHCDRTRHTLTIREVPASLHGAQLKFVANGIESSIRMEVRAAPGLTANKPPAAAAREVLARL
HEEAQLLAELSDQAAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSRGGRIAYQLSVQGLARFLHKDMAGSCVDAV
AGGPAQFECETSEAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEGTYSCRVGEDSVDFRLRVSEPKVVFAKEQLARRKL
QAEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEAGGQRLSFHLDVKAEGTRCTDPPAGKP
AMAPKRKGGLKLNAICAKLSRQVVVEKRADAGSHTEGSPSQPRDQERSGPESGAARAPRSEEDKRRAVIEKWVNGEYSEEPAPTPVLGRI
AREGLELPPEGVYMVQPQGCSDEEDHAEEPSKDGGALEEKDSDGAASKEDSGPSTRQASGEASSLRDYAASTMTEFLGMFGYDDQNTRDE
LARKISFEKLHAGSTPEAATSSMLPTSEDTLSKRARFSKYEEYIRKLKAGEQLSWPAPSTKTEERVGKEVVGTLPGLRLPSSTAHLETKA
TILPLPSHSSVQMQNLVARASKYDFFIQKLKTGENLRPQNGSTYKKPSKYDLENVKYLHLFKPGEGSPDMGGAIAFKTGKVGRPSKYDVR
GIQKPGPAKVPPTPSLAPAPLASVPSAPSAPGPGPEPPASLSFNTPEYLKSTFSKTDSITTGTVSTVKNGLPTDKPAVTEDVNIYQKYIA
RFSGSQHCGHIHCAYQYREHYHCLDPECNYQRFTSKQDVIRHYNMHKKRDNSLQHGFMRFSPLDDCSVYYHGCHLNGKSTHYHCMQVGCN
KVYTSTSDVMTHENFHKKNTQLINDGFQRFRATEDCGTADCQFYGQKTTHFHCRRPGCTFTFKNKCDIEKHKSYHIKDDAYAKDGFKKFY
KYEECKYEGCVYSKATNHFHCIRAGCGFTFTSTSQMTSHKRKHERRHIRSSGALGLPPSLLGAKDTEHEESSNDDLVDFSALSSKNSSLS
ASPTSQQSSASLAAATAATEAGPSATKPPNSKISGLLPQGLPGSIPLALALSNSGLPTPTPYFPILAGRGSTSLPVGTPSLLGAVSSGSA
ASATPDTPTLVASGAGDSAPVAAASVPAPPASIMERISASKGLISPMMARLAAAALKPSATFDPGSGQQVTPARFPPAQVKPEPGESTGA
PGPHEASQDRSLDLTVKEPSNESNGHAVPANSSLLSSLMNKMSQGNPGLGSLLNIKAEAEGSPAAEPSPFLGKAVKALVQEKLAEPWKVY
LRRFGTKDFCDGQCDFLHKAHFHCVVEECGALFSTLDGAIKHANFHFRTEGGAAKGNTEAAFPASAAETKPPMAPSSPPVPPVTTATVSS

>In-frame_OBSCN_ENST00000570156_chr1_228412435_+_CASZ1_ENST00000377022_chr1_10725628_-_2823aa
MDQPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCRARNAIGE
AFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGG
TYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETV
WKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLCEVPQPS
TEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETPEGSRTVAELAVQGNLLRKLPRKTAVRVGDTAMFCVELAVPVGP
VHWLRNQEEVVAGGRVAISAEGTRHTLTISQCCLEDVGQVAFMAGDCQTSTQFCVSAPRKPPLQPPVDPVVKARMESSVILSWSPPPHGE
RPVTIDGYLVEKKKLGTYTWIRCHEAEWVATPELTVADVAEEGNFQFRVSALNSFGQSPYLEFPGTVHLAPKLAVRTPLKAVQAVEGGEV
TFSVDLTVASAGEWFLDGQALKASSVYEIHCDRTRHTLTIREVPASLHGAQLKFVANGIESSIRMEVRAAPGLTANKPPAAAAREVLARL
HEEAQLLAELSDQAAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSRGGRIAYQLSVQGLARFLHKDMAGSCVDAV
AGGPAQFECETSEAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEGTYSCRVGEDSVDFRLRVSEPKAVFAKEQPACREV
QAEVGASATLSCEVAQDQMEVTWYKDGKKLSSSSKVHVEAVGCMRRLVVQQVGQADSGEYSCEARGQRVSFRLDVAEPKVVFAKEQLARR
KLQAEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEAGGQRLSFHLDVKAEGTRCTDPPAG
KPAMAPKRKGGLKLNAICAKLSRQVVVEKRADAGSHTEGSPSQPRDQERSGPESGAARAPRSEEDKRRAVIEKWVNGEYSEEPAPTPVLG
RIAREGLELPPEGVYMVQPQGCSDEEDHAEEPSKDGGALEEKDSDGAASKEDSGPSTRQASGEASSLRDYAASTMTEFLGMFGYDDQNTR
DELARKISFEKLHAGSTPEAATSSMLPTSEDTLSKRARFSKYEEYIRKLKAGEQLSWPAPSTKTEERVGKEVVGTLPGLRLPSSTAHLET
KATILPLPSHSSVQMQNLVARASKYDFFIQKLKTGENLRPQNGSTYKKPSKYDLENVKYLHLFKPGEGSPDMGGAIAFKTGKVGRPSKYD
VRGIQKPGPAKVPPTPSLAPAPLASVPSAPSAPGPGPEPPASLSFNTPEYLKSTFSKTDSITTGTVSTVKNGLPTDKPAVTEDVNIYQKY
IARFSGSQHCGHIHCAYQYREHYHCLDPECNYQRFTSKQDVIRHYNMHKKRDNSLQHGFMRFSPLDDCSVYYHGCHLNGKSTHYHCMQVG
CNKVYTSTSDVMTHENFHKKNTQLINDGFQRFRATEDCGTADCQFYGQKTTHFHCRRPGCTFTFKNKCDIEKHKSYHIKDDAYAKDGFKK
FYKYEECKYEGCVYSKATNHFHCIRAGCGFTFTSTSQMTSHKRKHERRHIRSSGALGLPPSLLGAKDTEHEESSNDDLVDFSALSSKNSS
LSASPTSQQSSASLAAATAATEAGPSATKPPNSKISGLLPQGLPGSIPLALALSNSGLPTPTPYFPILAGRGSTSLPVGTPSLLGAVSSG
SAASATPDTPTLVASGAGDSAPVAAASVPAPPASIMERISASKGLISPMMARLAAAALKPSATFDPGSGQQVTPARFPPAQVKPEPGEST
GAPGPHEASQDRSLDLTVKEPSNESNGHAVPANSSLLSSLMNKMSQGNPGLGSLLNIKAEAEGSPAAEPSPFLGKAVKALVQEKLAEPWK
VYLRRFGTKDFCDGQCDFLHKAHFHCVVEECGALFSTLDGAIKHANFHFRTEGGAAKGNTEAAFPASAAETKPPMAPSSPPVPPVTTATV
SSLEGPAPSPASVPSTPTLLAWKQLASTIPQMPQIPASVPHLPASPLATTSLENAKPQVKPGFLQFQENDPCLATDCKYANKFHFHCLFG
NCKYVCKTSGKAESHCLDHINPNNNLVNVRDQFAYYSLQCLCPNQHCEFRMRGHYHCLRTGCYFVTNITTKLPWHIKKHEKAERRAANGF
KYFTKREECGRLGCKYNQVNSHFHCIREGCQFSFLLKHQMTSHARKHMRRMLGKNFDRVPPSQGPPGLMDAETDECMDYTGCSPGAMSSE
SSTMDRSCSSTPVGNESTAAGNTISMPTASGAKKRFWIIEDMSPFGKRRKTASSRKMLDEGMMLEGFRRFDLYEDCKDAACQFSLKVTHY
HCTRENCGYKFCGRTHMYKHAQHHDRVDNLVLDDFKRFKASLSCHFADCPFSGTSTHFHCLRCRFRCTDSTKVTAHRKHHGKQDVISAAG
FCQFSSSADCAVPDCKYKLKCSHFHCTFPGCRHTVVGMSQMDSHKRKHEKQERGEPAAEGPAPGPPISLDGSLSLGAEPGSLLFLQSAAA
GLGLALGDAGDPGPPDAAAPGPREGAAAAAAAAGESSQEDEEEELELPEEEAEDDEDEDDDEDDDDEDDDEDDDDEDLRTDSEESLPEAA

>In-frame_OBSCN_ENST00000570156_chr1_228412435_+_CASZ1_ENST00000344008_chr1_10725628_-_2230aa
MDQPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCRARNAIGE
AFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGG
TYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETV
WKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLCEVPQPS
TEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETPEGSRTVAELAVQGNLLRKLPRKTAVRVGDTAMFCVELAVPVGP
VHWLRNQEEVVAGGRVAISAEGTRHTLTISQCCLEDVGQVAFMAGDCQTSTQFCVSAPRKPPLQPPVDPVVKARMESSVILSWSPPPHGE
RPVTIDGYLVEKKKLGTYTWIRCHEAEWVATPELTVADVAEEGNFQFRVSALNSFGQSPYLEFPGTVHLAPKLAVRTPLKAVQAVEGGEV
TFSVDLTVASAGEWFLDGQALKASSVYEIHCDRTRHTLTIREVPASLHGAQLKFVANGIESSIRMEVRAAPGLTANKPPAAAAREVLARL
HEEAQLLAELSDQAAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSRGGRIAYQLSVQGLARFLHKDMAGSCVDAV
AGGPAQFECETSEAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEGTYSCRVGEDSVDFRLRVSEPKAVFAKEQPACREV
QAEVGASATLSCEVAQDQMEVTWYKDGKKLSSSSKVHVEAVGCMRRLVVQQVGQADSGEYSCEARGQRVSFRLDVAEPKVVFAKEQLARR
KLQAEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEAGGQRLSFHLDVKAEGTRCTDPPAG
KPAMAPKRKGGLKLNAICAKLSRQVVVEKRADAGSHTEGSPSQPRDQERSGPESGAARAPRSEEDKRRAVIEKWVNGEYSEEPAPTPVLG
RIAREGLELPPEGVYMVQPQGCSDEEDHAEEPSKDGGALEEKDSDGAASKEDSGPSTRQASGEASSLRDYAASTMTEFLGMFGYDDQNTR
DELARKISFEKLHAGSTPEAATSSMLPTSEDTLSKRARFSKYEEYIRKLKAGEQLSWPAPSTKTEERVGKEVVGTLPGLRLPSSTAHLET
KATILPLPSHSSVQMQNLVARASKYDFFIQKLKTGENLRPQNGSTYKKPSKYDLENVKYLHLFKPGEGSPDMGGAIAFKTGKVGRPSKYD
VRGIQKPGPAKVPPTPSLAPAPLASVPSAPSAPGPGPEPPASLSFNTPEYLKSTFSKTDSITTGTVSTVKNGLPTDKPAVTEDVNIYQKY
IARFSGSQHCGHIHCAYQYREHYHCLDPECNYQRFTSKQDVIRHYNMHKKRDNSLQHGFMRFSPLDDCSVYYHGCHLNGKSTHYHCMQVG
CNKVYTSTSDVMTHENFHKKNTQLINDGFQRFRATEDCGTADCQFYGQKTTHFHCRRPGCTFTFKNKCDIEKHKSYHIKDDAYAKDGFKK
FYKYEECKYEGCVYSKATNHFHCIRAGCGFTFTSTSQMTSHKRKHERRHIRSSGALGLPPSLLGAKDTEHEESSNDDLVDFSALSSKNSS
LSASPTSQQSSASLAAATAATEAGPSATKPPNSKISGLLPQGLPGSIPLALALSNSGLPTPTPYFPILAGRGSTSLPVGTPSLLGAVSSG
SAASATPDTPTLVASGAGDSAPVAAASVPAPPASIMERISASKGLISPMMARLAAAALKPSATFDPGSGQQVTPARFPPAQVKPEPGEST
GAPGPHEASQDRSLDLTVKEPSNESNGHAVPANSSLLSSLMNKMSQGNPGLGSLLNIKAEAEGSPAAEPSPFLGKAVKALVQEKLAEPWK
VYLRRFGTKDFCDGQCDFLHKAHFHCVVEECGALFSTLDGAIKHANFHFRTEGGAAKGNTEAAFPASAAETKPPMAPSSPPVPPVTTATV

>In-frame_OBSCN_ENST00000422127_chr1_228412435_+_CASZ1_ENST00000377022_chr1_10725628_-_2731aa
MDQPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCRARNAIGE
AFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGG
TYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETV
WKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLCEVPQPS
TEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETPEGSRTVAELAVQGNLLRKLPRKTAVRVGDTAMFCVELAVPVGP
VHWLRNQEEVVAGGRVAISAEGTRHTLTISQCCLEDVGQVAFMAGDCQTSTQFCVSAPRKPPLQPPVDPVVKARMESSVILSWSPPPHGE
RPVTIDGYLVEKKKLGTYTWIRCHEAEWVATPELTVADVAEEGNFQFRVSALNSFGQSPYLEFPGTVHLAPKLAVRTPLKAVQAVEGGEV
TFSVDLTVASAGEWFLDGQALKASSVYEIHCDRTRHTLTIREVPASLHGAQLKFVANGIESSIRMEVRAAPGLTANKPPAAAAREVLARL
HEEAQLLAELSDQAAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSRGGRIAYQLSVQGLARFLHKDMAGSCVDAV
AGGPAQFECETSEAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEGTYSCRVGEDSVDFRLRVSEPKVVFAKEQLARRKL
QAEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEAGGQRLSFHLDVKAEGTRCTDPPAGKP
AMAPKRKGGLKLNAICAKLSRQVVVEKRADAGSHTEGSPSQPRDQERSGPESGAARAPRSEEDKRRAVIEKWVNGEYSEEPAPTPVLGRI
AREGLELPPEGVYMVQPQGCSDEEDHAEEPSKDGGALEEKDSDGAASKEDSGPSTRQASGEASSLRDYAASTMTEFLGMFGYDDQNTRDE
LARKISFEKLHAGSTPEAATSSMLPTSEDTLSKRARFSKYEEYIRKLKAGEQLSWPAPSTKTEERVGKEVVGTLPGLRLPSSTAHLETKA
TILPLPSHSSVQMQNLVARASKYDFFIQKLKTGENLRPQNGSTYKKPSKYDLENVKYLHLFKPGEGSPDMGGAIAFKTGKVGRPSKYDVR
GIQKPGPAKVPPTPSLAPAPLASVPSAPSAPGPGPEPPASLSFNTPEYLKSTFSKTDSITTGTVSTVKNGLPTDKPAVTEDVNIYQKYIA
RFSGSQHCGHIHCAYQYREHYHCLDPECNYQRFTSKQDVIRHYNMHKKRDNSLQHGFMRFSPLDDCSVYYHGCHLNGKSTHYHCMQVGCN
KVYTSTSDVMTHENFHKKNTQLINDGFQRFRATEDCGTADCQFYGQKTTHFHCRRPGCTFTFKNKCDIEKHKSYHIKDDAYAKDGFKKFY
KYEECKYEGCVYSKATNHFHCIRAGCGFTFTSTSQMTSHKRKHERRHIRSSGALGLPPSLLGAKDTEHEESSNDDLVDFSALSSKNSSLS
ASPTSQQSSASLAAATAATEAGPSATKPPNSKISGLLPQGLPGSIPLALALSNSGLPTPTPYFPILAGRGSTSLPVGTPSLLGAVSSGSA
ASATPDTPTLVASGAGDSAPVAAASVPAPPASIMERISASKGLISPMMARLAAAALKPSATFDPGSGQQVTPARFPPAQVKPEPGESTGA
PGPHEASQDRSLDLTVKEPSNESNGHAVPANSSLLSSLMNKMSQGNPGLGSLLNIKAEAEGSPAAEPSPFLGKAVKALVQEKLAEPWKVY
LRRFGTKDFCDGQCDFLHKAHFHCVVEECGALFSTLDGAIKHANFHFRTEGGAAKGNTEAAFPASAAETKPPMAPSSPPVPPVTTATVSS
LEGPAPSPASVPSTPTLLAWKQLASTIPQMPQIPASVPHLPASPLATTSLENAKPQVKPGFLQFQENDPCLATDCKYANKFHFHCLFGNC
KYVCKTSGKAESHCLDHINPNNNLVNVRDQFAYYSLQCLCPNQHCEFRMRGHYHCLRTGCYFVTNITTKLPWHIKKHEKAERRAANGFKY
FTKREECGRLGCKYNQVNSHFHCIREGCQFSFLLKHQMTSHARKHMRRMLGKNFDRVPPSQGPPGLMDAETDECMDYTGCSPGAMSSESS
TMDRSCSSTPVGNESTAAGNTISMPTASGAKKRFWIIEDMSPFGKRRKTASSRKMLDEGMMLEGFRRFDLYEDCKDAACQFSLKVTHYHC
TRENCGYKFCGRTHMYKHAQHHDRVDNLVLDDFKRFKASLSCHFADCPFSGTSTHFHCLRCRFRCTDSTKVTAHRKHHGKQDVISAAGFC
QFSSSADCAVPDCKYKLKCSHFHCTFPGCRHTVVGMSQMDSHKRKHEKQERGEPAAEGPAPGPPISLDGSLSLGAEPGSLLFLQSAAAGL
GLALGDAGDPGPPDAAAPGPREGAAAAAAAAGESSQEDEEEELELPEEEAEDDEDEDDDEDDDDEDDDEDDDDEDLRTDSEESLPEAAAE

>In-frame_OBSCN_ENST00000422127_chr1_228412435_+_CASZ1_ENST00000344008_chr1_10725628_-_2138aa
MDQPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCRARNAIGE
AFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGG
TYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETV
WKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLCEVPQPS
TEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETPEGSRTVAELAVQGNLLRKLPRKTAVRVGDTAMFCVELAVPVGP
VHWLRNQEEVVAGGRVAISAEGTRHTLTISQCCLEDVGQVAFMAGDCQTSTQFCVSAPRKPPLQPPVDPVVKARMESSVILSWSPPPHGE
RPVTIDGYLVEKKKLGTYTWIRCHEAEWVATPELTVADVAEEGNFQFRVSALNSFGQSPYLEFPGTVHLAPKLAVRTPLKAVQAVEGGEV
TFSVDLTVASAGEWFLDGQALKASSVYEIHCDRTRHTLTIREVPASLHGAQLKFVANGIESSIRMEVRAAPGLTANKPPAAAAREVLARL
HEEAQLLAELSDQAAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSRGGRIAYQLSVQGLARFLHKDMAGSCVDAV
AGGPAQFECETSEAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVAATVTRQDEGTYSCRVGEDSVDFRLRVSEPKVVFAKEQLARRKL
QAEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEAGGQRLSFHLDVKAEGTRCTDPPAGKP
AMAPKRKGGLKLNAICAKLSRQVVVEKRADAGSHTEGSPSQPRDQERSGPESGAARAPRSEEDKRRAVIEKWVNGEYSEEPAPTPVLGRI
AREGLELPPEGVYMVQPQGCSDEEDHAEEPSKDGGALEEKDSDGAASKEDSGPSTRQASGEASSLRDYAASTMTEFLGMFGYDDQNTRDE
LARKISFEKLHAGSTPEAATSSMLPTSEDTLSKRARFSKYEEYIRKLKAGEQLSWPAPSTKTEERVGKEVVGTLPGLRLPSSTAHLETKA
TILPLPSHSSVQMQNLVARASKYDFFIQKLKTGENLRPQNGSTYKKPSKYDLENVKYLHLFKPGEGSPDMGGAIAFKTGKVGRPSKYDVR
GIQKPGPAKVPPTPSLAPAPLASVPSAPSAPGPGPEPPASLSFNTPEYLKSTFSKTDSITTGTVSTVKNGLPTDKPAVTEDVNIYQKYIA
RFSGSQHCGHIHCAYQYREHYHCLDPECNYQRFTSKQDVIRHYNMHKKRDNSLQHGFMRFSPLDDCSVYYHGCHLNGKSTHYHCMQVGCN
KVYTSTSDVMTHENFHKKNTQLINDGFQRFRATEDCGTADCQFYGQKTTHFHCRRPGCTFTFKNKCDIEKHKSYHIKDDAYAKDGFKKFY
KYEECKYEGCVYSKATNHFHCIRAGCGFTFTSTSQMTSHKRKHERRHIRSSGALGLPPSLLGAKDTEHEESSNDDLVDFSALSSKNSSLS
ASPTSQQSSASLAAATAATEAGPSATKPPNSKISGLLPQGLPGSIPLALALSNSGLPTPTPYFPILAGRGSTSLPVGTPSLLGAVSSGSA
ASATPDTPTLVASGAGDSAPVAAASVPAPPASIMERISASKGLISPMMARLAAAALKPSATFDPGSGQQVTPARFPPAQVKPEPGESTGA
PGPHEASQDRSLDLTVKEPSNESNGHAVPANSSLLSSLMNKMSQGNPGLGSLLNIKAEAEGSPAAEPSPFLGKAVKALVQEKLAEPWKVY
LRRFGTKDFCDGQCDFLHKAHFHCVVEECGALFSTLDGAIKHANFHFRTEGGAAKGNTEAAFPASAAETKPPMAPSSPPVPPVTTATVSS


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_OBSCN_ENST00000284548_chr1_228412435_+_CASZ1_ENST00000377022_chr1_10725628_-_8193nt
ATGGATCAGCCACAGTTCAGCGGGGCGCCCCGCTTTCTCACCCGGCCCAAGGCCTTCGTGGTGTCGGTGGGCAAGGACGCCACCCTCAGC
TGCCAGATCGTGGGTAATCCCACGCCACAGGTGAGCTGGGAGAAGGACCAGCAGCCGGTGGCGGCCGGCGCGCGCTTCCGTCTGGCCCAG
GACGGCGACCTCTACCGCCTCACTATCCTGGACCTGGCGCTGGGCGACAGTGGGCAATACGTGTGCCGCGCGCGCAATGCCATAGGCGAG
GCCTTCGCTGCTGTGGGCCTGCAGGTGGACGCGGAGGCCGCGTGCGCCGAGCAGGCGCCGCACTTCCTGCTGCGGCCCACGTCCATCCGC
GTGCGCGAGGGCTCAGAGGCCACCTTCCGCTGCCGCGTGGGTGGCTCCCCGAGGCCGGCAGTGAGCTGGTCCAAGGACGGGCGGCGCCTG
GGTGAGCCCGACGGCCCCCGCGTGCGCGTGGAGGAGCTCGGCGAGGCAAGTGCGCTGCGCATTCGGGCGGCGCGGCCGCGCGACGGCGGC
ACTTACGAGGTCCGCGCCGAGAACCCGCTGGGCGCTGCCAGCGCCGCCGCGGCGCTAGTGGTGGACTCGGACGCCGCGGACACGGCCAGC
CGGCCCGGGACCTCCACGGCCGCGCTCCTGGCGCACCTGCAGCGGCGGCGCGAGGCTATGCGCGCCGAGGGCGCCCCCGCCTCACCGCCC
AGCACCGGCACGCGCACCTGCACGGTGACTGAAGGCAAGCACGCGCGCCTCAGCTGCTACGTGACCGGCGAGCCCAAGCCCGAGACGGTG
TGGAAGAAGGACGGCCAGCTGGTGACCGAGGGCCGGCGCCACGTGGTGTACGAGGACGCGCAGGAGAACTTCGTGCTCAAGATCCTCTTC
TGCAAGCAGTCGGACCGCGGCCTCTACACCTGCACGGCGTCCAACCTCGTGGGCCAGACCTACAGCTCTGTGCTGGTCGTAGTGCGCGAG
CCCGCGGTTCCCTTCAAAAAGCGGCTGCAAGATCTGGAGGTGCGGGAGAAGGAGTCGGCCACGTTCCTATGTGAGGTGCCCCAGCCGTCC
ACTGAGGCCGCGTGGTTCAAGGAGGAGACGCGGTTGTGGGCGAGCGCCAAGTACGGCATCGAGGAGGAGGGCACCGAGCGCCGCCTGACC
GTGCGCAATGTCTCGGCCGACGACGACGCGGTGTACATCTGCGAGACGCCAGAGGGCAGCCGCACGGTGGCGGAGCTCGCAGTCCAAGGA
AACCTCCTCCGAAAGCTCCCTCGGAAGACGGCGGTGCGCGTGGGCGACACGGCTATGTTTTGCGTGGAGCTGGCGGTCCCGGTGGGCCCC
GTCCACTGGCTGCGGAACCAGGAGGAAGTGGTGGCGGGGGGCCGCGTGGCCATCTCCGCGGAGGGCACGCGCCACACACTAACCATCTCC
CAGTGCTGCCTGGAGGATGTGGGCCAGGTGGCCTTTATGGCTGGCGACTGCCAGACGTCCACCCAGTTCTGCGTGTCGGCCCCCAGGAAG
CCTCCCCTGCAACCCCCTGTGGATCCTGTGGTAAAGGCCAGGATGGAGAGTTCCGTGATTCTCAGCTGGTCCCCACCACCCCATGGGGAA
CGCCCTGTCACTATCGACGGCTACCTGGTAGAGAAGAAGAAGCTTGGCACCTACACCTGGATCAGGTGCCACGAGGCTGAATGGGTGGCT
ACACCTGAGCTGACCGTGGCTGATGTGGCGGAGGAGGGGAACTTCCAGTTCCGAGTGTCCGCTCTCAACAGCTTTGGTCAGAGTCCCTAC
CTCGAGTTCCCGGGGACTGTCCACCTGGCCCCCAAGCTGGCCGTGAGGACACCGCTGAAGGCGGTGCAGGCGGTAGAGGGTGGCGAGGTC
ACTTTCTCCGTGGACCTCACGGTGGCCTCAGCGGGTGAGTGGTTCCTGGATGGGCAGGCCCTGAAGGCCAGCAGTGTGTATGAGATCCAC
TGTGATCGCACCCGGCACACGCTCACCATCCGGGAGGTGCCCGCCAGCCTGCACGGGGCGCAGCTGAAGTTCGTGGCCAACGGCATTGAG
AGCAGCATCCGGATGGAGGTCCGGGCGGCCCCAGGGCTGACTGCCAACAAGCCGCCAGCCGCAGCTGCCCGGGAGGTGCTGGCTCGGCTG
CACGAGGAGGCGCAGCTGCTGGCTGAGCTGTCAGATCAGGCTGCGGCTGTGACGTGGCTGAAGGATGGTCGCACACTGTCCCCAGGCCCC
AAGTATGAGGTGCAGGCATCGGCCGGGCGGCGGGTGCTCCTTGTGCGAGATGTGGCCCGGGACGATGCAGGCCTCTACGAGTGCGTCAGC
CGCGGGGGCCGCATCGCCTACCAGCTCTCCGTGCAAGGCCTCGCGCGCTTTCTGCACAAGGACATGGCGGGCAGCTGTGTGGATGCCGTG
GCTGGGGGCCCGGCGCAGTTTGAGTGTGAGACCTCCGAAGCCCACGTCCACGTGCACTGGTACAAGGATGGCATGGAGCTGGGCCACTCC
GGTGAGCGCTTCTTGCAGGAGGATGTGGGGACGCGGCACCGGCTGGTGGCAGCCACAGTCACCAGGCAGGATGAAGGCACCTACTCCTGC
CGCGTGGGCGAGGACTCTGTGGACTTCCGGCTCCGCGTCTCTGAGCCCAAGGTGGTGTTTGCTAAGGAGCAGCTGGCACGCAGGAAGCTG
CAGGCAGAGGCAGGAGCCAGTGCCACACTGAGCTGCGAGGTGGCCCAGGCCCAGACGGAGGTGACGTGGTACAAGGATGGGAAGAAGCTG
AGCTCCAGCTCGAAAGTGTGCATGGAGGCCACAGGCTGCACGCGCAGGCTGGTTGTGCAGCAGGCAGGCCAGGCGGATGCCGGGGAGTAT
AGCTGCGAGGCTGGGGGCCAGCGGCTCTCCTTCCATCTGGATGTCAAAGCTGAGGGCACCCGGTGCACGGACCCGCCTGCAGGCAAGCCC
GCCATGGCGCCCAAACGCAAGGGTGGCCTGAAGCTGAACGCCATCTGCGCCAAGCTGAGCCGCCAGGTGGTGGTGGAGAAGCGAGCTGAC
GCCGGCTCCCACACGGAGGGCAGCCCATCGCAGCCCCGGGACCAAGAGCGCAGTGGCCCTGAGTCTGGGGCAGCCCGGGCCCCCCGCAGC
GAGGAAGACAAGAGACGGGCAGTGATCGAGAAGTGGGTGAACGGGGAGTACAGCGAGGAGCCGGCACCCACACCCGTGTTGGGGCGGATT
GCCCGCGAGGGCCTGGAGCTGCCTCCCGAGGGTGTCTACATGGTGCAGCCCCAGGGGTGCAGCGATGAGGAAGACCACGCGGAGGAGCCC
TCCAAGGACGGCGGTGCCCTGGAGGAGAAGGATTCGGACGGGGCAGCCTCCAAGGAGGACAGCGGCCCCAGCACCAGGCAGGCTTCAGGA
GAGGCCTCCTCGCTGCGGGACTACGCGGCCTCCACCATGACCGAGTTCCTCGGCATGTTTGGCTATGATGACCAGAACACGCGGGACGAG
CTGGCCAGGAAGATCAGCTTTGAGAAGCTGCACGCGGGCTCCACCCCGGAGGCAGCCACCTCCTCCATGCTGCCCACCTCCGAGGATACC
CTCAGCAAGCGGGCGCGGTTCTCTAAGTATGAGGAGTACATCCGCAAGCTCAAGGCTGGCGAGCAGCTCTCCTGGCCGGCCCCCAGCACC
AAGACCGAGGAGCGGGTGGGCAAGGAGGTGGTGGGCACCCTGCCCGGCCTGCGGCTGCCCAGCAGCACGGCCCACCTGGAGACCAAGGCC
ACCATCCTGCCCCTGCCGTCGCACAGCAGTGTCCAGATGCAGAACCTGGTAGCCCGGGCCTCCAAGTACGACTTCTTCATCCAAAAACTG
AAGACCGGCGAGAATCTGCGGCCCCAGAACGGGAGCACCTACAAGAAGCCATCCAAGTACGACCTGGAGAATGTCAAGTACCTGCACCTC
TTCAAACCCGGGGAGGGCAGCCCCGACATGGGCGGGGCCATCGCCTTCAAGACAGGCAAGGTGGGGCGCCCTTCCAAGTACGACGTCCGG
GGCATCCAGAAGCCAGGCCCCGCCAAGGTTCCGCCCACCCCCAGCCTGGCTCCCGCACCCCTCGCCAGCGTGCCCAGTGCCCCCAGCGCC
CCCGGGCCAGGGCCAGAGCCTCCTGCCTCCCTGTCCTTCAACACTCCCGAGTACCTGAAGTCAACCTTCTCCAAAACAGACTCCATCACC
ACGGGGACCGTCTCCACTGTCAAGAACGGACTGCCCACAGATAAACCAGCCGTCACTGAAGATGTAAACATTTACCAGAAATATATTGCC
AGGTTCTCGGGCAGCCAGCACTGTGGCCACATCCACTGTGCCTACCAGTACCGCGAGCACTACCACTGCCTTGACCCTGAGTGTAACTAC
CAGAGGTTCACGAGTAAGCAGGACGTGATCCGCCACTACAACATGCACAAGAAGCGCGACAACTCCCTGCAGCACGGCTTCATGCGTTTC
AGCCCGCTGGACGACTGCAGCGTCTACTACCACGGCTGCCACCTCAATGGGAAGAGCACCCACTATCACTGCATGCAGGTGGGCTGTAAC
AAGGTGTACACGAGCACGTCTGACGTGATGACCCACGAGAACTTCCACAAGAAGAATACCCAGCTCATTAACGACGGCTTCCAGCGCTTC
CGAGCCACCGAAGACTGTGGCACAGCCGACTGCCAGTTCTACGGACAGAAGACCACGCACTTCCACTGCAGGCGCCCCGGCTGCACATTC
ACTTTCAAGAACAAGTGTGACATCGAGAAGCACAAGAGCTACCACATCAAGGACGATGCCTACGCCAAGGACGGCTTCAAGAAGTTCTAC
AAGTACGAGGAGTGCAAGTACGAGGGCTGCGTGTACAGCAAGGCTACCAACCACTTCCACTGCATCCGCGCCGGCTGCGGCTTCACCTTC
ACCTCCACCAGCCAGATGACCTCTCACAAGCGCAAGCATGAGCGCCGGCACATCCGCTCCTCGGGCGCGCTGGGGCTGCCGCCCTCGCTG
CTGGGCGCCAAGGACACGGAGCACGAGGAGTCCAGCAACGACGACCTTGTTGACTTCTCCGCCCTGAGCAGCAAGAACTCCAGCCTGAGC
GCCTCCCCTACCAGCCAGCAGTCCTCTGCGTCCCTGGCTGCCGCCACTGCCGCCACCGAGGCTGGGCCCAGTGCCACCAAACCTCCCAAC
AGCAAGATCTCGGGGCTGCTGCCCCAGGGCCTGCCTGGCTCAATCCCCCTGGCCCTGGCCCTCTCCAACTCGGGCCTGCCCACCCCCACG
CCCTACTTCCCCATACTGGCTGGCCGTGGGAGCACCTCCCTGCCTGTGGGCACCCCCAGCCTCCTGGGTGCCGTGTCGTCTGGGTCAGCA
GCCTCAGCCACCCCTGACACACCCACGCTGGTCGCCTCGGGAGCTGGAGACTCAGCCCCCGTGGCTGCCGCCTCTGTCCCGGCACCACCC
GCCTCCATCATGGAGAGGATCTCTGCAAGCAAGGGCCTCATCTCGCCCATGATGGCCAGGCTGGCTGCAGCTGCCCTCAAGCCCTCTGCC
ACCTTTGACCCAGGAAGCGGGCAGCAGGTCACCCCAGCCAGGTTCCCCCCGGCCCAAGTGAAGCCGGAACCCGGTGAGAGCACCGGCGCC
CCAGGCCCCCACGAAGCCTCCCAGGACCGCAGTCTAGACCTGACTGTGAAGGAGCCCAGCAACGAATCAAATGGCCACGCAGTCCCGGCA
AATTCATCTCTTTTATCCTCGCTTATGAATAAGATGTCTCAGGGCAACCCTGGCCTGGGCAGCCTGCTGAACATCAAGGCGGAAGCGGAG
GGGAGCCCCGCTGCGGAGCCCTCGCCCTTCCTAGGCAAGGCCGTGAAGGCGCTGGTTCAGGAGAAGTTGGCAGAGCCCTGGAAGGTGTAC
CTGCGCAGGTTTGGTACAAAGGACTTCTGTGACGGCCAGTGTGACTTCCTCCACAAGGCCCACTTCCACTGCGTGGTGGAGGAATGCGGC
GCGCTCTTCAGCACCTTGGACGGGGCCATCAAGCACGCAAACTTCCACTTCCGGACAGAGGGAGGAGCAGCAAAAGGAAACACAGAGGCT
GCCTTTCCGGCCTCGGCCGCCGAGACCAAACCTCCCATGGCCCCCTCGTCCCCTCCGGTCCCTCCTGTCACCACGGCCACGGTGTCCTCT
CTGGAGGGGCCCGCTCCCAGCCCGGCCTCCGTGCCCTCCACCCCCACCCTGCTCGCCTGGAAGCAGCTGGCTTCCACCATACCCCAGATG
CCTCAGATCCCAGCGTCAGTGCCTCACCTGCCCGCCTCGCCCTTGGCAACGACTTCTCTAGAGAACGCCAAGCCCCAGGTCAAACCCGGA
TTCCTCCAGTTCCAGGAGAACGATCCTTGCCTCGCCACGGACTGCAAGTACGCCAACAAGTTCCACTTCCACTGTCTCTTTGGGAACTGC
AAGTACGTCTGCAAAACGTCTGGCAAGGCCGAATCCCACTGCCTGGACCACATCAACCCCAACAACAACCTGGTGAACGTGCGAGACCAG
TTTGCATACTACTCTCTGCAGTGTCTCTGTCCCAACCAGCACTGCGAGTTCCGAATGCGTGGGCACTACCACTGCCTCCGCACCGGCTGC
TATTTTGTGACCAACATCACCACCAAGCTCCCCTGGCACATCAAGAAGCATGAGAAGGCGGAGCGGCGGGCAGCCAATGGCTTCAAATAC
TTCACCAAGCGCGAGGAGTGTGGCAGGCTAGGTTGCAAGTACAACCAGGTGAACAGCCACTTCCACTGCATCCGGGAGGGCTGCCAGTTC
TCCTTCCTCCTCAAGCACCAGATGACCTCCCACGCGCGGAAGCACATGCGGAGGATGCTGGGGAAGAACTTCGACCGCGTGCCCCCCTCC
CAGGGCCCCCCAGGCCTGATGGATGCTGAGACAGATGAGTGCATGGACTACACTGGCTGCAGCCCAGGCGCCATGTCCTCTGAGTCATCC
ACCATGGACCGGAGCTGCTCCAGCACCCCCGTGGGTAACGAGAGCACCGCGGCAGGGAACACCATCTCTATGCCGACAGCCTCGGGGGCC
AAAAAGCGCTTCTGGATCATCGAGGACATGTCGCCCTTCGGCAAGCGGCGGAAGACGGCGTCCTCCCGGAAGATGCTGGACGAGGGCATG
ATGCTGGAGGGCTTCCGGCGCTTCGACCTTTACGAGGACTGCAAGGACGCAGCTTGTCAGTTCTCGCTCAAGGTCACCCACTACCACTGC
ACGCGCGAGAACTGCGGCTACAAGTTCTGCGGGCGCACGCACATGTACAAGCACGCGCAGCACCACGACCGCGTGGACAACCTGGTGCTG
GACGACTTCAAGCGCTTCAAGGCCTCACTCAGCTGCCACTTCGCCGACTGCCCCTTCTCGGGCACCAGCACGCACTTCCACTGCCTGCGC
TGCCGCTTCCGCTGCACCGACAGCACCAAGGTCACGGCGCATCGCAAGCACCACGGCAAACAGGACGTGATCAGCGCCGCGGGCTTCTGC
CAGTTCAGCTCCAGCGCCGACTGCGCCGTGCCCGACTGCAAGTACAAGCTCAAGTGCTCGCACTTCCACTGCACCTTCCCGGGCTGCCGC
CACACGGTGGTGGGCATGTCGCAGATGGACTCGCACAAGCGCAAGCACGAGAAGCAGGAGCGCGGCGAGCCCGCGGCAGAGGGCCCCGCG
CCCGGGCCTCCCATCAGTCTGGACGGCTCCCTGTCGCTGGGCGCCGAGCCGGGCTCGCTGCTCTTCCTGCAGTCGGCGGCCGCCGGCCTG
GGCCTGGCGCTGGGCGACGCGGGCGACCCCGGCCCGCCCGACGCCGCCGCCCCCGGGCCGCGCGAGGGCGCCGCCGCCGCCGCCGCCGCA
GCTGGGGAGTCCTCGCAGGAGGACGAGGAGGAGGAGCTGGAGCTGCCGGAGGAGGAGGCCGAAGACGACGAGGACGAGGACGACGACGAG
GACGACGACGACGAGGACGACGACGAGGACGACGACGACGAGGACCTGCGCACCGACTCGGAGGAGTCGCTGCCCGAGGCGGCGGCGGAG
GCGGCGGGCGCGGGCGCGCGGACCCCGGCCTTGGCGGCGCTGGCGGCCCTGGGCGCCCCCGGCCCCGCGCCCACTGCAGCCTCCTCGCCC

>In-frame_OBSCN_ENST00000284548_chr1_228412435_+_CASZ1_ENST00000344008_chr1_10725628_-_6414nt
ATGGATCAGCCACAGTTCAGCGGGGCGCCCCGCTTTCTCACCCGGCCCAAGGCCTTCGTGGTGTCGGTGGGCAAGGACGCCACCCTCAGC
TGCCAGATCGTGGGTAATCCCACGCCACAGGTGAGCTGGGAGAAGGACCAGCAGCCGGTGGCGGCCGGCGCGCGCTTCCGTCTGGCCCAG
GACGGCGACCTCTACCGCCTCACTATCCTGGACCTGGCGCTGGGCGACAGTGGGCAATACGTGTGCCGCGCGCGCAATGCCATAGGCGAG
GCCTTCGCTGCTGTGGGCCTGCAGGTGGACGCGGAGGCCGCGTGCGCCGAGCAGGCGCCGCACTTCCTGCTGCGGCCCACGTCCATCCGC
GTGCGCGAGGGCTCAGAGGCCACCTTCCGCTGCCGCGTGGGTGGCTCCCCGAGGCCGGCAGTGAGCTGGTCCAAGGACGGGCGGCGCCTG
GGTGAGCCCGACGGCCCCCGCGTGCGCGTGGAGGAGCTCGGCGAGGCAAGTGCGCTGCGCATTCGGGCGGCGCGGCCGCGCGACGGCGGC
ACTTACGAGGTCCGCGCCGAGAACCCGCTGGGCGCTGCCAGCGCCGCCGCGGCGCTAGTGGTGGACTCGGACGCCGCGGACACGGCCAGC
CGGCCCGGGACCTCCACGGCCGCGCTCCTGGCGCACCTGCAGCGGCGGCGCGAGGCTATGCGCGCCGAGGGCGCCCCCGCCTCACCGCCC
AGCACCGGCACGCGCACCTGCACGGTGACTGAAGGCAAGCACGCGCGCCTCAGCTGCTACGTGACCGGCGAGCCCAAGCCCGAGACGGTG
TGGAAGAAGGACGGCCAGCTGGTGACCGAGGGCCGGCGCCACGTGGTGTACGAGGACGCGCAGGAGAACTTCGTGCTCAAGATCCTCTTC
TGCAAGCAGTCGGACCGCGGCCTCTACACCTGCACGGCGTCCAACCTCGTGGGCCAGACCTACAGCTCTGTGCTGGTCGTAGTGCGCGAG
CCCGCGGTTCCCTTCAAAAAGCGGCTGCAAGATCTGGAGGTGCGGGAGAAGGAGTCGGCCACGTTCCTATGTGAGGTGCCCCAGCCGTCC
ACTGAGGCCGCGTGGTTCAAGGAGGAGACGCGGTTGTGGGCGAGCGCCAAGTACGGCATCGAGGAGGAGGGCACCGAGCGCCGCCTGACC
GTGCGCAATGTCTCGGCCGACGACGACGCGGTGTACATCTGCGAGACGCCAGAGGGCAGCCGCACGGTGGCGGAGCTCGCAGTCCAAGGA
AACCTCCTCCGAAAGCTCCCTCGGAAGACGGCGGTGCGCGTGGGCGACACGGCTATGTTTTGCGTGGAGCTGGCGGTCCCGGTGGGCCCC
GTCCACTGGCTGCGGAACCAGGAGGAAGTGGTGGCGGGGGGCCGCGTGGCCATCTCCGCGGAGGGCACGCGCCACACACTAACCATCTCC
CAGTGCTGCCTGGAGGATGTGGGCCAGGTGGCCTTTATGGCTGGCGACTGCCAGACGTCCACCCAGTTCTGCGTGTCGGCCCCCAGGAAG
CCTCCCCTGCAACCCCCTGTGGATCCTGTGGTAAAGGCCAGGATGGAGAGTTCCGTGATTCTCAGCTGGTCCCCACCACCCCATGGGGAA
CGCCCTGTCACTATCGACGGCTACCTGGTAGAGAAGAAGAAGCTTGGCACCTACACCTGGATCAGGTGCCACGAGGCTGAATGGGTGGCT
ACACCTGAGCTGACCGTGGCTGATGTGGCGGAGGAGGGGAACTTCCAGTTCCGAGTGTCCGCTCTCAACAGCTTTGGTCAGAGTCCCTAC
CTCGAGTTCCCGGGGACTGTCCACCTGGCCCCCAAGCTGGCCGTGAGGACACCGCTGAAGGCGGTGCAGGCGGTAGAGGGTGGCGAGGTC
ACTTTCTCCGTGGACCTCACGGTGGCCTCAGCGGGTGAGTGGTTCCTGGATGGGCAGGCCCTGAAGGCCAGCAGTGTGTATGAGATCCAC
TGTGATCGCACCCGGCACACGCTCACCATCCGGGAGGTGCCCGCCAGCCTGCACGGGGCGCAGCTGAAGTTCGTGGCCAACGGCATTGAG
AGCAGCATCCGGATGGAGGTCCGGGCGGCCCCAGGGCTGACTGCCAACAAGCCGCCAGCCGCAGCTGCCCGGGAGGTGCTGGCTCGGCTG
CACGAGGAGGCGCAGCTGCTGGCTGAGCTGTCAGATCAGGCTGCGGCTGTGACGTGGCTGAAGGATGGTCGCACACTGTCCCCAGGCCCC
AAGTATGAGGTGCAGGCATCGGCCGGGCGGCGGGTGCTCCTTGTGCGAGATGTGGCCCGGGACGATGCAGGCCTCTACGAGTGCGTCAGC
CGCGGGGGCCGCATCGCCTACCAGCTCTCCGTGCAAGGCCTCGCGCGCTTTCTGCACAAGGACATGGCGGGCAGCTGTGTGGATGCCGTG
GCTGGGGGCCCGGCGCAGTTTGAGTGTGAGACCTCCGAAGCCCACGTCCACGTGCACTGGTACAAGGATGGCATGGAGCTGGGCCACTCC
GGTGAGCGCTTCTTGCAGGAGGATGTGGGGACGCGGCACCGGCTGGTGGCAGCCACAGTCACCAGGCAGGATGAAGGCACCTACTCCTGC
CGCGTGGGCGAGGACTCTGTGGACTTCCGGCTCCGCGTCTCTGAGCCCAAGGTGGTGTTTGCTAAGGAGCAGCTGGCACGCAGGAAGCTG
CAGGCAGAGGCAGGAGCCAGTGCCACACTGAGCTGCGAGGTGGCCCAGGCCCAGACGGAGGTGACGTGGTACAAGGATGGGAAGAAGCTG
AGCTCCAGCTCGAAAGTGTGCATGGAGGCCACAGGCTGCACGCGCAGGCTGGTTGTGCAGCAGGCAGGCCAGGCGGATGCCGGGGAGTAT
AGCTGCGAGGCTGGGGGCCAGCGGCTCTCCTTCCATCTGGATGTCAAAGCTGAGGGCACCCGGTGCACGGACCCGCCTGCAGGCAAGCCC
GCCATGGCGCCCAAACGCAAGGGTGGCCTGAAGCTGAACGCCATCTGCGCCAAGCTGAGCCGCCAGGTGGTGGTGGAGAAGCGAGCTGAC
GCCGGCTCCCACACGGAGGGCAGCCCATCGCAGCCCCGGGACCAAGAGCGCAGTGGCCCTGAGTCTGGGGCAGCCCGGGCCCCCCGCAGC
GAGGAAGACAAGAGACGGGCAGTGATCGAGAAGTGGGTGAACGGGGAGTACAGCGAGGAGCCGGCACCCACACCCGTGTTGGGGCGGATT
GCCCGCGAGGGCCTGGAGCTGCCTCCCGAGGGTGTCTACATGGTGCAGCCCCAGGGGTGCAGCGATGAGGAAGACCACGCGGAGGAGCCC
TCCAAGGACGGCGGTGCCCTGGAGGAGAAGGATTCGGACGGGGCAGCCTCCAAGGAGGACAGCGGCCCCAGCACCAGGCAGGCTTCAGGA
GAGGCCTCCTCGCTGCGGGACTACGCGGCCTCCACCATGACCGAGTTCCTCGGCATGTTTGGCTATGATGACCAGAACACGCGGGACGAG
CTGGCCAGGAAGATCAGCTTTGAGAAGCTGCACGCGGGCTCCACCCCGGAGGCAGCCACCTCCTCCATGCTGCCCACCTCCGAGGATACC
CTCAGCAAGCGGGCGCGGTTCTCTAAGTATGAGGAGTACATCCGCAAGCTCAAGGCTGGCGAGCAGCTCTCCTGGCCGGCCCCCAGCACC
AAGACCGAGGAGCGGGTGGGCAAGGAGGTGGTGGGCACCCTGCCCGGCCTGCGGCTGCCCAGCAGCACGGCCCACCTGGAGACCAAGGCC
ACCATCCTGCCCCTGCCGTCGCACAGCAGTGTCCAGATGCAGAACCTGGTAGCCCGGGCCTCCAAGTACGACTTCTTCATCCAAAAACTG
AAGACCGGCGAGAATCTGCGGCCCCAGAACGGGAGCACCTACAAGAAGCCATCCAAGTACGACCTGGAGAATGTCAAGTACCTGCACCTC
TTCAAACCCGGGGAGGGCAGCCCCGACATGGGCGGGGCCATCGCCTTCAAGACAGGCAAGGTGGGGCGCCCTTCCAAGTACGACGTCCGG
GGCATCCAGAAGCCAGGCCCCGCCAAGGTTCCGCCCACCCCCAGCCTGGCTCCCGCACCCCTCGCCAGCGTGCCCAGTGCCCCCAGCGCC
CCCGGGCCAGGGCCAGAGCCTCCTGCCTCCCTGTCCTTCAACACTCCCGAGTACCTGAAGTCAACCTTCTCCAAAACAGACTCCATCACC
ACGGGGACCGTCTCCACTGTCAAGAACGGACTGCCCACAGATAAACCAGCCGTCACTGAAGATGTAAACATTTACCAGAAATATATTGCC
AGGTTCTCGGGCAGCCAGCACTGTGGCCACATCCACTGTGCCTACCAGTACCGCGAGCACTACCACTGCCTTGACCCTGAGTGTAACTAC
CAGAGGTTCACGAGTAAGCAGGACGTGATCCGCCACTACAACATGCACAAGAAGCGCGACAACTCCCTGCAGCACGGCTTCATGCGTTTC
AGCCCGCTGGACGACTGCAGCGTCTACTACCACGGCTGCCACCTCAATGGGAAGAGCACCCACTATCACTGCATGCAGGTGGGCTGTAAC
AAGGTGTACACGAGCACGTCTGACGTGATGACCCACGAGAACTTCCACAAGAAGAATACCCAGCTCATTAACGACGGCTTCCAGCGCTTC
CGAGCCACCGAAGACTGTGGCACAGCCGACTGCCAGTTCTACGGACAGAAGACCACGCACTTCCACTGCAGGCGCCCCGGCTGCACATTC
ACTTTCAAGAACAAGTGTGACATCGAGAAGCACAAGAGCTACCACATCAAGGACGATGCCTACGCCAAGGACGGCTTCAAGAAGTTCTAC
AAGTACGAGGAGTGCAAGTACGAGGGCTGCGTGTACAGCAAGGCTACCAACCACTTCCACTGCATCCGCGCCGGCTGCGGCTTCACCTTC
ACCTCCACCAGCCAGATGACCTCTCACAAGCGCAAGCATGAGCGCCGGCACATCCGCTCCTCGGGCGCGCTGGGGCTGCCGCCCTCGCTG
CTGGGCGCCAAGGACACGGAGCACGAGGAGTCCAGCAACGACGACCTTGTTGACTTCTCCGCCCTGAGCAGCAAGAACTCCAGCCTGAGC
GCCTCCCCTACCAGCCAGCAGTCCTCTGCGTCCCTGGCTGCCGCCACTGCCGCCACCGAGGCTGGGCCCAGTGCCACCAAACCTCCCAAC
AGCAAGATCTCGGGGCTGCTGCCCCAGGGCCTGCCTGGCTCAATCCCCCTGGCCCTGGCCCTCTCCAACTCGGGCCTGCCCACCCCCACG
CCCTACTTCCCCATACTGGCTGGCCGTGGGAGCACCTCCCTGCCTGTGGGCACCCCCAGCCTCCTGGGTGCCGTGTCGTCTGGGTCAGCA
GCCTCAGCCACCCCTGACACACCCACGCTGGTCGCCTCGGGAGCTGGAGACTCAGCCCCCGTGGCTGCCGCCTCTGTCCCGGCACCACCC
GCCTCCATCATGGAGAGGATCTCTGCAAGCAAGGGCCTCATCTCGCCCATGATGGCCAGGCTGGCTGCAGCTGCCCTCAAGCCCTCTGCC
ACCTTTGACCCAGGAAGCGGGCAGCAGGTCACCCCAGCCAGGTTCCCCCCGGCCCAAGTGAAGCCGGAACCCGGTGAGAGCACCGGCGCC
CCAGGCCCCCACGAAGCCTCCCAGGACCGCAGTCTAGACCTGACTGTGAAGGAGCCCAGCAACGAATCAAATGGCCACGCAGTCCCGGCA
AATTCATCTCTTTTATCCTCGCTTATGAATAAGATGTCTCAGGGCAACCCTGGCCTGGGCAGCCTGCTGAACATCAAGGCGGAAGCGGAG
GGGAGCCCCGCTGCGGAGCCCTCGCCCTTCCTAGGCAAGGCCGTGAAGGCGCTGGTTCAGGAGAAGTTGGCAGAGCCCTGGAAGGTGTAC
CTGCGCAGGTTTGGTACAAAGGACTTCTGTGACGGCCAGTGTGACTTCCTCCACAAGGCCCACTTCCACTGCGTGGTGGAGGAATGCGGC
GCGCTCTTCAGCACCTTGGACGGGGCCATCAAGCACGCAAACTTCCACTTCCGGACAGAGGGAGGAGCAGCAAAAGGAAACACAGAGGCT
GCCTTTCCGGCCTCGGCCGCCGAGACCAAACCTCCCATGGCCCCCTCGTCCCCTCCGGTCCCTCCTGTCACCACGGCCACGGTGTCCTCT
CTGGAGGGGCCCGCTCCCAGCCCGGCCTCCGTGCCCTCCACCCCCACCCTGCTCGCCTGGAAGCAGCTGGCTTCCACCATACCCCAGATG
CCTCAGATCCCAGCGTCAGTGCCTCACCTGCCCGCCTCGCCCTTGGCAACGACTTCTCTAGAGAACGCCAAGCCCCAGGTCAAACCCGGA

>In-frame_OBSCN_ENST00000570156_chr1_228412435_+_CASZ1_ENST00000377022_chr1_10725628_-_8469nt
ATGGATCAGCCACAGTTCAGCGGGGCGCCCCGCTTTCTCACCCGGCCCAAGGCCTTCGTGGTGTCGGTGGGCAAGGACGCCACCCTCAGC
TGCCAGATCGTGGGTAATCCCACGCCACAGGTGAGCTGGGAGAAGGACCAGCAGCCGGTGGCGGCCGGCGCGCGCTTCCGTCTGGCCCAG
GACGGCGACCTCTACCGCCTCACTATCCTGGACCTGGCGCTGGGCGACAGTGGGCAATACGTGTGCCGCGCGCGCAATGCCATAGGCGAG
GCCTTCGCTGCTGTGGGCCTGCAGGTGGACGCGGAGGCCGCGTGCGCCGAGCAGGCGCCGCACTTCCTGCTGCGGCCCACGTCCATCCGC
GTGCGCGAGGGCTCAGAGGCCACCTTCCGCTGCCGCGTGGGTGGCTCCCCGAGGCCGGCAGTGAGCTGGTCCAAGGACGGGCGGCGCCTG
GGTGAGCCCGACGGCCCCCGCGTGCGCGTGGAGGAGCTCGGCGAGGCAAGTGCGCTGCGCATTCGGGCGGCGCGGCCGCGCGACGGCGGC
ACTTACGAGGTCCGCGCCGAGAACCCGCTGGGCGCTGCCAGCGCCGCCGCGGCGCTAGTGGTGGACTCGGACGCCGCGGACACGGCCAGC
CGGCCCGGGACCTCCACGGCCGCGCTCCTGGCGCACCTGCAGCGGCGGCGCGAGGCTATGCGCGCCGAGGGCGCCCCCGCCTCACCGCCC
AGCACCGGCACGCGCACCTGCACGGTGACTGAAGGCAAGCACGCGCGCCTCAGCTGCTACGTGACCGGCGAGCCCAAGCCCGAGACGGTG
TGGAAGAAGGACGGCCAGCTGGTGACCGAGGGCCGGCGCCACGTGGTGTACGAGGACGCGCAGGAGAACTTCGTGCTCAAGATCCTCTTC
TGCAAGCAGTCGGACCGCGGCCTCTACACCTGCACGGCGTCCAACCTCGTGGGCCAGACCTACAGCTCTGTGCTGGTCGTAGTGCGCGAG
CCCGCGGTTCCCTTCAAAAAGCGGCTGCAAGATCTGGAGGTGCGGGAGAAGGAGTCGGCCACGTTCCTATGTGAGGTGCCCCAGCCGTCC
ACTGAGGCCGCGTGGTTCAAGGAGGAGACGCGGTTGTGGGCGAGCGCCAAGTACGGCATCGAGGAGGAGGGCACCGAGCGCCGCCTGACC
GTGCGCAATGTCTCGGCCGACGACGACGCGGTGTACATCTGCGAGACGCCAGAGGGCAGCCGCACGGTGGCGGAGCTCGCAGTCCAAGGA
AACCTCCTCCGAAAGCTCCCTCGGAAGACGGCGGTGCGCGTGGGCGACACGGCTATGTTTTGCGTGGAGCTGGCGGTCCCGGTGGGCCCC
GTCCACTGGCTGCGGAACCAGGAGGAAGTGGTGGCGGGGGGCCGCGTGGCCATCTCCGCGGAGGGCACGCGCCACACACTAACCATCTCC
CAGTGCTGCCTGGAGGATGTGGGCCAGGTGGCCTTTATGGCTGGCGACTGCCAGACGTCCACCCAGTTCTGCGTGTCGGCCCCCAGGAAG
CCTCCCCTGCAACCCCCTGTGGATCCTGTGGTAAAGGCCAGGATGGAGAGTTCCGTGATTCTCAGCTGGTCCCCACCACCCCATGGGGAA
CGCCCTGTCACTATCGACGGCTACCTGGTAGAGAAGAAGAAGCTTGGCACCTACACCTGGATCAGGTGCCACGAGGCTGAATGGGTGGCT
ACACCTGAGCTGACCGTGGCTGATGTGGCGGAGGAGGGGAACTTCCAGTTCCGAGTGTCCGCTCTCAACAGCTTTGGTCAGAGTCCCTAC
CTCGAGTTCCCGGGGACTGTCCACCTGGCCCCCAAGCTGGCCGTGAGGACACCGCTGAAGGCGGTGCAGGCGGTAGAGGGTGGCGAGGTC
ACTTTCTCCGTGGACCTCACGGTGGCCTCAGCGGGTGAGTGGTTCCTGGATGGGCAGGCCCTGAAGGCCAGCAGTGTGTATGAGATCCAC
TGTGATCGCACCCGGCACACGCTCACCATCCGGGAGGTGCCCGCCAGCCTGCACGGGGCGCAGCTGAAGTTCGTGGCCAACGGCATTGAG
AGCAGCATCCGGATGGAGGTCCGGGCGGCCCCAGGGCTGACTGCCAACAAGCCGCCAGCCGCAGCTGCCCGGGAGGTGCTGGCTCGGCTG
CACGAGGAGGCGCAGCTGCTGGCTGAGCTGTCAGATCAGGCTGCGGCTGTGACGTGGCTGAAGGATGGTCGCACACTGTCCCCAGGCCCC
AAGTATGAGGTGCAGGCATCGGCCGGGCGGCGGGTGCTCCTTGTGCGAGATGTGGCCCGGGACGATGCAGGCCTCTACGAGTGCGTCAGC
CGCGGGGGCCGCATCGCCTACCAGCTCTCCGTGCAAGGCCTCGCGCGCTTTCTGCACAAGGACATGGCGGGCAGCTGTGTGGATGCCGTG
GCTGGGGGCCCGGCGCAGTTTGAGTGTGAGACCTCCGAAGCCCACGTCCACGTGCACTGGTACAAGGATGGCATGGAGCTGGGCCACTCC
GGTGAGCGCTTCTTGCAGGAGGATGTGGGGACGCGGCACCGGCTGGTGGCAGCCACAGTCACCAGGCAGGATGAAGGCACCTACTCCTGC
CGCGTGGGCGAGGACTCTGTGGACTTCCGGCTCCGCGTCTCTGAGCCCAAGGCGGTGTTTGCCAAGGAGCAGCCGGCGTGCAGGGAGGTG
CAGGCTGAGGTGGGGGCCAGCGCCACGCTGAGCTGTGAGGTGGCCCAGGACCAGATGGAGGTGACGTGGTACAAGGACGGGAAGAAGTTG
AGCTCCAGCTCGAAAGTGCACGTGGAGGCTGTGGGCTGTATGCGGAGGCTGGTGGTGCAGCAGGTGGGCCAGGCAGACTCCGGAGAGTAC
AGCTGTGAGGCCAGGGGACAGAGGGTCTCCTTCCGCCTGGACGTTGCAGAGCCCAAGGTGGTGTTTGCTAAGGAGCAGCTGGCACGCAGG
AAGCTGCAGGCAGAGGCAGGAGCCAGTGCCACACTGAGCTGCGAGGTGGCCCAGGCCCAGACGGAGGTGACGTGGTACAAGGATGGGAAG
AAGCTGAGCTCCAGCTCGAAAGTGTGCATGGAGGCCACAGGCTGCACGCGCAGGCTGGTTGTGCAGCAGGCAGGCCAGGCGGATGCCGGG
GAGTATAGCTGCGAGGCTGGGGGCCAGCGGCTCTCCTTCCATCTGGATGTCAAAGCTGAGGGCACCCGGTGCACGGACCCGCCTGCAGGC
AAGCCCGCCATGGCGCCCAAACGCAAGGGTGGCCTGAAGCTGAACGCCATCTGCGCCAAGCTGAGCCGCCAGGTGGTGGTGGAGAAGCGA
GCTGACGCCGGCTCCCACACGGAGGGCAGCCCATCGCAGCCCCGGGACCAAGAGCGCAGTGGCCCTGAGTCTGGGGCAGCCCGGGCCCCC
CGCAGCGAGGAAGACAAGAGACGGGCAGTGATCGAGAAGTGGGTGAACGGGGAGTACAGCGAGGAGCCGGCACCCACACCCGTGTTGGGG
CGGATTGCCCGCGAGGGCCTGGAGCTGCCTCCCGAGGGTGTCTACATGGTGCAGCCCCAGGGGTGCAGCGATGAGGAAGACCACGCGGAG
GAGCCCTCCAAGGACGGCGGTGCCCTGGAGGAGAAGGATTCGGACGGGGCAGCCTCCAAGGAGGACAGCGGCCCCAGCACCAGGCAGGCT
TCAGGAGAGGCCTCCTCGCTGCGGGACTACGCGGCCTCCACCATGACCGAGTTCCTCGGCATGTTTGGCTATGATGACCAGAACACGCGG
GACGAGCTGGCCAGGAAGATCAGCTTTGAGAAGCTGCACGCGGGCTCCACCCCGGAGGCAGCCACCTCCTCCATGCTGCCCACCTCCGAG
GATACCCTCAGCAAGCGGGCGCGGTTCTCTAAGTATGAGGAGTACATCCGCAAGCTCAAGGCTGGCGAGCAGCTCTCCTGGCCGGCCCCC
AGCACCAAGACCGAGGAGCGGGTGGGCAAGGAGGTGGTGGGCACCCTGCCCGGCCTGCGGCTGCCCAGCAGCACGGCCCACCTGGAGACC
AAGGCCACCATCCTGCCCCTGCCGTCGCACAGCAGTGTCCAGATGCAGAACCTGGTAGCCCGGGCCTCCAAGTACGACTTCTTCATCCAA
AAACTGAAGACCGGCGAGAATCTGCGGCCCCAGAACGGGAGCACCTACAAGAAGCCATCCAAGTACGACCTGGAGAATGTCAAGTACCTG
CACCTCTTCAAACCCGGGGAGGGCAGCCCCGACATGGGCGGGGCCATCGCCTTCAAGACAGGCAAGGTGGGGCGCCCTTCCAAGTACGAC
GTCCGGGGCATCCAGAAGCCAGGCCCCGCCAAGGTTCCGCCCACCCCCAGCCTGGCTCCCGCACCCCTCGCCAGCGTGCCCAGTGCCCCC
AGCGCCCCCGGGCCAGGGCCAGAGCCTCCTGCCTCCCTGTCCTTCAACACTCCCGAGTACCTGAAGTCAACCTTCTCCAAAACAGACTCC
ATCACCACGGGGACCGTCTCCACTGTCAAGAACGGACTGCCCACAGATAAACCAGCCGTCACTGAAGATGTAAACATTTACCAGAAATAT
ATTGCCAGGTTCTCGGGCAGCCAGCACTGTGGCCACATCCACTGTGCCTACCAGTACCGCGAGCACTACCACTGCCTTGACCCTGAGTGT
AACTACCAGAGGTTCACGAGTAAGCAGGACGTGATCCGCCACTACAACATGCACAAGAAGCGCGACAACTCCCTGCAGCACGGCTTCATG
CGTTTCAGCCCGCTGGACGACTGCAGCGTCTACTACCACGGCTGCCACCTCAATGGGAAGAGCACCCACTATCACTGCATGCAGGTGGGC
TGTAACAAGGTGTACACGAGCACGTCTGACGTGATGACCCACGAGAACTTCCACAAGAAGAATACCCAGCTCATTAACGACGGCTTCCAG
CGCTTCCGAGCCACCGAAGACTGTGGCACAGCCGACTGCCAGTTCTACGGACAGAAGACCACGCACTTCCACTGCAGGCGCCCCGGCTGC
ACATTCACTTTCAAGAACAAGTGTGACATCGAGAAGCACAAGAGCTACCACATCAAGGACGATGCCTACGCCAAGGACGGCTTCAAGAAG
TTCTACAAGTACGAGGAGTGCAAGTACGAGGGCTGCGTGTACAGCAAGGCTACCAACCACTTCCACTGCATCCGCGCCGGCTGCGGCTTC
ACCTTCACCTCCACCAGCCAGATGACCTCTCACAAGCGCAAGCATGAGCGCCGGCACATCCGCTCCTCGGGCGCGCTGGGGCTGCCGCCC
TCGCTGCTGGGCGCCAAGGACACGGAGCACGAGGAGTCCAGCAACGACGACCTTGTTGACTTCTCCGCCCTGAGCAGCAAGAACTCCAGC
CTGAGCGCCTCCCCTACCAGCCAGCAGTCCTCTGCGTCCCTGGCTGCCGCCACTGCCGCCACCGAGGCTGGGCCCAGTGCCACCAAACCT
CCCAACAGCAAGATCTCGGGGCTGCTGCCCCAGGGCCTGCCTGGCTCAATCCCCCTGGCCCTGGCCCTCTCCAACTCGGGCCTGCCCACC
CCCACGCCCTACTTCCCCATACTGGCTGGCCGTGGGAGCACCTCCCTGCCTGTGGGCACCCCCAGCCTCCTGGGTGCCGTGTCGTCTGGG
TCAGCAGCCTCAGCCACCCCTGACACACCCACGCTGGTCGCCTCGGGAGCTGGAGACTCAGCCCCCGTGGCTGCCGCCTCTGTCCCGGCA
CCACCCGCCTCCATCATGGAGAGGATCTCTGCAAGCAAGGGCCTCATCTCGCCCATGATGGCCAGGCTGGCTGCAGCTGCCCTCAAGCCC
TCTGCCACCTTTGACCCAGGAAGCGGGCAGCAGGTCACCCCAGCCAGGTTCCCCCCGGCCCAAGTGAAGCCGGAACCCGGTGAGAGCACC
GGCGCCCCAGGCCCCCACGAAGCCTCCCAGGACCGCAGTCTAGACCTGACTGTGAAGGAGCCCAGCAACGAATCAAATGGCCACGCAGTC
CCGGCAAATTCATCTCTTTTATCCTCGCTTATGAATAAGATGTCTCAGGGCAACCCTGGCCTGGGCAGCCTGCTGAACATCAAGGCGGAA
GCGGAGGGGAGCCCCGCTGCGGAGCCCTCGCCCTTCCTAGGCAAGGCCGTGAAGGCGCTGGTTCAGGAGAAGTTGGCAGAGCCCTGGAAG
GTGTACCTGCGCAGGTTTGGTACAAAGGACTTCTGTGACGGCCAGTGTGACTTCCTCCACAAGGCCCACTTCCACTGCGTGGTGGAGGAA
TGCGGCGCGCTCTTCAGCACCTTGGACGGGGCCATCAAGCACGCAAACTTCCACTTCCGGACAGAGGGAGGAGCAGCAAAAGGAAACACA
GAGGCTGCCTTTCCGGCCTCGGCCGCCGAGACCAAACCTCCCATGGCCCCCTCGTCCCCTCCGGTCCCTCCTGTCACCACGGCCACGGTG
TCCTCTCTGGAGGGGCCCGCTCCCAGCCCGGCCTCCGTGCCCTCCACCCCCACCCTGCTCGCCTGGAAGCAGCTGGCTTCCACCATACCC
CAGATGCCTCAGATCCCAGCGTCAGTGCCTCACCTGCCCGCCTCGCCCTTGGCAACGACTTCTCTAGAGAACGCCAAGCCCCAGGTCAAA
CCCGGATTCCTCCAGTTCCAGGAGAACGATCCTTGCCTCGCCACGGACTGCAAGTACGCCAACAAGTTCCACTTCCACTGTCTCTTTGGG
AACTGCAAGTACGTCTGCAAAACGTCTGGCAAGGCCGAATCCCACTGCCTGGACCACATCAACCCCAACAACAACCTGGTGAACGTGCGA
GACCAGTTTGCATACTACTCTCTGCAGTGTCTCTGTCCCAACCAGCACTGCGAGTTCCGAATGCGTGGGCACTACCACTGCCTCCGCACC
GGCTGCTATTTTGTGACCAACATCACCACCAAGCTCCCCTGGCACATCAAGAAGCATGAGAAGGCGGAGCGGCGGGCAGCCAATGGCTTC
AAATACTTCACCAAGCGCGAGGAGTGTGGCAGGCTAGGTTGCAAGTACAACCAGGTGAACAGCCACTTCCACTGCATCCGGGAGGGCTGC
CAGTTCTCCTTCCTCCTCAAGCACCAGATGACCTCCCACGCGCGGAAGCACATGCGGAGGATGCTGGGGAAGAACTTCGACCGCGTGCCC
CCCTCCCAGGGCCCCCCAGGCCTGATGGATGCTGAGACAGATGAGTGCATGGACTACACTGGCTGCAGCCCAGGCGCCATGTCCTCTGAG
TCATCCACCATGGACCGGAGCTGCTCCAGCACCCCCGTGGGTAACGAGAGCACCGCGGCAGGGAACACCATCTCTATGCCGACAGCCTCG
GGGGCCAAAAAGCGCTTCTGGATCATCGAGGACATGTCGCCCTTCGGCAAGCGGCGGAAGACGGCGTCCTCCCGGAAGATGCTGGACGAG
GGCATGATGCTGGAGGGCTTCCGGCGCTTCGACCTTTACGAGGACTGCAAGGACGCAGCTTGTCAGTTCTCGCTCAAGGTCACCCACTAC
CACTGCACGCGCGAGAACTGCGGCTACAAGTTCTGCGGGCGCACGCACATGTACAAGCACGCGCAGCACCACGACCGCGTGGACAACCTG
GTGCTGGACGACTTCAAGCGCTTCAAGGCCTCACTCAGCTGCCACTTCGCCGACTGCCCCTTCTCGGGCACCAGCACGCACTTCCACTGC
CTGCGCTGCCGCTTCCGCTGCACCGACAGCACCAAGGTCACGGCGCATCGCAAGCACCACGGCAAACAGGACGTGATCAGCGCCGCGGGC
TTCTGCCAGTTCAGCTCCAGCGCCGACTGCGCCGTGCCCGACTGCAAGTACAAGCTCAAGTGCTCGCACTTCCACTGCACCTTCCCGGGC
TGCCGCCACACGGTGGTGGGCATGTCGCAGATGGACTCGCACAAGCGCAAGCACGAGAAGCAGGAGCGCGGCGAGCCCGCGGCAGAGGGC
CCCGCGCCCGGGCCTCCCATCAGTCTGGACGGCTCCCTGTCGCTGGGCGCCGAGCCGGGCTCGCTGCTCTTCCTGCAGTCGGCGGCCGCC
GGCCTGGGCCTGGCGCTGGGCGACGCGGGCGACCCCGGCCCGCCCGACGCCGCCGCCCCCGGGCCGCGCGAGGGCGCCGCCGCCGCCGCC
GCCGCAGCTGGGGAGTCCTCGCAGGAGGACGAGGAGGAGGAGCTGGAGCTGCCGGAGGAGGAGGCCGAAGACGACGAGGACGAGGACGAC
GACGAGGACGACGACGACGAGGACGACGACGAGGACGACGACGACGAGGACCTGCGCACCGACTCGGAGGAGTCGCTGCCCGAGGCGGCG
GCGGAGGCGGCGGGCGCGGGCGCGCGGACCCCGGCCTTGGCGGCGCTGGCGGCCCTGGGCGCCCCCGGCCCCGCGCCCACTGCAGCCTCC

>In-frame_OBSCN_ENST00000570156_chr1_228412435_+_CASZ1_ENST00000344008_chr1_10725628_-_6690nt
ATGGATCAGCCACAGTTCAGCGGGGCGCCCCGCTTTCTCACCCGGCCCAAGGCCTTCGTGGTGTCGGTGGGCAAGGACGCCACCCTCAGC
TGCCAGATCGTGGGTAATCCCACGCCACAGGTGAGCTGGGAGAAGGACCAGCAGCCGGTGGCGGCCGGCGCGCGCTTCCGTCTGGCCCAG
GACGGCGACCTCTACCGCCTCACTATCCTGGACCTGGCGCTGGGCGACAGTGGGCAATACGTGTGCCGCGCGCGCAATGCCATAGGCGAG
GCCTTCGCTGCTGTGGGCCTGCAGGTGGACGCGGAGGCCGCGTGCGCCGAGCAGGCGCCGCACTTCCTGCTGCGGCCCACGTCCATCCGC
GTGCGCGAGGGCTCAGAGGCCACCTTCCGCTGCCGCGTGGGTGGCTCCCCGAGGCCGGCAGTGAGCTGGTCCAAGGACGGGCGGCGCCTG
GGTGAGCCCGACGGCCCCCGCGTGCGCGTGGAGGAGCTCGGCGAGGCAAGTGCGCTGCGCATTCGGGCGGCGCGGCCGCGCGACGGCGGC
ACTTACGAGGTCCGCGCCGAGAACCCGCTGGGCGCTGCCAGCGCCGCCGCGGCGCTAGTGGTGGACTCGGACGCCGCGGACACGGCCAGC
CGGCCCGGGACCTCCACGGCCGCGCTCCTGGCGCACCTGCAGCGGCGGCGCGAGGCTATGCGCGCCGAGGGCGCCCCCGCCTCACCGCCC
AGCACCGGCACGCGCACCTGCACGGTGACTGAAGGCAAGCACGCGCGCCTCAGCTGCTACGTGACCGGCGAGCCCAAGCCCGAGACGGTG
TGGAAGAAGGACGGCCAGCTGGTGACCGAGGGCCGGCGCCACGTGGTGTACGAGGACGCGCAGGAGAACTTCGTGCTCAAGATCCTCTTC
TGCAAGCAGTCGGACCGCGGCCTCTACACCTGCACGGCGTCCAACCTCGTGGGCCAGACCTACAGCTCTGTGCTGGTCGTAGTGCGCGAG
CCCGCGGTTCCCTTCAAAAAGCGGCTGCAAGATCTGGAGGTGCGGGAGAAGGAGTCGGCCACGTTCCTATGTGAGGTGCCCCAGCCGTCC
ACTGAGGCCGCGTGGTTCAAGGAGGAGACGCGGTTGTGGGCGAGCGCCAAGTACGGCATCGAGGAGGAGGGCACCGAGCGCCGCCTGACC
GTGCGCAATGTCTCGGCCGACGACGACGCGGTGTACATCTGCGAGACGCCAGAGGGCAGCCGCACGGTGGCGGAGCTCGCAGTCCAAGGA
AACCTCCTCCGAAAGCTCCCTCGGAAGACGGCGGTGCGCGTGGGCGACACGGCTATGTTTTGCGTGGAGCTGGCGGTCCCGGTGGGCCCC
GTCCACTGGCTGCGGAACCAGGAGGAAGTGGTGGCGGGGGGCCGCGTGGCCATCTCCGCGGAGGGCACGCGCCACACACTAACCATCTCC
CAGTGCTGCCTGGAGGATGTGGGCCAGGTGGCCTTTATGGCTGGCGACTGCCAGACGTCCACCCAGTTCTGCGTGTCGGCCCCCAGGAAG
CCTCCCCTGCAACCCCCTGTGGATCCTGTGGTAAAGGCCAGGATGGAGAGTTCCGTGATTCTCAGCTGGTCCCCACCACCCCATGGGGAA
CGCCCTGTCACTATCGACGGCTACCTGGTAGAGAAGAAGAAGCTTGGCACCTACACCTGGATCAGGTGCCACGAGGCTGAATGGGTGGCT
ACACCTGAGCTGACCGTGGCTGATGTGGCGGAGGAGGGGAACTTCCAGTTCCGAGTGTCCGCTCTCAACAGCTTTGGTCAGAGTCCCTAC
CTCGAGTTCCCGGGGACTGTCCACCTGGCCCCCAAGCTGGCCGTGAGGACACCGCTGAAGGCGGTGCAGGCGGTAGAGGGTGGCGAGGTC
ACTTTCTCCGTGGACCTCACGGTGGCCTCAGCGGGTGAGTGGTTCCTGGATGGGCAGGCCCTGAAGGCCAGCAGTGTGTATGAGATCCAC
TGTGATCGCACCCGGCACACGCTCACCATCCGGGAGGTGCCCGCCAGCCTGCACGGGGCGCAGCTGAAGTTCGTGGCCAACGGCATTGAG
AGCAGCATCCGGATGGAGGTCCGGGCGGCCCCAGGGCTGACTGCCAACAAGCCGCCAGCCGCAGCTGCCCGGGAGGTGCTGGCTCGGCTG
CACGAGGAGGCGCAGCTGCTGGCTGAGCTGTCAGATCAGGCTGCGGCTGTGACGTGGCTGAAGGATGGTCGCACACTGTCCCCAGGCCCC
AAGTATGAGGTGCAGGCATCGGCCGGGCGGCGGGTGCTCCTTGTGCGAGATGTGGCCCGGGACGATGCAGGCCTCTACGAGTGCGTCAGC
CGCGGGGGCCGCATCGCCTACCAGCTCTCCGTGCAAGGCCTCGCGCGCTTTCTGCACAAGGACATGGCGGGCAGCTGTGTGGATGCCGTG
GCTGGGGGCCCGGCGCAGTTTGAGTGTGAGACCTCCGAAGCCCACGTCCACGTGCACTGGTACAAGGATGGCATGGAGCTGGGCCACTCC
GGTGAGCGCTTCTTGCAGGAGGATGTGGGGACGCGGCACCGGCTGGTGGCAGCCACAGTCACCAGGCAGGATGAAGGCACCTACTCCTGC
CGCGTGGGCGAGGACTCTGTGGACTTCCGGCTCCGCGTCTCTGAGCCCAAGGCGGTGTTTGCCAAGGAGCAGCCGGCGTGCAGGGAGGTG
CAGGCTGAGGTGGGGGCCAGCGCCACGCTGAGCTGTGAGGTGGCCCAGGACCAGATGGAGGTGACGTGGTACAAGGACGGGAAGAAGTTG
AGCTCCAGCTCGAAAGTGCACGTGGAGGCTGTGGGCTGTATGCGGAGGCTGGTGGTGCAGCAGGTGGGCCAGGCAGACTCCGGAGAGTAC
AGCTGTGAGGCCAGGGGACAGAGGGTCTCCTTCCGCCTGGACGTTGCAGAGCCCAAGGTGGTGTTTGCTAAGGAGCAGCTGGCACGCAGG
AAGCTGCAGGCAGAGGCAGGAGCCAGTGCCACACTGAGCTGCGAGGTGGCCCAGGCCCAGACGGAGGTGACGTGGTACAAGGATGGGAAG
AAGCTGAGCTCCAGCTCGAAAGTGTGCATGGAGGCCACAGGCTGCACGCGCAGGCTGGTTGTGCAGCAGGCAGGCCAGGCGGATGCCGGG
GAGTATAGCTGCGAGGCTGGGGGCCAGCGGCTCTCCTTCCATCTGGATGTCAAAGCTGAGGGCACCCGGTGCACGGACCCGCCTGCAGGC
AAGCCCGCCATGGCGCCCAAACGCAAGGGTGGCCTGAAGCTGAACGCCATCTGCGCCAAGCTGAGCCGCCAGGTGGTGGTGGAGAAGCGA
GCTGACGCCGGCTCCCACACGGAGGGCAGCCCATCGCAGCCCCGGGACCAAGAGCGCAGTGGCCCTGAGTCTGGGGCAGCCCGGGCCCCC
CGCAGCGAGGAAGACAAGAGACGGGCAGTGATCGAGAAGTGGGTGAACGGGGAGTACAGCGAGGAGCCGGCACCCACACCCGTGTTGGGG
CGGATTGCCCGCGAGGGCCTGGAGCTGCCTCCCGAGGGTGTCTACATGGTGCAGCCCCAGGGGTGCAGCGATGAGGAAGACCACGCGGAG
GAGCCCTCCAAGGACGGCGGTGCCCTGGAGGAGAAGGATTCGGACGGGGCAGCCTCCAAGGAGGACAGCGGCCCCAGCACCAGGCAGGCT
TCAGGAGAGGCCTCCTCGCTGCGGGACTACGCGGCCTCCACCATGACCGAGTTCCTCGGCATGTTTGGCTATGATGACCAGAACACGCGG
GACGAGCTGGCCAGGAAGATCAGCTTTGAGAAGCTGCACGCGGGCTCCACCCCGGAGGCAGCCACCTCCTCCATGCTGCCCACCTCCGAG
GATACCCTCAGCAAGCGGGCGCGGTTCTCTAAGTATGAGGAGTACATCCGCAAGCTCAAGGCTGGCGAGCAGCTCTCCTGGCCGGCCCCC
AGCACCAAGACCGAGGAGCGGGTGGGCAAGGAGGTGGTGGGCACCCTGCCCGGCCTGCGGCTGCCCAGCAGCACGGCCCACCTGGAGACC
AAGGCCACCATCCTGCCCCTGCCGTCGCACAGCAGTGTCCAGATGCAGAACCTGGTAGCCCGGGCCTCCAAGTACGACTTCTTCATCCAA
AAACTGAAGACCGGCGAGAATCTGCGGCCCCAGAACGGGAGCACCTACAAGAAGCCATCCAAGTACGACCTGGAGAATGTCAAGTACCTG
CACCTCTTCAAACCCGGGGAGGGCAGCCCCGACATGGGCGGGGCCATCGCCTTCAAGACAGGCAAGGTGGGGCGCCCTTCCAAGTACGAC
GTCCGGGGCATCCAGAAGCCAGGCCCCGCCAAGGTTCCGCCCACCCCCAGCCTGGCTCCCGCACCCCTCGCCAGCGTGCCCAGTGCCCCC
AGCGCCCCCGGGCCAGGGCCAGAGCCTCCTGCCTCCCTGTCCTTCAACACTCCCGAGTACCTGAAGTCAACCTTCTCCAAAACAGACTCC
ATCACCACGGGGACCGTCTCCACTGTCAAGAACGGACTGCCCACAGATAAACCAGCCGTCACTGAAGATGTAAACATTTACCAGAAATAT
ATTGCCAGGTTCTCGGGCAGCCAGCACTGTGGCCACATCCACTGTGCCTACCAGTACCGCGAGCACTACCACTGCCTTGACCCTGAGTGT
AACTACCAGAGGTTCACGAGTAAGCAGGACGTGATCCGCCACTACAACATGCACAAGAAGCGCGACAACTCCCTGCAGCACGGCTTCATG
CGTTTCAGCCCGCTGGACGACTGCAGCGTCTACTACCACGGCTGCCACCTCAATGGGAAGAGCACCCACTATCACTGCATGCAGGTGGGC
TGTAACAAGGTGTACACGAGCACGTCTGACGTGATGACCCACGAGAACTTCCACAAGAAGAATACCCAGCTCATTAACGACGGCTTCCAG
CGCTTCCGAGCCACCGAAGACTGTGGCACAGCCGACTGCCAGTTCTACGGACAGAAGACCACGCACTTCCACTGCAGGCGCCCCGGCTGC
ACATTCACTTTCAAGAACAAGTGTGACATCGAGAAGCACAAGAGCTACCACATCAAGGACGATGCCTACGCCAAGGACGGCTTCAAGAAG
TTCTACAAGTACGAGGAGTGCAAGTACGAGGGCTGCGTGTACAGCAAGGCTACCAACCACTTCCACTGCATCCGCGCCGGCTGCGGCTTC
ACCTTCACCTCCACCAGCCAGATGACCTCTCACAAGCGCAAGCATGAGCGCCGGCACATCCGCTCCTCGGGCGCGCTGGGGCTGCCGCCC
TCGCTGCTGGGCGCCAAGGACACGGAGCACGAGGAGTCCAGCAACGACGACCTTGTTGACTTCTCCGCCCTGAGCAGCAAGAACTCCAGC
CTGAGCGCCTCCCCTACCAGCCAGCAGTCCTCTGCGTCCCTGGCTGCCGCCACTGCCGCCACCGAGGCTGGGCCCAGTGCCACCAAACCT
CCCAACAGCAAGATCTCGGGGCTGCTGCCCCAGGGCCTGCCTGGCTCAATCCCCCTGGCCCTGGCCCTCTCCAACTCGGGCCTGCCCACC
CCCACGCCCTACTTCCCCATACTGGCTGGCCGTGGGAGCACCTCCCTGCCTGTGGGCACCCCCAGCCTCCTGGGTGCCGTGTCGTCTGGG
TCAGCAGCCTCAGCCACCCCTGACACACCCACGCTGGTCGCCTCGGGAGCTGGAGACTCAGCCCCCGTGGCTGCCGCCTCTGTCCCGGCA
CCACCCGCCTCCATCATGGAGAGGATCTCTGCAAGCAAGGGCCTCATCTCGCCCATGATGGCCAGGCTGGCTGCAGCTGCCCTCAAGCCC
TCTGCCACCTTTGACCCAGGAAGCGGGCAGCAGGTCACCCCAGCCAGGTTCCCCCCGGCCCAAGTGAAGCCGGAACCCGGTGAGAGCACC
GGCGCCCCAGGCCCCCACGAAGCCTCCCAGGACCGCAGTCTAGACCTGACTGTGAAGGAGCCCAGCAACGAATCAAATGGCCACGCAGTC
CCGGCAAATTCATCTCTTTTATCCTCGCTTATGAATAAGATGTCTCAGGGCAACCCTGGCCTGGGCAGCCTGCTGAACATCAAGGCGGAA
GCGGAGGGGAGCCCCGCTGCGGAGCCCTCGCCCTTCCTAGGCAAGGCCGTGAAGGCGCTGGTTCAGGAGAAGTTGGCAGAGCCCTGGAAG
GTGTACCTGCGCAGGTTTGGTACAAAGGACTTCTGTGACGGCCAGTGTGACTTCCTCCACAAGGCCCACTTCCACTGCGTGGTGGAGGAA
TGCGGCGCGCTCTTCAGCACCTTGGACGGGGCCATCAAGCACGCAAACTTCCACTTCCGGACAGAGGGAGGAGCAGCAAAAGGAAACACA
GAGGCTGCCTTTCCGGCCTCGGCCGCCGAGACCAAACCTCCCATGGCCCCCTCGTCCCCTCCGGTCCCTCCTGTCACCACGGCCACGGTG
TCCTCTCTGGAGGGGCCCGCTCCCAGCCCGGCCTCCGTGCCCTCCACCCCCACCCTGCTCGCCTGGAAGCAGCTGGCTTCCACCATACCC
CAGATGCCTCAGATCCCAGCGTCAGTGCCTCACCTGCCCGCCTCGCCCTTGGCAACGACTTCTCTAGAGAACGCCAAGCCCCAGGTCAAA

>In-frame_OBSCN_ENST00000422127_chr1_228412435_+_CASZ1_ENST00000377022_chr1_10725628_-_8193nt
ATGGATCAGCCACAGTTCAGCGGGGCGCCCCGCTTTCTCACCCGGCCCAAGGCCTTCGTGGTGTCGGTGGGCAAGGACGCCACCCTCAGC
TGCCAGATCGTGGGTAATCCCACGCCACAGGTGAGCTGGGAGAAGGACCAGCAGCCGGTGGCGGCCGGCGCGCGCTTCCGTCTGGCCCAG
GACGGCGACCTCTACCGCCTCACTATCCTGGACCTGGCGCTGGGCGACAGTGGGCAATACGTGTGCCGCGCGCGCAATGCCATAGGCGAG
GCCTTCGCTGCTGTGGGCCTGCAGGTGGACGCGGAGGCCGCGTGCGCCGAGCAGGCGCCGCACTTCCTGCTGCGGCCCACGTCCATCCGC
GTGCGCGAGGGCTCAGAGGCCACCTTCCGCTGCCGCGTGGGTGGCTCCCCGAGGCCGGCAGTGAGCTGGTCCAAGGACGGGCGGCGCCTG
GGTGAGCCCGACGGCCCCCGCGTGCGCGTGGAGGAGCTCGGCGAGGCAAGTGCGCTGCGCATTCGGGCGGCGCGGCCGCGCGACGGCGGC
ACTTACGAGGTCCGCGCCGAGAACCCGCTGGGCGCTGCCAGCGCCGCCGCGGCGCTAGTGGTGGACTCGGACGCCGCGGACACGGCCAGC
CGGCCCGGGACCTCCACGGCCGCGCTCCTGGCGCACCTGCAGCGGCGGCGCGAGGCTATGCGCGCCGAGGGCGCCCCCGCCTCACCGCCC
AGCACCGGCACGCGCACCTGCACGGTGACTGAAGGCAAGCACGCGCGCCTCAGCTGCTACGTGACCGGCGAGCCCAAGCCCGAGACGGTG
TGGAAGAAGGACGGCCAGCTGGTGACCGAGGGCCGGCGCCACGTGGTGTACGAGGACGCGCAGGAGAACTTCGTGCTCAAGATCCTCTTC
TGCAAGCAGTCGGACCGCGGCCTCTACACCTGCACGGCGTCCAACCTCGTGGGCCAGACCTACAGCTCTGTGCTGGTCGTAGTGCGCGAG
CCCGCGGTTCCCTTCAAAAAGCGGCTGCAAGATCTGGAGGTGCGGGAGAAGGAGTCGGCCACGTTCCTATGTGAGGTGCCCCAGCCGTCC
ACTGAGGCCGCGTGGTTCAAGGAGGAGACGCGGTTGTGGGCGAGCGCCAAGTACGGCATCGAGGAGGAGGGCACCGAGCGCCGCCTGACC
GTGCGCAATGTCTCGGCCGACGACGACGCGGTGTACATCTGCGAGACGCCAGAGGGCAGCCGCACGGTGGCGGAGCTCGCAGTCCAAGGA
AACCTCCTCCGAAAGCTCCCTCGGAAGACGGCGGTGCGCGTGGGCGACACGGCTATGTTTTGCGTGGAGCTGGCGGTCCCGGTGGGCCCC
GTCCACTGGCTGCGGAACCAGGAGGAAGTGGTGGCGGGGGGCCGCGTGGCCATCTCCGCGGAGGGCACGCGCCACACACTAACCATCTCC
CAGTGCTGCCTGGAGGATGTGGGCCAGGTGGCCTTTATGGCTGGCGACTGCCAGACGTCCACCCAGTTCTGCGTGTCGGCCCCCAGGAAG
CCTCCCCTGCAACCCCCTGTGGATCCTGTGGTAAAGGCCAGGATGGAGAGTTCCGTGATTCTCAGCTGGTCCCCACCACCCCATGGGGAA
CGCCCTGTCACTATCGACGGCTACCTGGTAGAGAAGAAGAAGCTTGGCACCTACACCTGGATCAGGTGCCACGAGGCTGAATGGGTGGCT
ACACCTGAGCTGACCGTGGCTGATGTGGCGGAGGAGGGGAACTTCCAGTTCCGAGTGTCCGCTCTCAACAGCTTTGGTCAGAGTCCCTAC
CTCGAGTTCCCGGGGACTGTCCACCTGGCCCCCAAGCTGGCCGTGAGGACACCGCTGAAGGCGGTGCAGGCGGTAGAGGGTGGCGAGGTC
ACTTTCTCCGTGGACCTCACGGTGGCCTCAGCGGGTGAGTGGTTCCTGGATGGGCAGGCCCTGAAGGCCAGCAGTGTGTATGAGATCCAC
TGTGATCGCACCCGGCACACGCTCACCATCCGGGAGGTGCCCGCCAGCCTGCACGGGGCGCAGCTGAAGTTCGTGGCCAACGGCATTGAG
AGCAGCATCCGGATGGAGGTCCGGGCGGCCCCAGGGCTGACTGCCAACAAGCCGCCAGCCGCAGCTGCCCGGGAGGTGCTGGCTCGGCTG
CACGAGGAGGCGCAGCTGCTGGCTGAGCTGTCAGATCAGGCTGCGGCTGTGACGTGGCTGAAGGATGGTCGCACACTGTCCCCAGGCCCC
AAGTATGAGGTGCAGGCATCGGCCGGGCGGCGGGTGCTCCTTGTGCGAGATGTGGCCCGGGACGATGCAGGCCTCTACGAGTGCGTCAGC
CGCGGGGGCCGCATCGCCTACCAGCTCTCCGTGCAAGGCCTCGCGCGCTTTCTGCACAAGGACATGGCGGGCAGCTGTGTGGATGCCGTG
GCTGGGGGCCCGGCGCAGTTTGAGTGTGAGACCTCCGAAGCCCACGTCCACGTGCACTGGTACAAGGATGGCATGGAGCTGGGCCACTCC
GGTGAGCGCTTCTTGCAGGAGGATGTGGGGACGCGGCACCGGCTGGTGGCAGCCACAGTCACCAGGCAGGATGAAGGCACCTACTCCTGC
CGCGTGGGCGAGGACTCTGTGGACTTCCGGCTCCGCGTCTCTGAGCCCAAGGTGGTGTTTGCTAAGGAGCAGCTGGCACGCAGGAAGCTG
CAGGCAGAGGCAGGAGCCAGTGCCACACTGAGCTGCGAGGTGGCCCAGGCCCAGACGGAGGTGACGTGGTACAAGGATGGGAAGAAGCTG
AGCTCCAGCTCGAAAGTGTGCATGGAGGCCACAGGCTGCACGCGCAGGCTGGTTGTGCAGCAGGCAGGCCAGGCGGATGCCGGGGAGTAT
AGCTGCGAGGCTGGGGGCCAGCGGCTCTCCTTCCATCTGGATGTCAAAGCTGAGGGCACCCGGTGCACGGACCCGCCTGCAGGCAAGCCC
GCCATGGCGCCCAAACGCAAGGGTGGCCTGAAGCTGAACGCCATCTGCGCCAAGCTGAGCCGCCAGGTGGTGGTGGAGAAGCGAGCTGAC
GCCGGCTCCCACACGGAGGGCAGCCCATCGCAGCCCCGGGACCAAGAGCGCAGTGGCCCTGAGTCTGGGGCAGCCCGGGCCCCCCGCAGC
GAGGAAGACAAGAGACGGGCAGTGATCGAGAAGTGGGTGAACGGGGAGTACAGCGAGGAGCCGGCACCCACACCCGTGTTGGGGCGGATT
GCCCGCGAGGGCCTGGAGCTGCCTCCCGAGGGTGTCTACATGGTGCAGCCCCAGGGGTGCAGCGATGAGGAAGACCACGCGGAGGAGCCC
TCCAAGGACGGCGGTGCCCTGGAGGAGAAGGATTCGGACGGGGCAGCCTCCAAGGAGGACAGCGGCCCCAGCACCAGGCAGGCTTCAGGA
GAGGCCTCCTCGCTGCGGGACTACGCGGCCTCCACCATGACCGAGTTCCTCGGCATGTTTGGCTATGATGACCAGAACACGCGGGACGAG
CTGGCCAGGAAGATCAGCTTTGAGAAGCTGCACGCGGGCTCCACCCCGGAGGCAGCCACCTCCTCCATGCTGCCCACCTCCGAGGATACC
CTCAGCAAGCGGGCGCGGTTCTCTAAGTATGAGGAGTACATCCGCAAGCTCAAGGCTGGCGAGCAGCTCTCCTGGCCGGCCCCCAGCACC
AAGACCGAGGAGCGGGTGGGCAAGGAGGTGGTGGGCACCCTGCCCGGCCTGCGGCTGCCCAGCAGCACGGCCCACCTGGAGACCAAGGCC
ACCATCCTGCCCCTGCCGTCGCACAGCAGTGTCCAGATGCAGAACCTGGTAGCCCGGGCCTCCAAGTACGACTTCTTCATCCAAAAACTG
AAGACCGGCGAGAATCTGCGGCCCCAGAACGGGAGCACCTACAAGAAGCCATCCAAGTACGACCTGGAGAATGTCAAGTACCTGCACCTC
TTCAAACCCGGGGAGGGCAGCCCCGACATGGGCGGGGCCATCGCCTTCAAGACAGGCAAGGTGGGGCGCCCTTCCAAGTACGACGTCCGG
GGCATCCAGAAGCCAGGCCCCGCCAAGGTTCCGCCCACCCCCAGCCTGGCTCCCGCACCCCTCGCCAGCGTGCCCAGTGCCCCCAGCGCC
CCCGGGCCAGGGCCAGAGCCTCCTGCCTCCCTGTCCTTCAACACTCCCGAGTACCTGAAGTCAACCTTCTCCAAAACAGACTCCATCACC
ACGGGGACCGTCTCCACTGTCAAGAACGGACTGCCCACAGATAAACCAGCCGTCACTGAAGATGTAAACATTTACCAGAAATATATTGCC
AGGTTCTCGGGCAGCCAGCACTGTGGCCACATCCACTGTGCCTACCAGTACCGCGAGCACTACCACTGCCTTGACCCTGAGTGTAACTAC
CAGAGGTTCACGAGTAAGCAGGACGTGATCCGCCACTACAACATGCACAAGAAGCGCGACAACTCCCTGCAGCACGGCTTCATGCGTTTC
AGCCCGCTGGACGACTGCAGCGTCTACTACCACGGCTGCCACCTCAATGGGAAGAGCACCCACTATCACTGCATGCAGGTGGGCTGTAAC
AAGGTGTACACGAGCACGTCTGACGTGATGACCCACGAGAACTTCCACAAGAAGAATACCCAGCTCATTAACGACGGCTTCCAGCGCTTC
CGAGCCACCGAAGACTGTGGCACAGCCGACTGCCAGTTCTACGGACAGAAGACCACGCACTTCCACTGCAGGCGCCCCGGCTGCACATTC
ACTTTCAAGAACAAGTGTGACATCGAGAAGCACAAGAGCTACCACATCAAGGACGATGCCTACGCCAAGGACGGCTTCAAGAAGTTCTAC
AAGTACGAGGAGTGCAAGTACGAGGGCTGCGTGTACAGCAAGGCTACCAACCACTTCCACTGCATCCGCGCCGGCTGCGGCTTCACCTTC
ACCTCCACCAGCCAGATGACCTCTCACAAGCGCAAGCATGAGCGCCGGCACATCCGCTCCTCGGGCGCGCTGGGGCTGCCGCCCTCGCTG
CTGGGCGCCAAGGACACGGAGCACGAGGAGTCCAGCAACGACGACCTTGTTGACTTCTCCGCCCTGAGCAGCAAGAACTCCAGCCTGAGC
GCCTCCCCTACCAGCCAGCAGTCCTCTGCGTCCCTGGCTGCCGCCACTGCCGCCACCGAGGCTGGGCCCAGTGCCACCAAACCTCCCAAC
AGCAAGATCTCGGGGCTGCTGCCCCAGGGCCTGCCTGGCTCAATCCCCCTGGCCCTGGCCCTCTCCAACTCGGGCCTGCCCACCCCCACG
CCCTACTTCCCCATACTGGCTGGCCGTGGGAGCACCTCCCTGCCTGTGGGCACCCCCAGCCTCCTGGGTGCCGTGTCGTCTGGGTCAGCA
GCCTCAGCCACCCCTGACACACCCACGCTGGTCGCCTCGGGAGCTGGAGACTCAGCCCCCGTGGCTGCCGCCTCTGTCCCGGCACCACCC
GCCTCCATCATGGAGAGGATCTCTGCAAGCAAGGGCCTCATCTCGCCCATGATGGCCAGGCTGGCTGCAGCTGCCCTCAAGCCCTCTGCC
ACCTTTGACCCAGGAAGCGGGCAGCAGGTCACCCCAGCCAGGTTCCCCCCGGCCCAAGTGAAGCCGGAACCCGGTGAGAGCACCGGCGCC
CCAGGCCCCCACGAAGCCTCCCAGGACCGCAGTCTAGACCTGACTGTGAAGGAGCCCAGCAACGAATCAAATGGCCACGCAGTCCCGGCA
AATTCATCTCTTTTATCCTCGCTTATGAATAAGATGTCTCAGGGCAACCCTGGCCTGGGCAGCCTGCTGAACATCAAGGCGGAAGCGGAG
GGGAGCCCCGCTGCGGAGCCCTCGCCCTTCCTAGGCAAGGCCGTGAAGGCGCTGGTTCAGGAGAAGTTGGCAGAGCCCTGGAAGGTGTAC
CTGCGCAGGTTTGGTACAAAGGACTTCTGTGACGGCCAGTGTGACTTCCTCCACAAGGCCCACTTCCACTGCGTGGTGGAGGAATGCGGC
GCGCTCTTCAGCACCTTGGACGGGGCCATCAAGCACGCAAACTTCCACTTCCGGACAGAGGGAGGAGCAGCAAAAGGAAACACAGAGGCT
GCCTTTCCGGCCTCGGCCGCCGAGACCAAACCTCCCATGGCCCCCTCGTCCCCTCCGGTCCCTCCTGTCACCACGGCCACGGTGTCCTCT
CTGGAGGGGCCCGCTCCCAGCCCGGCCTCCGTGCCCTCCACCCCCACCCTGCTCGCCTGGAAGCAGCTGGCTTCCACCATACCCCAGATG
CCTCAGATCCCAGCGTCAGTGCCTCACCTGCCCGCCTCGCCCTTGGCAACGACTTCTCTAGAGAACGCCAAGCCCCAGGTCAAACCCGGA
TTCCTCCAGTTCCAGGAGAACGATCCTTGCCTCGCCACGGACTGCAAGTACGCCAACAAGTTCCACTTCCACTGTCTCTTTGGGAACTGC
AAGTACGTCTGCAAAACGTCTGGCAAGGCCGAATCCCACTGCCTGGACCACATCAACCCCAACAACAACCTGGTGAACGTGCGAGACCAG
TTTGCATACTACTCTCTGCAGTGTCTCTGTCCCAACCAGCACTGCGAGTTCCGAATGCGTGGGCACTACCACTGCCTCCGCACCGGCTGC
TATTTTGTGACCAACATCACCACCAAGCTCCCCTGGCACATCAAGAAGCATGAGAAGGCGGAGCGGCGGGCAGCCAATGGCTTCAAATAC
TTCACCAAGCGCGAGGAGTGTGGCAGGCTAGGTTGCAAGTACAACCAGGTGAACAGCCACTTCCACTGCATCCGGGAGGGCTGCCAGTTC
TCCTTCCTCCTCAAGCACCAGATGACCTCCCACGCGCGGAAGCACATGCGGAGGATGCTGGGGAAGAACTTCGACCGCGTGCCCCCCTCC
CAGGGCCCCCCAGGCCTGATGGATGCTGAGACAGATGAGTGCATGGACTACACTGGCTGCAGCCCAGGCGCCATGTCCTCTGAGTCATCC
ACCATGGACCGGAGCTGCTCCAGCACCCCCGTGGGTAACGAGAGCACCGCGGCAGGGAACACCATCTCTATGCCGACAGCCTCGGGGGCC
AAAAAGCGCTTCTGGATCATCGAGGACATGTCGCCCTTCGGCAAGCGGCGGAAGACGGCGTCCTCCCGGAAGATGCTGGACGAGGGCATG
ATGCTGGAGGGCTTCCGGCGCTTCGACCTTTACGAGGACTGCAAGGACGCAGCTTGTCAGTTCTCGCTCAAGGTCACCCACTACCACTGC
ACGCGCGAGAACTGCGGCTACAAGTTCTGCGGGCGCACGCACATGTACAAGCACGCGCAGCACCACGACCGCGTGGACAACCTGGTGCTG
GACGACTTCAAGCGCTTCAAGGCCTCACTCAGCTGCCACTTCGCCGACTGCCCCTTCTCGGGCACCAGCACGCACTTCCACTGCCTGCGC
TGCCGCTTCCGCTGCACCGACAGCACCAAGGTCACGGCGCATCGCAAGCACCACGGCAAACAGGACGTGATCAGCGCCGCGGGCTTCTGC
CAGTTCAGCTCCAGCGCCGACTGCGCCGTGCCCGACTGCAAGTACAAGCTCAAGTGCTCGCACTTCCACTGCACCTTCCCGGGCTGCCGC
CACACGGTGGTGGGCATGTCGCAGATGGACTCGCACAAGCGCAAGCACGAGAAGCAGGAGCGCGGCGAGCCCGCGGCAGAGGGCCCCGCG
CCCGGGCCTCCCATCAGTCTGGACGGCTCCCTGTCGCTGGGCGCCGAGCCGGGCTCGCTGCTCTTCCTGCAGTCGGCGGCCGCCGGCCTG
GGCCTGGCGCTGGGCGACGCGGGCGACCCCGGCCCGCCCGACGCCGCCGCCCCCGGGCCGCGCGAGGGCGCCGCCGCCGCCGCCGCCGCA
GCTGGGGAGTCCTCGCAGGAGGACGAGGAGGAGGAGCTGGAGCTGCCGGAGGAGGAGGCCGAAGACGACGAGGACGAGGACGACGACGAG
GACGACGACGACGAGGACGACGACGAGGACGACGACGACGAGGACCTGCGCACCGACTCGGAGGAGTCGCTGCCCGAGGCGGCGGCGGAG
GCGGCGGGCGCGGGCGCGCGGACCCCGGCCTTGGCGGCGCTGGCGGCCCTGGGCGCCCCCGGCCCCGCGCCCACTGCAGCCTCCTCGCCC

>In-frame_OBSCN_ENST00000422127_chr1_228412435_+_CASZ1_ENST00000344008_chr1_10725628_-_6414nt
ATGGATCAGCCACAGTTCAGCGGGGCGCCCCGCTTTCTCACCCGGCCCAAGGCCTTCGTGGTGTCGGTGGGCAAGGACGCCACCCTCAGC
TGCCAGATCGTGGGTAATCCCACGCCACAGGTGAGCTGGGAGAAGGACCAGCAGCCGGTGGCGGCCGGCGCGCGCTTCCGTCTGGCCCAG
GACGGCGACCTCTACCGCCTCACTATCCTGGACCTGGCGCTGGGCGACAGTGGGCAATACGTGTGCCGCGCGCGCAATGCCATAGGCGAG
GCCTTCGCTGCTGTGGGCCTGCAGGTGGACGCGGAGGCCGCGTGCGCCGAGCAGGCGCCGCACTTCCTGCTGCGGCCCACGTCCATCCGC
GTGCGCGAGGGCTCAGAGGCCACCTTCCGCTGCCGCGTGGGTGGCTCCCCGAGGCCGGCAGTGAGCTGGTCCAAGGACGGGCGGCGCCTG
GGTGAGCCCGACGGCCCCCGCGTGCGCGTGGAGGAGCTCGGCGAGGCAAGTGCGCTGCGCATTCGGGCGGCGCGGCCGCGCGACGGCGGC
ACTTACGAGGTCCGCGCCGAGAACCCGCTGGGCGCTGCCAGCGCCGCCGCGGCGCTAGTGGTGGACTCGGACGCCGCGGACACGGCCAGC
CGGCCCGGGACCTCCACGGCCGCGCTCCTGGCGCACCTGCAGCGGCGGCGCGAGGCTATGCGCGCCGAGGGCGCCCCCGCCTCACCGCCC
AGCACCGGCACGCGCACCTGCACGGTGACTGAAGGCAAGCACGCGCGCCTCAGCTGCTACGTGACCGGCGAGCCCAAGCCCGAGACGGTG
TGGAAGAAGGACGGCCAGCTGGTGACCGAGGGCCGGCGCCACGTGGTGTACGAGGACGCGCAGGAGAACTTCGTGCTCAAGATCCTCTTC
TGCAAGCAGTCGGACCGCGGCCTCTACACCTGCACGGCGTCCAACCTCGTGGGCCAGACCTACAGCTCTGTGCTGGTCGTAGTGCGCGAG
CCCGCGGTTCCCTTCAAAAAGCGGCTGCAAGATCTGGAGGTGCGGGAGAAGGAGTCGGCCACGTTCCTATGTGAGGTGCCCCAGCCGTCC
ACTGAGGCCGCGTGGTTCAAGGAGGAGACGCGGTTGTGGGCGAGCGCCAAGTACGGCATCGAGGAGGAGGGCACCGAGCGCCGCCTGACC
GTGCGCAATGTCTCGGCCGACGACGACGCGGTGTACATCTGCGAGACGCCAGAGGGCAGCCGCACGGTGGCGGAGCTCGCAGTCCAAGGA
AACCTCCTCCGAAAGCTCCCTCGGAAGACGGCGGTGCGCGTGGGCGACACGGCTATGTTTTGCGTGGAGCTGGCGGTCCCGGTGGGCCCC
GTCCACTGGCTGCGGAACCAGGAGGAAGTGGTGGCGGGGGGCCGCGTGGCCATCTCCGCGGAGGGCACGCGCCACACACTAACCATCTCC
CAGTGCTGCCTGGAGGATGTGGGCCAGGTGGCCTTTATGGCTGGCGACTGCCAGACGTCCACCCAGTTCTGCGTGTCGGCCCCCAGGAAG
CCTCCCCTGCAACCCCCTGTGGATCCTGTGGTAAAGGCCAGGATGGAGAGTTCCGTGATTCTCAGCTGGTCCCCACCACCCCATGGGGAA
CGCCCTGTCACTATCGACGGCTACCTGGTAGAGAAGAAGAAGCTTGGCACCTACACCTGGATCAGGTGCCACGAGGCTGAATGGGTGGCT
ACACCTGAGCTGACCGTGGCTGATGTGGCGGAGGAGGGGAACTTCCAGTTCCGAGTGTCCGCTCTCAACAGCTTTGGTCAGAGTCCCTAC
CTCGAGTTCCCGGGGACTGTCCACCTGGCCCCCAAGCTGGCCGTGAGGACACCGCTGAAGGCGGTGCAGGCGGTAGAGGGTGGCGAGGTC
ACTTTCTCCGTGGACCTCACGGTGGCCTCAGCGGGTGAGTGGTTCCTGGATGGGCAGGCCCTGAAGGCCAGCAGTGTGTATGAGATCCAC
TGTGATCGCACCCGGCACACGCTCACCATCCGGGAGGTGCCCGCCAGCCTGCACGGGGCGCAGCTGAAGTTCGTGGCCAACGGCATTGAG
AGCAGCATCCGGATGGAGGTCCGGGCGGCCCCAGGGCTGACTGCCAACAAGCCGCCAGCCGCAGCTGCCCGGGAGGTGCTGGCTCGGCTG
CACGAGGAGGCGCAGCTGCTGGCTGAGCTGTCAGATCAGGCTGCGGCTGTGACGTGGCTGAAGGATGGTCGCACACTGTCCCCAGGCCCC
AAGTATGAGGTGCAGGCATCGGCCGGGCGGCGGGTGCTCCTTGTGCGAGATGTGGCCCGGGACGATGCAGGCCTCTACGAGTGCGTCAGC
CGCGGGGGCCGCATCGCCTACCAGCTCTCCGTGCAAGGCCTCGCGCGCTTTCTGCACAAGGACATGGCGGGCAGCTGTGTGGATGCCGTG
GCTGGGGGCCCGGCGCAGTTTGAGTGTGAGACCTCCGAAGCCCACGTCCACGTGCACTGGTACAAGGATGGCATGGAGCTGGGCCACTCC
GGTGAGCGCTTCTTGCAGGAGGATGTGGGGACGCGGCACCGGCTGGTGGCAGCCACAGTCACCAGGCAGGATGAAGGCACCTACTCCTGC
CGCGTGGGCGAGGACTCTGTGGACTTCCGGCTCCGCGTCTCTGAGCCCAAGGTGGTGTTTGCTAAGGAGCAGCTGGCACGCAGGAAGCTG
CAGGCAGAGGCAGGAGCCAGTGCCACACTGAGCTGCGAGGTGGCCCAGGCCCAGACGGAGGTGACGTGGTACAAGGATGGGAAGAAGCTG
AGCTCCAGCTCGAAAGTGTGCATGGAGGCCACAGGCTGCACGCGCAGGCTGGTTGTGCAGCAGGCAGGCCAGGCGGATGCCGGGGAGTAT
AGCTGCGAGGCTGGGGGCCAGCGGCTCTCCTTCCATCTGGATGTCAAAGCTGAGGGCACCCGGTGCACGGACCCGCCTGCAGGCAAGCCC
GCCATGGCGCCCAAACGCAAGGGTGGCCTGAAGCTGAACGCCATCTGCGCCAAGCTGAGCCGCCAGGTGGTGGTGGAGAAGCGAGCTGAC
GCCGGCTCCCACACGGAGGGCAGCCCATCGCAGCCCCGGGACCAAGAGCGCAGTGGCCCTGAGTCTGGGGCAGCCCGGGCCCCCCGCAGC
GAGGAAGACAAGAGACGGGCAGTGATCGAGAAGTGGGTGAACGGGGAGTACAGCGAGGAGCCGGCACCCACACCCGTGTTGGGGCGGATT
GCCCGCGAGGGCCTGGAGCTGCCTCCCGAGGGTGTCTACATGGTGCAGCCCCAGGGGTGCAGCGATGAGGAAGACCACGCGGAGGAGCCC
TCCAAGGACGGCGGTGCCCTGGAGGAGAAGGATTCGGACGGGGCAGCCTCCAAGGAGGACAGCGGCCCCAGCACCAGGCAGGCTTCAGGA
GAGGCCTCCTCGCTGCGGGACTACGCGGCCTCCACCATGACCGAGTTCCTCGGCATGTTTGGCTATGATGACCAGAACACGCGGGACGAG
CTGGCCAGGAAGATCAGCTTTGAGAAGCTGCACGCGGGCTCCACCCCGGAGGCAGCCACCTCCTCCATGCTGCCCACCTCCGAGGATACC
CTCAGCAAGCGGGCGCGGTTCTCTAAGTATGAGGAGTACATCCGCAAGCTCAAGGCTGGCGAGCAGCTCTCCTGGCCGGCCCCCAGCACC
AAGACCGAGGAGCGGGTGGGCAAGGAGGTGGTGGGCACCCTGCCCGGCCTGCGGCTGCCCAGCAGCACGGCCCACCTGGAGACCAAGGCC
ACCATCCTGCCCCTGCCGTCGCACAGCAGTGTCCAGATGCAGAACCTGGTAGCCCGGGCCTCCAAGTACGACTTCTTCATCCAAAAACTG
AAGACCGGCGAGAATCTGCGGCCCCAGAACGGGAGCACCTACAAGAAGCCATCCAAGTACGACCTGGAGAATGTCAAGTACCTGCACCTC
TTCAAACCCGGGGAGGGCAGCCCCGACATGGGCGGGGCCATCGCCTTCAAGACAGGCAAGGTGGGGCGCCCTTCCAAGTACGACGTCCGG
GGCATCCAGAAGCCAGGCCCCGCCAAGGTTCCGCCCACCCCCAGCCTGGCTCCCGCACCCCTCGCCAGCGTGCCCAGTGCCCCCAGCGCC
CCCGGGCCAGGGCCAGAGCCTCCTGCCTCCCTGTCCTTCAACACTCCCGAGTACCTGAAGTCAACCTTCTCCAAAACAGACTCCATCACC
ACGGGGACCGTCTCCACTGTCAAGAACGGACTGCCCACAGATAAACCAGCCGTCACTGAAGATGTAAACATTTACCAGAAATATATTGCC
AGGTTCTCGGGCAGCCAGCACTGTGGCCACATCCACTGTGCCTACCAGTACCGCGAGCACTACCACTGCCTTGACCCTGAGTGTAACTAC
CAGAGGTTCACGAGTAAGCAGGACGTGATCCGCCACTACAACATGCACAAGAAGCGCGACAACTCCCTGCAGCACGGCTTCATGCGTTTC
AGCCCGCTGGACGACTGCAGCGTCTACTACCACGGCTGCCACCTCAATGGGAAGAGCACCCACTATCACTGCATGCAGGTGGGCTGTAAC
AAGGTGTACACGAGCACGTCTGACGTGATGACCCACGAGAACTTCCACAAGAAGAATACCCAGCTCATTAACGACGGCTTCCAGCGCTTC
CGAGCCACCGAAGACTGTGGCACAGCCGACTGCCAGTTCTACGGACAGAAGACCACGCACTTCCACTGCAGGCGCCCCGGCTGCACATTC
ACTTTCAAGAACAAGTGTGACATCGAGAAGCACAAGAGCTACCACATCAAGGACGATGCCTACGCCAAGGACGGCTTCAAGAAGTTCTAC
AAGTACGAGGAGTGCAAGTACGAGGGCTGCGTGTACAGCAAGGCTACCAACCACTTCCACTGCATCCGCGCCGGCTGCGGCTTCACCTTC
ACCTCCACCAGCCAGATGACCTCTCACAAGCGCAAGCATGAGCGCCGGCACATCCGCTCCTCGGGCGCGCTGGGGCTGCCGCCCTCGCTG
CTGGGCGCCAAGGACACGGAGCACGAGGAGTCCAGCAACGACGACCTTGTTGACTTCTCCGCCCTGAGCAGCAAGAACTCCAGCCTGAGC
GCCTCCCCTACCAGCCAGCAGTCCTCTGCGTCCCTGGCTGCCGCCACTGCCGCCACCGAGGCTGGGCCCAGTGCCACCAAACCTCCCAAC
AGCAAGATCTCGGGGCTGCTGCCCCAGGGCCTGCCTGGCTCAATCCCCCTGGCCCTGGCCCTCTCCAACTCGGGCCTGCCCACCCCCACG
CCCTACTTCCCCATACTGGCTGGCCGTGGGAGCACCTCCCTGCCTGTGGGCACCCCCAGCCTCCTGGGTGCCGTGTCGTCTGGGTCAGCA
GCCTCAGCCACCCCTGACACACCCACGCTGGTCGCCTCGGGAGCTGGAGACTCAGCCCCCGTGGCTGCCGCCTCTGTCCCGGCACCACCC
GCCTCCATCATGGAGAGGATCTCTGCAAGCAAGGGCCTCATCTCGCCCATGATGGCCAGGCTGGCTGCAGCTGCCCTCAAGCCCTCTGCC
ACCTTTGACCCAGGAAGCGGGCAGCAGGTCACCCCAGCCAGGTTCCCCCCGGCCCAAGTGAAGCCGGAACCCGGTGAGAGCACCGGCGCC
CCAGGCCCCCACGAAGCCTCCCAGGACCGCAGTCTAGACCTGACTGTGAAGGAGCCCAGCAACGAATCAAATGGCCACGCAGTCCCGGCA
AATTCATCTCTTTTATCCTCGCTTATGAATAAGATGTCTCAGGGCAACCCTGGCCTGGGCAGCCTGCTGAACATCAAGGCGGAAGCGGAG
GGGAGCCCCGCTGCGGAGCCCTCGCCCTTCCTAGGCAAGGCCGTGAAGGCGCTGGTTCAGGAGAAGTTGGCAGAGCCCTGGAAGGTGTAC
CTGCGCAGGTTTGGTACAAAGGACTTCTGTGACGGCCAGTGTGACTTCCTCCACAAGGCCCACTTCCACTGCGTGGTGGAGGAATGCGGC
GCGCTCTTCAGCACCTTGGACGGGGCCATCAAGCACGCAAACTTCCACTTCCGGACAGAGGGAGGAGCAGCAAAAGGAAACACAGAGGCT
GCCTTTCCGGCCTCGGCCGCCGAGACCAAACCTCCCATGGCCCCCTCGTCCCCTCCGGTCCCTCCTGTCACCACGGCCACGGTGTCCTCT
CTGGAGGGGCCCGCTCCCAGCCCGGCCTCCGTGCCCTCCACCCCCACCCTGCTCGCCTGGAAGCAGCTGGCTTCCACCATACCCCAGATG
CCTCAGATCCCAGCGTCAGTGCCTCACCTGCCCGCCTCGCCCTTGGCAACGACTTCTCTAGAGAACGCCAAGCCCCAGGTCAAACCCGGA


* Fusion transcript sequences (Full-length transcript).
>In-frame_OBSCN_ENST00000284548_chr1_228412435_+_CASZ1_ENST00000377022_chr1_10725628_-_10605nt
TGCCTCCCAGCCTGTGCCCCCAGCCTGCGTGCTGCCCAGAGCCCCCATAGAGAGAGGTCCCCGCCGCCACCCTCATGGATCAGCCACAGT
TCAGCGGGGCGCCCCGCTTTCTCACCCGGCCCAAGGCCTTCGTGGTGTCGGTGGGCAAGGACGCCACCCTCAGCTGCCAGATCGTGGGTA
ATCCCACGCCACAGGTGAGCTGGGAGAAGGACCAGCAGCCGGTGGCGGCCGGCGCGCGCTTCCGTCTGGCCCAGGACGGCGACCTCTACC
GCCTCACTATCCTGGACCTGGCGCTGGGCGACAGTGGGCAATACGTGTGCCGCGCGCGCAATGCCATAGGCGAGGCCTTCGCTGCTGTGG
GCCTGCAGGTGGACGCGGAGGCCGCGTGCGCCGAGCAGGCGCCGCACTTCCTGCTGCGGCCCACGTCCATCCGCGTGCGCGAGGGCTCAG
AGGCCACCTTCCGCTGCCGCGTGGGTGGCTCCCCGAGGCCGGCAGTGAGCTGGTCCAAGGACGGGCGGCGCCTGGGTGAGCCCGACGGCC
CCCGCGTGCGCGTGGAGGAGCTCGGCGAGGCAAGTGCGCTGCGCATTCGGGCGGCGCGGCCGCGCGACGGCGGCACTTACGAGGTCCGCG
CCGAGAACCCGCTGGGCGCTGCCAGCGCCGCCGCGGCGCTAGTGGTGGACTCGGACGCCGCGGACACGGCCAGCCGGCCCGGGACCTCCA
CGGCCGCGCTCCTGGCGCACCTGCAGCGGCGGCGCGAGGCTATGCGCGCCGAGGGCGCCCCCGCCTCACCGCCCAGCACCGGCACGCGCA
CCTGCACGGTGACTGAAGGCAAGCACGCGCGCCTCAGCTGCTACGTGACCGGCGAGCCCAAGCCCGAGACGGTGTGGAAGAAGGACGGCC
AGCTGGTGACCGAGGGCCGGCGCCACGTGGTGTACGAGGACGCGCAGGAGAACTTCGTGCTCAAGATCCTCTTCTGCAAGCAGTCGGACC
GCGGCCTCTACACCTGCACGGCGTCCAACCTCGTGGGCCAGACCTACAGCTCTGTGCTGGTCGTAGTGCGCGAGCCCGCGGTTCCCTTCA
AAAAGCGGCTGCAAGATCTGGAGGTGCGGGAGAAGGAGTCGGCCACGTTCCTATGTGAGGTGCCCCAGCCGTCCACTGAGGCCGCGTGGT
TCAAGGAGGAGACGCGGTTGTGGGCGAGCGCCAAGTACGGCATCGAGGAGGAGGGCACCGAGCGCCGCCTGACCGTGCGCAATGTCTCGG
CCGACGACGACGCGGTGTACATCTGCGAGACGCCAGAGGGCAGCCGCACGGTGGCGGAGCTCGCAGTCCAAGGAAACCTCCTCCGAAAGC
TCCCTCGGAAGACGGCGGTGCGCGTGGGCGACACGGCTATGTTTTGCGTGGAGCTGGCGGTCCCGGTGGGCCCCGTCCACTGGCTGCGGA
ACCAGGAGGAAGTGGTGGCGGGGGGCCGCGTGGCCATCTCCGCGGAGGGCACGCGCCACACACTAACCATCTCCCAGTGCTGCCTGGAGG
ATGTGGGCCAGGTGGCCTTTATGGCTGGCGACTGCCAGACGTCCACCCAGTTCTGCGTGTCGGCCCCCAGGAAGCCTCCCCTGCAACCCC
CTGTGGATCCTGTGGTAAAGGCCAGGATGGAGAGTTCCGTGATTCTCAGCTGGTCCCCACCACCCCATGGGGAACGCCCTGTCACTATCG
ACGGCTACCTGGTAGAGAAGAAGAAGCTTGGCACCTACACCTGGATCAGGTGCCACGAGGCTGAATGGGTGGCTACACCTGAGCTGACCG
TGGCTGATGTGGCGGAGGAGGGGAACTTCCAGTTCCGAGTGTCCGCTCTCAACAGCTTTGGTCAGAGTCCCTACCTCGAGTTCCCGGGGA
CTGTCCACCTGGCCCCCAAGCTGGCCGTGAGGACACCGCTGAAGGCGGTGCAGGCGGTAGAGGGTGGCGAGGTCACTTTCTCCGTGGACC
TCACGGTGGCCTCAGCGGGTGAGTGGTTCCTGGATGGGCAGGCCCTGAAGGCCAGCAGTGTGTATGAGATCCACTGTGATCGCACCCGGC
ACACGCTCACCATCCGGGAGGTGCCCGCCAGCCTGCACGGGGCGCAGCTGAAGTTCGTGGCCAACGGCATTGAGAGCAGCATCCGGATGG
AGGTCCGGGCGGCCCCAGGGCTGACTGCCAACAAGCCGCCAGCCGCAGCTGCCCGGGAGGTGCTGGCTCGGCTGCACGAGGAGGCGCAGC
TGCTGGCTGAGCTGTCAGATCAGGCTGCGGCTGTGACGTGGCTGAAGGATGGTCGCACACTGTCCCCAGGCCCCAAGTATGAGGTGCAGG
CATCGGCCGGGCGGCGGGTGCTCCTTGTGCGAGATGTGGCCCGGGACGATGCAGGCCTCTACGAGTGCGTCAGCCGCGGGGGCCGCATCG
CCTACCAGCTCTCCGTGCAAGGCCTCGCGCGCTTTCTGCACAAGGACATGGCGGGCAGCTGTGTGGATGCCGTGGCTGGGGGCCCGGCGC
AGTTTGAGTGTGAGACCTCCGAAGCCCACGTCCACGTGCACTGGTACAAGGATGGCATGGAGCTGGGCCACTCCGGTGAGCGCTTCTTGC
AGGAGGATGTGGGGACGCGGCACCGGCTGGTGGCAGCCACAGTCACCAGGCAGGATGAAGGCACCTACTCCTGCCGCGTGGGCGAGGACT
CTGTGGACTTCCGGCTCCGCGTCTCTGAGCCCAAGGTGGTGTTTGCTAAGGAGCAGCTGGCACGCAGGAAGCTGCAGGCAGAGGCAGGAG
CCAGTGCCACACTGAGCTGCGAGGTGGCCCAGGCCCAGACGGAGGTGACGTGGTACAAGGATGGGAAGAAGCTGAGCTCCAGCTCGAAAG
TGTGCATGGAGGCCACAGGCTGCACGCGCAGGCTGGTTGTGCAGCAGGCAGGCCAGGCGGATGCCGGGGAGTATAGCTGCGAGGCTGGGG
GCCAGCGGCTCTCCTTCCATCTGGATGTCAAAGCTGAGGGCACCCGGTGCACGGACCCGCCTGCAGGCAAGCCCGCCATGGCGCCCAAAC
GCAAGGGTGGCCTGAAGCTGAACGCCATCTGCGCCAAGCTGAGCCGCCAGGTGGTGGTGGAGAAGCGAGCTGACGCCGGCTCCCACACGG
AGGGCAGCCCATCGCAGCCCCGGGACCAAGAGCGCAGTGGCCCTGAGTCTGGGGCAGCCCGGGCCCCCCGCAGCGAGGAAGACAAGAGAC
GGGCAGTGATCGAGAAGTGGGTGAACGGGGAGTACAGCGAGGAGCCGGCACCCACACCCGTGTTGGGGCGGATTGCCCGCGAGGGCCTGG
AGCTGCCTCCCGAGGGTGTCTACATGGTGCAGCCCCAGGGGTGCAGCGATGAGGAAGACCACGCGGAGGAGCCCTCCAAGGACGGCGGTG
CCCTGGAGGAGAAGGATTCGGACGGGGCAGCCTCCAAGGAGGACAGCGGCCCCAGCACCAGGCAGGCTTCAGGAGAGGCCTCCTCGCTGC
GGGACTACGCGGCCTCCACCATGACCGAGTTCCTCGGCATGTTTGGCTATGATGACCAGAACACGCGGGACGAGCTGGCCAGGAAGATCA
GCTTTGAGAAGCTGCACGCGGGCTCCACCCCGGAGGCAGCCACCTCCTCCATGCTGCCCACCTCCGAGGATACCCTCAGCAAGCGGGCGC
GGTTCTCTAAGTATGAGGAGTACATCCGCAAGCTCAAGGCTGGCGAGCAGCTCTCCTGGCCGGCCCCCAGCACCAAGACCGAGGAGCGGG
TGGGCAAGGAGGTGGTGGGCACCCTGCCCGGCCTGCGGCTGCCCAGCAGCACGGCCCACCTGGAGACCAAGGCCACCATCCTGCCCCTGC
CGTCGCACAGCAGTGTCCAGATGCAGAACCTGGTAGCCCGGGCCTCCAAGTACGACTTCTTCATCCAAAAACTGAAGACCGGCGAGAATC
TGCGGCCCCAGAACGGGAGCACCTACAAGAAGCCATCCAAGTACGACCTGGAGAATGTCAAGTACCTGCACCTCTTCAAACCCGGGGAGG
GCAGCCCCGACATGGGCGGGGCCATCGCCTTCAAGACAGGCAAGGTGGGGCGCCCTTCCAAGTACGACGTCCGGGGCATCCAGAAGCCAG
GCCCCGCCAAGGTTCCGCCCACCCCCAGCCTGGCTCCCGCACCCCTCGCCAGCGTGCCCAGTGCCCCCAGCGCCCCCGGGCCAGGGCCAG
AGCCTCCTGCCTCCCTGTCCTTCAACACTCCCGAGTACCTGAAGTCAACCTTCTCCAAAACAGACTCCATCACCACGGGGACCGTCTCCA
CTGTCAAGAACGGACTGCCCACAGATAAACCAGCCGTCACTGAAGATGTAAACATTTACCAGAAATATATTGCCAGGTTCTCGGGCAGCC
AGCACTGTGGCCACATCCACTGTGCCTACCAGTACCGCGAGCACTACCACTGCCTTGACCCTGAGTGTAACTACCAGAGGTTCACGAGTA
AGCAGGACGTGATCCGCCACTACAACATGCACAAGAAGCGCGACAACTCCCTGCAGCACGGCTTCATGCGTTTCAGCCCGCTGGACGACT
GCAGCGTCTACTACCACGGCTGCCACCTCAATGGGAAGAGCACCCACTATCACTGCATGCAGGTGGGCTGTAACAAGGTGTACACGAGCA
CGTCTGACGTGATGACCCACGAGAACTTCCACAAGAAGAATACCCAGCTCATTAACGACGGCTTCCAGCGCTTCCGAGCCACCGAAGACT
GTGGCACAGCCGACTGCCAGTTCTACGGACAGAAGACCACGCACTTCCACTGCAGGCGCCCCGGCTGCACATTCACTTTCAAGAACAAGT
GTGACATCGAGAAGCACAAGAGCTACCACATCAAGGACGATGCCTACGCCAAGGACGGCTTCAAGAAGTTCTACAAGTACGAGGAGTGCA
AGTACGAGGGCTGCGTGTACAGCAAGGCTACCAACCACTTCCACTGCATCCGCGCCGGCTGCGGCTTCACCTTCACCTCCACCAGCCAGA
TGACCTCTCACAAGCGCAAGCATGAGCGCCGGCACATCCGCTCCTCGGGCGCGCTGGGGCTGCCGCCCTCGCTGCTGGGCGCCAAGGACA
CGGAGCACGAGGAGTCCAGCAACGACGACCTTGTTGACTTCTCCGCCCTGAGCAGCAAGAACTCCAGCCTGAGCGCCTCCCCTACCAGCC
AGCAGTCCTCTGCGTCCCTGGCTGCCGCCACTGCCGCCACCGAGGCTGGGCCCAGTGCCACCAAACCTCCCAACAGCAAGATCTCGGGGC
TGCTGCCCCAGGGCCTGCCTGGCTCAATCCCCCTGGCCCTGGCCCTCTCCAACTCGGGCCTGCCCACCCCCACGCCCTACTTCCCCATAC
TGGCTGGCCGTGGGAGCACCTCCCTGCCTGTGGGCACCCCCAGCCTCCTGGGTGCCGTGTCGTCTGGGTCAGCAGCCTCAGCCACCCCTG
ACACACCCACGCTGGTCGCCTCGGGAGCTGGAGACTCAGCCCCCGTGGCTGCCGCCTCTGTCCCGGCACCACCCGCCTCCATCATGGAGA
GGATCTCTGCAAGCAAGGGCCTCATCTCGCCCATGATGGCCAGGCTGGCTGCAGCTGCCCTCAAGCCCTCTGCCACCTTTGACCCAGGAA
GCGGGCAGCAGGTCACCCCAGCCAGGTTCCCCCCGGCCCAAGTGAAGCCGGAACCCGGTGAGAGCACCGGCGCCCCAGGCCCCCACGAAG
CCTCCCAGGACCGCAGTCTAGACCTGACTGTGAAGGAGCCCAGCAACGAATCAAATGGCCACGCAGTCCCGGCAAATTCATCTCTTTTAT
CCTCGCTTATGAATAAGATGTCTCAGGGCAACCCTGGCCTGGGCAGCCTGCTGAACATCAAGGCGGAAGCGGAGGGGAGCCCCGCTGCGG
AGCCCTCGCCCTTCCTAGGCAAGGCCGTGAAGGCGCTGGTTCAGGAGAAGTTGGCAGAGCCCTGGAAGGTGTACCTGCGCAGGTTTGGTA
CAAAGGACTTCTGTGACGGCCAGTGTGACTTCCTCCACAAGGCCCACTTCCACTGCGTGGTGGAGGAATGCGGCGCGCTCTTCAGCACCT
TGGACGGGGCCATCAAGCACGCAAACTTCCACTTCCGGACAGAGGGAGGAGCAGCAAAAGGAAACACAGAGGCTGCCTTTCCGGCCTCGG
CCGCCGAGACCAAACCTCCCATGGCCCCCTCGTCCCCTCCGGTCCCTCCTGTCACCACGGCCACGGTGTCCTCTCTGGAGGGGCCCGCTC
CCAGCCCGGCCTCCGTGCCCTCCACCCCCACCCTGCTCGCCTGGAAGCAGCTGGCTTCCACCATACCCCAGATGCCTCAGATCCCAGCGT
CAGTGCCTCACCTGCCCGCCTCGCCCTTGGCAACGACTTCTCTAGAGAACGCCAAGCCCCAGGTCAAACCCGGATTCCTCCAGTTCCAGG
AGAACGATCCTTGCCTCGCCACGGACTGCAAGTACGCCAACAAGTTCCACTTCCACTGTCTCTTTGGGAACTGCAAGTACGTCTGCAAAA
CGTCTGGCAAGGCCGAATCCCACTGCCTGGACCACATCAACCCCAACAACAACCTGGTGAACGTGCGAGACCAGTTTGCATACTACTCTC
TGCAGTGTCTCTGTCCCAACCAGCACTGCGAGTTCCGAATGCGTGGGCACTACCACTGCCTCCGCACCGGCTGCTATTTTGTGACCAACA
TCACCACCAAGCTCCCCTGGCACATCAAGAAGCATGAGAAGGCGGAGCGGCGGGCAGCCAATGGCTTCAAATACTTCACCAAGCGCGAGG
AGTGTGGCAGGCTAGGTTGCAAGTACAACCAGGTGAACAGCCACTTCCACTGCATCCGGGAGGGCTGCCAGTTCTCCTTCCTCCTCAAGC
ACCAGATGACCTCCCACGCGCGGAAGCACATGCGGAGGATGCTGGGGAAGAACTTCGACCGCGTGCCCCCCTCCCAGGGCCCCCCAGGCC
TGATGGATGCTGAGACAGATGAGTGCATGGACTACACTGGCTGCAGCCCAGGCGCCATGTCCTCTGAGTCATCCACCATGGACCGGAGCT
GCTCCAGCACCCCCGTGGGTAACGAGAGCACCGCGGCAGGGAACACCATCTCTATGCCGACAGCCTCGGGGGCCAAAAAGCGCTTCTGGA
TCATCGAGGACATGTCGCCCTTCGGCAAGCGGCGGAAGACGGCGTCCTCCCGGAAGATGCTGGACGAGGGCATGATGCTGGAGGGCTTCC
GGCGCTTCGACCTTTACGAGGACTGCAAGGACGCAGCTTGTCAGTTCTCGCTCAAGGTCACCCACTACCACTGCACGCGCGAGAACTGCG
GCTACAAGTTCTGCGGGCGCACGCACATGTACAAGCACGCGCAGCACCACGACCGCGTGGACAACCTGGTGCTGGACGACTTCAAGCGCT
TCAAGGCCTCACTCAGCTGCCACTTCGCCGACTGCCCCTTCTCGGGCACCAGCACGCACTTCCACTGCCTGCGCTGCCGCTTCCGCTGCA
CCGACAGCACCAAGGTCACGGCGCATCGCAAGCACCACGGCAAACAGGACGTGATCAGCGCCGCGGGCTTCTGCCAGTTCAGCTCCAGCG
CCGACTGCGCCGTGCCCGACTGCAAGTACAAGCTCAAGTGCTCGCACTTCCACTGCACCTTCCCGGGCTGCCGCCACACGGTGGTGGGCA
TGTCGCAGATGGACTCGCACAAGCGCAAGCACGAGAAGCAGGAGCGCGGCGAGCCCGCGGCAGAGGGCCCCGCGCCCGGGCCTCCCATCA
GTCTGGACGGCTCCCTGTCGCTGGGCGCCGAGCCGGGCTCGCTGCTCTTCCTGCAGTCGGCGGCCGCCGGCCTGGGCCTGGCGCTGGGCG
ACGCGGGCGACCCCGGCCCGCCCGACGCCGCCGCCCCCGGGCCGCGCGAGGGCGCCGCCGCCGCCGCCGCCGCAGCTGGGGAGTCCTCGC
AGGAGGACGAGGAGGAGGAGCTGGAGCTGCCGGAGGAGGAGGCCGAAGACGACGAGGACGAGGACGACGACGAGGACGACGACGACGAGG
ACGACGACGAGGACGACGACGACGAGGACCTGCGCACCGACTCGGAGGAGTCGCTGCCCGAGGCGGCGGCGGAGGCGGCGGGCGCGGGCG
CGCGGACCCCGGCCTTGGCGGCGCTGGCGGCCCTGGGCGCCCCCGGCCCCGCGCCCACTGCAGCCTCCTCGCCCTAGCGGCGCCCGCGGG
TGGCCCTGGCGGCGGCCTCGGCCTCGGCCTCGGGAGCGGCGCCGCCCCGCGCGAAGCGGCCCCTGGGCAGAGCCCCGCGCCCCGCCGGTG
CTTCCGGACCCCGAGTCCGTCTCAGGACAGAGGCGGGGACCCCTCTGGTGCTCCGCGGCCGAGGACACAGGCGGCGGCGGTGGCCCTGCT
CTAGGGAGGCCGGGTCTCTTCAGGGAAACAGAAGGTGCTCTTGTCCCGGGGTAGGGAACCTAGGAGCAGGGGTCCCGGGCGAATGCGGCG
CAGCTCCCGGCCGCTGCCCCGGCGCCCCTCCCCGCGGCCGATTCGGCCCCGCGACCATTGCTCAGGACTGGGACGGGCGCTGGGGGCCAC
CGGGACCCCCACCGCGCGCCACCAGGGCGGGGTGGCTCCTGGAGCCGCTGGCGGGGCCTCCCTCATGCAGCTAGGATCCTCCCCCCTGCC
CAGGGGGAGACGGGCAGAAGGCAGTCAGCACGGGTGACACTACAGGGACCGTGGAGGAAGCCTCACGGGAGTAGCAGCCGCGGAGCTCCA
GCTCAGCCCCACCCCAGGGCCCGGCTGCTCCCCCAGGCCTGGGTCGGGTCTGTTTGGCGACTCCCTGGCCCCAGCCTCCGCCCCAGGGAA
ACCGAGGCTGCGTCCAAAACCCAGAGTAGCCCGCTGGGGGCCGGGGCGGGGTCTCGGCCACCCTGGTGGTGCAAACAGGAAGGATGCGCC
TGGTTTTGGCTTTAATGTTCAAAATGGAAAAAAATACAAGAAAGTTGTACAGTATTTTTCCTGTAAAGGTTATTATTCTACATAGAACAA
AAAGGAAGAAAGCAGGCGTGGTGAGAGTGCAGACCCGCCTGGGCCCGGCCTGAGGTTGGAGGCTCAGTCCCGTTTATCCTGTGGGATTTG
GTCCAGGGTTTTTGTAGAGGCCTTAACTGTTTGAGGCTGTCTGTCTTCACAATAGCACTGATGGGAGCTGCGTGATTCCAACTCTTAACT
TGAATTTTGTAGAGACAAGAAAAAAGGACTATTACTGTTGATCCAAGTTTGTAGTTAATTTAACATTTGAGTTCTCTCTTGGTGATGCGT
GTGGCTTTATAGGGCTTTTTTTTTTTTCCAGTTTGTTTTATTACTTTGTTTGGGATGCTTCTTCGCTGGTGCAGTCTACCCAGATTGGGT
TCCCTTTGCAAAACATCCCCCTTCCTGGAGATGATGATGCCATCGAAGCCCGGGCCAGGGCCTGACCTGGCAGGCACACACCTGGCCAGT
GGCTCTGAGGTCCCCGGGGACCGAGTCCCCTGCGAGGGCAGGCTGCCCGAGGCCACACCTGCCCACCTTCCCTACTCCAGGCCACCAGCT
GGTGTCAGATTGGGCCACCGGGAGAGAACAGGCCTAGGAGGGAATGGAAGGCTGGCGGGGAGGCTGTCATCCAGAAGCCTCCTCCCCAGA
GGTCTCCAGGAGGAACCTGGCTCAACTGGGGGGCAGTGGTTTACTTTTCCCTTTTTTCTTCCTTTCTTTTGTCCTCTCAGCTGCCCACAG
CCAGAAAGCCAGGACCACCCGAACTGGACAGGGAGCAGGGAGGGAGGAGTGGTCGCACGGAGCGTACCTGATTCAACAGGAAATCAGTTA
TTTTCTAAAACAGCCCCTACCAGAGCCTCCTGAACTCTGTGGGCACCACGTGCTGCTGTGAGCATCTGCCCAGACAGTGACCCGCCACAG
GCCCCGGGCGTCTGTGGAAGGAGTTTTGTAAAGGAAAAAAAAACACACACACACAAACATTTTTTCAATGTAGCAAAATCAAACTTAAAA
AAAAAAAAGAAGAAAAGAAGAAGATGCCGACAGTGCGGAGTCTAGCCTTTTGTAAACTTCATATTGCACACTAGGACTATAAGCCATTGC
TAGCTCATTTTGAATTTTAACGTGTAATTTTTGTTTTATTTTCTTTCTGTGGGGAAACAATGCTTGATCCACCAATGCTCTTTTTAATGT
TTTATAACTATGTATGTGTATATATATAAATATCAAATAATATGTATGCACATATGTGTGTGTATATATCTATATGTATATACATATATA
GATATATAGAGATATATAGAGAGGTTTTGAGACAAAAAAAATACAGAACGTGAAACCCGAGCTGAACAGCGTGTGCTCTGATTACTTGAA
TCTGGTCTCCTCGGCACCTGGTTATTAAGAACTGAATATTTTTCCACTTGAATTTAGTGCTATTAGAAATTTAATATATGTGTTTTATTT

>In-frame_OBSCN_ENST00000284548_chr1_228412435_+_CASZ1_ENST00000344008_chr1_10725628_-_7072nt
TGCCTCCCAGCCTGTGCCCCCAGCCTGCGTGCTGCCCAGAGCCCCCATAGAGAGAGGTCCCCGCCGCCACCCTCATGGATCAGCCACAGT
TCAGCGGGGCGCCCCGCTTTCTCACCCGGCCCAAGGCCTTCGTGGTGTCGGTGGGCAAGGACGCCACCCTCAGCTGCCAGATCGTGGGTA
ATCCCACGCCACAGGTGAGCTGGGAGAAGGACCAGCAGCCGGTGGCGGCCGGCGCGCGCTTCCGTCTGGCCCAGGACGGCGACCTCTACC
GCCTCACTATCCTGGACCTGGCGCTGGGCGACAGTGGGCAATACGTGTGCCGCGCGCGCAATGCCATAGGCGAGGCCTTCGCTGCTGTGG
GCCTGCAGGTGGACGCGGAGGCCGCGTGCGCCGAGCAGGCGCCGCACTTCCTGCTGCGGCCCACGTCCATCCGCGTGCGCGAGGGCTCAG
AGGCCACCTTCCGCTGCCGCGTGGGTGGCTCCCCGAGGCCGGCAGTGAGCTGGTCCAAGGACGGGCGGCGCCTGGGTGAGCCCGACGGCC
CCCGCGTGCGCGTGGAGGAGCTCGGCGAGGCAAGTGCGCTGCGCATTCGGGCGGCGCGGCCGCGCGACGGCGGCACTTACGAGGTCCGCG
CCGAGAACCCGCTGGGCGCTGCCAGCGCCGCCGCGGCGCTAGTGGTGGACTCGGACGCCGCGGACACGGCCAGCCGGCCCGGGACCTCCA
CGGCCGCGCTCCTGGCGCACCTGCAGCGGCGGCGCGAGGCTATGCGCGCCGAGGGCGCCCCCGCCTCACCGCCCAGCACCGGCACGCGCA
CCTGCACGGTGACTGAAGGCAAGCACGCGCGCCTCAGCTGCTACGTGACCGGCGAGCCCAAGCCCGAGACGGTGTGGAAGAAGGACGGCC
AGCTGGTGACCGAGGGCCGGCGCCACGTGGTGTACGAGGACGCGCAGGAGAACTTCGTGCTCAAGATCCTCTTCTGCAAGCAGTCGGACC
GCGGCCTCTACACCTGCACGGCGTCCAACCTCGTGGGCCAGACCTACAGCTCTGTGCTGGTCGTAGTGCGCGAGCCCGCGGTTCCCTTCA
AAAAGCGGCTGCAAGATCTGGAGGTGCGGGAGAAGGAGTCGGCCACGTTCCTATGTGAGGTGCCCCAGCCGTCCACTGAGGCCGCGTGGT
TCAAGGAGGAGACGCGGTTGTGGGCGAGCGCCAAGTACGGCATCGAGGAGGAGGGCACCGAGCGCCGCCTGACCGTGCGCAATGTCTCGG
CCGACGACGACGCGGTGTACATCTGCGAGACGCCAGAGGGCAGCCGCACGGTGGCGGAGCTCGCAGTCCAAGGAAACCTCCTCCGAAAGC
TCCCTCGGAAGACGGCGGTGCGCGTGGGCGACACGGCTATGTTTTGCGTGGAGCTGGCGGTCCCGGTGGGCCCCGTCCACTGGCTGCGGA
ACCAGGAGGAAGTGGTGGCGGGGGGCCGCGTGGCCATCTCCGCGGAGGGCACGCGCCACACACTAACCATCTCCCAGTGCTGCCTGGAGG
ATGTGGGCCAGGTGGCCTTTATGGCTGGCGACTGCCAGACGTCCACCCAGTTCTGCGTGTCGGCCCCCAGGAAGCCTCCCCTGCAACCCC
CTGTGGATCCTGTGGTAAAGGCCAGGATGGAGAGTTCCGTGATTCTCAGCTGGTCCCCACCACCCCATGGGGAACGCCCTGTCACTATCG
ACGGCTACCTGGTAGAGAAGAAGAAGCTTGGCACCTACACCTGGATCAGGTGCCACGAGGCTGAATGGGTGGCTACACCTGAGCTGACCG
TGGCTGATGTGGCGGAGGAGGGGAACTTCCAGTTCCGAGTGTCCGCTCTCAACAGCTTTGGTCAGAGTCCCTACCTCGAGTTCCCGGGGA
CTGTCCACCTGGCCCCCAAGCTGGCCGTGAGGACACCGCTGAAGGCGGTGCAGGCGGTAGAGGGTGGCGAGGTCACTTTCTCCGTGGACC
TCACGGTGGCCTCAGCGGGTGAGTGGTTCCTGGATGGGCAGGCCCTGAAGGCCAGCAGTGTGTATGAGATCCACTGTGATCGCACCCGGC
ACACGCTCACCATCCGGGAGGTGCCCGCCAGCCTGCACGGGGCGCAGCTGAAGTTCGTGGCCAACGGCATTGAGAGCAGCATCCGGATGG
AGGTCCGGGCGGCCCCAGGGCTGACTGCCAACAAGCCGCCAGCCGCAGCTGCCCGGGAGGTGCTGGCTCGGCTGCACGAGGAGGCGCAGC
TGCTGGCTGAGCTGTCAGATCAGGCTGCGGCTGTGACGTGGCTGAAGGATGGTCGCACACTGTCCCCAGGCCCCAAGTATGAGGTGCAGG
CATCGGCCGGGCGGCGGGTGCTCCTTGTGCGAGATGTGGCCCGGGACGATGCAGGCCTCTACGAGTGCGTCAGCCGCGGGGGCCGCATCG
CCTACCAGCTCTCCGTGCAAGGCCTCGCGCGCTTTCTGCACAAGGACATGGCGGGCAGCTGTGTGGATGCCGTGGCTGGGGGCCCGGCGC
AGTTTGAGTGTGAGACCTCCGAAGCCCACGTCCACGTGCACTGGTACAAGGATGGCATGGAGCTGGGCCACTCCGGTGAGCGCTTCTTGC
AGGAGGATGTGGGGACGCGGCACCGGCTGGTGGCAGCCACAGTCACCAGGCAGGATGAAGGCACCTACTCCTGCCGCGTGGGCGAGGACT
CTGTGGACTTCCGGCTCCGCGTCTCTGAGCCCAAGGTGGTGTTTGCTAAGGAGCAGCTGGCACGCAGGAAGCTGCAGGCAGAGGCAGGAG
CCAGTGCCACACTGAGCTGCGAGGTGGCCCAGGCCCAGACGGAGGTGACGTGGTACAAGGATGGGAAGAAGCTGAGCTCCAGCTCGAAAG
TGTGCATGGAGGCCACAGGCTGCACGCGCAGGCTGGTTGTGCAGCAGGCAGGCCAGGCGGATGCCGGGGAGTATAGCTGCGAGGCTGGGG
GCCAGCGGCTCTCCTTCCATCTGGATGTCAAAGCTGAGGGCACCCGGTGCACGGACCCGCCTGCAGGCAAGCCCGCCATGGCGCCCAAAC
GCAAGGGTGGCCTGAAGCTGAACGCCATCTGCGCCAAGCTGAGCCGCCAGGTGGTGGTGGAGAAGCGAGCTGACGCCGGCTCCCACACGG
AGGGCAGCCCATCGCAGCCCCGGGACCAAGAGCGCAGTGGCCCTGAGTCTGGGGCAGCCCGGGCCCCCCGCAGCGAGGAAGACAAGAGAC
GGGCAGTGATCGAGAAGTGGGTGAACGGGGAGTACAGCGAGGAGCCGGCACCCACACCCGTGTTGGGGCGGATTGCCCGCGAGGGCCTGG
AGCTGCCTCCCGAGGGTGTCTACATGGTGCAGCCCCAGGGGTGCAGCGATGAGGAAGACCACGCGGAGGAGCCCTCCAAGGACGGCGGTG
CCCTGGAGGAGAAGGATTCGGACGGGGCAGCCTCCAAGGAGGACAGCGGCCCCAGCACCAGGCAGGCTTCAGGAGAGGCCTCCTCGCTGC
GGGACTACGCGGCCTCCACCATGACCGAGTTCCTCGGCATGTTTGGCTATGATGACCAGAACACGCGGGACGAGCTGGCCAGGAAGATCA
GCTTTGAGAAGCTGCACGCGGGCTCCACCCCGGAGGCAGCCACCTCCTCCATGCTGCCCACCTCCGAGGATACCCTCAGCAAGCGGGCGC
GGTTCTCTAAGTATGAGGAGTACATCCGCAAGCTCAAGGCTGGCGAGCAGCTCTCCTGGCCGGCCCCCAGCACCAAGACCGAGGAGCGGG
TGGGCAAGGAGGTGGTGGGCACCCTGCCCGGCCTGCGGCTGCCCAGCAGCACGGCCCACCTGGAGACCAAGGCCACCATCCTGCCCCTGC
CGTCGCACAGCAGTGTCCAGATGCAGAACCTGGTAGCCCGGGCCTCCAAGTACGACTTCTTCATCCAAAAACTGAAGACCGGCGAGAATC
TGCGGCCCCAGAACGGGAGCACCTACAAGAAGCCATCCAAGTACGACCTGGAGAATGTCAAGTACCTGCACCTCTTCAAACCCGGGGAGG
GCAGCCCCGACATGGGCGGGGCCATCGCCTTCAAGACAGGCAAGGTGGGGCGCCCTTCCAAGTACGACGTCCGGGGCATCCAGAAGCCAG
GCCCCGCCAAGGTTCCGCCCACCCCCAGCCTGGCTCCCGCACCCCTCGCCAGCGTGCCCAGTGCCCCCAGCGCCCCCGGGCCAGGGCCAG
AGCCTCCTGCCTCCCTGTCCTTCAACACTCCCGAGTACCTGAAGTCAACCTTCTCCAAAACAGACTCCATCACCACGGGGACCGTCTCCA
CTGTCAAGAACGGACTGCCCACAGATAAACCAGCCGTCACTGAAGATGTAAACATTTACCAGAAATATATTGCCAGGTTCTCGGGCAGCC
AGCACTGTGGCCACATCCACTGTGCCTACCAGTACCGCGAGCACTACCACTGCCTTGACCCTGAGTGTAACTACCAGAGGTTCACGAGTA
AGCAGGACGTGATCCGCCACTACAACATGCACAAGAAGCGCGACAACTCCCTGCAGCACGGCTTCATGCGTTTCAGCCCGCTGGACGACT
GCAGCGTCTACTACCACGGCTGCCACCTCAATGGGAAGAGCACCCACTATCACTGCATGCAGGTGGGCTGTAACAAGGTGTACACGAGCA
CGTCTGACGTGATGACCCACGAGAACTTCCACAAGAAGAATACCCAGCTCATTAACGACGGCTTCCAGCGCTTCCGAGCCACCGAAGACT
GTGGCACAGCCGACTGCCAGTTCTACGGACAGAAGACCACGCACTTCCACTGCAGGCGCCCCGGCTGCACATTCACTTTCAAGAACAAGT
GTGACATCGAGAAGCACAAGAGCTACCACATCAAGGACGATGCCTACGCCAAGGACGGCTTCAAGAAGTTCTACAAGTACGAGGAGTGCA
AGTACGAGGGCTGCGTGTACAGCAAGGCTACCAACCACTTCCACTGCATCCGCGCCGGCTGCGGCTTCACCTTCACCTCCACCAGCCAGA
TGACCTCTCACAAGCGCAAGCATGAGCGCCGGCACATCCGCTCCTCGGGCGCGCTGGGGCTGCCGCCCTCGCTGCTGGGCGCCAAGGACA
CGGAGCACGAGGAGTCCAGCAACGACGACCTTGTTGACTTCTCCGCCCTGAGCAGCAAGAACTCCAGCCTGAGCGCCTCCCCTACCAGCC
AGCAGTCCTCTGCGTCCCTGGCTGCCGCCACTGCCGCCACCGAGGCTGGGCCCAGTGCCACCAAACCTCCCAACAGCAAGATCTCGGGGC
TGCTGCCCCAGGGCCTGCCTGGCTCAATCCCCCTGGCCCTGGCCCTCTCCAACTCGGGCCTGCCCACCCCCACGCCCTACTTCCCCATAC
TGGCTGGCCGTGGGAGCACCTCCCTGCCTGTGGGCACCCCCAGCCTCCTGGGTGCCGTGTCGTCTGGGTCAGCAGCCTCAGCCACCCCTG
ACACACCCACGCTGGTCGCCTCGGGAGCTGGAGACTCAGCCCCCGTGGCTGCCGCCTCTGTCCCGGCACCACCCGCCTCCATCATGGAGA
GGATCTCTGCAAGCAAGGGCCTCATCTCGCCCATGATGGCCAGGCTGGCTGCAGCTGCCCTCAAGCCCTCTGCCACCTTTGACCCAGGAA
GCGGGCAGCAGGTCACCCCAGCCAGGTTCCCCCCGGCCCAAGTGAAGCCGGAACCCGGTGAGAGCACCGGCGCCCCAGGCCCCCACGAAG
CCTCCCAGGACCGCAGTCTAGACCTGACTGTGAAGGAGCCCAGCAACGAATCAAATGGCCACGCAGTCCCGGCAAATTCATCTCTTTTAT
CCTCGCTTATGAATAAGATGTCTCAGGGCAACCCTGGCCTGGGCAGCCTGCTGAACATCAAGGCGGAAGCGGAGGGGAGCCCCGCTGCGG
AGCCCTCGCCCTTCCTAGGCAAGGCCGTGAAGGCGCTGGTTCAGGAGAAGTTGGCAGAGCCCTGGAAGGTGTACCTGCGCAGGTTTGGTA
CAAAGGACTTCTGTGACGGCCAGTGTGACTTCCTCCACAAGGCCCACTTCCACTGCGTGGTGGAGGAATGCGGCGCGCTCTTCAGCACCT
TGGACGGGGCCATCAAGCACGCAAACTTCCACTTCCGGACAGAGGGAGGAGCAGCAAAAGGAAACACAGAGGCTGCCTTTCCGGCCTCGG
CCGCCGAGACCAAACCTCCCATGGCCCCCTCGTCCCCTCCGGTCCCTCCTGTCACCACGGCCACGGTGTCCTCTCTGGAGGGGCCCGCTC
CCAGCCCGGCCTCCGTGCCCTCCACCCCCACCCTGCTCGCCTGGAAGCAGCTGGCTTCCACCATACCCCAGATGCCTCAGATCCCAGCGT
CAGTGCCTCACCTGCCCGCCTCGCCCTTGGCAACGACTTCTCTAGAGAACGCCAAGCCCCAGGTCAAACCCGGATTCCTCCAGTTCCAGG
AGAAGTGAGTCCCTCGATGAGCCGGGAGTCCCGCGTTCCCCTCGCGTCTCGGGAGTAGGTGCTAGCAAGGGCGCTAGGAGGCCCTGTTCC
TCACTGCGGATGGTGCTGCTGTCCCCAGCCTCTCTGGGGCATGGCCATCGGGTGATGTCCTTCTAGCCAAAGATGCTGCTGCTCCTACCT
CACTGCCTGTCCCAGAGCAGGCCAGCCCGCGTGGGCCGATGGTGGCGGCAGTGGCTACTGCTCCTGCAGGGCATGTGGTGATCCTGCCAG
GGCCAGGTGGGGTGGACTGGGCGTGGTGGTCCTCAGAGGACAACTCCCAGCCTGACAAGGAGGGCTGCGTCTCCCTCCGAGCCTCCGTAT
TGGCCTCCTCTGTGGCTCACACCCATGGCTGAATCTCTGCAGGGCACGTGAAGTCACGGGTAGGGGCCAGGCCCCTCCAGGCCGTCACTG
GCCTGCACAGTGGTCTGAGCTCTTGGGTGGAAGGGACCCTCCTCACTGGATGGTGGTGGCTCCTTGCAGGGAGAACGGTGACTTTGTATT

>In-frame_OBSCN_ENST00000570156_chr1_228412435_+_CASZ1_ENST00000377022_chr1_10725628_-_10881nt
TGCCTCCCAGCCTGTGCCCCCAGCCTGCGTGCTGCCCAGAGCCCCCATAGAGAGAGGTCCCCGCCGCCACCCTCATGGATCAGCCACAGT
TCAGCGGGGCGCCCCGCTTTCTCACCCGGCCCAAGGCCTTCGTGGTGTCGGTGGGCAAGGACGCCACCCTCAGCTGCCAGATCGTGGGTA
ATCCCACGCCACAGGTGAGCTGGGAGAAGGACCAGCAGCCGGTGGCGGCCGGCGCGCGCTTCCGTCTGGCCCAGGACGGCGACCTCTACC
GCCTCACTATCCTGGACCTGGCGCTGGGCGACAGTGGGCAATACGTGTGCCGCGCGCGCAATGCCATAGGCGAGGCCTTCGCTGCTGTGG
GCCTGCAGGTGGACGCGGAGGCCGCGTGCGCCGAGCAGGCGCCGCACTTCCTGCTGCGGCCCACGTCCATCCGCGTGCGCGAGGGCTCAG
AGGCCACCTTCCGCTGCCGCGTGGGTGGCTCCCCGAGGCCGGCAGTGAGCTGGTCCAAGGACGGGCGGCGCCTGGGTGAGCCCGACGGCC
CCCGCGTGCGCGTGGAGGAGCTCGGCGAGGCAAGTGCGCTGCGCATTCGGGCGGCGCGGCCGCGCGACGGCGGCACTTACGAGGTCCGCG
CCGAGAACCCGCTGGGCGCTGCCAGCGCCGCCGCGGCGCTAGTGGTGGACTCGGACGCCGCGGACACGGCCAGCCGGCCCGGGACCTCCA
CGGCCGCGCTCCTGGCGCACCTGCAGCGGCGGCGCGAGGCTATGCGCGCCGAGGGCGCCCCCGCCTCACCGCCCAGCACCGGCACGCGCA
CCTGCACGGTGACTGAAGGCAAGCACGCGCGCCTCAGCTGCTACGTGACCGGCGAGCCCAAGCCCGAGACGGTGTGGAAGAAGGACGGCC
AGCTGGTGACCGAGGGCCGGCGCCACGTGGTGTACGAGGACGCGCAGGAGAACTTCGTGCTCAAGATCCTCTTCTGCAAGCAGTCGGACC
GCGGCCTCTACACCTGCACGGCGTCCAACCTCGTGGGCCAGACCTACAGCTCTGTGCTGGTCGTAGTGCGCGAGCCCGCGGTTCCCTTCA
AAAAGCGGCTGCAAGATCTGGAGGTGCGGGAGAAGGAGTCGGCCACGTTCCTATGTGAGGTGCCCCAGCCGTCCACTGAGGCCGCGTGGT
TCAAGGAGGAGACGCGGTTGTGGGCGAGCGCCAAGTACGGCATCGAGGAGGAGGGCACCGAGCGCCGCCTGACCGTGCGCAATGTCTCGG
CCGACGACGACGCGGTGTACATCTGCGAGACGCCAGAGGGCAGCCGCACGGTGGCGGAGCTCGCAGTCCAAGGAAACCTCCTCCGAAAGC
TCCCTCGGAAGACGGCGGTGCGCGTGGGCGACACGGCTATGTTTTGCGTGGAGCTGGCGGTCCCGGTGGGCCCCGTCCACTGGCTGCGGA
ACCAGGAGGAAGTGGTGGCGGGGGGCCGCGTGGCCATCTCCGCGGAGGGCACGCGCCACACACTAACCATCTCCCAGTGCTGCCTGGAGG
ATGTGGGCCAGGTGGCCTTTATGGCTGGCGACTGCCAGACGTCCACCCAGTTCTGCGTGTCGGCCCCCAGGAAGCCTCCCCTGCAACCCC
CTGTGGATCCTGTGGTAAAGGCCAGGATGGAGAGTTCCGTGATTCTCAGCTGGTCCCCACCACCCCATGGGGAACGCCCTGTCACTATCG
ACGGCTACCTGGTAGAGAAGAAGAAGCTTGGCACCTACACCTGGATCAGGTGCCACGAGGCTGAATGGGTGGCTACACCTGAGCTGACCG
TGGCTGATGTGGCGGAGGAGGGGAACTTCCAGTTCCGAGTGTCCGCTCTCAACAGCTTTGGTCAGAGTCCCTACCTCGAGTTCCCGGGGA
CTGTCCACCTGGCCCCCAAGCTGGCCGTGAGGACACCGCTGAAGGCGGTGCAGGCGGTAGAGGGTGGCGAGGTCACTTTCTCCGTGGACC
TCACGGTGGCCTCAGCGGGTGAGTGGTTCCTGGATGGGCAGGCCCTGAAGGCCAGCAGTGTGTATGAGATCCACTGTGATCGCACCCGGC
ACACGCTCACCATCCGGGAGGTGCCCGCCAGCCTGCACGGGGCGCAGCTGAAGTTCGTGGCCAACGGCATTGAGAGCAGCATCCGGATGG
AGGTCCGGGCGGCCCCAGGGCTGACTGCCAACAAGCCGCCAGCCGCAGCTGCCCGGGAGGTGCTGGCTCGGCTGCACGAGGAGGCGCAGC
TGCTGGCTGAGCTGTCAGATCAGGCTGCGGCTGTGACGTGGCTGAAGGATGGTCGCACACTGTCCCCAGGCCCCAAGTATGAGGTGCAGG
CATCGGCCGGGCGGCGGGTGCTCCTTGTGCGAGATGTGGCCCGGGACGATGCAGGCCTCTACGAGTGCGTCAGCCGCGGGGGCCGCATCG
CCTACCAGCTCTCCGTGCAAGGCCTCGCGCGCTTTCTGCACAAGGACATGGCGGGCAGCTGTGTGGATGCCGTGGCTGGGGGCCCGGCGC
AGTTTGAGTGTGAGACCTCCGAAGCCCACGTCCACGTGCACTGGTACAAGGATGGCATGGAGCTGGGCCACTCCGGTGAGCGCTTCTTGC
AGGAGGATGTGGGGACGCGGCACCGGCTGGTGGCAGCCACAGTCACCAGGCAGGATGAAGGCACCTACTCCTGCCGCGTGGGCGAGGACT
CTGTGGACTTCCGGCTCCGCGTCTCTGAGCCCAAGGCGGTGTTTGCCAAGGAGCAGCCGGCGTGCAGGGAGGTGCAGGCTGAGGTGGGGG
CCAGCGCCACGCTGAGCTGTGAGGTGGCCCAGGACCAGATGGAGGTGACGTGGTACAAGGACGGGAAGAAGTTGAGCTCCAGCTCGAAAG
TGCACGTGGAGGCTGTGGGCTGTATGCGGAGGCTGGTGGTGCAGCAGGTGGGCCAGGCAGACTCCGGAGAGTACAGCTGTGAGGCCAGGG
GACAGAGGGTCTCCTTCCGCCTGGACGTTGCAGAGCCCAAGGTGGTGTTTGCTAAGGAGCAGCTGGCACGCAGGAAGCTGCAGGCAGAGG
CAGGAGCCAGTGCCACACTGAGCTGCGAGGTGGCCCAGGCCCAGACGGAGGTGACGTGGTACAAGGATGGGAAGAAGCTGAGCTCCAGCT
CGAAAGTGTGCATGGAGGCCACAGGCTGCACGCGCAGGCTGGTTGTGCAGCAGGCAGGCCAGGCGGATGCCGGGGAGTATAGCTGCGAGG
CTGGGGGCCAGCGGCTCTCCTTCCATCTGGATGTCAAAGCTGAGGGCACCCGGTGCACGGACCCGCCTGCAGGCAAGCCCGCCATGGCGC
CCAAACGCAAGGGTGGCCTGAAGCTGAACGCCATCTGCGCCAAGCTGAGCCGCCAGGTGGTGGTGGAGAAGCGAGCTGACGCCGGCTCCC
ACACGGAGGGCAGCCCATCGCAGCCCCGGGACCAAGAGCGCAGTGGCCCTGAGTCTGGGGCAGCCCGGGCCCCCCGCAGCGAGGAAGACA
AGAGACGGGCAGTGATCGAGAAGTGGGTGAACGGGGAGTACAGCGAGGAGCCGGCACCCACACCCGTGTTGGGGCGGATTGCCCGCGAGG
GCCTGGAGCTGCCTCCCGAGGGTGTCTACATGGTGCAGCCCCAGGGGTGCAGCGATGAGGAAGACCACGCGGAGGAGCCCTCCAAGGACG
GCGGTGCCCTGGAGGAGAAGGATTCGGACGGGGCAGCCTCCAAGGAGGACAGCGGCCCCAGCACCAGGCAGGCTTCAGGAGAGGCCTCCT
CGCTGCGGGACTACGCGGCCTCCACCATGACCGAGTTCCTCGGCATGTTTGGCTATGATGACCAGAACACGCGGGACGAGCTGGCCAGGA
AGATCAGCTTTGAGAAGCTGCACGCGGGCTCCACCCCGGAGGCAGCCACCTCCTCCATGCTGCCCACCTCCGAGGATACCCTCAGCAAGC
GGGCGCGGTTCTCTAAGTATGAGGAGTACATCCGCAAGCTCAAGGCTGGCGAGCAGCTCTCCTGGCCGGCCCCCAGCACCAAGACCGAGG
AGCGGGTGGGCAAGGAGGTGGTGGGCACCCTGCCCGGCCTGCGGCTGCCCAGCAGCACGGCCCACCTGGAGACCAAGGCCACCATCCTGC
CCCTGCCGTCGCACAGCAGTGTCCAGATGCAGAACCTGGTAGCCCGGGCCTCCAAGTACGACTTCTTCATCCAAAAACTGAAGACCGGCG
AGAATCTGCGGCCCCAGAACGGGAGCACCTACAAGAAGCCATCCAAGTACGACCTGGAGAATGTCAAGTACCTGCACCTCTTCAAACCCG
GGGAGGGCAGCCCCGACATGGGCGGGGCCATCGCCTTCAAGACAGGCAAGGTGGGGCGCCCTTCCAAGTACGACGTCCGGGGCATCCAGA
AGCCAGGCCCCGCCAAGGTTCCGCCCACCCCCAGCCTGGCTCCCGCACCCCTCGCCAGCGTGCCCAGTGCCCCCAGCGCCCCCGGGCCAG
GGCCAGAGCCTCCTGCCTCCCTGTCCTTCAACACTCCCGAGTACCTGAAGTCAACCTTCTCCAAAACAGACTCCATCACCACGGGGACCG
TCTCCACTGTCAAGAACGGACTGCCCACAGATAAACCAGCCGTCACTGAAGATGTAAACATTTACCAGAAATATATTGCCAGGTTCTCGG
GCAGCCAGCACTGTGGCCACATCCACTGTGCCTACCAGTACCGCGAGCACTACCACTGCCTTGACCCTGAGTGTAACTACCAGAGGTTCA
CGAGTAAGCAGGACGTGATCCGCCACTACAACATGCACAAGAAGCGCGACAACTCCCTGCAGCACGGCTTCATGCGTTTCAGCCCGCTGG
ACGACTGCAGCGTCTACTACCACGGCTGCCACCTCAATGGGAAGAGCACCCACTATCACTGCATGCAGGTGGGCTGTAACAAGGTGTACA
CGAGCACGTCTGACGTGATGACCCACGAGAACTTCCACAAGAAGAATACCCAGCTCATTAACGACGGCTTCCAGCGCTTCCGAGCCACCG
AAGACTGTGGCACAGCCGACTGCCAGTTCTACGGACAGAAGACCACGCACTTCCACTGCAGGCGCCCCGGCTGCACATTCACTTTCAAGA
ACAAGTGTGACATCGAGAAGCACAAGAGCTACCACATCAAGGACGATGCCTACGCCAAGGACGGCTTCAAGAAGTTCTACAAGTACGAGG
AGTGCAAGTACGAGGGCTGCGTGTACAGCAAGGCTACCAACCACTTCCACTGCATCCGCGCCGGCTGCGGCTTCACCTTCACCTCCACCA
GCCAGATGACCTCTCACAAGCGCAAGCATGAGCGCCGGCACATCCGCTCCTCGGGCGCGCTGGGGCTGCCGCCCTCGCTGCTGGGCGCCA
AGGACACGGAGCACGAGGAGTCCAGCAACGACGACCTTGTTGACTTCTCCGCCCTGAGCAGCAAGAACTCCAGCCTGAGCGCCTCCCCTA
CCAGCCAGCAGTCCTCTGCGTCCCTGGCTGCCGCCACTGCCGCCACCGAGGCTGGGCCCAGTGCCACCAAACCTCCCAACAGCAAGATCT
CGGGGCTGCTGCCCCAGGGCCTGCCTGGCTCAATCCCCCTGGCCCTGGCCCTCTCCAACTCGGGCCTGCCCACCCCCACGCCCTACTTCC
CCATACTGGCTGGCCGTGGGAGCACCTCCCTGCCTGTGGGCACCCCCAGCCTCCTGGGTGCCGTGTCGTCTGGGTCAGCAGCCTCAGCCA
CCCCTGACACACCCACGCTGGTCGCCTCGGGAGCTGGAGACTCAGCCCCCGTGGCTGCCGCCTCTGTCCCGGCACCACCCGCCTCCATCA
TGGAGAGGATCTCTGCAAGCAAGGGCCTCATCTCGCCCATGATGGCCAGGCTGGCTGCAGCTGCCCTCAAGCCCTCTGCCACCTTTGACC
CAGGAAGCGGGCAGCAGGTCACCCCAGCCAGGTTCCCCCCGGCCCAAGTGAAGCCGGAACCCGGTGAGAGCACCGGCGCCCCAGGCCCCC
ACGAAGCCTCCCAGGACCGCAGTCTAGACCTGACTGTGAAGGAGCCCAGCAACGAATCAAATGGCCACGCAGTCCCGGCAAATTCATCTC
TTTTATCCTCGCTTATGAATAAGATGTCTCAGGGCAACCCTGGCCTGGGCAGCCTGCTGAACATCAAGGCGGAAGCGGAGGGGAGCCCCG
CTGCGGAGCCCTCGCCCTTCCTAGGCAAGGCCGTGAAGGCGCTGGTTCAGGAGAAGTTGGCAGAGCCCTGGAAGGTGTACCTGCGCAGGT
TTGGTACAAAGGACTTCTGTGACGGCCAGTGTGACTTCCTCCACAAGGCCCACTTCCACTGCGTGGTGGAGGAATGCGGCGCGCTCTTCA
GCACCTTGGACGGGGCCATCAAGCACGCAAACTTCCACTTCCGGACAGAGGGAGGAGCAGCAAAAGGAAACACAGAGGCTGCCTTTCCGG
CCTCGGCCGCCGAGACCAAACCTCCCATGGCCCCCTCGTCCCCTCCGGTCCCTCCTGTCACCACGGCCACGGTGTCCTCTCTGGAGGGGC
CCGCTCCCAGCCCGGCCTCCGTGCCCTCCACCCCCACCCTGCTCGCCTGGAAGCAGCTGGCTTCCACCATACCCCAGATGCCTCAGATCC
CAGCGTCAGTGCCTCACCTGCCCGCCTCGCCCTTGGCAACGACTTCTCTAGAGAACGCCAAGCCCCAGGTCAAACCCGGATTCCTCCAGT
TCCAGGAGAACGATCCTTGCCTCGCCACGGACTGCAAGTACGCCAACAAGTTCCACTTCCACTGTCTCTTTGGGAACTGCAAGTACGTCT
GCAAAACGTCTGGCAAGGCCGAATCCCACTGCCTGGACCACATCAACCCCAACAACAACCTGGTGAACGTGCGAGACCAGTTTGCATACT
ACTCTCTGCAGTGTCTCTGTCCCAACCAGCACTGCGAGTTCCGAATGCGTGGGCACTACCACTGCCTCCGCACCGGCTGCTATTTTGTGA
CCAACATCACCACCAAGCTCCCCTGGCACATCAAGAAGCATGAGAAGGCGGAGCGGCGGGCAGCCAATGGCTTCAAATACTTCACCAAGC
GCGAGGAGTGTGGCAGGCTAGGTTGCAAGTACAACCAGGTGAACAGCCACTTCCACTGCATCCGGGAGGGCTGCCAGTTCTCCTTCCTCC
TCAAGCACCAGATGACCTCCCACGCGCGGAAGCACATGCGGAGGATGCTGGGGAAGAACTTCGACCGCGTGCCCCCCTCCCAGGGCCCCC
CAGGCCTGATGGATGCTGAGACAGATGAGTGCATGGACTACACTGGCTGCAGCCCAGGCGCCATGTCCTCTGAGTCATCCACCATGGACC
GGAGCTGCTCCAGCACCCCCGTGGGTAACGAGAGCACCGCGGCAGGGAACACCATCTCTATGCCGACAGCCTCGGGGGCCAAAAAGCGCT
TCTGGATCATCGAGGACATGTCGCCCTTCGGCAAGCGGCGGAAGACGGCGTCCTCCCGGAAGATGCTGGACGAGGGCATGATGCTGGAGG
GCTTCCGGCGCTTCGACCTTTACGAGGACTGCAAGGACGCAGCTTGTCAGTTCTCGCTCAAGGTCACCCACTACCACTGCACGCGCGAGA
ACTGCGGCTACAAGTTCTGCGGGCGCACGCACATGTACAAGCACGCGCAGCACCACGACCGCGTGGACAACCTGGTGCTGGACGACTTCA
AGCGCTTCAAGGCCTCACTCAGCTGCCACTTCGCCGACTGCCCCTTCTCGGGCACCAGCACGCACTTCCACTGCCTGCGCTGCCGCTTCC
GCTGCACCGACAGCACCAAGGTCACGGCGCATCGCAAGCACCACGGCAAACAGGACGTGATCAGCGCCGCGGGCTTCTGCCAGTTCAGCT
CCAGCGCCGACTGCGCCGTGCCCGACTGCAAGTACAAGCTCAAGTGCTCGCACTTCCACTGCACCTTCCCGGGCTGCCGCCACACGGTGG
TGGGCATGTCGCAGATGGACTCGCACAAGCGCAAGCACGAGAAGCAGGAGCGCGGCGAGCCCGCGGCAGAGGGCCCCGCGCCCGGGCCTC
CCATCAGTCTGGACGGCTCCCTGTCGCTGGGCGCCGAGCCGGGCTCGCTGCTCTTCCTGCAGTCGGCGGCCGCCGGCCTGGGCCTGGCGC
TGGGCGACGCGGGCGACCCCGGCCCGCCCGACGCCGCCGCCCCCGGGCCGCGCGAGGGCGCCGCCGCCGCCGCCGCCGCAGCTGGGGAGT
CCTCGCAGGAGGACGAGGAGGAGGAGCTGGAGCTGCCGGAGGAGGAGGCCGAAGACGACGAGGACGAGGACGACGACGAGGACGACGACG
ACGAGGACGACGACGAGGACGACGACGACGAGGACCTGCGCACCGACTCGGAGGAGTCGCTGCCCGAGGCGGCGGCGGAGGCGGCGGGCG
CGGGCGCGCGGACCCCGGCCTTGGCGGCGCTGGCGGCCCTGGGCGCCCCCGGCCCCGCGCCCACTGCAGCCTCCTCGCCCTAGCGGCGCC
CGCGGGTGGCCCTGGCGGCGGCCTCGGCCTCGGCCTCGGGAGCGGCGCCGCCCCGCGCGAAGCGGCCCCTGGGCAGAGCCCCGCGCCCCG
CCGGTGCTTCCGGACCCCGAGTCCGTCTCAGGACAGAGGCGGGGACCCCTCTGGTGCTCCGCGGCCGAGGACACAGGCGGCGGCGGTGGC
CCTGCTCTAGGGAGGCCGGGTCTCTTCAGGGAAACAGAAGGTGCTCTTGTCCCGGGGTAGGGAACCTAGGAGCAGGGGTCCCGGGCGAAT
GCGGCGCAGCTCCCGGCCGCTGCCCCGGCGCCCCTCCCCGCGGCCGATTCGGCCCCGCGACCATTGCTCAGGACTGGGACGGGCGCTGGG
GGCCACCGGGACCCCCACCGCGCGCCACCAGGGCGGGGTGGCTCCTGGAGCCGCTGGCGGGGCCTCCCTCATGCAGCTAGGATCCTCCCC
CCTGCCCAGGGGGAGACGGGCAGAAGGCAGTCAGCACGGGTGACACTACAGGGACCGTGGAGGAAGCCTCACGGGAGTAGCAGCCGCGGA
GCTCCAGCTCAGCCCCACCCCAGGGCCCGGCTGCTCCCCCAGGCCTGGGTCGGGTCTGTTTGGCGACTCCCTGGCCCCAGCCTCCGCCCC
AGGGAAACCGAGGCTGCGTCCAAAACCCAGAGTAGCCCGCTGGGGGCCGGGGCGGGGTCTCGGCCACCCTGGTGGTGCAAACAGGAAGGA
TGCGCCTGGTTTTGGCTTTAATGTTCAAAATGGAAAAAAATACAAGAAAGTTGTACAGTATTTTTCCTGTAAAGGTTATTATTCTACATA
GAACAAAAAGGAAGAAAGCAGGCGTGGTGAGAGTGCAGACCCGCCTGGGCCCGGCCTGAGGTTGGAGGCTCAGTCCCGTTTATCCTGTGG
GATTTGGTCCAGGGTTTTTGTAGAGGCCTTAACTGTTTGAGGCTGTCTGTCTTCACAATAGCACTGATGGGAGCTGCGTGATTCCAACTC
TTAACTTGAATTTTGTAGAGACAAGAAAAAAGGACTATTACTGTTGATCCAAGTTTGTAGTTAATTTAACATTTGAGTTCTCTCTTGGTG
ATGCGTGTGGCTTTATAGGGCTTTTTTTTTTTTCCAGTTTGTTTTATTACTTTGTTTGGGATGCTTCTTCGCTGGTGCAGTCTACCCAGA
TTGGGTTCCCTTTGCAAAACATCCCCCTTCCTGGAGATGATGATGCCATCGAAGCCCGGGCCAGGGCCTGACCTGGCAGGCACACACCTG
GCCAGTGGCTCTGAGGTCCCCGGGGACCGAGTCCCCTGCGAGGGCAGGCTGCCCGAGGCCACACCTGCCCACCTTCCCTACTCCAGGCCA
CCAGCTGGTGTCAGATTGGGCCACCGGGAGAGAACAGGCCTAGGAGGGAATGGAAGGCTGGCGGGGAGGCTGTCATCCAGAAGCCTCCTC
CCCAGAGGTCTCCAGGAGGAACCTGGCTCAACTGGGGGGCAGTGGTTTACTTTTCCCTTTTTTCTTCCTTTCTTTTGTCCTCTCAGCTGC
CCACAGCCAGAAAGCCAGGACCACCCGAACTGGACAGGGAGCAGGGAGGGAGGAGTGGTCGCACGGAGCGTACCTGATTCAACAGGAAAT
CAGTTATTTTCTAAAACAGCCCCTACCAGAGCCTCCTGAACTCTGTGGGCACCACGTGCTGCTGTGAGCATCTGCCCAGACAGTGACCCG
CCACAGGCCCCGGGCGTCTGTGGAAGGAGTTTTGTAAAGGAAAAAAAAACACACACACACAAACATTTTTTCAATGTAGCAAAATCAAAC
TTAAAAAAAAAAAAGAAGAAAAGAAGAAGATGCCGACAGTGCGGAGTCTAGCCTTTTGTAAACTTCATATTGCACACTAGGACTATAAGC
CATTGCTAGCTCATTTTGAATTTTAACGTGTAATTTTTGTTTTATTTTCTTTCTGTGGGGAAACAATGCTTGATCCACCAATGCTCTTTT
TAATGTTTTATAACTATGTATGTGTATATATATAAATATCAAATAATATGTATGCACATATGTGTGTGTATATATCTATATGTATATACA
TATATAGATATATAGAGATATATAGAGAGGTTTTGAGACAAAAAAAATACAGAACGTGAAACCCGAGCTGAACAGCGTGTGCTCTGATTA
CTTGAATCTGGTCTCCTCGGCACCTGGTTATTAAGAACTGAATATTTTTCCACTTGAATTTAGTGCTATTAGAAATTTAATATATGTGTT

>In-frame_OBSCN_ENST00000570156_chr1_228412435_+_CASZ1_ENST00000344008_chr1_10725628_-_7348nt
TGCCTCCCAGCCTGTGCCCCCAGCCTGCGTGCTGCCCAGAGCCCCCATAGAGAGAGGTCCCCGCCGCCACCCTCATGGATCAGCCACAGT
TCAGCGGGGCGCCCCGCTTTCTCACCCGGCCCAAGGCCTTCGTGGTGTCGGTGGGCAAGGACGCCACCCTCAGCTGCCAGATCGTGGGTA
ATCCCACGCCACAGGTGAGCTGGGAGAAGGACCAGCAGCCGGTGGCGGCCGGCGCGCGCTTCCGTCTGGCCCAGGACGGCGACCTCTACC
GCCTCACTATCCTGGACCTGGCGCTGGGCGACAGTGGGCAATACGTGTGCCGCGCGCGCAATGCCATAGGCGAGGCCTTCGCTGCTGTGG
GCCTGCAGGTGGACGCGGAGGCCGCGTGCGCCGAGCAGGCGCCGCACTTCCTGCTGCGGCCCACGTCCATCCGCGTGCGCGAGGGCTCAG
AGGCCACCTTCCGCTGCCGCGTGGGTGGCTCCCCGAGGCCGGCAGTGAGCTGGTCCAAGGACGGGCGGCGCCTGGGTGAGCCCGACGGCC
CCCGCGTGCGCGTGGAGGAGCTCGGCGAGGCAAGTGCGCTGCGCATTCGGGCGGCGCGGCCGCGCGACGGCGGCACTTACGAGGTCCGCG
CCGAGAACCCGCTGGGCGCTGCCAGCGCCGCCGCGGCGCTAGTGGTGGACTCGGACGCCGCGGACACGGCCAGCCGGCCCGGGACCTCCA
CGGCCGCGCTCCTGGCGCACCTGCAGCGGCGGCGCGAGGCTATGCGCGCCGAGGGCGCCCCCGCCTCACCGCCCAGCACCGGCACGCGCA
CCTGCACGGTGACTGAAGGCAAGCACGCGCGCCTCAGCTGCTACGTGACCGGCGAGCCCAAGCCCGAGACGGTGTGGAAGAAGGACGGCC
AGCTGGTGACCGAGGGCCGGCGCCACGTGGTGTACGAGGACGCGCAGGAGAACTTCGTGCTCAAGATCCTCTTCTGCAAGCAGTCGGACC
GCGGCCTCTACACCTGCACGGCGTCCAACCTCGTGGGCCAGACCTACAGCTCTGTGCTGGTCGTAGTGCGCGAGCCCGCGGTTCCCTTCA
AAAAGCGGCTGCAAGATCTGGAGGTGCGGGAGAAGGAGTCGGCCACGTTCCTATGTGAGGTGCCCCAGCCGTCCACTGAGGCCGCGTGGT
TCAAGGAGGAGACGCGGTTGTGGGCGAGCGCCAAGTACGGCATCGAGGAGGAGGGCACCGAGCGCCGCCTGACCGTGCGCAATGTCTCGG
CCGACGACGACGCGGTGTACATCTGCGAGACGCCAGAGGGCAGCCGCACGGTGGCGGAGCTCGCAGTCCAAGGAAACCTCCTCCGAAAGC
TCCCTCGGAAGACGGCGGTGCGCGTGGGCGACACGGCTATGTTTTGCGTGGAGCTGGCGGTCCCGGTGGGCCCCGTCCACTGGCTGCGGA
ACCAGGAGGAAGTGGTGGCGGGGGGCCGCGTGGCCATCTCCGCGGAGGGCACGCGCCACACACTAACCATCTCCCAGTGCTGCCTGGAGG
ATGTGGGCCAGGTGGCCTTTATGGCTGGCGACTGCCAGACGTCCACCCAGTTCTGCGTGTCGGCCCCCAGGAAGCCTCCCCTGCAACCCC
CTGTGGATCCTGTGGTAAAGGCCAGGATGGAGAGTTCCGTGATTCTCAGCTGGTCCCCACCACCCCATGGGGAACGCCCTGTCACTATCG
ACGGCTACCTGGTAGAGAAGAAGAAGCTTGGCACCTACACCTGGATCAGGTGCCACGAGGCTGAATGGGTGGCTACACCTGAGCTGACCG
TGGCTGATGTGGCGGAGGAGGGGAACTTCCAGTTCCGAGTGTCCGCTCTCAACAGCTTTGGTCAGAGTCCCTACCTCGAGTTCCCGGGGA
CTGTCCACCTGGCCCCCAAGCTGGCCGTGAGGACACCGCTGAAGGCGGTGCAGGCGGTAGAGGGTGGCGAGGTCACTTTCTCCGTGGACC
TCACGGTGGCCTCAGCGGGTGAGTGGTTCCTGGATGGGCAGGCCCTGAAGGCCAGCAGTGTGTATGAGATCCACTGTGATCGCACCCGGC
ACACGCTCACCATCCGGGAGGTGCCCGCCAGCCTGCACGGGGCGCAGCTGAAGTTCGTGGCCAACGGCATTGAGAGCAGCATCCGGATGG
AGGTCCGGGCGGCCCCAGGGCTGACTGCCAACAAGCCGCCAGCCGCAGCTGCCCGGGAGGTGCTGGCTCGGCTGCACGAGGAGGCGCAGC
TGCTGGCTGAGCTGTCAGATCAGGCTGCGGCTGTGACGTGGCTGAAGGATGGTCGCACACTGTCCCCAGGCCCCAAGTATGAGGTGCAGG
CATCGGCCGGGCGGCGGGTGCTCCTTGTGCGAGATGTGGCCCGGGACGATGCAGGCCTCTACGAGTGCGTCAGCCGCGGGGGCCGCATCG
CCTACCAGCTCTCCGTGCAAGGCCTCGCGCGCTTTCTGCACAAGGACATGGCGGGCAGCTGTGTGGATGCCGTGGCTGGGGGCCCGGCGC
AGTTTGAGTGTGAGACCTCCGAAGCCCACGTCCACGTGCACTGGTACAAGGATGGCATGGAGCTGGGCCACTCCGGTGAGCGCTTCTTGC
AGGAGGATGTGGGGACGCGGCACCGGCTGGTGGCAGCCACAGTCACCAGGCAGGATGAAGGCACCTACTCCTGCCGCGTGGGCGAGGACT
CTGTGGACTTCCGGCTCCGCGTCTCTGAGCCCAAGGCGGTGTTTGCCAAGGAGCAGCCGGCGTGCAGGGAGGTGCAGGCTGAGGTGGGGG
CCAGCGCCACGCTGAGCTGTGAGGTGGCCCAGGACCAGATGGAGGTGACGTGGTACAAGGACGGGAAGAAGTTGAGCTCCAGCTCGAAAG
TGCACGTGGAGGCTGTGGGCTGTATGCGGAGGCTGGTGGTGCAGCAGGTGGGCCAGGCAGACTCCGGAGAGTACAGCTGTGAGGCCAGGG
GACAGAGGGTCTCCTTCCGCCTGGACGTTGCAGAGCCCAAGGTGGTGTTTGCTAAGGAGCAGCTGGCACGCAGGAAGCTGCAGGCAGAGG
CAGGAGCCAGTGCCACACTGAGCTGCGAGGTGGCCCAGGCCCAGACGGAGGTGACGTGGTACAAGGATGGGAAGAAGCTGAGCTCCAGCT
CGAAAGTGTGCATGGAGGCCACAGGCTGCACGCGCAGGCTGGTTGTGCAGCAGGCAGGCCAGGCGGATGCCGGGGAGTATAGCTGCGAGG
CTGGGGGCCAGCGGCTCTCCTTCCATCTGGATGTCAAAGCTGAGGGCACCCGGTGCACGGACCCGCCTGCAGGCAAGCCCGCCATGGCGC
CCAAACGCAAGGGTGGCCTGAAGCTGAACGCCATCTGCGCCAAGCTGAGCCGCCAGGTGGTGGTGGAGAAGCGAGCTGACGCCGGCTCCC
ACACGGAGGGCAGCCCATCGCAGCCCCGGGACCAAGAGCGCAGTGGCCCTGAGTCTGGGGCAGCCCGGGCCCCCCGCAGCGAGGAAGACA
AGAGACGGGCAGTGATCGAGAAGTGGGTGAACGGGGAGTACAGCGAGGAGCCGGCACCCACACCCGTGTTGGGGCGGATTGCCCGCGAGG
GCCTGGAGCTGCCTCCCGAGGGTGTCTACATGGTGCAGCCCCAGGGGTGCAGCGATGAGGAAGACCACGCGGAGGAGCCCTCCAAGGACG
GCGGTGCCCTGGAGGAGAAGGATTCGGACGGGGCAGCCTCCAAGGAGGACAGCGGCCCCAGCACCAGGCAGGCTTCAGGAGAGGCCTCCT
CGCTGCGGGACTACGCGGCCTCCACCATGACCGAGTTCCTCGGCATGTTTGGCTATGATGACCAGAACACGCGGGACGAGCTGGCCAGGA
AGATCAGCTTTGAGAAGCTGCACGCGGGCTCCACCCCGGAGGCAGCCACCTCCTCCATGCTGCCCACCTCCGAGGATACCCTCAGCAAGC
GGGCGCGGTTCTCTAAGTATGAGGAGTACATCCGCAAGCTCAAGGCTGGCGAGCAGCTCTCCTGGCCGGCCCCCAGCACCAAGACCGAGG
AGCGGGTGGGCAAGGAGGTGGTGGGCACCCTGCCCGGCCTGCGGCTGCCCAGCAGCACGGCCCACCTGGAGACCAAGGCCACCATCCTGC
CCCTGCCGTCGCACAGCAGTGTCCAGATGCAGAACCTGGTAGCCCGGGCCTCCAAGTACGACTTCTTCATCCAAAAACTGAAGACCGGCG
AGAATCTGCGGCCCCAGAACGGGAGCACCTACAAGAAGCCATCCAAGTACGACCTGGAGAATGTCAAGTACCTGCACCTCTTCAAACCCG
GGGAGGGCAGCCCCGACATGGGCGGGGCCATCGCCTTCAAGACAGGCAAGGTGGGGCGCCCTTCCAAGTACGACGTCCGGGGCATCCAGA
AGCCAGGCCCCGCCAAGGTTCCGCCCACCCCCAGCCTGGCTCCCGCACCCCTCGCCAGCGTGCCCAGTGCCCCCAGCGCCCCCGGGCCAG
GGCCAGAGCCTCCTGCCTCCCTGTCCTTCAACACTCCCGAGTACCTGAAGTCAACCTTCTCCAAAACAGACTCCATCACCACGGGGACCG
TCTCCACTGTCAAGAACGGACTGCCCACAGATAAACCAGCCGTCACTGAAGATGTAAACATTTACCAGAAATATATTGCCAGGTTCTCGG
GCAGCCAGCACTGTGGCCACATCCACTGTGCCTACCAGTACCGCGAGCACTACCACTGCCTTGACCCTGAGTGTAACTACCAGAGGTTCA
CGAGTAAGCAGGACGTGATCCGCCACTACAACATGCACAAGAAGCGCGACAACTCCCTGCAGCACGGCTTCATGCGTTTCAGCCCGCTGG
ACGACTGCAGCGTCTACTACCACGGCTGCCACCTCAATGGGAAGAGCACCCACTATCACTGCATGCAGGTGGGCTGTAACAAGGTGTACA
CGAGCACGTCTGACGTGATGACCCACGAGAACTTCCACAAGAAGAATACCCAGCTCATTAACGACGGCTTCCAGCGCTTCCGAGCCACCG
AAGACTGTGGCACAGCCGACTGCCAGTTCTACGGACAGAAGACCACGCACTTCCACTGCAGGCGCCCCGGCTGCACATTCACTTTCAAGA
ACAAGTGTGACATCGAGAAGCACAAGAGCTACCACATCAAGGACGATGCCTACGCCAAGGACGGCTTCAAGAAGTTCTACAAGTACGAGG
AGTGCAAGTACGAGGGCTGCGTGTACAGCAAGGCTACCAACCACTTCCACTGCATCCGCGCCGGCTGCGGCTTCACCTTCACCTCCACCA
GCCAGATGACCTCTCACAAGCGCAAGCATGAGCGCCGGCACATCCGCTCCTCGGGCGCGCTGGGGCTGCCGCCCTCGCTGCTGGGCGCCA
AGGACACGGAGCACGAGGAGTCCAGCAACGACGACCTTGTTGACTTCTCCGCCCTGAGCAGCAAGAACTCCAGCCTGAGCGCCTCCCCTA
CCAGCCAGCAGTCCTCTGCGTCCCTGGCTGCCGCCACTGCCGCCACCGAGGCTGGGCCCAGTGCCACCAAACCTCCCAACAGCAAGATCT
CGGGGCTGCTGCCCCAGGGCCTGCCTGGCTCAATCCCCCTGGCCCTGGCCCTCTCCAACTCGGGCCTGCCCACCCCCACGCCCTACTTCC
CCATACTGGCTGGCCGTGGGAGCACCTCCCTGCCTGTGGGCACCCCCAGCCTCCTGGGTGCCGTGTCGTCTGGGTCAGCAGCCTCAGCCA
CCCCTGACACACCCACGCTGGTCGCCTCGGGAGCTGGAGACTCAGCCCCCGTGGCTGCCGCCTCTGTCCCGGCACCACCCGCCTCCATCA
TGGAGAGGATCTCTGCAAGCAAGGGCCTCATCTCGCCCATGATGGCCAGGCTGGCTGCAGCTGCCCTCAAGCCCTCTGCCACCTTTGACC
CAGGAAGCGGGCAGCAGGTCACCCCAGCCAGGTTCCCCCCGGCCCAAGTGAAGCCGGAACCCGGTGAGAGCACCGGCGCCCCAGGCCCCC
ACGAAGCCTCCCAGGACCGCAGTCTAGACCTGACTGTGAAGGAGCCCAGCAACGAATCAAATGGCCACGCAGTCCCGGCAAATTCATCTC
TTTTATCCTCGCTTATGAATAAGATGTCTCAGGGCAACCCTGGCCTGGGCAGCCTGCTGAACATCAAGGCGGAAGCGGAGGGGAGCCCCG
CTGCGGAGCCCTCGCCCTTCCTAGGCAAGGCCGTGAAGGCGCTGGTTCAGGAGAAGTTGGCAGAGCCCTGGAAGGTGTACCTGCGCAGGT
TTGGTACAAAGGACTTCTGTGACGGCCAGTGTGACTTCCTCCACAAGGCCCACTTCCACTGCGTGGTGGAGGAATGCGGCGCGCTCTTCA
GCACCTTGGACGGGGCCATCAAGCACGCAAACTTCCACTTCCGGACAGAGGGAGGAGCAGCAAAAGGAAACACAGAGGCTGCCTTTCCGG
CCTCGGCCGCCGAGACCAAACCTCCCATGGCCCCCTCGTCCCCTCCGGTCCCTCCTGTCACCACGGCCACGGTGTCCTCTCTGGAGGGGC
CCGCTCCCAGCCCGGCCTCCGTGCCCTCCACCCCCACCCTGCTCGCCTGGAAGCAGCTGGCTTCCACCATACCCCAGATGCCTCAGATCC
CAGCGTCAGTGCCTCACCTGCCCGCCTCGCCCTTGGCAACGACTTCTCTAGAGAACGCCAAGCCCCAGGTCAAACCCGGATTCCTCCAGT
TCCAGGAGAAGTGAGTCCCTCGATGAGCCGGGAGTCCCGCGTTCCCCTCGCGTCTCGGGAGTAGGTGCTAGCAAGGGCGCTAGGAGGCCC
TGTTCCTCACTGCGGATGGTGCTGCTGTCCCCAGCCTCTCTGGGGCATGGCCATCGGGTGATGTCCTTCTAGCCAAAGATGCTGCTGCTC
CTACCTCACTGCCTGTCCCAGAGCAGGCCAGCCCGCGTGGGCCGATGGTGGCGGCAGTGGCTACTGCTCCTGCAGGGCATGTGGTGATCC
TGCCAGGGCCAGGTGGGGTGGACTGGGCGTGGTGGTCCTCAGAGGACAACTCCCAGCCTGACAAGGAGGGCTGCGTCTCCCTCCGAGCCT
CCGTATTGGCCTCCTCTGTGGCTCACACCCATGGCTGAATCTCTGCAGGGCACGTGAAGTCACGGGTAGGGGCCAGGCCCCTCCAGGCCG
TCACTGGCCTGCACAGTGGTCTGAGCTCTTGGGTGGAAGGGACCCTCCTCACTGGATGGTGGTGGCTCCTTGCAGGGAGAACGGTGACTT

>In-frame_OBSCN_ENST00000422127_chr1_228412435_+_CASZ1_ENST00000377022_chr1_10725628_-_10575nt
GCTGCCCAGAGCCCCCATAGAGAGAGGTCCCCGCCGCCACCCTCATGGATCAGCCACAGTTCAGCGGGGCGCCCCGCTTTCTCACCCGGC
CCAAGGCCTTCGTGGTGTCGGTGGGCAAGGACGCCACCCTCAGCTGCCAGATCGTGGGTAATCCCACGCCACAGGTGAGCTGGGAGAAGG
ACCAGCAGCCGGTGGCGGCCGGCGCGCGCTTCCGTCTGGCCCAGGACGGCGACCTCTACCGCCTCACTATCCTGGACCTGGCGCTGGGCG
ACAGTGGGCAATACGTGTGCCGCGCGCGCAATGCCATAGGCGAGGCCTTCGCTGCTGTGGGCCTGCAGGTGGACGCGGAGGCCGCGTGCG
CCGAGCAGGCGCCGCACTTCCTGCTGCGGCCCACGTCCATCCGCGTGCGCGAGGGCTCAGAGGCCACCTTCCGCTGCCGCGTGGGTGGCT
CCCCGAGGCCGGCAGTGAGCTGGTCCAAGGACGGGCGGCGCCTGGGTGAGCCCGACGGCCCCCGCGTGCGCGTGGAGGAGCTCGGCGAGG
CAAGTGCGCTGCGCATTCGGGCGGCGCGGCCGCGCGACGGCGGCACTTACGAGGTCCGCGCCGAGAACCCGCTGGGCGCTGCCAGCGCCG
CCGCGGCGCTAGTGGTGGACTCGGACGCCGCGGACACGGCCAGCCGGCCCGGGACCTCCACGGCCGCGCTCCTGGCGCACCTGCAGCGGC
GGCGCGAGGCTATGCGCGCCGAGGGCGCCCCCGCCTCACCGCCCAGCACCGGCACGCGCACCTGCACGGTGACTGAAGGCAAGCACGCGC
GCCTCAGCTGCTACGTGACCGGCGAGCCCAAGCCCGAGACGGTGTGGAAGAAGGACGGCCAGCTGGTGACCGAGGGCCGGCGCCACGTGG
TGTACGAGGACGCGCAGGAGAACTTCGTGCTCAAGATCCTCTTCTGCAAGCAGTCGGACCGCGGCCTCTACACCTGCACGGCGTCCAACC
TCGTGGGCCAGACCTACAGCTCTGTGCTGGTCGTAGTGCGCGAGCCCGCGGTTCCCTTCAAAAAGCGGCTGCAAGATCTGGAGGTGCGGG
AGAAGGAGTCGGCCACGTTCCTATGTGAGGTGCCCCAGCCGTCCACTGAGGCCGCGTGGTTCAAGGAGGAGACGCGGTTGTGGGCGAGCG
CCAAGTACGGCATCGAGGAGGAGGGCACCGAGCGCCGCCTGACCGTGCGCAATGTCTCGGCCGACGACGACGCGGTGTACATCTGCGAGA
CGCCAGAGGGCAGCCGCACGGTGGCGGAGCTCGCAGTCCAAGGAAACCTCCTCCGAAAGCTCCCTCGGAAGACGGCGGTGCGCGTGGGCG
ACACGGCTATGTTTTGCGTGGAGCTGGCGGTCCCGGTGGGCCCCGTCCACTGGCTGCGGAACCAGGAGGAAGTGGTGGCGGGGGGCCGCG
TGGCCATCTCCGCGGAGGGCACGCGCCACACACTAACCATCTCCCAGTGCTGCCTGGAGGATGTGGGCCAGGTGGCCTTTATGGCTGGCG
ACTGCCAGACGTCCACCCAGTTCTGCGTGTCGGCCCCCAGGAAGCCTCCCCTGCAACCCCCTGTGGATCCTGTGGTAAAGGCCAGGATGG
AGAGTTCCGTGATTCTCAGCTGGTCCCCACCACCCCATGGGGAACGCCCTGTCACTATCGACGGCTACCTGGTAGAGAAGAAGAAGCTTG
GCACCTACACCTGGATCAGGTGCCACGAGGCTGAATGGGTGGCTACACCTGAGCTGACCGTGGCTGATGTGGCGGAGGAGGGGAACTTCC
AGTTCCGAGTGTCCGCTCTCAACAGCTTTGGTCAGAGTCCCTACCTCGAGTTCCCGGGGACTGTCCACCTGGCCCCCAAGCTGGCCGTGA
GGACACCGCTGAAGGCGGTGCAGGCGGTAGAGGGTGGCGAGGTCACTTTCTCCGTGGACCTCACGGTGGCCTCAGCGGGTGAGTGGTTCC
TGGATGGGCAGGCCCTGAAGGCCAGCAGTGTGTATGAGATCCACTGTGATCGCACCCGGCACACGCTCACCATCCGGGAGGTGCCCGCCA
GCCTGCACGGGGCGCAGCTGAAGTTCGTGGCCAACGGCATTGAGAGCAGCATCCGGATGGAGGTCCGGGCGGCCCCAGGGCTGACTGCCA
ACAAGCCGCCAGCCGCAGCTGCCCGGGAGGTGCTGGCTCGGCTGCACGAGGAGGCGCAGCTGCTGGCTGAGCTGTCAGATCAGGCTGCGG
CTGTGACGTGGCTGAAGGATGGTCGCACACTGTCCCCAGGCCCCAAGTATGAGGTGCAGGCATCGGCCGGGCGGCGGGTGCTCCTTGTGC
GAGATGTGGCCCGGGACGATGCAGGCCTCTACGAGTGCGTCAGCCGCGGGGGCCGCATCGCCTACCAGCTCTCCGTGCAAGGCCTCGCGC
GCTTTCTGCACAAGGACATGGCGGGCAGCTGTGTGGATGCCGTGGCTGGGGGCCCGGCGCAGTTTGAGTGTGAGACCTCCGAAGCCCACG
TCCACGTGCACTGGTACAAGGATGGCATGGAGCTGGGCCACTCCGGTGAGCGCTTCTTGCAGGAGGATGTGGGGACGCGGCACCGGCTGG
TGGCAGCCACAGTCACCAGGCAGGATGAAGGCACCTACTCCTGCCGCGTGGGCGAGGACTCTGTGGACTTCCGGCTCCGCGTCTCTGAGC
CCAAGGTGGTGTTTGCTAAGGAGCAGCTGGCACGCAGGAAGCTGCAGGCAGAGGCAGGAGCCAGTGCCACACTGAGCTGCGAGGTGGCCC
AGGCCCAGACGGAGGTGACGTGGTACAAGGATGGGAAGAAGCTGAGCTCCAGCTCGAAAGTGTGCATGGAGGCCACAGGCTGCACGCGCA
GGCTGGTTGTGCAGCAGGCAGGCCAGGCGGATGCCGGGGAGTATAGCTGCGAGGCTGGGGGCCAGCGGCTCTCCTTCCATCTGGATGTCA
AAGCTGAGGGCACCCGGTGCACGGACCCGCCTGCAGGCAAGCCCGCCATGGCGCCCAAACGCAAGGGTGGCCTGAAGCTGAACGCCATCT
GCGCCAAGCTGAGCCGCCAGGTGGTGGTGGAGAAGCGAGCTGACGCCGGCTCCCACACGGAGGGCAGCCCATCGCAGCCCCGGGACCAAG
AGCGCAGTGGCCCTGAGTCTGGGGCAGCCCGGGCCCCCCGCAGCGAGGAAGACAAGAGACGGGCAGTGATCGAGAAGTGGGTGAACGGGG
AGTACAGCGAGGAGCCGGCACCCACACCCGTGTTGGGGCGGATTGCCCGCGAGGGCCTGGAGCTGCCTCCCGAGGGTGTCTACATGGTGC
AGCCCCAGGGGTGCAGCGATGAGGAAGACCACGCGGAGGAGCCCTCCAAGGACGGCGGTGCCCTGGAGGAGAAGGATTCGGACGGGGCAG
CCTCCAAGGAGGACAGCGGCCCCAGCACCAGGCAGGCTTCAGGAGAGGCCTCCTCGCTGCGGGACTACGCGGCCTCCACCATGACCGAGT
TCCTCGGCATGTTTGGCTATGATGACCAGAACACGCGGGACGAGCTGGCCAGGAAGATCAGCTTTGAGAAGCTGCACGCGGGCTCCACCC
CGGAGGCAGCCACCTCCTCCATGCTGCCCACCTCCGAGGATACCCTCAGCAAGCGGGCGCGGTTCTCTAAGTATGAGGAGTACATCCGCA
AGCTCAAGGCTGGCGAGCAGCTCTCCTGGCCGGCCCCCAGCACCAAGACCGAGGAGCGGGTGGGCAAGGAGGTGGTGGGCACCCTGCCCG
GCCTGCGGCTGCCCAGCAGCACGGCCCACCTGGAGACCAAGGCCACCATCCTGCCCCTGCCGTCGCACAGCAGTGTCCAGATGCAGAACC
TGGTAGCCCGGGCCTCCAAGTACGACTTCTTCATCCAAAAACTGAAGACCGGCGAGAATCTGCGGCCCCAGAACGGGAGCACCTACAAGA
AGCCATCCAAGTACGACCTGGAGAATGTCAAGTACCTGCACCTCTTCAAACCCGGGGAGGGCAGCCCCGACATGGGCGGGGCCATCGCCT
TCAAGACAGGCAAGGTGGGGCGCCCTTCCAAGTACGACGTCCGGGGCATCCAGAAGCCAGGCCCCGCCAAGGTTCCGCCCACCCCCAGCC
TGGCTCCCGCACCCCTCGCCAGCGTGCCCAGTGCCCCCAGCGCCCCCGGGCCAGGGCCAGAGCCTCCTGCCTCCCTGTCCTTCAACACTC
CCGAGTACCTGAAGTCAACCTTCTCCAAAACAGACTCCATCACCACGGGGACCGTCTCCACTGTCAAGAACGGACTGCCCACAGATAAAC
CAGCCGTCACTGAAGATGTAAACATTTACCAGAAATATATTGCCAGGTTCTCGGGCAGCCAGCACTGTGGCCACATCCACTGTGCCTACC
AGTACCGCGAGCACTACCACTGCCTTGACCCTGAGTGTAACTACCAGAGGTTCACGAGTAAGCAGGACGTGATCCGCCACTACAACATGC
ACAAGAAGCGCGACAACTCCCTGCAGCACGGCTTCATGCGTTTCAGCCCGCTGGACGACTGCAGCGTCTACTACCACGGCTGCCACCTCA
ATGGGAAGAGCACCCACTATCACTGCATGCAGGTGGGCTGTAACAAGGTGTACACGAGCACGTCTGACGTGATGACCCACGAGAACTTCC
ACAAGAAGAATACCCAGCTCATTAACGACGGCTTCCAGCGCTTCCGAGCCACCGAAGACTGTGGCACAGCCGACTGCCAGTTCTACGGAC
AGAAGACCACGCACTTCCACTGCAGGCGCCCCGGCTGCACATTCACTTTCAAGAACAAGTGTGACATCGAGAAGCACAAGAGCTACCACA
TCAAGGACGATGCCTACGCCAAGGACGGCTTCAAGAAGTTCTACAAGTACGAGGAGTGCAAGTACGAGGGCTGCGTGTACAGCAAGGCTA
CCAACCACTTCCACTGCATCCGCGCCGGCTGCGGCTTCACCTTCACCTCCACCAGCCAGATGACCTCTCACAAGCGCAAGCATGAGCGCC
GGCACATCCGCTCCTCGGGCGCGCTGGGGCTGCCGCCCTCGCTGCTGGGCGCCAAGGACACGGAGCACGAGGAGTCCAGCAACGACGACC
TTGTTGACTTCTCCGCCCTGAGCAGCAAGAACTCCAGCCTGAGCGCCTCCCCTACCAGCCAGCAGTCCTCTGCGTCCCTGGCTGCCGCCA
CTGCCGCCACCGAGGCTGGGCCCAGTGCCACCAAACCTCCCAACAGCAAGATCTCGGGGCTGCTGCCCCAGGGCCTGCCTGGCTCAATCC
CCCTGGCCCTGGCCCTCTCCAACTCGGGCCTGCCCACCCCCACGCCCTACTTCCCCATACTGGCTGGCCGTGGGAGCACCTCCCTGCCTG
TGGGCACCCCCAGCCTCCTGGGTGCCGTGTCGTCTGGGTCAGCAGCCTCAGCCACCCCTGACACACCCACGCTGGTCGCCTCGGGAGCTG
GAGACTCAGCCCCCGTGGCTGCCGCCTCTGTCCCGGCACCACCCGCCTCCATCATGGAGAGGATCTCTGCAAGCAAGGGCCTCATCTCGC
CCATGATGGCCAGGCTGGCTGCAGCTGCCCTCAAGCCCTCTGCCACCTTTGACCCAGGAAGCGGGCAGCAGGTCACCCCAGCCAGGTTCC
CCCCGGCCCAAGTGAAGCCGGAACCCGGTGAGAGCACCGGCGCCCCAGGCCCCCACGAAGCCTCCCAGGACCGCAGTCTAGACCTGACTG
TGAAGGAGCCCAGCAACGAATCAAATGGCCACGCAGTCCCGGCAAATTCATCTCTTTTATCCTCGCTTATGAATAAGATGTCTCAGGGCA
ACCCTGGCCTGGGCAGCCTGCTGAACATCAAGGCGGAAGCGGAGGGGAGCCCCGCTGCGGAGCCCTCGCCCTTCCTAGGCAAGGCCGTGA
AGGCGCTGGTTCAGGAGAAGTTGGCAGAGCCCTGGAAGGTGTACCTGCGCAGGTTTGGTACAAAGGACTTCTGTGACGGCCAGTGTGACT
TCCTCCACAAGGCCCACTTCCACTGCGTGGTGGAGGAATGCGGCGCGCTCTTCAGCACCTTGGACGGGGCCATCAAGCACGCAAACTTCC
ACTTCCGGACAGAGGGAGGAGCAGCAAAAGGAAACACAGAGGCTGCCTTTCCGGCCTCGGCCGCCGAGACCAAACCTCCCATGGCCCCCT
CGTCCCCTCCGGTCCCTCCTGTCACCACGGCCACGGTGTCCTCTCTGGAGGGGCCCGCTCCCAGCCCGGCCTCCGTGCCCTCCACCCCCA
CCCTGCTCGCCTGGAAGCAGCTGGCTTCCACCATACCCCAGATGCCTCAGATCCCAGCGTCAGTGCCTCACCTGCCCGCCTCGCCCTTGG
CAACGACTTCTCTAGAGAACGCCAAGCCCCAGGTCAAACCCGGATTCCTCCAGTTCCAGGAGAACGATCCTTGCCTCGCCACGGACTGCA
AGTACGCCAACAAGTTCCACTTCCACTGTCTCTTTGGGAACTGCAAGTACGTCTGCAAAACGTCTGGCAAGGCCGAATCCCACTGCCTGG
ACCACATCAACCCCAACAACAACCTGGTGAACGTGCGAGACCAGTTTGCATACTACTCTCTGCAGTGTCTCTGTCCCAACCAGCACTGCG
AGTTCCGAATGCGTGGGCACTACCACTGCCTCCGCACCGGCTGCTATTTTGTGACCAACATCACCACCAAGCTCCCCTGGCACATCAAGA
AGCATGAGAAGGCGGAGCGGCGGGCAGCCAATGGCTTCAAATACTTCACCAAGCGCGAGGAGTGTGGCAGGCTAGGTTGCAAGTACAACC
AGGTGAACAGCCACTTCCACTGCATCCGGGAGGGCTGCCAGTTCTCCTTCCTCCTCAAGCACCAGATGACCTCCCACGCGCGGAAGCACA
TGCGGAGGATGCTGGGGAAGAACTTCGACCGCGTGCCCCCCTCCCAGGGCCCCCCAGGCCTGATGGATGCTGAGACAGATGAGTGCATGG
ACTACACTGGCTGCAGCCCAGGCGCCATGTCCTCTGAGTCATCCACCATGGACCGGAGCTGCTCCAGCACCCCCGTGGGTAACGAGAGCA
CCGCGGCAGGGAACACCATCTCTATGCCGACAGCCTCGGGGGCCAAAAAGCGCTTCTGGATCATCGAGGACATGTCGCCCTTCGGCAAGC
GGCGGAAGACGGCGTCCTCCCGGAAGATGCTGGACGAGGGCATGATGCTGGAGGGCTTCCGGCGCTTCGACCTTTACGAGGACTGCAAGG
ACGCAGCTTGTCAGTTCTCGCTCAAGGTCACCCACTACCACTGCACGCGCGAGAACTGCGGCTACAAGTTCTGCGGGCGCACGCACATGT
ACAAGCACGCGCAGCACCACGACCGCGTGGACAACCTGGTGCTGGACGACTTCAAGCGCTTCAAGGCCTCACTCAGCTGCCACTTCGCCG
ACTGCCCCTTCTCGGGCACCAGCACGCACTTCCACTGCCTGCGCTGCCGCTTCCGCTGCACCGACAGCACCAAGGTCACGGCGCATCGCA
AGCACCACGGCAAACAGGACGTGATCAGCGCCGCGGGCTTCTGCCAGTTCAGCTCCAGCGCCGACTGCGCCGTGCCCGACTGCAAGTACA
AGCTCAAGTGCTCGCACTTCCACTGCACCTTCCCGGGCTGCCGCCACACGGTGGTGGGCATGTCGCAGATGGACTCGCACAAGCGCAAGC
ACGAGAAGCAGGAGCGCGGCGAGCCCGCGGCAGAGGGCCCCGCGCCCGGGCCTCCCATCAGTCTGGACGGCTCCCTGTCGCTGGGCGCCG
AGCCGGGCTCGCTGCTCTTCCTGCAGTCGGCGGCCGCCGGCCTGGGCCTGGCGCTGGGCGACGCGGGCGACCCCGGCCCGCCCGACGCCG
CCGCCCCCGGGCCGCGCGAGGGCGCCGCCGCCGCCGCCGCCGCAGCTGGGGAGTCCTCGCAGGAGGACGAGGAGGAGGAGCTGGAGCTGC
CGGAGGAGGAGGCCGAAGACGACGAGGACGAGGACGACGACGAGGACGACGACGACGAGGACGACGACGAGGACGACGACGACGAGGACC
TGCGCACCGACTCGGAGGAGTCGCTGCCCGAGGCGGCGGCGGAGGCGGCGGGCGCGGGCGCGCGGACCCCGGCCTTGGCGGCGCTGGCGG
CCCTGGGCGCCCCCGGCCCCGCGCCCACTGCAGCCTCCTCGCCCTAGCGGCGCCCGCGGGTGGCCCTGGCGGCGGCCTCGGCCTCGGCCT
CGGGAGCGGCGCCGCCCCGCGCGAAGCGGCCCCTGGGCAGAGCCCCGCGCCCCGCCGGTGCTTCCGGACCCCGAGTCCGTCTCAGGACAG
AGGCGGGGACCCCTCTGGTGCTCCGCGGCCGAGGACACAGGCGGCGGCGGTGGCCCTGCTCTAGGGAGGCCGGGTCTCTTCAGGGAAACA
GAAGGTGCTCTTGTCCCGGGGTAGGGAACCTAGGAGCAGGGGTCCCGGGCGAATGCGGCGCAGCTCCCGGCCGCTGCCCCGGCGCCCCTC
CCCGCGGCCGATTCGGCCCCGCGACCATTGCTCAGGACTGGGACGGGCGCTGGGGGCCACCGGGACCCCCACCGCGCGCCACCAGGGCGG
GGTGGCTCCTGGAGCCGCTGGCGGGGCCTCCCTCATGCAGCTAGGATCCTCCCCCCTGCCCAGGGGGAGACGGGCAGAAGGCAGTCAGCA
CGGGTGACACTACAGGGACCGTGGAGGAAGCCTCACGGGAGTAGCAGCCGCGGAGCTCCAGCTCAGCCCCACCCCAGGGCCCGGCTGCTC
CCCCAGGCCTGGGTCGGGTCTGTTTGGCGACTCCCTGGCCCCAGCCTCCGCCCCAGGGAAACCGAGGCTGCGTCCAAAACCCAGAGTAGC
CCGCTGGGGGCCGGGGCGGGGTCTCGGCCACCCTGGTGGTGCAAACAGGAAGGATGCGCCTGGTTTTGGCTTTAATGTTCAAAATGGAAA
AAAATACAAGAAAGTTGTACAGTATTTTTCCTGTAAAGGTTATTATTCTACATAGAACAAAAAGGAAGAAAGCAGGCGTGGTGAGAGTGC
AGACCCGCCTGGGCCCGGCCTGAGGTTGGAGGCTCAGTCCCGTTTATCCTGTGGGATTTGGTCCAGGGTTTTTGTAGAGGCCTTAACTGT
TTGAGGCTGTCTGTCTTCACAATAGCACTGATGGGAGCTGCGTGATTCCAACTCTTAACTTGAATTTTGTAGAGACAAGAAAAAAGGACT
ATTACTGTTGATCCAAGTTTGTAGTTAATTTAACATTTGAGTTCTCTCTTGGTGATGCGTGTGGCTTTATAGGGCTTTTTTTTTTTTCCA
GTTTGTTTTATTACTTTGTTTGGGATGCTTCTTCGCTGGTGCAGTCTACCCAGATTGGGTTCCCTTTGCAAAACATCCCCCTTCCTGGAG
ATGATGATGCCATCGAAGCCCGGGCCAGGGCCTGACCTGGCAGGCACACACCTGGCCAGTGGCTCTGAGGTCCCCGGGGACCGAGTCCCC
TGCGAGGGCAGGCTGCCCGAGGCCACACCTGCCCACCTTCCCTACTCCAGGCCACCAGCTGGTGTCAGATTGGGCCACCGGGAGAGAACA
GGCCTAGGAGGGAATGGAAGGCTGGCGGGGAGGCTGTCATCCAGAAGCCTCCTCCCCAGAGGTCTCCAGGAGGAACCTGGCTCAACTGGG
GGGCAGTGGTTTACTTTTCCCTTTTTTCTTCCTTTCTTTTGTCCTCTCAGCTGCCCACAGCCAGAAAGCCAGGACCACCCGAACTGGACA
GGGAGCAGGGAGGGAGGAGTGGTCGCACGGAGCGTACCTGATTCAACAGGAAATCAGTTATTTTCTAAAACAGCCCCTACCAGAGCCTCC
TGAACTCTGTGGGCACCACGTGCTGCTGTGAGCATCTGCCCAGACAGTGACCCGCCACAGGCCCCGGGCGTCTGTGGAAGGAGTTTTGTA
AAGGAAAAAAAAACACACACACACAAACATTTTTTCAATGTAGCAAAATCAAACTTAAAAAAAAAAAAGAAGAAAAGAAGAAGATGCCGA
CAGTGCGGAGTCTAGCCTTTTGTAAACTTCATATTGCACACTAGGACTATAAGCCATTGCTAGCTCATTTTGAATTTTAACGTGTAATTT
TTGTTTTATTTTCTTTCTGTGGGGAAACAATGCTTGATCCACCAATGCTCTTTTTAATGTTTTATAACTATGTATGTGTATATATATAAA
TATCAAATAATATGTATGCACATATGTGTGTGTATATATCTATATGTATATACATATATAGATATATAGAGATATATAGAGAGGTTTTGA
GACAAAAAAAATACAGAACGTGAAACCCGAGCTGAACAGCGTGTGCTCTGATTACTTGAATCTGGTCTCCTCGGCACCTGGTTATTAAGA
ACTGAATATTTTTCCACTTGAATTTAGTGCTATTAGAAATTTAATATATGTGTTTTATTTATTTGATTTTTTTTTTTTTTTTTGCATGAC

>In-frame_OBSCN_ENST00000422127_chr1_228412435_+_CASZ1_ENST00000344008_chr1_10725628_-_7042nt
GCTGCCCAGAGCCCCCATAGAGAGAGGTCCCCGCCGCCACCCTCATGGATCAGCCACAGTTCAGCGGGGCGCCCCGCTTTCTCACCCGGC
CCAAGGCCTTCGTGGTGTCGGTGGGCAAGGACGCCACCCTCAGCTGCCAGATCGTGGGTAATCCCACGCCACAGGTGAGCTGGGAGAAGG
ACCAGCAGCCGGTGGCGGCCGGCGCGCGCTTCCGTCTGGCCCAGGACGGCGACCTCTACCGCCTCACTATCCTGGACCTGGCGCTGGGCG
ACAGTGGGCAATACGTGTGCCGCGCGCGCAATGCCATAGGCGAGGCCTTCGCTGCTGTGGGCCTGCAGGTGGACGCGGAGGCCGCGTGCG
CCGAGCAGGCGCCGCACTTCCTGCTGCGGCCCACGTCCATCCGCGTGCGCGAGGGCTCAGAGGCCACCTTCCGCTGCCGCGTGGGTGGCT
CCCCGAGGCCGGCAGTGAGCTGGTCCAAGGACGGGCGGCGCCTGGGTGAGCCCGACGGCCCCCGCGTGCGCGTGGAGGAGCTCGGCGAGG
CAAGTGCGCTGCGCATTCGGGCGGCGCGGCCGCGCGACGGCGGCACTTACGAGGTCCGCGCCGAGAACCCGCTGGGCGCTGCCAGCGCCG
CCGCGGCGCTAGTGGTGGACTCGGACGCCGCGGACACGGCCAGCCGGCCCGGGACCTCCACGGCCGCGCTCCTGGCGCACCTGCAGCGGC
GGCGCGAGGCTATGCGCGCCGAGGGCGCCCCCGCCTCACCGCCCAGCACCGGCACGCGCACCTGCACGGTGACTGAAGGCAAGCACGCGC
GCCTCAGCTGCTACGTGACCGGCGAGCCCAAGCCCGAGACGGTGTGGAAGAAGGACGGCCAGCTGGTGACCGAGGGCCGGCGCCACGTGG
TGTACGAGGACGCGCAGGAGAACTTCGTGCTCAAGATCCTCTTCTGCAAGCAGTCGGACCGCGGCCTCTACACCTGCACGGCGTCCAACC
TCGTGGGCCAGACCTACAGCTCTGTGCTGGTCGTAGTGCGCGAGCCCGCGGTTCCCTTCAAAAAGCGGCTGCAAGATCTGGAGGTGCGGG
AGAAGGAGTCGGCCACGTTCCTATGTGAGGTGCCCCAGCCGTCCACTGAGGCCGCGTGGTTCAAGGAGGAGACGCGGTTGTGGGCGAGCG
CCAAGTACGGCATCGAGGAGGAGGGCACCGAGCGCCGCCTGACCGTGCGCAATGTCTCGGCCGACGACGACGCGGTGTACATCTGCGAGA
CGCCAGAGGGCAGCCGCACGGTGGCGGAGCTCGCAGTCCAAGGAAACCTCCTCCGAAAGCTCCCTCGGAAGACGGCGGTGCGCGTGGGCG
ACACGGCTATGTTTTGCGTGGAGCTGGCGGTCCCGGTGGGCCCCGTCCACTGGCTGCGGAACCAGGAGGAAGTGGTGGCGGGGGGCCGCG
TGGCCATCTCCGCGGAGGGCACGCGCCACACACTAACCATCTCCCAGTGCTGCCTGGAGGATGTGGGCCAGGTGGCCTTTATGGCTGGCG
ACTGCCAGACGTCCACCCAGTTCTGCGTGTCGGCCCCCAGGAAGCCTCCCCTGCAACCCCCTGTGGATCCTGTGGTAAAGGCCAGGATGG
AGAGTTCCGTGATTCTCAGCTGGTCCCCACCACCCCATGGGGAACGCCCTGTCACTATCGACGGCTACCTGGTAGAGAAGAAGAAGCTTG
GCACCTACACCTGGATCAGGTGCCACGAGGCTGAATGGGTGGCTACACCTGAGCTGACCGTGGCTGATGTGGCGGAGGAGGGGAACTTCC
AGTTCCGAGTGTCCGCTCTCAACAGCTTTGGTCAGAGTCCCTACCTCGAGTTCCCGGGGACTGTCCACCTGGCCCCCAAGCTGGCCGTGA
GGACACCGCTGAAGGCGGTGCAGGCGGTAGAGGGTGGCGAGGTCACTTTCTCCGTGGACCTCACGGTGGCCTCAGCGGGTGAGTGGTTCC
TGGATGGGCAGGCCCTGAAGGCCAGCAGTGTGTATGAGATCCACTGTGATCGCACCCGGCACACGCTCACCATCCGGGAGGTGCCCGCCA
GCCTGCACGGGGCGCAGCTGAAGTTCGTGGCCAACGGCATTGAGAGCAGCATCCGGATGGAGGTCCGGGCGGCCCCAGGGCTGACTGCCA
ACAAGCCGCCAGCCGCAGCTGCCCGGGAGGTGCTGGCTCGGCTGCACGAGGAGGCGCAGCTGCTGGCTGAGCTGTCAGATCAGGCTGCGG
CTGTGACGTGGCTGAAGGATGGTCGCACACTGTCCCCAGGCCCCAAGTATGAGGTGCAGGCATCGGCCGGGCGGCGGGTGCTCCTTGTGC
GAGATGTGGCCCGGGACGATGCAGGCCTCTACGAGTGCGTCAGCCGCGGGGGCCGCATCGCCTACCAGCTCTCCGTGCAAGGCCTCGCGC
GCTTTCTGCACAAGGACATGGCGGGCAGCTGTGTGGATGCCGTGGCTGGGGGCCCGGCGCAGTTTGAGTGTGAGACCTCCGAAGCCCACG
TCCACGTGCACTGGTACAAGGATGGCATGGAGCTGGGCCACTCCGGTGAGCGCTTCTTGCAGGAGGATGTGGGGACGCGGCACCGGCTGG
TGGCAGCCACAGTCACCAGGCAGGATGAAGGCACCTACTCCTGCCGCGTGGGCGAGGACTCTGTGGACTTCCGGCTCCGCGTCTCTGAGC
CCAAGGTGGTGTTTGCTAAGGAGCAGCTGGCACGCAGGAAGCTGCAGGCAGAGGCAGGAGCCAGTGCCACACTGAGCTGCGAGGTGGCCC
AGGCCCAGACGGAGGTGACGTGGTACAAGGATGGGAAGAAGCTGAGCTCCAGCTCGAAAGTGTGCATGGAGGCCACAGGCTGCACGCGCA
GGCTGGTTGTGCAGCAGGCAGGCCAGGCGGATGCCGGGGAGTATAGCTGCGAGGCTGGGGGCCAGCGGCTCTCCTTCCATCTGGATGTCA
AAGCTGAGGGCACCCGGTGCACGGACCCGCCTGCAGGCAAGCCCGCCATGGCGCCCAAACGCAAGGGTGGCCTGAAGCTGAACGCCATCT
GCGCCAAGCTGAGCCGCCAGGTGGTGGTGGAGAAGCGAGCTGACGCCGGCTCCCACACGGAGGGCAGCCCATCGCAGCCCCGGGACCAAG
AGCGCAGTGGCCCTGAGTCTGGGGCAGCCCGGGCCCCCCGCAGCGAGGAAGACAAGAGACGGGCAGTGATCGAGAAGTGGGTGAACGGGG
AGTACAGCGAGGAGCCGGCACCCACACCCGTGTTGGGGCGGATTGCCCGCGAGGGCCTGGAGCTGCCTCCCGAGGGTGTCTACATGGTGC
AGCCCCAGGGGTGCAGCGATGAGGAAGACCACGCGGAGGAGCCCTCCAAGGACGGCGGTGCCCTGGAGGAGAAGGATTCGGACGGGGCAG
CCTCCAAGGAGGACAGCGGCCCCAGCACCAGGCAGGCTTCAGGAGAGGCCTCCTCGCTGCGGGACTACGCGGCCTCCACCATGACCGAGT
TCCTCGGCATGTTTGGCTATGATGACCAGAACACGCGGGACGAGCTGGCCAGGAAGATCAGCTTTGAGAAGCTGCACGCGGGCTCCACCC
CGGAGGCAGCCACCTCCTCCATGCTGCCCACCTCCGAGGATACCCTCAGCAAGCGGGCGCGGTTCTCTAAGTATGAGGAGTACATCCGCA
AGCTCAAGGCTGGCGAGCAGCTCTCCTGGCCGGCCCCCAGCACCAAGACCGAGGAGCGGGTGGGCAAGGAGGTGGTGGGCACCCTGCCCG
GCCTGCGGCTGCCCAGCAGCACGGCCCACCTGGAGACCAAGGCCACCATCCTGCCCCTGCCGTCGCACAGCAGTGTCCAGATGCAGAACC
TGGTAGCCCGGGCCTCCAAGTACGACTTCTTCATCCAAAAACTGAAGACCGGCGAGAATCTGCGGCCCCAGAACGGGAGCACCTACAAGA
AGCCATCCAAGTACGACCTGGAGAATGTCAAGTACCTGCACCTCTTCAAACCCGGGGAGGGCAGCCCCGACATGGGCGGGGCCATCGCCT
TCAAGACAGGCAAGGTGGGGCGCCCTTCCAAGTACGACGTCCGGGGCATCCAGAAGCCAGGCCCCGCCAAGGTTCCGCCCACCCCCAGCC
TGGCTCCCGCACCCCTCGCCAGCGTGCCCAGTGCCCCCAGCGCCCCCGGGCCAGGGCCAGAGCCTCCTGCCTCCCTGTCCTTCAACACTC
CCGAGTACCTGAAGTCAACCTTCTCCAAAACAGACTCCATCACCACGGGGACCGTCTCCACTGTCAAGAACGGACTGCCCACAGATAAAC
CAGCCGTCACTGAAGATGTAAACATTTACCAGAAATATATTGCCAGGTTCTCGGGCAGCCAGCACTGTGGCCACATCCACTGTGCCTACC
AGTACCGCGAGCACTACCACTGCCTTGACCCTGAGTGTAACTACCAGAGGTTCACGAGTAAGCAGGACGTGATCCGCCACTACAACATGC
ACAAGAAGCGCGACAACTCCCTGCAGCACGGCTTCATGCGTTTCAGCCCGCTGGACGACTGCAGCGTCTACTACCACGGCTGCCACCTCA
ATGGGAAGAGCACCCACTATCACTGCATGCAGGTGGGCTGTAACAAGGTGTACACGAGCACGTCTGACGTGATGACCCACGAGAACTTCC
ACAAGAAGAATACCCAGCTCATTAACGACGGCTTCCAGCGCTTCCGAGCCACCGAAGACTGTGGCACAGCCGACTGCCAGTTCTACGGAC
AGAAGACCACGCACTTCCACTGCAGGCGCCCCGGCTGCACATTCACTTTCAAGAACAAGTGTGACATCGAGAAGCACAAGAGCTACCACA
TCAAGGACGATGCCTACGCCAAGGACGGCTTCAAGAAGTTCTACAAGTACGAGGAGTGCAAGTACGAGGGCTGCGTGTACAGCAAGGCTA
CCAACCACTTCCACTGCATCCGCGCCGGCTGCGGCTTCACCTTCACCTCCACCAGCCAGATGACCTCTCACAAGCGCAAGCATGAGCGCC
GGCACATCCGCTCCTCGGGCGCGCTGGGGCTGCCGCCCTCGCTGCTGGGCGCCAAGGACACGGAGCACGAGGAGTCCAGCAACGACGACC
TTGTTGACTTCTCCGCCCTGAGCAGCAAGAACTCCAGCCTGAGCGCCTCCCCTACCAGCCAGCAGTCCTCTGCGTCCCTGGCTGCCGCCA
CTGCCGCCACCGAGGCTGGGCCCAGTGCCACCAAACCTCCCAACAGCAAGATCTCGGGGCTGCTGCCCCAGGGCCTGCCTGGCTCAATCC
CCCTGGCCCTGGCCCTCTCCAACTCGGGCCTGCCCACCCCCACGCCCTACTTCCCCATACTGGCTGGCCGTGGGAGCACCTCCCTGCCTG
TGGGCACCCCCAGCCTCCTGGGTGCCGTGTCGTCTGGGTCAGCAGCCTCAGCCACCCCTGACACACCCACGCTGGTCGCCTCGGGAGCTG
GAGACTCAGCCCCCGTGGCTGCCGCCTCTGTCCCGGCACCACCCGCCTCCATCATGGAGAGGATCTCTGCAAGCAAGGGCCTCATCTCGC
CCATGATGGCCAGGCTGGCTGCAGCTGCCCTCAAGCCCTCTGCCACCTTTGACCCAGGAAGCGGGCAGCAGGTCACCCCAGCCAGGTTCC
CCCCGGCCCAAGTGAAGCCGGAACCCGGTGAGAGCACCGGCGCCCCAGGCCCCCACGAAGCCTCCCAGGACCGCAGTCTAGACCTGACTG
TGAAGGAGCCCAGCAACGAATCAAATGGCCACGCAGTCCCGGCAAATTCATCTCTTTTATCCTCGCTTATGAATAAGATGTCTCAGGGCA
ACCCTGGCCTGGGCAGCCTGCTGAACATCAAGGCGGAAGCGGAGGGGAGCCCCGCTGCGGAGCCCTCGCCCTTCCTAGGCAAGGCCGTGA
AGGCGCTGGTTCAGGAGAAGTTGGCAGAGCCCTGGAAGGTGTACCTGCGCAGGTTTGGTACAAAGGACTTCTGTGACGGCCAGTGTGACT
TCCTCCACAAGGCCCACTTCCACTGCGTGGTGGAGGAATGCGGCGCGCTCTTCAGCACCTTGGACGGGGCCATCAAGCACGCAAACTTCC
ACTTCCGGACAGAGGGAGGAGCAGCAAAAGGAAACACAGAGGCTGCCTTTCCGGCCTCGGCCGCCGAGACCAAACCTCCCATGGCCCCCT
CGTCCCCTCCGGTCCCTCCTGTCACCACGGCCACGGTGTCCTCTCTGGAGGGGCCCGCTCCCAGCCCGGCCTCCGTGCCCTCCACCCCCA
CCCTGCTCGCCTGGAAGCAGCTGGCTTCCACCATACCCCAGATGCCTCAGATCCCAGCGTCAGTGCCTCACCTGCCCGCCTCGCCCTTGG
CAACGACTTCTCTAGAGAACGCCAAGCCCCAGGTCAAACCCGGATTCCTCCAGTTCCAGGAGAAGTGAGTCCCTCGATGAGCCGGGAGTC
CCGCGTTCCCCTCGCGTCTCGGGAGTAGGTGCTAGCAAGGGCGCTAGGAGGCCCTGTTCCTCACTGCGGATGGTGCTGCTGTCCCCAGCC
TCTCTGGGGCATGGCCATCGGGTGATGTCCTTCTAGCCAAAGATGCTGCTGCTCCTACCTCACTGCCTGTCCCAGAGCAGGCCAGCCCGC
GTGGGCCGATGGTGGCGGCAGTGGCTACTGCTCCTGCAGGGCATGTGGTGATCCTGCCAGGGCCAGGTGGGGTGGACTGGGCGTGGTGGT
CCTCAGAGGACAACTCCCAGCCTGACAAGGAGGGCTGCGTCTCCCTCCGAGCCTCCGTATTGGCCTCCTCTGTGGCTCACACCCATGGCT
GAATCTCTGCAGGGCACGTGAAGTCACGGGTAGGGGCCAGGCCCCTCCAGGCCGTCACTGGCCTGCACAGTGGTCTGAGCTCTTGGGTGG
AAGGGACCCTCCTCACTGGATGGTGGTGGCTCCTTGCAGGGAGAACGGTGACTTTGTATTGTCATGTGTGCGGCTTCCTGTTCTCAATAA


Top

FusionGenePPI for OBSCN_CASZ1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
OBSCNANK1, TTN, KCTD6, MPG, MOV10, NXF1, BRCA1, HNRNPD, HSF2, PCNA, RPA1, KIAA1107, C10orf12, VPS18, CDCA5, NPPA, LYPD4, UBE2ACASZ1APP, EED, BAG4, BCAR3, ESR2, PALB2, PPM1D, PTPN1, RAF1, WT1, TEAD2, TRIM25


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

RelatedDrugs for OBSCN_CASZ1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

RelatedDiseases for OBSCN_CASZ1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource